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1 HCHs exist as different conformers that can be converted
2 ility of 2D hybridhalide perovskites, the 2D HCH crystal offers a promising approach for designing co
5 lake contained an estimated 98.8 tonnes of a-HCH and 13.2 tonnes of y-HCH; by 2016, only 2.7% and 7.9
12 a-TBECH, beta-TBCO, DPTE), BDE-17, and alpha-HCH ((13)C-labeled and nonlabeled) was evident in soils
13 and and -1.7 +/- 0.2 per thousand) and alpha-HCH (epsilon(c) = -1.0 +/- 0.2 per thousand and -1.6 +/-
15 .0 +/- 0.1 per thousand for (-) and (+)alpha-HCH, respectively, while those for the beta-, gamma-, de
17 ctors (epsilon(c)) of (+)alpha- and (-)alpha-HCH were increased from cells suspensions (-6.3 +/- 0.1
22 pha-HCH enantiomers was higher for (+) alpha-HCH (epsilon(c) = -2.4 +/- 0.8 per thousand and -3.3 +/-
25 E), OCPs: alpha-hexachlorocyclohexane (alpha-HCH) and (13)C(6)-alpha-HCH, trans-chlordane (TC), and (
27 inity for alpha-hexachlorocyclohexane (alpha-HCH) concentrations and enantiomer fractions (EFs) in th
28 ations of alpha-hexachlorocyclohexane (alpha-HCH) in zooplankton from June (1.18, 95% CI: 1.06-1.29 n
29 nts, like alpha-hexachlorocyclohexane (alpha-HCH), showed isotope fractionation and enantiomer fracti
31 ncentrations up to 0.75 +/- 0.06 ng/L. alpha-HCH pond enrichment may lead to substantial concentratio
32 that some of these compounds (lindane, alpha-HCH, and endosulfans) are well on their way to being vir
33 ctic returned higher concentrations of alpha-HCH and HCB through both the atmospheric (polar easterli
34 nantiomer and isotope fractionation of alpha-HCH are two independent processes and both are affected
36 s deposition results in an increase of alpha-HCH concentration from 0.07 +/- 0.02 ng/L (old ice) to 0
38 ght), alongside a higher percentage of alpha-HCH enantiomeric fractions closer to racemic ranges, ind
41 ncentration and isotope composition of alpha-HCH from the Quaternary and Tertiary aquifers were analy
42 over 70% of measured concentrations of alpha-HCH in air and ocean water within factors of 3 and 5, re
43 ion to characterize the degradation of alpha-HCH in the areas downstream of a former disposal and pro
44 ult in a significant redistribution of alpha-HCH in the water column, this process could have a signi
46 CH) ratios and enantiomer fractions of alpha-HCH indicated that a single water mass was sampled throu
48 hexane (HCH) as well as enantiomers of alpha-HCH using two aerobic bacterial strains: Sphingobium ind
51 higher surface water concentrations of alpha-HCH within 3-4 weeks with about 60% of bioconcentration
52 estigate the fate of HCH, particularly alpha-HCH in tree trunks using multielement compound-specific
53 thawing at the bottom of ponds permit alpha-HCH rich seawater (~0.88 ng/L) to replenish pond water,
54 beta-HCH is declining more slowly than alpha-HCH due to its higher persistence, and we hypothesize th
55 xperiment (no feeding) suggesting that alpha-HCH concentration in C. hyperboreus is maintained throug
57 he microbial fractionation between the alpha-HCH enantiomers was quantified by the Rayleigh equation
58 vosphingobium sp., was detected in the alpha-HCH-treated rhizosphere soil, supporting the potential f
59 m the Amundsen Gulf and measured their alpha-HCH concentrations, enantiomeric compositions, and bioac
60 0.8 per thousand) in comparison to (-) alpha-HCH (epsilon(c) = -0.7 +/- 0.2 per thousand and -1.0 +/-
62 tions, diffusion-limited turnover ((-)-alpha-HCH), substrate dissolution (beta-HCH), and potentially
63 oped and their degradation, along with alpha-HCH ((13)C-labeled and nonlabeled) was enantioselective.
68 roles of Dehalobacter as chlorobenzene- and HCH -respiring bacteria and demonstrates that sequential
72 pump due to settling of particle-associated HCHs are estimated; the removal fluxes are within a fact
73 en with confirmed pneumococcal meningitis at HCH and acute respiratory infection (ARI) trends using M
74 of SOD and GRd on the associations between B-HCH and the risk of NHD tumors (percent mediated = 33 an
75 CI: 1.03, 3.09), B-hexachlorocyclohexane (B-HCH) (HR 1.70; 95% CI: 1.09, 2.64), and hexachlorobenzen
78 ucted to investigate the transformation of B-HCH in soil-plant systems by compound specific isotope a
80 owed that the d(13)C and d(37)Cl values of B-HCH in the soil of the planted control remained stable,
81 and then facilitated the transformation of B-HCH in the wheat, which may have implications for the de
83 terium sp., and others was detected in the B-HCH-treated bulk and rhizosphere soil, potentially suppo
84 as shown that wheat is unable to transform B-HCH when growing in hydroponic culture or garden soil.
88 d OR (AOR) = 1.27; 95% CI: 1.01, 1.59]; beta-HCH was the only significant predictor in the population
90 Plasma concentrations of BDE-153 and beta-HCH did not significantly change over time, whereas conc
91 ed data on concentrations of alpha- and beta-HCH in the atmosphere and oceans, including spatial and
94 oncentrations of p,p'-DDT, p,p'-DDE and beta-HCH were not associated with diabetes or prediabetes.
97 tested in a competitive binding assay, beta-HCH did not displace 17beta-[3H]estradiol from the ER ev
99 ((-)-alpha-HCH), substrate dissolution (beta-HCH), and potentially competing reactions catalyzed by c
101 The initial 3-day treatment with either beta-HCH or o,p'-DDT doubled the relative dry weight of the u
102 eight (BW) and 104 +/- 4.4 mg/kg BW for beta-HCH and o,p'-DDT, respectively, compared to 49 +/- 1.9 m
103 reased concentrations of p,p'-DDE, HCB, beta-HCH, dicofol, and PCBs (congeners -138, -153, and -180)
104 s (POPs: PCBs, OH-PCBs, p, p'-DDE, HCB, beta-HCH, oxychlordane, BDE-47, and 153) in relation to chang
105 p'-DDT) and beta-hexachlorocyclohexane (beta-HCH) act as weak estrogens, producing uterotrophic respo
106 e compound, beta-hexachlorocyclohexane (beta-HCH), exerts estrogen-like effects in human breast cance
107 m levels of beta-hexachlorocyclohexane (beta-HCH), p,p -DDE, dichlorodiphenyltrichloroethane (p,p -DD
109 g show that during periods of lipolysis beta-HCH can be released in quantities sufficient to stimulat
110 Moreover, the delta(37)Cl values of beta-HCH also increased in the tree trunks compared to those
111 ific Northwest, serum concentrations of beta-HCH and mirex were positively associated with endometrio
112 he delta(13)C and delta(37)Cl values of beta-HCH remained stable in soil and wheat, revealing no tran
114 and dry weights showed that fasting of beta-HCH-loaded animals also increased water imbibition in th
116 with the exception that cell heights of beta-HCH-loaded, fed animals were slightly higher (P < 0.05)
119 ment with beta-HCH; this indicates that beta-HCH nether activates the ER, nor is it converted intrace
120 ata are consistent with the notion that beta-HCH stimulation of cell proliferation and gene expressio
124 eta-estradiol but not by treatment with beta-HCH; this indicates that beta-HCH nether activates the E
125 A substitution of the putative metal-binding HCH C-terminal tripeptide (thought to be required for tr
126 d suggests that specific uptake processes by HCH-degrading microorganisms might modulate the observab
128 that concentrations of many POPs (PCBs, DDT, HCHs, endosulfan) have declined significantly over the p
129 hlorination of (+)-alpha-, gamma-, and delta-HCH catalyzed by LinA2 was subject to substantial C and
131 exane (HCH), alpha-, beta-, gamma- and delta-HCH insecticides, modulated the kinetics of the GABAA re
132 amplitude of GABA-induced current, and delta-HCH strongly enhanced it in the alpha 1 beta 2 gamma 2s,
133 mineralization also convert beta- and delta-HCH to a variety of mainly hydroxylated metabolites.
134 to reactions with alpha-, gamma-, and delta-HCH, both LinA enzymes converted epsilon-HCH to a mixtur
135 alpha-, (+)-alpha-, beta-, gamma-, and delta-HCH, through changes of their C and H isotope compositio
136 ly, while those for the beta-, gamma-, delta-HCH isomers were -29.0 +/- 0.3 per thousand, -29.5 +/- 0
138 lta-HCH, both LinA enzymes converted epsilon-HCH to a mixture of 1,2,4-, 1,2,3-, and 1,3,5-trichlorob
139 o minor components of technical HCH, epsilon-HCH, and heptachlorocyclohexane (HeCH), and we present d
141 gnificantly increases the amount of ferritin HCH messages and dramatically shifts the balance toward
145 oral trend was observed for alpha- and gamma-HCH concentrations, which are decreasing in both the atm
146 screpancies observed for alpha-HCH and gamma-HCH in PUF disk versus SIP disk are attributed to lack o
148 ggest that hexachlorobenzene (HCB) and gamma-HCH were depositing from air to water whereas heavier OC
151 pe enrichment factors (epsilon(c)) for gamma-HCH (epsilon(c) = -1.5 +/- 0.1 per thousand and -1.7 +/-
152 and they ranged from about 4 years for gamma-HCH at Chicago to about 60 years for PCB-52 at Chicago.
153 decreasing relationship was found for gamma-HCH concentrations with increasing delta(15)N at Terneuz
157 e cohort, gamma-hexachlorocyclohexane (gamma-HCH) was the only POP with a significant positive associ
159 olved in the initial steps of lindane (gamma-HCH) biotransformation, was cloned and overexpressed in
160 yclohexane (HCH) mixtures and Lindane (gamma-HCH) have been produced in Bitterfeld-Wolfen, Germany, f
161 ciated with the dehydrochlorination of gamma-HCH (lindane) by two variants of the lindane dehydrochlo
163 azard Ratios estimated corresponded to gamma-HCH (3.97) and Sigma-DDT (4.39) detected in muscle sampl
164 [per 1-SD increase in log-transformed gamma-HCH: adjusted OR (AOR) = 1.27; 95% CI: 1.01, 1.59]; beta
165 ereoisomers (alpha-, beta-, delta- and gamma-HCHs) from a sample collection based on worldwide manufa
167 T, dieldrin, endrin, endosulfan, HBCDD, HCB, HCHs, heptachlor, hexabromobiphenyl, mirex, PBDEs, PCBs,
168 define a novel structural Helix-Clasp-Helix (HCH) nucleotide binding motif and show ASCC1 sequence-sp
169 of gamma- and alpha- hexachlorocyclohexane (HCH) as well as enantiomers of alpha-HCH using two aerob
170 PCB, endosulfan, and hexachlorocyclohexane (HCH) concentrations in air are decreasing at most sites.
171 phosphate (TCEP) and hexachlorocyclohexane (HCH) isomers were selected as examples of complex hetero
172 oncentrations of beta-hexachlorocyclohexane (HCH) (third vs. lowest quartile: OR = 1.7; 95% CI: 1.0,
173 ta, gamma-, and delta-Hexachlorocyclohexane (HCH), the four major isomers of technical HCH, are susce
175 ding the enzyme gamma-hexachlorocyclohexane (HCH) dehydrochlorinase (LinA2), involved in the initial
176 constant alpha/gamma-hexachlorocyclohexane (HCH) ratios and enantiomer fractions of alpha-HCH indica
177 to all the isomers of hexachlorocyclohexane (HCH) and to pentachlorocyclohexane (PCCH) but did not re
179 t the four isomers of hexachlorocyclohexane (HCH), alpha-, beta-, gamma- and delta-HCH insecticides,
183 rt of the year in the hexachlorocyclohexane (HCH) enriched surface water and for part of the year at
184 ime trend of a- and y-hexachlorocyclohexane (HCH) isomers in Lake Superior water was followed from 19
185 and alpha- and gamma-hexachlorocyclohexane (HCHs), and the sites of interest were Lakes Erie, Michig
186 rce identification of hexachlorocyclohexane (HCHs), we provide a data set of carbon, hydrogen, and ch
187 on rates of 12 gamma-hexachlorocyclohexanes (HCH)-spiked soils boosted from 40% without LMWOAs to a m
188 a on the 1,2,3,4,5,6-hexachlorocyclohexanes (HCHs) have been analyzed by Abraham's linear free energy
189 odecanes (HBCDs) and hexachlorocyclohexanes (HCHs) are polyhalogenated hydrocarbons with similar ster
190 orobenzene (HCB) and hexachlorocyclohexanes (HCHs) has been studied in the North Atlantic and Arctic
191 nuation processes of hexachlorocyclohexanes (HCHs), an important class of persistent organic pollutan
192 he concentrations of hexachlorocyclohexanes (HCHs), hexachlorobenzene (HCB), and 26 polychlorinated b
193 he highly persistent hexachlorocyclohexanes (HCHs) continues to be a threat for humans and the enviro
195 erved residues from CTD and the His-Cys-His (HCH) motif from the N-terminal segment of the neighborin
196 ening (LCS) in Health Care for the Homeless (HCH) settings, but little is known about whether the imp
198 g and sequence of the heavy chain homologue (HCH) of Drosophila melanogaster ferritin subunit have be
199 en aged <5 years at Harare Central Hospital (HCH) pre-PCV13 (January 2010-June 2012) and post-PCV13 (
200 t human skeletal diseases hypochondroplasia (HCH), achondroplasia (ACH) and thanatophoric dysplasia (
201 g/L to the detection limit of the individual HCH isomers (0.01 mug/L) after one year of operation.
202 sformation of hexachlorocyclohexane isomers (HCHs) within tree trunks could have a significant impact
203 nt organochlorine (OC) insecticides lindane (HCH) and dieldrin (HEOD) to the development of neurodege
211 bioscreen for the in situ biodegradation of HCH and its intermediates is demonstrated at a contamina
212 through the bioscreen, the concentration of HCH in the groundwater decreased from 600 mug/L to the d
213 ng decrease in atmospheric concentrations of HCH is consistent with the estimated atmospheric deposit
215 nt paper reports the differential effects of HCH isomers of the GABA-induced chloride currents in thr
216 o the muck (consisting nearly exclusively of HCH) revealed that masking isotope effects caused by the
218 dy was conducted to characterize the fate of HCH in trees over an annual growth period using compound
219 ite was conducted to investigate the fate of HCH, particularly alpha-HCH in tree trunks using multiel
222 served for alpha, beta, and gamma isomers of HCH, trans- and cis-chlordane, oxychlordane, or SigmaCHB
223 However, the transformation mechanisms of HCH in trunks particularly in growth rings are not yet w
224 ving a cycle of uptake and metabolization of HCH and refeed during littering to soil catalyzing their
226 contribute to the overall toxic potential of HCH contaminations and may constitute serious, yet unkno
227 ends reflect global sources and recycling of HCH, ongoing emissions from old stockpiles for PCBs, and
228 egradation and cometabolic transformation of HCH isomers, such processes occur over time scales of de
229 stration of the stimulated transformation of HCH to intermediates in a full scale anaerobic in situ b
231 higher delta(13)C and delta(37)Cl values of HCH of host soil samples compared to the muck (consistin
232 le growth ring section, delta(13)C values of HCH were only marginally higher or comparable to those i
233 spp. suggests that aerobic biodegradation of HCHs can be monitored in situ by compound-specific stabl
237 enantiomeric carbon isotope fractionation of HCHs with Sphingobium spp. suggests that aerobic biodegr
238 ints facilitate the source identification of HCHs at the regional scale and can be used to assess tra
244 findings suggest that the transformation of HCHs in trunks could bias quantitative phytoscreening ap
250 , during the rainy season, Lindane and Sigma-HCH in muscle and lung samples from Paso de Ovejas (995.
254 e (HCH), the four major isomers of technical HCH, are susceptible to biotic transformations, whereby
255 olation of two minor components of technical HCH, epsilon-HCH, and heptachlorocyclohexane (HeCH), and
256 ration regime, it is conclusively shown that HCH removal is the result of the biological degradation
257 experiment was conducted to characterize the HCH transformation during wheat growth using compound-sp
259 e 2D copper chloride (CuCl(6)) layers of the HCH crystal undergo Jahn-Teller distortion and subsequen
260 Cu interacts in a 1:1 stoichiometry with the HCH motif with an affinity, KD, of approximately 10(-14)
265 ater and for part of the year at depth where HCH undergoes significant microbial degradation resultin
270 study was to determine the content of DDT, y-HCH and PCB residues in popular species (Boletus badius,
272 longer than those reported in air, and for y-HCH, they were longer in water than those reported in la
275 ed 98.8 tonnes of a-HCH and 13.2 tonnes of y-HCH; by 2016, only 2.7% and 7.9% of 1986 quantities rema