ライフサイエンスコーパス: D-amino-acid oxidase

1 of five structurally distinct inhibitors of d-amino acid oxidase.

2 relatives of ThiO are sarcosine oxidase and d-amino acid oxidase.

3 ttached flavin analogue in recombinant human d-amino acid oxidase.

4 ctral changes similar to those observed with d-amino acid oxidase.

5 mic FAD-dependent oxidoreductases related to d-amino acid oxidases.

6 ed by exposure to H(2)O(2) or D-alanine plus D-amino acid oxidase (40 U/mL).

7 r genes, disrupted in schizophrenia (DISC1), D-amino acid oxidase activator (DAOA), regulator of G-pr

8 Studies to date have implicated the D-amino acid oxidase activator complex (also known as G7

9 renia 1 (DISC1), D-amino-acid oxidase (DAO), D-amino-acid oxidase activator (DAOA, formerly known as

10 We suggest that the perturbation of the D-amino acid oxidase active site is due to the nonpolar

11 as pharmacological inhibition of endogenous D-amino acid oxidase activity revealed that D-serine is

12 Selective degradation of D-serine by D-amino acid oxidase and pharmacologic inhibition of SR

13 iated by the FDA-approved drug auranofin and D-amino acid oxidase as an effective antiviral strategy

14 ofile bacterial d-AA production, combining a d-amino acid oxidase-based enzymatic assay for rapid ass

15 ontrast to the case of CH(3)CCl=NO(2)(-) and D-amino acid oxidase) because, in the enzyme-substrate e

16 tein active site and acts efficiently during d-amino acid oxidase catalytic turnover.

17 Using D-amino acid oxidase coupled with catalase for the deami

18 with the glycine oxidase-N-acetylglycine and d-amino acid oxidase-d-alanine complexes demonstrate tha

19 The D-AA with the class enzyme D amino acid oxidase (DAAO) generates H2O2.

20 separation and the specific reaction between D-amino acid oxidase (DAAO) and each D-AA biomarker avoi

21 A comparison with d-amino acid oxidase (DAAO) demonstrates that both enzym

22 because of the difference in expression of a D-amino acid oxidase (DAAO) enzyme between Schwann cells

23 etic transgenic mouse lines expressing yeast D-amino acid oxidase (DAAO) in neurons and vascular endo

24 Luvadaxistat, a D-amino acid oxidase (DAAO) inhibitor that increases the

25 ntermediate that accumulates in reactions of D-amino acid oxidase (DAAO) with alanine.

26 We have investigated the interaction of d-amino acid oxidase (DAAO) with single-walled carbon na

27 erivatives were synthesized as inhibitors of D-amino acid oxidase (DAAO).

28 o be due to D-serine undergoing oxidation by D-amino-acid oxidase (DAAO) before it reaches the brain.

29 in the protein framework of the flavoprotein D-amino-acid oxidase (DAAO).

30 flavin adenine dinucleotide (FAD) -dependent d-amino acid oxidase (DAAOx), based on the monitoring of

31 ing the rapid dispersion of the class-enzyme D-amino acid oxidase (DAO) and L-amino acid oxidase (LAO

32 ermore, the microbiota induces production of d-amino acid oxidase (DAO) by intestinal epithelial cell

33 yotrophic lateral sclerosis (ALS)-associated D-amino acid oxidase (DAO) that reduces D-serine metabol

34 One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes t

35 by serine racemase and is metabolized by the D-amino acid oxidase (DAO, DAAO).

36 und for the D-serine plasma-CSF ratio at the D-amino-acid oxidase (DAO) gene (beta=-0.28; P=9.08 x 10

37 genes, disrupted in schizophrenia 1 (DISC1), D-amino-acid oxidase (DAO), D-amino-acid oxidase activat

38 expression of the d-serine degrading enzyme d-amino acid oxidase (Dao1) in the hippocampus of cocain

39 anner attenuated by scavenging D-serine with D-amino acid oxidase, deleting the enzyme responsible fo

40 loning and expression of a dao gene encoding D-amino acid oxidase from Schizosaccharomyces pombe in t

41 that selective degradation of d-serine with D-amino acid oxidase greatly attenuates NMDA receptor-me

42 ine transport inhibitor, and luvadaxistat, a D-amino acid oxidase inhibitor that increases brain D-se

43 e by prolonged treatment with d-serine and a d-amino acid oxidase inhibitor.

44 In contrast, incubation of D-amino acid oxidase or nitroalkane oxidase with 2-oxo-3

45 of histidine 307 with leucine in pig kidney D-amino acid oxidase perturbs its active site conformati

46 nylenediamine (PPD) layer and an R. gracilis D-amino acid oxidase (RgDAAO) layer.

47 2)O(2)-producing enzyme Rhodotorula gracilis D-amino acid oxidase (rgDAAO) selectively in astrocytes.

48 gic targets, including glycine transporters, D-amino acid oxidase, sodium channels, or potassium chan

49 erine peak was confirmed unambiguously using D-amino acid oxidase to selectively remove D-serine from

50 n the photoreduction of the non-photosensory d-amino acid oxidase to the anion radical.

51 Treatment with D-amino acid oxidase, which breaks down D-amino acids pr

52 Application of d-amino acid oxidase, which degrades d-serine, reduced t