ライフサイエンスコーパス: Drosophila embryo

1 e range of transcription factors in the live Drosophila embryo.

2 myosin dynamics during dorsal closure in the Drosophila embryo.

3 identify interacting partners of Mst in the Drosophila embryo.

4 expression patterns in the blastoderm-stage Drosophila embryo.

5 rane cytoskeleton restraint in the syncytial Drosophila embryo.

6 200 spatiotemporal expression domains in the Drosophila embryo.

7 ated by its non-catalytic CUB domains in the Drosophila embryo.

8 ing the regulation of hunchback in the early Drosophila embryo.

9 es of epithelial cell junctions in the early Drosophila embryo.

10 uch as the development of the trachea of the Drosophila embryo.

11 rior-posterior patterning genes in the early Drosophila embryo.

12 amics during single-cell wound repair in the Drosophila embryo.

13 (eve) stripe 2 expression in the precellular Drosophila embryo.

14 omplex epithelial folding event in the early Drosophila embryo.

15 controlling brinker (brk) expression in the Drosophila embryo.

16 nder tension at tricellular junctions in the Drosophila embryo.

17 ngement of the tissues on the surface of the Drosophila embryo.

18 nd microtubules in the epidermis of the late Drosophila embryo.

19 tions during germband extension in the early Drosophila embryo.

20 P) and dorsal-ventral (DV) axes of the early Drosophila embryo.

21 of a tubular epithelium resembling the early Drosophila embryo.

22 hibition dynamics within the geometry of the Drosophila embryo.

23 cific activation of the Toll receptor in the Drosophila embryo.

24 m development of vertebrates and that of the Drosophila embryo.

25 using the rapid division cycles in the early Drosophila embryo.

26 thering at Golgi membranes in the developing Drosophila embryo.

27 egulation of other Runt targets in the early Drosophila embryo.

28 apid and synchronous activation in the early Drosophila embryo.

29 the mesoderm and neuroectoderm in the early Drosophila embryo.

30 hat controls the dorsoventral pattern of the Drosophila embryo.

31 how periodic patterns are established in the Drosophila embryo.

32 pathway responsible for segmentation in the Drosophila embryo.

33 lopment and differentiation processes in the Drosophila embryo.

34 anterior-posterior axis along the developing Drosophila embryo.

35 elopmental control genes active in the early Drosophila embryo.

36 is pervasively used in the patterning of the Drosophila embryo.

37 long the anterior posterior (AP) axis of the Drosophila embryo.

38 axon guidance and target recognition in the Drosophila embryo.

39 distribution of zygotic nuclei in the early Drosophila embryo.

40 distribution of zygotic nuclei in the early Drosophila embryo.

41 to dissect Erk-dependent fates in the early Drosophila embryo.

42 n and activation of Torso at the ends of the Drosophila embryo.

43 ection of a proneural cell fate in the early Drosophila embryo.

44 polarity during convergent extension in the Drosophila embryo.

45 essor of Hairless [Su(H)], in patterning the Drosophila embryo.

46 organizes the anterior/posterior axis of the Drosophila embryo.

47 anscription factor Dorsal in the precellular Drosophila embryo.

48 alyzing histone marks and gene expression in Drosophila embryos.

49 hat mediates rapid furrow formation in early Drosophila embryos.

50 ndle elongation using experimental data from Drosophila embryos.

51 riven terminal signaling patterning in early Drosophila embryos.

52 f fast cellular dynamics across gastrulating Drosophila embryos.

53 s-knirps, hunchback, and snail-in developing Drosophila embryos.

54 rtex, maintain genome integrity in syncytial Drosophila embryos.

55 tudy scaled anterior-posterior patterning in Drosophila embryos.

56 using light sheet microscopy to image whole Drosophila embryos.

57 ablishment of the anterior-posterior axis in Drosophila embryos.

58 detect and map genome methylation in stage 5 Drosophila embryos.

59 these insertions, called the CPTI lines, in Drosophila embryos.

60 and influence the resolution of infection in Drosophila embryos.

61 r tissue-specific silencer activity in whole Drosophila embryos.

62 thway is essential for wound closure in late Drosophila embryos.

63 tions in the dorsal and ventral epithelia of Drosophila embryos.

64 behaviors, such as during dorsal closure in Drosophila embryos.

65 d cell motility across the segment border in Drosophila embryos.

66 sults in the formation of thinner muscles in Drosophila embryos.

67 nd repair in the epidermis of early and late Drosophila embryos.

68 ificities that are sequentially expressed in Drosophila embryos.

69 cytoplasmic dynein-driven lipid droplets in Drosophila embryos.

70 for function in human colon cancer cells and Drosophila embryos.

71 intenance elements during DNA replication in Drosophila embryos.

72 modify the lifetime of Dronpa-Bcd in living Drosophila embryos.

73 ession (stripes 3 and 7) in blastoderm stage Drosophila embryos.

74 mechanical response of motor neurons in live Drosophila embryos.

75 cluster spatial gene expression patterns in Drosophila embryos.

76 pared gene expression in haploid and diploid Drosophila embryos.

77 ia its phosphatase domain with N-cadherin in Drosophila embryos.

78 rom RNA in situ hybridization experiments of Drosophila embryos.

79 sets up the anterior-posterior axis in early Drosophila embryos.

80 culturing of primary cells dissociated from Drosophila embryos.

81 es of the Hunchback (Hb) protein gradient in Drosophila embryos.

82 ity and emergence of coordinated movement in Drosophila embryos.

83 sing optogenetic stimulation of myosin-II in Drosophila embryos.

84 pathway were enriched in nascent myotubes in Drosophila embryos.

85 ters within the same polar granules in early Drosophila embryos.

86 rehensive investigation of these proteins in Drosophila embryos.

87 with restriction of Svb expression in early Drosophila embryos.

88 genetic events that drive cellularization in Drosophila embryos.

89 present high resolution Hi-C data from early Drosophila embryos.

90 both correct and off-target muscle fibers in Drosophila embryos.

91 of heterochromatin domain formation in early Drosophila embryos.

92 r of primordial germ cell (PGC) formation in Drosophila embryos.

93 muli: anoxia-induced developmental arrest in Drosophila embryos.

94 contraction and tissue folding in developing Drosophila embryos.

95 opy (RLSM) to image highly opaque late-stage Drosophila embryos.

96 he three-dimensional epidermal structures of Drosophila embryos.

97 Dorsal in dorsal-ventral axis patterning of Drosophila embryos.

98 e examine transcriptional bursting in living Drosophila embryos.

99 ve mesoderm and neurogenic ectoderm of early Drosophila embryos.

100 int segmentation and cell tracking in entire Drosophila embryos.

101 a new regulator of beta-catenin abundance in Drosophila embryos.

102 y the segmentation gene cascade in the early Drosophila embryo [1].

103 of conformational changes in Zelda-depleted Drosophila embryos; (3) patient-specific aberrant chroma

104 mporal control of transcription in the early Drosophila embryo, a model system for transcriptional re

105 ling of morphogen gradients in the syncytial Drosophila embryo, a single cell with multiple dividing

106 In Drosophila embryos, a concentration gradient of nuclear

107 In Drosophila embryos, a nuclear gradient of the Dorsal (Dl

108 ng cellularization, the first cytokinesis in Drosophila embryos, a reservoir of microvilli unfolds to

109 required for cell-autonomous Hh response in Drosophila embryos, alone suffices to rescue embryonic H

110 ndent inductive signaling event in the early Drosophila embryo, an experimental system that offers un

111 the onset of ventral furrow formation in the Drosophila embryo and in the process of hair-cell determ

112 precursors cover the ventral surface of the Drosophila embryo and larva and provide templates for cu

113 s a chemoattractant for PGC migration in the Drosophila embryo and that downstream signaling proteins

114 on the Bicoid/Hunchback system in the early Drosophila embryo and that this system achieves approxim

115 the specification of the mesectoderm in the Drosophila embryo and the endomesoderm in the sea urchin

116 Septin complex was purified from Drosophila embryos and also reconstituted from recombina

117 n epidermal cells surrounding wounds in late Drosophila embryos and early larvae.

118 DNA modification is highly dynamic in early Drosophila embryos and forms an epigenetic mark.

119 l analysis on endogenous Notch purified from Drosophila embryos and found that the glycosylation stat

120 ctopic expression of the spider Antp gene in Drosophila embryos and imaginal tissue that this unique

121 thermore, LC8 decorates microtubules both in Drosophila embryos and in HeLa cells, increases the micr

122 to study a Hox gene cluster in cryosectioned Drosophila embryos and labelled around 30 RNA species in

123 In Drosophila embryos and larvae, a small number of identif

124 olymerase (Pol II) is a pervasive feature of Drosophila embryos and mammalian stem cells, but its rol

125 ion tissue anisotropy maps across developing Drosophila embryos and quantified differences in cell-sh

126 ormed ChIP-seq experiments on tightly staged Drosophila embryos and show that massive recruitment of

127 er-like transcription factor Zelda in living Drosophila embryos and showed that no thermodynamic or n

128 ease recognition site into I-SceI expressing Drosophila embryos and used Illumina amplicon sequencing

129 entified as the earliest wound attractant in Drosophila embryos and zebrafish larvae.

130 gulating spatial gene expression patterns in Drosophila embryo, and show that DNA shape-based models

131 atterns the dorsal-ventral axis of the early Drosophila embryo, and we found that an empirical descri

132 ila eggs, duplication of free centrosomes in Drosophila embryos, and centrosome amplification in cult

133 re we show that R-loops form at many PREs in Drosophila embryos, and correlate with repressive states

134 A loss of LC8 function causes apoptosis in Drosophila embryos, and its overexpression induces malig

135 idate MEDUSA by quantifying wound closure in Drosophila embryos, and we show that the results of our

136 Terminal regions of the Drosophila embryo are patterned by the localized activat

137 tion and cytoskeletal planar polarity in the Drosophila embryo are regulated by a common signal provi

138 Fixed Drosophila embryos are hybridized in solution with a mix

139 segments in Drosophila melanogaster Whereas Drosophila embryos are long-germ, with segments specifie

140 rmation, in bits, using the gap genes in the Drosophila embryo as an example.

141 ls migrate from posterior to anterior of the Drosophila embryo as two bilateral streams of cells to s

142 te synchronously towards the anterior of the Drosophila embryo as two distinct groups located on each

143 Using stripe 2 of the even-skipped gene in Drosophila embryos as a case study, we dissect the regul

144 Here, we introduce Drosophila embryos as a platform to study the energy bud

145 inant of epithelial apical-basal polarity in Drosophila embryos, as an upstream component of the Hipp

146 The Drosophila embryo at the mid-blastula transition (MBT) c

147 rentially with one of the two centrosomes in Drosophila embryos at cellular blastoderm stage.

148 Segmentation of the Drosophila embryo begins with the establishment of spati

149 ted to reconstitute Galileo transposition in Drosophila embryos but no events were detected.

150 tions as a Dpp (Decapentaplegic) receptor in Drosophila embryos, but that its activity is normally in

151 ional during the rapid mitotic cycles of the Drosophila embryo; but its genetic inactivation had no c

152 e how the BMP gradient is interpreted in the Drosophila embryo by combining live imaging with computa

153 nes contribute to the regionalization of the Drosophila embryo by establishing fields in which specif

154 ogy of epithelial cells in the cellularizing Drosophila embryo by injecting magnetic particles and st

155 Knirps has essential roles in patterning the Drosophila embryo by means of short-range repression, an

156 boundaries of gene expression emerge in the Drosophila embryo by measuring the absolute number of ac

157 pathway specifies neuronal identities in the Drosophila embryo by regulating developmental patterning

158 believed to be established in pre-blastoderm Drosophila embryos by the diffusion of Bcd protein after

159 genous cargoes, lipid droplets purified from Drosophila embryos, can be used to perform high-precisio

160 In Drosophila embryos, caudal visceral mesoderm (CVM) cells

161 Loss and gain of pbl function in Drosophila embryos cause pattern defects that indicate a

162 Our findings show that in Drosophila embryos, Cdk1 positive feedback serves primar

163 om several systems including mouse liver and Drosophila embryos characterizing over 5,500 and 13,000

164 For Drosophila embryo cleavage, this growth is rapid but reg

165 H2a and H2b are stored in lipid droplets in Drosophila embryos complexed with the protein Jabba.

166 event accumulation of excess histones, early Drosophila embryos contain massive extranuclear histone

167 ning of the dorsal-ventral axis in the early Drosophila embryo depends on the nuclear distribution of

168 The dorsoventral (DV) patterning of the Drosophila embryo depends on the nuclear localization gr

169 ch to our understanding of these events: the Drosophila embryo; developing and regenerating mouse mus

170 hat exhibit highly dynamic behavior in early Drosophila embryo development.

171 quired for cells to form following syncytial Drosophila embryo development.

172 ion in embryo size affects patterning of the Drosophila embryo dorsal-ventral (DV) axis is not known.

173 Drosophila embryo dorsoventral (DV) polarity is defined

174 itch-like entry into mitosis observed in the Drosophila embryo during the 14(th) mitotic cycle is tim

175 y network function, we performed ATAC-seq on Drosophila embryos during the establishment of the segme

176 phosphatase (GTPase) remains inactive within Drosophila embryos during the first two-thirds of embryo

177 contractile cells on the ventral side of the Drosophila embryo ensures robust tissue folding.

178 Here, we show that laser wounding of the Drosophila embryo epidermis triggers an instantaneous ca

179 Using whole-mount in situ hybridization in Drosophila embryos exposed to constitutively active RTK

180 Here we demonstrate that Drosophila embryos expressing catalytically deficient Tr

181 From cross-linked Drosophila embryo extracts, we detected 29931 cross-link

182 In early Drosophila embryos, forks starting from closely spaced o

183 In the Drosophila embryo, formation of a bone morphogenetic pro

184 which cell-surface proteins are expressed in Drosophila embryos from GAL4-dependent insertion lines a

185 In the Drosophila embryo, germ plasm is anchored to the posteri

186 The Drosophila embryo has recently emerged as a powerful mod

187 We find that elevating Dishevelled levels in Drosophila embryos has paradoxical effects, promoting th

188 uter simulations and quantitative imaging of Drosophila embryos have been used to recreate the dynami

189 ing human embryonic stem cells and the early Drosophila embryo, have begun to challenge this view.

190 n of microtubule alignment within developing Drosophila embryos, here we demonstrate that microtubule

191 ith those of the corresponding system in the Drosophila embryo, highlighting distinct and common path

192 Here, we find that in early Drosophila embryos, histone balance in the nuclei is reg

193 r (SOP) cells within distinct regions of the Drosophila embryo in an epidermal growth factor-dependen

194 probes are hybridized to fixed, mixed-staged Drosophila embryos in 96-well plates.

195 tocol for RNA in situ hybridization (ISH) to Drosophila embryos in a 96-well format.

196 a microfluidic device to rapidly orient >700 Drosophila embryos in parallel for end-on imaging.

197 approach to annotate developmental stage for Drosophila embryos in the gene expression images.

198 nce of a second mechanism that polarizes the Drosophila embryo, in addition to the ventrally restrict

199 We examined dNTP metabolism in the early Drosophila embryo, in which gastrulation is preceded by

200 lled RNA Polymerase II (Pol II) in the early Drosophila embryo, including four of the eight Hox genes

201 oundaries that separate every segment of the Drosophila embryo into anterior and posterior compartmen

202 De novo formation of cells in the Drosophila embryo is achieved when each nucleus is surro

203 The development of the precellular Drosophila embryo is characterized by exceptionally rapi

204 Dorsoventral (DV) patterning of the Drosophila embryo is controlled by a concentration gradi

205 Gene expression in the Drosophila embryo is controlled by functional interactio

206 The dorsal-ventral axis of the Drosophila embryo is determined by the graded distributi

207 pical secretion from epithelial tubes of the Drosophila embryo is mediated by apical F-actin cables g

208 Gastrulation of the Drosophila embryo is one of the most intensively studied

209 The early Drosophila embryo is patterned by graded distributions o

210 The anterior region of the Drosophila embryo is patterned by the concentration grad

211 Dorsoventral patterning of the Drosophila embryo is regulated by graded distribution of

212 the pattern of Toll activation in the early Drosophila embryo is robust to gene dosage of its locall

213 Cellularization of the Drosophila embryo is the process by which a syncytium of

214 Furrow formation in early syncytial Drosophila embryos is exceptionally rapid, with furrows

215 dies of dorsal-ventral polarity in the early Drosophila embryo, is well known for its role in the inn

216 es also function in vivo: when injected into Drosophila embryos lacking droplet-bound histones, bacte

217 A-seq to evaluate differential expression in Drosophila embryos lacking endosymbionts (control) to th

218 In Drosophila embryos lacking the alpha(2)delta-3 subunit o

219 We propose that in Drosophila embryos, lipid droplets serve as a histone bu

220 cules via RNA strand exchange in a cell-free Drosophila embryo lysate, a step beyond simple buffered

221 In the early Drosophila embryo, measurements of the morphogen Dorsal,

222 In Drosophila embryos, mechanical tension stabilizes myosin

223 ell wound repair in the genetically amenable Drosophila embryo model.

224 In Drosophila, embryos mutant for giant show a gap in the a

225 In many cell types, including early Drosophila embryos, Nuf/FIP3, a Rab11 effector, mediates

226 er cells, and most restore Wnt regulation in Drosophila embryos null for both fly APCs.

227 fects of the geometry of the early syncytial Drosophila embryo on the effective diffusivity of cytopl

228 hereas the preparation of primary cells from Drosophila embryos only requires 2-4 h.

229 imaging of developmental gene expression in Drosophila embryos opens up exciting new prospects for u

230 nuclear concentration gradient in the early Drosophila embryo, patterning the dorsal-ventral (DV) ax

231 In Drosophila embryo, Pol II pausing is known to regulate t

232 d this question in two contexts of the early Drosophila embryo: premature cell division during mesode

233 LC8 decorates microtubules in vitro and in Drosophila embryos, promotes microtubule assembly, and s

234 prior to nuclear envelope breakdown (NEB) in Drosophila embryos, proper centrosome separation does no

235 Drosophila embryos provide a superb model.

236 Drosophila embryos provide an outstanding model for defi

237 Patterning of the terminal regions of the Drosophila embryo relies on the gradient of phosphorylat

238 The maternal-to-zygotic transition in the Drosophila embryo requires accurate control of the level

239 Patterning in the Drosophila embryo requires local activation and dynamics

240 ow that synchronization of the cell cycle in Drosophila embryos requires accurate nuclear positioning

241 TRIP and NOPO E3 ligases in human cells and Drosophila embryos, respectively, and show that TRIP pro

242 tent with this, removal of the ASAD from the Drosophila embryo results in beta-cat/Arm accumulation a

243 functions of both Forkhead genes in the same Drosophila embryo results in defective hearts with missi

244 ing DNA and an increase in S-phase length in Drosophila embryos, revealing an unexpected role for Cdk

245 nd the activation of the morphogen dorsal in Drosophila embryos show striking structural and function

246 -5, KLP61F, in astral, centrosome-controlled Drosophila embryo spindles and to test the hypothesis th

247 In early Drosophila embryos, ST also caused increased microtubule

248 In this issue, Song et al. (2017) show that Drosophila embryos synthesize a large fraction of nucleo

249 singly, despite the breakneck speed at which Drosophila embryos synthesize DNA, maternally deposited

250 esolution dataset of a genetically perturbed Drosophila embryo that captures all cells in 3D.

251 . show through analysis of the oskar mRNA in Drosophila embryos that regulatory elements within mRNAs

252 In a previous study, we discovered that in Drosophila embryos, the adhesion molecule Sidekick (Sdk)

253 We propose that in Drosophila embryos, the latter process (anaphase B) depe

254 In Drosophila embryos, the midblastula transition (MBT) dra

255 In early Drosophila embryos, the transcription factor Dorsal regu

256 In the Drosophila embryo, these cells have been termed founder

257 In the Drosophila embryo, this process occurs asymmetrically be

258 tes a highly ordered square cell grid in the Drosophila embryo through sequential and spatially regul

259 larization in the anterior pole of the early Drosophila embryo to explore how cells compete for space

260 Here we use the Drosophila embryo to investigate how hemocytes (Drosophi

261 Here we use the Drosophila embryo to model human disease mutations that

262 BMPs changed the steep BMP gradient found in Drosophila embryos to a shallower profile, analogous to

263 article tracking velocimetry in gastrulating Drosophila embryos to measure the movement of cytoplasm

264 enous, GFP-tagged Augmin and gamma-TuRC from Drosophila embryos to near homogeneity using a novel one

265 ion, the first complete cytokinetic event in Drosophila embryos, to show that cleavage furrow ingress

266 In the Drosophila embryo, Toll is required to establish gene ex

267 The Drosophila embryo transiently exhibits a double-segment

268 The Drosophila embryo undergoes several cycles of rapid furr

269 irst wave of de novo transcription in living Drosophila embryos using dual-fluorescence detection of

270 id from three dipteran species in transgenic Drosophila embryos using the Drosophila bicoid cis-regul

271 ws for the quantification of single mRNAs in Drosophila embryos, using commercially available smFISH

272 Cell rearrangements shape the Drosophila embryo via spatially regulated changes in cel

273 ts within single cells of fixed, whole-mount Drosophila embryos via a combination of FISH, immunohist

274 by studies of pattern formation in the early Drosophila embryo, we analyze cascades of 2-state reacti

275 genetic and imaging experiments in the early Drosophila embryo, we describe a signal integration mech

276 ng dorsal-ventral (DV) axis formation in the Drosophila embryo, we find that the poised enhancer sign

277 specific transcription factors active in the Drosophila embryo, we found that binding of all factors

278 on genetic and imaging studies in the early Drosophila embryo, we found that Torso RTK signaling can

279 he anterior-posterior (AP) patterning of the Drosophila embryo, we identified embryonic geometry as a

280 To address this issue in the early Drosophila embryo, we sought to count individual materna

281 Using single-molecule mRNA quantification in Drosophila embryos, we determine the magnitude of fluctu

282 tivation approaches and live-cell imaging in Drosophila embryos, we dissect the role of condensin I i

283 Using Drosophila embryos, we have exploited the ease of manipu

284 programs that ultimately lead to patterns in Drosophila embryos, we manipulate maternally supplied pa

285 By monitoring transcription in living Drosophila embryos, we provide the first evidence for tr

286 alize nascent transcripts in single cells in Drosophila embryos, we reveal how two target enhancers r

287 uppel shadow enhancer configurations in live Drosophila embryos, we showed that individual member enh

288 maging, and time-resolved ChIP-seq assays in Drosophila embryos were used to dissect the ERK-dependen

289 Here we address this question using early Drosophila embryos where the maternal gradient Bicoid (B

290 ty in these mutants is evident in developing Drosophila embryos where tissue recoil following laser a

291 in the first mitotic divisions of the early Drosophila embryo, where groups of epithelial cells sync

292 Zelda (Zld) plays such a role in the Drosophila embryo, where it has been shown to control th

293 eloping a barbed end incorporation assay for Drosophila embryos, which revealed barbed end enrichment

294 tial for it to direct myoblast fusion in the Drosophila embryo, while the conserved DCrk-binding prol

295 along the dorsal-ventral (DV) axis of early Drosophila embryos, while repressors establish ventral b

296 Bicoid-dependent transcription in the early Drosophila embryo with high temporal resolution, allowin

297 ets, performing ChIP-seq for the TF Twist in Drosophila embryos with different experimental fragment

298 e amnioserosa cells during dorsal closure in Drosophila embryos with in vivo imaging of green-fluores

299 Drosophila embryos with mutations in the JAK/Stat ligand

300 Drosophila embryos with trr alleles encoding catalytic m