ライフサイエンスコーパス: DNA synthesis

1 ulation phase, presumably due to protein and DNA synthesis.

2 tolerance through their role in translesion DNA synthesis.

3 e of yeast Poldelta holoenzyme in the act of DNA synthesis.

4 red for histone H3.3 deposition and telomere DNA synthesis.

5 R) catalyzes the first committed reaction in DNA synthesis.

6 with homopolymer instability or translesion DNA synthesis.

7 s their proteolysis, followed by translesion DNA synthesis.

8 E2 and is necessary for initiation of viral DNA synthesis.

9 at specific loci use pathways uncoupled from DNA synthesis.

10 imer-template pairing used for second-strand DNA synthesis.

11 R2 functions in DNA repair and mitochondrial DNA synthesis.

12 eactive oxygen species (ROS) and accelerates DNA synthesis.

13 the advance of the polymerase, slowing down DNA synthesis.

14 and degradation in response to the arrest of DNA synthesis.

15 (HR) and RAD52-POLD3-dependent break induced DNA synthesis.

16 hates (dNDPs) to provide dNTP precursors for DNA synthesis.

17 es (RNRs) are essential enzymes required for DNA synthesis.

18 le for histone (H3-H4)2 deposition following DNA synthesis.

19 DNA ends, problematic lesions that preclude DNA synthesis.

20 dRP lyase gap trimming and template-directed DNA synthesis.

21 the primer terminus on genomic stability and DNA synthesis.

22 ing generation of R-lesions by R-loop-primed DNA synthesis.

23 transiently exposed template strands during DNA synthesis.

24 illomavirus E2 protein onto chromatin during DNA synthesis.

25 nd orchestrates chromatin assembly following DNA synthesis.

26 s observed in G2 after completion of nuclear DNA synthesis.

27 into any DNA oligonucleotide during initial DNA synthesis.

28 S-phase checkpoint monitors the integrity of DNA synthesis.

29 apable of coordinated leading/lagging strand DNA synthesis.

30 ases (RRs) generate deoxyribonucleotides for DNA synthesis.

31 ic acid delivery to Pol alpha and subsequent DNA synthesis.

32 ce of wild-type BRCA1 blocked RNF168-induced DNA synthesis.

33 f Pax7(+) cells likely explains the elevated DNA synthesis.

34 ly factor 1 (CAF-1) deposits histones during DNA synthesis.

35 tide incorporation or completely inhibit the DNA synthesis.

36 PCNA does much more than promote processive DNA synthesis.

37 DNA, effectively increasing processivity of DNA synthesis.

38 ase on Threonine 530 (T530-pSIRT1) modulates DNA synthesis.

39 rs that block reverse transcriptase-mediated DNA synthesis.

40 s chemistry to coordinate the first steps of DNA synthesis.

41 h MUS81 and promotes MUS81-dependent mitotic DNA synthesis.

42 yofibrillar and cytosolic protein as well as DNA synthesis.

43 th important implications for lagging strand DNA synthesis.

44 eocapsids (NCs) and the early stage of viral DNA synthesis.

45 n ssDNA generated gradually during 'in situ' DNA synthesis.

46 s of telomeres synthesized by leading strand DNA synthesis.

47 stent with a role for MCM8IP in HR-dependent DNA synthesis.

48 igens and had no appreciable effect on viral DNA synthesis.

49 ial for genome maintenance through templated DNA synthesis.

50 MG activity to DNA polymerases for efficient DNA synthesis.

51 le secondary mechanism targeting protein and DNA synthesis.

52 ry effect of poly-SUMOylation on HR-mediated DNA synthesis.

53 event during the reinitiation of replicative DNA synthesis.

54 sis of a template protein sequence or direct DNA synthesis.

55 e proteasome, promoting timely resumption of DNA synthesis.

56 PCNA and the nascent DNA, where it regulates DNA synthesis.

57 , including RNA editing and retron satellite DNA synthesis.

58 these steps precede the completion of viral DNA synthesis.

59 e structures by DDX11 to maintain processive DNA synthesis.

60 ns to identify the location and direction of DNA synthesis.

61 cerevisiae Polzeta holoenzyme in the act of DNA synthesis (3.1 angstrom) and without DNA (4.1 angstr

62 The Pif1-dependent stimulation of DNA synthesis across strong protein barriers may be bene

63 ring-shaped structure to promote processive DNA synthesis, acting as a sliding clamp for polymerases

64 are strong blocks to the strand displacement DNA synthesis activity of DNA polymerase delta.

65 ogical perturbations by measuring changes in DNA synthesis after limb denervation.

66 stalled forks facilitates the resumption of DNA synthesis after stress removal.

67 l membrane integrity and by interfering with DNA synthesis against Gram-positive pathogens and in the

68 entral polypurine tract primes second-strand DNA synthesis and a conformational stabilising function

69 ry and co-transcriptional R-loops can impede DNA synthesis and are a major source of genomic instabil

70 ase 1 (CHK1) kinases to transiently suppress DNA synthesis and cell cycle progression.

71 neck (SCCHN) cells and resulted in enhanced DNA synthesis and cell cycle progression.

72 t PCNA degradation and associated effects on DNA synthesis and cell cycle progression.

73 uggests a dual-mechanism of action affecting DNA synthesis and cell membrane integrity.

74 to date has been enhanced by improvements in DNA synthesis and computational design.

75 knockdown of Mcm10 and HP1a induced ectopic DNA synthesis and DNA damage without much of ectopic apo

76 The protocol relies on commercial DNA synthesis and DNA sequencing via Illumina dye sequen

77 s innate immune sensing through encapsidated DNA synthesis and encodes accessory genes that antagoniz

78 quently disengages from the replisome during DNA synthesis and exchanges with free copies from soluti

79 n-of-function mutants, we show that both the DNA synthesis and exonuclease activities of the POLD1 su

80 a novel role for LMO2 in directly promoting DNA synthesis and G1-S progression.

81 hibited prolonged S-phase, were defective in DNA synthesis and had increased DNA damage levels, sugge

82 fective capsid-dependent inhibition of HIV-1 DNA synthesis and infection.

83 ted during base excision repair, gap-filling DNA synthesis and lyase-dependent 5'-end deoxyribose pho

84 ductase (MTHFR) gene, an enzyme essential in DNA synthesis and methylation, have been associated with

85 tive cleavage divisions, persisted even when DNA synthesis and mitosis were blocked by inhibitors.

86 ient B cell progenitors displayed defects in DNA synthesis and passage through the G1/S transition, c

87 mophila avoids host S phase by blocking host DNA synthesis and preventing cell cycle progression into

88 ty as a possible mechanism for XNA-dependent DNA synthesis and provides insights into the constructio

89 Advances in DNA synthesis and recombineering have enabled high-throu

90 beta maintains genome fidelity by catalyzing DNA synthesis and removal of a reactive DNA repair inter

91 corresponding deoxyribonucleotides, used in DNA synthesis and repair.

92 ntial for cellular methylation reactions and DNA synthesis and repair.

93 D52 deficiency reduced spontaneous telomeric DNA synthesis and replication stress-associated recombin

94 As the cost of DNA synthesis and sequencing continues to drop, we antic

95 Improvements in DNA synthesis and sequencing have underpinned comprehens

96 With the rapid advances in DNA synthesis and sequencing technologies and the contin

97 medium is rapidly growing due to advances in DNA synthesis and sequencing.

98 is the high rate of errors that arise during DNA synthesis and sequencing.

99 abasic sites ahead of nascent lagging strand DNA synthesis and subsequent bypass by error-free templa

100 a suicide enzyme, HMCES prevents translesion DNA synthesis and the action of endonucleases that would

101 The G1/S genes encode factors required for DNA synthesis and the G2/M genes contribute to mitosis.

102 isms for nucleotidyl transfer during RNA and DNA synthesis and the origin of primordial nucleic acid

103 uently to facilitate the late stage of viral DNA synthesis and to stabilize NCs containing mature vir

104 generation, oxidative stress, disruption of DNA synthesis, and activation of DNA-repair but also dis

105 the bacterial host, including transcription, DNA synthesis, and cell division.

106 tion of protein synthesis, interference with DNA synthesis, and energy metabolism inhibition.

107 ication in hypoxic conditions, mitochondrial DNA synthesis, and in DNA repair outside the S-phase.

108 de triphosphates (dNTPs) building blocks for DNA synthesis, and is a well-recognized target for cance

109 mportant for efficient HCMV gene expression, DNA synthesis, and the production of infectious HCMV pro

110 ase implicated in DNA repair, lagging-strand DNA synthesis, and the recovery of stalled DNA replicati

111 dNTPs) to a lower level that restricts viral DNA synthesis, and thus prevents replication of diverse

112 y at the G1-S transition, decreased rates of DNA synthesis, and unresolved DNA damage.

113 noblot analyses and transfection, infection, DNA synthesis, apoptosis, migration, cell count, and pro

114 resent an economical and streamlined de novo DNA synthesis approach for engineering a synthetic pathw

115 Genomic stability and accurate DNA synthesis are fundamental for cell development and c

116 thesis of the myofibrillar fraction, but not DNA synthesis, are elevated in muscle of the contralater

117 lus the proteins required for lagging-strand DNA synthesis, are essential for the reaction, as are a

118 for the coordinate inhibition of translesion DNA synthesis as a strategy to improve chemotherapeutic

119 We perform a comprehensive analysis of DNA synthesis at all STR permutations and interrogate th

120 ilon) carries out the bulk of leading strand DNA synthesis at an undisturbed replication fork.

121 Telomerase catalyzes telomeric DNA synthesis at chromosome ends to allow for continued

122 es and point mutations caused by error-prone DNA synthesis at DNA structures.

123 w microhomologies can be created via limited DNA synthesis at secondary-structure forming sequences.

124 pendent cohesin removal is needed to restart DNA synthesis at stalled forks and promote survival foll

125 replication stress, as evidenced by mitotic DNA synthesis at telomeres, and significantly increases

126 hich manifests as increased telomere mitotic DNA synthesis at telomeres.

127 infection occurred after completion of viral DNA synthesis, at the step of 2LTR circle and provirus f

128 To complete DNA synthesis before the onset of mitosis, eukaryotic ce

129 hich plays a specific role in protein-primed DNA synthesis beyond simply harboring the site of primin

130 In contrast to conventional S phase DNA synthesis, BIR proceeds by a migrating D-loop and re

131 X protein does not affect viral latent/lytic DNA synthesis but is required for cleavage and processin

132 tivity, DNA damage responses, or unscheduled DNA synthesis but to loss of an ATR function at centrome

133 itical for converging replisomes to complete DNA synthesis, but the pathways that mediate fork conver

134 e excises misincorporated nucleotides during DNA synthesis, but these events are rare.

135 eplicate the damaged DNA, allowing stringent DNA synthesis by a replicative polymerase to resume beyo

136 d strand exchange is immediately followed by DNA synthesis by a slow polymerase.

137 ite mutation further enhances the rate of NP-DNA synthesis by an additional 21-fold.

138 thermore, Pif1 increases strand-displacement DNA synthesis by DNA polymerase delta and allows DNA rep

139 Lagging strand DNA synthesis by DNA polymerase requires RNA primers pro

140 omotes the regular priming of lagging-strand DNA synthesis by facilitating DNA polymerase alpha funct

141 ocation to NPCs but impede the resumption of DNA synthesis by homologous recombination (HR).

142 the dimers by secondary UV irradiation, and DNA synthesis by Pol delta.

143 n the modulation of the rate and fidelity of DNA synthesis by pol delta.

144 ovide insight into the physiological role of DNA synthesis by pol eta and have implications for our u

145 shots of catalytic events during gap-filling DNA synthesis by pol mu.

146 s result in greater involvement of mutagenic DNA synthesis by Pol zeta as well as diminished proofrea

147 However, error-prone DNA synthesis by PrimPol using the G4 template sequence

148 nd on ring-shaped hexameric helicases to aid DNA synthesis by processively unzipping the parental DNA

149 nder Rnr1 depletion, limited dNTP pools slow DNA synthesis by replicative Pols and provoke the incorp

150 It has been assumed that DNA synthesis by the leading- and lagging-strand polymer

151 of AraC derives from its ability to inhibit DNA synthesis by the replicative polymerases (Pols); the

152 detectable polymerase activity and inhibited DNA synthesis by the replisomes of E. coli and T7 in the

153 anemia, which results from the inhibition of DNA synthesis by trapping folate cofactors in the form o

154 nstitution experiments and demonstrated that DNA synthesis by two known mitochondrial DNA polymerases

155 Our findings demonstrate that "correct" DNA synthesis can result in errors when template dynamic

156 Nuclear DNA synthesis ceased almost immediately following VACV i

157 s according to algorithmic rules quantifying DNA synthesis complexity, sgRNA expression, sgRNA target

158 A), a nuclear scaffolding protein pivotal in DNA synthesis, controls neutrophil survival through its

159 ition in vitro, it is required for efficient DNA synthesis-coupled nucleosome assembly.

160 The kidneys were evaluated for DNA synthesis, cytokine/chemokine synthesis, cytoskeleta

161 he RNA:DNA endonuclease RNAse H1 rescues the DNA synthesis defects and suppresses DNA damage caused b

162 DNA synthesis revealed that the fidelity of DNA synthesis depends on local sequence context.

163 s activity enables TGIRT enzymes to initiate DNA synthesis directly at the 3' end of a DNA strand whi

164 s function in multiple pathways that involve DNA synthesis: DNA replication across G-quadruplexes; br

165 observe two alternate configurations of the DNA synthesis domain in the CMG-bound Pol epsilon.

166 Alternatively, replisomes can reprime DNA synthesis downstream of the lesion, creating a singl

167 replicative helicase, but did not reinitiate DNA synthesis due to continued lack of dNTPs.

168 CM8IP as a key regulator of MCM8-9-dependent DNA synthesis during DNA recombination and replication.

169 ion cycle protein 45 (Cdc45) is required for DNA synthesis during genome duplication, as a component

170 ctivity is required to activate compensatory DNA synthesis during mitosis and to resolve mitotic inte

171 of DNA replication origin firing and ongoing DNA synthesis during S-phase itself, respectively, and h

172 mutations, lacks a LMW-dT pool, the initial DNA synthesis during T-starvation and the resistance pha

173 ystems (sia operon), and a metal-independent DNA synthesis enzyme (nrdFEI.2).

174 efficient fork convergence and completion of DNA synthesis, even in the absence of type II topoisomer

175 tion of RNA RTs with very high complementary DNA synthesis fidelities, even in the absence of proofre

176 nucleotide was in the first coding position, DNA synthesis fidelity was similar to that observed with

177 al an unexpected role for RAD52 in promoting DNA synthesis following replication stress.

178 Data are most consistent with the extent of DNA synthesis from the invading end being the primary de

179 development besides its bonafide translesion DNA synthesis function, and suggest that targeting RAD6B

180 Rapid advances in DNA synthesis, genetic manipulation, and biosensors have

181 Once DNA synthesis has ceased, PCNA must be unloaded.

182 ine, and society, and recent improvements in DNA synthesis have enabled the manipulation of megabase

183 eraction is required for initiation of viral DNA synthesis.IMPORTANCE Human papillomaviruses (HPVs) a

184 D18-SLF1 axis was responsible for initiating DNA synthesis in a manner that also required the break-i

185 o deoxyribonucleotides and are essential for DNA synthesis in all organisms.

186 ntileukemic effects, primarily by inhibiting DNA synthesis in proliferating cells.

187 The asymmetric DNA synthesis in rad53-1 cells is suppressed by elevated

188 The product metal is not observed during DNA synthesis in the presence of magnesium.

189 d the accompanying inhibition of chromosomal DNA synthesis in UVB-irradiated keratinocytes.

190 w that ectopic dATM is sufficient to promote DNA synthesis in wild-type fat body cells.

191 Our findings suggest that DNA synthesis increases the stability of the recombinati

192 ng is blocked, diverging CMGs do not support DNA synthesis, indicating that after bypass CMGs encount

193 ariants and, despite advances in large-scale DNA synthesis, individual synthesis of each desired DNA

194 DNA synthesis inhibition was dependent on the UPR effect

195 und, sir-2.1 over-expression causes an FUDR (DNA synthesis inhibitor)-dependent reduction in pharynge

196 To overcome this, we use DNA synthesis inhibitors (hydroxyurea and 1-beta-d-arabi

197 The de novo DNA synthesis involves elongation of the G-rich strand o

198 DNA synthesis is a fundamental requirement for cell prol

199 nd that the exchange rate depends on whether DNA synthesis is active or arrested.

200 Translesion DNA synthesis is an essential process that helps resume

201 f initiation and terminate replication after DNA synthesis is complete.

202 on holoenzyme, critical to understanding how DNA synthesis is coordinated with unwinding and the DNA

203 ion is essential for cell proliferation, and DNA synthesis is generally initiated by dedicated replic

204 In contrast, strong inhibition of DNA synthesis is observed.

205 ve found that efficiency of polymerase gamma DNA synthesis is reduced after this quadruplex is expose

206 ombination of modern biotechnologies such as DNA synthesis, lambda red recombineering, CRISPR-based e

207 merase, Pol epsilon, move beyond the site of DNA synthesis, likely unwinding template DNA.

208 ve chromatin on the leading strand following DNA synthesis may depend upon these lysine methyltransfe

209 abolism for many cellular pathways including DNA synthesis, metabolism and maintenance.

210 Here, we report a multiplexed enzymatic DNA synthesis method using maskless photolithography.

211 e error correction methods, and to benchmark DNA synthesis methods.

212 sociated replication defects trigger mitotic DNA synthesis (MiDAS) at telomeres in a RAD52-dependent,

213 Moreover, these events lead to mitotic DNA synthesis (MiDAS) at telomeres mediated by RAD52 thr

214 telomeres, catalyzes RAD52-dependent mitotic DNA synthesis (MiDAS) specifically at telomeres to drive

215 lize RPA-generated R-loops for initiation of DNA synthesis, mimicking the process of replication rest

216 NR increased DNA synthesis, mitotic index, and mass restoration in th

217 independent of either viral RNA packaging or DNA synthesis, multiple substitutions in the CTD to mimi

218 ded DNA (dsDNA) to use as a template for the DNA synthesis needed to fill the gap created by RecBCD.

219 eration and cell cycle regulation, including DNA synthesis (NPAT), DNA damage response (ATM), mitosis

220 A time-course of DNA synthesis (nuclear and kinetoplast DNA), duplication

221 R10015 specifically blocks viral DNA synthesis, nuclear migration, and virion release.

222 zation of obtained diene products and the on-DNA synthesis of DNA-tagged difluorinated isocoumarin ha

223 th autoimmune disease linked to uncontrolled DNA synthesis of endogenous retroelements.

224 Although average rates of DNA synthesis on leading and lagging strands are similar

225 hat capture the post-translocated product of DNA synthesis on templates composed entirely of 2'-deoxy

226 Given the impact of error-free DNA synthesis on the genomic integrity and differentiati

227 The five T4 proteins that catalyze DNA synthesis on the leading strand, plus the proteins r

228 sed to allow efficient DNA replication, with DNA synthesis on the nontranslocating strand rectifying

229 lly, the investigated metallohelices inhibit DNA synthesis on the RNA template containing four repeat

230 uding through a failure to properly suppress DNA synthesis on UVB-damaged DNA templates.

231 CE Using computer algorithms and large-scale DNA synthesis, one or more ORFs of a microbial pathogen

232 n binding was coupled to strand-displacement DNA synthesis, only one of the two binding modes was obs

233 ing a protein-template-directed mechanism of DNA synthesis opposite undamaged and damaged guanine.

234 emarkably, thapsigargin did not inhibit bulk DNA synthesis or activate Chk1 in cells depleted of Clas

235 , neither treatment significantly influenced DNA synthesis or mitosis in cardiac tissue after amputat

236 , D1/D3 in macrophages, without evidence for DNA synthesis or mitosis.

237 lysis of genes encoding proteins involved in DNA synthesis or RNA transcription did not reveal any mu

238 erred resistance; most of these drugs target DNA synthesis or topoisomerase and cause DNA damage.

239 POL rescues fork degradation by reinitiating DNA synthesis past DNA lesions.

240 an engineered polymerase and is required for DNA synthesis past the adduct.

241 rs present the structures of the translesion DNA synthesis polymerase Rev1 in complex with three of t

242 Shear forces promote DNA synthesis, polyploidization, and maturation in MKs,

243 -conjugating enzyme critical for translesion DNA synthesis, potentiates beta-catenin stability/activi

244 Telomeric MiDAS is a conservative DNA synthesis process, potentially mediated by break-ind

245 ative derivative, 3a, significantly inhibits DNA synthesis, produces fragmented nucleoids, and alters

246 Remarkably, DNA synthesis progresses further along the lagging stran

247 Simultaneous measurement of protein and DNA synthesis provides necessary mechanistic insight abo

248 RHA did not enhance the DNA synthesis rate until incorporation of the first few

249 S-phase length is determined by DNA synthesis rate, which depends on the number of activ

250 d Esa1 each contribute separately to maximum DNA synthesis rates.

251 Asp256 that serves an important role during DNA synthesis reactions.

252 oordinate both high fidelity and translesion DNA synthesis requires a means to regulate recruitment a

253 Our experimental results show that the DNA synthesis requires formation of a heteroduplex dsDNA

254 hic and kinetic analyses of 2-nt gap-filling DNA synthesis revealed that the fidelity of DNA synthesi

255 A single, systemic dose of methotrexate, a DNA-synthesis (S phase) inhibitor, has been used since 1

256 at reconstituting leading and lagging strand DNA synthesis separately and as an integrated replicatio

257 When DNA replication stress is encountered, DNA synthesis stalls until the stress is ameliorated.

258 k, we present the first one-pot liquid-phase DNA synthesis technique which allows the addition of one

259 DNA synthesis technology has progressed to the point tha

260 of Pol delta reveal a significant slowing of DNA synthesis that can be fully reversed by reduction of

261 st thapsigargin led to a rapid inhibition of DNA synthesis that was attributable to a combination of

262 CTD dephosphorylation is associated with HBV DNA synthesis, the CTD state of phosphorylation may not

263 However, in the context of lagging strand DNA synthesis, the efficient disruption of a nucleosome

264 During active DNA synthesis, the replisome tightly associates with DNA

265 d block HIV-1 reverse transcriptase-mediated DNA synthesis, thereby inhibiting HIV-1 replication.

266 s monitoring of the kinetics and fidelity of DNA synthesis through 20,000 sequences comprising all ST

267 d replication, Pif1-dependent stimulation of DNA synthesis through a nucleosome or Reb1 barrier is pr

268 However, current studies of DNA synthesis through STRs are restricted to a handful o

269 eoxynucleotide triphosphates (dNTPs) to fuel DNA synthesis, thus requiring penetration of dNTPs into

270 Translesion DNA synthesis (TLS) and homologous recombination (HR) co

271 Translesion DNA synthesis (TLS) is the ability of DNA polymerases to

272 Translesion DNA synthesis (TLS) mediated by low-fidelity DNA polymer

273 tion of AraC, the lower-fidelity translesion DNA synthesis (TLS) polymerase Poleta is proficient, ins

274 ted to dsDNA with an appropriate translesion DNA synthesis (TLS) polymerase, followed by PCR amplific

275 dsDNA) form by using appropriate translesion DNA synthesis (TLS) polymerases and then can be amplifie

276 oting replication fork reversal, translesion DNA synthesis (TLS), and repriming.

277 In translesion DNA synthesis (TLS), specialized DNA polymerases replica

278 ed for the extension reaction in translesion DNA synthesis (TLS).

279 -phase and may be carried out by translesion DNA synthesis (TLS).

280 ase delta (Pol delta) is thought to catalyze DNA synthesis to fill in the gaps resulting from mispair

281 ble-strand break (DSB) repair often requires DNA synthesis to fill the gaps generated upon alignment

282 pose that TRF1 facilitates S-phase telomeric DNA synthesis to prevent illegitimate mitotic DNA recomb

283 es incorporated at specific positions during DNA synthesis, to generate highly diverse protein-varian

284 pecialized cytoplasmic factory regions where DNA synthesis, transcription, translation, and virion as

285 mitotic progression was impaired and mitotic DNA synthesis triggered.

286 activity and H3K4me are crucial for faithful DNA synthesis under replication stress, especially in hi

287 ations for other essential functions such as DNA synthesis via RNR which is required for C. jejuni's

288 In each case thapsigargin-resistant DNA synthesis was due to an increase in replication orig

289 and myofibrillar protein synthesis, but not DNA synthesis, was also elevated.

290 Second-strand DNA cleavage and second-strand DNA synthesis were investigated in vitro using purified

291 with the natural A, T, G and C bases during DNA synthesis, which allows for labeling of replicating

292 alling at DNA structures induces error-prone DNA synthesis, which constrains STR expansion.

293 ough an increase in the enzymes required for DNA synthesis, which include nucleotide-biosynthetic enz

294 a decreased ability to subsequently restart DNA synthesis, which is normally dependent upon HR-media

295 sing building block availability for RNA and DNA synthesis, which is required for cell growth and pro

296 2-induced S-phase re-entry, Bex1 facilitated DNA synthesis while inhibiting cell death.

297 uring the lytic phase, the templates limited DNA synthesis, while later the templates were in excess,

298 latin inhibited de novo purine synthesis and DNA synthesis, with amino acid deprivation augmenting ci

299 s (5meCs) caused by passive dilution through DNA synthesis without daughter strand methylation and ac

300 naB and the associated replisome to continue DNA synthesis without impediment, with leading strand re