ライフサイエンスコーパス: E. coli

1 E. coli and Salmonella are two of the most common bacter

2 E. coli cells expressing FliC(N87K) sensed ascending a c

3 E. coli DeltaL YA constitutively co-expressing alpha-L-f

4 E. coli RNA polymerase initiates transcription more effi

5 Shedding of mcr-1 E. coli by small gull flocks followed a lognormal curve

6 detection and from 1 to 4 x 10(4) CFU mL(-1) E. coli quantification.

7 the ejection of a representative set of 122 E. coli proteins we find a greater than 1000-fold variat

8 temporally and clinically diverse set of 907 E. coli isolates, including 722 uropathogenic E. coli (U

9 se pair resolution dissection of more than a E. coli promoters in 12 growth conditions.

10 d the highest antimicrobial activity against E. coli, S. aureus, and S. typhi in in vitro antimicrobi

11 ocapsules had antimicrobial activity against E. coli, which could be extended to develop active packa

12 X) for fishing out specific aptamers against E. coli Shiga toxin subtypes viz., stx1 & stx2 via epito

13 istance capacity of K. michiganensis against E. coli, supporting the idea that nutrient competition i

14 ulsions, and chlorhexidine solutions against E. coli and S. aureus.

15 e fab genes of FA synthesis thereby allowing E. coli to have its cake (acyl chains for phospholipid s

16 Instead, serine alters E. coli's 1C-metabolism, reduces the provision of nucleo

17 es of tRNA(fMet) from the genome afforded an E. coli strain in which the efficiency of non-canonical

18 tability and its interaction with SecA in an E. coli mutant devoid of CL.

19 ) , oppA3(Ct) ) along with oppBCDF(Ct) in an E. coli mutant lacking the Opp transporter and determine

20 eroaggregative Escherichia coli (EAEC) is an E. coli pathotype associated with diarrhea and growth fa

21 In this system, an E. coli recording strain is exposed to a microbial sampl

22 low cost commercial microelectrodes with an E. coli specific antibody.

23 (Gfp)-tagged AR plasmid (pRP4-gfp) within an E. coli host (EcoFJ1) in the liquid phase and biofilms i

24 s on downstream genes in EAEC strain 042 and E. coli K-12 strain DH5alpha, which lacks the AggR regul

25 quently contaminated with E. coli (69%), and E. coli levels were the highest during the wet season.

26 dia (blank broth, Staphylococcus aureus, and E. coli).

27 assay was performed on Ab-modified MBs, and E. coli could be quantified in tap water and milk.

28 obacter baumannii, Klebsiella pneumoniae and E. coli.

29 We show that B. subtilis and E. coli gyrases are proficient DNA-stimulated ATPases an

30 midis, M. luteus, E. hirae, B. subtilis, and E. coli.

31 ere collected and the isolates identified as E. coli (n = 381) were selected.

32 do not) distinguish UTI- from ASB-associated E. coli strains.

33 t exhibited effectiveness against S. aureus, E. coli, and S. typhimurium, with minimum inhibitory con

34 The Gram-negative bacteria E. coli and P. aeruginosa were particularly sensitive to

35 essed by tracking of particles and bacteria (E. coli and E. cloacae) with developmental age and expos

36 o suggesting a recalcitrant mismatch between E. coli physiology and growth on citrate.

37 truct an eCRISPR based redox conduit in both E. coli and Salmonella enterica.

38 applied the Stabilized Peptide Evolution by E. coli Display technique to develop disrupters of the t

39 des protection against systemic infection by E. coli.

40 at the discrimination between RNA ligands by E. coli ProQ and Hfq depends both on positive determinan

41 DHMA that is generated in vivo by E. coli is expected to be a racemic mixture of the (R) a

42 el constrained by a large set of single-cell E. coli flagellar synthesis data from different strains

43 6.8 mum, three bacteria strains (B. cereus, E. coli, and S. enterica) and a yeast cell (S. cerevisia

44 We also found that 12.8% of broiler chicken E. coli isolates and 7.61% of layer chicken isolates car

45 On the other hand, 51.09% of layer chicken E. coli isolates were MDR, with 3, 4 or 5 ARGs detected

46 the antibody against a panel of 86 clinical E. coli ST131 O25:H4 isolates revealed 4 binding phenoty

47 Results were interpreted according to CLSI E. coli breakpoints, with 49.0 to 85.8% considered susce

48 unsaturation of lipids in Escherichia coli (E. coli) and Acinetobacter baumannii (A. baumannii).

49 ctivation of Gram-negative Escherichia coli (E. coli) and Gram-positive Enterococcus durans (E. duran

50 bition zone method against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), which de

51 ment platform comprised of Escherichia coli (E. coli) and transgenic zebrafish embryos, we are able t

52 Antibiotic-resistant Escherichia coli (E. coli) are common in retail poultry products.

53 , sensitive and label-free Escherichia coli (E. coli) detection utilizing interferometric reflectance

54 ase in dairy industry, and Escherichia coli (E. coli) is one of the major causative pathogens.

55 ed 711 proteoforms from an Escherichia coli (E. coli) proteome consuming only nanograms of proteins.

56 Most Escherichia coli (E. coli) strains do not cause disease, naturally living

57 Escherichia coli (E. coli) was engineered to catalyse the cleavage of 2'-F

58 teps of rRNA processing in Escherichia coli (E. coli) were described several decades ago, the enzymes

59 n (DIP) Human, Drosophila, Escherichia coli (E. coli), and Caenorhabditis elegans (C. elegan) dataset

60 dark inactivate planktonic Escherichia coli (E. coli).

61 %), with lower reductions for the coliforms (E. coli 57% and Klebsiella 49%).

62 Although commensal E. coli expressing Pic degraded MUC2, it did not show im

63 ay impact plasmid transfer between commensal E. coli and S. sonnei.

64 strategy may also be relevant for commensal E. coli diminishing the S. Typhimurium infection.

65 Twenty-five percent of the commensal E. coli strains harbored mcr-1 genes.

66 control protease naturally absent in common E. coli expression strains, drastically reshapes the mut

67 en the two constructs suggest a more compact E. coli MscL at the membrane inner-leaflet, as a consequ

68 e apparent for each manufacturer for control E. coli strains.

69 bolA potentiated carbapenem efficacy in CRE E. coli, whereas inhibition of the genes flhC and ygaC c

70 ut was nearly eliminated in a ClpB-deficient E. coli strain, which demonstrates a significant selecti

71 howed that FA synthesis primarily determines E. coli cell size.

72 ence of mcr-1 gene among genetically diverse E. coli populations from broiler chickens in Bangladesh

73 PCR profiles and WGS analysis showed diverse E. coli population carrying multiple antimicrobial resis

74 Administration of RvD5n-3 DPA during E. coli-initiated inflammation regulated neutrophil traf

75 anic carbon source, pointing to S. elongatus-E. coli K-12 as the most active community.

76 Expression of 20 CCM genes enabled E. coli to grow by fixing CO(2) from ambient air into bi

77 ich are then decoded by gelatin-encapsulated E. coli.

78 By engineering E. coli cells carrying individual and compensatory mutat

79 on with exogenous hydrogen peroxide enhanced E. coli growth through AppBCX-mediated respiration in a

80 Enteroaggregative E. coli (EAEC) are a major cause of diarrhoea worldwide.

81 Here we report that histone H2A enters E. coli and S. aureus through membrane pores formed by t

82 i-Mg-3wt% Zn) that can selectively eradicate E. coli while not harming the survival rate, development

83 portance of culture media for detecting ESBL E. coli.

84 roducibility and detection of potential ESBL E. coli from poultry cecal (n = 30) and water (n = 30) s

85 From ceca and water, potential ESBL E. coli isolates were only confirmed from MacConkey agar

86 ely detecting and quantifying potential ESBL E. coli MacConkey agar from eight manufacturers, represe

87 d virulence genes were added to the existing E. coli VirulenceFinder database.

88 By exposing E. coli that do not perform lysis to the DNase colicin,

89 nes encoding aggregative adherence fimbriae, E. coli common pilus, flagellin and EAEC heat-stable ent

90 suppressed growth and colonisation by focal E. coli but also prevented it from evolving antibiotic r

91 mples from all three human donors, our focal E. coli strain only evolved antibiotic resistance in the

92 city rates of 100% for all classes, both for E. coli and for K. pneumoniae.

93 anchors and Z-ring regulators described for E. coli.

94 nsing, we have developed an immunosensor for E. coli detection by modifying low cost commercial micro

95 The ATR system is important for E. coli survival in the mouse intestine and for producti

96 CA072 for B. cenocepacia J2315 and pESBL for E. coli O104:H4.

97 Curli expression is required for E. coli to exacerbate alphaSyn-induced behavioral defici

98 Four E. coli strains (NC11, ATCC 25922, CM-13457, and CM-1045

99 of L-Asn by the type II L-asparaginase from E. coli (EcAII), but that work was limited to just one e

100 Ribosome profiling data from E. coli reveals that the presence of slowly ejecting seq

101 d oxidation-induced abasic sites in DNA from E. coli treated with a sublethal dose of hydrogen peroxi

102 2-oxobutanoate hydroxymethyltransferase from E. coli (KPHMT) and variants thereof.

103 died how frameshift-inducing stem-loops from E. coli dnaX mRNA and the gag-pol transcript of Human Im

104 e report the crystal structure of MlaFB from E. coli, the cytoplasmic portion of the larger MlaFEDB A

105 ous bacteria could obtain these vectors from E. coli through several mechanisms of horizontal gene tr

106 We demonstrate that the YbeY from E. coli and S. meliloti can reciprocally complement the

107 city depends on the presence of a functional E. coli trxA allele and T7 RNA polymerase-driven express

108 Here, Q8 deficiency impaired E. coli growth at low osmotic pressure and rendered grow

109 In E. coli, experimental studies performed over the past si

110 In E. coli, ppGpp inhibits purine nucleotide synthesis by t

111 In E. coli, this is mediated by the proteins DsbC and DsbD.

112 and membrane lipid cardiolipin accumulate in E. coli cells cultivated at high osmotic pressure.

113 lycan fragments (tri-diaminopimelic acid) in E. coli and in C. trachomatis These findings suggest tha

114 dentified mode of tolerance to ampicillin in E. coli.

115 ulations and a synthetic biology approach in E. coli, we find that the TF gene and its target genes h

116 oglycoside bacteriostasis and bactericide in E. coli.

117 duction of C. difficile vaccine candidate in E. coli by using restricted DO growth.

118 tage of transcripts that are Np(4)-capped in E. coli, clear evidence for Np(4) cap acquisition by Np(

119 trated that 2,7-anhydro-Neu5Ac catabolism in E. coli depended on YjhC and on the predicted sialic aci

120 rphogen-induced mutual inhibition circuit in E. coli populations and show that mutual inhibition alon

121 evelopment of high-accumulating compounds in E. coli, and a general blueprint for the conversion of G

122 major mechanism of translational coupling in E. coli.

123 sm by which spacer orientation is defined in E. coli.

124 ry of single non-essential gene deletions in E. coli str.

125 olog from Hemophilus influenzae expressed in E. coli cells also reversibly binds a [2Fe-2S] cluster t

126 However, when co-expressed in E. coli LiGPPS.LSU and LiGPPS.SSU1 formed an active hete

127 nents followed by heterologous expression in E. coli and spectroscopic analysis of the purified produ

128 proves multiplex editing by 5- to 10-fold in E. coli, while PapRecT enables efficient recombineering

129 achycardia, and compromised lung function in E. coli-exposed mice.

130 ely removes the [2Fe-2S] cluster from Fur in E. coli cells, suggesting that Fur senses the intracellu

131 yejM was discovered as an essential gene in E. coli and S. typhimurium that plays a critical role in

132 expression of citrate fermentation genes in E. coli under anaerobic conditions.

133 r ppGpp to inosine-guanosine kinase (Gsk) in E. coli modulates the levels of the key metabolite phosp

134 As also conferred the ability to bind Hfq in E. coli cells, as measured using a three-hybrid assay.

135 first 5' to 3' RNA exonuclease identified in E. coli.

136 In contrast, the specific insertions in E. coli and mycobacterial gyrase subunits appear to prev

137 compound that accumulates to a high level in E. coli, is effective against Gram-negative clinical iso

138 Pol IV is expressed at increased levels in E. coli cells exposed to exogenous DNA damaging agents,

139 larger model of central carbon metabolism in E. coli, and compared each framework's ability to recapi

140 introduction of the acp3U-47 modification in E. coli tRNAs is promoted by the presence of the m7G-46

141 the knob-into-hole and WT IgG4 molecules in E. coli.

142 get RNAs differing by a single nucleotide in E. coli and resolve single epitranscriptomic marks in vi

143 aldoxime dehydratase (OxdB) overexpressed in E. coli.

144 tood, because MK and DMK are also present in E. coli Here, we established that UQ(9) is the major qui

145 laccase from T. thermophilus was produced in E. coli, and the effect of Cu(2+) on its electroactivity

146 ns were expressed as recombinant proteins in E. coli.

147 ptive response and repair of S (p)-Me-PTE in E. coli, however, was essential for the generation of th

148 ntributes to mutagenesis of S (p)-Me-PTEs in E. coli.

149 ndent manner has been discovered recently in E. coli Its physiological relevance is not yet understoo

150 tems are known to control acid resistance in E. coli, enabling the bacteria to survive under acidic c

151 does not confer antimicrobial resistance in E. coli, highlighting the importance of verifying protei

152 udy defines an antifolate stress response in E. coli and links its associated metabolites to a major

153 aCl by KGlu, the primary cytoplasmic salt in E. coli, results in a decrease of the diffusion coeffici

154 ntally for many different nutrient shifts in E. coli, as well as for other respiro-fermentative micro

155 hosphate buffered saline (PBS) and spiked in E. coli cell lysate.

156 initial adaptive response to N starvation in E. coli These results serve as a paradigm to demonstrate

157 f ribosome recycling on protein synthesis in E. coli.

158 the effectiveness of antibiotic treatment in E. coli-induced myositis and a clinically relevant S. au

159 icient expression of the designed vaccine in E. coli expression system.

160 LC, by recombinantly expressing variants in E. coli.

161 pC as an alternative receptor when infecting E. coli.

162 000+ intact proteoforms from 5 mug of intact E. coli cell lysate in 10 online-collected fractions.

163 nd genotypes observed among the investigated E. coli isolates.

164 lian cell-expressed receptor compared to its E. coli-expressed counterpart, due to contributions from

165 In total, 48 of the 55 known E. coli ribosomal proteins are identified as 84 unique p

166 Mice were inoculated with live E. coli intratracheally (i.t.) with or without adenosine

167 ively characterize gene repression in living E. coli by a collection of individual TALED loops with s

168 ggested that mutations removing the CTT make E. coli less susceptible to sodium azide at subinhibitor

169 ve a promising in vitro activity against MDR-E. coli.

170 eria with costained nucleoids and membranes (E. coli) on surfaces with nanopillars.

171 trated that adenosine or ATPgammaS mitigates E. coli-induced ALI in mice and may be useful as an adju

172 Conversely, in a vaginal colonization model, E. coli are detected inside vaginal cells and the urinar

173 dissociation of a natural protein nanocage, E. coli bacterioferritin (Bfr), using synchrotron radiat

174 gram-positive (S. aureus) and gram-negative (E. coli) bacteria on solid and porous surfaces.

175 d ground beef can also contain nonadulterant E. coli strains, regular PCR cannot confirm whether the

176 s are carried by adulterant or nonadulterant E. coli serogroups.

177 consume 3.6-4.9 log(10) most probable number E. coli/day.

178 4 mug/ml cefotaxime, where 45% and 16.6% of E. coli isolates phenotypically expressed ESBL productio

179 re, we systematically explore the ability of E. coli to harness underground metabolism to compensate

180 The amount of E. coli ingested by children and the predominant pathway

181 The binding of E. coli to the M13 phage on the cytosensor surface incre

182 Hence, inflammation-induced blooms of E. coli LF82 are significantly blunted when amino acids-

183 oteins that bind to the secondary channel of E. coli RNA polymerase (RNAP), such as GreA, GreB or Dks

184 id not contain any major chemoattractants of E. coli, in contradiction to some previous reports, whic

185 identification and quantitative detection of E. coli are of great importance for bovine mastitis cont

186 throughput approach for the determination of E. coli endotoxin after only 60 s, with a limit of detec

187 In DH5alpha, aar affected expression of E. coli genes in some cases via H-NS and in some cases i

188 has also been shown to affect expression of E. coli housekeeping genes, including H-NS, a global reg

189 ecently characterised a low-activity form of E. coli transketolase, TK(low), which also binds the cof

190 tion was restored during prolonged growth of E. coli at high osmotic pressure.

191 ll wall, and eventually growth inhibition of E. coli K-12.

192 Investigations of E. coli cell size determinants showed that FA synthesis

193 The DBeQ-induced loss of E. coli proliferation was exacerbated by heat shock but

194 d translocation across the inner membrane of E. coli.

195 mase) DeltadapF (epimerase) double mutant of E. coli rescues the d-glutamate auxotrophic defect.

196 e re-examined the experimental parameters of E. coli in-cell NMR and found that the detectability and

197 ereas nonlytic toxins leave large patches of E. coli alive.

198 ds, food, and objects as primary pathways of E. coli ingestion and emphasize the value of intervening

199 by children and the predominant pathways of E. coli ingestion were unchanged by the water, sanitatio

200 re we show that an assay in the periplasm of E. coli linking aggregation directly to antibiotic resis

201 In the presence of E. coli, the nematode's neurons signal via TGFbeta-insul

202 The prevalence of E. coli was 30% (n = 48) distributed in 8 serogroups (40

203 en-starved bacteria as a biological probe of E. coli cell function during nitrogen starvation, we dem

204 filtrating CD45(+) cells in the prostates of E. coli- or phosphate-buffered saline-treated mice.

205 Results indicated the recovery of E. coli 13457 from four MacConkey agar manufacturers was

206 ocytosis, thereby facilitating resolution of E. coli-evoked lung injury.

207 foci have a role in the adaptive response of E. coli to long-term nitrogen starvation.

208 The global responses of E. coli cells to m-Tyr were assessed by RNA-seq, and >50

209 of m-Tyr toxicity, we utilitized a strain of E. coli that expresses a QC-defective PheRS.

210 le microbial community with three strains of E. coli that cyclically interact through (i) the inhibit

211 ity of the proteomes of sequenced strains of E. coli.

212 has been described in a number of strains of E. coli.

213 Docking of ATP on a structure of E. coli DnaA, modeled upon the crystallographic structur

214 Here we present nine cryo-EM structures of E. coli ATP synthase to 3.1-3.4 angstrom resolution, in

215 Here, we report cryo-EM structures of E. coli sigma(28) -dependent transcribing complexes on a

216 mice demonstrated baseline translocation of E. coli into the liver and spleen and were more suscepti

217 -a nutrient that supports the growth of only E. coli-to bi-colonized gnotobiotic mice abolished the c

218 as compared to control in both germ-free or E. coli gut microbiota states was used to quantitate pat

219 Two other E. coli proteins that contain SecA-like MBDs, YecA and Y

220 K. michiganensis generally outcompeted E. coli in vitro, but in vivo administration of galactit

221 ins) and outside (extraintestinal pathogenic E. coli, or ExPEC).

222 he ETT2 locus in strains of human pathogenic E. coli, we carried out genomic sequencing of 162 isolat

223 When expressed in non-pathogenic E. coli, this pathway confers immunity against bacteriop

224 The majority of pathogenic E. coli contain elements of a genetic locus encoding ETT

225 s essential for the attachment of pathogenic E. coli to the intestinal host cell.

226 ccumulation and capture of motile pathogens (E. coli) within the microtrap structure, while the inter

227 ls, showed increased killing of phagocytosed E. coli and M. smegmatis Polyphosphate inhibited phagoso

228 man intestinal organoids to genotoxic pks(+) E. coli by repeated luminal injection over five months.

229 ay facilitate transmission of mcr-1 positive E. coli to humans and livestock through fecal contaminat

230 ls are readily colonized with mcr-1 positive E. coli, their shedding patterns, transmission among con

231 imipenem activity against an NDM-1-producing E. coli clinical strain.

232 The carriers had 96 ESBL-producing E. coli isolates, 51% exhibiting a molecular pathotype:

233 Half of all travel-acquired ESBL-producing E. coli strains qualified molecularly as pathogens.

234 teep gradients with wide temperature ranges, E. coli aggregated at intermediate temperatures, with ma

235 re gradients with narrow temperature ranges, E. coli tended to aggregate near a sidewall of the gradi

236 at propionylation of Lys280 on AdeT1 renders E. coli cells more resistant to erythromycin.

237 udies, the M. tuberculosis Tam also replaced E. coli BioC both in vivo and in vitro and complemented

238 ategy to help reduce ciprofloxacin-resistant E. coli in cattle within the United States.

239 fecal prevalence of ciprofloxacin-resistant E. coli.

240 le fecal shedding of ciprofloxacin-resistant E. coli.

241 alence of 3G-C and fluoroquinolone-resistant E. coli was 4% and 10%, respectively.

242 iated with the spread of multidrug-resistant E. coli phenotypes responsible for device- and procedure

243 the three protoxins are acylated in the same E. coli cell background by each of the CyaC, HlyC, and R

244 onize new niches, interrogation of sequenced E. coli O157:H7 genomes showed a high level of CycA cons

245 ce of any redox indicators, allowed a single E. coli cell detection and from 1 to 4 x 10(4) CFU mL(-1

246 ne control strains and (ii) 288 human-source E. coli strains classified by PCR as ExPEC and non-ExPEC

247 In this study, E. coli BL21 was engineered to express the zntR, ribB, a

248 ive treatment of ceftriaxone non-susceptible E. coli and Klebsiella.

249 ng a programmable dCas9 represses a targeted E. coli gene in the mammalian gut.

250 ed T3SS but in addition a second T3SS termed E. coli T3SS 2 (ETT2) has been described in a number of

251 activity against 2,7-anhydro-Neu5Ac and that E. coli could catabolize 2,7-anhydro-Neu5Ac.

252 We also show that E. coli IGPS, at an even lower rate, can produce IGP fro

253 The E. coli K15 serotype has been identified as both an ente

254 stem can be used to detect and associate the E. coli serogroup-specific gene with major virulence gen

255 in phosphatase, significantly attenuated the E. coli-induced compromise of lung function.

256 dge, this is the first report concerning the E. coli secondary bacterial infections following the FMD

257 ete GEM that has been developed to date: the E. coli GEM.

258 nerates a multitude of sequence ions for the E. coli ammonia channel (AmtB), provides improved locali

259 Our findings implicate the E. coli host 3'-5' exonucleases DnaQ and ExoT in spacer

260 sent in eukaryotic enzymes but absent in the E. coli homolog.

261 Fe-2S] cluster in Fur protein is ~31% in the E. coli iscA/sufA mutant cells and is decreased to ~4% i

262 Multidrug resistance in the E. coli isolates collected (n = 236) was common, with th

263 BPs, while only one, OppA, is encoded in the E. coli opp operon.

264 We present cryo-EM studies of the E. coli enzyme that show how asymmetric hexameric rings

265 ore, the detectability and resolution of the E. coli in-cell NMR spectra correlated with the soluble

266 Our ~3.5 angstrom cryo-EM structure of the E. coli MCE protein LetB reveals an ~0.6 megadalton comp

267 he geometric and electronic structure of the E. coli periplasmic molybdenum-dependent methionine sulf

268 d demonstrates remarkable versatility of the E. coli translational machinery for initiation with ncAA

269 d to be more stable, more antigenic than the E. coli protein, and form higher-order oligomers.

270 Both new approaches showed that the E. coli ammonium transporter AmtB prefers phosphatidylgl

271 Here we show that the E. coli Bam complex catalyzes the efficient assembly of

272 ctor pSF-OXB15-p450camfusion showed that the E. coli cells died after five days but a variety of bact

273 ted RNA and is structurally unrelated to the E. coli McrB DNA-binding domain.

274 ing of the motor was almost identical to the E. coli W3110 strain, which is a derivative of K-12 and

275 Within the E. coli population, distinct invasive UPEC lineages emer

276 e marrow-derived dendritic cells compared to E. coli LPS.

277 ical signs of lung injury in mice exposed to E. coli.

278 TA3, and IRF4) at 18 hours after exposure to E. coli were identified to be differentially regulated b

279 ther goat's mammary gland immune response to E. coli lipopolysaccharide (LPS) could be conditioned by

280 ACSL1 levels were elevated in response to E. coli treatment, and macrophage-expressed ACSL1 was in

281 iption-coupled repair in a manner similar to E. coli.

282 were replaced by alanine is highly toxic to E. coli cells.

283 e TSP that confers phage specificity towards E. coli O157:H7.

284 e overflow were accurately simulated for two E. coli strains.

285 ved antibacterial activity against wild-type E. coli.

286 Here, we decode a previously unknown E. coli metabolic pathway that produces a family of hybr

287 stingly, we find that in B. subtilis, unlike E. coli where multiple enzymes have a biochemical activi

288 When assigning sites of unsaturation, E. coli was found to contain all unsaturation elements a

289 ormed by MICP starting from single ureolytic E. coli MJK2 cells in 25 um diameter drops.

290 . coli isolates, including 722 uropathogenic E. coli (UPEC) isolates.

291 vious studies established that uropathogenic E. coli - the primary cause of urinary tract infections

292 inflammatory response against uropathogenic, E. coli-induced, acute pyelonephritis.

293 Finally, using E. coli mutants and complementation growth assays, we de

294 mpound that accumulates intracellularly when E. coli is exposed to high concentrations of extracellul

295 iDe to in vivo metatranscriptomic data where E. coli was present at high abundances, and found that o

296 owledge, this level of sensitivity for whole E. coli detection is unprecedented in label-free biosens

297 Acidosis is associated with E. coli induced pyelonephritis but whether bacterial cel

298 er samples were frequently contaminated with E. coli (69%), and E. coli levels were the highest durin

299 noculating petroleum-polluted sediments with E. coli carrying the vector pSF-OXB15-p450camfusion show

300 A mutant cells and is decreased to ~4% in WT E. coli cells.