ライフサイエンスコーパス: Fe2

1 Fe2(SO4)3 is the sole terminal oxidant in this process.

2 Fe2+ in the sample partitioned into the film where it re

3 Fe2+-bearing materials in terrestrial sediments are typi

4 -134)N(epsilon)(-)...H-N(epsilon')(His-134')-Fe2', in which crystallographic C(2) axes pass equidista

5 -valent Fe1(III)(mu-OH(-))(mu-GluCO(2)(-))(2)Fe2(II) and Fe1(II)(mu-GluCO(2)(-))(2)Fe2(III)-OH(-) cor

6 (-))(2)Fe2(II) and Fe1(II)(mu-GluCO(2)(-))(2)Fe2(III)-OH(-) cores.

7 diiron(II) diiron(III) tetracarbonate Fe2(2+)Fe2(3+)C4O13, both phases containing CO4 tetrahedra.

8 computational models containing a (mu-oxo)2-Fe2(III/IV) core.

9 binuclear [2Fe] subcluster, namely: [NEt4]2[Fe2(adt)(CO)4(CN)2] (adt = [S-CH2-NH-CH2-S](2-)).

10 mbdaPP titration revealed an S = 1/2, Fe(3+)-Fe2+ (g < 2) species with an Eo' > +128 mV.

11 (Et4N)2[(57)Fe2(adt)(CN)2(CO)4] was then used for the maturation of

12 The precursor [(57)Fe2(adt)(CN)2(CO)4](2-) was synthesized from the (57)Fe

13 Overexpression of Ccc1, a Fe2+ and Mn2+ transporter that has been localized to Gol

14 propose that the rise of O2 on Earth drove a Fe2+ to Mg2+ substitution in proteins and nucleic acids,

15 substrate by the reduced O2 moiety to form a Fe2(III/III)-peroxyhemiacetal complex, which undergoes r

16 ith spectroscopic properties suggestive of a Fe2(III/III) complex with a bound peroxide.

17 The first example of such a Fe2(SR)2H2 species is provided by the complex [(term-H)(

18 site (the "H-cluster"), which consists of a [Fe2(CO)3(CN)2(dithiomethylamine)] subcluster covalently

19 acts with PEt3 to produce the stable adduct [Fe2(S2C2H4)(mu-CO)(CN)3(CO)2(PEt3)](-).

20 l(-1) K(-1)) to give the symmetrical adduct [Fe2(S2C3H6)(mu-NO)(CO)4(PMe3)2]BF4.

21 nines with Z indicate that the high affinity Fe2+ binding at AGGG involves two adjacent guanine N7 mo

22 ne of these is the key substrate-alkylperoxo-Fe2+ intermediate, which has been predicted, but not str

23 Hematite (alpha-Fe2 O3) is engineered to improve photoexcited electron-h

24 Although Fe2+ is far more soluble than Fe3+, it rapidly oxidizes

25 An Fe2+/oxygen-dependent enzyme, it converts p-hydroxypheny

26 okaryotic organism, has been described as an Fe2+-dependent bicupin dioxygenase.

27 ransfer reactions, which are catalyzed by an Fe2+ ion and two general acids/bases in the LuxS active

28 s parasites similarly and irreversibly in an Fe2+-dependent manner.

29 omplex with O2 results in accumulation of an Fe2(III/IV) cluster, termed X, which oxidizes the adjace

30 on as a repressor both in the presence of an Fe2+ cofactor and in its apo (non-Fe2+-bound) form.

31 e CxxC form could lead to coordination of an Fe2-S2 cluster in these proteins in vitro.

32 ine, or alanine leads to the formation of an Fe2-S2 cluster in this protein.

33 A spectral feature attributed to an Fe2+ phase is present in many locations in the Mawrth Va

34 As estimated by calcein and Fe2+ chelator, the mean +/- SD labile Fe2+ concentration

35 CO)Si:L (3) through insertion of both CO and Fe2 (CO)6 into the Si2 core, which represents the first

36 D spectroscopy, protein crystallography, and Fe2+ release rates.

37 l conductivity values of both Fe2(DSBDC) and Fe2(DOBDC) are approximately 6 orders of magnitude highe

38 ; protein ligands for each iron ion (Fe1 and Fe2) were also unequivocally identified and found to be

39 nsport assay, CorA cannot transport Fe2+ and Fe2+ does not potently inhibit CorA transport of 63Ni2+.

40 ctures and reactivities of relevant Mg2+ and Fe2+ complexes.

41 end on different transition metals, Mn2+ and Fe2+, respectively.

42 Redox reactions between CeO2 NPs and Fe2+ lead to the formation of 6-line ferrihydrite on the

43 Furthermore, both gamma-radiation and Fe2+-EDTA/H2O2 showed relatively modest effects of seque

44 xidation associated with gamma-radiation and Fe2+-EDTA/H2O2.

45 re protected from cytoplasmic reductants and Fe2+ release by the protein nanocage until iron need is

46 [Fe2(N-Et-HPTB)(O2CPh)(NO)2](BF4)2 (1a) and [Fe2(N-Et-HPTB)(DMF)2(NO)(OH)](BF4)3 (2a), are characteri

47 4', one being formally an imidazolate anion, Fe2-(His-134)N(epsilon)(-)...H-N(epsilon')(His-134')-Fe2

48 Life originated in an anoxic, Fe2+-rich environment.

49 in the A, B, or C sites affects the apparent Fe2+-binding stoichiometries at the unaltered sites.

50 Aqueous Fe2+ and NO2- reacted rapidly, producing N2O and generat

51 se oxides at different pH values and aqueous Fe2+ concentrations using mediated potentiometry.

52 ron oxides-hematite and goethite-and aqueous Fe2+ reached thermodynamic equilibrium over the course o

53 idized contaminants much faster than aqueous Fe2+ alone.

54 (EH0) values of 768 +/- 1 mV for the aqueous Fe2+-goethite redox couple and 769 +/- 2 mV for the aque

55 edox couple and 769 +/- 2 mV for the aqueous Fe2+-hematite redox couple.

56 nji (JMJ) family of histone demethylases are Fe2+- and alpha-ketoglutarate-dependent oxygenases that

57 iron oxide surfaces (i.e., oxide-associated Fe2+) often reduces oxidized contaminants much faster th

58 Thus, both the geometric rearrangement at Fe2 (observed in MCD) coupled with a more global conform

59 ng protein ferritin and activates the ATPase Fe2+-secreting pump, which decrease intracellular free F

60 as a proton surrogate and form a stable Au2 Fe2 complex, [(mu-SAuPPh3 )2 {Fe(CO)3 }2 ], analogous to

61 g and incomplete saturation of the available Fe2+ hemesites.

62 inds Fe2+, both A and B sites in EcFtnA bind Fe2+, implying a role for the C site in influencing the

63 e HuHF where only the A site initially binds Fe2+, both A and B sites in EcFtnA bind Fe2+, implying a

64 ent metal ion site that preferentially binds Fe2+ or Mn2+.

65 h a regulatory metal-binding site that binds Fe2+ (PerR:Zn,Fe) or Mn2+ (PerR: Zn,Mn).

66 observed for the RTGR sequence, which binds Fe2+ with negligible structural rearrangements.

67 of step 2 is significantly enhanced by both Fe2+ and Fe3+ chelators.

68 bulk electrical conductivity values of both Fe2(DSBDC) and Fe2(DOBDC) are approximately 6 orders of

69 y measurements demonstrating that PerR bound Fe2+ with higher affinity than Mn2+.

70 ecause oxidation at this site required bound Fe2+ in vitro, we suggest that treatment of cells with 1

71 m is proposed in which the active site-bound Fe2+ or Zn2+ serves as a Lewis acid to activate the 2-OH

72 wo of the residues that coordinate the bound Fe2+.

73 lution, which reveals a CO molecule bridging Fe2 and Fe6 of the FeMo-cofactor.

74 nter and is quenched to different extents by Fe2+ and Fe3+.

75 d in vivo by the Fenton reaction mediated by Fe2+ and cellular reductants such as NADH, which reduce

76 on delivery for ISC synthesis is mediated by Fe2+-loaded monomeric Yfh1.

77 The singly reduced catalyst [Fe2(bdt)(CO)6](-), a key intermediate in photocatalytic

78 shed from the two-electron reduced catalyst [Fe2(bdt)(CO)6](2-) that is obtained inevitably in the el

79 lytic cycle of a proton reduction catalyst, [Fe2(bdt)(CO)6] (bdt = benzenedithiolate), were investiga

80 ilirubin and that of decreased free cellular Fe2+, we questioned whether HO-1 would modulate the expr

81 Using 1H NMR to characterize Fe2+ binding within the duplex CGAGTTAGGGTAGC/GCTACCCTAA

82 rmation of micron-sized fibrous chukanovite (Fe2(OH)2CO3) particles.

83 dye-derivatized iron/sulfur/nitrosyl cluster Fe2(mu-RS)2(NO)4 (Fluor-RSE, RS = 2-thioethyl ester of f

84 se (RNR) houses a diferric tyrosyl cofactor (Fe2(III)-Y(*)) that initiates nucleotide reduction in th

85 d with the precursor of the native cofactor [Fe2(adt)(CO)4(CN)2](2-) as well as a non-natural variant

86 = -175 vs Ag/AgCl) ethanedithiolato complex Fe2(S2C2H4)(CO)2(dppv)2 (1) under a CO atmosphere yielde

87 The resulting hydride complex [Fe2(bdt)(CO)6H] is therefore likely to be an intermediat

88 tion of the diiron dinitrosyl model complex [Fe2(BPMP)(OPr)(NO)2](BPh4)2.

89 rally and electronically the parent complex [Fe2(bdt)(CO)6], with very similar carbonyl stretching fr

90 a nonheme mononitrosyl diiron(II) complex, [Fe2(N-Et-HPTB)(NO)(DMF)3](BF4)3 (2).

91 In solution, the compound [Fe2 L3 ](ClO4 )4 (1) preserves the magnetic properties a

92 a potent ferroxidase activity that converts Fe2+ to Fe3+ in the presence of molecular oxygen.

93 sesses an antiferromagnetically (AF) coupled Fe2(III/III) center with resolved subsites.

94 uctural framework compounds 1-M (M=Li+, Cu+, Fe2+, Co2+, Ni2+, Cu2+, Zn2+).

95 e nonbinding Zn2+ heme substitutes for deoxy Fe2+ heme, also permits direct measurement of O2 binding

96 bstituted with Zn2+-heme, an analog of deoxy Fe2+-heme.

97 evaluated, including the biphenyl derivative Fe2(dobpdc) (H4dobpdc = 4,4'-dihydroxy-[1,1'-biphenyl]-3

98 dicarboxylic acid), the terphenyl derivative Fe2(dotpdc) (H4dotpdc = 4,4''-dihydroxy-[1,1':4',1''-ter

99 = 1, 2, 3) with NOBF4 gave the derivatives [Fe2(S2C(n)H(2n))(CO)(5-x)(PMe3)x(NO)]BF4, which are elec

100 Heme-derived Fe2+ induces the expression of the iron-sequestering pro

101 ly isostructural but electronically distinct Fe2(mu-S) species.

102 The dinuclear DNIC Fe2(mu-CysS)2(NO)4, a Roussin's red salt ester (Cys-RSE)

103 (1Dy ), which contains a rhombus-shaped Dy2 Fe2 core, are described.

104 We hypothesize that on early Earth, Fe2+ was a ubiquitous cofactor for nucleic acids, with r

105 sesses iron transporters specific for either Fe2+ or Fe3+.

106 with simultaneous optical detection enables Fe2+ to be distinguished from Fe3+, which is the first s

107 s well described by the Freundlich equation (Fe2(SO4)3, log KF = 6.35, n = 1.51; CFH-12 (Fe oxyhydrox

108 Consequently, we directly examined Fe2+ transport and toxicity in wild-type versus corA cel

109 Although excess Fe2+ was slightly toxic to S. enterica serovar Typhimuri

110 The Fe1- - -Fe2 distance (3.6 A) in this latter site is significantl

111 The Fe1-Fe2 distance within the diiron site of M. thermoacetica

112 ron oxide lowering EH values of aqueous Fe3+/Fe2+ redox couples.

113 that various metal cations (principally Fe3+/Fe2+, Ni2+, and Cr3+) released from acid corrosion of th

114 species: powellite (CaMoO4), ferrimolybdite (Fe2(MoO4)3.8H2O), and molybdate adsorbed on ferrihydrite

115 Here, we report the ferrous (Fe2+) complexes of NP4 with NO, CO, and H2O formed after

116 ylethene spacer predictably forms a ferrous [Fe2 L3 ](4+) helicate exhibiting spin crossover (SCO).

117 However, for Fe2(SO4)3 and CFH-12 liming was also necessary to preven

118 Detection limits of 0.6 x 10(-6) M for Fe2+ and 2 x 10(-6) M for Fe3+ were obtained with 300 nm

119 at Asp-157 is not a coordination residue for Fe2+ and Hg2+ binding.

120 on sensor sensitivity and response time for Fe2+ were evaluated.

121 4, or Xe) as well as reacting with 5 to form Fe2(CO)9.

122 diiron(II) compounds of the general formula [Fe2([G-3]COO)4(4-RPy)2] were prepared, where [G-3]COO- i

123 1/3/7) are more reduced than the other four (Fe2/4/5/6).

124 re, we show that the metal-organic framework Fe2(dobdc) (dobdc(4-) = 2,5-dioxido-1,4-benzenedicarboxy

125 ic properties of the metal-organic framework Fe2(dobdc), containing open Fe(II) sites, include hydrox

126 A redox-active metal-organic framework, Fe2(dobpdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dica

127 Among these frameworks, Fe2(m-dobdc) displays the highest ethylene/ethane (>25)

128 ting pump, which decrease intracellular free Fe2+ content.

129 biocompatible magnesium shallow doped gamma-Fe2 O3 (Mg0.13 -gammaFe2 O3 ) SPNPs with exceptionally h

130 ons in octahedral site Fe vacancies of gamma-Fe2 O3 instead of well-known Fe3 O4 SPNPs.

131 )-NO > (Fe2+)-NO > (Fe2+)-CO > (Fe3+)-H2O > (Fe2+)-H2O.

132 he following order: (Fe3+)-NO > (Fe2+)-NO > (Fe2+)-CO > (Fe3+)-H2O > (Fe2+)-H2O.

133 n state in the following order: (Fe3+)-NO > (Fe2+)-NO > (Fe2+)-CO > (Fe3+)-H2O > (Fe2+)-H2O.

134 es is provided by the complex [(term-H)(mu-H)Fe2(pdt)(CO)(dppv)2] ([H1H](0)).

135 hich undergoes substitution to afford [(mu-H)Fe2(pdt)(CO)(NCMe)(dppv)2](+) ([H1(NCMe)](+)).

136 e mixed-valence diiron hydrido complex (mu-H)Fe2(pdt)(CO)2(dppv)2 ([H1](0), where pdt =1,3-propanedit

137 The synthesis begins with [(mu-H)Fe2(pdt)(CO)2(dppv)2](+) ([H1(CO)](+)), which undergoes

138 bimetallic triple-stranded ferro-helicates [Fe2(NN-NN)3](4+) incorporating the common NN-NN bis(bide

139 type of dietary iron source (ferritin, heme, Fe2+ ion, etc.), and of the interactions dependent on fo

140 ite the ribosome's early evolution in a high Fe2+ environment, and the continued use of Fe2+ by oblig

141 ation from cells grown under low O2 and high Fe2+ and (iv) a small fraction of Fe2+ that is associate

142 f Fe2+ by obligate anaerobes inhabiting high Fe2+ niches.

143 However, Fe2+ remains stable aerobically under acidic conditions,

144 Here, we show that (i) Fe2+ cleaves RNA by in-line cleavage, a non-oxidative me

145 If Fe2+ is bound (ARD'), the same substrates yield methylth

146 NR intermediate X, which contains an Fe1(III)Fe2(IV) center (where Fe1 is the iron site closer to Tyr

147 f YiiP(D157A) showed no detectable change in Fe2+ and Hg2+ calorimetric titrations, indicating that A

148 e a built-in potential as large as 0.8 eV in Fe2 O3-Cr2O3 SLs.

149 H293N, and H295N, expected to be involved in Fe2+ binding, resulted in reduced enzymatic activity but

150 Mg2+ can, relatively weakly, inhibit Fe2+ uptake, but inhibition is not dependent on the pres

151 n and/or by a decrease of free intracellular Fe2+ but probably not by biliverdin or carbon monoxide.

152 impact of redox reactions with ferrous ions (Fe2+) on the colloidal stability of CeO2 NPs.

153 pathway involving reaction of ferrous iron (Fe2+) with nitrite (NO2-), an intermediate in the denitr

154 free diffusion of intracellular labile iron (Fe2+) through ferroportin (FPN), the transporter on the

155 UOB is repressed at high pH by CpxAR, and is Fe2+-Fur repressed.

156 tra consistent with the formation of Se(IV), Fe2(SeO3)3, FeSe, FeSe2, and Se(0) on the G-ZVI.

157 in and Fe2+ chelator, the mean +/- SD labile Fe2+ concentration was significantly lower in hemoglobin

158 Treatment of ((tbs)LH2)Fe2 complex with divalent Mn source (Mn2(N(SiMe3)2)4) af

159 btained during the discharge processes of Li/Fe2(MoO4)3 and Na/Fe2(MoO4)3 cells respectively.

160 (discrete occupation) in partially lithiated Fe2(MoO4)3 and the one by one Na occupation (pseudo-cont

161 Thus, FeoAB, the major Fe2+ transporter of E. coli, operates anaerobically.

162 The nitric oxide-containing material, Fe2(NO)2(dobdc), steadily releases bound NO under humid

163 divalent transition metal starting materials Fe2(Mes)4 (Mes = mesityl) or Mn3(Mes)6 in the presence o

164 In this mechanism, Fe2+ is responsible for proton transfer between O1 and O

165 nt with full localization of charge for meta-Fe2 on to a single metal center, as compared with charge

166 zed shows that electron localization in meta-Fe2 is not determined by interactions with the Au(111) s

167 two dinuclear organometallic molecules, meta-Fe2 and para-Fe2, which have identical molecular formula

168 pecies, and STM images of mixed-valence meta-Fe2 show pronounced asymmetry in electronic state densit

169 ted by the lack of a detectable 1-micrometer Fe2+ absorption band in high-spatial-resolution spectra

170 yme classes are similarly activated by Mn2+, Fe2+, Co2+, Ni2+, Zn2+ and Cd2+, but their allosteric bi

171 porphyrin ring of heme into carbon monoxide, Fe2+, and biliverdin, which is then converted into bilir

172 nother equivalent of Fe(CO)5 to give L:Si[mu-Fe2 (CO)6 ](mu-CO)Si:L (3) through insertion of both CO

173 discharge processes of Li/Fe2(MoO4)3 and Na/Fe2(MoO4)3 cells respectively.

174 ence of an Fe2+ cofactor and in its apo (non-Fe2+-bound) form.

175 oximal conformation coupled with the nonheme Fe2+.

176 Binding of Zn2+ and Cd2+, but not Fe2+, Hg2+, Co2+, Ni2+, Mn2+, Ca2+, and Mg2+, protected

177 d-type strain was possible in the absence of Fe2+ and Mn2+ cations after a lag of about 15 h.

178 t sedimentation than those in the absence of Fe2+.

179 In the absence of Mn2+, the addition of Fe2+ alone extended the 15-h lag phase to 25 h.

180 ty could be restored only by the addition of Fe2+ to the apoenzyme but not by other metals including

181 (tbs)LH2)Mn2 with a stoichiometric amount of Fe2(Mes)4 (0.5 mol equiv) affords a mixture of both ((tb

182 Specifically, expanded analogues of Fe2(dobdc) (dobdc(4-) = 2,5-dioxido-1,4-benzenedicarboxy

183 ce of cyanide and tertiary phosphines and of Fe2(S2C2H4)(CO)4(PMe3)2 in the presence of cyanide affor

184 XAS data is consistent with an assignment of Fe2/Fe6 as an antiferromagnetically coupled diferric pai

185 gnificantly, the anion insertion behavior of Fe2(dobpdc) enabled its use in the construction of a dua

186 for the C site in influencing the binding of Fe2+ at the B site of the di-iron center of EcFtnA.

187 The binding of Fe2+ to RGGG contrasts with that previously observed for

188 nizing radiation and the Fenton chemistry of Fe2+-EDTA/H2O2 poses a challenge to defining the locatio

189 and was proportional to the concentration of Fe2+ in the sample.

190 Possible contributions of Fe2+ as a ribosomal cofactor have been largely overlooke

191 A crystal of Fe2+-containing homoprotocatechuate 2,3-dioxygenase was

192 Treatment with vitamin C, a co-factor of Fe2(+) and alpha-KG-dependent dioxygenases, mimics TET2

193 dicarboxylic acid) leads to the formation of Fe2(DSBDC), an analogue of M2(DOBDC) (MOF-74, DOBDC(4-)

194 2 and high Fe2+ and (iv) a small fraction of Fe2+ that is associated with the ribosome is not exchang

195 an ability of CorA to mediate the influx of Fe2+.

196 sing Zn2+, a potent competitive inhibitor of Fe2+ binding and oxidation, that the fluorescence respon

197 bathophenanthroline suggests involvement of Fe2+.

198 gand, we obtained an unsymmetrical isomer of Fe2(S2C2H4)(mu-CO)(CN)2(PPh3)2(CO)2, as confirmed crysta

199 ions confirm that the most stable isomers of Fe2(S2C2H4)(mu-CO)(CN)2(PMe3)2(CO)2 have cyanide trans t

200 Four isomers of Fe2(S2C2H4)(mu-CO)(CN)2(PMe3)2(CO)2 were observed, the i

201 otif (facial triad) found in the majority of Fe2+-dependent oxygenases.

202 ecovery of the quench following oxidation of Fe2+ to Fe3+ at the ferroxidase center was not observed,

203 ly coupled with the binding and oxidation of Fe2+.

204 Paramagnetism of Fe2+ renders the active site of ARD' inaccessible to sta

205 ironment and, in particular, the presence of Fe2+ and/or Fe3+ chelators can influence significantly t

206 susceptible to reduction in the presence of Fe2+ chelators.

207 thout alpha-ketoglutarate in the presence of Fe2+ have been determined by X-ray crystallography.

208 of the cluster, resulting in the release of Fe2+, generating a [3Fe-4S]1+ cluster intermediate, and

209 tnB serves as a facile cellular reservoir of Fe2+.

210 interaction at the dioxygen binding site of Fe2.

211 we describe the first thermodynamic study of Fe2+ binding to EcFtnA and its variants to determine the

212 hing the high-spin to low-spin transition of Fe2+ at about 60 GPa, we observed enhanced absorption in

213 Treatment of Fe2(S2C(n)H(2n))(CO)(6-x)(PMe3)x compounds (n = 2, 3; x

214 h Fe2+ environment, and the continued use of Fe2+ by obligate anaerobes inhabiting high Fe2+ niches.

215 For the disproportionation rate constant of [Fe2(bdt)(CO)6](-), an upper limit on the order of 10(7)

216 ordination chemistry involving formation of [Fe2(bipy)4O(H2O)2]4+ as well as Fe(bipy)3(3+) in the fil

217 Two isomers of [Fe2(S2C3H6)(CO)3(PMe3)2(NO)]BF4 were characterized spect

218 Oxidation of [Fe2(S2C2H4)(CN)2(CO)4](2-) in the presence of cyanide an

219 copic analyses following the oxygenation of [Fe2([G-3]COO)4(4-PPy)2], where 4-PPy is 4-pyrrolidinopyr

220 Reaction of [Fe2(N-Et-HPTB)(CH3COS)](BF4)2 (1) with (NO)(BF4) produce

221 vitably in the electrochemical reduction of [Fe2(bdt)(CO)6].

222 estimated, which precludes a major role of [Fe2(bdt)(CO)6](2-) in photoinduced proton reduction cycl

223 t reorientation of the terminal glutamate on Fe2 reproduces the spectral perturbations in MCD.

224 Bilirubin and/or Fe2+ chelation mimicked the effects of HO-1, whereas bil

225 1 equiv of Zn2+, Cd2+, Co2+, Mn2+, Ni2+, or Fe2+.

226 Through systematic studies of orthorhombic Fe2(MoO4)3 electrode, two distinct guest ion occupation

227 nanometers) suggests that the ferrous oxide (Fe2+) content of silicates in average surface material i

228 to oxidative stress to sequester and oxidize Fe2+, which would otherwise lead to hydroxyl radicals th

229 )) as the cluster is converted to the mu-oxo-Fe2(III/III) product.

230 onucleotide reductase (RNR) employs a mu-oxo-Fe2(III/III)/tyrosyl radical cofactor in its beta subuni

231 -1alpha in the presence of molecular oxygen, Fe2+, alpha-ketoglutarate, and ascorbate.

232 organometallic molecules, meta-Fe2 and para-Fe2, which have identical molecular formulas but differ

233 ocalization over both metal centers for para-Fe2.

234 ion, the observation that mixed-valence para-Fe2 is delocalized shows that electron localization in m

235 In contrast, images of mixed-valence para-Fe2 show that the electronic state density remains symme

236 The results revealed a consistent pattern; Fe2+-EDTA and gamma-radiation generated MDA but not base

237 y under acidic conditions, although a low-pH Fe2+ importer has not been previously identified.

238 ain latent abilities to revert to primordial Fe2+-based states when exposed to pre-GOE conditions.

239 protonation of a coordinated OH-, to produce Fe2+ coordinated by H2O.

240 In the uptake of Fe3+, Fre1p produces Fe2+ that is a substrate for Fet3p; the Fe3+ produced by

241 Acids with pK(a) </= 12.7 protonate [Fe2(bdt)(CO)6](-) with bimolecular rate constants of 4 x

242 tes, include hydroxylation of phenol by pure Fe2(dobdc) and hydroxylation of ethane by its magnesium-

243 A 1.1 A resolution crystal structure of Q69E-Fe2+SOD indicates that Glu69 accepts a strong H-bond fro

244 t measurement of O2 binding to the remaining Fe2+ hemesites within the symmetrically ligated Hb tetra

245 In this model, Mg2+ replaced Fe2+ as the primary cofactor for nucleic acids in parall

246 Here, we report Fe2(BDP)3 (BDP(2-) = 1,4-benzenedipyrazolate), a highly

247 MptA was found to require Fe2+ for activity.

248 The enzyme requires Fe2+ as a cofactor and is inactivated by 4-chloro-3-hydr

249 urally related to Roussin's Red Ester (RRE, [Fe2 (NO)4 (Cys)2 ]) and Roussin's Black Salt (RBS, [Fe4

250 RNR-beta cofactor, reaction of the protein's Fe2(II/II) complex with O2 results in accumulation of an

251 unsaturated redox-active metal cation sites, Fe2(dobdc) (dobdc(4-) = 2,5-dioxido-1,4-benzenedicarboxy

252 ccupation) at 8d sites in partially sodiated Fe2(MoO4)3 are obtained during the discharge processes o

253 Two non-heme iron-nitrosyl species, [Fe2(N-Et-HPTB)(O2CPh)(NO)2](BF4)2 (1a) and [Fe2(N-Et-HPT

254 From UV/vis and IR spectroscopy, [Fe2(bdt)(CO)6](-) is readily distinguished from the two-

255 Structurally [Fe2(bdt)(CO)6](-) is characterized by a rather asymmetri

256 The binuclear subsite Fe2(adt)(CO)3(CN)2 is attached through a bridging cystei

257 of cells with 10 mM H2O2 released sufficient Fe2+ into the cytosol to effect a transition of PerR fro

258 2, and diiron(II) diiron(III) tetracarbonate Fe2(2+)Fe2(3+)C4O13, both phases containing CO4 tetrahed

259 copic characterization of the tetracarbonyl [Fe2(S2C2H4)(mu-CO)(CN)3(CO)3](-).

260 nylation also afforded the new tetracyanide [Fe2(S2C2H4)(mu-CO)(CN)4(CO)2]2-.

261 id not restore the activity, indicating that Fe2+ is the metal ion essential for the isomerohydrolase

262 ticular, numerous studies have observed that Fe2+ associated with iron oxide surfaces (i.e., oxide-as

263 -containing (Z) variants of it, we show that Fe2+ binds preferentially at the GGG sequence, most stro

264 Results show that Fe2+ can indeed substitute for Mg2+ in catalytic functio

265 modifies its lipid-A by hydroxylation by the Fe2+/alpha-ketoglutarate-dependent dioxygenase enzyme (L

266 surface are protonated, which allows for the Fe2+ to be released into the solution as a hydroxide.

267 ibuted to d-d orbital charge transfer in the Fe2+ ion.

268 that they are sensitive to the nature of the Fe2 core bridges and provide the basis for interpreting

269 es of N2 depending on the redox state of the Fe2(mu-H)2 unit.

270 ons strongly depend on the speciation of the Fe2+ and Fe3+ phases, although the underlying reasons re

271 (-1), nearly 40-fold higher than that of the Fe2+-containing enzyme and similar in magnitude to that

272 PvcB protein confirms it is a member of the Fe2+/alpha-ketoglutarate-dependent oxygenase family of e

273 planes bridging pairs of "anchor" Fe on the Fe2,3,6,7 face of FeMo-co.

274 -1 and a working electrode, we show that the Fe2+/Fe3+ couple in SWa-1 is redox-active over a large r

275 to be unusually sensitive to nicking via the Fe2+-mediated Fenton reaction.

276 iopropionate, and carbon monoxide, while the Fe2+-bound FeARD' catalyzes the on-pathway formation of

277 y upon exposure to air or treatment with the Fe2+ ion chelator bathophenanthroline.

278 ites in the pH range of 6.5-7.5, ascribed to Fe2+ binding, first at the A and then the B sites.

279 eating space for molecular oxygen to bind to Fe2.

280 In contrast to Fe2(S2C3H6)(CO)4(PMe3)2, the bis(PMe3) nitrosyl complexe

281 eductants such as NADH, which reduce Fe3+ to Fe2+ and allow the recycling of iron.

282 etween the His-134 imidazole ring ligated to Fe2 of the [2Fe-2S] cluster and its symmetry partner, Hi

283 ca serovar Typhimurium markedly resistant to Fe2+-mediated toxicity.

284 irect transport assay, CorA cannot transport Fe2+ and Fe2+ does not potently inhibit CorA transport o

285 We conclude that CorA does not transport Fe2+ and that the relationship, if any, between iron tox

286 , an RNA polymerase and a DNA ligase, to use Fe2+ in place of Mg2+ as a cofactor during catalysis.

287 structure of ARD' has been determined using Fe2+ binding parameters determined by X-ray absorption s

288 double-exchange coupling in a mixed-valence Fe2 complex is demonstrated.

289 (CN)2](2-) as well as a non-natural variant [Fe2(pdt)(CO)4(CN)2](2-) in which the bridging amine func

290 Thus, while Fe2+ adversely affects the transition from lag phase to

291 Computation explains why Fe2+ can be a more potent cofactor than Mg2+ in a variet

292 eoxygenation of the Diels-Alder adducts with Fe2(CO)9 followed by oxidative aromatization with 2,3-di

293 olubilized, reconstituted anaerobically with Fe2+, Fe3+, and S2-, and characterized by Mossbauer, EPR

294 ii) functional ribosomes are associated with Fe2+ after purification from cells grown under low O2 an

295 divalent cations is >200 times greater with Fe2+ than with Mg2+, (iii) functional ribosomes are asso

296 d isomers elute first from a bed packed with Fe2(BDP)3, followed by the monobranched isomers and fina

297 tivated enzyme is activated by reaction with Fe2+ and dithiothreitol in the absence of air.

298 Addition of Mn2+ alone or together with Fe2+ allowed prompt and rapid growth.

299 )2(dppv)2 (1) under a CO atmosphere yielded [Fe2(S2C2H4)(mu-CO)(CO)2(dppv)2](+) ([1(CO)](+)), a model

300 ed active enzymes, but the addition of Zn2+, Fe2+, and Cd2+ did not increase quercetinase activity to