ライフサイエンスコーパス: FAE

1 FAE cells also produce chemokines that attract Ag-presen

2 FAE decreased 5-HTT binding sites in the medial nucleus

3 FAE decreased 5-HTT binding sites temporarily in the ven

4 FAE increased 5-HTT binding sites in cortical layers 5,

5 FAE led to distinct effects on 5-HTT sites depending on

6 FAE(XynZ) had similar properties.

7 FAE, all the tested flavonoids except genistein, and two

8 FAE-CBD(XynZ) had a molecular mass of 45 kDa that corres

9 FAEs and ECs are synthesized by a series of endogenous e

10 FAEs are hydrolyzed intracellularly by either fatty acid

11 ranged between 3.9-7.6mug/g and 1299-1607mug FAE/g and was higher for high altitude cultivars.

12 nant feruloyl esterase domain of XynZ alone (FAE(XynZ)) and with the adjacent cellulose binding domai

13 These results show that an FAE M-cell targeting protein Ag delivery system facilita

14 -bound immunoglobulin M restored B cells and FAE development.

15 striatum cause a local increase in NAPE and FAE levels, which precedes neuronal cell death.

16 ed expression programs in both follicles and FAEs, with a decrease in enterocyte antimicrobial and ab

17 expression map of the ILF and its associated FAE in the mouse small intestine.

18 We show that TLR2 is expressed in both FAE and villus epithelium, but TLR2 activation by peptid

19 lly linked to behavioral deficits induced by FAE remain poorly understood.

20 ed contextual fear memory deficit induced by FAE, and reversed the hippocampal expression changes in

21 In contrast, FAE increased 5-HTT sites in the lateral nucleus of the

22 vide new MS-based methodologies for in-depth FAE and bsAb formation monitoring.

23 with the adjacent cellulose binding domain (FAE-CBD(XynZ)) were characterized.

24 rphic heavily exposed fetal alcohol effects (FAE; diagnosed prior to MRI1), and 22 individuals with F

25 type II fatty acid synthesis and elongation (FAE), tricarboxylic acid, amino sugar, heme, lipoate, an

26 Flexible airway endoscopy (FAE) is an accepted and frequently performed procedure i

27 These innate responses to flagellin enhance FAE functions and may promote adaptive immune responses

28 vidence that formaldehyde-activating enzyme (FAE) homologs might be involved in methylotrophy.

29 's patch (PP) follicle-associated epithelia (FAE) to limit entry points for STm invasion.

30 a subset of follicle-associated epithelial (FAE) cells, known as M cells, conduct the transcytosis o

31 ria/mm(2) of follicle-associated epithelial (FAE) surface were found in three-dimensional reconstruct

32 esent in the follicle-associated epithelium (FAE) above organized conjunctiva-associated lymphoid tis

33 to label the follicle-associated epithelium (FAE) almost exclusively.

34 ncluding the follicle-associated epithelium (FAE) and microfold (M) cells of Peyer's patches, but als

35 asion of the follicle associated epithelium (FAE) by an enteric pathogen and were responsible for the

36 Fs and their follicle-associated epithelium (FAE) impeded the characterization of their spatial gene

37 Follicle-associated epithelium (FAE) in the intestinal Peyer's patches contains M cells

38 Instead, follicle-associated epithelium (FAE) M cell differentiation was required and sufficient

39 estricted to follicle-associated epithelium (FAE) of ileal Peyer's patches.

40 through the follicle-associated epithelium (FAE) of Peyer's patch (PP) is the critical first step in

41 s across the follicle-associated epithelium (FAE) of Peyer's patches.

42 pecialized follicular-associated epithelium (FAE) overlying mucosa-associated lymphoid tissues, their

43 The follicle-associated epithelium (FAE) plays key roles in antigen uptake and subsequent in

44 cells in the follicle-associated epithelium (FAE) region of Peyer's patches.

45 The follicle-associated epithelium (FAE) secretes chemokines important in the recruitment of

46 covered by a follicle-associated epithelium (FAE) specialized for the uptake of antigens.

47 specialized follicle-associated epithelium (FAE) that contains M cells, which mediate uptake and tra

48 gions of the follicle-associated epithelium (FAE), although the conditions responsible for expression

49 s lining the follicle-associated epithelium (FAE).

50 (BG-12, Tecfidera) is a fumaric acid ester (FAE) that was advanced as a multiple sclerosis (MS) ther

51 s to probe the active site of two esterases (FAE-III and CinnAE) from Aspergillus niger.

52 other unsaturated fatty acid ethanolamides (FAEs) (e.g. linoleoylethanolamide) without affecting tho

53 Fatty acid ethanolamides (FAEs) and endocannabinoids (ECs) have been shown to alle

54 The fatty acid ethanolamides (FAEs) are a family of bioactive lipid mediators that inc

55 nd monounsaturated fatty acid ethanolamides (FAEs), a family of endogenous lipid agonists of peroxiso

56 PEs into bioactive fatty-acid ethanolamides (FAEs).

57 Amides of fatty acids with ethanolamine (FAE) are biologically active lipids that participate in

58 Fatal adverse events (FAEs) have been reported in cancer patients treated with

59 determine the risk of fatal adverse events (FAEs) in patients with cancer treated with VEGFR TKIs.

60 adverse events (SAEs), fatal adverse events (FAEs), and all-cause mortality.

61 suprachoroidal space and fluid-air exchange (FAE) was started with sequential increases in infusion a

62 gG4 undergoes a process of Fab-arm exchange (FAE) in which the heavy chains of antibodies of differen

63 undergo a process known as Fab arm exchange (FAE).

64 ittle is known about fetal alcohol exposure (FAE) effects on adult infections.

65 Fetal alcohol exposure (FAE) is the leading preventable developmental cause of c

66 mined the effects of fetal alcohol exposure (FAE) on serotonin transporter (5-HTT) binding sites in t

67 FASD), the result of fetal alcohol exposure (FAE), affects 2-11% of children worldwide, with no effec

68 f diseases caused by fetal alcohol exposure (FAE).

69 The autocrine activation of RelB-expressing FAE enterocytes by RANKL/RANK induces the EMT-regulating

70 in Luria-Bertani (LB) broth induce extensive FAE loss and exhibit efficient M-cell invasion, whereas

71 erty of a flavonoid-rich apple peel extract (FAE), its constituents, selected flavonoids and some que

72 ollowing: a 3-methoxy group is essential for FAE-III activity, whereas a 3-methoxy group precluded ac

73 elate to k(cat) for CinnAE (r = 0.33) or for FAE-III (r = 0.43).

74 Differences in Km values for FAE-III were small (0.45-2.08 mM) but there were two ord

75 R for SAEs was 1.86 (95% CI, 1.63-2.11), for FAEs was 3.30 (95% CI, 1.56-7.00), and for death was 1.3

76 t conversely, were only able to bind to free FAE-III.

77 Using a human FAE model, we show that the tyrosine kinase HCK regulate

78 nitive function that may contribute to human FAE, and identify potential mechanisms for future therap

79 IgG4 FAE is suggested to be an important biological mechanism

80 ditions, the S228P mutation can prevent IgG4 FAE to undetectable levels both in vitro and in vivo.

81 ing the pocket were found to be conserved in FAE A from Orpinomyces sp., which further supports the p

82 expression in rhesus macaques was reduced in FAE and, significantly, absent in germinal centers.

83 t1 inhibitor to control neonates resulted in FAE-like deficits in fear memory and hippocampal allele-

84 t invasion of cultured cells, fail to induce FAE destruction and, when inoculated in LB, are attenuat

85 ity and the adult immune system, we infected FAE adult mice with influenza virus.

86 ot entirely understood and studies measuring FAE in ex vivo matrices have been hampered by the presen

87 eatment was higher in phenolic acid (7.36 mg FAE/g), flavonoid (206.74 mug catechin/g), anthocyanin (

88 In the HUVEC model, FAE, quercetin-3-O-glucoside and quercetin-3-O-glucuroni

89 FAE, suggesting that other TLRs may modulate FAE functions.

90 On the other hand, the monounsaturated FAE oleoylethanolamide (OEA) reduces feeding and body we

91 3] cc at MRI1 and 1465.4 [129.4] cc at MRI2; FAE, 1375.6 [134.1] cc at MRI1 and 1371.7 [120.3] cc at

92 NAPE, but not FAE, accumulation is enhanced in mice lacking NAPE-PLD,

93 of bacteria increased to 579 +/- 44/mm(2) of FAE surface and they had moved 50% deeper into the folli

94 erminal amino acids, residues 247 to 286, of FAE(XynZ) resulted in protein without activity.

95 hoxy substitutions increased the activity of FAE-III, and decreased the activity of CinnAE; (c) 4-hyd

96 Here, we first review the effects of FAE on corticostriatal development and its impact on bot

97 efore, to determine the long-term effects of FAE on disease susceptibility and the adult immune syste

98 n epithelial-mesenchymal transition (EMT) of FAE enterocytes into M cells.

99 We have also demonstrated that the extent of FAE destruction correlates with the extent of M-cell inv

100 ittee members highlighting the importance of FAE-specific airway management techniques and anesthesia

101 To date, the mechanism of FAE is not entirely understood and studies measuring FAE

102 for the first time for online monitoring of FAE and bsAb formation using Hz6F4-2v3 and natalizumab,

103 Null mutants of FAE and homologs revealed that FAE and FAE2 influence th

104 Together, our results highlight the role of FAE M cell differentiation and MNP maturation in postnat

105 he activity of CinnAE, but decreased that of FAE-III; (d) the rate of hydrolysis with sodium hydroxid

106 The most common causes of FAEs were hemorrhage (23.5%), neutropenia (12.2%), and g

107 ast decades, increasing the concentration of FAEs and ECs through the inhibition of degrading enzymes

108 The incidence of FAEs related to VEGFR TKIs was 1.5% (95% CI, 0.8% to 2.4

109 The overall incidence of FAEs with bevacizumab was 2.5% (95% CI, 1.7%-3.9%).

110 group analysis, no difference in the rate of FAEs was found between different VEGFR TKIs or tumor typ

111 KIs was associated with an increased risk of FAEs compared with control patients.

112 mab was associated with an increased risk of FAEs in patients receiving taxanes or platinum agents (R

113 ut was not associated with increased risk of FAEs when used in conjunction with other agents (RR, 0.8

114 mab was associated with an increased risk of FAEs, with an RR of 1.46 (95% CI, 1.09-1.94; P = .01; in

115 Overall, FAE and most of the flavonoids tested showed ACE inhibit

116 d-type S. typhimurium on mouse Peyer's patch FAE is dependent on the inoculum composition.

117 Development of Peyer's patches, FAE, and M cells was found to be impaired in mice that h

118 of randomized controlled trials in pediatric FAE.

119 lished technical standards on how to perform FAE in children are lacking.

120 delineate technical standards for performing FAE in children.

121 Electrical recordings revealed polarized FAE with sustained outward current and small transepithe

122 The polyunsaturated FAE anandamide (arachidonoylethanolamide) increases food

123 atal administration of T4 and metformin post FAE affect memory via elevating Dnmt1 and consequently n

124 xine (T4) or metformin to neonatal rats post FAE and rats were tested in the hippocampus-dependent co

125 a gut microbe residing on ileum villi and PP FAE that mediates resistance to STm infection.

126 enyl-4-carboxamide (3) inhibit NAAA, prevent FAE hydrolysis in activated inflammatory cells, and redu

127 ll allow researchers to monitor and quantify FAE of their own IgG4 molecules in physiologically relev

128 evant matrices for assessing and quantifying FAE.

129 A novel method for quantifying FAE using a single MSD immunoassay is also reported and

130 unity, but their possible role in regulating FAE functions is unknown.

131 t male hippocampus, while metformin restored FAE-caused changes in Igf2 expression only.

132 eta-analysis show that serious risks of SAE, FAE, and death with idelalisib treatment were evident by

133 lamide) without affecting those of saturated FAEs (e.g. palmitoylethanolamide).

134 e-buffered saline fail to induce significant FAE disruption and invade M cells at significantly lower

135 min-gamma-positive O55:H7 EPEC also targeted FAE.

136 bility to influenza virus infection and that FAE individuals could be at increased risk for severe an

137 Moreover, we demonstrate that FAE mice have impaired adaptive immune responses, includ

138 ll mutants of FAE and homologs revealed that FAE and FAE2 influence the growth rate and FAE3 influenc

139 Together, our results suggest that FAE induces significant and long-term defects in immunit

140 al neuroprotection as it was recognized that FAEs are capable of activating the antioxidative transcr

141 The FAE and FAS groups exhibited enduring stepped volume def

142 The FAE can transcytose a variety of luminal contents, inclu

143 FTR) generated the ionic currents around the FAE.

144 ntified Lepr+ subepithelial telocytes at the FAE top, which are distinct from villus tip Lgr5+ telocy

145 d, also enhanced microparticle uptake by the FAE and induced DC migration into the FAE, suggesting th

146 nstrated that CCL9 mRNA was expressed by the FAE but not by the villus epithelium.

147 pithelial transport of microparticles by the FAE of mouse Peyer's patches in vivo.

148 By morphological criteria, the FAE contains >90% M cells.

149 espite these persistent volume deficits, the FAE participants and FAS participants showed patterns of

150 vivo porcine model confirms that during the FAE in PPV, pressurized air from an infusion cannula mal

151 her chemokine specifically secreted from the FAE of mouse Peyer's patches, CCL9 (MIP-1gamma, CCF18, M

152 w that, like mammalian M cells, those in the FAE of the chicken bursa also express SOX8, MARCKSL1, TN

153 We previously revealed that M cells in the FAE of the chicken lung, bursa of Fabricius (bursa), and

154 e resulted in receptor redistribution in the FAE only.

155 subepithelial dendritic cells (DCs) into the FAE, better positioning DCs for antigen capture.

156 dent migration of subepithelial DCs into the FAE, but not into villus epithelium of wild-type and TLR

157 by the FAE and induced DC migration into the FAE, suggesting that other TLRs may modulate FAE functio

158 ed dramatic morphological alterations of the FAE in rabbit PP.

159 Further confocal microscopy analysis of the FAE surface showed that a significant increase in the nu

160 his problem by evaluating the ability of the FAE to bind, internalize, and transport fluorescent poly

161 ls regulate the gatekeeping functions of the FAE to promote Ag capture by DCs in organized mucosal ly

162 were accompanied by enhanced ability of the FAE to transport antigens.

163 atal dysfunctions to account for some of the FAE-induced cognitive deficits.

164 the protein level, CCL9 was detected on the FAE and on extracellular matrix structures within the do

165 lectin was found to specifically target the FAE, while the control lectin did not.

166 a provide the first direct evidence that the FAE-specific antigen sampling function may be manipulate

167 Thus, the FAE of Peyer's patches responds to TLR2 ligands in a man

168 Typhimurium (S. Typhimurium) localize to the FAE independently of chemotaxis in an ex vivo mouse caec

169 How Salmonella localize to the FAE is not well characterized.

170 l potentials attracted S. Typhimurium to the FAE while Escherichia coli (E. coli) localized to the vi

171 endent on the expression of CD155 within the FAE, including the M cells, and on cells within Peyer's

172 inhibition of CFTR decreased S. Typhimurium FAE localization but increased E. coli recruitment.

173 cies, and special procedures associated with FAE in children.

174 ts were greater than among participants with FAE, which were greater than volumes among participants