ライフサイエンスコーパス: IgM

1 IgM also decreased expression of RIM101 and HOG1, genes

2 IgM and serum PCR are 61% concordant; serum and urine PC

3 IgM anti-PC levels develop much slower than anti-MDA and

4 IgM levels normalized in seven of the eight infants, of

5 IgM(+) B1b B cells include IRA-like and non-IRA B cells

6 assay (ICA), and the InBios ZIKV Detect 2.0 IgM antibody capture enzyme-linked immunosorbent assay (

7 .5% (17.5% IgM+IgG+, 9.0% IgM+IgG-, and 5.0% IgM-IgG+).

8 roprevalence was 31.5% (17.5% IgM+IgG+, 9.0% IgM+IgG-, and 5.0% IgM-IgG+).

9 munosorbent assays to detect anti-SARS-CoV-2 IgM and IgG antibodies in 5-d time intervals from sympto

10 d that they were positive for the SARS-CoV-2 IgM and IgG antibodies.

11 luated using the Abbott Architect SARS-CoV-2 IgM assay.

12 ogy of larger cohorts (n = 3494 IgA; n = 397 IgM).

13 The seroprevalence was 31.5% (17.5% IgM+IgG+, 9.0% IgM+IgG-, and 5.0% IgM-IgG+).

14 e ELISAs were 83% (IgA), 98% (IgG), and 97% (IgM and total antibody).

15 Abbott IgG, Roche total antibody, and Abbott IgM assays, respectively, with sampling times 0 to 56 da

16 Qualitative agreements with the Abbott IgM assay were 92.7% (51/55, Abbott IgG) and 85.5% (47/5

17 kin plasma cells supply natural and adaptive IgM to the cutaneous environment, thereby supporting hom

18 In addition, IgM-mediated Salmonella uptake was decreased, and MIICs

19 b, which further interacts with the adjacent IgM-Fab(2) and globular C1q-recognition unit.

20 syncytial virus and HIV-1 also exhibited an IgM(LOW) IgD(+) phenotype, which is associated with self

21 haracterized by conventional NS1 antigen and IgM antibody ELISA kits.

22 urface immunoglobulin M (IgM) expression and IgM-signaling response but high CXCR4 expression, indica

23 ed the anti-glycan immunoglobulin (Ig) G and IgM responses in vaccinated and challenged baboons over

24 In addition to immunoglobulin (Ig)G and IgM serology and traditional reverse-transcription polym

25 All women had CMV immunoglobin (Ig) G and IgM testing at 11-14 weeks of each pregnancy.

26 ture anti-dsDNA autoantibodies (IgG, IgA and IgM AAbs) present in the sera of patients with rheumatoi

27 test results who also had T. gondii IgA and IgM antibody tests performed.

28 e 71 women who were positive by both IgA and IgM antibody tests, 61 (85.9%) were acutely infected, wh

29 had significantly higher total serum IgA and IgM compared to controls, based on serology of larger co

30 e-COVID-19 era were tested for IgG, IgA, and IgM to the antigen panel.

31 Total IgG and IgM Ab levels were determined via ELISA.

32 cells and microbes, we profiled the IgG and IgM ACARs from all donors.

33 study investigates the prevalence of IgG and IgM antibodies to SARS-CoV-2 in Los Angeles County, Cali

34 detection of parasite-specific human IgG and IgM antibodies, respectively.

35 DL) for in-depth immune profiling of IgG and IgM antibody repertoires in serum and urine longitudinal

36 ing for IgA and IgG avidity, if both IgG and IgM are positive.

37 Some patients showed high levels of IgG and IgM autoantibodies against numerous autoantigens, and so

38 cence microscopy showed normal human IgG and IgM bind C. neoformans (ii) C. neoformans grown in titan

39 IgG and IgM detection probabilities increase from roughly 10% at

40 This lateral-flow assay detects IgG and IgM isotypes that are specific to the SARS-CoV-2 recepto

41 hout any seroconversion, Chikungunya IgG and IgM levels were higher, long-term IgM positivity and rad

42 o reveal that seroconversion of both IgG and IgM occurs around 12 days post-symptom onset (range 1-40

43 for detection of SARS-CoV-2 specific IgG and IgM patient antibodies, along with the necessary sample

44 IgG and IgM present in the blood of Lassa fever survivors from N

45 Combining IgG and IgM screening identified 4/55 additional samples with de

46 o ordered testing only for T. gondii IgG and IgM should also request additional testing for IgA and I

47 All women had CMV IgG and IgM testing at 11-14 weeks' of each pregnancy.

48 with C1q fixation, and both purified IgG and IgM were capable of mediating C1q fixation to PvMSP3alph

49 that detects Aspergillus antibodies (IgG and IgM) in less than 30 min, requiring minimal laboratory e

50 SARS-CoV-2-specific IgA, IgG, and IgM Ab levels positively correlated with SARS-CoV-2-neut

51 onths underwent measurement of IgA, IgG, and IgM against TCD toxins A and B and neutralizing antibody

52 he paracortex, which expressed IgE, IgG, and IgM but not IgA.

53 protein S1 domain (EUROIMMUN); IgA, IgG, and IgM indirect ELISAs to detect the full-length S protein

54 hocytes demonstrated decreased IgA, IgG, and IgM production in EdnrB(NCC-/-) vs. WT mice.

55 ormation about total Ig, as well as IgG- and IgM-specific responses.

56 Serum anti-GD2 (immunoglobulin G1 [IgG1] and IgM) and anti-GD3 (IgG1) titers showed notable increases

57 IgG1, IgG3, and IgM were significantly correlated with C1q fixation, and

58 cant inverse associations between C-IRIS and IgM (P = .0003), Lam-IgM (P = .0005), Lam-IgG (P = .002)

59 ns are evaluated; 161 sera tested by PCR and IgM assays, 85 urines by PCR.

60 ollicular T-bet(+) CD11c(+) plasmablasts and IgM memory B cells.

61 In addition, whereas stimulation with anti-IgM or anti-Igkappa L chain Abs resulted in strong pCD79

62 ent did not affect anti-Leishmania antibody (IgM, IgG, IgG1 and IgG2a) or IL-10 production, but anti-

63 g analytical performance of ox-GCE/AuNPs-ARG/IgM was confirmed by quantifying DHEAS in real patient p

64 The construction of ox-GCE/AuNPs-ARG/IgM was optimized through factorial design and response

65 d anti-DHEA IgM antibodies (ox-GCE/AuNPs-ARG/IgM).

66 capture enzyme-linked immunosorbent assays (IgM-ELISAs), and inhibition ELISAs to detect pre- and po

67 Here, we show that these TLF2-associated IgMs interact with both HPR and alternate trypanosome su

68 germline antibodies such as TLF2-associated IgMs play a role in antimicrobial immunity.

69 waned rapidly, whereas swIg(+) and atypical IgM(+) and IgD(+) MBCs were stable over time.

70 e highly penetrant secretion of autoreactive IgM antibodies.

71 so block recognition of NTHi by bactericidal IgM and complement by mechanisms that are not fully unde

72 binding by naturally occurring bactericidal IgM in serum and are protected by sialylation of the LOS

73 Concordance between IgM and PCR results is 52%, sensitivity 65%, specificity

74 PfEMP1 variants per parasite genome can bind IgM via the Fc part of the antibody molecule, and which

75 on, and then isolated individual IEs binding IgM from malaria-unexposed individuals by fluorescence-a

76 capsule-specific and laminarin (Lam)-binding IgM and IgG, and percentages of peripheral blood total a

77 o initiation of ART, plasma IgM, Lam-binding IgM (Lam-IgM), Lam-IgG, and GXM-IgM levels were signific

78 C1 binds IgM through widely spread C1q-collagen helices, with C1r

79 Furthermore, BM IgM production and plasma IgM levels were reduced in Apo

80 Both IgM anti-PC and anti-MDA increased during the first 2 y

81 Both IgM hexamers and pentamers adopted hexagonal, dome-shape

82 /6J mice using these particles elicited both IgM and class-switched IgG1, IgG2b, and IgG3 autoreactiv

83 immunoglobulin sequences and isotypes (both IgM and IgG), including a high frequency of monoclonal a

84 How antigen-bound IgM activates complement-immune responses remains unclea

85 levels were similar between age groups, but IgM was predominant in children and IgG3 more prevalent

86 increased during the first 2 y of life, but IgM anti-PC in contrast to IgM anti-MDA was still signif

87 d lgtC each add a galactose epitope bound by IgM that results in antibody-dependent killing via the c

88 nd scCOVID, p-value<0.001), anti-Cardiolipin IgM (sdCOVID, P=0.003; scCOVID, P<0.001), and anti-Beta2

89 (PtC)-specific (PtC(+)) peritoneal B-1a cell IgM does not change with age.

90 de the first report of a unique BM B-1a cell IgM repertoire and identifies CXCR4 expression as a crit

91 itment of cytotoxic CD8+ T cells, Th1 cells, IgM+ B cells, and plasma cells.

92 tiplexed detection of dengue and chikungunya IgM/IgG antibodies in human clinical samples within 30 m

93 Furthermore, the long-term Chikungunya IgM positivity we observed in some cases might corrobora

94 swIg(+)) MBC populations; however, classical IgM MBCs waned rapidly, whereas swIg(+) and atypical IgM

95 chusetts, by BioMedomics SARS-CoV-2 combined IgM-IgG point-of-care lateral flow immunoassay.

96 robiota via high-level coating, compensatory IgM in sIgAd subjects showed less specificity than IgA a

97 Despite the secretion of compensatory IgM into the gut lumen, sIgAd subjects displayed an alte

98 both the S1 and S2 subunits, and concomitant IgM and IgA antibodies, lasting throughout the observati

99 ected subjects had higher levels of anti-CSP IgM.

100 counterparts in lymphoid tissues, cutaneous IgM-secreting cells were completely dependent on surviva

101 gold nanoparticles (AuNPs-ARG) and anti-DHEA IgM antibodies (ox-GCE/AuNPs-ARG/IgM).

102 d a shift from IgD(+)IgM(dim) toward IgD(dim)IgM(+) B cell populations in spleen, peritoneum and peri

103 sed populations of B-1 cells (B220(+)IgD(dim)IgM(+)CD43(+)CD24(+)CD5(+)), and higher numbers of immat

104 higher numbers of immature B cells (IgD(dim)IgM(dim)CD21(neg)) at the expense of mature B cells (IgD

105 n afforded by IgA arising from either direct IgM-to-IgA or sequential IgM-to-IgG-to-IgA class switchi

106 year, despite undetectable virus, a diverse IgM repertoire against VP40 and GP epitopes is observed

107 We observe a very diverse IgM immune repertoire encompassing the entire ZIKV polyp

108 there was deposition of at least 1 of either IgM, IgG, IgA, or C3 at the basement membrane of the spe

109 IgG titers were greater than either IgM or IgA titers for S1, full-length S, and S-RBD in th

110 Elevated IgM, but not IgG or IgA, autoantibodies were significant

111 lineages and reduced serum IgA and elevated IgM levels across multiple ages.

112 cells, the liposomal particles also elicited IgM, IgG1, IgG2b, and IgG3 responses that were comparabl

113 zation of C3ar1(-/-)C5ar1(-/-) mice elicited IgM Ab but no other isotypes, whereas decay accelerating

114 that secrete high titers of germline-encoded IgM autoantibody and hypermutating germinal center B cel

115 umoral defence network that also encompasses IgM, IgG and IgD.

116 d T-cell activation), with decreased EndoCAb IgM.

117 Furthermore, an enhanced IgM assay was supplemented to improve the test's detecti

118 not known whether such patients also exhibit IgM or IgA autoantibodies against FceRIalpha.

119 rred at a median of 12.5 days (IQR 9-18) for IgM and 15.0 days (IQR 12-20) for IgG; 54/62 patients (8

120 ELISA was positive in 84/295 (28.4%) for IgM and 86/295 (29.1%) for IgG, and immunoblot was posit

121 mmunoblot was positive in 21/191 (10.9%) for IgM and 50/191 (26.1 %) for IgG.

122 ted by enzyme-linked immunosorbent assay for IgM, IgG, and IgA anti-SARS-CoV-2 antibodies.

123 was selectively required for IgG but not for IgM production.

124 Differential kinetics are observed for IgM-IgG-IgA epitope diversity, antibody binding, and aff

125 Hyalinous lesions were positive for IgM and iC3b/c/d, indicating subendothelial leakage of p

126 ell tetramers and intracellular staining for IgM, IgG, and IgA isotypes, we were able to derive and c

127 mercial preparations of IVIg were tested for IgM and IgG binding to red blood cells (RBCs) from wild-

128 ed during malaria infections, initially from IgM(+) and then from IgG(+) B1b B cell plasmablasts, whi

129 ixing antibodies and immunoglobulin M and G (IgM and IgG), targeting 3 distinctive regions of PvMSP3a

130 FM influenced the levels of ALP, AMY, GLOB, IgM, and MDA (P < 0.05).

131 Anti-glycan IgM responses developed early after vaccination, but did

132 Anti-GM1 IgM antibodies are identified in at least 40% of patient

133 OWMs had significantly greater IgM binding and cytotoxicity to TKO PBMCs than humans or

134 IgM (P = .0005), Lam-IgG (P = .002), and GXM-IgM (P = .002) independent of age, sex, HIV viral load,

135 Lam-binding IgM (Lam-IgM), Lam-IgG, and GXM-IgM levels were significantly lower in patients who deve

136 ude plasma IgM, Lam-IgM, Lam-IgG, and/or GXM-IgM may have value in furthering our understanding of C-

137 More than half of patients had IgM (21/35, 60%) and IgA (20/35, 57%) vs (3/52, 5%) each

138 Our data show human IgM affects C. neoformans morphology in vitro and sugges

139 y cytokines, chemokines and specific humoral IgM and IgG responses.

140 ID-G4 binding modeled the pathology of hyper-IgM syndrome patients with an orthologous mutation, lack

141 D40L that induce immunodeficiency with hyper-IgM syndrome type 1 (HIGM1) are clustered in the integri

142 Clonally expanded, somatically hypermutated IgM+ and IgG1+ CSF B cells were associated with inflamma

143 IgA, IgM, and IgG and neutralizing antibody responses were qu

144 mplexes, with no anticipated effects on IgA, IgM, IgE, complement, plasma cells, B cells, or other ce

145 eg)) at the expense of mature B cells (IgD(+)IgM(+)CD21(+)).

146 on of marginal zone (MZ)-like B cells (IgD(+)IgM(+)CD43(neg)CD21(+)CD24(+)), increased populations of

147 KCbetaIItg mice displayed a shift from IgD(+)IgM(dim) toward IgD(dim)IgM(+) B cell populations in spl

148 antify the levels of immunoglobulin G (IgG), IgM and IgA antibodies against four SARS-CoV-2 antigens.

149 19 symptoms, negative immunoglobulin G (IgG)-IgM SARS-CoV-2 serology, and positive RNAemia measured b

150 itation (LIPS) assays, we characterized IgG, IgM, and IgA antibodies to the spike receptor binding do

151 a newly developed competitive ELISA for IgG, IgM, and IgA autoantibodies to FceRIalpha.

152 owed significantly decreased glomerular IgG, IgM, and C3 deposits.

153 oped an ELISA to assess serum levels of IgG, IgM, and IgA autoantibodies against FceRIalpha and inves

154 ult COVID-19 cohorts had anti-spike (S) IgG, IgM and IgA antibodies, as well as anti-nucleocapsid (N)

155 that COVID-19 patients make high titer IgG, IgM, and IgA Ab responses to the Cys-like protease from

156 R Diagnostic Panel, Cellex's qSARS-CoV-2 IgG/IgM Rapid Test, and point-of-care tests such as Abbott's

157 led secondary antibodies (HRP-anti-human IgG/IgM/IgA mixture).

158 or patients with acute LF (RDT positive, IgG/IgM negative) during initial screening, RDT performance

159 ed by both classical immunoglobulin M (IgM) (IgM(+)CD27(+)) and switched immunoglobulin (swIg(+)) MBC

160 antioxidants (SOD, GPx and GSH), and immune (IgM and lysozyme) parameters in LMB, except ALP and CAT.

161 rmal (HPT) processing on the immunoglobulin (IgM, IgA and IgG), and cytokine content (IL-6, IL-8, IL-

162 e observed elevated Ig-levels, distortion in IgM(+) B cells, increase in double negative B cells, cha

163 ced IgM memory B cell levels, and studies in IgM- and/or B cell-deficient mice have demonstrated incr

164 was predominantly affected by variability in IgM results.

165 ainst oxidation specific epitopes, including IgM specific for malondialdehyde-modified LDL (low-densi

166 depends on soluble serum proteins, including IgM.

167 lation of phagocytic receptors and increased IgM production, and decreased brain inflammatory respons

168 1) and the diagnostic sensitivity of initial IgM fell from 93% to 81% (P = .012), respectively.

169 olleagues demonstrate that triggering innate IgM-mediated B-1a immune responses via pathogen- or dang

170 This B-cell subset is IgM(+), but due to low/negative IgD cell surface express

171 Mycoplasma pneumoniae ASCs of the isotype IgM were found in 29 (46%), IgG were found in 27 (43%),

172 ) B-1a cell population does not preserve its IgM germline status in the aged mice.

173 Moreover, the anti-Mtb LAM IgM bound sensor probes and the AuNP reagent stored at 4

174 ions between C-IRIS and IgM (P = .0003), Lam-IgM (P = .0005), Lam-IgG (P = .002), and GXM-IgM (P = .0

175 ion of ART, plasma IgM, Lam-binding IgM (Lam-IgM), Lam-IgG, and GXM-IgM levels were significantly low

176 tibody profiles that include plasma IgM, Lam-IgM, Lam-IgG, and/or GXM-IgM may have value in furtherin

177 ns non-covalently associated immunoglobin M (IgM) antibodies, the role and origin of which remain unc

178 mediated by both classical immunoglobulin M (IgM) (IgM(+)CD27(+)) and switched immunoglobulin (swIg(+

179 onalized with anti-Mtb LAM immunoglobulin M (IgM) and anti-Mtb LAM IgG respectively.

180 e to NiV by virus-specific immunoglobulin M (IgM) and immunoglobulin G (IgG) enzyme-linked immunosorb

181 immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies in Malaysian patients with vivax, falcip

182 immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies was undertaken under medical supervision

183 in 1 (NS1) in the standard immunoglobulin M (IgM) antibody-capture enzyme-linked immunosorbent assay

184 Ki-67, CD49d, cell-surface immunoglobulin M (IgM) expression and IgM-signaling response but high CXCR

185 trated that clustering the immunoglobulin M (IgM) isotype of BCR with an artificial soluble cross-lin

186 et it generates protective immunoglobulin M (IgM) memory B cells (MBCs) that express the transcriptio

187 ESA) blot for detection of immunoglobulin M (IgM)-specific shed acute phase antigen (SAPA) bands, usi

188 of immunoglobulin-G (IgG), immunoglobulin-M (IgM), and in vitro neutralizing antibody titers in COVID

189 uropathy, ophthalmoplegia, immunoglobulin M [IgM] paraprotein, cold agglutinins, and disialosyl antib

190 xin core antibody (EndoCAb immunoglobulin M [IgM]) in plasma.

191 ation of neutrophils, and immunoglobulin M+ (IgM+) B cells.

192 tor weakness in the presence of a monoclonal IgM reacting against gangliosides containing disialosyl

193 All patients had serum monoclonal IgM gammopathy (median, 2.6 g/L; range, 0.1-40 g/L).

194 r immunological properties of the monoclonal IgM.

195 ansforming growth factor beta, while mucosal IgM is significantly increased in the setting of CD4(+)

196 ntribute to the actual and available natural IgM repertoire with increasing age.

197 B-1 cell-derived natural IgM antibodies against oxidation-specific epitopes on lo

198 ls to rapidly produce high levels of natural IgM reactive against tumor-associated carbohydrate antig

199 suspected role for B-1 cell-produced natural IgM in providing protection against tumor growth in the

200 They are the main producers of 'natural' IgM, spontaneously secreted serum antibodies predominate

201 at diagnosis: IgG negative (-) (nonimmune), IgM+/IgG+ (indeterminate), or IgM-/IgG+ (waning immunity

202 th glycoprotein (GP)-specific T-cell but not IgM or IgG antibody responses.

203 (iii) Absorption of IgM with laminarin or curdlan (branched and linear 1-3-b

204 mmation promoted the massive accumulation of IgM-secreting cells, and cutaneous immunization directed

205 ith this, we found significant deposition of IgM and C3 on peritoneal tumor cells as early as 5 days

206 tiplex bead-based assay for the detection of IgM and IgG antibodies to B. burgdorferi The BioPlex 220

207 bulin isotypes, with successful detection of IgM, IgG and IgA antibody-antigen interactions.

208 acterial vaccine revealed unique dynamics of IgM and IgT repertoires at systemic and mucosal sites an

209 rospective study to evaluate the efficacy of IgM-enriched immunoglobulin (IgMIg) on 30-day mortality

210 CXCL10 peaked with emergence of IgM antibodies and was elevated in hospitalized patients

211 nd were measured at the beginning and end of IgM treatment.

212 igens, confirmed by the detection by flow of IgM and IgG (mostly IgG1 and IgG4) anti-CD4+ cell Abs in

213 t children were born with very low levels of IgM anti-PC, whereas IgM anti-MDA was present at birth.

214 positively associates with plasma levels of IgM antibodies specific for malondialdehyde-modified LDL

215 Increased serum levels of IgM-anti-FceRIalpha are common in patients with CSU and

216 Also, elevated levels of IgM-anti-FceRIalpha, but not of IgG or IgA against FceRI

217 al culture, serum samples for measurement of IgM/IgG levels (n=30), and plasma samples for levels of

218 enoids originate from a unique population of IgM(+) and/or IgD(+) memory B cells that contain a high

219 rning BM B-1a localization and production of IgM against oxidation specific epitopes.

220 ction progresses, the relative proportion of IgM(+) B1 B cells decreases while that of IgG(+) plasmab

221 herosclerosis express a unique repertoire of IgM antibodies containing increased nontemplate-encoded

222 IgM production, yet the unique repertoire of IgM antibodies generated by BM B-1a and the factors main

223 ed the possibility that mucosal secretion of IgM can compensate for a lack of secretory IgA.

224 ntrol trout suggests different structures of IgM and IgT spleen and NALT repertoires, with restricted

225 resent cryoelectron tomography structures of IgM, C1, and C4b complexes formed on antigen-bearing lip

226 interactive effect (P = 0.016) was found on IgM only, with lower levels in fish fed diet 12 (low-FM,

227 cell survival, with differential impacts on IgM- and IgG-producing populations.

228 We identified one IgM/IgG negative participant who had PBMCs which produce

229 ptase polymerase chain reaction (PCR) and/or IgM Zika MAC-ELISA.

230 IgG, but not IgA or IgM, transferred through breast milk to the intestinal l

231 Hcp1 IgG (0.92) compared to anti-Hcp1 IgA or IgM.

232 ) (nonimmune), IgM+/IgG+ (indeterminate), or IgM-/IgG+ (waning immunity).

233 al-time reverse transcription-PCR (rRT-PCR), IgM capture enzyme-linked immunosorbent assays (IgM-ELIS

234 with earlier seroconversion and higher peak IgM and IgG levels.

235 We measured anti-pig IgM/IgG binding, and complement-dependent cytotoxicity t

236 a cells increased BM localization and plasma IgM against oxidation specific epitopes, including IgM s

237 Furthermore, BM IgM production and plasma IgM levels were reduced in ApoE(-/-) mice with B-cell-sp

238 Prior to initiation of ART, plasma IgM, Lam-binding IgM (Lam-IgM), Lam-IgG, and GXM-IgM lev

239 Antibody profiles that include plasma IgM, Lam-IgM, Lam-IgG, and/or GXM-IgM may have value in

240 t with either positive Mycoplasma pneumoniae IgM or PCR testing from January 1, 2010, until December

241 ses of positive IgG and one case of positive IgM as well as IgG antibodies.

242 This includes nine cases of positive IgM, two cases of positive IgG and one case of positive

243 We show that 'resisters' possess IgM, class-switched IgG antibody responses and non-IFN-g

244 al-time qPCR were used to identify potential IgM-binding PfEMP1 variants.

245 type switching of GM-CSF- and IL-3-producing IgM(+) B1 B cells.

246 PS IgM and IgG antibodies were elevated in patients with vi

247 PS IgM and IgG were also increased in volunteers infected w

248 In vivax and falciparum malaria, PS IgM and IgG on admission correlated inversely with admis

249 When compared to qPCR, IgM TESA blot was both sensitive and specific for congen

250 between cryptococcal meningitis and reduced IgM memory B cell levels, and studies in IgM- and/or B c

251 Rheumatoid factors (RFs)-IgM and -IgA were measured by ELISA.

252 Although robust IgM and IgA responses evolved in both survivors and non-

253 Mice unable to secrete IgM or complement component C4 were not protected by MPL

254 Seventeen people had SEOV IgM, indicating recent infection; 7 reported symptoms an

255 from either direct IgM-to-IgA or sequential IgM-to-IgG-to-IgA class switching.

256 te that an initial infection induced a serum IgM and mucosal IgA response against the toxin, but a lo

257 s and human herpes virus-6 measured by serum IgM, high titre IgG or clinical disease may be associate

258 heless, DeltadblGATA mice had elevated serum IgM with decreased IgG1 and IgG2a whether mice were chal

259 l array to explore binding activity of serum IgM in healthy persons and NSCLC patients at different c

260 e study that included 45 patients with serum IgM antibodies reacting against disialosyl epitopes in t

261 patients who showed high SARS-CoV-2 specific IgM and IgG levels.

262 -dependent and -independent antigen-specific IgM-secreting cells into skin.

263 blood by qRT-PCR, and for anti-EBOV-specific IgM and IgG antibodies by enzyme-linked immunosorbent as

264 termined that the measurement of Mp-specific IgM antibody-secreting cells (ASCs) by enzyme-linked imm

265 ndividuals developed detectable NiV-specific IgM and IgG antibodies within a week of disease onset.

266 or dengue infection by viral RNA or specific IgM antibodies in serum or CSF.

267 Parasite-specific IgM in mucus could only be elicited after challenge of t

268 e reliable predictor for a parasite-specific IgM response compared to SAG1, indicating that a bead-ba

269 d in our study developed both virus specific IgM and IgG antibodies as early as week one after diseas

270 onversion or a 4-fold rise in virus-specific IgM or IgG antibody titers from acute- and convalescent-

271 .9%), viral antigen (41.1%), and/or specific-IgM (63.2%).

272 anti-nucleocapsid protein IgG and anti-spike IgM assays are generally predictive of in vitro neutrali

273 ya IgG and IgM levels were higher, long-term IgM positivity and radiographic damage were more frequen

274 that substantially higher levels of IgG than IgM were produced per cell and that IgG(+) cells produce

275 Our data document that IgM-binding PfEMP1 proteins are common in each of the th

276 The IgM TESA blot for detection of SAPA bands is rapid, rela

277 The IgM-C1-C4b complexes revealed C4b product release as the

278 idylcholine lipids, a natural ligand for the IgM BCR expressed in the CH27 cells used.

279 in understanding how dual expression of the IgM and IgD BCR isotypes on mature naive follicular B ce

280 Mature naive B cells expressing BCRs of the IgM and IgD isotypes respond to Ag in secondary lymphoid

281 the 125 women who were positive by only the IgM ELISA were acutely infected (P < 0.001).

282 areas on protein N and S and showed that the IgM, A, and G Ab responses against receptor-binding doma

283 by ELISA and protein arrays to confirm their IgM-binding capacity.

284 Mean anti-TKO IgM was significantly higher in OWMs and significantly l

285 TLF2-IgMs are germline antibodies that, while present at basa

286 row (BM) B-1a cells contribute abundantly to IgM production, yet the unique repertoire of IgM antibod

287 ired for the differentiation of B-1 cells to IgM-producing plasmablasts after infections.

288 2 y of life, but IgM anti-PC in contrast to IgM anti-MDA was still significantly lower than in the m

289 derived phosphorylcholine-specific and total IgM moves away from germline (as evidenced by an increas

290 of immunoglobulin G (IgG), IgA, and usually IgM, together with loss of protective antibodies.

291 crochip device for assessing West Nile viral IgM antibody levels in human serum samples yielding anal

292 Most follicular B cells were IgM(+) (70-80%), but IgA(+) (and not IgG(+)) B-cell numb

293 01) were seropositive, and 60% of these were IgM+IgG-.

294 with very low levels of IgM anti-PC, whereas IgM anti-MDA was present at birth.

295 ptom onset to 98-100% by day 22, after which IgM wanes while IgG remains reliably detectable.

296 While IgM and IgA secretion by IghPax5/+ plasma cells was norm

297 on microscopy revealed that cells grown with IgM had small capsules and unique features not seen with

298 e genes showed that C. neoformans grown with IgM, not IgG or phosphate-buffered saline (PBS), had dec

299 ans grown in titan cell-inducing medium with IgM, not IgG, inhibited titan-like cell formation.

300 Furthermore, the MMB assays detected Zika IgM antibodies as early as 5 days and as late as 180 day

301 Among these are the Chembio DPP Zika IgM system (DPP Zika ICA; Chembio, Medford, NY), a rapid

302 able for detection of anti-Zika virus (ZIKV) IgM-class antibodies with U.S.