ライフサイエンスコーパス: D-ribose

1 duced from respective d-isoascorbic acid and d-ribose.

2 ted binding specificity for myo-inositol and D-ribose.

3 s were accomplished in 24 steps from 2-deoxy-D-ribose.

4 nate, N-acetyl-D-glucosamine, D-mannose, and D-ribose.

5 ere both stereospecifically synthesized from D-ribose.

6 nthesized starting from tribenzoyl protected d-ribose.

7 rise from D-GlcNAc and 1 from uridine and/or D-ribose.

8 ized on EAH-Sepharose gel and glycated using d-ribose.

9 clic phosphate that might be found on a beta-D-ribose.

10 hieved by modifying reported procedures from D-(-)-ribose.

11 Instead, MTA is converted to 5-methylthio-d-ribose 1-phosphate (MTR 1-P) and adenine; MTR 1-P is i

12 e 5-phosphate (ribose 5-phosphate) and alpha-D-ribose 1-phosphate (ribose 1-phosphate).

13 ized forms is expected to apply to D-ribose, D-ribose 1-phosphate, ribonucleosides, and ribonucleotid

14 orolysis of thymidine to thymine and 2-deoxy-D-ribose 1-phosphate.

15 in a radical-based reaction producing alpha-D-ribose-1,2-cyclic-phosphate-5-phosphate and methane in

16 phoryl-5-phosphoribose via a 5-phospho-alpha-d-ribose-1-diphosphate:decaprenyl-phosphate 5-phospho-ri

17 The Rv3806c gene encoding 5-phospho-alpha-d-ribose-1-diphosphate:decaprenyl-phosphate 5-phosphorib

18 nTP is hydrolysed to pyrophosphate and alpha-D-ribose-1-methylphosphonate-5-phosphate (PRPn).

19 lphosphonate reacts with MgATP to form alpha-D-ribose-1-methylphosphonate-5-triphosphate (RPnTP) and

20 Methylthio-d-ribose-1-phosphate (MTR1P) isomerase (MtnA), which fun

21 ase; (iii) LipM, a UTP:5-amino-5-deoxy-alpha-D-ribose-1-phosphate uridylyltransferase; and (iv) LipN,

22 e adenosine + phosphate <--> adenine + alpha-D-ribose-1-phosphate.

23 ed pathway for RuBP synthesis from 5-phospho-D-ribose-1-pyrophosphate (PRPP) in M. jannaschii and oth

24 sitionally labeled [(13)C]-D-Glc and [(13)C]-D-ribose ([(13)C]-D-Rib) precursors and a novel derivati

25 cide inhibition of decaprenylphosphoryl-beta-D-ribose 2' oxidase (DprE1), which is responsible for ce

26 st AQs, identified decaprenylphosphoryl-beta-d-ribose 2'-epimerase (DprE1) as the primary target resp

27 Decaprenylphosphoryl-beta-d-ribose 2'-epimerase (DprE1) is an essential enzyme in

28 to 14 by mutating decaprenylphosphoryl-beta-d-ribose 2-oxidase (DprE1), an essential enzyme in arabi

29 olopyridones to be decaprenylphosphoryl-beta-D-ribose-2'-epimerase (DprE1).

30 lent inhibition of decaprenylphosphoryl-beta-d-ribose-2'-epimerase (DprE1).

31 prE1, a subunit of decaprenylphosphoryl-beta-d-ribose-2'-epimerase.

32 on a 10 g scale with 52% overall yield from D-ribose (4).

33 p-Nitrophenyl beta-D-ribose 5'-phosphate is a poor substrate of PfOPRT and

34 (2dR5P), as an alternate substrate, but not D-ribose 5-phosphate (R5P) nor the four carbon analogue

35 superfamily members that interconvert alpha-D-ribose 5-phosphate (ribose 5-phosphate) and alpha-D-ri

36 A. mediterranei cell-free lysate along with D-ribose 5-phosphate and phosphoenolpyruvate.

37 oheptulose 7-phosphate as the C(3) donor and D-ribose 5-phosphate as the C(5) acceptor.

38 y is derived from D-fructose 6-phosphate and D-ribose 5-phosphate via a transaldol reaction catalyzed

39 This shows that Delta(f)G degrees (2'-deoxy-D-ribose 5-phosphate(2)(-)) - Delta(f)G degrees (D-ribos

40 bose 5-phosphate(2)(-)) - Delta(f)G degrees (D-ribose 5-phosphate(2)(-)) = 147.86 kJ mol(-1) at 298.1

41 7-phosphate) and nucleotide metabolism (via D-ribose 5-phosphate) was associated with perturbations

42 ccharide analogues, D-arabinose 5-phosphate, D-ribose 5-phosphate, and 2-deoxy-D-ribose 5-phosphate,

43 phosphate, D-ribose 5-phosphate, and 2-deoxy-D-ribose 5-phosphate, were separately condensed with (Z)

44 (f)G degrees for D-ribose and two species of D-ribose 5-phosphate.

45 grees for two protonation states of 2'-deoxy-D-ribose 5-phosphate.

46 mples of an alternate substrate derived from d-ribose (5-OH group instead of the 5-methylthio group i

47 rected evolution of Escherichia coli 2-deoxy-d-ribose-5-phosphate aldolase (EcDERA), we developed an

48 conceivably through Michael-type addition of d-ribose-5-phosphate and dephosphorylation.

49 The crystal structure of the complex with D-ribose-5-phosphate indicated that the phosphosugar is

50 Recently, we have identified the D-ribose-5-phosphate origin of the dioxane unit and demo

51 osynthase, which catalyzes the attachment of D-ribose-5-phosphate to prealnumycin by formation of the

52 ity of 6-PG for oxidative decarboxylation to D-ribose-5-phosphate, which is essential for the utiliza

53 To determine the roles of L-fucose and D-ribose, an E. coli MG1655 DeltafucAO mutant and an E.

54 olefination reaction with 2,3,5-tri-O-benzyl-D-ribose and -D-arabinose.

55 x 10(-2) M, as indicated by the Ki values of D-ribose and 1-methyl-D-ribofuranoside as competitive in

56 nown life is the utilization of right-handed d-ribose and d-deoxyribose sugars and left-handed l-amin

57 e demonstrate that both membranes select for d-ribose and d-deoxyribose sugars while the hybrid membr

58 initol, starting from commercially available D-ribose and D-lyxose was tested out.

59 G degrees values for the species of 2'-deoxy-D-ribose and its derivatives makes it possible to calcul

60 , we synthesized a variety of C4'-methylated d-ribose and l-lyxose-configured uridine derivatives by

61 The presence of D-ribose and nosturonic acid as peripheral groups is unu

62 aw heat capacity measurements on crystals of d-ribose and other calorimetric measurements make it pos

63 possible to calculate Delta(f)G degrees for D-ribose and two species of D-ribose 5-phosphate.

64 r pattern of endothelial plasticity: 2-deoxy-d-ribose and VEGFA produce transcriptional programs enco

65 d Q building blocks 9 (obtained from 2-deoxy-D-ribose) and 10 (obtained from D-ribose) followed by ri

66 o produce acid from carbohydrates other than D-ribose, and were biochemically and enzymatically fairl

67 wo distinct ligands, fructose (anti-FruR) or D-ribose (anti-RbsR); and were complemented by 14 additi

68 ding allele affected C. crescentus growth on D-ribose as a carbon source, providing evidence that the

69 lly available 8-hydroxyquinaline and 2-deoxy-d-ribose as key starting materials.

70 ficient to increase the affinity of IbpA for D-ribose by 10-fold while completely abolishing binding

71 owed that L-fucose stimulated utilization of D-ribose by the E. coli MG1655 DeltafucAO mutant but not

72 e populations of Escherichia coli B all lost D-ribose catabolic function during 2,000 generations of

73 al cells, VEGFA and the TYMP product 2-deoxy-d-ribose cooperatively repress tight junction proteins,

74 d and oxidized forms is expected to apply to D-ribose, D-ribose 1-phosphate, ribonucleosides, and rib

75 de novo preparation of L-ribulose, L-lyxose, D-ribose, D-tagatose, 1-amino-1-deoxy-D-lyxitol, and oth

76 nines or an N(2)-alkyl-6-chloroguanine and a D-ribose derivative containing a 2-ethyltetrazolyl moiet

77 s achieved in 10 steps starting from a known d-ribose derivative.

78 ppropriate 5-O-alkyl-1,2,3-tri-O-acetyl-beta-D-ribose derivatives with 2,5,6-trichlorobenzimidazole f

79 eoisomer (39%) for further coupling with the d-ribose-derived 5-alcohol.

80 The use of a d-ribose-derived lithiated dithiane nucleophile in this

81 from 2-deoxy-D-ribose) and 10 (obtained from D-ribose) followed by ring-closing metathesis to afford

82 Incubation with 500 and 100 mm d-ribose for 2 and 15 days produced short-term glycated

83 ns it could have been formed from homochiral D ribose from the hydrolysis of amplified adenosine or c

84 rmediate 11b was synthesized in 4 steps from d-ribose in 41% overall yield via an efficient intramole

85 via a ring-closing metathesis reaction from d-ribose in eight steps.

86 flavour enhancer solution (FES) (d-glucose, d-ribose, l-cysteine and thiamin) and of sous-vide cooki

87 when it was exposed to D-mannose, D-fucose, D-ribose, L-glucose, or L-galactose, but it changed mark

88 h the alternative substrates D-erythrose and D-ribose, making SalM the first reported stereospecific

89 ionine salvage pathway in which 5-methylthio-d-ribose (MTR) derived from 5'-methylthioadenosine is co

90 "L-cIDPR", the natural "northern" N1-linked D-ribose of cADPR was replaced by L-ribose.

91 the geometry of sugars referred to D, as in D-ribose or D-glucose, is not an independent mystery.

92 tion to low folAmix by rerouting the 2-Deoxy-D-ribose-phosphate metabolism from glycolysis towards sy

93 yranoside stereochemistry, from d-lyxose and d-ribose precursors.

94 r pyrophosphate to form phosphorylated alpha-D-ribose products.

95 were prepared from D-gamma-ribonolactone and D-ribose, respectively.

96 was predetermined by the prior evolution of D-ribose RNA and probably was chirally directed by the o

97 ock is also presented: Starting from 2-deoxy-d-ribose, the optimized sequence now makes the use of th

98 Starting from 2-deoxy-d-ribose, the product is obtained in a 6.7% overall yiel

99 In turn, myeloma cell-secreted 2-deoxy-D-ribose, the product of thymidine catalyzed by the func

100 visualize the oxidation of 5-chloro-5-deoxy-D-ribose to 5-chloro-5-deoxy-D-ribono-gamma-lactone in a

101 D-ribose was transformed into methanocarba alcohol 3 fol

102 at of the related lipid, polyprenylphosphate-D-ribose, was investigated.

103 tricyclic core is derived from d-glucose and d-ribose, whereas the tiglyl moiety is derived from an i

104 olved reactions of d-xylose, d-arabinose and d-ribose with glycine, alpha-l- or beta-alanine and l-va

105 ologous to ribose-binding proteins and binds D-ribose with low affinity (50.8 +/- 3.4 muM).