ライフサイエンスコーパス: GPI-anchored protein

1 ocompatibility complex (MHC class I) Qa-2 (a GPI-anchored protein).

2 ow, conclusively, that human nyctalopin is a GPI anchored protein.

3 same rate as that seen for a DRM-associated GPI-anchored protein.

4 ecause it is a glycosylphosphatidylinositol (GPI)-anchored protein.

5 (PrP(C)) is a glycosylphosphatidylinositol (GPI)-anchored protein.

6 isfolding of a glycosylphosphatidylinositol (GPI)-anchored protein.

7 thus leading to greatly reduced activity on GPI-anchored proteins.

8 , which presumably increases its activity on GPI-anchored proteins.

9 ction at the omega+2 position in C. albicans GPI-anchored proteins.

10 s found in aerolysin overlays used to detect GPI-anchored proteins.

11 r glycosylinositolphospholipids (GIPLs), and GPI-anchored proteins.

12 nt cells that are defective in production of GPI-anchored proteins.

13 normal levels of related glycoconjugates and GPI-anchored proteins.

14 the two toxins bind to different subsets of GPI-anchored proteins.

15 malian cells recognize and degrade misfolded GPI-anchored proteins.

16 ls is an absence or marked deficiency of all GPI-anchored proteins.

17 ls showed decreased cell surface presence of GPI-anchored proteins.

18 lipid rafts and the membrane organization of GPI-anchored proteins.

19 or decreased cell surface expression of all GPI-anchored proteins.

20 ursors and restores C-terminal processing of GPI-anchored proteins.

21 to a physiologic role of naturally occurring GPI-anchored proteins.

22 in other glycosylation pathways or encoding GPI-anchored proteins.

23 the plasma membrane by examining the flow of GPI-anchored proteins.

24 protein partially rescued the deficiency of GPI-anchored proteins.

25 es have been implicated in the biogenesis of GPI-anchored proteins.

26 s enzyme, leading to reduced accumulation of GPI-anchored proteins.

27 ial effects on the uptake of transferrin and GPI-anchored proteins.

28 IGA-null cells showed partial restoration of GPI-anchored proteins.

29 osis that requires the direct cooperation of GPI-anchored proteins.

30 port and transport to the plasma membrane of GPI-anchored proteins.

31 ane topology, but we find that they can form GPI-anchored proteins.

32 ure domain in the metabolism of misprocessed GPI-anchored proteins.

33 ak activity on glycosylphosphatidylinositol (GPI)-anchored proteins.

34 ma membrane of glycosylphosphatidylinositol (GPI)-anchored proteins.

35 s dominated by glycosylphosphatidylinositol (GPI)-anchored proteins.

36 the sorting of glycosylphosphatidylinositol (GPI)-anchored proteins.

37 e deficient in glycosylphosphatidylinositol (GPI)-anchored proteins.

38 icient in all glycosyl phosphatidylinositol (GPI)-anchored proteins.

39 rties of three glycosylphosphatidylinositol (GPI)-anchored proteins.

40 d GM1 but not glycosyl-phosphatidylinositol (GPI)-anchored proteins.

41 also endowed with glycophosphatidylinositol (GPI)-anchored proteins.

42 association of glycosylphosphatidylinositol (GPI)-anchored proteins.

43 is of glycosylphosphatidylinisotol-anchored (GPI-anchored) proteins.

44 LEI (LRE)-LIKE GLYCOSYLPHOSPHATIDYLINOSITOL (GPI)-ANCHORED PROTEIN 1 (LLG1) to regulate immune signal

45 Null mutants of LORELEI-like-GPI-anchored protein 1 (LLG1), the closest relative of L

46 ol-anchored proteins (GPI-APs), LORELEI-like-GPI-anchored protein 2 (LLG2) and LLG3, as co-receptors

47 and acceptor-labeled antibodies against the GPI-anchored protein 5' nucleotidase (5' NT) at the apic

48 ncentrate much more in lipid rafts marked by GPI-anchored proteins (5' nucleotidase and folate recept

49 Glycophosphatidylinositol (GPI)-anchored proteins account for 26-35% of the Candida

50 by Triton X-100, had the same effect on the GPI-anchored protein alkaline phosphatase (PLAP) in SCRL

51 sistance was much higher than expected for a GPI-anchored protein alone and submicron domains of even

52 We show that diffusion of GPI-anchored proteins also becomes temperature dependent

53 kers, such as glycosyl phosphatidylinositol (GPI)-anchored proteins and glycosphingolipids, are incom

54 oteins such as glycosylphosphatidylinositol (GPI)-anchored proteins and nonreceptor tyrosine kinases

55 FRalpha is a GPI-anchored protein and a component of the caveolae fra

56 have now used FRET to study three different GPI-anchored proteins and a GSL endogenous to several di

57 take, including tubular membranes containing GPI-anchored proteins and dorsal membrane ruffles.

58 Analysis for the co-expression of specific GPI-anchored proteins and ecto-calreticulin in cells tha

59 ursors necessary for the proper targeting of GPI-anchored proteins and for parasite motility.

60 teins, which are receptors for the export of GPI-anchored proteins and have been shown to bind a spec

61 the quality control pathways for unprocessed GPI-anchored proteins and identify transamidation of the

62 The results suggest a role for GPI-anchored proteins and lipid rafts in root-hair tip g

63 th lipid raft microdomains in the absence of GPI-anchored proteins and suggest that association of th

64 iscriminate between plasma membrane-resident GPI-anchored proteins and those transferred to the cell

65 Thus cell surface diffusion of GPI-anchored proteins and transmembrane proteins that as

66 In an effort to identify GPI-anchored proteins and understand the possible role o

67 like GPI-anchored protein); At5g49270 (COBL9 GPI-anchored protein) and At5g65090 (inositol-1,4,5 trip

68 the putative GSL-enriched domains, Thy-1, a GPI-anchored protein, and GM1, a GSL, were followed with

69 gulation of the urokinase receptor (uPAR), a GPI-anchored protein, and in turn increased STAT-3 phosp

70 t seen after cross-linkage of Thy-1, another GPI-anchored protein, and were dependent on the GPI anch

71 rafts" enriched in glycosphingolipids (GSL), GPI-anchored proteins, and cholesterol have been propose

72 ated by lipid packing defects, possibly near GPI-anchored proteins, and the protein diffuses on the m

73 elated clinically, and glycophosphoinositol (GPI)-anchored protein (AP)-deficient cells can be found

74 crase isomaltase and alkaline phosphatase (a GPI-anchored protein) appeared partially depolarized in

75 -glycoside at 4 degrees C (representative of GPI-anchored proteins), appeared partially redistributed

76 direct interaction between p24delta5 and the GPI-anchored protein arabinogalactan protein4 (AGP4).

77 Glycosylphosphatidylinositol (GPI)-anchored proteins are abundantly expressed in the i

78 Glycosylphosphatidylinositol (GPI)-anchored proteins are cell surface-localized protei

79 Glycosylphosphatidylinositol (GPI)-anchored proteins are critical for embryogenesis, n

80 These glycosylphosphatidylinositol (GPI)-anchored proteins are expressed in distinct neurona

81 h cross-linked glycosylphosphatidylinositol (GPI)-anchored proteins are immobilized has been a myster

82 Glycosylphosphatidylinositol (GPI)-anchored proteins are important for virulence of ma

83 determine if glycosyl-phosphatidylinositol (GPI)-anchored proteins are involved in mammalian fertili

84 Glycosylphosphatidylinositol (GPI)-anchored proteins are nonmembrane spanning cell sur

85 Glycosylphosphatidylinositol (GPI)-anchored proteins are synthesized as precursor prot

86 Glycosylphosphatidylinositol (GPI)-anchored proteins are synthesized on membrane-bound

87 Glycosylphosphatidylinositol (GPI)-anchored proteins are ubiquitously expressed in the

88 Here we show that GPI-anchored proteins are associated with alpha subunits

89 We also showed that two additional GPI-anchored proteins are detergent-insoluble in SCRLs a

90 ortant for various biological processes, but GPI-anchored proteins are difficult to study.

91 e for endocytosis in T.brucei and hence that GPI-anchored proteins are endocytosed by clathrin-depend

92 We presented evidence that GPI-anchored proteins are insoluble because they associa

93 unction of HYAL2 is currently unknown, other GPI-anchored proteins are involved in signal transductio

94 immunochemical and functional criteria that GPI-anchored proteins are physically associated with G p

95 teins are degraded by proteasomes, misfolded GPI-anchored proteins are primarily degraded in lysosome

96 observed in the Deltagpi7 mutant, indicating GPI-anchored proteins are required for immune evasion.

97 We first investigated whether GPI-anchored proteins are required for VacA toxicity by

98 GPI-anchored proteins are structurally and functionally

99 The mechanisms by which T. gondii GPI-anchored proteins are synthesized and transported th

100 tic changes in glycosylphosphatidylinositol (GPI)-anchored protein arrangement under varying perturba

101 re enriched in glycosylphosphatidylinositol (GPI)-anchored proteins, as well as proteins involved in

102 on channel protein in any tissue, and that a GPI-anchored protein associates with an HCN channel subu

103 ned as membrane domains containing clustered GPI-anchored proteins at the cell surface.

104 erophosphoryl diester phosphodiesterase-like GPI-anchored protein); At5g49270 (COBL9 GPI-anchored pro

105 f sphingolipids is specific for transport of GPI-anchored proteins because no effect on the rate of t

106 We propose that saponin solubilizes GPI-anchored proteins because the lipid composition of c

107 ng which time it may cleave approximately 10 GPI-anchored proteins before dissociating.

108 tors, including folate receptor (FR) beta, a GPI-anchored protein belonging to the folate receptor fa

109 Previous studies demonstrated that HJV is a GPI-anchored protein, binds the proteins neogenin and bo

110 vious work suggests that Emm is located on a GPI-anchored protein, but the antigenic epitope and gene

111 PNT acutely inhibited the synthesis of GPI-anchored proteins, but the synthesis was rapidly res

112 SEL1L-HRD1 ERAD attenuates the biogenesis of GPI-anchored proteins by specifically targeting PIGK for

113 toxin, or through removal of raft-associated GPI-anchored proteins by treatment with phosphatidylinos

114 cell membranes and allows solubilization of GPI-anchored proteins by Triton X-100, had the same effe

115 tabolic engineering of cell-surface GPIs and GPI-anchored proteins by using inositol derivatives carr

116 Cell-to-cell transfer of CD55 and CD59, 2 GPI-anchored proteins, by red cell microvesicles has bee

117 Glycosylphosphatidylinositol (GPI)-anchored proteins can be isolated from both cells a

118 DAF and other GPI-anchored proteins can be found in cholesterol-rich o

119 Among these advantages are that 1) GPI-anchored proteins can be painted onto cells that are

120 can be precisely controlled, and 4) multiple GPI-anchored proteins can be sequentially or concurrentl

121 Thus, cross-linked GPI-anchored proteins can diffuse through the membrane i

122 GPI-anchored proteins, candidate cargoes for alternate p

123 sis requires the interaction of CR3 with the GPI-anchored protein, CD14, independently of TLR/MyD88-i

124 There were significantly reduced levels of GPI-anchored proteins (CD55 and CD59) on the surface of

125 absence of two glycosylphosphatidylinositol (GPI)-anchored proteins, CD55 and CD59, leads to uncontro

126 y stained for glycosyl phosphatidylinositol (GPI)-anchored proteins; CD55 and CD59.

127 whereas a small number are restricted to the GPI-anchored protein CD59 for initial membrane recogniti

128 When the GPI-anchored proteins CD59, CD48, and Thy-1 were immunop

129 n transfer is not limited to PrP(C), another GPI-anchored protein, CD90, also transfers from the dono

130 We examined whether GPI-anchored proteins could be transferred in vivo to de

131 ired for the delivery of both lipids and the GPI-anchored protein Crh2 from the cortical ER to the pl

132 intrinsic signaling abilities of the apical GPI-anchored protein DAF to open the tight junction barr

133 Many CVBs also interact with the GPI-anchored protein decay-accelerating factor (DAF).

134 ereus PI-PLC abolished its ability to cleave GPI-anchored proteins, decreased its inhibitory effects,

135 he X-chromosomal gene PIGA is known to cause GPI-anchored protein deficiency, 2 such hits are require

136 ll percentage of glycophosphatidyl inositol (GPI)-anchored protein-deficient neutrophils over extende

137 rectly measure the colony-forming ability of GPI-anchored protein-deficient CD34+ cells, we separated

138 The presence of GPI-anchored protein-deficient cells in myelodysplasia p

139 of 39 (23%) patients with myelodysplasia had GPI-anchored protein-deficient cells.

140 Early emergence of GPI-anchored protein-deficient hematopoiesis in a patien

141 he cleavage of glycosylphosphatidylinositol (GPI)-anchored proteins, disrupted plasma membrane locali

142 lthough the majority of characterized fungal GPI-anchored proteins do in fact localize to the cell wa

143 oan parasites, glycosylphosphatidylinositol (GPI)-anchored proteins dominate the surface of Toxoplasm

144 Recently, the glycosylphosphatidylinositol (GPI)-anchored protein DRAGON was identified as a co-rece

145 R itineraries that not only shield misfolded GPI-anchored proteins during their trafficking, but also

146 n-independent endocytic pathway known as the GPI-anchored protein-enriched early endosomal compartmen

147 In contrast, we find that GPI-anchored proteins exhibit temperature-independent di

148 CD177 is a glycosylphosphatidylinositol (GPI)-anchored protein expressed by a variable proportion

149 hich is a small glycosylphosphatidylinositol(GPI)-anchored protein expressed on lymphocytes and media

150 The relationship between GPI-anchored protein expression and bone marrow (BM) fai

151 No patient with normal GPI-anchored protein expression at presentation develope

152 n PNH BM, 27% of CD34+ cells showed abnormal GPI-anchored protein expression when assessed by CD59 ex

153 tation is sufficient to abolish cell surface GPI-anchored protein expression.

154 er targeting, transport, and function of all GPI-anchored protein family members.

155 signaling system, axon guidance pathway, and GPI-anchored proteins family.

156 so allow the production of other recombinant GPI-anchored proteins for laboratory and clinical invest

157 bility to shed glycosylphosphatidylinositol (GPI)-anchored proteins from the cell surface.

158 rom Clostridium septicum was used to capture GPI-anchored proteins from human breast cancer tissues,

159 ects fertilization by specifically releasing GPI-anchored proteins from the oolemma.

160 In spite of its importance for GPI-anchored protein functions, our current knowledge of

161 procedure for database analysis to identify GPI-anchored proteins (GAP) based on their possession of

162 plex GPI-anchored peptides/glycopeptides and GPI-anchored proteins/glycoproteins.

163 ") enriched in glycosylphosphatidylinositol (GPI)-anchored proteins, glycosphingolipids, and choleste

164 by regulating the surface expression of the GPI-anchored protein, Glypican-(GPC)6.

165 ted to a human glycosylphosphatidylinositol (GPI)-anchored protein, GML.

166 and virulence factors, lipophosphoglycan and GPI-anchored proteins, gp63, and its virulence was not a

167 lls, misfolded glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) are cleared out of the

168 iosynthesis of glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) in the parasitic protoz

169 This novel GPI-anchored protein (GPI-80) is highly homologous with

170 g lead to decreased cell surface presence of GPI-anchored proteins (GPI-APs) and cause inherited GPI

171 GPI-anchored proteins (GPI-APs) are essential for plant

172 GPI-anchored proteins (GPI-APs) are ubiquitous and essen

173 teristics of fluorescent lipid analogues and GPI-anchored proteins (GPI-APs) in the live-cell plasma

174 GPIs is obligatory for parasite survival as GPI-anchored proteins (GPI-APs) play essential roles in

175 osphatidylinositols (GPIs) are essential for GPI-anchored proteins (GPI-APs), as the loose associatio

176 hat TMED9 plays a central role in the PQC of GPI-anchored proteins (GPI-APs).

177 re involved in biosynthesis and transport of GPI-anchored proteins (GPI-APs).

178 linositol-specific phospholipase C to remove GPI-anchored proteins greatly reduced HIV-1 sensitivity

179 lable individual samples showed that several GPI-anchored proteins had decreased cell-surface abundan

180 While several GPI-anchored proteins have been characterized, the biolo

181 While many GPI-anchored proteins have been characterized, the biolo

182 Here we show that different GPI-anchored proteins have different intracellular distr

183 bstituting 3'-mRNA end sequence of naturally GPI-anchored proteins (i.e., a sequence that contains th

184 (1) is defective in ER-to-Golgi transport of GPI-anchored proteins (i.e., Gas1p) while other proteins

185 proteins are GPI-anchored, and disruption of GPI-anchored proteins impairs cell wall integrity.

186 des a putative glycosylphosphatidylinositol (GPI)-anchored protein implicated in reception of the pol

187 cell biology of glycoinositol phospholipid (GPI)-anchored proteins in cultured cells, the in vivo fu

188 aft-associated glycosylphosphatidylinositol (GPI)-anchored proteins in the process by which Helicobac

189 To probe for microdomains enriched in GPI- anchored proteins in intact cell membranes, we used

190 allus suggest a differential requirement for GPI-anchored proteins in cell wall synthesis in these tw

191 demonstrated the efficacy of genes encoding GPI-anchored proteins in eliciting partially protective

192 sosomal GPIs are important for biogenesis of GPI-anchored proteins in L. major; (ii) sequestration of

193 Removal of GPI-anchored proteins in the wild-type strain by hydrofl

194 utility analyzing antibodies against CD52, a GPI-anchored protein, in its native membrane environment

195 f transport of glycosylphosphatidylinositol (GPI)-anchored proteins, including Cwp2 and Gas1/Gpg1, fr

196 Alpha-toxin binds to several parasite GPI-anchored proteins, including surface antigen 3 (SAG3

197 ositol-specific phospholipase C that removed GPI-anchored proteins increased CD11b-specific binding o

198 activated exocytosis of vesicles containing GPI-anchored proteins, increasing membrane area and phag

199 lin in cells that were deficient in specific GPI-anchored proteins, indicated that ecto-calreticulin

200 ere critical for rapid endocytosis because a GPI-anchored protein induced to misfold at the cell surf

201 cereus PI-PLC, which has strong activity on GPI-anchored proteins, inhibited bacterial escape from a

202 Here, we report that THY1, a GPI-anchored protein, inhibits epidermal YAP activity th

203 soluble protein requirements for packaging a GPI-anchored protein into ER-derived transport vesicles.

204 ells is known to incorporate Thy-1 and other GPI-anchored proteins into its membrane.

205 In order to identify the oolemmal GPI-anchored proteins involved in fertilization, egg sur

206 nstrate that a glycosylphosphatidylinositol (GPI)-anchored protein is also necessary because phosphat

207 pmentally regulated in schistosomes, and the GPI-anchored protein is localized to the outer tegument

208 s suggest that the intercellular transfer of GPI-anchored proteins is a regulated process, and may ha

209 to generate chemically defined analogues of GPI-anchored proteins is an important step toward elucid

210 The loss of certain GPI-anchored proteins is hypothesized to provide the mut

211 n hyphal morphogenesis and the expression of GPI-anchored proteins is made possible by an interesting

212 In fungi, the final destination of many GPI-anchored proteins is their outermost compartment, th

213 ammalian prion protein (PrP), a cell surface GPI-anchored protein, is a particularly noteworthy examp

214 Prion (PrP), a GPI-anchored protein, is infamous for being the only nor

215 Notch signalling through surface cleavage of GPI-anchored proteins, is targeted by Prdx4 oxidative ac

216 everal surface glycosylphosphatidylinositol (GPI)-anchored proteins, like the major surface antigen S

217 s (At4g26690 and At5g49270) encode predicted GPI-anchored proteins likely to be associated with lipid

218 ses/LORELEI-like GLYCOLPHOSPHATIDYLINOSITOL (GPI)-ANCHORED PROTEINS (LLG) complexes, or by leucine-ri

219 MDS1), and the glycosylphosphatidylinositol (GPI)-anchored protein LLG1 as regulators of mekk1-mkk1/2

220 sting of two CrRLK1Ls LET1, LET2/MDS1, and a GPI-anchored protein LLG1 that regulates the activation

221 n nature, many glycosylphosphatidylinositol (GPI)-anchored proteins localize in the lipid rafts.

222 luble membrane fractions have suggested that GPI-anchored proteins may be associated with glycosphing

223 t secretion and intracellular degradation of GPI-anchored proteins may occur in the same genetic back

224 ion of cholesterol-dependent nanoclusters of GPI-anchored proteins mediated by membrane-adjacent dyna

225 We found that GPI-anchored proteins mostly localized to the ER in p24d

226 st, were four members of the IgLON family of GPI-anchored proteins (Ntm, OBCAM/Opcml, Negr1, Lsamp).

227 When RBC that were deficient (GPI)-anchored protein, obtained from five patients, with

228 a variety of glycosyl-phosphatidylinositol (GPI)-anchored proteins occur extracellularly, but the mo

229 Ly6G is a glycosylphosphatidylinositol (GPI)-anchored protein of unknown function that is common

230 GPIHBP1, a GPI-anchored protein of capillary endothelial cells, bin

231 ass spectrometry demonstrated that the major GPI-anchored proteins of T. brucei procyclic forms have

232 erocomplexes of CrRLK1L receptor kinases and GPI-anchored proteins of the LRE and LLG family.

233 inds to phosphatidylcholine (PC) and cleaves GPI-anchored proteins off eukaryotic plasma membranes.

234 deficiency of glycosyl phosphatidylinositol (GPI)-anchored proteins on blood cells from patients with

235 We show that ART2.2 is expressed as a GPI-anchored protein on the surface of mature T cells.

236 Absence of GPI-anchored proteins on erythrocytes is responsible for

237 w cytometry was used to assess expression of GPI-anchored proteins on granulocytes.

238 ates of the GPI pathway but fails to display GPI-anchored proteins on its surface membrane.

239 To elucidate how BtPI-PLC searches for GPI-anchored proteins on the membrane surface, we measur

240 t of lpd-3 and knockdown of KIAA1109 reduced GPI-anchored proteins on the surface of cells, suggestin

241 ature of other glycosylphosphatidylinositol (GPI)-anchored proteins or representative cell surface pr

242 ect displacement of the membrane anchor of a GPI-anchored protein or pro-protein causing release of t

243 Glycosylphosphatidylinositol (GPI)-anchored proteins participate in many cell surface

244 Glycosylphophatidylinositol (GPI)-anchored proteins play important roles in many biol

245 ngs provide strong evidence that one or more GPI-anchored proteins play an important role in beta-sec

246 GPI-anchored proteins play vital roles in signal transdu

247 obtained physical evidence for cross-linked GPI-anchored protein, Qa-2, binding to a transmembrane p

248 When aggregates of the GPI-anchored protein, Qa-2, were scanned across plasma m

249 pha-toxin, a pore-forming toxin that targets GPI-anchored protein receptors on the surface of mammali

250 e that alpha toxin, like aerolysin, binds to GPI-anchored protein receptors.

251 predicted protective modifier that encodes a GPI-anchored protein responsible for neuron/glial intera

252 t, suggesting that it is bound to a separate GPI-anchored protein(s) at the surface of the cells.

253 The cell-surface GPI-anchored protein(s) involved in Abeta biogenesis may

254 A mutant CHO cell line (gpi85), which lacks GPI-anchored proteins, secreted lower levels of Abeta40,

255 analysis of maturing DCs, we identified the GPI-anchored protein semaphorin 7A (Sema7A) as being hig

256 Glycosylphosphatidylinositol (GPI)-anchored proteins serve as receptors for aerolysin;

257 toxin B-subunit and between antibody-labeled GPI-anchored proteins, showing these raft markers are in

258 sitol moieties present on both free GPIs and GPI-anchored proteins shows the presence of a diacylglyc

259 ngth influences the diffusion coefficient of GPI-anchored proteins: smaller proteins diffuse faster t

260 A diverse group of GPI-anchored protein structures are ubiquitously express

261 that binds to glycosyl phosphatidylinositol (GPI)-anchored proteins, such as Thy-1, on sensitive targ

262 own to bind to glycosylphosphatidylinositol (GPI)-anchored proteins, such as Thy-1.

263 ants showed strongly reduced accumulation of GPI-anchored proteins, suggesting that they all have def

264 ted it was a glycosyl phosphatidyl inositol (GPI)-anchored protein that had a cleavable COOH-terminal

265 D59) is a cell surface glycophosphoinositol (GPI)-anchored protein that prevents complement membrane

266 or (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored protein that promotes tissue remodeling, t

267 e-associated [glycosyl-phosphatidylinositol (GPI)-anchored] protein that we call DRAGON.

268 CD14, a GPI-anchored protein that associates with TLR4 in mediat

269 phila acetylcholinesterase (AChE) as a model GPI-anchored protein that can be manipulated in vivo wit

270 homologous with Vanin-1, a recently reported GPI-anchored protein that is expressed on perivascular t

271 These results suggest that cd59b encodes a GPI-anchored protein that is functionally active as a me

272 Thy-1 (CD90) is a small GPI-anchored protein that is particularly abundant on th

273 mechanism of peptide perception in plants by GPI-anchored proteins that act together with a phylogene

274 o aerolysin (a bacterial toxin that binds to GPI-anchored proteins), they were equally susceptible to

275 hich encodes a glycosylphosphatidylinositol (GPI)-anchored protein thought to be involved in ascospor

276 lease of transferase is specific, as another GPI-anchored protein, Thy-1 is not released.

277 romoter of the glycosylphosphatidylinositol (GPI)-anchored protein Thy1 have been widely used to exam

278 Cleavage of GP2, a GPI-anchored protein tightly associated with activation

279 uch as CD14, a glycosylphosphatidylinositol (GPI)-anchored protein to the plasma membrane important f

280 es not express glycosylphosphatidylinositol (GPI)-anchored proteins to eliminate potential competitio

281 etic analysis of GPI anchor biosynthesis and GPI-anchored protein trafficking in T. gondii and other

282 ata suggest a potential therapeutic role for GPI-anchored protein transfer for severe PNH.

283 eir physico-chemical properties, to regulate GPI-anchored protein transport and maintain homeostasis

284 ses, which uniquely involve aggregation of a GPI-anchored protein, versus other protein misfolding di

285 Cell surface expression of major GPI-anchored proteins was diminished in GPI-deficient T.

286 iginating from a mutant cell line that lacks GPI-anchored proteins was not neutralized.

287 The plasma membrane localization of GPI-anchored proteins was restored in the p24delta3delta

288 te of transport of carboxypeptidase Y, a non-GPI-anchored protein, was observed.

289 To examine the role of GPI-anchored proteins, we specifically removed these pro

290 ptor-like kinases and the SOS5 extracellular GPI-anchored protein were shown previously to act on a p

291 Several lymphocyte cell lines lacking GPI-anchored proteins were also shown to be less sensiti

292 As expected, GPI-anchored proteins were decreased on PB cells of PNH

293 The GPI-anchored proteins were found to highly accumulate in

294 The azide-labeled GPIs and GPI-anchored proteins were then tagged with biotin on li

295 as an axonal glycosyl-phosphatidyl-inositol (GPI)-anchored protein, whereas the MAG receptor has rema

296 major surface glycosyl phosphatidylinositol (GPI)-anchored protein which is rich in Glu-Pro repeats.

297 that ox-PAPC may initially bind to a 37-kDa GPI-anchored protein, which interacts with TLR4 to induc

298 ce predicted a glycosylphosphatidylinositol (GPI)-anchored protein with a signal peptide, a transmemb

299 sistent with the preferential association of GPI-anchored proteins with glycosphingolipid-enriched do

300 The strategy can be used to label GPI-anchored proteins with various tags for biological s