ライフサイエンスコーパス: Cyt

1 Cyt b showed a similar pattern, but was confounded by so

2 Cyt b(5) is the electron-carrier "repair" protein that r

3 Cyt c H19M, the first bis-Met liganded cyt c, is compare

4 Cyt c has also been shown to demonstrate peroxidase-like

5 Cyt c has multiple other functions including ROS product

6 Cyt c is observed to retain its native FeII/III electron

7 Cyt c is tightly regulated by allosteric mechanisms, tis

8 Cyt c(T)-null mice often exhibit early atrophy of the te

9 Cyt c, a heme containing metalloprotein is located in th

10 Cyt c-catalyzed peroxidase reactions show an initial lag

11 Cyt c2 reduces the photo-oxidized RC donor (D+), a bacte

12 Cyt f residues involved in binding PC, in the absence of

13 Cyt f-PC and cyt f-cyt c(6) showed the same types of int

14 Cyt P450 enzymes were activated via the NADPH/reductase

15 Cyt P450cam and cyt P450 1A2 showed 3-fold higher activi

16 Cyt toxins play an important role in mosquitocidal activ

17 Cyt-c is found to interact primarily with the membrane i

18 We find that (1) Cyt c can be reversibly denatured and renatured, dependi

19 thesized, Lac4-Cyt-c, Lac9-Cyt-c, Dex5(10kD)-Cyt-c, Dex8(10kD)-Cyt-c, and Dex3(1kD)-Cyt-c.

20 -c, Lac9-Cyt-c, Dex5(10kD)-Cyt-c, Dex8(10kD)-Cyt-c, and Dex3(1kD)-Cyt-c.

21 10kD)-Cyt-c, Dex8(10kD)-Cyt-c, and Dex3(1kD)-Cyt-c.

22 uc) increased to higher levels than [Ca(2+)](Cyt) immediately adjacent to the outer membrane of the n

23 at alternative mechanisms can yield [Ca(2+)](Cyt) oscillations in non-excitable cells, and, under cer

24 of cytosolic Ca(2+) concentration ([Ca(2+)](Cyt)) oscillations.

25 the ud), allowed for generation of [Ca(2+)](Cyt)oscillations driven by distinct mechanisms at variou

26 ining methods have been used to identify 356 Cyt P450 genes and 99 related pseudogenes in the rice (O

27 -transfer paths involving cytochrome b(559) (Cyt b(559)), chlorophyll (Chl), and beta-carotene (Car)

28 ocyte membranes contain a cytochrome b(561) (Cyt b(561)) and hypothesize that it may be responsible f

29 on these data, a standard curve up to 2.5muM Cyt c was established.

30 , and half-maximal turnover is observed at a Cyt c substrate concentration of 5.5 microM compared to

31 xa with an efficiency approximately 80% of a Cyt/Oxa (C/O) base pair.

32 In addition, Cyt toxins also display haemolytic activity.

33 pha, Caspase-8, mitochondrial absorbance and Cyt-c were all similar in Lac + Hyd and M-Post groups.

34 The kinetics of Alt and Cyt pathway activity in relation to UQ(r)/UQ(t) were not

35 ortional change per 10 degrees C) of Alt and Cyt pathway respiration in cotyledon slices (Q(10) = 1.9

36 , 3-aminopropyl triethoxysilane (APTES), and Cyt-C antibody.

37 thuringiensis produces insecticidal Cry and Cyt proteins that are toxic to different insect orders.

38 Cry and Cyt toxins interact by specific epitopes, and this inter

39 tion of genes encoding both plastocyanin and Cyt c6 in algal and cyanobacterial genomes might be beca

40 etreault et al. by measuring k(2) for RC and Cyt molecules with modified charged residues at the bind

41 so called CycH), is thought to act as an apo-Cyt c chaperone.

42 res at least 10 essential components for apo-Cyt c chaperoning, thio-oxidoreduction, and the delivery

43 refore suggest that CcmI, along with its apo-Cyt chaperoning function, is also critical for the effic

44 ctron transfer from DNA/AgNCs to the aptamer-Cyt c complex.

45 ve expressed one of the putative Arabidopsis Cyt b561 genes (CYBASC1) in yeast and we demonstrate tha

46 AtProRS-Cyt mRNA is more highly expressed in roots than in cotyl

47 AtProRS-Cyt showed nearly identical substrate specificity for L-

48 ed in chloroplasts/mitochondria, and AtProRS-Cyt (At3g62120) is cytosolic.

49 from lower amino acid specificity of AtProRS-Cyt.

50 ed from the C-terminal half of cytochrome b (Cyt b) encoded by the mitochondrial genome.

51 poptosis due to an increase of cytochrome b (Cyt b) expression and its release from mitochondria.

52 cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene markers, we inferred the origins and incursi

53 integral membrane protein flavocytochrome b (Cyt b) is the catalytic core of the human phagocyte NADP

54 integral membrane protein flavocytochrome b (Cyt b) is the catalytic core of the phagocyte NADPH oxid

55 ntegral membrane protein (flavocytochrome b (Cyt b)) that generates superoxide and initiates a cascad

56 e the rate of electron transfer (ET) between Cyt c(Fe(2+)) and Co(phen)(3)(3+) by a factor of 10(5) t

57 th strong electrostatic interactions between Cyt on the M subunit side of the RC surface.

58 ress a testis-specific form of cytochrome c (Cyt c(T)) that is distinct from the cytochrome c express

59 ss as shown by increased HSP60/Cytochrome C (Cyt C) and CHOP-ATF3 levels respectively.

60 rst time that the heme protein cytochrome c (Cyt c) can enter the interior of a MOF despite the large

61 The active site of cytochrome c (Cyt c) consists of a heme covalently linked to a pentape

62 es and the native structure of cytochrome c (Cyt c) from Saccharomyces cerevisiae.

63 Cytochrome c (Cyt c) has evolved to become an important electron-trans

64 Mammalian cytochrome c (Cyt c) has two primary functions: transfer of electrons

65 CRALBP and cytochrome C (Cyt C) immunolabeling revealed that hyperreflective band

66 It is well known that cytochrome c (Cyt c) is a crucial death regulator that triggers progra

67 Cytochrome c (Cyt c) is an apoptosis-initiating protein when released

68 Cytochrome c (Cyt c) is an important biomarker in cell lysates for the

69 Cytochrome c (Cyt c) is commonly used as intrinsic biomarker for sever

70 R) measurements of yeast iso-1-cytochrome c (Cyt c) on a gold surface.

71 Cytochrome c (Cyt c) plays a vital role in the mitochondrial electron

72 xperiments have shown that the cytochrome c (Cyt c) protein consists of five cooperative folding-unfo

73 To promote studies of cytochrome c (Cyt c) ranging from apoptosis to protein folding, a syst

74 uces apoptosis, which involves cytochrome c (Cyt c) release from mitochondria and subsequent apoptoso

75 aneous reversible unfolding of Cytochrome c (Cyt c) under native conditions have led to the following

76 ble unfolding and refolding of cytochrome c (Cyt c) under native conditions.

77 rein, the structural change of cytochrome c (Cyt c) upon encapsulation within a hierarchical metal-or

78 f the simple, globular protein cytochrome C (Cyt C) with MPMN surfaces using experimental protein ass

79 prevent apoptosis triggered by cytochrome c (Cyt c).

80 zation free energy (lambda) of cytochrome c (Cyt) in electrostatic complexes that mimic some basic fe

81 behavior of the redox protein cytochrome c (Cyt-C) onto different interfaces, namely, bare-ITO, 3-am

82 arious standard proteins (e.g. cytochrome C (Cyt-C), myoglobin (MYO) and bovine serum albumin (BSA))

83 edox cofactors namely oxidized cytochrome-c (Cyt-c) and Co-enzyme-Q (Co-Q) immobilized on Quantum dot

84 that unfolded horse heart ferricytochrome c (Cyt c) is a novel chromophoric probe for investigation o

85 Gly](3-) = RuCE(5)G, and ferricytochrome c = Cyt c.

86 Cytochrome c' (Cyt c') is a c-type cytochrome with a pentacoordinate he

87 Lys and five modified Rhodobacter capsulatus Cyt c2 molecules in which positively charged Lys residue

88 cytokinesis block micronucleus cytome (CBMN-Cyt) assay with WIL2-NS B lymphoblastoid cells to test t

89 the cytochrome c expressed in somatic cells (Cyt c(S)).

90 eight of which were new to our 97 global COI-Cyt b haplotype database.

91 (COX) alone (Q(10) = 2.08) and the complete Cyt pathway (Q(10) = 2.40-2.55).

92 nducing factor (AIF) and cytochrome complex (Cyt c) is reduced in Glu(-) cells, even though cell deat

93 duction by this multisubunit enzyme complex, Cyt b-specific monoclonal antibodies (mAbs) and the p47p

94 esidues of PsbP, 'pN15', was able to convert Cyt b559 into its HP form.

95 PSI), photosystem II (PSII), and cytochrome (Cyt) b6f within thylakoid membranes at the molecular lev

96 erature on alternative (Alt) and cytochrome (Cyt) pathway respiration, both in intact tissues and iso

97 ectron transfer reaction between cytochrome (Cyt) c(2) and reaction center (RC) from photosynthetic b

98 of PsbP and the alpha subunit of Cytochrome (Cyt) b559 (PsbE).

99 th a heme-containing substitute, cytochrome (Cyt) c6.

100 ogenitors (OPs) in proinflammatory cytokine (Cyt-Mix)-treated CNS glial cells, which is a condition s

101 d of three-domain Cry proteins and cytolytic Cyt toxins, which are toxic to different mosquito larvae

102 hate is only incorporated opposite cytosine (Cyt).

103 ucleophilic attack of Cys(1226) to cytosine (Cyt) C6, methyl transfer from S-adenosyl-l-methionine (S

104 lus, with inflammatory cytokine-treated DCs (Cyt-DCs) being the most effective Treg inducers.

105 forming the final heme ligation steps during Cyt c biogenesis.

106 and 3,N(4)-epsilon-cytosine (3,N(4)-epsilon-Cyt)] and their corresponding 2'-deoxynucleosides.

107 gh yields of recombinant eucaryotic (equine) Cyt c.

108 '-bithienyl)-(4-carboxyphenyl)methane ester (Cyt-S4), revealed Watson-Crick type nucleobase pairing o

109 5+/-0.08 per electron, compared to DeltaZ(ET(Cyt-c)) =1.19+/-0.02).

110 ) were chemically coupled to surface exposed Cyt c lysine (Lys) residues using succinimidyl chemistry

111 otosystem I (PSI) and the cytochrome b(6)/f (Cyt b(6)/f) complex.

112 the important role of lysine in facilitating Cyt C adsorption to MPMN surfaces.

113 similar to the other members of the family, Cyt.c(550) has a midpoint potential (E(m7) = -250 mV) th

114 we demonstrate that the photocycle of ferric Cyt c is entirely due to a cascade among excited spin st

115 th thioglycolic acid (TGA) as a fluorometric Cyt c nanosensor.

116 P@Cit/BSA-FITC), low limits of detection for Cyt c (LOD = 370 pM) and for BSA (LOD = 1.8 nM) have bee

117 Much related information for Cyt c strongly conforms with this mechanism.

118 The proposed method for Cyt c detection may also be useful for the study of thos

119 T) in germ cells, we generated mice null for Cyt c(T).

120 this probe showed a linear dynamic range for Cyt c from 175 to 1750 pM with a detection limit of 32.7

121 The linear range for Cyt c was found to be 0-10 muM for Hb/AuNCs and from 0 t

122 Sperm from Cyt c(T)-null mice contained a greater number of immotil

123 ions employing rigid-backbone coarse-grained Cyt C and MPMN models indicate a monotonic increase in a

124 , similar to those of the chromaffin granule Cyt b(561).

125 The order of reaction determined was Gua>Thy>Cyt>Ade.

126 n in the minor groove at Ade/Thy- and/or Gua/Cyt-rich sequences.

127 denine, the molecules designed to target Gua/Cyt sequences also generate lesions at guanine; however,

128 olymerase iota extends from the N2-ethyl-Gua:Cyt 3' terminus more efficiently than from the Gua:Cyt b

129 terminus more efficiently than from the Gua:Cyt base pair.

130 wo main forms of GVHD occur: cytotoxic GVHD (Cyt GVHD), in which TNFalpha is a critical cytokine in e

131 n, is also critical for the efficacy of holo-Cyt c formation, possibly via its close interactions wit

132 There were no major changes in Cyt c activity upon glycosylation.

133 The increase in Cyt c' under this condition was higher than would be pre

134 the dominance of hydrophilic interactions in Cyt C-MPMN binding.

135 one of the four tyrosine residues present in Cyt c.

136 uced binding to HSP, leading to reduction in Cyt b transcription.

137 ion antagonizes NF-kappaB transactivation in Cyt-Mix-treated astrocytes.

138 is a potentially valuable method to increase Cyt c stability during formulation and storage and poten

139 fect the fractional yield of a heme inverted Cyt c isoform.

140 d suggest a novel cellular complex involving Cyt c and tiRNAs that inhibits apoptosome formation and

141 We have isolated Cyt c from cow heart under conditions that preserve the

142 Incubation of Dex3(1 kD)-Cyt c with mercaptoethanol caused significant loss in th

143 e neo-glycoconjugates were synthesized, Lac4-Cyt-c, Lac9-Cyt-c, Dex5(10kD)-Cyt-c, Dex8(10kD)-Cyt-c, a

144 onjugates were synthesized, Lac4-Cyt-c, Lac9-Cyt-c, Dex5(10kD)-Cyt-c, Dex8(10kD)-Cyt-c, and Dex3(1kD)

145 cytoplasmic expression of either full-length Cyt b or its C-terminal half in several human cell lines

146 more critical copper-dependent enzymes like Cyt oxidase and a ferroxidase.

147 aspase 8-dependent cleavage of mitochondrial Cyt b and translocation of its C-terminal half into the

148 age and cytoplasmic release of mitochondrial Cyt b.

149 In addition, non-modified Cyt c was more susceptible to denaturation by a water-or

150 aspase 3 activation compared to non-modified Cyt c.

151 Native Cyt c (104 residues) is composed of five cooperative fol

152 e reversible equilibrium unfolding of native Cyt c steps up through these intermediate forms to the u

153 racterizes the structure of human neutrophil Cyt b in both detergent micelles and reconstituted membr

154 conformational dynamics in human neutrophil Cyt b.

155 The precise mechanism of action of Cyt toxins is still debated, and two models have been pr

156 erimental assays revealed that adsorption of Cyt C generally increased with increasing surface polar

157 To initiate mass analysis of Cyt b post-translational modifications, the isolated gp9

158 ver nanoclusters (DNA/AgNCs) for analysis of Cyt c are presented.

159 This potential change of Cyt b559, in the absence of the C-terminal domain of Psb

160 uantification of different concentrations of Cyt c ranging from 0.5 - 2.5muM.

161 tics that saturate at high concentrations of Cyt c.

162 ubunit p47phox modulates the conformation of Cyt b (in addition to serving as an adapter protein) dur

163 CS9 and p47SH3AB altered the conformation of Cyt b.

164 xistence of two native-like conformations of Cyt that present significantly different lambda values.

165 Gibbs free energy change for denaturation of Cyt c on Au surface in water, DeltaG degrees (water), is

166 re to a urea solution causes denaturation of Cyt c, which shifts the minimum in the SPR curve to a la

167 ed and tested for the real-time detection of Cyt c in living cells.

168 gold electrode for impedimetric detection of Cyt c over the range of 0.15-375nM.

169 plicability in the fluorometric detection of Cyt c.

170 applied to the quantitative determination of Cyt c in cell lysates, which opens a new avenue to early

171 atozoa isolated from the cauda epididymis of Cyt c(T)-null animals were less effective in fertilizing

172 osphorylatable residue or over-expression of Cyt-PTPepsilon protects cells from injury.

173 A mutant form of Cyt c(551), V23DI59E, has significantly reduced ability

174 amma) antagonist revealed that inhibition of Cyt-Mix-induced iNOS expression and survival of differen

175 the first time demonstrate the inhibition of Cyt-Mix-induced NF-kappaB transactivation in CNS glial c

176 ibrosis rather than the epithelial injury of Cyt GVHD?

177 trates that tertiary structure intactness of Cyt c was essential for apoptosis induction.

178 We propose that interactions of Cyt with the natural redox partner proteins activate a s

179 l picture of the folding energy landscape of Cyt c.

180 However, covalent modification of Cyt c through phosphorylation has not yet been reported.

181 protein surface, where the redox partners of Cyt c bind.

182 The enhanced catalytic performance of Cyt c after being encapsulated within NU-1000 is support

183 Cyt c binds tiRNAs in vitro, and the pool of Cyt c-interacting RNAs binds tighter than individual tiR

184 In the presence of Cyt c, the triplet state lifetime of the ruthenium metal

185 that pN15 can modulate the redox property of Cyt b559 involved in the side-electron pathway in PSII.

186 thods were developed for the purification of Cyt b from PLB-985 membrane fractions in order to confir

187 Quantification of Cyt c within living cells via QDs is, however, influence

188 l time for the detection and quantitation of Cyt c from isolated mitochondria is only 20 min.

189 d electrostatic energies for a wide range of Cyt/RC configurations.

190 e dehydrogenase (FDH) catalyzed reduction of Cyt-c and Co-Q on the surface of QDs lead to fluorescenc

191 We discuss the complex regulation of Cyt c and propose that it is a central regulatory step o

192 in, which in turn can trigger the release of Cyt c from isolated mitochondria.

193 se-2 can also induce directly the release of Cyt c, AIF (apoptosis-inducing factor), and Smac (second

194 excessive ROS generation, and the release of Cyt c.

195 Distinct residues of Cyt c are modified by PTMs, primarily phosphorylations,

196 We examine the role of Cyt c PTMs, including phosphorylation, acetylation, meth

197 To examine the role of Cyt c(T) in germ cells, we generated mice null for Cyt c

198 7phox SH3 domains modulates the structure of Cyt b was obtained using a cell-free assay system where

199 Where the native structure of Cyt c requires sequential folding, in the first three st

200 We determined the 1.6 A x-ray structure of Cyt-CVNH, a recently identified lectin from the cyanobac

201 was always equal to, or higher than, that of Cyt c oxidase (COX) alone (Q(10) = 2.08) and the complet

202 IL-4 treatment of Cyt-Mix-treated CNS glial cells significantly decreased

203 apparent stoichiometry of approximately one Cyt c per proteasome can be formed and (2) when inhibiti

204 000ng/mL (LOD of 0.01ng/mL) using both QD-Ox-Cyt-c (R(2)=0.93) and QD-Ox-Co-Q (R(2)=0.96).

205 Two probes were designed, QD-Ox-Cyt-c and QD-Ox-Co-Q, which were found to quench the flu

206 r Oxa-containing double-stranded base pairs, Cyt/Oxa, Thy/Oxa, Ade/Oxa, and Gua/Oxa, with no preferen

207 the first direct analysis of human phagocyte Cyt b by matrix-assisted laser desorption/ionization and

208 ts cytoplasmic protein tyrosine phosphatase (Cyt-PTPepsilon), which specifically targets Y124.

209 In vivo phosphorylated Cyt c shows enhanced sigmoidal kinetics with COX, and ha

210 ut do not alter the thermophilic proteasome, Cyt c is extensively cleaved by the proteasome.

211 Furthermore, glycosylation protected Cyt c from detrimental effects by some stresses (i.e., e

212 ce coverage of the integral membrane protein Cyt b by mass spectrometry and provides analytical metho

213 llels between Mss116 and the related protein Cyt-19 from Neurospora crassa suggest that these protein

214 ironment favors the phosphorylation of a PSI-Cyt b(6)/f supercomplex to regulate PSI cyclic electron

215 The stability of the PSI-Cyt b(6)/f supercomplex was dependent upon the phosphory

216 phorylated proteins associated with this PSI-Cyt b(6)/f supercomplex, two 17-kD PSII subunit P-like p

217 of other thylakoid membrane complexes--PSII, Cyt b6/f, and ATP synthase, have minor (or no) reduction

218 rthermore, we functionally tagged PSI, PSII, Cyt b6f, and ATP synthase individually with fluorescent

219 Acute administration of cytisine or 3-pyr-Cyt did not affect ICSS thresholds.

220 The cytisine-derivative 3-pyr-Cyt is a very weak alpha4beta2* nAChR partial agonist an

221 derivative 3-(pyridin-3'-yl)-cytisine (3-pyr-Cyt) on brain reward function in nicotine-naive and nico

222 Varenicline and cytisine, but not 3-pyr-Cyt, diminished the nicotine withdrawal-induced elevatio

223 above results for functionally reconstituted Cyt b and provided evidence that binding of both mAb CS9

224 The TO ASC-reducible Cyt has a high specific activity, suggesting that it is

225 The caspase-2-released Cyt c is sufficient to activate the Apaf-caspase-9 apopt

226 the interaction of small RNAs with released Cyt c in a ribonucleoprotein (Cyt c-RNP) complex.

227 with released Cyt c in a ribonucleoprotein (Cyt c-RNP) complex.

228 ctrometry gave evidence that the sequestered Cyt c is essentially intact within the inhibited proteas

229 complex, a rapid turnover of the sequestered Cyt c occurs.

230 ipitation studies with detergent-solubilized Cyt b, the oxidase-inhibitory mAb CS9 was shown to share

231 To more directly study Cyt c intermediates and pathways during normal energetic

232 on pathways become restricted for sufficient Cyt c production.

233 road perspective, this work on novel s-SWCNT/Cyt c nanohybrid infrared detectors has developed a succ

234 sing these building blocks, uncooled s-SWCNT/Cyt c thin film infrared detectors were synthesized and

235 tion and polarization was examined using TCR-Cyt-5CC7-I transgenic recombination activating gene-2-/-

236 When an oxanine base is in a DNA template, Cyt is efficiently incorporated opposite the template ox

237 at, unlike azurin, cytochrome c(551), termed Cyt c(551), has very little ability to induce apoptosis

238 We also demonstrate that Cyt c binds tiRNAs in vitro, and the pool of Cyt c-inter

239 lar dichroism (CD) spectra demonstrated that Cyt c glycosylation did not cause significant changes to

240 ce analysis of whole cells demonstrated that Cyt c' binds NO during denitrification.

241 s and purified protein did not indicate that Cyt c' has NO reductase activity.

242 It was proposed that Cyt toxins do not interact with protein receptors but di

243 own under different conditions revealed that Cyt c' levels were highest during photosynthetic denitri

244 Accumulated results now show that Cyt c is composed of five individually cooperative foldi

245 HIV assays showed that Cyt-CVNH is able to inhibit HIV-1 with approximately 4-f

246 t with experimental results and suggest that Cyt C does not undergo significant structural disruption

247 The Cyt-CVNH structure and glycan recognition profile are si

248 However, the Q(10) of the Alt and the Cyt pathways (+ADP) increased with increasing UQ(r)/UQ(t

249 aspase-3, -8, or -9 was detected between the Cyt c(T)(-/-) testes and controls.

250 neration sequencing of RNA isolated from the Cyt c-RNP complex reveals that 20 tiRNAs are highly enri

251 e comparison with experimental data, has the Cyt displaced by approximately 10 A from its position in

252 ls that 20 tiRNAs are highly enriched in the Cyt c-RNP complex.

253 he Cyt-1 isoform of ErbB4, and absent in the Cyt-2 isoform.

254 A key component is the Cyt toxin, which synergizes the activity of the other Cr

255 that recognize the p22(phox) subunit of the Cyt b heterodimer.

256 Functionality of the Cyt c glycoconjugates was determined by performing cell-

257 The results show that 95% or more of the Cyt c population folds by stepping down through the same

258 onfirm the sequential stepwise nature of the Cyt c unfolding pathway and therefore a similar refoldin

259 ration before and after self-assembly of the Cyt c.

260 The heme of the Cyt is oriented toward Tyr L162 on the RC, the tunneling

261 re was little difference in the Q(10) of the Cyt pathway with or without ADP; however, the Q(10) of C

262 ystematic structural characterization of the Cyt toxin interaction with different membranes, includin

263 Formation of the Cyt-S4 and 6TG complex of the 2:1 stoichiometry was post

264 y is not less temperature sensitive than the Cyt pathway or COX per se and that changes in the degree

265 rylated, and we have recently shown that the Cyt c electron acceptor COX is phosphorylated on Tyr-304

266 Mechanistic studies suggest that the Cyt c molecules must undergo a significant conformationa

267 Our data indicate that the Cyt c(T)-null testes undergo early atrophy equivalent to

268 ce of the QDs is inversely correlated to the Cyt c concentration.

269 e ErbB4 intracellular domain specific to the Cyt-1 isoform of ErbB4, and absent in the Cyt-2 isoform.

270 Therefore, Cyt-CVNH may qualify as a valuable lectin for potential

271 n extracellular source, copper allocation to Cyt oxidase includes CRR1-dependent proteolysis of plast

272 yl transfer occurs after Cys(1226) attack to Cyt C6, and the methyl transfer step is chemically rate-

273 e energy transfer mechanism from Hb/AuNCs to Cyt c and photoinduced electron transfer from DNA/AgNCs

274 ized, p22(phox)-specific mAb) for binding to Cyt b, supporting phage display results suggesting that

275 te to template 8-oxoG, or 8-oxoG opposite to Cyt.

276 of the copper cofactor from plastocyanin to Cyt oxidase.

277 Increased binding of QDs to Cyt c results in decreasing fluorescence.

278 ansfer from S-adenosyl-l-methionine (SAM) to Cyt C5, and proton abstraction from C5 to form methylate

279 2.5 microM for alkaline phosphatase-treated Cyt c.

280 rocytes did not exhibit Asc-reducible b-type Cyt activity.

281 te membranes contain an Asc-reducible b-type Cyt having the same spectral characteristics as recombin

282 this protein encodes an ASC-reducible b-type Cyt with absorbance characteristics similar to that of o

283 TO fractions contain an ASC-reducible b-type Cyt with alpha-band absorbance maximum near 561 nm.

284 addition, motile, granule-poor cytoplasts (U-Cyt) from human blood PMN can exert anti-Borrelia activi

285 Here we show that lysates of U-Cyt also possess anti-Borrelia activity, a portion of wh

286 The anti-Borrelia activity of U-Cyt lysates and recombinant calprotectin was partially o

287 s of temperature and denaturant which unfold Cyt c but do not alter the thermophilic proteasome, Cyt

288 cleavage products established that unfolded Cyt c and its covalently attached heme prosthetic group

289 ogether, these results suggest a model where Cyt c' in R. sphaeroides 2.4.3 may shuttle NO to the mem

290 nally similar to the wild-type cytosolic (WT Cyt) allozyme, whereas the R424C and S457F cytosolic var

291 Interestingly, the WT Cyt c(551), but not the mutant form, significantly enhan

292 thotrexate and pemetrexed relative to the WT Cyt form of FPGS.

293 cytosolic variants when compared with the WT Cyt isoform.

294 -fold in protein expression compared with WT Cyt (P < 0.01).

295 ng activity in macrophages, compared with WT Cyt c(551).

296 2.6-fold (S457F, P < 0.01) compared with WT Cyt.

297 We first applied X-Cyt to quantify CD4(+) effector and central memory T cel

298 devised an automated, user-guided method, X-Cyt, which specializes in rapidly and robustly identifyi

299 fine-tuning effect is abolished in the Y67F Cyt mutant, which presents a lambda value similar to the

300 Starting with the yeast Cyt c plus heme lyase construct of Pollock et al., an E.