ライフサイエンスコーパス: DNA repair enzyme

1 inhibition of poly(ADP-ribose) polymerase, a DNA repair enzyme.

2 dsDNA, implicating it as a flavin-dependent DNA repair enzyme.

3 Escherichia coli exonuclease III (ExoIII), a DNA repair enzyme.

4 ctions in alkylated base recognition by this DNA repair enzyme.

5 ts resembles the ATP-bound form of the Rad50 DNA repair enzyme.

6 ic endonuclease 1 (Ape1), the major oxidized DNA repair enzyme.

7 ocated upstream of recG, encoding a putative DNA repair enzyme.

8 Thus, it may be a versatile DNA repair enzyme.

9 steps involved in damage recognition by this DNA repair enzyme.

10 ified reaction mechanism for this intriguing DNA repair enzyme.

11 eveals that PE exemplifies a unique class of DNA repair enzyme.

12 may function as a general 3'-end-processing DNA repair enzyme.

13 ter base pairing and their interactions with DNA repair enzymes.

14 mage repair via interaction with a number of DNA repair enzymes.

15 mising after possible down-regulation of the DNA repair enzymes.

16 ation and excision of damaged nucleobases by DNA repair enzymes.

17 about the impact of higher order folding on DNA repair enzymes.

18 y which Chk2 protein regulates expression of DNA repair enzymes.

19 hrough the relation between nitric oxide and DNA repair enzymes.

20 A backbone distortion and may be targeted by DNA repair enzymes.

21 homologous to the helix-hairpin-helix (HhH) DNA repair enzymes.

22 belonging to the endonuclease III family of DNA repair enzymes.

23 he base excision repair (BER) superfamily of DNA repair enzymes.

24 . maritima UDG is a member of a new class of DNA repair enzymes.

25 s a member of the endonuclease III family of DNA repair enzymes.

26 nto a variety of proteins, including several DNA repair enzymes.

27 ntially trigger reversion of the mutation by DNA repair enzymes.

28 e cells to cope with DNA damage by utilizing DNA repair enzymes.

29 irpin-helix DNA-binding motif found in other DNA repair enzymes.

30 cDNA, and thereby prime it for processing by DNA repair enzymes.

31 ating intermediates may be a common theme in DNA repair enzymes.

32 e presents one of the greatest challenges to DNA repair enzymes.

33 ing helicases, polymerases, recombinases and DNA repair enzymes.

34 from photolyases, bacterial light-activated DNA repair enzymes.

35 y the tumor mutational burden and defects in DNA repair enzymes.

36 A that may serve as a recognition signal for DNA repair enzymes.

37 th factor receptor (EGFR) overexpression and DNA repair enzymes.

38 and demonstrate this method using the human DNA repair enzyme 3-methyladenine DNA glycosylase (AAG).

39 nks inflammation in UC with increases in the DNA repair enzymes 3-methyladenine DNA glycosylase and a

40 n and identification of VPg unlinkase as the DNA repair enzyme, 5'-tyrosyl-DNA phosphodiesterase-2 (T

41 Unlike the homologous DNA repair enzyme 6-4 PHOTOLYASE, CRYs have extended car

42 sine (oxo8dG) levels and the activity of the DNA repair enzyme 8-oxoguanine DNA glycosylase (Ogg1) in

43 breast cancer by genetically modulating the DNA repair enzyme 8-oxoguanine DNA glycosylase (OGG1) in

44 lated to genes in bacteria and yeast for the DNA repair enzyme 8-oxoguanine DNA glycosylase.

45 Using histone demethylase JMJD1A and DNA repair enzyme ABH2 as examples, we show that this fa

46 ed aptamer selection to a medically relevant DNA repair enzyme, ABH2.

47 al mechanism to coordinate the activities of DNA repair enzymes across the genome.

48 action of a DNA recombinase and, once bound, DNA repair enzymes act to excise the nucleotide, replace

49 Direct measurement of DNA repair enzyme activities is important both for the b

50 be extended for analysis of a wide range of DNA repair enzyme activities.

51 molysin protein nanopore was used to monitor DNA repair enzyme activity based on base-specific intera

52 The Escherichia coli DNA repair enzyme AlkB is a 2-oxoglutarate (2OG)-depende

53 umans express nine paralogs of the bacterial DNA repair enzyme AlkB, an iron/2-oxoglutarate-dependent

54 op a quantitative mechanistic scheme for the DNA repair enzyme AlkB.

55 erted into a substrate (ZP1BG) for the human DNA repair enzyme alkylguaninetransferase (AGT or SNAP-T

56 lonC), are released from DNA in vitro by the DNA repair enzyme alkylpurine-DNA-N-glycosylase (APNG).

57 The use of an inhibitor of a DNA repair enzyme alone to selectively kill a tumour, in

58 incorporation of HIF-1 and the bi-functional DNA repair enzyme and transcriptional coactivator, Ref-1

59 AF1) E3 to antagonize select postreplication DNA repair enzymes and activates the DNA damage checkpoi

60 shed light on the interplay between central DNA repair enzymes and an essential molecular chaperone.

61 ion Factor for DNA (DNA-SPF), using specific DNA repair enzymes and antibodies, and Sun Protection Fa

62 ules, alone and in complexes with a suite of DNA repair enzymes and antibodies, to directly quantify

63 l terminus) domains are found in a number of DNA repair enzymes and cell cycle regulators and are bel

64 Because BLBC exhibits alterations in DNA repair enzymes and cell-cycle checkpoints, elucidati

65 ural insights into metal inhibition of other DNA repair enzymes and glycosylases.

66 vergent interactions of HIV-1 and HIV-2 with DNA repair enzymes and SAMHD1 imply that these viruses u

67 ) for repairing molecular damage by means of DNA-repair enzymes and protein-repair enzymes such as me

68 he first such example of the regulation of a DNA repair enzyme, and identify a novel function of hnRN

69 activation-induced cytidine deaminase (AID), DNA repair enzymes, and post-class-switch expression of

70 zinc deficiency on DNA damage, expression of DNA-repair enzymes, and downstream signaling events in a

71 lation of the dual function reducing protein/DNA repair enzyme APE/redox factor-1(ref-1).

72 of the abasic site in the recognition by the DNA repair enzyme Ape1 is discussed.

73 Besides its prominent role as a DNA repair enzyme, APE1 was separately identified as a p

74 ges, there were progressive increases in the DNA repair enzyme APEX1, the cell cycle control proteins

75 ed expression of the essential base excision DNA repair enzyme apurinic endonuclease 1 (Ape1) in resp

76 glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I p

77 w here that crocidolite asbestos induces the DNA repair enzyme, apurinic/apyrimidinic (AP)-endonuclea

78 Two other DNA repair enzymes are known to repair epsilon-base lesi

79 ts of this lesion and the various adducts on DNA repair enzymes are unknown, but their facile generat

80 (transposases, recombinases, integrases and DNA repair enzymes) are being harnessed or modified for

81 olymerase mu (pol mu) is a novel error-prone DNA repair enzyme bearing significant structural homolog

82 mu2 does not code for a DNA repair enzyme because mu2 mutants are not hypersensi

83 seq are (i) low false-positive rates because DNA repair enzyme binding is required for genome edits t

84 east cancer 1 early onset gene codes for the DNA repair enzyme, breast cancer type 1 susceptibility p

85 t are highly homologous to photoreactivating DNA repair enzymes but that function as blue light photo

86 ulted in the co-evolution of DNMTs and ALKB2 DNA repair enzymes, but its mechanism remained elusive.

87 n-sulfur cluster in DinG and likely in other DNA repair enzymes by NO may contribute to NO-mediated g

88 We investigated whether two human DNA repair enzymes can mediate OAS excision in vitro: Ap

89 c phenotype, such that animals lacking all 3 DNA repair enzymes cannot survive even a single bout of

90 tranded lesions affects their recognition by DNA repair enzymes, clustered damages are more difficult

91 It has been widely assumed that host DNA repair enzymes complete attachment of the remaining

92 Surprisingly, deficiency in all 3 DNA repair enzymes confers a massively synergistic pheno

93 An array of DNA-repair enzymes constitutes an essential part of the

94 An 8-OG:G mispair, if not corrected by DNA repair enzymes, could lead to G:C to C:G transversio

95 Cleavage assays with lesion-specific DNA repair enzymes coupled to ligation-mediated PCR show

96 e protein TP53I3, transcription factor ATF3, DNA repair enzyme DDB2, and the beta-adrenergic receptor

97 cent structures of the R283K mutant of human DNA repair enzyme DNA polymerase beta (pol beta) differi

98 We identified two promising genes in the DNA repair enzyme DNA polymerase beta and in the neuroen

99 valuated for inhibitory activity against the DNA repair enzyme DNA-dependent protein kinase (DNA-PK),

100 The DNA repair enzyme, DNA polymerase beta (Pol beta), is am

101 Only two DNA repair enzymes, DNA polymerase beta and O6-methylgua

102 ered Fe-S incorporation into MMS19-dependent DNA repair enzymes, DNA repair capacity, sensitivity to

103 mations of macromolecular substrates such as DNA repair enzyme/DNA transformations are commonly inter

104 onucleases (e.g., T7 gene 6 exonuclease) and DNA repair enzymes (e.g., uracil-DNA glycosylase).

105 solated and probed with the Escherichia coli DNA repair enzyme endonuclease IV (endo IV), which recog

106 ology with the [4Fe-4S]2+ cluster-containing DNA repair enzyme, endonuclease III.

107 lished; these adducts are readily excised by DNA repair enzymes engaged in nucleotide excision repair

108 y of intramolecular electron transfer in the DNA-repair enzyme, Escherichia coli photolyase, a protei

109 l binding protein-interacting protein (CtIP) DNA repair enzyme, establishing a role for CtIP in regul

110 such as temozolomide lose their efficacy if DNA repair enzyme expression is upregulated.

111 unctionally significant differences exist in DNA repair enzyme extrahelical nucleotide binding and ca

112 Oligonucleotide purity is assayed using the DNA repair enzyme formamidopyrimidine DNA glycosylase an

113 uplex DNA substrates by the Escherichia coli DNA repair enzyme Fpg.

114 The Escherichia coli DNA repair enzymes Fpg and MutY are involved in the prev

115 on of DNA with histones in chromatin impedes DNA repair enzymes from accessing DNA lesions.

116 showed additional functional similarities to DNA repair enzymes from other organisms.

117 A DNA repair enzyme has recently been isolated from the io

118 steps, thought to be carried out by cellular DNA repair enzymes, have not been fully characterized.

119 Targeting the DNA repair enzyme human 8-oxoguanine DNA glycosylase (hO

120 xpression vector containing the gene for the DNA repair enzyme human 8-oxoguanine DNA glycosylase/apu

121 The DNA repair enzyme human uracil DNA glycosylase (UNG) sca

122 hemotherapeutics as inhibitors of a critical DNA repair enzyme, human AP endonuclease.

123 lymerase lambda (pol lambda), a low-fidelity DNA repair enzyme in the X-family that fills short nucle

124 The presence of multiple versions of DNA repair enzymes in a single organism is usually thoug

125 of chromatin, which presents a challenge to DNA repair enzymes in that recognition, incision, and re

126 ss of alpha-KG/Fe(II)-dependent proteins-the DNA repair enzymes in the AlkB family, which include ALK

127 ed a track that allows long-range sliding of DNA repair enzymes in their search for rare damage sites

128 Analysis of the involvement of DNA repair enzymes in trimethoprim-induced cytotoxicity

129 mal looping in CSR, and the roles of certain DNA-repair enzymes in CSR.

130 of tyrosyl-DNA-phosphodiesterase 1 (TDP1), a DNA repair enzyme, in ATL cells.

131 Maladaptive processing of the DNA damage by DNA repair enzymes, in particular by MutM and MutY DNA g

132 lesions are further processed by downstream DNA "repair" enzymes including error-prone translesion p

133 racteristic of the endonuclease IV family of DNA repair enzymes, including apurinic/apyrimidinic endo

134 Because many DNA methyltransferases and DNA repair enzymes induce similar DNA distortions, these

135 Therefore, targeting DNA repair enzymes into beta-cell mitochondria could be

136 an apurinic/apyrimidinic endonuclease 1 is a DNA repair enzyme involved in genome stability and expre

137 The promiscuity of DNA repair enzymes is particularly important, because it

138 A hallmark of these and other DNA repair enzymes is their use of base flipping to sequ

139 Poly(ADP-ribose) polymerase-1 (PARP-1), a DNA repair enzyme, is involved in the induction of necro

140 ylpurine-DNA glycosylase (MPG), a ubiquitous DNA repair enzyme, is responsible for the removal of a w

141 proteolytic processing of PARP (the nuclear DNA repair enzyme known to be cleaved in association wit

142 lyase is unique in being the first and only DNA repair enzyme known to function via this novel enzym

143 nes induce iNOS and sufficient NO to inhibit DNA repair enzymes leading to the development and progre

144 phosphoesterase (PE) domain of the bacterial DNA repair enzyme LigD possesses distinctive manganese-d

145 We also found evidence that a DNA repair enzyme may play a role in modifying the seque

146 Thus, induction of DNA repair enzymes may be a unique strategy for neuropro

147 l extracts and COX activity, suggesting that DNA repair enzymes may be regulated by a mechanism diffe

148 NO inactivation of DNA repair enzymes may provide a link between inflammati

149 Mutant forms of the DNA repair-enzyme methylguanine methyltransferase in par

150 chemoprotection mediated by a mutant of the DNA-repair enzyme methylguanine methyltransferase could

151 Eukaryotic DNA repair enzymes must interact with the architectural

152 leases as well as lambda-exonuclease and the DNA repair enzymes MutH and Vsr, implying a common evolu

153 ne kinases with class II topoisomerases, the DNA repair enzyme MutL and the molecular chaperone Hsp90

154 and structurally elucidated a base-excision DNA repair enzyme, MutM, at the stage of initial encount

155 uces oxidative DNA damage, expression of the DNA repair enzyme MutS2, and mutations in cagY, demonstr

156 The DNA repair enzyme MutY plays an important role in the pr

157 The Escherichia coli DNA repair enzyme MutY plays an important role in the pr

158 The DNA repair enzyme MutY plays an important role in the pr

159 The Escherichia coli DNA repair enzyme MutY plays an important role in the re

160 The Escherichia coli DNA repair enzyme MutY plays an important role in the re

161 The Escherichia coli DNA repair enzyme MutY plays an important role in the re

162 Control of the N-glycosylase reaction by the DNA repair enzyme, MutY, entails the organization of sol

163 Higher expression of the human DNA repair enzyme MUTYH has previously been shown to be

164 Editing of the pre-mRNA for the DNA repair enzyme NEIL1 causes a lysine to arginine chan

165 The DNA repair enzyme NEIL1 is a DNA glycosylase that is inv

166 The DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase

167 ified using a lentiviral vector encoding the DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase

168 emozolomide; however, gliomas expressing the DNA repair enzyme O(6)-methylguanine-DNA methyltransfera

169 lesion is removed in the normal cell by the DNA repair enzyme O(6)-methylguanine-DNA methyltransfera

170 Expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransfera

171 stance gene, such as the P140K mutant of the DNA repair enzyme O6-methylguanine-DNA methyltransferase

172 The DNA repair enzyme O6-methylguanine-DNA methyltransferase

173 The DNA-repair enzyme O6-methylguanine-DNA methyltransferase

174 let damage endonuclease (UVDE) is a 68.7 kDa DNA repair enzyme of Schizosaccharomyces pombe that reco

175 ic/apyrimidinic endonuclease (APE) family of DNA-repair enzymes of the DNase-I superfamily.

176 e product 8-oxoG and increased levels of the DNA repair enzyme OGG-1.

177 of uracil DNA glycosylase (UNG2), a cellular DNA repair enzyme, on the virus mutation rate and on rep

178 How DNA repair enzymes or complexes gain access to chromatin

179 osomes over DNA, the ionic dependence of the DNA repair enzyme PARP1 in DNA binding, and the interact

180 The DNA repair enzyme photolyase provides a natural system t

181 f sequence identity with the light-activated DNA repair enzyme photolyase.

182 ly conserved and structurally related to the DNA repair enzyme photolyase.

183 The same is also true for the DNA repair enzyme, photolyase.

184 ase caspase 3 and subsequent cleavage of the DNA repair enzyme poly (adenosine diphosphate [ADP]-ribo

185 nd subsequent cleavage of its substrate, the DNA repair enzyme poly (ADP-ribose) polymerase.

186 thelial cells, which, in turn, activates the DNA repair enzyme poly(ADP)-ribose polymerase.

187 tly labelled small-molecule inhibitor of the DNA repair enzyme poly(ADP-ribose) polymerase 1 (PARP1)

188 Inhibition of the DNA repair enzyme poly(ADP-ribose) polymerase 1 (PARP1)

189 appears to be mediated by activation of the DNA repair enzyme poly(ADP-ribose) polymerase and subseq

190 Activation of caspase-3 and the cleavage of DNA repair enzyme poly(ADP-ribose) polymerase were inhib

191 ting of DNA damage, excess activation of the DNA repair enzyme poly(ADP-ribose) polymerase, and deple

192 Inhibition of the DNA repair enzyme poly(ADP-ribose) polymerase-1 (PARP-1)

193 otinamide (1 mmol/L each), inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase.

194 l models, possibly through inhibition of the DNA repair enzyme poly-ADP-ribose polymerase and prevent

195 and correlated with the inactivation of the DNA-repair enzyme poly(ADP-ribose) polymerase.

196 optotic enzyme caspase-3 and cleavage of the DNA-repairing enzyme poly-(ADP-ribose) polymerase.

197 Annexin V binding, the inactivation of the DNA repair enzyme, poly(ADP-ribose) polymerase, and the

198 the caspase inhibitors, an inhibitor of the DNA repair enzyme, poly(ADP-ribose) polymerase, conferre

199 This may be due to the activation of the DNA repair enzyme, poly(ADP-ribose) polymerase, in respo

200 -1(-/-) mice with targeted disruption of the DNA repair enzyme, poly(ADP-ribose) polymerase.

201 biquitinating activity regulate the cellular DNA repair enzyme polymerase eta and recruit it to poten

202 The DNA-repair enzyme, polymerase beta, was induced in the s

203 ymerase II subunit A (POLR2A), ataxin-3, the DNA repair enzyme polynucleotide-kinase-3'-phosphatase (

204 The dual function mammalian DNA repair enzyme, polynucleotide kinase (PNK), facilita

205 minase (AID) and is completed by error-prone DNA repair enzyme processing of AID-generated uracils.

206 ggest that Cry1 and Cry2, which evolved from DNA repair enzymes, protect genomic integrity via coordi

207 and two nonmembrane-bound ABC proteins, the DNA repair enzyme Rad50 and a structural maintenance of

208 X (a marker of double-strand breaks) and the DNA-repair enzyme RAD51.

209 lained by the impaired recruitment of a core DNA repair enzyme, RAD51, to replication-induced DNA dam

210 are strikingly reminiscent of one subset of DNA-repair enzymes, raising important mechanistic and dr

211 DNA repair enzymes recognize and remove damaged bases th

212 The process by which DNA repair enzymes recognize and selectively excise dama

213 The co-transcription factor and DNA repair enzyme, Redox effector factor-1/apurinic/apyr

214 radation enzymes, restriction endonucleases, DNA-repair enzymes, resolvases, intron splicing factors

215 transferase, thioredoxin, glutaredoxins, and DNA repair enzymes responded most strongly to cadmium an

216 ogically and biomedically important group of DNA repair enzymes responsible for initiating base excis

217 roxynitrite, or that nitric oxide inhibits a DNA repair enzyme(s), leading to an increase in mutation

218 versed to two intact thymines in situ by the DNA repair enzyme SP lyase, an S-adenosylmethionine (S-A

219 versal of SP during spore germination by the DNA repair enzyme SP lyase.

220 haromyces pombe was initially described as a DNA repair enzyme specific for the repair of UV light-in

221 DNA repair enzymes such as human uracil-DNA glycosylase

222 rple acid phosphatases, 5'-nucleotidase, and DNA repair enzymes such as Mre11.

223 threonine phosphatases, 5'-nucleotidase, and DNA repair enzymes such as Mre11.

224 in several ubiquitin pathway proteins and in DNA repair enzymes such as Rad23, and they may be involv

225 the "base flipping" phenomenon found in many DNA repair enzymes such as T4 endonuclease V and uracil

226 fth member of the endonuclease III family of DNA repair enzymes, suggesting that the endonuclease III

227 itroimidazole may not be quickly repaired by DNA repair enzyme systems.

228 The bacterial DNA repair enzyme, T4 endonuclease V, delivered intracel

229 The DNA repair enzyme telomerase maintains chromosome stabil

230 less stable and more easily excised by human DNA repair enzymes than those containing the 10R (-) add

231 Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a DNA repair enzyme that acts upon protein-DNA covalent co

232 MutY is an Escherichia coli DNA repair enzyme that binds to 8-oxo-G:A and G:A mismat

233 Tyrosyl-DNA phosphodiesterase (Tdp1) is a DNA repair enzyme that catalyzes the hydrolysis of a pho

234 imidine/8-oxoguanine DNA N-glycosylase) is a DNA repair enzyme that catalyzes the removal of oxidized

235 e of apurinic endonuclease 1 (Ape1), a human DNA repair enzyme that cleaves adjacent to abasic sites

236 ue and a DNA 3' phosphate and functions as a DNA repair enzyme that cleaves stalled topoisomerase I-D

237 3-methyladenine DNA glycosylase I (TAG) is a DNA repair enzyme that excises 3-methyladenine in DNA an

238 Uracil DNA glycosylase (UNG) is a powerful DNA repair enzyme that has been shown to stabilize a gly

239 n abasic endonuclease, Ape1, is an essential DNA repair enzyme that initiates the removal of apurinic

240 es to process poly(ADP-ribose) polymerase, a DNA repair enzyme that is cleaved within minutes of the

241 uracil DNA glycosylase (UNG2) is a cellular DNA repair enzyme that is essential for a number of dive

242 r cross-complementation group 1 (ERCC1) is a DNA repair enzyme that is frequently defective in non-sm

243 hylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that protects cells from carcinogenic

244 Uracil DNA glycosylase (UNG) is an important DNA repair enzyme that recognizes and excises uracil bas

245 rate recognition by Escherichia coli AlkB, a DNA repair enzyme that removes methyl adducts and some l

246 Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that removes peptide fragments linked

247 DNA alkyltransferase (AGT) is a single-cycle DNA repair enzyme that removes pro-mutagenic O(6)-alkylg

248 DNA polymerase (pol) beta is a two-domain DNA repair enzyme that undergoes structural transitions

249 Y is representative of a unique subfamily of DNA repair enzymes that also contain a [4Fe-4S]2+ cluste

250 te significantly to the specificity of other DNA repair enzymes that bind to extrahelical bases.

251 Contrary to many DNA repair enzymes that can directly reject non-target s

252 d 8-oxoGua-37-mer, a result similar to other DNA repair enzymes that catalyze N-glycosylase/AP lyase-

253 a conserved substrate recognition domain in DNA repair enzymes that couples ATP-hydrolysis to remode

254 The Rh-PPO mechanism is reminiscent of DNA repair enzymes that displace mismatched bases, and i

255 ay play an important role in the activity of DNA repair enzymes that initiate base excision by distor

256 role for the ubiquitous [4Fe-4S] clusters in DNA repair enzymes that involves redox chemistry and pro

257 deaminated purine nucleobases are essential DNA repair enzymes that protect the genome, and at the s

258 Genes coding for DNA repair enzymes that recognize 8-oxoguanine have been

259 that recognize nucleobases, including other DNA repair enzymes that recognize other types of extrahe

260 ses is a class of ubiquitous direct reversal DNA repair enzymes that remove alkyl adducts from nucleo

261 nstrate that the method, in conjunction with DNA repair enzymes that remove damaged bases to produce

262 ion by DNA polymerases work in parallel with DNA repair enzymes that remove lesions produced by modif

263 risons with other DNA methyltransferases and DNA repair enzymes that stabilize extrahelical nucleotid

264 GAA.TTC repeat during transcription attract DNA repair enzymes that then facilitate the expansion pr

265 Photolyases are DNA repair enzymes that use energy from blue light to re

266 ne methyltransferase (MGMT), which encodes a DNA-repair enzyme that confers resistance to the combina

267 rs have been observed previously in Nth/MutY DNA repair enzymes, this is the first observation of suc

268 acil and its derivatives in DNA are bound by DNA repair enzymes through hydrogen bonding and pi-pi st

269 FAN1 encodes a DNA repair enzyme, thus implicating abnormalities in DNA

270 Human (h) DNA repair enzyme thymine DNA glycosylase (hTDG) is a ke

271 er knockout or catalytic inactivation of the DNA repair enzyme thymine DNA glycosylase (TDG) leads to

272 ility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks.

273 Therefore, targeting of DNA repair enzymes to mitochondria may be a viable appro

274 The topical application of DNA repair enzymes to sun-damaged skin of patients with

275 We tested the ability of three DNA-repair enzymes to remove lesions from the DNA strand

276 that interacts in a similar manner with the DNA repair enzyme UNG2 and repair factors XPA and RAD52,

277 We have investigated the inhibition of the DNA repair enzyme uracil DNA glycosylase (UDG) by an 11-

278 The DNA repair enzyme uracil DNA glycosylase (UDG) catalyzes

279 The DNA repair enzyme uracil DNA glycosylase (UDG) hydrolyze

280 The DNA repair enzyme uracil DNA glycosylase (UDG) is a powe

281 The DNA repair enzyme uracil DNA glycosylase (UDG) locates u

282 The DNA repair enzyme uracil DNA glycosylase (UDG) pinches t

283 The reaction catalyzed by the DNA repair enzyme uracil DNA glycosylase (UDG) proceeds

284 The DNA repair enzyme uracil DNA glycosylase (UDG) utilizes

285 A classic example is the DNA repair enzyme uracil DNA glycosylase (UDG) which rec

286 h complex along the catalytic pathway of the DNA repair enzyme uracil DNA glycosylase (UDG).

287 The DNA repair enzyme uracil DNA glycosylase catalyzes the f

288 The DNA repair enzyme uracil DNA glycosylase has been crysta

289 herein are for T4 polynucleotide kinase, the DNA repair enzymes uracil-DNA glycosylase (UDG) and form

290 Previous studies used the DNA repair enzyme UvrABC endonuclease in combination wit

291 21 years ago, the DNA Repair Enzyme was declared "Molecule of the Year".

292 nisms underlying cellular expression of this DNA repair enzyme, we focused on the role of a 59-bp enh

293 DNA-dependent PK (DNA-PK) is a DNA repair enzyme, which we previously found played an i

294 hways, mitochondrial proteins, histones, and DNA repair enzymes, which have not been associated with

295 g agents is limited because of the action of DNA repair enzymes, which mitigate the damage induced by

296 Thus, Mug joins a very small coterie of DNA repair enzymes whose principal function is to avoid

297 tructurally homologous to exonuclease III, a DNA-repair enzyme with multiple activities.

298 in an increased nuclear localization of the DNA repair enzyme XPA.

299 he relationship between polymorphisms in the DNA repair enzyme, XRCC1 (codons 194, 280, and 399), and

300 Changes in gene expression for cytokines, DNA repair enzymes, zinc transporters, signaling molecul