ライフサイエンスコーパス: IFG

1 IFG (100 to 125 mg/dl) or insulin resistance (by homeost

2 IFG based on ADA criteria has better sensitivity than th

3 IFG based on WHO criteria and IGT predict diabetes progr

4 IFG correlated with RT specifically on salient non-targe

5 IFG effects on GCase stability and substrate levels were

6 IFG inhibits GCase with K(i) approximately 30 nM for wil

7 IFG treatment did not alter the GS and GC accumulation s

8 14% combined IGT/IFG, 9% IGT alone, and 18% IFG alone.

9 For CVD, only the 1997 IFG definition yielded significantly greater odds of CVD

10 1.0 to 3.0, p = 0.048), whereas for the 1997 IFG definition, the OR for CHD in women was 2.2 (95% CI

11 For the 2003 IFG definition, the OR for CHD among women was 1.7 (95%

12 o 1.31], women: 1.30 [95% CI: 1.10 to 1.54]; IFG 100: men: 1.23 [95% CI: 1.06 to 1.42], women: 1.16 [

13 Overall, 12.5% had diabetes and 7.8% IFG.

14 In 8 publications with information about IFG (100 to 125 mg/dl) (IFG 100), estimates of RR ranged

15 In 18 publications with information about IFG (110 to 125 mg/dl) (IFG 110), estimates of RR ranged

16 nts free of CVD, categorized by the 1997 ADA IFG definition (fasting plasma glucose 110 to 125 mg/dl;

17 ADA-IFG (4870/11 199 [43.5%), IEC-HbA(1c) (1005 [9.0%]), and

18 Although IFG is viewed as increasing CHD risk, this association i

19 e correlation with IFG-LINS (p = 0.0003) and IFG-MCING (p = 0.001) rsFC.

20 tional connectivity between the amygdala and IFG, OFC, and vmPFC.

21 ation use or fasting glucose>/=126 mg/dL and IFG as fasting glucose 100-125 mg/dL.

22 ith reference to models of dmPFC, dlPFC, and IFG functioning.

23 The incidence of DM and IFG was 1.18% (76,297) and 13.15% (847,737), respectivel

24 competition in MTG, left angular gyrus, and IFG.

25 the combination of both pre-hypertension and IFG also was associated with a cancer risk in men.

26 d influences from right TPJ to right IPS and IFG (inferior frontal gyrus).

27 arietal regions, including IPS, FEF, MFG and IFG, in addition to regions in visual cortex.

28 and right OCC, ventral occipitotemporal, and IFG regions was examined using event-related magnetoence

29 mpact of pre-hypertension on cancer risk and IFG, and their combined effects on the cancer risk.

30 archical organization of the pre-SMA-STN and IFG-STN pathways, since interruption of pre-SMA function

31 ism of branched-chain amino acids in T2D and IFG.

32 We conclude that left TPJ and IFG form a sensory-driven network that integrates contex

33 ions, we applied cTBS over the left anterior IFG (aIFG) or posterior IFG (pIFG) to test the anatomic

34 between IFG and incident DM and also between IFG and incident CV events.

35 s was used to assess the association between IFG and incident DM and also between IFG and incident CV

36 The associations between IFG, incident type 2 diabetes mellitus (T2DM), and cardi

37 and glucose disposal did not differ between IFG and NFG subjects, implying hepatic and extrahepatic

38 lity correlated negatively with rsFC between IFG and target regions (p = 0.0002), due to negative cor

39 d not find group differences in rsFC between IFG and target regions.

40 ity between the right amygdala and bilateral IFG, OFC, vmPFC, anterior cingulate cortex, and frontopo

41 hat the TD group had greater mPFC, bilateral IFG, and left superior temporal pole activity than the A

42 Both IFG and IGT are risk factors for type 2 diabetes, and ri

43 lin secretion was markedly decreased in both IFG and IGT, whereas second-phase insulin secretion was

44 In women, both IFG definitions were associated with increased CHD risk,

45 lung and spleen involvement was enhanced by IFG treatment.

46 nk between cerebral correlates of cognitive (IFG) and emotional ("fear network") processing during sy

47 Five studies combined IFG and IGT, yielding a fixed-effects summary estimate o

48 tal gyrus and dorsomedial prefrontal cortex (IFG, dmPFC).

49 y estimates for men and women were detected (IFG 110: men: 1.17 [95% CI: 1.05 to 1.31], women: 1.30 [

50 and widely used screening test in detecting IFG/IGT or NODAT, fructosamine may be a more accurate di

51 rom a 64-contact grid overlying more distant IFG sites.

52 th information about IFG (100 to 125 mg/dl) (IFG 100), estimates of RR ranged from 0.87 to 1.40.

53 th information about IFG (110 to 125 mg/dl) (IFG 110), estimates of RR ranged from 0.65 to 2.50.

54 plasma glucose >=7.8 mmol/L [>=140 mg/dL]); IFG based on American Diabetes Association (ADA) criteri

55 ) criteria (FPG >=5.5 mmol/L [>=100 mg/dL]); IFG based on WHO criteria (FPG >=6.1 mmol/L [>=110 mg/dL

56 Dysregulatory IFG dynamics were associated with weaker reciprocal exci

57 was not affected by empagliflozin in either IFG or NFG.

58 interruption of pre-SMA function can enhance IFG-STN connectivity and improve control over inappropri

59 regions relevant to cognitive control (esp. IFG/AI and the dorsal anterior cingulate cortex) were st

60 tion at baseline and follow-up examinations; IFG was defined as no T2DM and fasting glucose 100 to 12

61 e was the strongest predictive biomarker for IFG after glucose (odds ratio [OR] 1.65 [95% CI 1.39-1.9

62 g odds ratio and 95% confidence interval for IFG based on a fully adjusted model: isoleucine 2.29 (1.

63 fies girls who are at greater risk of future IFG and T2DM.

64 und, and notably, the stability of the GCase-IFG complex is pH sensitive.

65 ith development of impaired fasting glucose (IFG) after atenolol treatment.

66 n in subjects with impaired fasting glucose (IFG) and compare the results to impaired glucose toleran

67 tolerance test as impaired fasting glucose (IFG) and high HbA(1c) are also used to characterise risk

68 se associated with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) from published

69 ypertension and an impaired fasting glucose (IFG) and their combined effects on the cancer risk.

70 the development of impaired fasting glucose (IFG) and type 2 diabetes (T2DM) at age 18-19 y could pro

71 n in subjects with impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT).

72 ve of diabetes and impaired fasting glucose (IFG) in a large HBV-infected multiethnic cohort.

73 with diabetes and impaired fasting glucose (IFG) in Fukuoka, Japanese subjects (n = 1108) and age-,

74 Impaired fasting glucose (IFG) is more prevalent in men and impaired glucose toler

75 entified as either impaired fasting glucose (IFG) or impaired glucose tolerance (IGT).

76 determine whether impaired fasting glucose (IFG) predicts cardiovascular disease (CVD) events.

77 of NODAT, IGT, and impaired fasting glucose (IFG) was based on World Health Organization guidelines.

78 y assessed whether impaired fasting glucose (IFG), insulin resistance, and waist-to-hip ratio (WHR) h

79 ptomatic diabetes, impaired fasting glucose (IFG), or impaired glucose tolerance (IGT), potentially r

80 7 with predonation impaired fasting glucose (IFG).

81 iovascular risk of impaired fasting glucose (IFG).

82 he pathogenesis of impaired fasting glucose (IFG).

83 n in subjects with impaired fasting glucose (IFG).

84 e participants had impaired fasting glucose (IFG; i.e., 100-125 mg/dL FBG) at first visit.

85 2 individuals with impaired fasting glucose [IFG], and 1,897 control subjects) from TwinsUK.

86 ted history of DM; impaired fasting glucose [IFG]: FPG 5.6-6.9 mmol/L and no self-reported history of

87 he bilateral anterior interior frontal gyri (IFG), left posterior IFG, SMG, and posterior cingulate c

88 vity, with the right inferior frontal gyrus (IFG) a critical region for executive function.

89 to the left, while the infero-frontal gyrus (IFG) activation was to the right.

90 icate that the right inferior frontal gyrus (IFG) and both left and right insula were more activated

91 ed rsFC between left inferior frontal gyrus (IFG) and clusters in the left insula (LINS), lentiform n

92 d network, including inferior frontal gyrus (IFG) and inferior parietal cortex (IPC).

93 ive responses in the inferior frontal gyrus (IFG) and IPL (supramarginal) regions revealed differenti

94 rly between the left inferior frontal gyrus (IFG) and left subcortical regions (including the amygdal

95 yrus (MTG), and left inferior frontal gyrus (IFG) and of semantic competition in MTG, left angular gy

96 ontal cortex (DLPFC)/inferior frontal gyrus (IFG) and posterior cingulate cortex (PCC)/precuneus, ran

97 onal symmetry of the inferior frontal gyrus (IFG) and superior temporal gyrus (STG), the sensory and

98 rain areas including inferior frontal gyrus (IFG) and temporo-parietal junction (TPJ) were employed i

99 g network, the right inferior frontal gyrus (IFG) and the primary motor cortex (M1), using electocort

100 ) which includes the inferior frontal gyrus (IFG) and the somotosensory related cortex (SRC).

101 tal cortex (IPC) and inferior frontal gyrus (IFG) are jointly activated by duration and numerosity di

102 We focused on the inferior frontal gyrus (IFG) as our ROI, as recent studies have demonstrated bot

103 that activity within inferior frontal gyrus (IFG) correlated with offer quality, while activity in th

104 ivation at the right inferior frontal gyrus (IFG) during both tasks.

105 cortex (dlPFC), and inferior frontal gyrus (IFG) have all been implicated in resolving decision conf

106 (cTBS) over the left inferior frontal gyrus (IFG) in healthy volunteers, then used functional MRI to

107 nterior or posterior inferior frontal gyrus (IFG) in post-stroke patients with left temporo-parietal

108 cortex (OFC) and the inferior frontal gyrus (IFG) in subjects performing this task.

109 The inferior frontal gyrus (IFG) is a key cortical hub in the circuits of emotion an

110 tectonically diverse inferior frontal gyrus (IFG) of humans is known to be critically involved in a w

111 irror neurons in the inferior frontal gyrus (IFG) of humans, we used a repetition suppression paradig

112 area located in the inferior frontal gyrus (IFG) of the human brain, has been identified as one of s

113 ested that the right inferior frontal gyrus (IFG) plays a critical role in manual response inhibition

114 d feedback from left inferior frontal gyrus (IFG) region to the left occipital (OCC) region.

115 n the portion of the inferior frontal gyrus (IFG) specific to the ventral attention network (VAN).

116 rments in a DPFC and inferior frontal gyrus (IFG) system may be important in suicide attempt behavior

117 r area (pre-SMA) and inferior frontal gyrus (IFG) to the subthalamic nucleus (STN) are thought to sup

118 paired when the left inferior frontal gyrus (IFG) was driven at beta (18.7 Hz) compared to stimulatio

119 vmPFC and the right inferior frontal gyrus (IFG) was reduced when listening to excerpts with alterat

120 s-fcMRI)] with right inferior frontal gyrus (IFG), an anterior component of the ventral network.

121 ory cortex, the left inferior frontal gyrus (IFG), and the bilateral superior temporal gyrus (STG).

122 erior cingulate, the inferior frontal gyrus (IFG), and ventral and lateral temporal lobes bilaterally

123 networks [bilateral inferior frontal gyrus (IFG), bilateral medial prefrontal cortex (mPFC), and bil

124 The inferior frontal gyrus (IFG), orbitofrontal cortex (OFC), and ventromedial PFC (

125 Inferior frontal gyrus (IFG), ventral premotor cortex (PMv) and inferior parieta

126 ignatures within the inferior frontal gyrus (IFG), which our prior work has linked to impaired feedba

127 unction in the right inferior frontal gyrus (IFG)-one node in a corticothalamic inhibitory control (I

128 + > CS-) in the left inferior frontal gyrus (IFG).

129 guage regions in the inferior frontal gyrus (IFG).

130 guage area, the left inferior frontal gyrus (IFG).

131 l junction (TPJ) and inferior frontal gyrus (IFG).

132 tal gyrus (MFG), and inferior frontal gyrus (IFG).

133 es, 840 (12.7%) had T2DM and 940 (13.8%) had IFG at the baseline examination.

134 Forty (48%) recipients had IFG/IGT or NODAT.

135 Having IFG was not independently associated with an increased s

136 onic features as cortical areas in the human IFG, suggesting structural homology.

137 d is evidence of mirror neurons in the human IFG.

138 cts in insulin/insulin-like growth factor I (IFG-I) intracellular signaling processes.

139 considered the gold standard in identifying IFG/IGT or NODAT.

140 Assessment-Insulin Resistance in identifying IFG/IGT were between 0.81 and 0.85.

141 cose metabolism: 10% NODAT, 14% combined IGT/IFG, 9% IGT alone, and 18% IFG alone.

142 In IFG subjects, the defect in beta-cell glucose sensitivit

143 lucose disposal remained lower (P < 0.01) in IFG than in NFG subjects.

144 ower (P < 0.05) and EGP higher (P < 0.05) in IFG than in NFG subjects.

145 Unlike these regions, however, activity in IFG was not modulated by reductions in the relative valu

146 te distinct defects in beta-cell function in IFG and IGT.

147 eased (P < 0.05) rates of gluconeogenesis in IFG.

148 tance contribute to fasting hyperglycemia in IFG with the former being due at least in part to impair

149 ctivity and protein levels were increased in IFG-treated mice.

150 ted portal insulin concentrations present in IFG subjects after an overnight fast (approximately 80 p

151 insulin concentrations typically present in IFG subjects within 30 min of eating, extrahepatic (but

152 strength of quality and quantity signals in IFG and IPS, respectively.

153 isposition) index increased significantly in IFG, but not in subjects with normal glucose tolerance.

154 vs. 5.91+/-11 mg/g, P=0.29) were similar in IFG and normal glucose donors.

155 EGP was comparably suppressed in IFG and NFG groups during prandial insulin infusion, ind

156 Isofagomine (IFG) is an acid beta-glucosidase (GCase) active site inh

157 h the pharmacological chaperone isofagomine (IFG) at pH 7.5.

158 , we report that the iminosugar isofagomine (IFG), an active-site inhibitor, increases GlcCerase acti

159 erformed with mice treated with isofagomine (IFG), a pharmacologic chaperone for GCase.

160 I 1.3-2.5]) and less likely to have isolated IFG (0.5 [0.3-0.7]) adjusted for ethnicity, age, waist,

161 intervention groups: tDCS(anodal) over left IFG, IPC, or sham.

162 only when tDCS(anodal) was applied over left IFG.

163 revealed increased connectivity of the left IFG and additional major hubs overlapping with the langu

164 n this system, particularly between the left IFG and left pallidum, putamen, and insular cortex, is a

165 Functional connectivity between the left IFG and the right IFG and right inferior parietal lobule

166 s of the functional connectivity of the left IFG and used graph theory to study its local functional

167 d with reduced neural activation in the left IFG during speech production.

168 Significant activation in the left IFG in conjunction with other cortical and subcortical b

169 ng-state functional connectivity of the left IFG in participants with BD and in those at increased ge

170 In BD, the left IFG was functionally dysconnected from a network of regi

171 n beta frequency for stimulation of the left IFG, demonstrating an intimate causal relationship betwe

172 , a sustained oscillatory "echo" in the left IFG, which outlasted the stimulation period by approxima

173 al network involving connections of the left IFG.

174 dorsal anterior cingulate cortex and to left IFG and dorsolateral prefrontal cortex.

175 ta indicate that there is significantly less IFG, lower insulin levels, and insulin resistance, but h

176 nnections within and between the three major IFG subgyri: the pars orbitalis, pars triangularis, and

177 arietal attentional network, the IPS and MFG/IFG appear to be most heavily involved in attentive cue

178 The right middle/inferior frontal gyrus (MFG/IFG), which is included in the FPCN, showed greater conn

179 left intraparietal sulcus (IPS) and left MFG/IFG.

180 e DAN, as well as the left IPL and right MFG/IFG of the VAN.

181 ted with increased CHD risk, whereas neither IFG definition identified men at increased short-term ri

182 Nevertheless, IFG was activated only by unexpected shifts of attention

183 en avenues to primary prevention of obesity, IFG, and T2DM in children.

184 The majority (57.8%) of IFG donors had reverted to normal fasting glucose at a m

185 Administration of IFG (30 mg/kg/day) to the mice homozygous for GCase muta

186 e were 5 incident cases of T2DM, 37 cases of IFG, and 597 noncases.

187 an Diabetes Association (ADA) definitions of IFG to predict CVD.

188 change in body mass index and development of IFG and T2DM together were assessed.

189 sible pre-teen predictors for development of IFG, T2DM, and changes in body mass index at age 18-19 y

190 notype data available for the development of IFG.

191 lanine hydroxylase (PAH) with development of IFG.

192 The effect of IFG on GCase function was investigated in GCase mutant f

193 60) AA genotype had the highest incidence of IFG (P for trend=0.0003).

194 (95% CI: 10%, 58%, p = 0.003) higher odds of IFG, respectively.

195 0001), WHR (p < 0.0001), and the presence of IFG (p = 0.04), but not BMI (p = 0.24), were independent

196 rmal fasting glucose, a higher proportion of IFG donors had developed DM (15.56% vs. 2.2%, P=0.06).

197 g evidence has shown the functional roles of IFG, PMv and IPL in action understanding.

198 r individuals with the pre-diabetes state of IFG do not exhibit abnormal proximal thoracic distensibi

199 Most trials of treatment of IFG or IGT found no effects on all-cause or cardiovascul

200 trials consistently found that treatment of IFG or IGT was associated with delayed progression to di

201 Treatment of IFG or IGT was associated with delayed progression to di

202 volves not only M1 but also pars opercularis IFG, PMv and IPL, each of which plays a critical role in

203 ng action execution, and in pars opercularis IFG/PMv and M1 during action observation.

204 regions were present in the pars opercularis IFG/PMv, primary motor cortex (M1), IPL/supramarginal gy

205 The combined prevalence of diabetes or IFG was highest among blacks (36.7%) and those either bo

206 h above-median HOMA-IR, above-median WHR, or IFG had a higher LV mass-to-volume ratio (p < 0.05 for a

207 interior frontal gyri (IFG), left posterior IFG, SMG, and posterior cingulate cortices (PCC).

208 er the left anterior IFG (aIFG) or posterior IFG (pIFG) to test the anatomic specificity of the effec

209 Perturbation of the posterior IFG selectively delayed phonological decisions and decre

210 ngs suggest that the right ventral posterior IFG may play a more general role in response inhibition

211 showed that the bilateral ventral posterior IFG, anterior insula, inferior frontal junction (IFJ), m

212 Women with preconception IFG or DM had higher risk of adverse pregnancy outcomes,

213 x total caloric intake interaction predicted IFG and T2DM at age 18-19 y.

214 Assessment-Insulin Resistance in predicting IFG/IGT or NODAT were assessed using the area under the

215 hin the prefrontal-central networks (i.e., r-IFG/M1 and/or r-preSMA/M1) is realized in rapid, periodi

216 ctivation of right inferior frontal gyrus (r-IFG) and right presupplementary motor area (r-preSMA) is

217 group-level differences were not replicated, IFG-LINS rsFC was negatively correlated with a person-le

218 tivity in the beta frequency band in a right IFG/basal ganglia network, with downstream effects on M1

219 Furthermore, cingulate and right IFG volume increases were more pronounced in the MAA tha

220 aneous bilinguals between the left and right IFG, as well as between the inferior frontal gyrus and b

221 connectivity relative to controls from right IFG to dorsal anterior cingulate cortex and to left IFG

222 ne-induced change in connectivity from right IFG to dorsolateral prefrontal cortex was proportional t

223 For each patient, there was a greater right IFG response in the beta frequency band ( approximately

224 dren used a network that was primarily right IFG and bilateral pSTS, suggesting reduced use of social

225 level-dependent (BOLD) response in the right IFG (F1,78 = 14.87) and thalamus (F1,78 = 14.97) (P < .0

226 udy 2, greater IC-BOLD response in the right IFG (t23 = -2.49; beta = -0.47; P = .02), and weaker cor

227 nectivity between the left IFG and the right IFG and right inferior parietal lobule was also signific

228 propose that specialized areas in the right IFG and the left and right insula are multisensory opera

229 Our results show that TMS of the right IFG impairs categorical duration discrimination, whereas

230 These results indicate that the right IFG is specifically involved at the categorical decision

231 In addition, the right IFG response occurred 100-250 ms after the stop signal,

232 xetine increased connectivity from the right IFG to the dorsal anterior cingulate.

233 unctional connectivity seeded from the right IFG to the dorsolateral prefrontal cortex (DLPFC) and an

234 y in functional brain areas within the right IFG, supplemented by a whole-brain, exploratory analysis

235 tasks, with a congruency effect in the right IFG.

236 a decrease in beta-cell glucose sensitivity; IFG subjects, but not IGT subjects, had decreased beta-c

237 In conclusion, this T2D-IFG biomarker study has surveyed the broadest panel of n

238 001) compared with subjects not having T2DM (IFG plus normal fasting glucose).

239 Pre-teen IFG, insulin resistance (and insulin), and rapidly incre

240 ippocampal inhibition of amygdala, thalamus, IFG and dmPFC correlated with hippocampal 5-HT(1A) bindi

241 These results indicate that IFG stabilizes GCase in tissues and serum and can reduce

242 The results showed that IFG prevalence in Japanese men (15.9%) and women (7.4%)

243 To determine whether the IPC and the IFG are involved in response conflict (or facilitation)

244 ocial communication information, just as the IFG is specialized to process and integrate speech and g

245 ctions and their neural underpinnings at the IFG.

246 onstrated increased connectivity between the IFG and regions of the "fear network" (amygdalae, insula

247 p differences in seed-based rsFC between the IFG and target clusters (LINS, LENT, MCING) using multiv

248 ciprocal excitatory connectivity between the IFG and the vmPFC.

249 d coefficients of determination for both the IFG (r(2) = 0.261, p < 0.001) and the STG (r(2) = 0.142,

250 has not been well studied after changing the IFG criterion, especially in a clinical practice setting

251 ected prefrontal-limbic model comprising the IFG, vmPFC, and amygdala.

252 Lowering the threshold to define the IFG component (from 110 to 100 mg/dl) and the value of t

253 ific promoter and is also homozygous for the IFG-responsive V394L GCase.

254 Here we show that in the IFG, responses were suppressed both when an executed act

255 Specifically, neural activity in the IFG, SRC, and STS were related to cognitive empathy.

256 an association between the trajectory of the IFG and language outcomes at 4 years of age (chi(2) = 10

257 Here, we show that portions of the IFG as well as other cortical and subcortical regions in

258 Functional dysconnectivity of the IFG from regions involved in emotional regulation may re

259 ent to examine whether the activation of the IFG is dependent on the type of visuo-motor associations

260 ) and greater activity in the portion of the IFG specific to the VAN (F(1,57) = 10.311, p = .002).

261 as most pronounced in the VAN portion of the IFG, along with additional areas of the VAN and the defa

262 de causal evidence for a pivotal role of the IFG-STN pathway during action control.

263 enhanced activation and connectivity of the IFG-STN pathway.

264 solely on the functional connectivity of the IFG.

265 ipolar electrical stimuli to one site on the IFG while recording the electrical response evoked by th

266 three prefrontal-limbic regions, wherein the IFG provides evaluation of stimulus meaning, which then

267 he level of albumin excretion in 45 of these IFG donors to 45 matched controls with normal predonatio

268 Thus, IFG-LINS rsFC might constitute a risk marker, within OBP

269 eral prefrontal cortex (VLPFC) (analogous to IFG) is not, contributing instead to higher order proces

270 ling found an excitatory pathway from TPJ to IFG to FEF, suggesting that this was the pathway by whic

271 rong rs-fcMRI among themselves, not with TPJ/IFG, defining a distinct network that may retrieve/activ

272 task-related activation in the left ventral IFG, an area specifically implicated in semantic retriev

273 In 8-week IFG-treated mice, the accumulated glucosylceramide and g

274 pe 2 diabetes, and risk is even greater when IFG and IGT occur together.

275 WHO-IFG (1140 [10.2%]) and IGT (2245 [20.0%]) predicted grea

276 operties, with the combination of IGT or WHO-IFG showing the best, but still insufficient, predictabi

277 with normal fasting glucose (NFG), 845 with IFG, and 414 with diabetes, all aged 45 to 85 years and

278 R for cardiovascular disease associated with IFG and IGT is unclear.

279 line AA levels were strongly associated with IFG development.

280 Factors associated with IFG were obesity (OR, 4.13) and hypertension (OR, 3.27),

281 metabolites were found to be associated with IFG.

282 n OBP, risk score negatively correlated with IFG-LINS rsFC (p = 0.002).

283 = 0.0002), due to negative correlation with IFG-LINS (p = 0.0003) and IFG-MCING (p = 0.001) rsFC.

284 Individuals with IFG were more likely to be older and hypertensive, with

285 s of any retinopathy among participants with IFG and type 2 diabetes were 9.4% and 32.4%, respectivel

286 importance of intervention for persons with IFG to reduce their incidence of T2DM.

287 e disposal were measured in 31 subjects with IFG and 28 subjects with normal fasting glucose (NFG) af

288 Compared with NGT, subjects with IFG and IGT manifested a decrease in beta-cell glucose s

289 ransport with empagliflozin in subjects with IFG and NFG produces comparable glucosuria but lowers th

290 +/- 4 g glucosuria on day 2 in subjects with IFG and NFG, respectively, and the glucosuria was mainta

291 oncentration decreased only in subjects with IFG from 110 +/- 2 to 103 +/- 3 mg/dL (P < 0.01) after 1

292 asting glucose (NFG) and eight subjects with IFG received empagliflozin (25 mg/day) for 2 weeks.

293 ced beta-cell function only in subjects with IFG.

294 ves beta-cell function only in subjects with IFG.

295 ic stiffness was not increased in those with IFG compared with those with NFG (1.90 +/- 0.05 versus 1

296 /- 0.81 g, P < 0.0009) but not in those with IFG in comparison with NFG (145.2 +/- 1.03 versus 145.8

297 ason, an opportunity may exist in those with IFG to prevent LV hypertrophy and abnormal aortic stiffn

298 Fibroblasts treated with IFG at muM concentrations showed enhancement of WT and m

299 pared with women with normal FPG, women with IFG had higher risks of spontaneous abortion (OR 1.08; 9

300 Age 9-10 y IFG and HOMA-IR (or insulin), 10-y change in HOMA-IR (or