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1 erences in participant age, PSA results, and Gleason score).
2 erum samples of prostate cancer positive for Gleason score.
3 tion method, publication calendar period and Gleason score.
4 rimers used, publication calendar period and Gleason score.
5 in three different groups according to their Gleason score.
6 nds observed for lymph node invasion and the Gleason score.
7 of early recurrence, independently of their Gleason score.
8 in EN2 levels according to genetic status or Gleason score.
9 were down-regulated in tumors with a higher Gleason score.
10 ntly affected by pathologic lesion volume or Gleason score.
11 maller lesions and is not affected by lesion Gleason score.
12 r confirmation is required with biopsies and Gleason score.
13 ely correlated with increased prostate tumor Gleason score.
14 ding T-stage, prostate-specific antigen, and Gleason score.
15 increase or decrease in primary or secondary Gleason score.
16 ated with the PSA level and original primary Gleason score.
17 for ERG staining was associated with higher Gleason score.
18 expression is directly correlated with high Gleason scores.
19 the clinical stages of prostate cancers and Gleason scores.
20 between the image features and ROI-specific Gleason scores.
21 tures correlate moderately with ROI-specific Gleason scores.
22 n system compared with clinical criteria and Gleason scores.
23 rmality is benign or malignant and to assign Gleason scores.
24 een found to correlate negatively with tumor Gleason scores.
25 poor outcome in patients with low or average Gleason scores.
26 s and the association between ADCs and tumor Gleason scores.
27 compared to normal tissue or tumors with low Gleason scores.
28 in the mutation rate was observed at higher Gleason scores.
30 an ADCs were inversely associated with tumor Gleason scores (1.10, 0.98, 0.87, and 0.75 for Gleason s
31 ically registered whole-mount histology with Gleason scoring, (11)C-choline, and ADC data (obtained a
32 teria for AS were tumor stage (all cohorts), Gleason score (12 cohorts), prostate-specific antigen (P
33 italier de l'Universite de Montreal) were of Gleason score 3 + 3 = 6 (51%) while most of the specimen
34 ed on detection of low-risk prostate cancer (Gleason score 3 + 3 or low-volume 3 + 4) and the biopsy
36 rsitaire de Quebec-Universite Laval) were of Gleason score 3 + 4 = 7 (51% and 52%, respectively).
39 rostate cancer (clinical stage T2a or lower; Gleason score, 3+3; index tumor </=10 mm(3)) underwent M
44 all cases (P = 0.013) and for a subset of 19 Gleason score 7 cases (P = 0.010), both of which were ad
51 with positive lymph node (PLN) count </= 2, Gleason score 7 to 10, pT3b/pT4 stage, or positive surgi
54 in the placebo group had high-grade cancer (Gleason score, 7 to 10) (relative risk, 1.17; 95% CI, 1.
55 ging (80.6% vs. 80.9%, P = 0.54), or primary Gleason score (77.9% for <=7 vs. 82.6% for >=8, P = 0.38
56 ificant high-grade and larger-volume tumors (Gleason score 8 and 9) with higher specificity than MR i
57 y include men with seminal vesicle invasion, Gleason score 8 to 10, extensive positive margins, and d
62 tly predicted metastasis within 10 years was Gleason score (8-10 vs 5-7; OR 2.14, 95% CI 1.77-2.58; p
63 e-specific antigen was 15.1 ng/mL; 53% had a Gleason score 9 to 10 cancer; 27% had cT3 to cT4 disease
64 imaging, histologically composed of a large Gleason score 9 tumor with an adjacent Gleason score 7 n
65 e, lower pretherapeutic hemoglobin, a higher Gleason score, a higher number of platelets, higher C-re
66 cases, we identify two loci associated with Gleason score, a pathological measure of disease aggress
67 edict which patients will have a high biopsy Gleason score, a standard pathology score used to grade
68 tatistically associated with a high combined Gleason score, advanced stage, and prostate-specific ant
71 thologic measure of malignancy, the surgical Gleason score, agrees better with these genomic paramete
72 Loss of this axis was associated with higher Gleason scores, an increased likelihood of metastatic an
74 ated with prostate tumor progression to high Gleason score and elevated PSA levels, and served as an
75 wn as JMJD2A) was positively correlated with Gleason score and metastasis in human prostate tumors.
77 unx2 staining was positively correlated with Gleason score and occurrence of lymph node metastases wh
80 nly slightly attenuated after adjustment for Gleason score and PSA at diagnosis (HR, 0.33; 95% CI, 0.
81 stic biopsy than it does with the diagnostic Gleason score and related measures of diagnostic histopa
82 hat includes cell type adjustments and using Gleason score and the seven-gene signature has some util
84 imens and its expression was correlated with Gleason scores and prostate-specific antigen recurrence.
85 Spearman correlation coefficients between Gleason scores and the ADC features were between -0.27 a
87 retreatment prostate-specific antigen level, Gleason score, and clinical tumor stage for FFBF, and hy
88 influence of antihormonal treatment, primary Gleason score, and contribution of PET and morphologic i
90 e variable analyses, pathologic tumor stage, Gleason score, and pre-SRT PSA were associated with BcR,
91 ostate-specific antigen (PSA) level, primary Gleason score, and prior therapy (androgen deprivation t
93 I, showed a significant correlation with the Gleason score, and the tumor SUV(max) was able to discri
94 of TMPRSS2:ERG fusions in relation to race, Gleason score, and tumor stage, combining results from G
96 of the genes were low for non-cancer and low Gleason scores, and 6/6 known prostate cancer markers we
97 had higher prostate-specific antigen values, Gleason scores, and rates of extracapsular extension and
98 levels correlated with higher pT stages and Gleason scores, as well as with androgen (AR) and estrog
102 ncer at MR imaging had a greater risk of the Gleason score being upgraded at subsequent biopsy (hazar
103 ameters, 10th percentile ADC correlated with Gleason score better than did other ADC parameters, sugg
104 ole-lesion histogram and correlated with the Gleason score by using the Spearman correlation coeffici
105 iated with prognostic factors including high Gleason score, clinical stage, prostate-specific antigen
106 s, clinically localized PCa, availability of Gleason score, data available for post-treatment PSA and
107 to the measure of prostatic malignancy, the Gleason score, derived from individual prostate biopsy t
108 imaging is significantly dependent on lesion Gleason score; detection of lesions of >/=1 cm3 is signi
111 or stage for FFBF, and hypofractionation and Gleason score for PCaSS were significant prognostic vari
112 nical parameters (prostate-specific antigen, Gleason score) for pathologic EPE prediction by using th
114 h template biopsy, one man had cancer with a Gleason score greater than 6; at 24 months, three men ha
116 between benign and malignant tissue, between Gleason score (GS) </= 3 + 3 and GS >/= 3 + 4 tumors, an
117 ears were included; 599 patients (24%) had a Gleason score (GS) </= 6, 1,387 (56%) had a GS of 7, 244
118 nts to these decision rules, on detection of Gleason score (GS) 7 or greater (GS >/=7) prostate cance
126 dy was to explore the ability of the initial Gleason score (GS) to predict the rate of detection of r
128 rent prostate-specific antigen (PSA) values, Gleason score (GS), and d'Amico risk classification.
129 hieved reasonably accurate classification of Gleason scores (GS) 6(3 + 3) vs. >/=7 and 7(3 + 4) vs. 7
130 he correlation of uptake within the gland to Gleason scores (GS) and assessment of the predictive pot
131 late biopsy results, including corresponding Gleason scores (GS), number of positive cores, and tumor
132 g (MRI) and have correlated this with grade (Gleason score; GS) and pathological staging (pT) of pros
133 n (PSA) (>0.2 ng/mL) and high-risk features (Gleason score > 7, PSA doubling time < 10 mo, or PSA > 1
134 was recommended for biopsy progression (ie, Gleason score > or = 7, or > 2 positive cores, or > 50%
135 primary endpoint definition (>/= 4 mm and/or Gleason score >/= 3+4), sensitivity, negative predictive
136 for detection of high-risk prostate cancer (Gleason score >/= 4 + 3); secondary end points focused o
137 are reclassified to a higher-risk category (Gleason score >/= 7) or who have significant increases i
139 gnosed, 571 of which were aggressive (biopsy Gleason score >/= 7, and/or clinical stage III or greate
140 %, P = 0.0381), but independent from primary Gleason score >/= 8 (92.0%) versus </= 7 (90.2%, P = 0.6
142 gnosed with high-risk cancers (>/= T3 and/or Gleason score >/= 8), postdiagnosis daily aspirin use wa
144 Clinically significant cancer was defined as Gleason score >/=4 + 3 or a maximum cancer core length 6
146 sitively related to incidence of high-grade (Gleason score >/=7) tumors (rate ratioQ5-Q1 = 3.92; 95%
148 nostic factors, such as Gleason grade 4 + 3, Gleason score >/=7, vascular infiltration, and positive
150 gnificant PCa (SPCa), which was defined as a Gleason score >= 3 + 4 (Gleason grade group 2 or higher)
151 cers and noncancers, clinically significant (Gleason score >= 7) cancers from clinically insignifican
153 TC+/AR-V7+ patients were more likely to have Gleason scores >/= 8 ( P = .05), metastatic disease at d
155 tivity for discriminating PCa between higher Gleason score (>/=7) and lower Gleason score (<7) was 0.
156 io, 1.03; 95% CI, 1.00-1.05; P = 0.037), and Gleason score (>7: hazard ratio, 2.49; 95% CI, 1.25-4.95
158 ine positive biopsy findings (size, >/=3 mm; Gleason score, >/=6) were identified in 68 patients.
159 survival benefits from treating aggressive (Gleason score, >/=7) early-stage prostate cancer are und
160 e plasminogen activator receptor (uPAR), and Gleason score in patients undergoing prostate biopsy.
163 GF-beta signaling was associated with higher Gleason scores in archived human biopsies, mirroring mur
167 ive treatment practices whereby cases with a Gleason score lower than 7 and clinical T2a stage cancer
169 sk tumor characteristics (PSA < 10 ng/mL and Gleason score < 7), and 89.2% underwent active treatment
170 ance (ie, PSA density < 0.15 ng/mL/cm(3) and Gleason score < or = 6 with no pattern > or = 4, involvi
172 intermediate-risk prostate cancer (T1 to 2a, Gleason score </= 6, and prostate-specific antigen [PSA]
173 < 0.15 ng/mL, and prostate biopsy findings (Gleason score </= 6, two or fewer cores with cancer, and
175 prostate specific antigen [PSA] </=15 ng/mL, Gleason score </=4 + 3, stage </=T2), with no previous a
176 cy was poor in small (<0.5 cc) or low-grade (Gleason score </=6) tumors, with a tendency toward overe
177 -risk disease (clinical stage </=T2a, biopsy Gleason score </=6, and prostate-specific antigen level
179 Patients with newly diagnosed LPCa with Gleason score <= 7, clinical stage T1b to T3a, and prost
181 etween higher Gleason score (>/=7) and lower Gleason score (<7) was 0.96 (95% CI, 0.93-0.98) and 0.90
183 inically low-risk prostate cancer (cT1-cT2a, Gleason score</=6 at biopsy, prostate-specific antigen [
184 ity (0.83 [reader 1] and 1.00 [reader 2] for Gleason score</=6 vs 0.82 and 0.92 for Gleason score>/=7
185 49-70 years) with localized prostate cancer (Gleason score</=7, prostate-specific antigen level #15 m
186 h low-risk prostate (clinical stage T1c/T2a; Gleason score, </=6; and prostate-specific antigen level
187 all men in the very-low-risk group) (T1-T2; Gleason score, </=6; and PSA, <10 ng/mL), and intermedia
188 of the low-risk group) (clinical stage, T1c; Gleason score, </=6; prostate-specific antigen [PSA], <1
189 prostate-specific antigen [PSA], <=15 ng/mL; Gleason score, <=3 + 4; clinical stage, <=T2c; lesion si
191 rent prostate-specific antigen (PSA) levels, Gleason scores, marital statuses and bone metastasis sta
192 significantly associated with a higher tumor Gleason score (mean ADCs of [1.21, 1.10, 0.87, and 0.69]
195 ine PET/CT positivity and initial treatment, Gleason score, National Comprehensive Cancer Network sta
196 ine PET/CT positivity and initial treatment, Gleason score, NCCN stage, PSA level, PSA doubling time,
199 nificantly higher in prostate cancers with a Gleason score of >/=3 + 4 than with a Gleason score of <
200 evel of proNGF was observed in tumors with a Gleason score of >/=8 compared with a Gleason score of 7
201 with a Gleason score of 7, and three with a Gleason score of >/=8) and five nonneoplastic prostate s
203 o of the three high-risk prognostic factors (Gleason score of >=8, presence of three or more lesions
205 .69] x 10(-3) mm(2)/sec were associated with Gleason score of 3 + 3, 3 + 4, 4 + 3, and 8 or higher, r
206 ith prostate adenocarcinoma (three patients, Gleason score of 3 + 4; and three patients, Gleason scor
207 y a majority of readers yielded tumor with a Gleason score of 3+4 or greater in 45.9% (17 of 37), wit
209 that sector to be deemed positive was set at Gleason score of 3+4 or more and/or cancer core length i
210 stage pT2a, intermediate-risk cancer with a Gleason score of 3+4) and caused 11 additional false-pos
211 Gleason score of 3 + 4; and three patients, Gleason score of 4 + 5) was performed across 23 spatiall
212 arameter to help differentiate tumors with a Gleason score of 6 from those with a Gleason score of at
213 Az values for differentiating lesions with a Gleason score of 6 from those with a Gleason score of at
216 of 18 prostate cancer samples (seven with a Gleason score of 6, eight with a Gleason score of 7, and
222 This accuracy was good in tumors with a Gleason score of 7 or higher or a Likert score of 5, wit
224 tate cancer was performed in patients with a Gleason score of 7 or less in three or fewer cores limit
225 needle biopsy, there were 220 tumors with a Gleason score of 7 to 10 among 3299 men in the dutasteri
226 even with a Gleason score of 6, eight with a Gleason score of 7, and three with a Gleason score of >/
227 ne risk factor (pathological T-stage 3 or 4, Gleason score of 7-10, positive margins, or preoperative
229 g years 3 and 4, there were 12 tumors with a Gleason score of 8 to 10 in the dutasteride group, as co
230 than 40 mug/L or PSA of 20 to 40 mug/L plus Gleason score of 8 to 10 were randomly assigned to lifel
231 tive models in discriminating cancers with a Gleason score of at least 7 among peripheral zone (PZ) l
232 ate results in discriminating cancers with a Gleason score of at least 7 among PZ lesions at 3 T in d
233 systematic biopsies; nearly 40% of men with Gleason score of at least 7 CaP are diagnosed only by ta
234 with a Gleason score of 6 from those with a Gleason score of at least 7 was assessed by using the ar
235 with a Gleason score of 6 from those with a Gleason score of at least 7 were 0.704, 0.692, 0.758, an
236 itivity of 0.95 in diagnosing cancers with a Gleason score of at least 7, and the area under the rece
239 .88 (95% CI, 0.67-1.00) for discriminating a Gleason score of greater than or equal to 3 + 4 from a G
240 detection of primary prostate cancer with a Gleason score of greater than or equal to 3 + 4 in men w
241 detection of primary prostate cancer with a Gleason score of greater than or equal to 3 + 4 in men w
242 detection of primary prostate cancer with a Gleason score of greater than or equal to 3 + 4 is cost-
245 cutoff could be established for detecting a Gleason score of greater than or equal to 4 + 3 with a s
247 ore of greater than or equal to 4 + 3 from a Gleason score of less than or equal to 3 + 4, a cutoff c
248 eason scores (1.10, 0.98, 0.87, and 0.75 for Gleason scores of 3 + 3, 3 + 4, 4 + 3, and >/= 4 + 4, re
250 scheduled to undergo prostatectomy; they had Gleason scores of 7-10 and a mean prostate-specific anti
251 y set of ten tumor/normal subject pairs with Gleason scores of 8-10 at diagnosis, coordinated analysi
252 >50% clinical prostate cancer specimens with Gleason scores of 8-9 (n=11), which is associated with p
253 alphaDG subunit inversely correlate with the Gleason scores of prostate cancers; furthermore, we show
256 ated dose or type of statin, clinical stage, Gleason score, or with prediagnosis statin use; however,
257 Nuclear expression of Kaiso correlates with Gleason score (P < 0.001) and tumor grade (P < 0.001).
260 e) analysis, tumor Likert score (P < .0001), Gleason score (P = .009), and Vh (P < .0001) significant
263 SA) at diagnosis (P for trend < .001), lower Gleason score (P for trend < .001), and less advanced tu
264 lue over standard prognostic markers such as Gleason score, pathologic tumor stage, surgical margin s
265 static progression, with variables including Gleason score, preoperative prostate-specific antigen co
266 x) was able to discriminate between low-risk Gleason score profiles and intermediate risk Gleason sco
267 Gleason score profiles and intermediate risk Gleason score profiles with a high diagnostic accuracy.
268 en (PSA) doubling time of less than 3 years, Gleason score progression, or unequivocal clinical progr
269 patients who had not had radiotherapy using Gleason score, prostate-specific antigen concentration,
271 and that its expression correlates with high Gleason score, pT and pN stages, and biochemical recurre
272 aled that FDPS is associated with increasing Gleason score, PTEN functionally deficient status, and p
273 ake in tumors was positively correlated with Gleason score (rho = 0.64; PSMA expression, rho = 0.47;
274 (Spearman rho [rho], range, -0.07 to 0.24), Gleason score (rho, range, 0.03 to 0.20), prostate-speci
275 pre-HIFU PSA level and favourable pathologic Gleason score seem to present better oncologic outcomes.
278 e, year, race, comorbidity score, PSA level, Gleason score, T stage, N stage, chemotherapy administra
280 cluded older age, comorbid conditions, lower Gleason score, tumor stage, PSA concentration, and favor
281 y associated with lower risk of biopsy-based Gleason score upgrade (hazard ratio per 1-year decrease,
283 sociated with decreased risk of biopsy-based Gleason score upgrade during AS but not with risk of def
286 ssess time to cancer progression, defined as Gleason score upgrading, prostate-specific antigen veloc
288 h tracers and corrected our calculations for Gleason scores using iterative matched-pair analyses.
289 1] and 0.61 [reader 2]) rather than when the Gleason score was >/=7 (0.73, P=.02 [reader 1]; and 0.84
290 ies were significantly lower when the lesion Gleason score was </=6 (0.44 [reader 1] and 0.61 [reader
292 tissue array samples representing a range of Gleason scores, we found that OLFM4 protein expression c
293 the Spearman rho values for correlation with Gleason score were -0.31, -0.30, -0.36, and -0.35, respe
295 from prostate cancer patients with known the Gleason score were tested showing a significant statisti
296 d marital status, lower PSA levels and lower Gleason scores were better prognostic factors in PCa.
299 d morphology is an integral component of the Gleason score which enables discrimination between prost
300 A proportion of men experience an upgrade in Gleason score while undergoing active surveillance.