ライフサイエンスコーパス: FRP

1 FRP denotes 4 quadrants of root planing performed within

2 FRP's precursors could already interact with and regulat

3 FRP, which uses FMN as a cofactor to mediate the reducti

4 FRPs are typically formed via spontaneous single-electro

5 FRPs have been shown to interact with Wnt proteins and a

6 FRPs measured 24 to 72 hr after coronary ligation were 2

7 FRPs measured during acute ischemia shortened an average

8 f FMNH2 cofactor from FRP to luciferase in a FRP:luciferase noncovalent complex were retained by FRP-

9 The two components of a FRP exhibit orthogonal chemical properties and can often

10 An FRP derivative containing 2-thioFMN as the cofactor was

11 or photochemical) to promote an FLP into an FRP system.

12 e structural similarities between FRG(F) and FRP(H) and between L(F) and L(H), direct flavin product

13 isms were determined for the FRG(F)-L(F) and FRP(H)-L(F) coupled reactions.

14 or transfer was detected for FRG(F)-L(F) and FRP(H)-L(F).

15 one treatment center indicated that FDIS and FRP attained greater therapeutic improvements than PDIS

16 gnificantly lesser cytotoxicity than LRP and FRP; further, the replacement of leucines with valines a

17 harveyi cellular contents of luciferase and FRP were estimated to be 172 and 3 microM, respectively.

18 .8077-0.9617) have been observed for TAC and FRP with antiradical activity and total phenolics conten

19 -sectional size of the inner steel tube, and FRP thickness on the ultimate load-carrying capacity and

20 d 15-30 degrees C, the binding of FMN by apo-FRP was found to be noncooperative, exothermic, and prim

21 properties of binding of reduced FMN by apo-FRP were found to closely resemble those of FMN binding

22 he regulation of functional coupling between FRP(Vh) and luciferase, this study was carried out to ch

23 we established the relationship map between FRP parameter space and dispersity, further suggested th

24 Both FRP and luciferase within FRP-alphabeta were catalytical

25 icated that similar results were attained by FRP with and without adjunctive chemotherapy.

26 F-alpha, and IL-6 in macrophages followed by FRP, VRP, and ARP.

27 d flavin mononucleotide (FMNH2) generated by FRP must be supplied, through either free diffusion or d

28 regulated at the post-translational level by FRP and/or oligomerization.

29 each was critical in the binding of NADPH by FRP.

30 dicated that the bioluminescence produced by FRP-alphabeta without added flavin was derived from dire

31 ast, other OCP families are not regulated by FRP.

32 iferase noncovalent complex were retained by FRP-alphabeta.

33 sponse bias as well as a smaller and delayed FRP (indicative of disrupted reward learning) and reduce

34 Wnt family members in early Xenopus embryos, FRP antagonized Wnt-dependent duplication of the embryon

35 Overexpression of a cDNA encoding FRP-50 in an FA(C) cell line resulted in partial correct

36 ted and characterized a novel fusion enzyme, FRP-alphabeta, in which FRP was fused to the luciferase

37 used as a low-disturbance method to estimate FRP in tropical forests and peatlands.

38 However, few FRP estimates exist for tropical peatlands, with none fr

39 We find FRP of 2.6 +/- 0.3 Mg C ha(-1) yr(-1), 1.9 +/- 0.5 Mg C

40 alysis has only been clearly established for FRP(Vh).

41 punching shear strength prediction model for FRP-RC panels was constructed using XGBoost and compared

42 estigation of the mechanisms responsible for FRP inhibition revealed that FRP forms complexes with WN

43 V. harveyi luciferase but as a substrate for FRP(Vh) in the luciferase-coupled bioluminescent reactio

44 of a direct transfer of FMNH2 cofactor from FRP to luciferase in a FRP:luciferase noncovalent comple

45 Importantly, FRP-alphabeta gave a higher total quantum output without

46 delling techniques and their applications in FRP/RDRP of MVMs.

47 Significant conformational changes in FRP upon binding of FMN were indicated.

48 hancement ratio (epsilon(cc)/epsilon(co)) in FRP-wrapped elliptical concrete columns is crucial for o

49 and RCP 8.5) causes a widespread increase in FRP (113.5% increase in the area with FRP >= 0.3), and p

50 ate fluorescence anisotropy of eosin-labeled FRP, it was shown that luciferase formed a complex at 1:

51 The labeled FRP in either the holo- or apoenzyme form was similar to

52 r the holo- nor the apoenzyme of the labeled FRP in the dimeric form was effective in complexing with

53 nes with the IVS4 + 4 A to T mutation lacked FRP-50.

54 At submicromolar levels, FRP-alphabeta was significantly more active than an equa

55 We estimate the lifetime FRP benefits generated by major vaccines among individua

56 ty of FRP would be trapped in the luciferase/FRP complex.

57 on analysis, activity assays of FRP mutants, FRP:OCP docking simulations, and coimmunoprecipitation e

58 or apoenzyme form was similar to the native FRP in undergoing a monomer-dimer equilibrium.

59 higher than the 0.4 muM K(d) for the native FRP, whereas the k(cat) of these two variants were simil

60 Observed FRPs were used to infer action potential duration and T

61 d ESVs before and during coronary occlusion, FRP was -1.1+/-1.1 (+/-SD) mm Hg before versus 0.2+/-1.2

62 The OCP-FRP interaction exploits an ancient dimer interface in O

63 id conservation analysis, activity assays of FRP mutants, FRP:OCP docking simulations, and coimmunopr

64 a scheme that the reduced flavin cofactor of FRP is preferentially utilized by luciferase for light e

65 ffects of replacement of the FMN cofactor of FRP(H) and FRG(F) by 2-thioFMN were also characterized.

66 The bound FMN functions as a cofactor of FRP(Vh) in transferring reducing equivalents from NADPH

67 study can provide guidance for the design of FRP-RC slabs.

68 ther the apoenzyme or the holoenzyme form of FRP with K(d) values of 7 and 11 microM, respectively.

69 form, a tetramer, may be an inactive form of FRP.

70 lso discussed in relation to the function of FRP as a reduced flavin donor in the FRP-luciferase coup

71 There were no differences in serum levels of FRP and Dkk-1 between case subjects with incidence or pr

72 Baseline serum levels of FRP and Dkk-1 were measured by capture enzyme-linked imm

73 a trend for higher baseline serum levels of FRP to be associated with a reduced risk of incident RHO

74 There was no association of serum levels of FRP with progression of RHOA.

75 The vast majority of FRP would be trapped in the luciferase/FRP complex.

76 e kinetically deduced ping-pong mechanism of FRP is now supported by direct measurements of binding a

77 However, the kinetic mechanism of FRP was changed to a sequential pattern with a Km,FMN of

78 y more active than an equal molar mixture of FRP and luciferase in coupled bioluminescence without FM

79 in whereas bioluminescence from a mixture of FRP and luciferase with or without exogenously added fla

80 y protein (FRP), evolved when a precursor of FRP was horizontally acquired by cyanobacteria.

81 bound FMN in the reductive half-reaction of FRP(Vh).

82 Therefore, the overall catalytic reaction of FRP-alphabeta without any FMN addition closely mimics th

83 OCP, which also predates the recruitment of FRP into the photoprotection system.

84 Hence, the reduction of FRP(Vh)-bound FMN is not the committed step in coupling

85 rly calculate the punching shear strength of FRP-RC slabs.

86 concrete strength and the total thickness of FRP multiplied by its elastic modulus.

87 some other properties of a R203A variant of FRP(Vh) and an NADH/NADPH-utilizing flavin reductase fro

88 H bonds can be accomplished using a class of FRPs generated from disilazide donors and an N-oxoammoni

89 erspective, we will discuss the discovery of FRPs, their fundamental reactivity in chemical bond acti

90 Our study suggests that aftereffects on FRP may be an emergent property of the system that canno

91 y and collectively, showed a large impact on FRP and could avert ~200 million CHE cases across 52 Gav

92 Here we report on FRP using repeat photographs of roots from in situ trans

93 Here we report the expression of one FRP gene, Mfrzb1, in the rostral mesenchyme of the mandi

94 of administering full-mouth therapy (FDIS or FRP) is to eliminate or reduce bacterial reservoirs with

95 h a functional role may also exist for other FRP homologous proteins.

96 swamp estimate is similar to the only other FRP study in tropical peatlands, also hardwood-dominated

97 The Vibrio harveyi NADPH-FMN oxidoreductase (FRP) and the luciferase pair were chosen as a model for

98 Vibrio harveyi NADPH-FMN oxidoreductase (FRP) catalyzes flavin reduction by NADPH.

99 of Vibrio harveyi NADPH:FMN oxidoreductase (FRP) to luciferase for the coupled bioluminescence react

100 Vibrio harveyi NADPH:FMN oxidoreductase P (FRP(Vh)) is a homodimeric enzyme having a bound FMN per

101 harveyi NADPH-preferring flavin reductase P (FRP(H)) to the luciferase (L(H)) from the same bacterium

102 ), previously known as familial rectal pain (FRP, OMIM 167400), is an inherited disease causing inten

103 acid can generate a frustrated radical pair (FRP) depending on the substrate and energy required (the

104 generate a reactive frustrated radical pair (FRP).

105 Frustrated radical pairs (FRPs) describe the phenomenon that two distinct radicals

106 ve thus been named frustrated radical pairs (FRPs).

107 study of traditional frustrated Lewis pairs, FRPs have recently been shown to be capable of homolytic

108 s to measure behavioral free-running period (FRP), and then PER2::LUC bioluminescence from SCN, splee

109 , ventricular functional refractory periods (FRPs) were measured at five to eight epicardial, intramu

110 vestigate the flexion relaxation phenomenon (FRP).

111 peptides with leucine (LRP), phenylalanine (FRP), valine (VRP), and alanine (ARP) residues at these

112 isinfection (FDIS), full-mouth root planing (FRP), and partial-mouth disinfection (PDIS) to improve p

113 These new poly(FRP)s enable both catalytic hydrogenation and radical-me

114 polymeric frustrated radical pairs, or poly(FRP)s, by in situ photoinduction of FLP moieties, where

115 hybrid elliptical fiber-reinforced polymer (FRP)-concrete-steel double-skin tubular columns (DSTCs)

116 e application is a Fiber-Reinforced Polymer (FRP).

117 d modelling for free radical polymerization (FRP) and reversible-deactivation radical polymerizations

118 surfaces using free radical polymerization (FRP) offers a means to incorporate the diverse physicoch

119 challenge via free radical polymerizations (FRPs).

120 Soft fiber-reinforced polymers (FRPs), consisting of rubbery matrices and rigid fabrics,

121 mutation expressed a 50-kD FAC polypeptides, FRP-50 (FAC-related protein), shown to be an amino termi

122 The feedback-related positivity (FRP) in response to reward feedback was used as a neural

123 a control, non-treated forced roots powder (FRP-BE) was tested.

124 using burned area and fire radiative power (FRP) methods that rely on satellite products.

125 An increasing trend in fire radiative power (FRP) were found for Cambodia (p = 0.005), India (0.039),

126 nt capacity (TAC) and ferric reducing power (FRP) based on reactions with electrogenerated bromine an

127 A negative fully relaxed pressure (FRP) indicates the presence of restoring forces.

128 variation in the fire relative probability (FRP) change along the months, with October showing the h

129 blished a functional recombinant production (FRP) system to produce pure and functional HIV-1 intersu

130 matter may derive from fine root production (FRP).

131 Prolonging FRPs in the same area caused T-wave inversion in lead X

132 ential to provide financial risk protection (FRP) by preventing illnesses and associated healthcare c

133 The fluorescence recovery protein (FRP) detaches OCP1 from the PBS core, accelerating its b

134 protein, the fluorescence recovery protein (FRP), dislodges the active OCP(r) from the PBSs and acce

135 egulator, the fluorescence recovery protein (FRP), evolved when a precursor of FRP was horizontally a

136 he regulatory fluorescence recovery protein (FRP).

137 involves the fluorescence recovery protein (FRP).

138 e presence of fluorescence recovery protein (FRP).

139 aling antagonists, Frizzled-related protein (FRP) and Dkk-1, are associated with the development and

140 two members of the Frizzled-related protein (FRP) gene family that are thought to encode antagonists

141 is protein, called Frizzled-related protein (FRP), was first identified as a heparin-binding polypept

142 Frizzled related proteins (FRPs) comprise a family of secreted molecules that conta

143 izzled receptors, Frizzled-related proteins (FRPs), which contain the cysteine-rich domain of Frizzle

144 straightforward, twofold soak-wash protocol, FRP over the PDA-functionalized surfaces results in cova

145 These estimates fall within the published FRP range worldwide.

146 he propensity of PDA free radicals to quench FRP is studied using in situ (1)H nuclear magnetic reson

147 kinases, including Tor1p, Tor2p, FRAP/RAFT, FRP/ATR, ATM, Mec1p, Rad3, and Tel1p, function in signal

148 brio harveyi luciferase and flavin reductase FRP are, together, a two-component monooxygenase couple.

149 brio harveyi NADPH-specific flavin reductase FRP follows a ping-pong mechanism but switches to a sequ

150 ontaining encapsulated and free resveratrol (FRP), respectively.

151 ted did not correlate with behavioral rhythm FRP.

152 ationary Operational Environmental Satellite FRP observations (Fuel2Fire inventory, slope = 1.33 +/-

153 ary gas and aerosol emissions from satellite FRP observations, and we derive these values for many co

154 Serum FRP levels were measured by enzyme-linked immunosorbent

155 the Arg200Trp minor allele had higher serum FRP levels than controls who were homozygous for the maj

156 women, whereas the highest quartile of serum FRP levels tended to be associated with a modest reducti

157 Shortening FRPs in the anterolateral wall of the ventricle increase

158 Nevertheless, existing soft FRPs are relatively weak against crack propagation due t

159 In this work, a class of soft FRPs that possess high specific strength while simultane

160 verage normalized amplitude; and the spatial FRP onset was determined and expressed as percentage of

161 In biosynthetic studies, FRP was secreted but, like Wnts, tended to remain associ

162 Vaccines can provide substantial FRP benefits, particularly among the most disadvantaged

163 similar to the dimeric form of Synechocystis FRP.

164 ally, we demonstrated by cotransfection that FRP forms complexes with a prototype frizzled.

165 We demonstrated that FRP antagonizes the Wnt-induced increase in uncomplexed

166 We also found that FRP decreased with depth and was the highest during the

167 We showed further that FRP inhibits Wnt signaling in a paracrine mode using a T

168 These results indicate that FRP may function as an inhibitor of Wnt action during de

169 responsible for FRP inhibition revealed that FRP forms complexes with WNT-1 or WNT-2 through its CRD

170 FRPs containing different tags revealed that FRP itself forms complexes and that this ability is conf

171 We anticipate that FRPs will provide new reaction strategies for solving ch

172 Notable preliminary results suggest that FRPs may be useful reagents in chemical synthesis(6-8),

173 The FRP acts to dissociate the OCP from the phycobilisomes b

174 The FRP of SCN samples was negatively correlated with the FR

175 The FRP of the four peripheral oscillators tested did not co

176 Individuals with LBP and the FRP exhibited a delay of its onset compared to pain-free

177 identified sites of interaction between the FRP and OCP.

178 e binding of oxidized and reduced FMN by the FRP apoenzyme.

179 r back-conversion, lack of regulation by the FRP, a different oligomeric state (monomer compared to d

180 al recombination breakpoints from either the FRP system or dual infection cultures.

181 3% of the individuals with LBP exhibited the FRP.

182 Moreover, for the FRP, FMN at concentrations over 2 microM significantly i

183 between C1 and gp41 regions either from the FRP system or from the dual infection culture, and very

184 dditive exPlanations analysis identified the FRP thickness-elastic modulus product (t(f) x E(f)) and

185 er understanding the functions of FMN in the FRP holoenzyme, this study was undertaken to quantify an

186 tion of FRP as a reduced flavin donor in the FRP-luciferase couple.

187 e determined the 3D crystal structure of the FRP at 2.5 A resolution.

188 A 4.4-kb transcript of the FRP gene is present in many organs, both in the adult an

189 rstanding the physiological relevance of the FRP-mediated relaxation process.

190 The effective depth of the FRP-RC slabs is the most important and proportional to t

191 Remarkably, the FRP is found in two very different conformational and ol

192 Similar to the FRP(H)-L(H) couple, direct cofactor transfer was detecte

193 N samples was negatively correlated with the FRP of behavioral rhythms, replicating prior results in

194 gainst flavin substrate in reacting with the FRP reduced flavin cofactor.

195 ized amplitude compared to those without the FRP, but still greater than pain-free controls (signific

196 Conceptually, full-mouth therapy (FRP or FDIS) could reduce the number of patient visits a

197 tion to NADPH binding, NADP(+) also bound to FRP(Vh) in either the oxidized (K(d) 180 microM) or redu

198 ant-by-quadrant root planing was compared to FRP or FDIS with regard to PD reduction, gains of clinic

199 n DFC-BE (81.82 g/100 g DW) in comparison to FRP-BE (49.04 g/100 g DW).

200 if benefits induced beyond PDIS were due to FRP or administration of multifaceted intraoral chlorhex

201 d shown that those residues are essential to FRP activity.

202 CP1, including its regulation by Tolypothrix FRP, which we show is structurally similar to the dimeri

203 i are quite similar to that of the wild-type FRP(Vh), the reversal of the reduction of bound FMN was

204 cterize coupled luminescence reactions using FRP(H) and the Vibrio fischeri NAD(P)H-utilizing flavin

205 search sheds light on dispersity control via FRPs and creates a novel platform to investigate polymer

206 indings are consistent with a model by which FRP inhibits Wnt signaling through interactions with Wnt

207 novel fusion enzyme, FRP-alphabeta, in which FRP was fused to the luciferase alpha subunit.

208 Considering climate only, the area with FRP >= 0.3 (a threshold chosen based on the literature)

209 .5) causes a 21.3% increase in the area with FRP >= 0.3 in October by 2071-2100 compared to the basel

210 ase in FRP (113.5% increase in the area with FRP >= 0.3), and prolongs the fire season, displacing it

211 one causes a 10.6% increase in the area with FRP >= 0.3, while the worse-case land-use scenario ("Fra

212 ios causes a 39.1% increase in the area with FRP >= 0.3.

213 The bound FMN co-isolated with FRP, while acting as a genuine cofactor in the single-en

214 nism, a complex formation of luciferase with FRP is essential, but until now, no evidence for such a

215 ysis and design of composite structures with FRP-RC slabs.

216 Transfection analysis with FRPs containing different tags revealed that FRP itself

217 Both FRP and luciferase within FRP-alphabeta were catalytically active.

218 In this work, FRP was labeled at 1:1 molar ratio with the fluorophore