ライフサイエンスコーパス: FDP

1 FDP + CsA prolongs cardiac survival and FDP inhibits T-c

2 FDP completely inhibited interleukin-2 expression at 5,0

3 FDP did not stimulate transcription inhibition by CcpA n

4 FDP induction of PAI-1 suggests a matrix-cell feedback p

5 FDP is also helpful for inflammatory lesions in BP patie

6 FDP is made using bis-1,5(tributyl ammonium) pentamethyl

7 FDP maximally inhibits T-cell proliferation and concomit

8 FDPs are more potent than fibrinogen, inducing a concent

9 FDPs contain a dinuclear iron active site similar to tha

10 FDPs contain a distinctive non-heme diiron/flavin mononu

11 FDPs serve as the terminal components for reductive scav

12 59 7492 ug/L vs. 1738 1478 ug/L; P < 0.0001; FDP: 11.20 5.88 mg/L vs. 5.13 3.44 mg/L; P = 0.0003), wh

13 hil counts [D-dimer: r = 0.3625, P = 0.0013; FDP: r = 0.2880, P = 0.0472]) in BP patients.

14 centration [D-dimer: r = 0.3928, P = 0.0058; FDP: r = 0.4379, P = 0.0019] and eosinophil counts [D-di

15 s with enantiomerically pure [1-(2)H(1)](1R)-FDP revealed that the putative bisabolyl-derived 1,6-pat

16 Levels of PTF1+2, FDP, and D-dimer decreased as symptoms improved.

17 nt species from a wide phylogenetic range (3 FDPs in tropics, 5 in subtropics and 5 in temperate zone

18 4, FDP 350 mg/kg perioperatively 13.5+/-1.4, FDP 350 mg/kg twice daily 11.4+/-0.75, CsA 2.5 mg/kg dai

19 n survival in days were: saline 7.12+/-0.64, FDP 350 mg/kg perioperatively 13.5+/-1.4, FDP 350 mg/kg

20 transferases, farnesyl diphosphates, (2E,6E)-FDP and (2Z,6Z)-FDP, were isolated in greater than 80 %

21 on incubation of MtTPS5 with natural (2E,6E)-FDP.

22 to study the promiscuity of MtTPS5, (2Z,6E)-FDP, an analogue of presumptive reaction intermediates f

23 from incubations of DCS with 6F-FPP, (2Z,6E)-FDP, neryl diphosphate, 6,7-dihydro-FDP, and NDP seem to

24 rticular, the strong inhibition of DCS by 6F-FDP, coupled to the exclusive bisabolyl- and terpinyl-de

25 rnesyl diphosphates, (2E,6E)-FDP and (2Z,6Z)-FDP, were isolated in greater than 80 % yields.

26 nit were as follows: SAP, 2.177; SWAP, 1.96; FDP, 1.277; and GRP, 1.04.

27 Fermented dairy product A (FDP-A), but neither the supernatant from FDP-A nor beta-

28 gly, the binding of the allosteric activator FDP does not directly influence the binding of the subst

29 Additionally, FDP-lysine smoothly transforms into another heterocycle,

30 A variety of factors can affect FDP conformity.

31 , We assessed the proposed algorithm against FDP-M-net and U-finger in SFinGe synthetic dataset, wher

32 -like and flavodoxin domains typical for all FDPs, an extra NAD(P)H:flavin oxidoreductase module and

33 Unlike a "stand-alone" FDP that lacks Rb and oxidoreductase domains, this natur

34 As an FDP synthase, PcIDS1 could be associated with the format

35 red ~1548 novel cross-linking partners of an FDP-modified protein.

36 HR: 1.61; HSP70 >0.625 ng/ml, HR; 2.26; and FDP >/=1.0 mug/ml, HR: 1.62 (p < 0.0001 for all).

37 The images of AP and FDP were independently interpreted by 2 radiologists wit

38 Plasma D-dimer and FDP are convenient markers to evaluate BP severity assis

39 stemic glucocorticoid treatment, D-dimer and FDP levels decreased post-therapy (D-dimer: 5559 7492 ug

40 The plasma D-dimer and FDP levels were higher in BP patients than in HZ control

41 DIC diagnostic test panel, with D-dimer and FDP providing a rapid and specific diagnosis, antithromb

42 The D-dimer and FDP tests offered the best test panel in the diagnosis o

43 ive PAI-1 is demonstrated in fibrinogen- and FDP-stimulated conditioned media.

44 ions was phenotypically evaluated for MD and FDP, and genotypically characterized using the genotypin

45 These results indicate that, in Hr(NO) and FDP(NO), the coordinated NO is exceptionally electron ri

46 allosteric communication between the PEP and FDP sites in an allosteric relay mechanism.

47 Thus, communication between the PEP and FDP sites occurs structurally through the metal by an al

48 that simultaneous binding of Mn2+, PEP, and FDP is considerably favored over the sum of their indepe

49 g insight to the severity and prognosis, and FDP (rapid and less expensive than D-dimer) to follow-up

50 tivity 100%, and specificity 67%; PT/PTT and FDP combination (n = 71), efficiency 86%, sensitivity 91

51 videnced by reduced contrast sensitivity and FDP performance, accompanied by alterations in inner and

52 l treatment effects by macular hole size and FDP duration.

53 FDP + CsA prolongs cardiac survival and FDP inhibits T-cell proliferation.

54 We aimed to evaluate the use of D-dimer and FDPs in assessing BP severity.

55 rmFDP, for easy use of the permutation-based FDP estimation method.

56 We also found an association between FDP and urticaria/erythema lesions (r = 0.3016, P = 0.03

57 iew did not demonstrate a difference between FDP and nFDP with respect to FTMH closure, although the

58 e test, the diagnostic effectiveness of both FDP and AP in breast cancer screening was calculated.

59 that are significantly associated with both FDP and MD.

60 This is followed by FDP (n = 71), efficiency 87%, sensitivity 100%, and spec

61 in protein-protein interactions mediated by FDP-modified proteins and uncovered ~1548 novel cross-li

62 Incubation of [(14)C]FDP with recombinant human squalene synthase led to [(14

63 ereas it yields only 18% C10 GDP but 82% C15 FDP in the presence of Mg(2+).

64 unit-cell crystalline domains, which we call FDP (few-unit-cell crystalline domain pentasil), is repo

65 binations, CcpA/NADP/HPr-P (Ser-46) and CcpA/FDP/HPr-P (Ser-46) synergistically stimulated DNA-bindin

66 ence (MD) regarding VA improvement comparing FDP and nFDP was MD -0.07 (95% CI: -0.12 to 0.01, P = 0.

67 ive risk (RR) of FTMH closure rate comparing FDP versus nFDP was RR 1.05 (95% confidence interval [CI

68 is of randomized controlled trials comparing FDP with no FDP (nFDP) across the MEDLINE, Embase, and C

69 Conversely, FDP-A prevented a decrease in Ruminococcus and increased

70 ggregate score based on serum levels of CRP, FDP, and HSP70 is a predictor of future risk of death an

71 Serum levels of CRP, FDP, and HSP70 were measured in 3,415 consecutive patien

72 Cyanobacterial FDPs constitute a specific protein group that evolved to

73 Evolution of unique cyanobacterial FDPs is discussed as a prerequisite for the development

74 ere as follows: SAP, 4.85 dB; SWAP, 9.03 dB; FDP, 4.29 dB; and GRP, 1.36 dB.

75 ative mechanisms, we examined a deflavinated FDP (deflavo-FDP) from Thermotoga maritima.

76 Both deflavo-FDP(NO) and the mononitrosyl adduct of the flavinated FP

77 stable diiron-mononitrosyl complex (deflavo-FDP(NO)) that can react further with NO to form N(2)O.

78 ric oxide up to one NO per diferrous deflavo-FDP results in formation of a diiron-mononitrosyl comple

79 Reactions of the reduced (diferrous) deflavo-FDP with nitric oxide were examined by UV-vis absorption

80 sms, we examined a deflavinated FDP (deflavo-FDP) from Thermotoga maritima.

81 n addition of NO to the mononitrosyl deflavo-FDP supports the hyponitrite mechanism, but the concomit

82 ble diiron-dinitrosyl complex in the deflavo-FDP is consistent with a super-reduction pathway in the

83 The deflavo-FDP retains an intact diiron site but does not exhibit m

84 Both NO-treated and as-isolated deflavo-FDPs regain full NOR and O(2)R activities upon simple ad

85 onyl, termed 3-formyl-3,4-dehydropiperidino (FDP), exclusively on lysine residues.

86 ulted in N-(3-formyl-3,4-dehydropiperidino) (FDP)-lysine adducts at positions 5 and 25 and led to a c

87 Recently, we showed that FMN-free diferrous FDP from Thermotoga maritima exposed to 1 equiv NO forms

88 (2Z,6E)-FDP, neryl diphosphate, 6,7-dihydro-FDP, and NDP seem to be in better agreement with the pot

89 We propose the use of D-dimer, FDP, and antithrombin as the DIC diagnostic test panel,

90 tive correlations were found between D-dimer/FDP levels and BP severity markers (i.e. anti-BP180 IgG

91 The synthesis of 14,15-dimethyl-FDP, 12-methyl-FDP, 12-hydroxy-FDP, homo-FDP, and 15-met

92 l sulfoxide (DMSO)-fructose 1,6-diphosphate (FDP) i.p. for seven days and retested on the water maze.

93 Fructose-1,6-diphosphate (FDP) reduces postischemic reperfusion injury and is used

94 imulated 2-fold by fructose-1,6-diphosphate (FDP), 1.5-fold by oxidized or reduced forms of NADP, and

95 osteric activator, fructose 1,6-diphosphate (FDP), does not directly communicate with the substrate,

96 metabolism [e.g., fructose 1,6-diphosphate (FDP), phosphoenolpyruvate (PEP), and citrate] and by the

97 E,E)-farnesyl and dimethylallyl diphosphate (FDP and DMADP) to generate the semiochemicals (E)-beta-f

98 (GGDPS) that condenses farnesyl diphosphate (FDP) and isopentenyl pyrophosphate.

99 (GDP) and only 4% C15-farnesyl diphosphate (FDP) in the presence of Co(2+) or Mn(2+) as a cofactor,

100 potency at inhibiting farnesyl diphosphate (FDP) synthase (their intracellular target), the N-BPs ar

101 t cyclization of (E,E)-farnesyl diphosphate (FDP) to the cadinane sesquiterpene delta-cadinene, the p

102 yzes the conversion of farnesyl diphosphate (FDP) to the plant sesquiterpene (+)-germacrene A.

103 olyisoprenyl phosphate farnesyl diphosphate (FDP), PSDP was not a substrate for type 2 lipid phosphat

104 oprenoid intermediate, farnesyl diphosphate (FDP), to sesquiterpene phytoalexins in cotton (Gossypium

105 ural substrate (2E,6E)-farnesyl diphosphate (FDP).

106 rom the reaction of fluorescein diphosphate (FDP) and immuno-complex conjugated with ALP.

107 f concentrations of fluorescein diphosphate (FDP), a fluorogenic alkaline phosphatase substrate, with

108 DMSO-FDP treatment was discontinued and rats were retested on

109 The results indicate that a DMSO-FDP combination improves VSM secondary to chronic brain

110 After DMSO-FDP, a 54% improvement in their VSM was seen which nearl

111 ssypium arboreum cyclizes (1RS)-[1-2H](E, E)-FDP to >98% [5-2H]and [11-2H]CDN.

112 proposed for the formation of CDN from (E,E)-FDP and for the formation of CDN, (E)-beta-farnesene, an

113 ues demonstrate that the synthase uses (E,E)-FDP as effectively as (3R)-nerolidyl diphosphate in the

114 genetic distance between the trees, but each FDP exhibits its own unique pattern of exceptions to thi

115 tion to October 3, 2021, for RCTs evaluating FDP versus non-FDP (nFDP).

116 The class F FDP found in H. meleagridis (HmFDPF) has domain organiza

117 ults on the same deflavinated and flavinated FDP, which detected N2O as a product.

118 ng, among others, deuterated and fluorinated FDPs.

119 er training, either for natural teeth or for FDP (all P >0.05).

120 MRI acquisition time for FDP was 17 minutes, versus 3 minutes for the AP.

121 There are four FDPs in Synechocystis sp. PCC 6803 (Flv1 to Flv4).

122 Synechocystis sp. PCC 6803 has four FDPs (Flv1-4), which are essential for the photoprotecti

123 e mononitrosyl adduct of the flavinated FPD (FDP(NO)) show nu(NO) at 1681 cm(-1), which is also unusu

124 Different from FDP homodimers in anaerobic microbes, Synechocystis Flv2

125 A (FDP-A), but neither the supernatant from FDP-A nor beta-irradiated (IR) FDP-A, caused a significa

126 n oxidoreductase module and thus differ from FDPs in other Bacteria and Archaea.

127 ination generally depend on scales in global FDPs.

128 ivity with a substrate preference for PSDP > FDP > phosphatidic acid.

129 rium-labeling experiments with [12,13-(2)H6]-FDP support a germacrene-humulene rearrangement linking

130 le experiment, but the probability of a high FDP is small when a high number and proportion of correc

131 s yielded five main themes that defined home FDP compliance were identified: posture discomfort, doct

132 hyl-FDP, 12-methyl-FDP, 12-hydroxy-FDP, homo-FDP, and 15-methyl-FDP was also achieved.

133 his bioactivity of FDP is conserved in human FDP, is not limited to trophoblast cells, and is associa

134 4,15-dimethyl-FDP, 12-methyl-FDP, 12-hydroxy-FDP, homo-FDP, and 15-methyl-FDP was also achieved.

135 results demonstrate that viable bacteria in FDP-A reduced CR-induced colonic crypt hyperplasia and p

136 tion of Jak2 and Stat5a and Stat5b occurs in FDP-C1 cells expressing either the entire GH receptor or

137 ron-mononitrosyl complex with NO, whereas in FDP(NO) the increased nucleophilicity of the nitrosyl gr

138 t of an unusually small FeNO angle, while in FDP(NO), the Fe(III)(NO(-)) structure may be due to a se

139 cterization of diiron redox intermediates in FDPs.

140 imed to identify the factors that influenced FDP compliance.

141 lation exists between potency for inhibiting FDP synthase and potency for inhibiting Dictyostelium di

142 d that, although high potency for inhibiting FDP synthase is favored when the nitrogen atom in a N-BP

143 ernatant from FDP-A nor beta-irradiated (IR) FDP-A, caused a significant reduction in colonic crypt h

144 rofiling the gut microbiota revealed that IR-FDP-A promoted higher levels of phylotypes belonging to

145 5.0 mg/kg daily 12.4+/-0.81, CsA 2.5 mg/kg + FDP 350 mg/kg twice daily 17.6+/-0.4, and CsA 5 mg/kg +

146 kg twice daily 17.6+/-0.4, and CsA 5 mg/kg + FDP 350 mg/kg twice daily 28.2+/-0.97.

147 imer: 3297 2517 ug/L vs. 569.70 412.40 ug/L; FDP: 9.74 5.88 mg/L vs. 2.02 1.69 mg/L, respectively, P

148 No correction method can guarantee a low FDP in a single experiment, but the probability of a hig

149 We conclude that the macaque FDP consists of four neuromuscular compartments, each of

150 067 bp; we referred to this region as the MD/FDP locus.

151 Seven genes were identified in the MD/FDP locus.

152 From baseline to month 24, mean FDP foveal sensitivity decreased in the placebo group (-

153 A higher mean FDP foveal sensitivity in the doxycycline group compared

154 e synthesis of 14,15-dimethyl-FDP, 12-methyl-FDP, 12-hydroxy-FDP, homo-FDP, and 15-methyl-FDP was als

155 FDP, 12-hydroxy-FDP, homo-FDP, and 15-methyl-FDP was also achieved.

156 ling free energies deltaG(Mn-PEP), deltaG(Mn-FDP), and deltaG(PEP-FDP) are -3.88, -1.09, and -0.22 kc

157 ized controlled trials comparing FDP with no FDP (nFDP) across the MEDLINE, Embase, and Cochrane Libr

158 3, 2021, for RCTs evaluating FDP versus non-FDP (nFDP).

159 Here, we document that this bioactivity of FDP is conserved in human FDP, is not limited to trophob

160 nfluencing factors of postural compliance of FDP was constructed based on the interview analysis.

161 studied the mechanism for the cyclization of FDP and the putative intermediate, nerolidyl diphosphate

162 ulene, which arises from 1,11-cyclization of FDP.

163 Each additional day of FDP was associated with improved odds of anatomic succes

164 The necessity and duration of FDP for FTMH closure remain contentious, with no consens

165 d on hole size, type of gas, and duration of FDP.

166 analysis and electron microscopy imaging of FDP indicate ca. 10 nm crystalline domains organized in

167 respond maximally, influenced the impact of FDP on perception, functional topography, and connectivi

168 In this study, the influence of FDP on the interactions of PEP and Mn2+ and the influenc

169 Breast MRI AP may be employed instead of FDP to identify breast cancer with similar diagnostic pe

170 n of Mn2+ to YPK enhances the interaction of FDP by -1.6 kcal/mol and the interaction of PEP by -2.8

171 luence of PEP and Mn2+ on the interaction of FDP with YPK were measured, where possible, by direct bi

172 l practices regarding the need and length of FDP recommended to patients after FTMH surgery.

173 ant difference was observed in the levels of FDP, D-dimer, and MPV among the three groups of the pati

174 fication through chemoproteomic profiling of FDP- and MP-modified proteins.

175 the average match score improvement ratio of FDP-M-net is 1.39%, U-finger is 14.62%, both of which ar

176 A significant reduction of FDP mean deviation (MD) was exhibited in PRP-treated pat

177 h, an updated estimate of the effect size of FDP on clinically important outcomes is critical to info

178 ion of the diferric and diferrous species of FDP.

179 ate indicated that the diferric structure of FDP prior to and immediately after turnover with NO are

180 n intermediate in the NOR catalytic cycle of FDPs.

181 hree-dimensional structures, particularly of FDPs with a clear preference toward either O2 or NO, two

182 iderably fewer plaque deposits were found on FDP (43%).

183 However, only FDP competently turns over NO to N2O.

184 T restored with fiber post and either SCs or FDPs was 69.2%.

185 te kinetic data for the interactions of PEP, FDP, and Mn2+ with yeast pyruvate kinase (YPK), we have

186 ct binding data for the interactions of PEP, FDP, and Mn2+ with YPK.

187 mol relative to the analogous YPK-Mn(2+)-PEP-FDP complex.

188 ltaG(Mn-PEP), deltaG(Mn-FDP), and deltaG(PEP-FDP) are -3.88, -1.09, and -0.22 kcal/mol, respectively.

189 and coupling free energy term, deltaG(Mn-PEP-FDP), indicates that simultaneous binding of Mn2+, PEP,

190 t sensitivity, frequency doubling perimetry (FDP), Humphrey visual fields, photostress recovery, and

191 ional factors (frequency doubling perimetry [FDP], Humphrey photopic Swedish Interactive Thresholding

192 and maturity, and fruit development period (FDP), defined as the duration between full bloom and mat

193 ompared the levels of plasma D-dimer, plasma FDPs, eosinophil counts, eosinophil cationic protein, an

194 Frequency-dependent plasticity (FDP) describes adaptation at the synapse in response to

195 77)Lu, the fractional decrease in platelets (FDP) correlates well with both the radioactive dose admi

196 ue data sets from the forest dynamics plots (FDP) network, which shed light on the factors responsibl

197 quantify, in sixteen forest diversity plots (FDPs) worldwide, highly significant negative density-dep

198 ast region perform in forest dynamics plots (FDPs) from global CTFS-ForestGEO network, we analyzed DN

199 achment (RRD) require face-down positioning (FDP) for 3-6 months or longer after pars plana vitrectom

200 ance of postoperative face-down positioning (FDP) to achieve anatomic and functional success after fu

201 and visual effects of facedown positioning (FDP) advice in patients undergoing vitrectomy with gas t

202 omodulin, fibrinolytic degradation products (FDP) of fibrin induce apoptotic cell death of a speciali

203 TT), fibrinogen/fibrin degradation products (FDP), and fibrinogen were used most frequently as DIC di

204 protein (CRP), fibrin degradation products (FDP), and heat shock protein 70 (HSP70) levels-would be

205 tective effects of fermented dairy products (FDPs) in an infection model, using the mouse pathogen Ci

206 Fibrin degradation products (FDPs) and interleukins 6 and 10 (IL-6 and IL-10) were un

207 ibrin generates fibrin degradation products (FDPs) with multiple biological activities in several cel

208 of D-dimer and fibrin degradation products (FDPs).

209 The macaque flexor digitorum profundus (FDP) consists of a muscle belly with four neuromuscular

210 ospital practices, the Final Degree Project (FDP) and the Objective Structured Clinical Examination (

211 ermutation-based false discovery proportion (FDP) estimation methods.

212 ls in patients with fixed dental prostheses (FDP), and effectiveness of computer-based training (CBT)

213 2) 3- to 4-unit PFM fixed dental prostheses (FDPs), with 1 healthy and 1 endodontically treated and f

214 Flavo-diiron proteins (FDPs) are non-heme iron containing enzymes that are wide

215 unique active site of flavo-diiron proteins (FDPs) consists of a nonheme diiron-carboxylate site prox

216 Flavodiiron proteins (FDPs) are a family of enzymes endowed with bona fide oxy

217 organism possesses two flavodiiron proteins (FDPs) belonging to classes A and F, which are known in o

218 Flavodiiron proteins (FDPs) catalyze reductive scavenging of dioxygen and nitr

219 Flavodiiron proteins (FDPs) constitute a group of modular enzymes widespread i

220 Flavodiiron proteins (FDPs) play important roles in the microbial nitrosative

221 The role of flavodiiron proteins (FDPs), originally called A-type flavoproteins or Flvs, i

222 Xes and multicomponent flavodiiron proteins (FDPs).

223 Cyanobacterial flavodiiron proteins (FDPs; A-type flavoprotein, Flv) comprise, besides the be

224 as four genes encoding flavodiiron proteins (FDPs; Flv1 to Flv4).

225 er was the regular full diagnostic protocol (FDP) analyzed.

226 ic accuracy of the full diagnostic protocol (FDP).

227 The findings support recommending FDP for patients with macular holes exceeding 400 mum pe

228 uctured interviews with patients who require FDP after SO tamponade.

229 PAI-1 mRNA, protein, and activity by soluble FDPs and fibrinogen in rat lung fibroblast monolayers.

230 lly sighted trained observers for SAP, SWAP, FDP, and GRP.

231 ductase domains in addition to an N-terminal FDP core.

232 atural fusion product between the N-terminal FDP, central rubredoxin (Rb), and C-terminal NADH:Rb oxi

233 s study provides low-certainty evidence that FDP improves the anatomic and visual outcomes of macular

234 We show that FDP extends to the cortical level and is influenced by c

235 Furthermore, study results suggest that FDP, which primarily measures inner retinal function, is

236 The FDP and D-dimer combination (n = 39) had the highest dia

237 The FDP group exhibited a mean improvement in postoperative

238 ast masses underwent MRI with the AP and the FDP.

239 studies revealed that HN is preferred at the FDP site, that HG is preferred at the GGDP site, and tha

240 90)Y, there was poor correlation between the FDP and the radioactive dose administered (r = 0.20) or

241 Al and Sn can be incorporated into the FDP zeolite framework to produce active and selective me

242 ostic accuracy was equivalent to that of the FDP and resulted in an additional cancer yield of 18.2 p

243 nsights into the spatial organization of the FDP core within this multidomain fusion protein.

244 curacy of 90.5%, 96.4%, and 94.4%, while the FDP showed a specificity, sensitivity, and accuracy of 9

245 terpretation of the complete AP, as with the FDP, allowed diagnosis of all cancers (11 [100%] of 11).

246 tis sp. PCC 6803 has four genes encoding the FDPs.

247 Unlike higher plants that lack the FDPs and use the Proton Gradient Regulation 5 to safegua

248 There was a visual benefit to FDP; however, the CIs included values of trivial clinica

249 thholding FDP was found to be noninferior to FDP for the study population as a whole (95% CI for adju

250 Withholding FDP was noninferior to FDP in holes </=400 mum in diameter.

251 e of the exceptions, at the Wind River (USA) FDP, reveal new details of a known allelopathic effect o

252 positive predictive value (PPV) of AP versus FDP were equivalent (94.3% v 93.9% and 24.4% v 23.4%, re

253 U-finger in SFinGe synthetic dataset, where FDP-M-net and U-finger are both convolutional neural net

254 ted odds ratio (OR) for primary closure with FDP versus nFDP was 2.41 (95% confidence interval [CI],

255 genesis gene CsNOT2a; CsNOT2a interacts with FDP.

256 Treatment of mice with FDP formulas A, B, and C or a control product did not af

257 Ninety-three patients with FDP were randomly allocated to one of three training gro

258 aque removal skills are low in patients with FDP.

259 Withholding FDP was noninferior to FDP in holes </=400 mum in diamet

260 Although withholding FDP was found to be noninferior to FDP for the study pop

261 m in diameter, noninferiority of withholding FDP could not be concluded.

262 mine the extent to which compartments within FDP act on single versus multiple digits, we stimulated