ライフサイエンスコーパス: HA

1 HA did not alter relative abundances of non-oral genera.

2 HA negatively regulates excitatory gain onto D1(+)-MSNs

3 HAs from human IAVs exhibit "human-type" receptor specif

4 Influenza A group 1 HA stem-nanoparticles have been demonstrated to confer h

5 enantioselective against a panel of group 1 HAs and F0045(S) exhibits in vitro neutralization activi

6 to nanomolar affinity to influenza A group 1 HAs.

7 tigenically drifted clade 6B.1A 183P-5A+156K HA genes (VE 7%; 95%CI: -14 to 23%) which predominated a

8 tibody responses to cross-react with group 2 HAs.

9 he original exposure HA antigen and the 2009 HA protein affected antigenic-site immunodominance.

10 mation reactions (Cl2 + H2O + A- k-4k4HOCl + HA + Cl-) were necessary to accurately simulate Cl(2) co

11 eloped 2D perovskite (HA)(2) (GA)Pb(2) I(7) (HA=n-hexylammonium, GA=guanidinium).

12 s and disadvantages for the development of a HA-based vaccine against HPAIV.

13 Abnormal HA accumulation within blood vessel walls is associated

14 Little is known about HA head glycosylation of low-pathogenicity avian influen

15 iable NaNO(3), Ca(NO(3))(2), and humic acid (HA) concentrations were used to differentiate individual

16 Biological functions of hyaluronic acid (HA) depend on its molecular size.

17 Hyaluronic acid (HA) is a highly abundant component in the extracellular

18 se of heparan sulfate (HS), hyaluronic acid (HA), and sialic acid on human trophoblast cell lines and

19 rtantly, we also found that hyaluronic acid (HA)-decorated CP/Ad-SS-GD/RNP nanocomplexes targeting mu

20 bout how cells navigate the hyaluronic acid (HA)-rich, nanoporous ECM of the brain, a problem with fu

21 Free hydroxycinnamic acids (HAs) were mainly chlorogenic acids, with 5-caffeoylquini

22 he incidence and trend of hospital-acquired (HA) antibiotic-resistant organisms (AROs) and multidrug-

23 Additionally, human-adapted HAs gain glycosylation sites over time, although their b

24 Increasing evidence supports adding HA stability to pre-pandemic risk assessment algorithms.

25 onium ([P(4444)](+)) hydroxide with adenine (HAd) and thymine (HThy) led to hydrated salts of deproto

26 lish strong "immunological imprints" against HA stalk antigens first encountered during primary influ

27 ssion in B cells was required for nearly all HA stalk-specific IgG2c antibodies and for durable neutr

28 infection promotes inflammation via altered HA and versican production, we studied an ex vivo human

29 SPR-generatedin-frame deletion to contain an HA tag at the N terminus of the large UNC-89 isoforms.

30 To tackle this problem, we engineered an HA tag onto Cx26 or Cx30 subunits and imaged hemichannel

31 s in extension and mechanical response of an HA chain as aggrecan monomers bind and form a bottlebrus

32 results demonstrate that PGA-FLUO within an HA-CP penetration enhancer represents an effective topic

33 HV: CSD filled by the combination of DBG and HA in a high-viscosity crosslinking agent.

34 LV: CSD filled by the combination of DBG and HA in a low-viscosity crosslinking agent; group DBG/HV:

35 The H5 LPAIVs of the HA-III and HA-IV subgroups appeared in 2015 and 2017 in unusually h

36 ied into three subgroups (HA-II, HA-III, and HA-IV).

37 in, but not mRNA, was higher in AD, MCI, and HA-NCI, while mature NGF was lower.

38 Both seroprevalence and HA diversity were significantly increased in carnivores

39 effectiveness of systemically delivered anti-HA bNAbs was not dependent on antiviral neutralization,

40 ed glycosylation sites (i.e. sequons NCSV at HA 54, NHTV at HA 125, and NLSK at HA 160) identified by

41 n sites (i.e. sequons NCSV at HA 54, NHTV at HA 125, and NLSK at HA 160) identified by MTL-SGL to det

42 s NCSV at HA 54, NHTV at HA 125, and NLSK at HA 160) identified by MTL-SGL to determine antigenic cha

43 hat rats with high addiction-like behaviors (HA) exhibited a significant increase in gamma-aminobutyr

44 Paradoxically, these heterosubtypic-boosted HA stalk antibodies do not bind efficiently to the boost

45 ohorts, we showed that the induction of both HA and NA antibodies after infection is influenced by ag

46 Amino acids were decreased less by HA than did FIR.

47 interrogate synaptic mechanisms recruited by HA signaling at glutamatergic synapses in the NAc.

48 lation is the structural feature that causes HA stiffening.

49 Of these constructs, the chimeric HA (cHA) vaccine with consensus H5 as globular head and

50 ) of expanded Ab breadth elicited by a COBRA HA-based immunogen and advances efforts toward design an

51 Two candidate COBRA HA vaccines, P1 and X6, elicited antibodies with differe

52 ed HA antigens (designated V1 to V12), COBRA HA antigens, or wild-type HA antigens.

53 Furthermore, imaged Cx26/Cx30-HA triple liganded by Fab-HA showed multiple arrangement

54 ated the mechanisms by which a destabilizing HA mutation, Y17H (activation pH, 6.0), attenuates virus

55 ave suffered resistance due to destabilizing HA mutations that do not compromise replicative fitness

56 infrared radiation (FIR) and hot air drying (HA) were applied to unpolished and polished pigmented ri

57 s around the RBS will lead to more effective HA immunogens.

58 Stress-evoked HA signaling in the NAc recruits H(3) heteroreceptor sig

59 ic relatedness between the original exposure HA antigen and the 2009 HA protein affected antigenic-si

60 nization of chickens with rAPMV-3 expressing HA protein induced higher level of neutralizing antibodi

61 se results suggest that a rAPMV-3 expressing HA protein might be a better vaccine for mass-vaccinatio

62 tibodies compared to that of rNDV expressing HA protein.

63 MC021-HA can compensate for the loss of F13-HA by facilitating wrapping to produce EV and further de

64 Similar to F13-HA, MC021-HA was capable of interacting with both A33 an

65 , imaged Cx26/Cx30-HA triple liganded by Fab-HA showed multiple arrangements that can be derived from

66 FLAIR-HAs favoured recanalisation (1.21, 95% CI 1.06 to 1.38)

67 FLAIR-HAs were also associated with early recanalisation or ha

68 FLAIR-HAs were not associated with functional outcome overall

69 at proximal MCA or within DWI lesions, FLAIR-HAs beyond DWI lesions were associated with better outco

70 l or imaging outcomes with presence of FLAIR-HAs after AIS.

71 roup analyses by treatment or types of FLAIR-HAs defined by location (at proximal/distal middle cereb

72 Contrary to FLAIR-HAs at proximal MCA or within DWI lesions, FLAIR-HAs bey

73 BM group at week 4 (35.16% versus 14.00% for HA/TCP and DBBM, respectively) but less than that at wee

74 tivity, and understanding the mechanisms for HA protein cleavage and how they may differ depending on

75 ereas the opposite results were observed for HA in all samples.

76 ng the expression levels of the receptor for HA-mediated motility, RHAMM, and the HA-binding protein

77 1, 2, and 5 mM) from humic acid samples (1 g HA/L) of different redox states.

78 tabolic regulation of endothelial glycocalyx HA and its potential as a therapeutic target in diabetic

79 ire of naive T cells specific for cryptic H1-HA peptides and demonstrate that antigen processing repr

80 the influenza pandemic H1 hemagglutinin (H1-HA).

81 ll as cryptic peptides spanning the whole H1-HA sequence.

82 standard cell cultures, a destabilizing H1N1 HA stalk mutation greatly diminishes viral replication a

83 ore whether patterns of local charge of H1N1 HA can explain this discrepancy and thus further associa

84 It is possible that the H1N1 HA is under other biophysical constraints that result in

85 against a majority of the viruses in the H2 HA panel.

86 g) is occupied by high-mannose glycans in H3 HA but by complex glycans in all LPAIV HAs.

87 SP-D was not active on LPAIV but was on H3 HAs.

88 A/Singapore/GP1908/2015 H1N1 haemagglutinin (HA).

89 -binding glycoprotein is the haemagglutinin (HA), and following receptor-mediated uptake of the bound

90 Haloanisoles (HAs) are known to compromise wine quality because of the

91 ccharide hyaluronan (HA) to form covalent HC.HA complexes, thereby stabilizing an extracellular matri

92 pendent manner, providing a mechanism for HC.HA cross-linking and matrix stabilization.

93 mmunity and further elucidate the role of HC.HA complexes in inflammation and ovulation.

94 Hemagglutinin (HA) stability, or the pH at which HA is activated to cau

95 alk region of the influenza A hemagglutinin (HA) surface protein.

96 oped to quantify the absolute hemagglutinin (HA, the main influenza antigen) amount in the vaccine wi

97 topes on the surface antigens hemagglutinin (HA or H) and neuraminidase (NA or N).

98 uenza virus surface antigens, hemagglutinin (HA) (including head and stalk regions) and neuraminidase

99 ntibodies against 3 different hemagglutinin (HA) subtypes, at low prevalence, while carnivores showed

100 nza glycoproteins, especially hemagglutinin (HA).

101 ve and selective receptor for hemagglutinin (HA) protein, which is a biomarker for AIVs.

102 reactive antigens (COBRA) for hemagglutinin (HA).

103 conformational epitopes on H5 hemagglutinin (HA) from different clades that were associated with anti

104 S03 significantly enhanced H5 hemagglutinin (HA)-specific plasmablast and antibody responses compared

105 Influenza hemagglutinin (HA) glycoprotein is the primary surface antigen targeted

106 conserved region of influenza hemagglutinin (HA) stalk (or stem) has gained attention as a potent tar

107 ody-antigen complex involving hemagglutinin (HA), the primary immunogenic antigen of the influenza vi

108 asonal influenza carrying key hemagglutinin (HA) head region glycosylation sites can be removed from

109 ion, we tested for effects on hemagglutinin (HA) binding and neuraminidase (NA) cleavage.

110 pared to what is available on hemagglutinin (HA) responses, despite growing evidence that NA immunity

111 tants containing A(H1N1)pdm09 hemagglutinin (HA) and neuraminidase (NA) genes with genetic combinatio

112 the receptor-binding protein, hemagglutinin (HA), which recognizes sialic-acid-containing glycans on

113 ic analysis revealed that the hemagglutinin (HA) gene of H5 isolates belonged to the Eurasian lineage

114 epitope substitutions in the hemagglutinin (HA) of each challenge virus that impacted protection, re

115 or-binding specificity by the hemagglutinin (HA) surface antigen.

116 responses, principally on the hemagglutinin (HA) viral surface protein.

117 1 (IFNAR1) by utilizing viral hemagglutinin (HA).

118 activation of influenza virus hemagglutinin (HA) glycoprotein via cleavage by host cell proteases is

119 against the influenza A virus hemagglutinin (HA) have been well studied, very limited information is

120 igated four influenza B virus hemagglutinin (HA) head specific, hemagglutination inhibition-inactive

121 enic drift of influenza virus hemagglutinin (HA) is enabled by facile evolvability.

122 IAV) through interaction with hemagglutinin (HA) head region high-mannose glycan(s).

123 Hemagglutinins (HAs) from human influenza viruses adapt to bind alpha2-6

124 Therefore, we used a hemoadsorber (HA) to remove pro-inflammatory cytokines.

125 n a highly dynamic state that exposes hidden HA head domain features.

126 (MCI), or no cognitive impairment with high (HA-NCI) and low (LA-NCI) brain Abeta from the Religious

127 ter rHA vaccination may be due to its higher HA content.

128 ctive properties compared to the shorter HMM-HA.

129 44 protein-protein interactions, whereas HMM-HA promotes them.

130 elation was detected between circulating HMW-HA and apnoea-hypopnoea-index (r = - 0.195, p = 0.043),

131 Our aim was to evaluate circulating HMW-HA and HYAL-1 in OSA.

132 Under inflammation or hypoxia, HMW-HA is degraded by hyaluronidases, such as HYAL-1 resulti

133 However, HA antigenic site B, which has become immunodominant in

134 Hyaluronan (HA) is one of the most prevalent glycosaminoglycans of t

135 Hyaluronan (HA), a ubiquitous glycosaminoglycan of the lung extracel

136 r its main structural component, hyaluronan (HA).

137 nges such as the accumulation of hyaluronan (HA) and versican in the subepithelial space in promoting

138 s formed from the polysaccharide hyaluronan (HA) and the proteoglycan aggrecan contribute to cartilag

139 nsferred onto the polysaccharide hyaluronan (HA) to form covalent HC.HA complexes, thereby stabilizin

140 mic stress abnormally synthesize hyaluronan (HA) in intracellular compartments.

141 fied PARP1 as an interacting partner for IAV HA through mass spectrometry analysis.

142 RP1), plays a critical role in mediating IAV HA-induced degradation of IFNAR1.

143 IAV HAs from different virus strains showed consistently red

144 ts of murine proteases facilitate H3 and IBV HA cleavages.

145 age, classified into three subgroups (HA-II, HA-III, and HA-IV).

146 calation of oxycodone self-administration in HA rats but not in LA rats.

147 tran-based fluorescence assay and changes in HA receptor expression using immunofluorescent microscop

148 Our results implicate localized charge in HA interactions with host cells, and highlight how deep

149 lective sorption of oxygen-rich compounds in HA fractions to mineral oxides is a decisive factor for

150 ur results demonstrated that the decrease in HA concentration elicited a reduction in the total lengt

151 tations and variations in N-glycosylation in HA caused antigenic variations in H1N1 IAVs and that the

152 Intra-CeA levels of N/OFQ were lower in HA rats than in LA rats.

153 The plasminogen activator tPA was lower in HA-NCI while neuroserpin, the CNS tPA inhibitor, was hig

154 ike peptide, normalized GABA transmission in HA rats.

155 nstrated that RSV infection led to increased HA accumulation compared with control mice, which also c

156 her study the process of fusion, we incubate HA for different times at pH 5.0 and directly image stru

157 mor necrosis factor alpha (TNFalpha) induced HA-mediated monocyte adhesion and AoSMC migration, where

158 ess how egg-adaptive substitutions influence HA immunogenicity.

159 ntibodies induced by the 2009 H1N1 influenza HA protein were affected by the viral strain the individ

160 r (DFP) is directly drawn by pultrusion into HA fibers that display high aspect ratios, ranging from

161 Intracellular HA-DAT colocalized with VPS35, a subunit of the retromer

162 Furthermore, the abnormal intracellular HA was also observed in peripheral blood monocytes deriv

163 hyperglycemia also accumulate intracellular HA and that heparin inhibits the HA accumulation.

164 However, unlike the related leukocyte HA receptor CD44, which uses ERM and ankyrin motifs with

165 ls as key players in the accumulation of LMW-HA in the tumor microenvironment and cancer-related infl

166 in H3 HA but by complex glycans in all LPAIV HAs.

167 Although MC021-HA expression did not fully restore plaque size, vMC021L

168 Similar to F13-HA, MC021-HA was capable of interacting with both A33 and B5.

169 These results suggest that MC021-HA can compensate for the loss of F13-HA by facilitating

170 idative and enzymatic hyaluronidase-mediated HA breakdown.

171 les (VLPs) expressing one of the 12 modified HA antigens (designated V1 to V12), COBRA HA antigens, o

172 analysis, received HD-MAPs delivering 15 mug HA or uncoated HD-MAPs applied to the forearm.

173 , 5, 2.5, or 0 mug of HA to the FA or 15 mug HA to the upper arm (UA), or IM injection of QIV.

174 hanism through which cells engage nanoporous HA matrix and may represent an important molecular targe

175 ith low FA, low MDI and disruption of normal HA transmural profile on micro-CT were associated with m

176 altered extracellular matrix accumulation of HA occurs following RSV infection and may contribute to

177 the evolutionary history and adaptability of HA as a transmitter.

178 HA-elicited mAbs exhibited a wide breadth of HA recognition, ranging from narrowly reactive to broadl

179 showed a higher prevalence and diversity of HA-specific antibody responses against 11 different subt

180 for immunological memory in the dynamics of HA and NA antibody responses.

181 hyaluronan fragmentation, and effacement of HA from the vessel wall of small pulmonary arteries.

182 ing from past antigens or better exposure of HA epitopes.

183 The fragmentation of HA by myeloid cells was mediated by the membrane-bound e

184 ide linkage between carboxylic acid group of HA and amine group of dopamine.

185 provide evidence that the immunodominance of HA stems in part from its abundance on the viral surface

186 ning to probe the local fitness landscape of HA antigenic site B in six different human H3N2 strains

187 only recently described the localization of HA in the olfactory system of the cuttlefish Sepia offic

188 lected platform facilities the modulation of HA levels independently of matrix rigidity.

189 ivering doses of 15, 10, 5, 2.5, or 0 mug of HA to the FA or 15 mug HA to the upper arm (UA), or IM i

190 equence coverages upon UV photoactivation of HA and of the HA.antibody complex indicates the eliminat

191 sively along the putative epitope regions of HA in the presence of the antibody.

192 layed an important role in the regulation of HA-degrading activity of Hyal2-expressing myeloid cells,

193 RE pupil, clear lens and tubular remnant of HA containing blood cells in its lumen freely rotating i

194 istic picture of how flexibility and size of HA and aggrecan lead to the brush architecture and mecha

195 t on a potential obstacle for the success of HA-stalk-targeting universal influenza vaccines-viral es

196 The (re)synthesis of HA is dependent on the availability of its sugar substra

197 The use of HA in advanced stages of peri-implantitis resulted in a

198 Sorption of HAs to DAX-8 was less selective and caused only slight c

199 By contrast, poorly adapted avian-origin HAs contain predominately complex-type glycans, which ha

200 Other HA traits necessary for pandemic potential are poorly un

201 Overall, HA destabilization decreased virulence in mice by boosti

202 P1 HA-elicited mAbs exhibited a wide breadth of HA recognit

203 Interestingly, we identified a P1 HA-elicited mAb (1F8) exhibiting broad hemagglutination

204 , to evaluate the Ab response elicited by P1 HA at increased resolution, a panel of P1 HA-specific B

205 ively, the functional characterization of P1 HA-elicited mAbs sheds further insights into the underly

206 P1 HA at increased resolution, a panel of P1 HA-specific B cell hybridomas was generated following im

207 cture of a recently developed 2D perovskite (HA)(2) (GA)Pb(2) I(7) (HA=n-hexylammonium, GA=guanidiniu

208 la (pre-/probiotics for Cluster 3 [17%], pHF-HA for Cluster 4 [7%], eHF/soya for Cluster 5 [4%]).

209 ly hydrolysed with hypoallergenic label [pHF-HA], extensively hydrolysed [eHF], soya) and solid food

210 nthetic hydroxyapatite/tricalcium phosphate (HA/TCP) particles were inserted into one of the sinus ca

211 med a forward genetic screening of PIN2:PIN1-HA;pin2 Arabidopsis (Arabidopsis thaliana) plants, which

212 The odds ratio for postdischarge HA-VTE associated with COVID-19 compared with 2019 was 1

213 n conferred resistance to some of the potent HA stalk broadly neutralizing monoclonal antibodies (bNA

214 The crystal structure of H1/PR8 HA in complex with our best hit compound F0045(S) confir

215 sed to screen H1/Puerto Rico/8/1934 (H1/PR8) HA trimer against ~72,000 compounds.

216 estigated the hypothesis that SOD3 preserves HA homeostasis by inhibiting oxidative and enzymatic hya

217 onths, using all data, patients who received HA-WBRT plus memantine reported less fatigue (P = .04),

218 Clinical trials comparing recombinant HA vaccine (rHA) and cell-derived inactivated influenza

219 , they are present in all tested recombinant HAs and whole viruses and can be specifically targeted f

220 We additionally generated an RFX6(HA) reporter allele by gene targeting in wild-type H9 ce

221 Plasma/serum HA level is becoming recognized as a biomarker of endoth

222 ent redox properties of dissolved and sorbed HA fractions.

223 exchange capacities of dissolved and sorbed HA fractions.

224 vidence of preferential sorption of specific HA fractions, primarily tannin-like compounds, to Al(2)O

225 fluenza viruses containing both a stabilized HA and alpha-2,6 receptor binding in tandem pose greater

226 ter selection of a variant with a stabilized HA.

227 09-2016, gamma-clade viruses had less stable HA proteins (activation pH 5.5-5.9) than pandemic clade

228 el for human adaptation, a relatively stable HA protein (pH 5.5-5.6) was necessary for efficient repl

229 an lineage, classified into three subgroups (HA-II, HA-III, and HA-IV).

230 derived tumor cells, as well as in synthetic HA matrix and organotypic brain slices.

231 Our results indicate that HA forms an adsorbed surface layer, but its charge, thic

232 Our findings suggest that HA and FIR may have a significant effect on the internal

233 of human bnAbs FI6v3 and CR9114 against the HA stem.

234 all molecules have been reported against the HA.

235 tor for HA-mediated motility, RHAMM, and the HA-binding protein TNF-stimulated gene 6 protein (TSG6).

236 protection by rAPMV3 and rNDV expressing the HA protein against HPAIV challenge in chickens.

237 s study, we generated rAPMV-3 expressing the HA protein of H5N1 HPAIV using reverse genetics and eval

238 However, the HA proteases involved in the activation of many viral st

239 he last group consists of those sites in the HA core, with no change in net charge and that evolve ve

240 Accumulation of mutations in the HA gene has resulted in several phylogenetic clades, whi

241 d that three amino acid substitutions in the HA head domain contributed to the resistance.

242 g site of the HA protein, as they are in the HA protein of mammalian influenza A viruses.

243 Amino acid positions in the HA protein that may be involved in the antigenic variati

244 ulum containing an A388V polymorphism in the HA stalk (45% wild type and 55% mutant).

245 S) confirmed that it binds to pockets in the HA stem similar to bnAbs FI6v3 and CR9114, cyclic peptid

246 the highly conserved fusion machinery in the HA stem, we synthesized a fluorescence-polarization prob

247 btype owing to structural differences in the HA stem.

248 indifferent, the mean labeled surface in the HA/TCP group was significantly greater than those in the

249 tracellular HA and that heparin inhibits the HA accumulation.

250 the bound virus by endocytosis(1), it is the HA that mediates fusion of the virus envelope with the m

251 es and amino acids located at the tip of the HA molecule enhanced the elicitation of these broadly re

252 We determined the crystal structure of the HA protein of the avian H7N9 influenza virus in complex

253 ocated near the receptor binding site of the HA protein, as they are in the HA protein of mammalian i

254 A better understanding of the HA structures around the RBS will lead to more effective

255 The H5 LPAIVs of the HA-III and HA-IV subgroups appeared in 2015 and 2017 in

256 ges upon UV photoactivation of HA and of the HA.antibody complex indicates the elimination of some se

257 positions of high-mannose glycosites on the HA of human H1N1 and H3N2 strains are conserved.

258 Here we show that immune pressure on the HA stalk can lead to expansion of escape mutant viruses

259 matic hypermutation (SHM) and recognized the HA stem region of multiple influenza virus subtypes.

260 reactive influenza vaccines that target the HA protein have suffered resistance due to destabilizing

261 al of a monoclonal antibody that targets the HA stalk (CR6261) in a H1N1pdm09 healthy volunteer human

262 dy-binding sites, and within or close to the HA receptor binding site.

263 formational rearrangements through which the HA mediates membrane fusion.

264 ment and molecular structure analysis of the HAs were performed for LPAIV strains in comparison to se

265 These HA mutations have also been found in field isolates in 2

266 s to humans and poultry, the impact of these HA substitutions, either individually or in combination,

267 This HA tag results in normal organization of body wall muscl

268 Representative strains of three HA subgroups replicated restrictively in specific-pathog

269 dies to NA lags behind that of antibodies to HA.

270 ticle mobility when nanosilver is applied to HA-rich agricultural soils with modest ionic strength.

271 lled adult patients with brain metastases to HA-WBRT plus memantine or WBRT plus memantine.

272 ual primordial common bulb, branching off to HA and CRA with CRAO occurring first.

273 As such, we compared the antibody profile to HA and NA in two naturally infected human cohorts in Auc

274 Seroconversion to HA was more frequent in those <20 years old (yo) for inf

275 All vaccines boosted titers to HA with egg-adaptive substitutions, suggesting boosting

276 ositive mAbs elicited by the P1 or wild-type HA Ags.

277 V1 to V12), COBRA HA antigens, or wild-type HA antigens.

278 Comparatively, several wild-type HA vaccines elicited antibodies against a majority of th

279 epitope supports a model in which uncleaved HA trimers exist on the surface of infected cells in a h

280 ndogenous protein is fused with a double (V5-HA) epitope tag at the C-terminus.

281 The V5-HA tag allows unequivocal detection of RanBP9 both by IH

282 plasmablast response to the highly variable HA head region.

283 While the NAc expresses various HA receptor subtypes, mechanisms by which HA modulates N

284 nts of EV similar to those produced by vF13L-HA, suggesting that MC021 retained some of the functiona

285 Our results implicate vHMM-HA in anti-aging mechanisms and suggest the potential ap

286 d suggest the potential applications of vHMM-HA for enhancing cellular stress resistance.

287 nclear if exceptional polymer length of vHMM-HA is important for longevity.

288 Here, we show that vHMM-HA (>6.1 MDa) has superior cytoprotective properties com

289 We find that vHMM-HA suppresses CD44 protein-protein interactions, whereas

290 romotes IAV replication by controlling viral HA-induced degradation of host type I IFN receptor.

291 n did not fully restore plaque size, vMC021L-HA produced amounts of EV similar to those produced by v

292 t-cause analysis of hospital-associated VTE (HA-VTE).

293 ntation of homeostatic high molecular weight HA promoted HPASMC proliferation in vitro, whereas pharm

294 gglutinin (HA) stability, or the pH at which HA is activated to cause membrane fusion, has been assoc

295 us HA receptor subtypes, mechanisms by which HA modulates NAc circuit dynamics are undefined.

296 While HA was previously suggested to be present in the cephalo

297 obusta coffee beans were roasted either with HA or SHS in a fluidized bed roaster at 210-250 degrees

298 macroporosities of osteons were filled with HA/TCP residual particles, whereas the newly formed bone

299 UtA preconstricted with phenylephrine, with HA-UtA showing increased sensitivity.

300 anoleptic quality of wines contaminated with HAs, by reducing the cork taint and enhancing their over