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1 50%), ereA (for erythromycin; 27.41%), aac-3-IV (for gentamicin; 25.38%), and the two genes cmlA (24.
3 nous tPA (tissue-type plasminogen activator; IV tPA) in acute ischemic stroke patients with prior isc
9 ve nuclear CTNNB1status in CRC stage III and IV (35% of all CRC) was not different from stage I and I
12 ) patients with advanced (ie, stages III and IV) clear cell RCC treated by nephrectomy; after exclusi
14 er patients with periodontitis Stage III and IV, Grade C respond well to the non-surgical periodontal
20 in the lung, a first event, and followed by IV lipopolysaccharide, a second event, resulted in ARDS
24 s, tooth level analysis (Class III and Class IV groups) found less residual REC and increased KT in t
25 nosed systemic lupus erythematosus and class IV lupus nephritis confirmed with biopsy and treated wit
28 0.1 viruses induced from an existing cluster IV A(H3N2)v vaccine and several seasonal inactivated inf
31 s revealed that 2 is a low-spin (S = 1/2) Co(IV) species with the unpaired electron located on the co
35 knot, dysregulation of nephrin and collagen IV, and ultrastructural changes in the trilaminar filtra
36 structural ECM genes (fibronectin, collagen IV, collagen VI, myocilin), matricellular genes (connect
39 alternative falsification test that compares IV balance or bias with the balance or bias that would h
44 c and Statistical Manual of Mental Disorders IV criteria) diagnosed after the age of 55 (LOD group) a
45 of SCN5A in the S4 voltage sensor of domain IV and stably integrated the library into HEK293T cells.
46 significant difference between the high-dose IV iron group compared with the lose-dose group in event
48 alysis for ESKD to a high-dose or a low-dose IV iron regimen, with a primary composite outcome of all
49 nzyme (ACE) and dipeptidyl peptidase IV (DPP-IV) inhibitory activities, with inhibition of ACE being
51 IIAEKTKIPAVF, IDALNENK, and VLVLDTDYK), DPP-IV-inhibitory peptides (LKALPMH, LKPTPEGDLEIL, LKGYGGVSL
52 three times a week) nonmedical use, and DSM-IV cannabis use disorder were estimated for groups with
55 r in a nonperioperative setting using either IV or intramuscular ketamine were included for analysis.
57 nteract directly with the oxido ligand in Fe(IV)-oxido complexes, which weakens the Fe=O bond and has
58 hat is drastically different from nonheme Fe(IV)-oxo synthetic model complexes; (3) The OAT step most
59 knowledge gap, we introduced a series of Fe(IV)-oxido complexes that have the same S = 2 spin ground
61 ate (high-valent diamond-core bis-mu-oxo-[Fe(IV)](2) unit) is involved in the reaction mechanism.
65 d the role of germinal cell kinase four (GCK-IV) kinases in cell death and additionally revealed thei
67 d with genome editing, we validated that GCK-IV kinase knockout improves neuronal survival, comparabl
70 ovel analogues was weaker than that of gHwTx-IV, but stronger than that of HwTx-IV, suggesting a poss
76 atients with World Health Organization grade IV glioblastomas 40 mm or less from the IHM region, loss
78 index (BMI), and tonsil size (TS), the grade IV individuals had a 4.4-fold higher risk of having CCC
81 IL5 and IL13 were highly expressed in group IV; however, groups IV and V differed in age (34 vs 14 y
82 ighly expressed in group IV; however, groups IV and V differed in age (34 vs 14 years [P < .05]).
86 nctional impact of alterations in huwentoxin-IV sequence, we produced a library of 373 point mutants
87 of gHwTx-IV, but stronger than that of HwTx-IV, suggesting a possible relationship between in vitro
89 patients with earlier Braak stages (Braak I-IV) did not show elevated tracer uptake in these regions
90 elin) and scored for cortical lesion types I-IV (mixed grey matter/white matter, intracortical, subpi
92 ration of Gynecology and Obstetrics stage IC-IV ovarian cancer and an Eastern Cooperative Oncology Gr
93 tive for Chronic Obstructive Lung Disease II-IV) who were carefully characterized (including airway m
96 or Chronic Obstructive Lung Disease stage II-IV COPD and persistent symptoms and/or serum C-reactive
97 ogical subtype, or any FIGO (1988) stage IIB-IV epithelial cancer of the ovary, fallopian tube, or pr
100 manganese ions results in high-valent Mn(III,IV)-oxide nanoparticles of the birnessite type bound to
101 (EMD) in the treatment of multiple Class III-IV Miller periodontal recession (REC) defects on mandibu
106 ck squamous cell carcinoma (HNSCC; stage III-IV according to the Union for International Cancer Contr
108 ork Heart Association functional classes III/IV (5.2%/year); 67% have survived, including 31 with hea
109 ngs indicate that locomotor muscle group III/IV afferent feedback in patients with HFrEF leads to inc
110 FrEF is excessive locomotor muscle group III/IV afferent feedback; however, this has never been inves
111 the influence of locomotor muscle group III/IV afferent inhibition via lumbar intrathecal fentanyl o
114 was lower and peak stretch higher in POP III/IV compared to non-POP and POP I/II in the main in vivo
115 nts with histologically confirmed stage IIIB-IV NSCLC who were treated with immune checkpoint blockad
116 te 153, a largely community-based phase IIIb/IV study, to evaluate the impact of 1-year fixed-duratio
117 nt is complete with a total of 19 Stage IIIC-IV OC patients in first remission after conventional the
120 ummarize the available oral and intravenous (IV) iron formulations for the treatment of IDA in CKD.
121 ave raised concerns that giving intravenous (IV) iron to patients, such as individuals receiving main
122 eted a full course of inpatient intravenous (IV) antibiotics, (2) received a partial course of IV ant
123 an concerns about the safety of intravenous (IV) iron products and erythropoiesis-stimulating agents
126 es (n=9) demonstrated typical n-shaped I(K1) IV relationship; however, following isoproterenol, max o
127 ized to 1 of 3 arginine doses: (1) 100 mg/kg IV 3 times/day (TID); (2) loading dose (200 mg/kg) then
129 double-positive cells, including Hpse+ layer IV cells targeting parvalbumin+ interneurons, leading to
131 d staining, predominantly in Cortical Layers IV and VI in 27 of the 32 cats used in the study, with f
132 ceived ROP screening examinations at a level IV neonatal intensive care unit over a 7-year period.
133 n, we defined a new severity category (level IV) with prolonged exposure to supplemental O2 (>=120 da
134 -NHEJ to be strictly dependent on DNA Ligase IV, XRCC4 and XLF, members of the canonical branch of NH
136 ell transfusion and discuss using first-line IV iron monotherapy to treat anemic patients with cancer
138 thanide (Ln) ions, molecular complexes of Ln(IV) were known only for cerium and more recently terbium
140 Pt(IV) aryl complexes (Ar = p-FC(6)H(4)) LPt(IV)F(py)(Ar)X (X = CN, Cl, 4-OC(6)H(4)NO(2)) and LPt(IV)
141 (Ar)X (X = CN, Cl, 4-OC(6)H(4)NO(2)) and LPt(IV)F(2)(Ar)(HX) (X = NHAlk; Alk = n-Bu, PhCH(2), cyclo-C
146 and multifrequency EPR spectroscopy of a Mn(IV)(4)O(4) cuboidal complex as a spectroscopic model of
147 sults indicate the amounts of Mn(III) and Mn(IV) species in MnO(x) and CaMnO(3) depend on potential.
149 idation of the previously reported Mn(III)Mn(IV)(3)O(4) cuboidal complex to the Mn(IV)(4)O(4) complex
153 4 patients with MPS II, 9 patients with MPS IV, and 6 patients with MPS VI) and 20 normal control su
155 confirming the generality of the Ni(II) -> N(IV) protocol, either in the presence of bipyridine, or u
160 ied the junctional receptor CNTNAP4/Neurexin-IV (Nrx-IV) and the membrane cytoskeletal effector Adduc
162 ts demonstrate the superiority of COOH-NHMe (IV) in detecting more lipid and protein species compared
164 junctional receptor CNTNAP4/Neurexin-IV (Nrx-IV) and the membrane cytoskeletal effector Adducin/Hu-li
165 charge, and (3) received a partial course of IV antibiotics and were prescribed oral antibiotics on A
166 ntibiotics, (2) received a partial course of IV antibiotics but were not prescribed any antibiotics o
168 years or older with resected stage IIIB-C or IV melanoma and an Eastern Cooperative Oncology Group pe
169 ographic findings at discharge (grade III or IV aortic regurgitation, pulmonary hypertension) identif
171 s appropriate for patients with Stage III or IV periodontitis and can be recommended in dental practi
173 65% New York Heart Association Class III or IV, nearly all on a loop diuretic, and 70% with a HF hos
174 New York Heart Association class II, III, or IV) and an ejection fraction of less than 45% to receive
177 (geometric least-squares mean [LSM]) of oral/IV 5-day area under curve from time 0 to last measurable
179 e and isolable OCO pincer-supported alkyl-Pd(IV) complexes containing cyclopalladated alkylamine and
180 ich represent the first examples of alkyl-Pd(IV) complexes derived from the oxidation of cyclopallada
182 ization reactions, though few examples of Pd(IV) complexes containing cyclopalladated substrates have
183 I) intermediate to high-valent Pd(III) or Pd(IV) intermediates, which promotes the formation of C-O b
185 ivated by the action of dipeptidyl peptidase IV (DPP-4) which limits their use as therapeutic agents.
186 erting enzyme (ACE) and dipeptidyl peptidase IV (DPP-IV) inhibitory activities, with inhibition of AC
187 e, we introduce conjugation between platinum(IV) prodrugs of cisplatin and perfluoroaryl peptide macr
189 vation can up-regulate and activate DinB/pol IV, the bacterial ortholog of Polkappa, to induce mutage
190 liana), DNA-dependent RNA polymerase IV (Pol IV) is required for the formation of transposable elemen
193 f NRPD1, encoding the largest subunit of Pol IV, in the Brassicaceae species Capsella (Capsella rubel
198 psis thaliana), DNA-dependent RNA polymerase IV (Pol IV) is required for the formation of transposabl
201 -ALL cells, the leukemia-prone TAL1 promoter-IV specifically interacts with the +19 stem cell enhance
202 ive elimination from a series of isolated Pt(IV) aryl complexes (Ar = p-FC(6)H(4)) LPt(IV)F(py)(Ar)X
203 ive elimination reactions of all isolated Pt(IV) complexes follow first-order kinetics and were model
205 f Pu-UiO-66 demonstrates adept control of Pu(IV) coordination under hydrolysis-prone conditions, prov
208 in crus I, paraflocculus, and vermal regions IV/V and VI - highlighting these regions as potential hu
210 rome (IBS), respectively, as defined by Rome IV criteria; and, 2) relationships between nausea and mu
211 oms of constipation not included in the Rome IV criteria, such as daily failure to defecate and an av
214 hase laboratory experiments coupled to the S(IV)-autooxidation chemistry of isoprene, 3-methyl-2(5H)-
215 ly via the Wechsler Adult Intelligence Scale IV (IQ range, 40-160, standardized to a mean of 100 [SD,
216 Single-cell RNA sequencing showed that SNP-IV induced stem-like genes (Tcf7, Slamf6, Xcl1) whereas
218 trated complete clinical response in a Stage IV MCC patient treated with PI3K inhibitor idelalisib.
219 c factors, although the guidelines for stage IV disease do not account for how these factors may infl
224 nase inhibitors (TKI), the majority of stage IV melanoma patients eventually succumb to the disease.
225 patients with resected stage IIIB-C or stage IV melanoma, showed significant improvements in recurren
226 levated lactate dehydrogenase level or stage IV) or acute leukemia to compare the addition of six dos
228 ts were diagnosed at stages other than stage IV; for 19 of the 20 studied symptoms (all except for ne
230 le patients and 77 male patients) with stage IV CRC who underwent molecular profiling and pretreatmen
231 rospectively included 79 patients with stage IV lung carcinomas (n=24), renal carcinomas (n=11), or m
234 le patients were aged 18-80 years with stage IV melanoma with no evidence of disease after surgery or
235 on systemic therapy for patients with stage IV non-small-cell lung cancer (NSCLC) without driver alt
237 II) study of different successional stages, (IV) use of environmentally relevant concentrations of bi
240 a simple, readily-accessible alkyl sulfinyl (IV) chloride allows formation of a trigonal bipyramidal
243 de like hematite at pH 6.00 +/- 0.07, and Tc(IV) incorporation into magnetite via Fe(III) substitutio
244 quent inner-sphere complexation of Tc(IV)-Tc(IV) dimers onto a Fe oxide like hematite at pH 6.00 +/-
245 d subsequent inner-sphere complexation of Tc(IV)-Tc(IV) dimers onto a Fe oxide like hematite at pH 6.
246 sm involves the reduction from Tc(VII) to Tc(IV) and subsequent inner-sphere complexation of Tc(IV)-T
249 rsistent faradaic current peaks dominate the IV cycle of the junction (+/-2 V) in ACN vapor, enhancin
251 re classified as having an FTP grade of I to IV, and the velum, oropharynx, tongue base, epiglottis (
252 ent in outcomes of patients with stage II to IV DAWT compared with historical controls treated with r
253 nts aged at least 12 years with grades II to IV steroid-refractory aGVHD were eligible to receive rux
254 ork Heart Association functional class II to IV with a left ventricular (LV) ejection fraction <=40%
259 sk for follicular carcinoma in Bethesda type IV thyroid nodules but their absence does not allow to p
265 in the gonadal BM, where it facilitates type IV collagen removal during BM expansion and tissue growt
266 hatases; a set of 20 genes required for type IV pili function; and several conditionally essential ge
267 ubsequent pathology require the Dot/Icm Type IV Secretion System (T4SS) to deliver effector proteins
268 niche, C. burnetii requires the Dot/Icm type IV secretion system (T4SS) to translocate a cohort of ef
269 patients tend to have plateau iris; MPS type IV patients are vulnerable to open-angle glaucoma; MPS t
270 construct using the dynamic activity of type IV competence pili in V. cholerae as a model system.
272 h diversity microbiota, Community State Type IV-B, was the most prevalent in both HIV-negative (38% a
274 Caulobacter crescentus We identify the type IV pilin protein PilA as the primary signaling input tha
275 r tetracycline resistance [tet(O)], the Type IV secretion system, conjugative transfer and the Type V
278 quiv of HNEt(3)BPh(3) yielded the cationic U(IV)/U(IV) nitride complex, [{((Me(3)Si)(2)N)(2)U(THF)}(2
279 th H(2) to produce an imide hydride U(III)/U(IV) complex, [{((Me(3)Si)(2)N)(2)U(THF)}(2)(mu-NH)(mu-H)
280 able to reduce soluble U(VI) to insoluble U(IV), providing a method for removal of U from contaminat
281 Treatment of the previously reported U(IV)/U(IV) nitride complex [Na(DME)(3)][((Me(3)Si)(2)N)(2)U(mu-
282 f HNEt(3)BPh(3) yielded the cationic U(IV)/U(IV) nitride complex, [{((Me(3)Si)(2)N)(2)U(THF)}(2)(mu-N
283 final speciation of U was nanoparticulate U(IV) uraninite, and this phase was evident at 2 days at p
287 Further FLP reactivity between the uranium(IV)-amide, dihydrogen, and triphenylborane is suggested
289 on spectroscopy revealed V(V) reduction to V(IV) and formation of bidentate corner-sharing surface co
292 compare adverse event rates associated with IV iron vs red cell transfusion and discuss using first-
294 e linked to Medicare claims and treated with IV tPA at Get With The Guidelines-Stroke hospitals (Febr
295 We identified 293 patients treated with IV tPA who had a prior ischemic stroke within 3 months a
297 The self-assembly of highly stable zirconium(IV)-based coordination cages with aggregation induced em
298 moisture-stable, visible light-absorbing Zr(IV) photosensitizer, Zr((Mes)PDP(Ph))(2), where [(Mes)PD
299 eport a new light-harvesting mixed-ligand Zr(IV)-based metal-organic framework (MOF),with underlying
300 Consecutive layer-by-layer addition of Zr(IV)-bridged methylenediphosphonic acid enabled positioni