ライフサイエンスコーパス: FTO

1 composite modified fluorine doped tin oxide (FTO).

2 by fat mass and obesity-associated protein (FTO).

3 ctrochemical platform (PGL1M3R/CdS/Ni(OH)(2)/FTO).

4 tin oxide coated glass slide (CdS/Ni(OH)(2)/FTO).

5 c insight into the therapeutic mechanisms of FTO.

6 either CRISPR/Cas9 or shRNA targeted against Fto.

7 levels in/near LEP, SLC32A1, GCKR, CCNL1 and FTO.

8 reveal the successful grafting of ERGO-CS/Hb/FTO.

9 ents were significantly associated with BMI (FTO: 0.43 [95% confidence interval, 0.32-0.54] kg/m(2) p

10 a in the maternal genome at ZNF831/20q13 and FTO/16q12.

11 yers coated Au, 2D material (black-P) coated FTO, (3-aminophenyl) triethoxysilane modified TiO2, were

12 adipocyte proliferation, and is increased in FTO-4 MEFs and reduced in FTO-KO MEFs.

13 predicted from these findings, fat pads from FTO-4 mice fed a high-fat diet show more numerous adipoc

14 asts (MEFs) derived from FTO overexpression (FTO-4) mice exhibit increased potential for adipogenic d

15 Overall, carriers of the FTO A allele had an increased risk of CHD (odds ratio, 1

16 its fat mass and obesity-associated protein (FTO) activity, thereby increasing global N(6)-methyladen

17 HE, LRRC14, FUK, NPRL3, EVL, SLCO3A1, PSMA4, FTO, ADCK5, PP1R16A and TEP1.

18 study, we demonstrate that gene variants of FTO affect dopamine (D2)-dependent midbrain brain respon

19 Here we demonstrate that variants of FTO affect dopamine-dependent midbrain brain responses a

20 in the fat mass and obesity-associated gene (FTO) affect adiposity in an age-dependent fashion in chi

21 TRMT10A, interacts with an mRNA demethylase FTO (ALKBH9), both in vitro and inside cells.

22 Our data indicate that the FTO allele associated with obesity represses mitochondri

23 risk allele rs8050136 in the first intron of FTO alters a regulatory element recognized by the transc

24 Fat mass and obesity-associated protein (FTO), an RNA N(6)-methyladenosine (m(6)A) demethylase, p

25 FTO, an mRNA N(6)-methyladenosine (m(6)A) demethylase, w

26 foundational mechanistic differences between FTO and ALKBH5 that promote these distinct biochemical o

27 ically, downregulation of m(6)A demethylases FTO and ALKBH5 was sufficient to increase FZD10 mRNA m(6

28 Two major human AlkB family members, FTO and ALKBH5, both act as oxidative demethylases of N6

29 target of obesity-associated variants within FTO and represents a novel determinant of body mass and

30 , thereby leading to decreased expression of FTO and retinitis pigmentosa GTPase regulator-interactin

31 influence on adiposity via remote effects on Fto and Rpgrip1l expression.

32 mely FB23 and FB23-2, which directly bind to FTO and selectively inhibit FTO's m(6)A demethylase acti

33 In vivo, the expression of Fto and the m(6)A methyltransferase, Mettl3 correlated w

34 In Stage 1, two known (FTO and TMEM18) and six novel (PEX2, MTFR2, SSFA2, IARS2

35 of BMI and diabetes in genes TFAP2B, TCF7L2, FTO and ZC3H4.

36 atio, 1.15 (1.04-1.26) per kg/m(2), P=0.005 (FTO) and 1.11 (1.05-1.17) per kg/m(2), P<0.001 (BMI gene

37 , CDK10, MYH7B, SLC45A2, MTAP, ATM, CLPTM1L, FTO, and CASP8) that have previously been published with

38 TTL3 and METTL14 and demethylases ALKBH5 and FTO, and knockdown of methyltransferases increases, whil

39 significant overlap of associated mRNAs with FTO, and these mRNAs have accelerated decay rates potent

40 In vivo manipulation of CUX1, Fto, and/or Rpgrip1l expression in mice affected adiposi

41 we demonstrate that the splicing effects of FTO are dependent on the catalytic activity in vivo and

42 besity-associated noncoding sequences within FTO are functionally connected, at megabase distances, w

43 c lethal partner of VHL because deletions of FTO are mutually exclusive with VHL loss in pan cancer d

44 Given the role of FTO as a demethylase of N6-methyladenosine (m6A), we wen

45 de analysis of RNA demethylation and uncover FTO as a potent regulator of nuclear mRNA processing eve

46 These findings identify FTO as a potential HIF-independent therapeutic target fo

47 We identify endothelial FTO as a previously unknown central regulator of both ob

48 These data identify endothelial FTO as a previously unknown regulator in the development

49 MiSL identified FTO as a synthetic lethal partner of VHL because deletio

50 d type and HIF-deficient tumors, identifying FTO as an HIF-independent vulnerability of VHL-deficient

51 Our findings demonstrate a crucial role of FTO as an m(6)A demethylase in promoting melanoma tumori

52 The discovery of FTO as the first m6A mRNA demethylase established the co

53 is suggested for developing next-generation FTO as well as other TCO films with better than ever con

54 Here we show that FTO, as an m(6)A demethylase, plays a critical oncogenic

55 s of this study indicate that the effects of FTO-associated SNPs on energy homeostasis are due in par

56 o phosphodiesterase genes (PDE1C and PDE4B), FTO augmented second messenger 3', 5'-cyclic adenosine m

57 e spectroscopy signal of the Cu(3)VSe(4 )NSs-FTO based electrochemical cell fits an equivalent circui

58 reduced graphene oxide-chitosan (ERGO-CS/Hb/FTO) based biocompatible coatings.

59 We show that FTO binds preferentially to pre-mRNAs in intronic region

60 ine mammalian AlkB homologs exist (ALKBH1-8, FTO), but only a subset functions as DNA/RNA repair enzy

61 FTO is a druggable target and that targeting FTO by small-molecule inhibitors holds potential to trea

62 We modulated expression of FTO by using adeno-associated virus serotype 9 (in vivo)

63 he Fluorine doped tin oxide glass electrode (FTO) by drop-casting method for better immobilization of

64 , the fabricated champion device-1(c): Glass/FTO/c-TiO(2)/mp-TiO(2)/CH(3)NH(3)PbI(3-x)Cl(x)/EC-GC10@C

65 g glucose levels may amplify obesity-risk in FTO carriers and lead to an exaggerated weight gain over

66 CEA consisted of a Fluorine-doped Tin Oxide (FTO) conductive glass substrate - connected to the negat

67 We find that FTO deficiency could reduce the proliferation and neuron

68 Our results indicate that Fto deficiency increases the expression of genes related

69 In Fto-deficient arteries, microarray analysis identified u

70 ovel finding of increased Irx3 expression in Fto-deficient mice after high-fat feeding indicating a c

71 We generated endothelial Fto-deficient mice and analyzed the impact of obesity on

72 ection in resistance arteries of endothelial Fto-deficient mice on high-fat diet; conversely, direct

73 Wild type and Fto-deficient mice were exposed to standard or high-fat

74 umorigenesis in vivo, both of which required FTO demethylase activity.

75 emonstrates the functional importance of the FTO-dependent cardiac m6A methylome in cardiac contracti

76 Mimicking FTO depletion, FB23-2 dramatically suppresses proliferat

77 While the loss of endothelial FTO did not influence the development of obesity and dys

78 nd offer insight into potential link between FTO, dietary protein intake and adiposity.

79 depletion and pharmacological inhibition of FTO dramatically attenuate leukemia stem/initiating cell

80 in the fat mass and obesity-associated gene (FTO) drive the development of obesity in humans are poor

81 gether, these results show the importance of FTO during memory formation and, furthermore, implicate

82 activity has been suggested to attenuate the FTO effect on obesity, but it is unknown whether this is

83 Vitamin D status significantly modified FTO effects (P for interaction = 0.02).

84 Fluorine doped tin oxide (FTO) electrochemical immunosensor has been developed for

85 The ssDNA-nanocomposite modified FTO electrode exhibited optimum current within 5s, at pH

86 By fabricating Fe2O3NPs/rGO/PEDOT modified FTO electrode for determining ACh level in serum samples

87 eNHCPZn to photoinject charges into a SnO(2)/FTO electrode in a dye-sensitized solar cell (DSSC) arch

88 surface of ZnO/Pt-Pd nanocomposites modified FTO electrode.

89 ene pyrrole onto a fluorine-doped tin oxide (FTO) electrode allowed the targeted orientation of the f

90 The fat mass and obesity-associated gene (FTO) encodes an m6A RNA demethylase that controls mRNA p

91 FTO enhances leukemic oncogene-mediated cell transformat

92 demethylation profile that resembles that of FTO, establishing the importance of this residue in the

93 aste responsiveness, risk allele carriers of FTO exhibit dose-dependent increments in both impulsivit

94 y promoting Fto mRNA degradation, and forced FTO expression in macrophages mimics the phenotype of ME

95 Moreover, FTO expression is increased in VHL-deficient ccRCC tumor

96 Here, we show that FTO expression is suppressed in ovarian tumors and cance

97 between the obesity-associated variants and FTO expression or function has been made.

98 TeNPs/FTO fabricated at applied potential of -1.40 V showed an

99 ociation between the rs993609 variant of the FTO (fat mass and obesity associated) gene and body mass

100 us studies could prove a fundamental role of FTO (fat mass and obesity-associated protein) within obe

101 Here, we show that the FTO (fat mass and obesity-associated protein), an m6A de

102 ethyltransferase-like 3) and the demethylase FTO (fat mass and obesity-associated protein).

103 e of the best characterized RNA demethylase, FTO (fat mass and obesity-associated) in memory.

104 study, we prepare fluorine doped tin oxide (FTO) films by chemical vapor deposition with inclusions

105 intake, and corroborating earlier FGF21 and FTO findings.

106 highlights the broad potential of targeting FTO for cancer therapy.

107 R8U8, AKAP6, MC4R and SPECC1L-ADORA2A); (iv) FTO for SSBs.

108 in/near HSD17B11, VCAN, ADAMTSL3, IRS1, and FTO for total lean body mass and for three single-nucleo

109 d transcripts by limiting the m(6)A 'eraser' FTO from demethylation.

110 sus m6A motifs required for demethylation by Fto Fto KO osteoblasts were more susceptible to genotoxi

111 These data suggest that FTO functions intrinsically in osteoblasts through Hspa1

112 commonly carried obesity-risk variant in the FTO gene (rs1421085 single-nucleotide polymorphism) infl

113 Common variants in the FTO gene are associated with adiposity in children and y

114 ers (AA/AT) and nonrisk carriers (TT) of the FTO gene for analyses.

115 Our results provide suggestive evidence that FTO gene is associated with lean mass.

116 ucleotide polymorphism rs11642841 within the FTO gene on chromosome 16 (P = 3.8 x 10-8) and many sugg

117 that obesity-related risk allele carriers of FTO gene show dose-dependent increments in body mass ind

118 FTO gene variants have been associated with obesity phen

119 identify associations between lean mass and FTO gene, we performed a genome-wide association study (

120 isk carriers than in nonrisk carriers of the FTO gene.

121 ions in the fat mass and obesity-associated (FTO) gene are associated with obesity.

122 ions in the fat mass and obesity-associated (FTO) gene are linked to obesity.

123 isms in the fat mass and obesity-associated (FTO) gene have been associated with obesity in humans.

124 tron of the fat mass and obesity-associated (FTO) gene have the largest effect.

125 Fat mass and obesity-associated (FTO) gene is a candidate gene of obesity.

126 fect of the fat mass and obesity-associated (FTO) gene on adiposity is well established, there is a l

127 The fat mass and obesity-associated (FTO) gene plays a pivotal role in regulating body weight

128 isms in the fat mass and obesity-associated (FTO) gene represent common alleles that are strongly ass

129 1812 in the fat mass and obesity-associated (FTO) gene was genotyped using the Illumina PsychArray Be

130 609 in the fat mass- and obesity-associated (FTO) gene was recently shown to affect appetite, and the

131 Two genetic instruments for BMI were used: FTO genotype (rs1558902) and a BMI gene score comprising

132 We examined the interaction between FTO genotype and protein intake on the long-term changes

133 d adiposity measures were found, none of the FTO genotype by PA interaction assessments revealed nomi

134 ormation on fat-mass and obesity-associated (FTO) genotype risk had a greater effect on a reduction o

135 h significant associations between the three FTO genotypes and adiposity measures were found, none of

136 1-x)N composite thin films are fabricated on FTO glass by a facile, low-cost and scalable aerosol ass

137 de of poly(3,4-ethylenedioxythiophene) on an FTO glass modified by a plastic antibody of 3,4-ethylene

138 oparticles (AuNPs)/fluorine doped tin oxide (FTO) glass electrode.

139 nO/Pt-Pd) modified fluorine doped tin oxide (FTO) glass plate was fabricated for detection of consens

140 sensing element is then closed using a cover FTO-glass, hold in place with a clip, connected to the p

141 characterized the phenotype of mice lacking Fto globally (Fto (KO) ) or selectively in osteoblasts (

142 FTO/GNS/uPAR-Ab/uPA-Ag immunosensor displayed acceptable

143 In this study, a novel ultrasensitive FTO graphene nanosheets based electrode was used as a wo

144 Here we report that FTO has a role in white adipose tissue which modifies it

145 We discovered that FTO has decreased expression in failing mammalian hearts

146 human fat mass- and obesity-associated gene Fto have been linked with higher body mass index, but th

147 per 1-U increase, P<0.001) and incident AF (FTO, hazard ratio, 1.07 [1.02-1.11] per A-allele, P=0.00

148 2HG in inhibiting proliferation/survival of FTO-high cancer cells via targeting FTO/m(6)A/MYC/CEBPA

149 ing glucose or triglycerides can amplify the FTO impact on BMI.

150 r suppressor function of the RNA demethylase FTO implicates m(6)A RNA modifications in the regulation

151 To examine the role of FTO in bone, we characterized the phenotype of mice lack

152 Improving expression of FTO in failing mouse hearts attenuated the ischemia-indu

153 The role of FTO in neurodevelopment and neurogenesis, however, remai

154 y unappreciated tumor suppressor function of FTO in ovarian CSC mediated through inhibition of cAMP s

155 es in animals suggest the potential roles of FTO in regulating food intake.

156 on between VHL and the m(6)A RNA demethylase FTO in renal cell carcinoma.

157 ures to study the functional role of m6A and FTO in the heart and in cardiomyocytes.

158 Furthermore, targeted knockdown of FTO in the mPFC led to enhanced consolidation of cued fe

159 Knocking down the m(6)A demethylase FTO in the mPFC, which increases total m(6)A level, resu

160 Knockdown of FTO increases m(6)A methylation in the critical protumor

161 by fat mass and obesity-associated protein (FTO) increases melanoma growth and decreases response to

162 , modulation of m(6)A by the RNA demethylase FTO influenced the degradation profiles of a subset of t

163 FTO influences adipogenesis by regulating events early i

164 However, it is unclear whether FTO influences longitudinal trajectories of adiposity an

165 FTO inhibited the self-renewal of ovarian CSC and suppre

166 Notably, FTO inhibition reduced the survival of both HIF wild typ

167 multiple orthogonal approaches revealed that FTO inhibition selectively reduces the growth and surviv

168 FTO inhibition sensitizes leukemia cells to T cell cytot

169 istance, and suggest that the combination of FTO inhibition with anti-PD-1 blockade may reduce the re

170 e was increased in obese human arteries with FTO inhibitors or prostaglandin D(2) application.

171 Here, we report two potent small-molecule FTO inhibitors that exhibit strong anti-tumor effects in

172 cer Cell, Huang et al. design small-molecule FTO inhibitors, FB23 and FB23-2, and demonstrate their p

173 onal design, we have developed two promising FTO inhibitors, namely FB23 and FB23-2, which directly b

174 , alpha-ketoglutarate dependent dioxygenase (FTO), interleukin 6 (IL6), insulin receptor (INSR), neur

175 at feeding indicating a complex link between FTO, IRX3 and fat metabolism.

176 Collectively, our data suggest that FTO is a druggable target and that targeting FTO by smal

177 FTO is a nuclear protein and its physiological function

178 e present study also demonstrates that TeNPs/FTO is a promising sensing material suitable for determi

179 Here we show that FTO is expressed in adult neural stem cells and neurons

180 We observed that FTO is expressed in the nuclei, dendrites and near dendr

181 FTO/sTiO2/mpTiO2/MAPI/Spiro-OMeTAD/Au, where FTO is fluorine-doped tin oxide, sTiO2 indicates solid-T

182 FTO is highly expressed in AMLs with t(11q23)/MLL rearra

183 FTO is induced by metabolic starvation stress through th

184 Variation in FTO is the most important common genetic determinant of

185 Fat mass and obesity-associated gene (FTO) is a member of the Fe (II)- and oxoglutarate-depend

186 he fat mass- and obesity-associated protein (FTO) is an m(6)A demethylase with oncogenic properties i

187 nic differentiation, while MEFs derived from FTO knockout (FTO-KO) mice show reduced adipogenesis.

188 FTO knockout (KO) results in substantial changes in pre-

189 The alternative splicing effects of FTO KO anti-correlate with METTL3 knockdown suggesting t

190 alized the DNA damage and apoptotic rates in Fto KO osteoblasts.

191 6A-linked DRACH motifs partially rescues the FTO KO phenotype in a reporter system.

192 the phenotype of mice lacking Fto globally (Fto (KO) ) or selectively in osteoblasts (Fto (Oc) (KO)

193 nd is increased in FTO-4 MEFs and reduced in FTO-KO MEFs.

194 ation, while MEFs derived from FTO knockout (FTO-KO) mice show reduced adipogenesis.

195 The loss of FTO leads to decreased brain size and body weight.

196 mechanistic insight into how upregulation of FTO leads to obesity.

197 The loss of FTO led to the altered expression of several key compone

198 FTO level is increased in human melanoma and enhances me

199 irectly test this, we artificially decreased FTO levels in dorsal hippocampus of otherwise normal (wi

200 r conditioning transiently (0.5 h) decreased Fto levels in these neurons, with the largest decrease i

201 vival of FTO-high cancer cells via targeting FTO/m(6)A/MYC/CEBPA signaling.

202 tworks for 4 known m6A (de)methylases, i.e., FTO, METTL3, METTL14 and WTAP.

203 on and sustains SOCS1 induction by promoting Fto mRNA degradation, and forced FTO expression in macro

204 r contextual fear conditioning suggests that FTO normally constrains memory formation.

205 Although the association of the FTO obesity locus with leptin levels is abolished by adj

206 these neurons, with the largest decrease in FTO observed near synapses.

207 The decrease in FTO observed shortly after contextual fear conditioning

208 induced greater DNA damage in osteoblast of Fto (Oc KO) mice compared to controls.

209 y (Fto (KO) ) or selectively in osteoblasts (Fto (Oc) (KO) ).

210 The effect of FTO on adipogenesis appears to be mediated via enhanced

211 se and triglyceride levels with rs9939609 in FTO on BMI.

212 ase complex), m(6)A demethylases (ALKBH5 and FTO), or m(6)A reader proteins (YTHDF1, YTHDF2, and YTHD

213 se embryonic fibroblasts (MEFs) derived from FTO overexpression (FTO-4) mice exhibit increased potent

214 icant transcriptomic changes associated with FTO overexpression and m(6)A loss involving stem cell si

215 In addition, we demonstrate that FTO overexpression in mouse models of myocardial infarct

216 s N (1)-methylguanosine (m(1)G) in tRNA, and FTO performs demethylation on N (6)-methyladenosine (m(6

217 The CdS/Ni(OH)(2)/FTO photoelectrochemical platform was modified with a sy

218 , the applied potential to the CdS/Ni(OH)(2)/FTO platform was also investigated.

219 lectrochemical response of the CdS/Ni(OH)(2)/FTO platform was optimized by evaluating the effects of

220 Our study demonstrates that FTO plays critical roles in cancer stem cell self-renewa

221 These results together suggest FTO plays important roles in neurogenesis, as well as in

222 n the fat mass- and obesity-associated gene (FTO) predisposing to obesity and diabetes mellitus have

223 FTO preferentially demethylates m(6)Am rather than N(6)-

224 Furthermore, loss of endothelial FTO prevented the development of obesity-induced hyperte

225 anistic basis of the association between the FTO region and obesity.

226 The FTO region harbors the strongest genetic association wit

227 Given that Fto regulates D2/3R signaling in mice, we tested in huma

228 on, where m6A demethylation by ALKBH5 versus FTO results in release of FA, an endogenous one-carbon u

229 in osteoblasts following acute disruption of Fto revealed changes in transcripts of Hspa1a and other

230 ants who were informed that they carried the FTO risk allele (level 3 AT/AA carriers) than in the non

231 e genotype-phenotype correlation between the FTO risk allele and BMI, with an observed inflection poi

232 in weight and WC at month 6 were greater for FTO risk carriers than for noncarriers in the level 3 gr

233 he first time the dynamic connection between FTO RNA binding and demethylation activity that influenc

234 There were allele-dosage effects on FTO, RPGRIP1L, and AKT-interacting protein (AKTIP) expre

235 of these genetic variations on hypothalamic FTO, RPGRIP1L, and possibly other genes.

236 een rs1432679 (EBF1), rs17817449 (MIR1972-2: FTO), rs12710696 (2p24.1), and rs3757318 (ESR1) and adju

237 xamine the evidence for interactions between FTO (rs1421085) and various lifestyle and environmental

238 In addition, subjects were genotyped for FTO rs17817449 (AA, n = 345 [35%]; AC/CA, n = 481 [48.8%

239 The association between FTO rs3751812 and BMI adjusted for premeditation remaine

240 The FTO rs3751812 minor allele T was associated with higher

241 4), p=0.05]; [CAPN10 (rs2975760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] an

242 FTO rs9939609 (T>A) polymorphism was genotyped in 2 Swed

243 Our data suggest that individuals with the FTO rs9939609 A allele might obtain more benefits in a r

244 FTO rs9939609 A-allele carriers have an increased CHD ri

245 Our data suggest that FTO rs9939609 affects child weight gain, and genotype ef

246 We investigated whether FTO rs9939609 and TCF7L2 rs7903146 modified the associat

247 However, the effects of the FTO rs9939609 genotype and exercise on BChE activity, AG

248 We assessed the effect of FTO rs9939609 on BMI and BMI-for-age Z score changes dur

249 tes, DNA was collected and genotyped for the FTO rs9939609 variant using real-time PCR.

250 sing a well-known obesity risk polymorphism (FTO rs9939609) in a sample of 78 children (ages 9-12 y),

251 the %SMM and SMI definitions of sarcopenia; FTO rs9939609, ESR1 rs4870044, NOS3 rs1799983 and TRHR r

252 760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] and [SLC30A8 (rs13266634), p=0

253 The fat mass and obesity-associated gene (FTO) rs9939609 A-allele is associated with higher acyl-g

254 directly bind to FTO and selectively inhibit FTO's m(6)A demethylase activity.

255 High levels of FTO sensitize leukemic cells to R-2HG, whereas hyperacti

256 Knockdown of FTO sensitizes melanoma cells to interferon gamma (IFNga

257 -catalytic performance of the proposed TeNPs/FTO sensor has been studied by cyclic voltammetry (CV) a

258 The proposed TeNPs/FTO sensor shows an excellent sensitivity of 757 uA mM(-

259 This PDNA modified electrode (PDNA/ZnO/Pt-Pd/FTO) served as a signal amplification platform for the d

260 the regions of PIAS1, RGN (two variants) and FTO show evidence of replication in the UK Biobank (Euro

261 29 single nucleotide polymorphisms (SNPs) in FTO significantly associated with sarcopenia (combined p

262 FTO (single nucleotide polymorphism rs9939609) was genot

263 The fat mass and obesity-related (FTO) single-nucleotide polymorphism (SNP) rs9939609 is a

264 n of the resulting fluorine-doped tin oxide (FTO)|SnO2/TiO2|-[Ru(a) (II)-Ru(b) (II)-OH2](4+)(Al2O3 or

265 An interaction between the FTO SNP and macronutrient intake for obesity was suggest

266 ciations between obesity and cataract, using FTO SNP rs9939609 as an instrumental variable in an MR a

267 Imputed dosage of the FTO SNP rs9939609 was used.

268 onium lead iodide (MAPI) cells of the design FTO/sTiO2/mpTiO2/MAPI/Spiro-OMeTAD/Au, where FTO is fluo

269 The combination of gold NIs on the FTO substrate, causing NIs size and pattern irregularity

270 and anatase TiO(2) nanowires (TNW) onto the FTO substrate, followed by decorating Au nanoparticles o

271 lectrodeposited on fluorine-doped tin oxide (FTO) substrate using [BMIM][Ac] ionic liquid at 90 degre

272 ensional arrays of these nanotubes formed on FTO substrates are applied as photoanode in a dye-sensit

273 Glass/fluorine-doped tin oxide (FTO) substrates have been used to electrodeposit the sem

274 Its electron relays were directed to the FTO surface, thus promoting DET.

275 characterize the nanostructured Te films on FTO surface.

276 ified the glutamine transporter SLC1A5 as an FTO target that promotes metabolic reprogramming and sur

277 ose to ADCY3, GNPDA2, TMEM18, SEC16B, FAIM2, FTO, TFAP2B, TNNI3K, MC4R, GPR61, LMX1B and OLFM4 associ

278 l-molecule inhibitors of the RNA demethylase FTO that demonstrate significant anti-tumor effects in v

279 Decreasing FTO using either method specifically enhanced contextual

280 Genetic inactivation of FTO using multiple orthogonal approaches revealed that F

281 We report interactions between the FTO variant and each of: frequency of alcohol consumptio

282 ciation between the BMI-increasing allele of FTO variant and higher dietary protein intake and offer

283 hed variants for blood pressure (BP) and the FTO variant has also been associated with body mass inde

284 The BMI-increasing allele of the FTO variant showed a significant association with higher

285 A influences and interactive effects between FTO variants and PA on measures of adiposity in Latinos.

286 determine whether individuals with specific FTO variants exhibit differential responses to PA interv

287 diposity measures are associated with PA and FTO variants in Latinos, but the impact of their interac

288 Furthermore, FTO variants modulate the connectivity in a basic reward

289 more, dynamic causal modeling confirmed that FTO variants modulate the connectivity in a basic reward

290 hysical activity (PA) modifies the effect of FTO variants on obesity in Latino populations.

291 The interactive relation among FTO variants, dietary intake and body mass index (BMI) i

292 ces, Cu(3)VSe(4) NSs thin-films deposited on FTO were subjected to photoelectrochemical testing, show

293 slide covered with fluorine-doped tin oxide (FTO), which acts as a biosensor.

294 In contrast to FTO, which follows a traditional oxidative N-demethylati

295 ark can be "erased" by the m(6)A demethylase FTO, which is commonly deregulated in acute myeloid leuk

296 s performed by the demethylation activity of FTO, which selectively demethylates cardiac contractile

297 itro demethylation by the m(6) A demethylase FTO with high reproducibility.

298 ucibly associated variants within introns of FTO with increased risk for obesity and type 2 diabetes

299 ed polyoxotitanate nanocrystals deposited on FTO working electrodes.

300 ice, we tested in humans whether variants in FTO would interact with a variant in the ANKK1 gene, whi