ライフサイエンスコーパス: FTMS

1 Thus, in an FTMS ion cell with added electron trapping electrodes, c

2 tion demonstrated that FIA-ESI-HRMS (MSX and FTMS) is applicable for quantification of FC and CE in s

3 ry and secondary alkoxides occurs under both FTMS and FA conditions.

4 ible obstacle to high-resolution analysis by FTMS.

5 m/z values below 1000 have been observed by FTMS of whole cells, this represents the first report of

6 need to be applied for CE quantification by FTMS to achieve accurate concentrations.

7 is - Fourier transform mass spectrometry (CE-FTMS) and showed a differential metabolic separation bet

8 cidated using HPLC ESI capillary-skimmer CID FTMS by correlating their fragmentation patterns with th

9 tial of MALDI-collision-induced dissociation-FTMS.

10 ially increases the capabilities of top down FTMS for the detailed structural characterization of lar

11 transform mass spectrometer (Orbitrap Elite FTMS).

12 Here we demonstrate an entirely FTMS-based analysis method with a 2.5-3.0-fold greater t

13 ESI-FTMS provides a universal method to achieve a direct and

14 igonucleotide products is mass mapped by ESI-FTMS analysis, which enables the unambiguous identificat

15 eated with ribonucleases and analyzed by ESI-FTMS to obtain the correct position of chemically modifi

16 on cross-linking strategies and top-down ESI-FTMS.

17 extracted, digested, and analyzed by LC-ESI-FTMS/MS to find highly conserved peptides as markers of

18 In particular, ESI-FTMS can be directly employed to monitor the conditions

19 High resolution ESI-FTMS analysis of the inactivated enzyme demonstrated tha

20 ion-Fourier transform mass spectrometry (ESI-FTMS) is employed in place of polyacrylamide gel electro

21 ion Fourier transform mass spectrometry (ESI-FTMS).

22 ion-Fourier transform mass spectrometry (ESI-FTMS).

23 ion-Fourier transform mass spectrometry (ESI-FTMS).

24 ion-Fourier transform mass spectrometry (ESI-FTMS).

25 oteins have been detected directly using ESI-FTMS (or MALDI-TOF), and the fractionation showed a peak

26 The application of an online FAIMS-FTMS coupling after photoionization for the analysis of

27 haracteristic is particularly beneficial for FTMS applications in which a sharp reduction of metastab

28 ight species presents a unique challenge for FTMS, as a result not only of the high cyclotron frequen

29 desorption/ionization (HP-MALDI) source for FTMS has recently been described.

30 This information is also accessible from FTMS mass spectra obtained in commonly used workflows di

31 s a control, accurate mass measurements from FTMS and collision-induced dissociation spectra, 11 nove

32 resolution precursor ion data obtained from FTMS mass spectra.

33 mprehensive analysis approach based on HILIC-FTMS was developed to concurrently examine polar metabol

34 e MeOH/ACN/Acetone extraction with the HILIC-FTMS method for metabolite profiling and smoking-related

35 The HILIC-FTMS method was developed using mixed standards of polar

36 HPLC-FTMS(n) analysis led to the annotation of 138 urinary me

37 d, namely, accurate mass fragmentation (HPLC-FTMS(n)) and mass-guided SPE-trapping of selected compou

38 The combination of the HPLC-FTMS(n) and HPLC-TOFMS-SPE-NMR platforms results in the

39 Hybrid FTMS instruments, such as the LTQ-FT and LTQ-Orbitrap, a

40 oughput proteomics measurements using hybrid FTMS instruments.

41 f (13)C into different metabolic pools by IC-FTMS or GC-MS.

42 gnal detection periods typically employed in FTMS, viz., shorter than 6 s.

43 lly linked with all emerging product ions in FTMS(2) experiments.

44 Selected method applications include FTMS analysis of crude oil fractions as well as tandem M

45 btained by analogous electrospray ionization-FTMS experiments, with no evidence of either metastable

46 new method was developed and optimized by LC-FTMS.

47 clotron resonance mass spectrometry (nano-LC-FTMS).

48 tion of thousands of peptides in a single LC-FTMS analysis by comparing accurate molecular mass and L

49 matches of compounds were elucidated via LC-FTMS for the best-performing extracts.

50 rap-Fourier transform mass spectrometry (LTQ-FTMS).

51 rap-Fourier transform mass spectrometer (LTQ/FTMS).

52 ddition, the performance of the new HP-MALDI FTMS configuration and its potential application for hig

53 on is the evaluation of the current HP-MALDI FTMS configuration.

54 n Fourier transform mass spectrometry (MALDI FTMS) for neuropeptide analysis of complex tissue sample

55 MALDI-FTMS also provided information regarding E. coli lipids

56 MALDI-FTMS can clearly separate the molecular ion peaks from a

57 Finally, the potential of AP MALDI-FTMS for the high-resolution screening of complex mixtur

58 In our hands, AP MALDI-FTMS has enabled the analysis of complex peptide mixture

59 with minimal cleanup and monitored by MALDI-FTMS to elucidate the oligosaccharide sequence.

60 ons in the 5000 to 10,000 m/z range by MALDI-FTMS using whole cells.

61 It is shown that accurate mass MALDI-FTMS can be used to characterize specific ribosomal prot

62 Previous MALDI-FTMS studies of oligonucleotides had two limitations: (1

63 n Fourier transform mass spectrometry (MALDI-FTMS).

64 n-Fourier transform mass spectrometry (MALDI-FTMS).

65 With the anion dopants, the MALDI-FTMS signals are shown to have a linear relationship wit

66 tics of crustacean neuropeptides under MALDI-FTMS conditions and show how fragments formed by Asp-Xxx

67 nal structural information relative to MALDI/FTMS.

68 ional dissociation (HCD) Orbitrap tandem MS (FTMS(2)) analysis of ~5 ms.

69 d that, upon full scan Fourier transform MS (FTMS) quantification, CE species show substantial differ

70 ionization (ESI) to a Fourier transform MS (FTMS).

71 Fourier transform mass spectrometry (nanoESI-FTMS).

72 exceptional m/ z resolution and accuracy of FTMS are indispensable for frontline biological and envi

73 n encrypted in DOM and assess the quality of FTMS-derived molecular formulas of complex mixtures in g

74 purified compounds were elucidated by use of FTMS and NMR.

75 sor ion scanning, higher resolution scans on FTMS instruments, and improved peptide quantitation.

76 meter (advanced quadrupole filter, optimized FTMS scan overhead) and new instrument control software

77 ly can be realized using high-field Orbitrap FTMS and/or future generation of ultrahigh magnetic fiel

78 spite being initially developed for Orbitrap FTMS, the method is likewise applicable for ion cyclotro

79 ster X2, coupled to a Q Exactive HF Orbitrap FTMS instrument.

80 acquired from 549 metabolites using Orbitrap FTMS(n).

81 analysis of petroleum samples with Orbitrap FTMS.

82 h, estuarine DOM samples were analyzed by OT-FTMS coupled to IC in negative mode and LC in positive m

83 With IC-OT-FTMS, a total of 1432 compounds were detected.

84 rbitrap Fusion Tribrid mass spectrometer (OT-FTMS), which assures high mass accuracy at every scan by

85 ntly below 1.0 ppm mass error, giving the OT-FTMS the potential of reaching mass accuracy of the Four

86 In UPLC-OT-FTMS, a total of 915 compounds were detected.

87 e I (42 kDa) yielded as many as 70 peptides, FTMS identification of the labeled peptide localized the

88 raw MS/MS data (obtained using a quadrupole-FTMS hybrid instrument) for one protein that differed fr

89 e to the poor performance of high-resolution FTMS for the analysis of larger proteoforms and the high

90 ewise applicable for ion cyclotron resonance FTMS.

91 a low-cost prototype for an external source FTMS instrument.

92 With the external ion source FTMS instrument, ions made by MALDI are injected at low

93 ch as a Fourier transform mass spectrometer (FTMS) allows accumulation of ions in the cell from m

94 source Fourier transform mass spectrometer (FTMS) equipped with matrix-assisted laser desorption/ion

95 n (ESI) Fourier transform mass spectrometer (FTMS) to characterize nucleic acid substrates modified b

96 eved by Fourier transform mass spectrometry (FTMS) allowed for the incorporation of substrates with s

97 solving Fourier Transform mass spectrometry (FTMS) allows to distinguish between most isobaric compou

98 ng both Fourier transform mass spectrometry (FTMS) and the flowing afterglow (FA) technique.

99 Fourier transform mass spectrometry (FTMS) enables comprehensive analysis of complex molecula

100 m ion cyclotron resonance mass spectrometry (FTMS) has been applied to the direct analysis of crustac

101 ed with Fourier transform mass spectrometry (FTMS) has proven to be a useful technique for the studie

102 olution Fourier transform mass spectrometry (FTMS) has revealed unprecedented details of natural comp

103 nces in Fourier transform mass spectrometry (FTMS) instrumentation, top-down proteomics (TDP) is curr

104 ccuracy Fourier transform mass spectrometry (FTMS) is becoming increasingly attractive due to its spe

105 I) with Fourier transform mass spectrometry (FTMS) is described, and its significance for the high-re

106 henated Fourier transform mass spectrometry (FTMS) methods affords additional information about compl

107 tion of Fourier transform mass spectrometry (FTMS) to analysis of bacterial proteins directly from wh

108 n (ESI) Fourier transform mass spectrometry (FTMS) to assess the ability of a series of nucleic acid

109 olution Fourier transform mass spectrometry (FTMS), and fragmentation analysis.

110 (SPLC), Fourier transform mass spectrometry (FTMS), data-independent acquisition (DIA) with nozzle-sk

111 (MALDI)-Fourier transform mass spectrometry (FTMS).

112 rbitrap Fourier transform mass spectrometry (FTMS).

113 yzed by Fourier-transform mass spectrometry (FTMS).

114 rved by Fourier transform mass spectrometry (FTMS).

115 n (ESI) Fourier transform mass spectrometry (FTMS).

116 n (ESI) Fourier transform mass spectrometry (FTMS).

117 collected and processed with a Spectroswiss FTMS Booster X2 data acquisition system.

118 ly modified states from a single 90 min SPLC-FTMS run on approximately 0.5 mug of material.

119 Extension of such FTMS-based studies will allow the direct visualization o

120 the high-performance data acquisition system FTMS Booster X2 provided access to the unreduced data in

121 n using an external data acquisition system, FTMS Booster X2, coupled to a Q Exactive HF Orbitrap FTM

122 However, the speed of tandem FTMS analysis severely limits the competitive advantage

123 inimized, and DNA ions can be trapped in the FTMS analyzer cell for greater than 50 s.

124 Use of dimethyl disulfide in the FTMS and evaluation of ion residence time in the FA lead

125 CAD or IRMPD of these ions collected in the FTMS cell.

126 pairs, vs 66 for CAD and 50 for IRMPD in the FTMS cell.

127 s are desorbed, ionized, and detected in the FTMS with >70 000 resolving power.

128 Furthermore, when the FTMS has a vibrationally cooled MALDI ion source, fragil

129 aneous detection of molecular hydrogen using FTMS and demonstrate the experimental conditions necessa

130 st intensely ionized serum metabolites using FTMS and tandem mass spectrometry was reported.

131 a 1.7 mm cryo-microprobe in combination with FTMS, exciton coupled CD, and stereochemical correlation

132 coupling of laser desorption techniques with FTMS was realized two decades ago, several different sol