ライフサイエンスコーパス: EC number

1 matic function (identical Enzyme Commission, EC, number).

2 ons that are annotated with the same partial EC number.

3 y because of the ambiguous nature of partial EC numbers.

4 0% sequence identity have entirely identical EC numbers.

5 s on functional motifs of enzymes to predict EC numbers.

6 as a neural network architecture to predict EC numbers.

7 is split according to Enzyme Classification (EC) number.

8 first three digits of the enzyme commission (EC) number.

9 lytic functions using the Enzyme Commission (EC) number.

10 ic functions described by Enzyme Commission (EC) numbers.

11 re in the same classes of Enzyme Commission (EC) numbers.

12 281 +/- 94 pM, hypoxia-CM) and no change in EC number (35.6 +/- 5.9 x 10(3) ECs/cm2, normoxia-CM ver

13 similarity to each other were found for 105 EC numbers (a total of 243 distinct proteins).

14 ; however, to transfer all four digits of an EC number, above 60% sequence identity is needed to have

15 lassification of putative Enzyme Commission (EC) numbers across this proteome, and the computational

16 in each cluster, the proteins have the same EC number and all sequences are similar; (ii) selecting

17 duced the total apoptotic cell and apoptotic EC number and promoted the formation of blood vessels du

18 the Clusters of Orthologous Groups (COG) to EC numbers and a six-fold increase in mappings from COG

19 ty of protein functions - Enzyme Commission (EC) numbers and Gene Ontology (GO) terms - directly from

20 id annotation of EST datasets with GO-terms, EC-numbers and KEGG-pathways.

21 sts of species-specific enzymatic reactions (EC numbers) and generates a matrix of the potential comp

22 ere as sharing the first three digits of the EC number); and (ii) transformational analogues which ca

23 in Pfam family PF00294, a previously orphan EC number; and 3) epimerization of d-tagatose 6-phosphat

24 n-function relationships; (1) for sequences, EC numbers are typically assigned to whole sequences rat

25 zymes, as defined via the Enzyme Commission (EC) numbers, are likely to interact with a given query m

26 n of the OFT: alk5-/- OFTs exhibit increased EC numbers as well as extracellular matrix (ECM) and SMC

27 can be queried via Swiss-Prot identifier and EC number, as well as by PDB code.

28 lactate to L-pyruvate by lactate oxidase (no EC number assigned) and the decarboxylation of L-pyruvat

29 atalyse exactly the same reaction (identical EC numbers), but may use different mechanisms.

30 creases in insulin and VEGF-induced pAkt and EC numbers by >50% without changes in angioblasts versus

31 n of EC, although it blocked the decrease in EC number caused by the removal of basic fibroblast grow

32 creening covers all seven enzyme commission (EC) number classes, setting the stage for widespread use

33 Consequently, the ability to predict EC numbers could substantially reduce the number of un-a

34 These data indicate that (1) increased EC number does not promote, but actually impairs beta ce

35 2 MG1655 genome, DeepECtransformer predicted EC numbers for 464 un-annotated genes.

36 n optional associated Enzyme Classification (EC) number for each reaction.

37 ne Ontology (GO) terms or Enzyme Commission (EC) numbers for AF2-predicted structures and (iii) pocke

38 onal annotations, such as enzyme commission (EC) number, for less-studied proteins or those with prev

39 entries, and covers approximately 30% of all EC numbers found in PDB.

40 dentify promiscuous enzymes with two or more EC numbers-functions that we demonstrate by systematic i

41 searching by keyword combinations, PDB IDs, EC numbers, GI numbers, LocusLink ID, taxonomy, gene ont

42 s to refer to the concepts of interest, e.g. EC numbers, GO and SBO identifiers.

43 old to transfer the first three digits of an EC number; however, to transfer all four digits of an EC

44 Increased angioblasts and EC numbers in GT of ECIRS1 mice were due to proliferatio

45 Fams outperformed even the carefully curated EC numbers in terms of agreement of binding site residue

46 Remarkably, when the SHF-derived EC number is decreased, PAA development can be rescued b

47 Overall, EC number is fairly well conserved within a superfamily,

48 ngle and multi-domain proteins, variation in EC number is rare above 40 % sequence identity, and abov

49 ion of gene functions for genes with partial EC numbers is inconsistent with the activities implied b

50 We find that use of the Enzyme Commission (EC) numbers is necessary to enable efficient and accurat

51 Heparinase II (no EC number) is one of three lyases isolated from Flavobac

52 We find that although the EC number may differ, the reaction chemistry of these se

53 d individual EC areas, rather than increased EC number or proliferation.

54 e the Gene Ontology (GO); Enzyme Commission (EC) numbers; pathways from UniPathway; human phenotype o

55 despite a lack of clarity in the literature, EC number prediction is not a single problem; the challe

56 ECPICK is a reliable EC number prediction tool to identify protein functions

57 were identified for 45 of the 951 four-digit EC numbers present within the CSA and about half of thes

58 The mappings to EC numbers show a very high precision (99.8%) and recall

59 interpretation of partial Enzyme Commission (EC) numbers such as '1.1.1.-'.

60 achine models to make overall assignments of EC number to an accuracy of 35% with the top-ranked pred

61 assignment of genes annotated with a partial EC number to many or all biochemical reactions that are

62 earning-enabled enzyme annotation) to assign EC numbers to enzymes with better accuracy, reliability,

63 enzymes with the same enzyme classification (EC) number using sensitive, iterative sequence database

64 rustworthy predictions of enzyme commission (EC) numbers with data-driven domain-relevant evidence, w