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1 CTP class B (HR 16.5; 95% CI 3.4-68.2; P < 0.0001) and p
2 CTP images were analyzed quantitatively for the presence
3 CTP images were evaluated qualitatively and independentl
4 CTP not only allows early detection of cerebral ischemia
5 CTP originates from two sources: a salvage pathway and a
6 CTP synthase activity is a potentially important step fo
7 CTP synthase is an ideal model system for addressing thi
8 CTP Synthetase (CtpS) is a universally conserved and ess
9 CTP was a better predictor of myocardial ischemia, with
10 CTP was assessed using the visual perfusion assessment.
11 CTP was available and assessable for 591 (34%) patients
12 CTP was performed and K(trans) maps were used to assess
13 CTP:phosphocholine cytidylyltransferase (CCT) interconve
14 CTP:phosphocholine cytidylyltransferase (CCT) is the key
15 CTP:phosphocholine cytidylyltransferase (CCT), an amphit
16 CTP:phosphocholine cytidylyltransferase (CCT), the rate-
17 CTP:phosphocholine cytidylyltransferase-alpha (CCTalpha)
18 CTP:phosphoethanolamine cytidylyltransferase (ET), encod
19 CTP:phosphoethanolamine cytidylyltransferase (Pcyt2) is
20 CTPs were developed for nine cationic metals (Cd, Cr(III
21 P = .0333) independent of BCLC ( P < .0001), CTP ( P < .0001), alpha-fetoprotein ( P < .0001), geogra
22 entage of small platelets (%SP) (P = 0.002), CTP-B (P = 0.003) and CTP-C (P = 0.003) compared to CTP-
23 is of the X-ray structures revealed that (1) CTP and dCTP bind in a very similar fashion, (2) UTP, in
28 to predict yields of these pollutants from 2-CTP up to approximately 1200 K, that is, prior to the em
29 (24 weeks treatment); 19 (95%, 78-100) of 20 CTP-B patients (12 weeks treatment); 20 (100%, 86-100) o
30 12 weeks treatment); 20 (100%, 86-100) of 20 CTP-B patients (24 weeks treatment); one (50%, 3-98) of
31 24 weeks of treatment; 17 (85%, 66-96) of 20 CTP-C patients (12 weeks treatment); and 18 (78%, 60-91)
32 was achieved by 20 (87%, 90% CI 70-96) of 23 CTP-B patients with 12 weeks of treatment; 22 (96%, 81-1
33 2 weeks of treatment; 22 (96%, 81-100) of 23 CTP-B patients with 24 weeks of treatment; 17 (85%, 66-9
35 (12 weeks treatment); 27 (96%, 84-100) of 28 CTP-A patients (24 weeks treatment); 19 (95%, 78-100) of
36 24 weeks treatment); 30 (100%, 91-100) of 30 CTP-A patients (12 weeks treatment); 27 (96%, 84-100) of
38 (Child-Turcotte-Pugh [CTP] class A, n = 564; CTP class B/C, n = 175), 90% achieved sustained virologi
40 :Alberta Stroke Program Early CT Score >= 6, CTP:regional cerebral blood flow (<30%) < 70ml with mism
42 iments with cyclopentenyl cytosine (CPEC), a CTP synthetase inhibitor and cytosine, suggest that the
46 patients who had either no cirrhosis; CTP-A, CTP-B, or CTP-C cirrhosis; or fibrosing cholestatic hepa
49 was 16/843 (2%), significantly higher among CTP class B/C versus CTP class A patients (6.4% versus 0
50 ets (%SP) (P = 0.002), CTP-B (P = 0.003) and CTP-C (P = 0.003) compared to CTP-A had higher probabili
51 CTA (area under the curve [AUC] = 0.844) and CTP + CTA (AUC = 0.845) had comparable per-vessel diagno
52 rates were observed between CTP class A and CTP class B/C patients (94% versus 78%, and 4% versus 14
53 imaging evaluation (CT, CT angiography, and CTP with Rapid Processing of Perfusion and Diffusion sof
54 c (sphinganine) lipids, nucleotides (ATP and CTP), N-ethylmaleimide, propranolol, phenylglyoxal, and
56 calcification or artefact, TAG320 + CTA and CTP + CTA provide comparable diagnostic accuracy for fun
58 as BD and had both CT angiography (CTA) and CTP imaging in the same session were retrospectively rev
59 row computed tomography (TAG320) + CTA, and CTP + TAG320 + CTA (multidetector computed tomography-in
61 we demonstrate the excitation of dipolar and CTP resonant modes in metallic nanodimers bridged by pha
63 ing conserved prokaryotic choline kinase and CTP:phosphocholine cytidylyltransferase activities with
68 e, analog nucleotides including GTP, UTP and CTP, do not show serious interferences and this sensor r
70 ically, dGTP-activated SAMHD1 hydrolyzes Ara-CTP, which results in a drastic reduction of Ara-CTP in
71 utically active triphosphate metabolite, Ara-CTP, which exerts antileukemic effects, primarily by inh
72 on) over a linear concentration range of ara-CTP (0.05-0.5 microM), and detection is independent of r
74 of the NTP, including 2',3'-ddCTP, arabinose-CTP, and 2'-O-methyl-CTP, inhibit polymerase, whereas 2'
79 d patients with Child-Turcotte-Pugh class B (CTP-B) or CTP-C cirrhosis who had not undergone liver tr
81 VR12 and relapse rates were observed between CTP class A and CTP class B/C patients (94% versus 78%,
82 speed of the HMS operation could allow both CTP isolation and engraftment during a single surgical p
84 phatidylcholine biosynthesis is catalysed by CTP: phosphocholine cytidylyltransferase (PfCCT), which
85 olipid, phosphatidylcholine, is catalyzed by CTP:phosphocholine cytidylyltransferase (CCT), which is
89 A binding activity of RbkR was stimulated by CTP and suppressed by FMN, a product of riboflavin kinas
90 thrombectomy or standard medical therapy, by CTP as relative cerebral blood flow less than 30% of nor
93 oproteinases (MMPs) and cysteine cathepsins (CTPs) subsequent to application of a filler-free (Res.A)
94 otte score, CTP) and Child-Pugh B cirrhosis (CTP 7-9) in patients with advanced hepatitis C virus (HC
95 tect the presence of Child-Pugh B cirrhosis (CTP 7-9) were IP-10 (p-value= 0.008) and IL-6 (p-value=0
97 related to the severity of liver cirrhosis (CTP score), mainly IP-10 and IL-6, which discriminated p
98 tation patients who had either no cirrhosis; CTP-A, CTP-B, or CTP-C cirrhosis; or fibrosing cholestat
100 argue that the regulatory sites that control CTP synthase function, but not enzymatic activity per se
102 .1 years, 68.5% male) who received Stroke-CT/CTP-imaging between 2010 and 2018 with occlusion of the
107 eiver-operating characteristic curve for CTA/CTP (0.82, 95% CI: 0.69 to 0.95) was superior to that fo
108 The per-patient diagnostic accuracy of CTA/CTP for stents (87%, 95% confidence interval [CI]: 78% t
109 otentials (CTP) for nanoparticles and derive CTP values for TiO2 nanoparticles (TiO2-NP) for use in L
111 endent formation of 3'-deoxy-3',4'-didehydro-CTP (ddhCTP), which inhibits some viral RNA polymerases.
112 yme converts CTP to 3'-deoxy-3',4'-didehydro-CTP, which functions as novel chain-terminating antivira
114 etween nanodisks and formation of a distinct CTP peak at longer wavelengths (lambda 1.85 mum) far fro
116 sis incidence rates were calculated for each CTP level, overall and for each of the 10 leading seroty
118 ed direct inhibition of the cytosolic enzyme CTP:phosphoethanolamine cytidylyltransferase (PCYT2).
119 375575), a specific inhibitor of the enzyme CTP synthetase, induces irreversible growth arrest and s
120 s of a key phospholipid biosynthetic enzyme (CTP:phosphocholine cytidylyltransferase alpha) and alter
121 tem (PDE, adenylate kinase (AK) using excess CTP instead of ATP as substrate, pyruvate kinase (PK), a
123 dence rates (favorable CT = 56% vs favorable CTP = 57%, adjusted odds ratio [aOR] = 1.91, 95% confide
124 whom 87.0% had favorable CTs, 91% favorable CTPs, 81% both favorable profiles, 16% discordant, and 3
127 n an error-free manner, with specificity for CTP incorporation being essentially the same as for unda
132 l independence was worse in patients who had CTP versus those who had diffusion MRI, after adjustment
134 Children and older adults living in higher CTP have had a higher incidence of domestically-acquired
136 age-adjusted incidence occurred with higher CTP level (p<0.001, relative risk (RR) for highest (>20%
141 0-row computed tomography perfusion imaging (CTP) to detect atherosclerosis causing myocardial ischem
142 us adverse events (SAEs) were more common in CTP class B/C versus CTP class A patients (50% versus 12
144 S in patients who were HIV-positive included CTP ( P = .0071) and alpha-fetoprotein ( P < .0001).
145 actions for all parameters tested, including CTP prevalence (CTPs per 10(6) nucleated cells), prolife
146 duced likelihood of functional independence (CTP OR 0.77 [0.69-0.86] per 10 mL, p(interaction)=0.29;
147 lite prodrug 3-deazauridine (3DUrd) inhibits CTP synthetase upon intracellular conversion to its trip
151 2',3'-ddCTP, arabinose-CTP, and 2'-O-methyl-CTP, inhibit polymerase, whereas 2'-amino-CTP is incorpo
152 dings in the context of our homology-modeled CTP as it cycles between the outward-facing, occluded, a
154 l performance was superior to MELD, MELD-Na, CTP, and MRS at all time points (e.g., 30-day postoperat
155 pectrometry and one- and two-dimensional NMR CTP:glucose-1-phosphate cytidylyltransferase, CDP-Glc 4,
156 CTPS) is the rate-limiting enzyme in de novo CTP synthesis and is required for the formation of RNA,
157 could now be elicited by other nucleotides (CTP and ADP) that are not normally effective as P2X rece
160 complexes stall after successful addition of CTP opposite the phenanthriplatin-dG adduct in an error-
162 he binding of UTP can enhance the binding of CTP and why UTP binds more tightly in the presence of CT
166 in pah1 pah2 is suppressed by disruption of CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE1 (CCT1), which e
169 rovide further insight into the mechanism of CTP-mediated chloroplastic localization, and more import
170 gistically inhibit ATCase in the presence of CTP, we determined a series of X-ray structures of ATCas
175 the synthesis and conformational studies of CTP mimics, having nonconstrained alpha(3)beta motif, th
177 Level 1 data regarding the optimal timing of CTP in major colorectal surgery and the incidence of OP-
181 tients with large baseline ischemic cores on CTP undergoing ET with the outcomes of matched controls
182 baseline ischemic core greater than 50 mL on CTP at a tertiary care center from May 1, 2011, through
186 r 100-fold GTP-specificity over GDP, ATP, or CTP and was used to develop a heterogeneous time-resolve
187 with Child-Turcotte-Pugh class B (CTP-B) or CTP-C cirrhosis who had not undergone liver transplantat
188 ho had either no cirrhosis; CTP-A, CTP-B, or CTP-C cirrhosis; or fibrosing cholestatic hepatitis.
190 fashion, (2) UTP, in the presence of dCTP or CTP, binds at a site that does not overlap the CTP/dCTP
192 articipants who developed clinical outcomes [CTP > 7, ascites, encephalopathy, variceal bleeding, SBP
193 , and a highly conserved C-terminal peptide (CTP) motif that mediates a wide array of protein-protein
198 angiography (CTA) and stress-rest perfusion (CTP) with cardiac magnetic resonance myocardial perfusio
200 y of combined computed tomography perfusion (CTP) + computed tomography angiography (CTA), translumin
201 nsitive (ATS) computed tomography perfusion (CTP) algorithms in Philips IntelliSpace Portal (v9, ISP)
202 n rest/stress computed tomography perfusion (CTP) and SPECT-MPI, but the value of resting CTP (rCTP)
203 derived from computed tomography perfusion (CTP) imaging, can predict hemorrhagic transformation (HT
205 same baseline computed tomography perfusion (CTP) ischemic core threshold to predict infarction as th
206 ng myocardial computed tomography perfusion (CTP) to computed tomography angiography (CTA) improves d
210 ference in preoperative versus postoperative CTP with respect to early postoperative DVT [3/184 (1.6%
211 factors or comparative toxicity potentials (CTP) for nanoparticles and derive CTP values for TiO2 na
213 ated marine comparative toxicity potentials (CTPs) or ecotoxicity characterization factors for metals
214 re geocoded, linked to census tract poverty (CTP) level, then categorized into four CTP-level groups.
217 -based analysis of coregistered pretreatment CTP and 24-hour diffusion-weighted imaging (DWI) was the
218 parameters tested, including CTP prevalence (CTPs per 10(6) nucleated cells), proliferation by colony
219 of 12-, 13-, and 14-membered natural product CTPs and their novel analogues are presented, with parti
220 eloped that enable access to natural product CTPs and their rationally designed synthetic analogues h
223 tween innovation and cap-and-trade programs (CTPs)--the world's most prominent climate policy instrum
227 a (n = 1,168 [74%]) and Child-Turcotte-Pugh (CTP) class B (median score, 7; interquartile range [IQR]
228 ith decompensation were Child-Turcotte-Pugh (CTP) class B versus A (hazard ratio [HR] 7.7; 95% CI 3.3
231 survival until day 60; Child-Turcotte-Pugh (CTP), Model for End-Stage Liver Disease (MELD), and Sequ
232 atients with cirrhosis (Child-Turcotte-Pugh [CTP] class A, n = 564; CTP class B/C, n = 175), 90% achi
234 for 2 months; it also significantly reduces CTP, MELD, and SOFA scores and prevents the development
237 CTP) and SPECT-MPI, but the value of resting CTP (rCTP) in acute chest pain triage remains unclear.
238 oroplasts, but for other proteins these same CTPs have reduced localization efficiencies or fail comp
239 ry review, with a Child-Turcotte-Pugh score (CTP) of A or B, ECOG performance status of 0 to 2, no ex
240 (assessed by the Child-Pugh-Turcotte score, CTP) and Child-Pugh B cirrhosis (CTP 7-9) in patients wi
241 beta-turn to gamma-turn structure in similar CTPs by inverting the chirality of beta(3) carbon in C-l
243 el CT techniques, including adenosine stress CTP and TAG320, may improve the diagnostic accuracy of C
244 l was nondiagnostic on CTA, adenosine stress CTP in the corresponding myocardial territory was read f
246 ugh empirical evidence drawn from successful CTPs for sulfur dioxide and nitrogen oxide control.
247 in the CDP-choline pathway for PC synthesis, CTP:phosphocholine cytidylyltransferase alpha (CCTalpha)
248 erged to establish the cyclic tetrapeptides (CTPs) as the primary determinant of both potency and sel
257 Single turnover kinetic studies showed that CTP is incorporated with apparent K(d) and k(pol) values
262 k1 diacylglycerol (DAG) kinase catalyzes the CTP-dependent phosphorylation of DAG to form phosphatidi
263 -encoded diacylglycerol kinase catalyzes the CTP-dependent phosphorylation of diacylglycerol to form
264 sis pathway that depends on two enzymes, the CTP synthases (or synthetases) 1 and 2 (CTPS1 with CTPS2
266 ariability of 3.5 orders of magnitude in the CTP of Cu is mainly associated with the variability in s
267 variability of 3 orders of magnitude in the CTP of Ni can mainly be explained by differences in pore
268 glimpse into the architectural design of the CTP complex and reveals unique interactions that are imp
269 scription factor Gln3 or inactivation of the CTP synthetase Ura7 both resulted in the activation of t
271 P, binds at a site that does not overlap the CTP/dCTP site, and (3) the triphosphates of the two nucl
272 cts as a spacer that spatially separates the CTP sticker from the core, thus ensuring filament format
276 associations of these polymers, whereas the CTP promotes the formation of alternative assemblies.
277 ng the GM/WM density ratio together with the CTP results increased the sensitivity further to 98%.
278 le shows that before trading began for these CTPs, analysts overestimated the value of allowances in
282 The nucleotide cytidine 5' triphosphate (CTP) is a precursor required for the metabolism of DNA,
283 yze the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP), a previou
285 (24 weeks treatment); one (50%, 3-98) of two CTP-C patients (12 weeks treatment); and four (80%, 34-9
291 etal artifacts [75%] or motion [25%]) versus CTP (1%; p < 0.001; severe angina precluded CTP in 1 cas
292 Es) were more common in CTP class B/C versus CTP class A patients (50% versus 12%, respectively; P <
293 nificantly higher among CTP class B/C versus CTP class A patients (6.4% versus 0.9%; P < 0.001).
294 a acidophilum was determined in complex with CTP and its DNA operator revealing key residues for oper
295 o found to catalyze cytidylation of FMN with CTP, making the modified FAD, flavin cytidine dinucleoti
296 , while large differences were observed with CTP values for TiO2 nanoparticles published in earlier s
298 n of the Escherichia coli class III RNR with CTP (substrate) and ATP (allosteric effector) in the abs
300 s appeared plausible after benchmarking with CTPs for other nanoparticles and substances present in t