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1 LAMP is one of the most promising point-of-care (POC) ge
2 LAMP-2A is a transmembrane protein component for protein
3 LAMP-2A is required for chaperone-mediated autophagy (CM
4 LAMP-2B regulates lysosome maturation to impact macroaut
5 LAMP-2C levels modulated the steady-state expression of
6 LAMP-AuNP and LAMP-STR can detect as low as 9.7 fg (3.2
7 d by lysosome-associated membrane protein 1 (LAMP-1)-positive vesicles based on short hairpin RNA (sh
8 ociated with lysosomal-associated protein-1 (LAMP/gag) is a potential therapeutic vaccine against HIV
9 sosome associated membrane protein (LAMP)-1, LAMP-2 and the a2 isoform of V-ATPase (a2V, an enzyme in
10 in lysosomal-associated membrane protein 2 (LAMP-2) gene are associated with Danon disease, which of
11 cation using the lysosomal marker protein 2 (LAMP-2) immunolabeling showed higher neuronal lysosomal
12 the lysosome-associated membrane protein-2 (LAMP-2) regulate these pathways influencing immune recog
15 cking to facilitate cell-to-cell spread in a LAMP-1-dependent mechanism.IMPORTANCE MDV disrupts lipid
19 iated isothermal nucleic acid amplification (LAMP) and bioluminescent assay in real time (BART), with
20 via loop mediated isothermal amplification (LAMP) allowing for quantitative analysis of the cMYC pro
21 with loop-mediated isothermal amplification (LAMP) and a compact, portable, integrated microfluidic p
22 ning loop-mediated isothermal amplification (LAMP) and AC susceptometry, we demonstrate a rapid and h
23 ning loop-mediated isothermal amplification (LAMP) and disposable electrochemical sensors based on sc
24 sing loop-mediated isothermal amplification (LAMP) and provides real-time, naked-eye detection with H
25 ion: Loop-mediated isothermal amplification (LAMP) and Rolling Circle Amplification (RCA) techniques
27 sing loop-mediated isothermal amplification (LAMP) as the chemistry for targeted DNA detection, by vi
28 1&2 loop-mediated isothermal amplification (LAMP) assay (Meridian Bioscience, Cincinnati OH) for the
29 tric loop-mediated isothermal amplification (LAMP) assay and smartphone-based color analysis, enablin
30 ovel loop-mediated isothermal amplification (LAMP) assay based on the sequences available for the 13
31 y, a loop-mediated isothermal amplification (LAMP) assay provided rapid detection of SbGP/MPV phytopl
32 ed a loop-mediated isothermal amplification (LAMP) assay that enables rapid, low-cost detection of M.
33 of a loop-mediated isothermal amplification (LAMP) assay to facilitate rapid inexpensive molecular di
34 y, a loop-mediated isothermal amplification (LAMP) assay was designed for the specific detection of M
35 tric loop-mediated isothermal amplification (LAMP) assays targeting the L. loa-specific gene sequence
36 for loop-mediated isothermal amplification (LAMP) assays were identified from draft genomes of Calon
37 sing loop-mediated isothermal amplification (LAMP) combined with nanogold probe (AuNP) or styryl dye
41 with loop-mediated isothermal amplification (LAMP) for multiplexed instrument-free diagnosis of these
42 ital loop-mediated isothermal amplification (LAMP) for the detection and quantification of HPV DNA.
43 y of loop-mediated isothermal amplification (LAMP) for the detection of the BRAF V600E single-nucleot
50 sing loop-mediated isothermal amplification (LAMP) method and subsequently added to luminol solution
52 the loop-mediated isothermal amplification (LAMP) of nucleic acid biomarkers and shows for the first
53 les, loop-mediated isothermal amplification (LAMP) of nucleic acids, and visual readout of assays.
54 the loop-mediated isothermal amplification (LAMP) reaction which results in improved performance.
55 of a loop-mediated isothermal amplification (LAMP) reaction with an initial number of DNA strands as
56 izes loop-mediated isothermal amplification (LAMP) reagents predeposited into distinct lanes of the m
57 n of loop-mediated isothermal amplification (LAMP) targeting the waterborne pathogen Vibrio cholerae
58 e of loop-mediated isothermal amplification (LAMP) to detect PIK3CA c.3140 A > G (H1047R), a prevalen
59 ital loop-mediated isothermal amplification (LAMP) using commercially available microfluidic chips an
61 CR)/ loop mediated isothermal amplification (LAMP) was observed using the MTAT strategy (odds ratio [
62 (RT) loop-mediated isothermal amplification (LAMP) with clustered regularly interspaced short palindr
63 rate loop-mediated isothermal amplification (LAMP) with ECL technique for DNA detection and quantific
64 and loop-mediated isothermal amplification (LAMP) with end point detection using a hand-held UV sour
65 nts, loop-mediated isothermal amplification (LAMP), an extremely sensitive nucleic acid test, specifi
68 T]), loop-mediated isothermal amplification (LAMP), and quantitative reverse transcription polymerase
70 the loop mediated isothermal amplification (LAMP), are well suited for field use as they do not requ
71 ined loop-mediated isothermal amplification (LAMP), programmable toehold-mediated strand-exchange sig
72 h as loop-mediated isothermal amplification (LAMP), show great utility for the development of rapid d
73 with loop-mediated isothermal amplification (LAMP), the CHB probe could detect Borrelia burgdorferi (
75 cs for use with loop-mediated amplification (LAMP) as a bridge between concentrated and dilute templa
80 n this study we identify LAMP-1 (CD107a) and LAMP-2 (CD107b) on the surface of human monocyte-derived
81 that MDV gB colocalizes with cholesterol and LAMP-1, suggesting that viral protein trafficking is med
82 exhibited a striking accumulation of LC3 and LAMP-1 positive autolysosomes containing undigested cyto
83 of LAMP-SPR sensing was 10 copies/microl and LAMP-SPR sensing system showed a good selectivity toward
84 tion in LEs similar to that seen in NPC- and LAMP-deficient cells, we show that the restriction of pa
89 oop-mediated isothermal amplification assay (LAMP) for detection of HBV genotypes A, B, C, D, E, and
90 etection requirement, either in real-time at LAMP running temperature (~60 degrees C), or at end-poin
92 thus mainly focus on the paper device-based LAMP assay for the rapid infectious disease diagnosis, f
97 hat viral protein trafficking is mediated by LAMP-1-positive vesicles in association with cholesterol
103 mplification capacities of TPrA and combines LAMP with inherently high sensitivity of the ECL techniq
106 ults of adding swarm primers to conventional LAMP reactions include increased amplification speed, in
109 ound pork and 10 CFU/mL in milk in 5-7 days, LAMP-AuNP could detect down to 10 CFU/g for both samples
111 toplasm reactivity in a large fraction of DC-LAMP(+) cells, instead of the classical dot-like stain.
113 nts and a foundation for targeting defective LAMP-2B-mediated autophagy to treat this patient populat
114 a pool of candidate markers, we demonstrate LAMP assay specificity by testing related fungal species
115 main lamellar morphology, which we designate LAMP Transmission electron microscopy indicates that LAM
116 ophilic PDMS surfaces that allow for digital LAMP to be performed in a self-driven microfluidic devic
119 l the necessary workflows to perform digital LAMP using standard laboratory equipment and commerciall
120 As a proof of concept, we performed digital LAMP on a sp-SlipChip to quantify human papillomaviruses
126 more, B. neotomae exhibited early endosomal (LAMP-1) and late endoplasmic reticulum (calreticulin)-as
128 owever, the current LAMP methods, especially LAMP with two loop primers, suffer from undesired nonspe
131 will likely benefit most if not all existing LAMP assays based on state-of-the-art, six-primer reacti
133 on of paper into the microfluidic device for LAMP reactions enables stable test results over a much l
136 antees a significant and reliable signal for LAMP reaction amplified from as little as 10(-19) M viru
137 owever, common detection techniques used for LAMP and RT-LAMP have drawbacks, including poor discrimi
144 c loop-mediated isothermal amplification (iD-LAMP) and quantitative optical read-out by a disc drive.
148 o specific and non-specific amplification in LAMP that are difficult to deduce from bulk measurements
153 approach by testing variables that influence LAMP reaction speed and the probability of detection.
157 e virion-containing MCs emerged from larger, LAMP-1-positive membranous organelles that are morpholog
158 in addition to low-cost and robustness, make LAMP an attractive alternative to polymerase chain react
159 The performance of a commercial malaria LAMP assay (Illumigene Malaria LAMP) was evaluated using
161 rcial malaria LAMP assay (Illumigene Malaria LAMP) was evaluated using two sample preparation workflo
164 The performed work expands the use of MB-LAMP for SNP detection as well as demonstrates SPME as a
166 ess the diagnostic accuracy of meningococcal LAMP as a near-patient test in the emergency department.
167 s and tested with near-patient meningococcal LAMP and the results were compared with those obtained b
168 lations using Linkage Disequilibrium method (LAMP-LD) and evaluated the association with common carot
171 tibodies from all 8 patients bound to native LAMP-2 purified from human glomeruli and recombinant hLA
172 matrices such as human blood, using a novel LAMP primer set for bacteriophage MS2 (a model RNA virus
173 om M. smegmatis decreases the association of LAMP-3 with bead phagosomes, indicating that P27 itself
174 NA) gene silencing and the colocalization of LAMP-1, glycoprotein B (gB) of MDV, and cholesterol (fil
179 enomics-based approach to the development of LAMP diagnostic assays is the first of its kind for fung
181 sis for this is that real-time monitoring of LAMP reactions either by bioluminescent reporting (BART)
184 ion substantially reduced the reliability of LAMP and limited its applications in clinical diagnostic
186 In order to both improve the specificity of LAMP detection and to make readout simpler and more reli
189 respiratory and blood specimens with use of LAMP was accurate (sensitivity 89% [95% CI 72-96], speci
192 namic range quantification strategy based on LAMP, in a closed tube, undiluted sample molecular diagn
193 derived dendritic cells (MoDC) and show only LAMP-2 is internalized after ligation by specific Abs, i
194 ection of malaria parasites by microscopy or LAMP was not associated with adverse birth outcomes.
198 limits of detection of a few DNA copies per LAMP zone for N. meningitidis, S. pneumoniae and Hib wer
200 tions in a simple, inexpensive and portable "LAMP box" supplemented with a consumer class smartphone.
203 The lysosome-associated membrane protein (LAMP) family includes the dendritic cell endocytic recep
204 and DC-lysosome-associated membrane protein (LAMP), low levels of MIP1-beta/CCL4, MIG/CXCL9, and seve
205 ent of lysosome associated membrane protein (LAMP)-1, LAMP-2 and the a2 isoform of V-ATPase (a2V, an
206 ellular Salmonella recruit the host proteins LAMP-2A and Hsc73, key components of the host protein tu
207 d the lysosome-associated membrane proteins (LAMP) 1 and 2 are important for robust liver-stage P. be
210 iated isothermal DNA amplification reaction (LAMP) targeting a pathogenic bacteria gene, showing bene
216 n loop-mediated isothermal amplification (RT-LAMP) assay compatible with current reagents, which util
217 loop-mediated, isothermal amplification (RT-LAMP) assay for rapid detection of ZIKV and its implemen
218 n-loop-mediated isothermal amplification (RT-LAMP) assay, quantitative RT-PCR (qRT-PCR), and IgM- and
219 n-loop-mediated isothermal amplification (RT-LAMP) has frequently been proposed as an enabling techno
222 n loop-mediated isothermal amplification (RT-LAMP) was used subsequently to amplify the viral RNA.
223 n loop-mediated isothermal amplification (RT-LAMP) with our recently developed quenching of unincorpo
225 transcription, exponential amplification (RT-LAMP), and linear degradation (restriction enzymes) star
230 mbination with ELISA, both the RT-RPA and RT-LAMP assays increased the detection of acute DENV infect
232 on detection techniques used for LAMP and RT-LAMP have drawbacks, including poor discrimination capab
236 ction limit of the newly developed immuno-RT-LAMP assay was as low as 1.62x10(1) 50% embryo infectiou
238 mediated isothermal amplification (immuno-RT-LAMP) assay for the rapid detection of AIV H5N1 in whole
239 the exponential amplification ability of RT-LAMP and the sequence-specific processing by the CRISPR-
242 concordance (kappa of >/=0.723) with the RT-LAMP and qRT-PCR assays in detecting the dengue viremic
244 purification protocol, combined with the RT-LAMP assay, brings the sensitivity to at least 1 viral R
246 into the microfluidic chip to detect the RT-LAMP reaction product directly on the chip itself by mea
250 N1 gene was exponentially amplified using RT-LAMP on either a real-time PCR instrument for quantitati
251 mal amplification of SARS-CoV-2 RNA using RT-LAMP, the modified crRNAs are incorporated in a paper-ba
259 eru to establish the feasibility of using TB-LAMP (Eiken Chemical Co.) in microscopy laboratories com
260 nsmission electron microscopy indicates that LAMP exhibits ACBC domain connectivity, in contrast to c
261 nforces these observations and predicts that LAMP is thermodynamically stable below a critical chiAC,
263 r LAMP2 and NPC1 protein levels suggest that LAMP proteins represent a significant cholesterol bindin
268 e numerous reported techniques to detect the LAMP amplification including turbidity, bioluminescence
276 ts clinical use, the detection limits of the LAMP assay were evaluated using bacterial genomic DNA-sp
279 utive loading, mixing, and aliquoting of the LAMP primers/reagents and DNA sample solutions were acco
281 g 80 pork and milk samples revealed that the LAMP-AuNP showed 100% sensitivity, 97-100% specificity a
284 reproduced the higher mobility forms of the LAMPs, suggesting that Pompe iPSC-CMs produce LAMPs lack
285 ther African MSV isolates indicate that this LAMP assay can be used for detecting MSV in maize sample
288 ) -alkylguanine-DNA alkyltransferase) led to LAMP-to-hCG signal transduction on low-cost, commerciall
289 epidermal growth factor (EGF) trafficking to LAMP-2-positive compartments and EGF receptor degradatio
290 sputum and blood hemoculture were undergone LAMP amplification for 0.18 kbp and 0.23 kbp DNA fragmen
292 that quenched fluorescent labels on various LAMP primers can be used to quantify and detect target D
295 CpG-A shows higher co-localization with LAMP-2(+) lysosomes than CpG-B and induces DNase II loca
296 ticles (streptavidin-MNPs) are premixed with LAMP reagents including the analyte and biotinylated pri
297 full integration of sample preparation with LAMP amplification and end point detection with a limit
299 tion of mice with mouse DCs transfected with LAMP/gag (Lg-mDCs) stimulated more potent B- and T-cell