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1 Gram-negative bacteremia is a common infection that resu
2 Gram-negative bacteria and their complex cell envelope,
3 Gram-negative bacteria are surrounded by an outer membra
4 Gram-negative bacteria have a cell envelope that compris
5 Gram-negative bacteria have evolved numerous pathways to
6 Gram-negative bacteria release outer membrane vesicles i
7 Gram-negative bacteria repopulated in the smokers faster
8 Gram-negative bacteria, mitochondria, and chloroplasts a
9 Gram-negative bacterial infections are a significant pub
10 Gram-negative bacterial lipoproteins are triacylated wit
11 Gram-negative bloodstream infections represent a signifi
12 Gram-negative intestinal domination was associated with
13 Gram-negative pathogens are enveloped by an outer membra
14 Gram-positive bacteria have developed secretion systems
15 Gram-scale production has been realized, paving the way
16 Gram-scale synthesis provided an acrylamide analogue, wh
17 nel to other methods of identification of 20 Gram-positive bacteria, four antimicrobial resistance ge
18 lecular methods for the identification of 20 Gram-positive pathogens and four antimicrobial resistanc
19 eptibility testing using a collection of 297 Gram-negative bacilli, including members of the order En
21 not included): Gram-positive bacteria, 58%; Gram-negative bacteria, 78%; and Candida species, 83%.
22 The MICs of CFDC were determined for 610 Gram-negative bacilli, including 302 multinational Enter
25 y known requirements for PIC targeting are a Gram-negative cell envelope and a unique cell surface an
28 inosa IMPORTANCE Pseudomonas aeruginosa is a Gram-negative bacterium frequently isolated from infecte
29 ica serovar Typhimurium (S Typhimurium) is a Gram-negative bacterium that induces cell death of macro
37 o damage caused by Listeria monocytogenes, a Gram-positive bacterium, BCV rupture by Gram-negative pa
40 ed the presence of RgNanOx homologues across Gram-negative and Gram-positive bacterial species and co
43 erophore cephalosporin with activity against Gram-negative bacterial species that are resistant to ca
45 treptogramins(2), potent antibiotics against Gram-positive bacteria that inhibit the bacterial riboso
46 -deoxyglucosone (3-DG) were assessed against Gram-positive and Gram-negative pathogenic and food spoi
47 high level in E. coli, is effective against Gram-negative clinical isolates, and has efficacy in mou
48 oglycoside antibiotics are effective against Gram-negative infections, these drugs often cause irreve
52 OMP folding is an essential process in all Gram-negative bacteria, and considering the looming cris
55 Given that ompA is highly conserved among Gram-negative pathogens, these studies not only provide
57 am stain-negative Pseudomonas aeruginosa and Gram stain-positive Staphylococcus aureus bacteria, indu
58 ed Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial pathogens as
60 Gram-negative Escherichia coli (E. coli) and Gram-positive Enterococcus durans (E. durans) and Staphy
62 ghput scRNA-seq method for Gram-negative and Gram-positive bacteria that can resolve heterogeneous tr
63 gle-cell transcriptomes of Gram-negative and Gram-positive bacteria with high purity and low bias, wi
64 cultures in patients with Gram-negative and Gram-positive bacteria, including 8/60 (13.3%) patients
65 RgNanOx homologues across Gram-negative and Gram-positive bacterial species and co-occurrence with s
67 vity extends to a range of Gram-negative and Gram-positive wound pathogens in planktonic culture and,
68 zed filters quickly killed Gram-positive and Gram-negative bacteria aerosols in vitro, with CFU reduc
69 that neutrophils recognize Gram-positive and Gram-negative bacteria by means of multiple phagosomal T
71 ctivity against the tested Gram-positive and Gram-negative bacteria, with a large zone of inhibition
74 ion and penetration of the Gram-positive and Gram-negative bacterial cell envelope, but do not ruptur
75 is of intact proteins from Gram-positive and Gram-negative bacterial colonies sampled directly on sol
76 -DG) were assessed against Gram-positive and Gram-negative pathogenic and food spoilage bacteria, bot
77 lied for Gram-positive Bacillus subtilis and Gram-negative Escherichia coli as model organisms to mon
79 ed Gram-negative Escherichia coli Symbio and Gram-positive Enterococcus faecalis Symbio or placebo fr
80 athogens and mixed infections with yeast and Gram-negative organisms from the same positive blood cul
81 tions in this study were caused by bacteria; Gram-positive bacteria were responsible for most cases.
83 with yeast cells and various strains of both Gram-positive and -negative bacteria revealed distinct b
85 degree of bactericidal activity toward both Gram stain-negative Pseudomonas aeruginosa and Gram stai
87 As 80% of prostatitis cases are caused by Gram-negative uropathogenic Escherichia coli (UPEC) or G
88 hronic inflammatory disease characterized by Gram-negative bacteria responsible for the degradation o
90 Outer membrane vesicles (OMVs) produced by Gram-negative bacteria have roles in cell-to-cell signal
92 s, a Gram-positive bacterium, BCV rupture by Gram-negative pathogens such as Shigella flexneri or Sal
96 ted using a cohort of contemporary, clinical Gram-negative bacillus isolates from 3 U.S. academic med
100 S in vitro and inhibit the growth of diverse Gram-negative bacteria, including polymyxin-resistant st
102 antimicrobial resistance phenotypes, during Gram-negative bacterial infection and will advance our u
103 his breaks the dogma that beta-lactams enter Gram-negative bacteria only by passive diffusion through
107 he proposed EAST is successfully applied for Gram-positive Bacillus subtilis and Gram-negative Escher
108 tomography-guided fine-needle aspiration for Gram stain and cultures is unnecessary in the majority o
110 ay of isoprenoid synthesis, is essential for Gram-negative bacteria, mycobacteria and apicomplexans(2
112 ics), a high-throughput scRNA-seq method for Gram-negative and Gram-positive bacteria that can resolv
113 RDT facilitated antibiotic optimization for Gram-positive BSIs but led to unnecessary escalation of
114 ificities, moderately high sensitivities for Gram-negative bacteria and Candida species, and elevated
115 ST (median, 23 vs 7.4 hours, P < .001), from Gram stain to optimal therapy (median, 11 vs 7 hours, P
117 on the biogenesis and functions of EVs from Gram-positive bacteria and identify key areas for future
118 lied to the analysis of intact proteins from Gram-positive and Gram-negative bacterial colonies sampl
119 use of ADX significantly decreased time from Gram stain to ID (median, 23 vs 2.2 hours, P < .001) and
120 y; however, there is little knowledge on how Gram-negative bacteria release their OMs into their envi
121 enMark Dx ePlex Blood Culture Identification Gram-Positive (BCID-GP) Panel is a multiplex nucleic aci
123 ts on a benzisoxazole scaffold with improved Gram-positive antibacterial activity relative to previou
127 t only in Gram-positive bacteria but also in Gram-negative C. jejuni, advancing our knowledge of the
128 ntimicrobial susceptibility testing (AST) in Gram-negative rod (GNR) bacteremia is compelling; howeve
129 the beta-barrel assembly machinery (BAM) in Gram-negative bacteria, and by the sorting and assembly
133 nhances combinatorial antigenic diversity in Gram-negative bacteria, while reducing associated fitnes
134 eptation is critical to faithful division in Gram-negative bacteria and vital to the barrier function
135 o differences in cell wall structure, EVs in Gram-positive bacteria have been disregarded for decades
140 nally, we discover aminoacyl-PGs not only in Gram-positive bacteria but also in Gram-negative C. jeju
143 prevalent cause of antibiotic resistance in Gram-negative bacteria, i.e., the deactivation of the mo
145 uring LPS transfection; however, its role in Gram-negative bacteria-mediated NLRP3 inflammasome activ
146 catechol species are important Fe sources in Gram-positive human pathogens, since PiuA functions in t
148 is an uncharacterized protein ubiquitous in Gram-negative bacteria whose gene frequently occurs in c
150 CTX-M beta-lactamases are widespread in Gram-negative bacterial pathogens and provide resistance
151 vitro infection model with heat-inactivated Gram-positive (Staphylococcus aureus) and Gram-negative
152 icrobiota assessments at all visits included Gram stain Nugent scoring and 16S rRNA gene qPCR and HiS
153 gulase-negative staphylococci not included): Gram-positive bacteria, 58%; Gram-negative bacteria, 78%
154 ority pathogens listed by the WHO, including Gram-negative bacteria in the critical priority category
156 a bacterial lysate consisting of heat-killed Gram-negative Escherichia coli Symbio and Gram-positive
157 e salt-functionalized filters quickly killed Gram-positive and Gram-negative bacteria aerosols in vit
162 S) are essential envelope components in many Gram-negative bacteria and provide intrinsic resistance
164 n resistance methyltransferase found in many Gram-positive pathogens, whereas ErmE is found in the so
167 h activity against multidrug-resistant (MDR) Gram-negative pathogens as the pipeline of antibiotics i
169 on between cell envelopes with one membrane (Gram-positive or monoderm) and those with two membranes
170 e or monoderm) and those with two membranes (Gram-negative or diderm) is a fundamental open question
172 control of Pseudomonas aeruginosa, a motile Gram-negative, opportunistic bacterial pathogen which fr
173 d bloodstream infection due to nonfermenting Gram-negative bacilli (odds ratio, 6.33; 95% CI, 1.59-25
174 lar catheter infections due to nonfermenting Gram-negative bacilli was high for the femoral insertion
175 ized arterial catheters due to nonfermenting Gram-negative bacilli were more frequently observed at t
178 nd a general blueprint for the conversion of Gram-positive-only compounds into broad-spectrum antibio
183 This study investigated the inactivation of Gram-negative Escherichia coli (E. coli) and Gram-positi
185 has been widely used to treat infections of Gram-positive bacteria including Clostridium difficile a
191 aride (LPS) resides in the outer membrane of Gram-negative bacteria where it is responsible for barri
193 We use our findings to propose a model of Gram-negative cell envelope stabilization that includes
195 re strongly associated with lower numbers of Gram-negative organisms at indoor sites (p < 0.0001).
196 rimeric porins in the outer membrane (OM) of Gram-negative bacteria are the conduits by which nutrien
202 lecular patterns including peptidoglycans of Gram-positive bacteria and lipopolysaccharides of Gram-n
204 diatric institution with a low prevalence of Gram-negative resistance, the VG RDT facilitated antibio
206 bactericidal activity extends to a range of Gram-negative and Gram-positive wound pathogens in plank
207 a potent antibiotic against a broad range of Gram-positive bacteria, but its medical applications hav
208 Pseudoalterin binds to the glycan strands of Gram positive bacterial PG and degrades the PG peptide c
209 g proteins (GBPs) assemble on the surface of Gram-negative bacteria into polyvalent signaling platfor
210 I-seq captures single-cell transcriptomes of Gram-negative and Gram-positive bacteria with high purit
212 ommonly used clinically for the treatment of Gram-positive skin and skin structure infections (SSSI),
217 ive uropathogenic Escherichia coli (UPEC) or Gram-positive Enterococcus faecalis, we used a mouse tra
220 l envelope stability(4); however, most other Gram-negative bacteria lack Lpp so it has been assumed t
221 sistance genes, and both Pan Candida and Pan Gram-Negative targets that are unique to the BCID-GP Pan
222 greement and NPA for the Pan Candida and Pan Gram-Negative targets were 92.4% and 95.7% for the forme
226 Cases were defined as 3GC-R-BSI or 3GC-R Gram-negative infection (3GC-R-GNI) (analysis 2), all ot
227 ly, our data show that neutrophils recognize Gram-positive and Gram-negative bacteria by means of mul
230 acterial assays with wild-type and resistant Gram negative bacteria carrying either single or multipl
231 ctivity against both sensitive and resistant Gram positive (using 1500 ppm) as well as sensitive and
238 tment of a wide range of multidrug resistant Gram-negative bacterial infections, by both intravenous
241 trum of activity against multidrug-resistant Gram-negative bacteria; however, breakpoints have been e
242 rtunistic and frequently multidrug-resistant Gram-negative bacterial pathogen that primarily infects
244 listin) for treatment of multidrug-resistant Gram-negative infections, many clinical laboratories are
246 ins are covalently attached to PG in several Gram-negative species, including Coxiella burnetii, Agro
247 ross prokaryotes, and in particular, several Gram-negative bacterial pathogens including Neisseria me
248 engineered to attach specifically to several Gram-negative organisms, including the human pathogens E
249 nts, initial staining of liquid media showed Gram-positive rods or cocci, including some cocci in cha
251 ng through correlation with direct staining (Gram and calcofluor white) and CSF cryptococcal antigen
253 ng antibacterial activity against the tested Gram-positive and Gram-negative bacteria, with a large z
255 he methods of surface charge modulation that Gram-negative organisms may adopt for antibiotic resista
260 resistance seems to be universal across the Gram-positive bacteria, while the type of coselected tra
261 isine A showed moderate activity against the Gram-negative bacterium Escherichia coli, but no further
262 tance in the preeminent etiologic agent, the Gram-positive bacterium Staphylococcus aureus Bacterial
263 d aggregate lipopolysaccharide (LPS) and the Gram-negative bacterium Escherichia coli However, the ph
265 teria have one pathway or the other, but the Gram-positive, facultative intracellular pathogen Lister
266 five bacterial diguanylate cyclases from the Gram-negative bacterium Salmonella Enteritidis, identify
267 re, we detected LPS-derived lipid A from the Gram-negative pathogens, Escherichia coli (Ec, m/z 1797)
268 pp, all directly interact with XPRT from the Gram-positive bacterium Bacillus subtilis and inhibit XP
269 ibe the characterization of a MINPP from the Gram-positive bacterium Bifidobacterium longum (BlMINPP)
272 omplex, which parallel recent studies in the Gram-negative intestinal pathogen Campylobacter jejuni.
276 oped a method to directly detect and map the Gram-negative bacterial virulence factor lipid A derived
279 rs induce deformation and penetration of the Gram-positive and Gram-negative bacterial cell envelope,
282 embraned cells and the derived nature of the Gram-positive envelope following multiple OM losses.
283 vironment of two live bacterial strains: the Gram-negative Escherichia coli and the Gram-positive Bac
287 pecies spanning different classes within the Gram-negative phylum Proteobacteria: Agrobacterium tumef
288 diversity and ability to form biofilms, this Gram-negative nonfermenting bacterium can persist in the
290 nt SmartProbes offer a comparative method to Gram stain for delineating gram-positive or gram-negativ
296 investigated the binding of CTRP6 to various Gram-negative bacteria as well as PRMs and enzymes of th
297 peptides when the flies were challenged with Gram-positive bacteria Micrococcus luteus In this settin
298 ow-derived macrophages (BMDMs) infected with Gram-negative bacteria such as Citrobacter rodentium, Es
300 of positive blood cultures in patients with Gram-negative and Gram-positive bacteria, including 8/60