ライフサイエンスコーパス: EC

1 EC Hif-2alpha-knockout mice demonstrated lower levels of

2 EC loss rates were 43.8% in F-DMEK and 38.0% in M-DMEK a

3 EC molecular classification should be incorporated in th

4 EC neurons also show striking spatial representations as

5 EC-specific ablation of Gja1 restores beta-cell expansio

6 EC-specific PKD2 knockout elevated blood pressure in mic

7 ECs also had elevated REG3alpha levels compared to contr

8 ECs are presumed to be devoid of water because they form

9 ECs between PVs and other adjacent structures are freque

10 ECs reduce the acute and chronic success of PV isolation

11 tor agonist described so far (E(max) = 118%, EC(50) = 0.24 muM, K(D) = 19.6 nM; inactive at autotaxin

12 ng the European Commission Decision 2002/657/EC.

13 onstrate that hAPP overexpression aggravates EC-Tau aggregation and accelerates pathological tau spre

14 SOCS3 within EVs serves as a brake on airway EC responses during allergic inflammation, but is impair

15 in allergic inflammatory responses in airway ECs.

16 ts the synthesis of RA from type II alveolar ECs to suppress excessive activation of innate lymphoid

17 tive regulator of ST2 expression in alveolar ECs to generate retinoic acid (RA) and supports the synt

18 HFI-419 on insulin-regulated aminopeptidase (EC 3.4.11.3) in the rat neocortex.

19 Shared genomic regions among EC levels were identified on BTA 2 and 14, harboring can

20 of the hexosamine D-mannosamine (ManN) as an EC mitogen and survival factor for bovine and human micr

21 SPR519 exhibits an EC(50) of low sub-micromolar range among various tested

22 In addition, 84 had an EC(50) of 942 nM in the [(35)S]GTPgammaS binding assay u

23 n of the sensor as a working electrode in an EC setup.

24 f HEK293 cells expressing human ACE2 with an EC(50) of 0.3 ug/mL.

25 dide transport activity remains high with an EC(50) of 0.37 mum.

26 ates potent in vivo target occupancy with an EC(90) of 1.6 mg/kg and dose-dependent efficacy in rat c

27 played the highest activity, with IC(50) and EC(50) values in the lower micromolar range in biochemic

28 c variants (PVs) among patients with CRC and EC.

29 talloproteinase-9) as well as between DS and EC for biomarkers of inflammatory mediators (receptor fo

30 Finally, we demonstrate effects of ISEMF and EC co-culture on patient-derived human intestinal epithe

31 rs and at later times they co-express MC and EC-specific proteins and maintain graft patency.

32 on to the evaluation of Michaelis-Menten and EC(50)/IC(50) kinetic parameters, as well as the results

33 ns from large point sources and nitrates and EC emissions from mobile sources contributed the largest

34 y bone marrow-derived mast cells (BMMCs) and ECs from WT and Fn14(-/-) or TWEAK(-/-) mice were studie

35 ood flow, increased proliferation of PCs and ECs, and attenuated loud sound-caused loss in endocochle

36 ction and gap junction between pericytes and ECs are downregulated by EP-4 and EP-1-dependent mechani

37 ional connectivity between the anterolateral EC and the anterior-temporal (AT) memory network appears

38 ioassay showed a linear increase of apparent EC with increasing lipid fraction.

39 d a mild antioxidant activity by DPPH assay (EC(50) = 3940 mg/L), higher than that of 2-IPMA (EC(50)

40 ngly, many neutrophils that migrated between EC junctions were able to rejoin the blood circulation.

41 stent exposure-response relationship between EC exposure and lung cancer in men.

42 In men, exposure response between EC and lung cancer was observed: odds ratios ranged from

43 In both EC and PEC methods effecting experimental parameters wer

44 Memory also appears to be affected by EC tau in the absence of Abeta, which may be less clinic

45 of the Kif11 CKO phenotype to that caused by EC-specific reductions in beta-catenin signaling.

46 whereas maximum inhibition of HSA and PPA by EC was reached only after 45 to 60 min of incubation.

47 d, diversity hits a plateau (as predicted by EC).

48 Human carbonic anhydrase (CA; EC 4.2.1.1) isoforms II and VII are implicated in neuron

49 for women with high-risk endometrial cancer (EC).

50 nal burden-high (TMB-H) endometrial cancers (ECs).

51 ely, a subset of angiogenic venous capillary ECs and respective resident endothelial progenitors appe

52 Car4 ECs are specifically lost upon epithelial Vegfa deletion

53 upon epithelial Vegfa deletion; without Car4 ECs, the alveolar space is aberrantly enlarged despite t

54 l exhaust characterized by elemental carbon (EC) concentrations.Methods: We used a quantitative EC jo

55 propose the additions of ethylene carbonate (EC) to the imaging buffer, sequence repeats to the docki

56 arteries of PAH patients harboured CD117(+) ECs.

57 in vitro three-dimensional endothelial cell (EC) and PC co-culture model, transformed PCs induced thi

58 tigate the role of ORP2 in endothelial cell (EC) cholesterol and PI(4,5)P(2) distribution, angiogenic

59 capillary nonperfusion and endothelial cell (EC) loss.

60 is required for a distinct endothelial cell (EC) population in the mouse lung.

61 ted murine and human liver endothelial cell (EC) populations into liver sinusoidal endothelial cells

62 lk between tumor cell- and endothelial cell (EC)-secreted IL6 on HNSCC growth and the CSC fraction.

63 armofur inhibits viral replication in cells (EC(50) = 24.30 muM) and is a promising lead compound to

64 otent activation of Vgamma9/Vdelta2 T-cells (EC(50) ranging from 5 fM to 73 nM), which translated int

65 Pulmonary endothelial cells (ECs) are an essential component of the gas exchange mach

66 Endothelial cells (ECs) are highly glycolytic and generate the majority of

67 Endothelial cells (ECs) are widely heterogenous depending on tissue and vas

68 Endothelial cells (ECs) display considerable functional heterogeneity depen

69 Endothelial cells (ECs) display remarkable plasticity during development be

70 e-RGD hydrogel laden with endothelial cells (ECs) for further analysis.

71 en inflammatory cells and endothelial cells (ECs) is a crucial step in vascular inflammation.

72 dentified a population of endothelial cells (ECs) present early in HIO differentiation that declines

73 s highly enriched in lung endothelial cells (ECs) throughout development.

74 erize subclasses of brain endothelial cells (ECs) under both normal conditions and after deletion of

75 Endothelial cells (ECs) within the BRB/BBB are tightly coupled, express hig

76 primary receptor CCR10 in endothelial cells (ECs).

77 tion of Kif11 in vascular endothelial cells (ECs).

78 croRNA (miR), miR-15a, in endothelial cells (ECs).

79 tory signaling in alveolar epithelial cells (ECs) by transcellular delivery of suppressor of cytokine

80 r posterior face and quiescent Escort Cells (ECs) to their anterior.

81 ermeability controlled by endothelial cells [ECs]).

82 ults suggested that Saccharomyces cerevisiae EC-1118 was suitable for fermentation of longan juice su

83 ed 10 times more efficiently than chlorides (EC(50) =0.47 mum).

84 tin landscapes of acutely isolated mouse CNS ECs.

85 The co-EC Study (Enhancing care and treatment among HCV/HIV co-

86 ng treatment, cultured for Escherichia coli (EC) and DNA extracted.

87 criteria defined by the European Commission (EC) in Commission Decision no.

88 report the cryo-EM structure of the complete EC* that contains RTF1, a dissociable PAF subunit critic

89 ditions [median 50% effective concentration (EC(50)) = 3.80 nM to 1.73 muM; selective index SI for 3-

90 When compared at six sites with concurrent EC and sap flow measurements, all three EC-based T estim

91 soil layer, and the electrical conductivity (EC) and nitrate content gradually decreased with increas

92 The presence of epicardial connections (ECs) between pulmonary veins (PVs) and other anatomic st

93 th marked target fields from 151 consecutive EC patients treated with carboplatin/paclitaxel and 41.4

94 ling methods used for emerging contaminants (ECs) in aquatic systems.

95 and HFpEF to compare excitation-contraction (EC) coupling and protein expression in these two forms o

96 lcium regulation and excitation-contraction (EC) coupling.

97 EC rescued SOCE to the level seen in control EC in a STIM1-dependent manner.

98 Elite controllers (EC) represent a small subset of HIV-1-infected people th

99 9 adult PWH, including 30 elite controllers (ECs), and 30 human immunodeficiency virus (HIV)-uninfect

100 . APOE3 expression in the entorhinal cortex (EC) and primary visual cortex (PVC) of aged APOE mice.

101 ysis, leaf gas exchange and eddy covariance (EC) fluxes.

102 able and area under the curve, and decreased EC(50); 2) a uniform dose-response profile across geneti

103 AMP-activated protein kinase), and decreases EC proliferation without affecting migration.

104 Inhibition of GLUT1 decreases EC glucose uptake and glycolysis, leading to energy depl

105 While HFrEF is characterized by defective EC coupling at baseline, HFpEF exhibits enhanced couplin

106 ed and subjected mice with EC-AGO1 deletion (EC-AGO1-knockout [KO]) and their wild-type littermates t

107 Although large EC entropy changes, DeltaS(EC) , and temperature changes, DeltaT(EC) , have been ac

108 ic fields and thus their EC strengths DeltaS(EC) /DeltaE and DeltaT(EC) /DeltaE are too low for pract

109 r EC strengths DeltaS(EC) /DeltaE and DeltaT(EC) /DeltaE are too low for practical applications.

110 DeltaS(EC) , and temperature changes, DeltaT(EC) , have been achieved in traditional thin-film cerami

111 endothelial permeability in MYLK-L-depleted EC and Mylk-L(-/-) lungs, thus demonstrating the novel r

112 k between diabetic and healthy donor-derived ECs corroborate the H + T-induced RNA-chromatin interact

113 ntailing dynamic contribution of SHF-derived ECs to pharyngeal arches, the remodeling of endothelial

114 Studies determining EC(50) are limited by single time-point determinations o

115 logical processes linked to AFC in different EC levels and metabolic processes that support complex i

116 grates these opposing signals in directional EC migration.

117 ility of materials with high electrocaloric (EC) strengths is critical to enabling EC refrigeration i

118 Specially, potential electrochemical (EC) biosensor, surface enhanced Raman scattering (SERS)-

119 multaneously interrogated electrochemically (EC).

120 loric (EC) strengths is critical to enabling EC refrigeration in practical applications.

121 ulations all indicate that the much enhanced EC performances can be attributed to the all-scale hiera

122 For all donor tissues, the enriched EC cells improved the signal-to-background ratio and rel

123 The resulting clonally enriched ECs behaved like ECs, as measured by in vitro and in viv

124 Enterochromaffin (EC) cells are a subtype of EE cells that produce seroton

125 ccuracy and memory use for CAZyme and enzyme EC classification and annotation; (ii) the k-mer-based t

126 state-of-the-art tools on CAZyme and enzyme EC datasets found that: (i) eCAMI has the best performan

127 ased tools and deep-learning tools in enzyme EC prediction.

128 me commission) numbers and applied to enzyme EC prediction.

129 Whereas epicatechin (EC) and epigallocatechin (EGC) exhibited slow binding ki

130 ing, desensitizing current with an estimated EC(50)-value of pH 6.7 and a slow-developing, non-desens

131 We define exceptional EC (EEC) as HIV-1 subjects who maintain the EC character

132 man fibroblasts that were induced to express EC markers in Matrigel plug assay.

133 Our results represent the first extensive EC data-based estimates of ecosystem T permitting a data

134 We also describe assays for EC clonal and network formation, as well as transcriptom

135 , we demonstrate that CEPT1 is essential for EC function and tissue recovery after ischemia and that

136 rate accuracy in identifying MMR-D and TMB-H ECs directly from CE-CT.

137 evant, multivariate activity patterns in HC, EC, and vmPFC/mOFC were linearly related to the Euclidea

138 t developed a CD-AOF medium for hepatocytes, ECs, and stage-matched MCs, i.e., septum transversum mes

139 is proposed and demonstrated to achieve high EC strength in poly(vinylidene fluoride-trifluoroethylen

140 te materials with potentially extremely high EC performance.

141 lidated markers to HIO ECs, we find that HIO ECs grown in vitro share the highest similarity with nat

142 gene signatures and validated markers to HIO ECs, we find that HIO ECs grown in vitro share the highe

143 opathy in the entorhinal cortex-hippocampal (EC-HIPP) network, we demonstrate that hAPP overexpressio

144 ion is regulated by Notch signaling in human ECs, and its function is required for the hypersprouting

145 a-B (NF-kappaB)-associated elements in human ECs.

146 he early transcriptional programs of hypoxic ECs by using RNA-Seq of primary cultured human umbilical

147 nd that both behavior and neural activity in EC and vmPFC/mOFC reflected the Euclidean distance to th

148 However, the roles of EMPs induced by CS in EC homeostasis are still unclear.

149 These differences in EC coupling and beta-adrenergic sensitivity may help exp

150 lated BMP6 expression in ECs was involved in EC migration.

151 esence of significantly light Si isotopes in EC-metals (delta(30)Si >= -6.94 +/- 0.09 per mille, Mg/S

152 n were detected by fluorescent microscopy in EC cytoplasm (associated with endoplasmic reticulum and

153 erable pathologic complete response (pCR) in EC.

154 circuit through HIF-1alpha and RBPJkappa in EC sprouting angiogenesis.

155 s induced thicker capillary-like branches in ECs and increased collagen IV and laminin expression.

156 RhoJ deficiency in ECs efficiently suppressed aberrant angiogenesis in isch

157 Moreover, Fn14 deficiency in ECs maintained in vitro impermeability when stimulated b

158 t present with an acquired sex difference in ECs are more likely to be targets of sex steroids.

159 al dysfunction via mitochondrial dynamics in ECs.

160 STAT6 as well as cytokine gene expression in ECs challenged with IL-4/IL-13 and house dust mite (HDM)

161 vealed that YY1-regulated BMP6 expression in ECs was involved in EC migration.

162 those patients increased Fn14 expression in ECs.

163 gene fibulin-5, which when overexpressed in ECs ameliorates OFT morphology and function.

164 ent to induce a proinflammatory phenotype in ECs compared with MPs collected before therapy.

165 , Sugisawa et al. demonstrate that Piezo1 in ECs senses single-strand RNA (ssRNA) from intestinal mic

166 nd caveolae numbers were markedly reduced in ECs from EphB1-deficient (EphB1(-/-)) mice.

167 caused by reduced beta-catenin signaling in ECs, despite the close resemblance of the Kif11 CKO phen

168 ux in CMs and inhibition of tubulogenesis in ECs.

169 ic mice and QKI-7 is knocked-down in vivo in ECs, reperfusion and blood flow recovery are markedly pr

170 n of the OFT: alk5-/- OFTs exhibit increased EC numbers as well as extracellular matrix (ECM) and SMC

171 lar endothelial growth factor (VEGF)-induced EC migration was diminished in YY1-depleted human umbili

172 Here, we generated inducible, EC-specific Pkd2 knockout mice to examine vascular funct

173 he highest similarity with native intestinal ECs relative to kidney and lung.

174 Surprisingly, the introduced EC-GC10 encapsulated perovskite interfacial layer at the

175 ghest anion-transport activities for iodide (EC(50) =0.042 mum or 0.028 mol % relative to lipid), whc

176 0) = 3940 mg/L), higher than that of 2-IPMA (EC(50) > 4800 mg/L).

177 ted these iPSCs into endothelial cells (iPSC-ECs).

178 well as transcriptomic analysis of isolated ECs.

179 void of catalytic activity) into Mylk-L(-/-) EC rescued SOCE to the level seen in control EC in a STI

180 report the synthesis of two new spin labels, EC and ECm, both of which possess the rigidity and the r

181 Although large EC entropy changes, DeltaS(EC) , and temperature changes

182 tion is developed, and extraordinarily large EC strengths of a metal-free perovskite ferroelectric [M

183 resulting clonally enriched ECs behaved like ECs, as measured by in vitro and in vivo angiogenesis as

184 Cept1Lp/LpCre (+) ECs demonstrated decreased proliferation, migration, and

185 logy are imprecise clinical correlates of LS-EC.

186 d deviant angiogenic signaling in mouse lung EC and human fetal HPMEC.

187 In conclusion, CatA-mediated EC-SOD reduction in the heart contributes to increased o

188 TG7 silencing also reduced thrombin-mediated EC permeability by inhibiting the disassembly of VE-cadh

189 al factor for bovine and human microvascular EC, with an additivity with VEGF.

190 ndMT occurs in mouse pulmonary microvascular ECs in vivo under hyperglycemic conditions.

191 p53abn EC, 98% for POLEmut EC, 72% for MMRd EC, and 74% for NSMP EC (P < .001).

192 = .637); 68% versus 76% (P = .428) for MMRd EC; and 80% versus 68% (P = .243) for NSMP EC.

193 for their suitability to screen and monitor ECs at the catchment scale in the River Thames system (U

194 Mechanistically, in vivo in BMP9/10ib mouse ECs, sirolimus and nintedanib blocked the overactivation

195 chrome c oxidase (COX) specifically in mouse ECs, providing a model for vasculature-restricted respir

196 A sequencing data from tissue-specific mouse ECs generated by the Tabula Muris consortium.

197 d that the effects of AT and PM FTP, but not EC, were driven by Abeta+ individuals.

198 Here we demonstrate that AMs, but not ECs, constitutively secrete paracrine activity localized

199 velopment of better BRB/BBB models and novel EC barrier-inducing therapeutics.

200 OLEmut EC, 72% for MMRd EC, and 74% for NSMP EC (P < .001).

201 d EC; and 80% versus 68% (P = .243) for NSMP EC.

202 To investigate the transcriptomic basis of EC specificity, we analyzed single-cell RNA sequencing d

203 hAPP/Abeta, but not tau, in the emergence of EC neuronal hyperactivity and impaired theta rhythmicity

204 differences were observed between groups of EC and NS (myeloperoxidase [MPO], matrix metalloproteina

205 als (CIs) associated with various metrics of EC exposure.

206 derlying the observed metabolic phenotype of EC-AGO1-KO.

207 ELR associated with 45 years of EC exposure at 50, 20, and 1 mug/m(3) were 3.0%, 0.99%,

208 significantly associated with the absence of ECs (29.6% in patients without ECs versus 16.2% in patie

209 to EVs which inhibits influenza infection of ECs in vitro and in vivo.

210 promoting the proliferation and migration of ECs that are critical in the pathogenesis of transplant

211 by triggering a proinflammatory phenotype of ECs.

212 d and maintain this endogenous population of ECs within HIOs (vHIOs).

213 are strongly associated with the presence of ECs.

214 mp2b-induced ectopic angiogenic sprouting of ECs in the developing embryo and provide pharmacological

215 monitor the MSCs and tunneling structure of ECs.

216 and locally required to specify a subset of ECs.

217 protocol for isolation of different types of ECs and CD157(+) vascular-resident endothelial stem cell

218 ations and conversion to FCs, while opposing EC production.

219 ts can affect calculated Michaelis-Menten or EC(50)/IC(50) kinetic parameters.

220 r allograft models, we show that systemic or EC specific suppression of phosphoinositide recycling re

221 angiogenic sprouting of Slug overexpressing EC.

222 he 5-year RFS with CTRT versus RT for p53abn EC was 59% versus 36% (P = .019); 100% versus 97% for pa

223 ve-year RFS was 48% for patients with p53abn EC, 98% for POLEmut EC, 72% for MMRd EC, and 74% for NSM

224 Pcs (EC(50) ~ 3-50 nM) than for anionic Pcs (EC(50) ~ 0.3-10 muM), the latter being additionally sign

225 irmed higher photoactivity for cationic Pcs (EC(50) ~ 3-50 nM) than for anionic Pcs (EC(50) ~ 0.3-10

226 anisms, leading to breakdown of the pericyte-EC interaction.

227 henylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28) catalyzes the final step in the biosynthesi

228 for patients with p53abn EC, 98% for POLEmut EC, 72% for MMRd EC, and 74% for NSMP EC (P < .001).

229 ); 100% versus 97% for patients with POLEmut EC (P = .637); 68% versus 76% (P = .428) for MMRd EC; an

230 The principal finding is that postnatal EC-specific loss of Kif11 leads to severely stunted grow

231 The protocol enables isolation of primary ECs and VESCs that can be used for a wide range of downs

232 ence of a population of highly proliferative ECs that likely arise from multiple miEC populations and

233 ibition of protein glycosylation can promote EC proliferation and angiogenesis and may represent a th

234 complex restrains PHD-2 activity, promoting EC survival in a HIF-dependent manner, and furthermore d

235 Protecting ECs from apoptosis in this model did not prevent capilla

236 dephosphorylates p38, altogether protecting ECs against cell stress occurring, for example, during t

237 ncentrations.Methods: We used a quantitative EC job-exposure matrix for exposure assessment.

238 tive agonist activity in the moderate range (EC(50) = 1-100 nM) were subjected to (18)F-fluorination,

239 y at MT receptors, with compound 21 reaching EC(50) of 0.36 nM.

240 order of 160-fold higher than the recognised EC(50) toxic levels of copper in soils.

241 man emphysema lung samples exhibited reduced EC HIF-2alpha expression.Conclusions: Here, we demonstra

242 the LV of transgenic mice (CatA-TG) reduced EC-SOD protein levels by 43%.

243 are permitted as food additives (Regulation EC No 1129/2011) but their undeclared utilisation is con

244 an or equal to those found in the respective EC tissues, providing a possible explanation for TZ tiss

245 ostnatal retinal endothelium reduces retinal EC proliferation and lowers vascular outgrowth, without

246 ion has strong prognostic value in high-risk EC, with significantly improved RFS with adjuvant CTRT f

247 resent study was to measure the sensitivity (EC(50)-values) of 10 aquatic invertebrates toward a 24 h

248 nd human endothelial cells in vitro, we show ECs deficient in CDP-diacylglycerol synthase 2 are uniqu

249 h 2 clusters (C5 and C8) also expressed some EC genes.

250 ional networks that maintain tissue-specific EC identity and to identify novel angiocrine and functio

251 iocrine interactions between tissue-specific ECs and other cell types by analyzing ligand and recepto

252 rithm, we found that certain tissue-specific ECs cluster strongly by tissue (eg, liver, brain), where

253 tional relationships between tissue-specific ECs.

254 CLDN5), a junctional protein that stabilizes ECs, and are important for proper neuronal function.

255 enzyme thiocyanate dehydrogenase (suggested EC 1.8.2.7) that was purified from the haloalkaliphilic

256 tome, the pathways and networks that sustain EC heterogeneity have not been fully delineated.

257 Cancer cells rely on the enzyme telomerase (EC 2.7.7.49) to promote cellular immortality.

258 LCA is also a highly potent ligand for TGR5 (EC(50) 0.52 mum).

259 higher correlation to sap flow-based T than EC-based ET.

260 eases claudin-5 abundance, and we found that EC-selective miR-15a/16-1 deletion enhanced claudin-5 mR

261 vivo matrigel plug assay, we then found that EC-specific YY1 ablation inhibited growth factor-induced

262 all the Swiss-Prot enzymes classified by the EC (enzyme commission) numbers and applied to enzyme EC

263 , and sensitivity of 4.9 mA/mM((DA)), in the EC.

264 EC (EEC) as HIV-1 subjects who maintain the EC characteristics without disease progression for more

265 uring differentiation of the monolayers, the EC cell lineage was significantly altered by both the cu

266 review, we highlight the significance of the EC as a major player in memory processing, along with ot

267 The transplantation of the EC clones caused arterio-occlusive PH in rats exposed to

268 ections, of which the lateral regions of the EC display denser AChE staining than that of the medial

269 l and myeloarchitectural organization of the EC in the common marmoset Callithrix jacchus.

270 nity and inflammatory disorders hinge on the EC-neutrophil interaction.

271 membrane protein of the SR unrelated to the EC coupling process.

272 of very high electric fields and thus their EC strengths DeltaS(EC) /DeltaE and DeltaT(EC) /DeltaE a

273 These EC clones engrafted in the pulmonary arteries.

274 rent EC and sap flow measurements, all three EC-based T estimates show higher correlation to sap flow

275 e loading factor Nipped-B triggers an ISC to EC differentiation program that is independent of Notch

276 an over 2-fold increase in CTC attachment to ECs or Balb/C mouse lungs, respectively, compared to unt

277 Taken together, EC PI3Kbeta inactivation with sunitinib inhibition reduc

278 TRPV4(EC) channels co-localize with IK/SK channels in mesenter

279 mity necessary for their activation by TRPV4(EC) channels in PAs.

280 tion of signalling elements determines TRPV4(EC) -IK/SK vs. TRPV4(EC) -eNOS coupling in resistance ar

281 pulmonary arteries, which may explain TRPV4(EC) -IK/SK channel coupling in mesenteric arteries and i

282 hin nanometer proximity to eNOS limits TRPV4(EC) -eNOS signalling in MAs.

283 ements determines TRPV4(EC) -IK/SK vs. TRPV4(EC) -eNOS coupling in resistance arteries.

284 IK/SK channels co-localized with TRPV4(EC) channels at myoendothelial projections (MEPs) in MAs

285 and thus outperforms previous research type EC-QCL setups as well as commercially available instrume

286 In unstimulated ECs, YAP localized mainly in the cytoplasm.

287 inflammatory mediators between e-cig users (EC) and these other groups were also assessed.

288 ngiogenesis patterns of Human Umbilical Vein EC (HUVEC).

289 Seq of primary cultured human umbilical vein ECs exposed to progressively increasing severity and dur

290 reening to identify compounds 29 and 30 with EC(50) values of 110 and 120 nM, respectively, and witho

291 Of these, 57, with EC(50) = 145 nM and a solubility of 33 muM, showed high

292 In contrast, 63, with EC(50) = 162 nM and a solubility of 9 muM, showed lower

293 lar acetylation and had strong activity with EC(50) of 1-3 muM against proliferation of several tumor

294 Ultimately, we identified 399 compounds with EC(50) <= 5 uM with no effect in counterscreen assays.

295 Women diagnosed with EC or atypical hyperplasia (AH) were offered LS testing.

296 We generated and subjected mice with EC-AGO1 deletion (EC-AGO1-knockout [KO]) and their wild-

297 ability to induce EndMT in co-cultures with ECs.

298 ave considerable transcriptomic overlap with ECs from other tissues.

299 ts without ECs versus 16.2% in patients with ECs; P=0.014).

300 he absence of ECs (29.6% in patients without ECs versus 16.2% in patients with ECs; P=0.014).