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1 LC-MS based metabolomics approach revealed that putative
2 LC-MS identified 26 compounds.
3 LC-MS identified 3090 proteoforms, including 1707 unique
4 LC-MS-based profiling of circulating angiotensin peptide
5 LC-MS/MS analyses revealed that the levels of cross-link
6 LC-MS/MS method for confirmation of nitrofuran metabolit
7 LC-MS/MS product ion scans were used to identify and sem
8 chromatography-tandem mass spectrometry (1D LC-MS/MS) workflow (i.e., from sample preparation to HCP
11 chromatography-tandem mass spectrometry (2D-LC-MS/MS) method which combines commercially available p
12 t types of bread and bakery products using a LC-MS/MS method, before and after the new European regul
13 r goals in this study were to (i) validate a LC-MS method that assesses HBP flux as UDP-GlcNAc ((13)C
14 s measurement of mAb in major tissues with a LC-MS-based method, where interesting features of mAb ti
15 chidonic acid is the predominant fatty acid, LC-MS analysis identified 2-AG as the main product of LP
16 k paves the road for implementing additional LC-MS methods to modernize testing in commercial QC with
18 njugase (rat serum and chicken pancreas) (AE-LC-MS/MS) was used in the LC-MS/MS methods, each in a si
20 AhpD variants remained partially active, and LC-MS/MS analyses revealed that the third cysteine, Cys-
21 We used plate growth and Seahorse assays and LC-MS/MS analysis to show that COQ11 deletion rescues re
24 Using immunoblotting, flow cytometry, and LC-MS-based glycolipid and glycan profiling, we found th
25 3-ols) was analyzed using GC-FID, LC-DAD and LC-MS methods, whereas the volatile compound profile was
28 ored spectrophotometrically, and by HPLC and LC-MS respectively, while antioxidant capacity was measu
30 e enzyme presented approximately 65 kDa, and LC-MS/MS allowed the identification of a polyurethanase
31 mic analysis using TMT peptide labelling and LC-MS/MS revealed that FloR is a physiological master re
33 ate measurements) from sheathless CZE-MS and LC-MS resulted in the identification of 1433 proteoforms
36 Innovative chemometric approaches by NMR and LC-MS data fusion (multiblock analysis) and decompositio
38 ocedure including the sample preparation and LC-MS/MS takes less than 55 min, enabling rapid multiatt
40 using Zeiss Zen Black microscopy systems and LC-MS protocols that are standard in many research cores
41 troscopy, and mass spectrometry (ESI-TOF and LC-MS), as well as (17)O solid state NMR (for the (17)O
42 method applied, based on rapid clean-up and LC-MS/MS determination, was previously developed and in-
44 Overall, the data generated from antibody LC-MS analyses can provide key information in early phas
45 capabilities comparable to the state-of-art LC-MS but suggest a selectivity for the detection of a d
46 ng liposome-leakage and cytotoxicity assays, LC-MS/MS-based proteomics, and CCF-4 FRET analysis, we o
47 ere, using MS-based FAHFA hydrolysis assays, LC-MS-based lipidomics analyses, and activity-based prot
48 TS platform is not compatible with automated LC-MS systems, which significantly limits sample through
50 quid chromatography-mass spectrometry-based (LC-MS-based) metabolomics, we profiled more than 1600 mo
51 (LC-MS), exhibiting a high agreement between LC-MS and MALDI-Q-MSI (Pearson correlation r = 0.87).
53 specimens from each rabbit were analyzed by LC MS/MS iTRAQ technology using an Orbitrap Fusion Lumos
55 cluding several oxidized ACs was analyzed by LC-MS in plasma and urine samples collected after the 3-
59 isolated in ~31% yield, and characterized by LC-MS, (1)H and (13)C NMR, and FT-IR methodologies, as w
60 transmethylation reactions were confirmed by LC-MS, nuclear magnetic resonance (NMR), and rationalize
62 5)N-tracers) in any metabolite detectable by LC-MS/MS and in various biological models (such as mice)
63 84 compounds identified in both genotypes by LC-MS/MS, including phenolic acids, organic acids, flavo
64 he antioxidant activities were identified by LC-MS, including phenolic acids, anthocyanins, stilbenes
65 es and determined their expression levels by LC-MS/MS using both synchronous precursor selection (SPS
66 rative data obtained demonstrate that MAM by LC-MS peptide mapping can, in principle, adequately repl
67 metabolites in the Trp catabolic pathway by LC-MS-MS in the community-based Hordaland Health Study (
70 lycolipids were identified and quantified by LC-MS and MS/MS and their profile statistically analysed
71 low (BMW) in which the same sample is run by LC-MS in both liquid chromatography solvent with (14)NH(
72 oral skeletal proteomes that we sequenced by LC-MS/MS over multiple trials in the best-preserved foss
73 ges, we developed a generic affinity capture LC-MS assay that can be utilized to evaluate the biotran
75 al and Laboratory Standards Institute (CLSI) LC-MS C62-A document and the U.S. Food and Drug Administ
76 ides (HMOs) derived from results of combined LC-MS/MS experiments and comprehensive structural analys
79 ot be identified or detected by conventional LC-MS analyses without enrichment, demonstrating the uti
83 test the performance of a recently developed LC-MS/MS method for quantification of 6 folate forms.
87 ed that PCI-IS was an accurate and efficient LC-MS/MS method to simultaneously estimate blood volume
89 ere used for the extension of an established LC-MS/MS-based method for the quantitation of several im
91 n of on-tissue MS/MS and hydrogel extraction LC-MS/MS, peptides from the enamel, dentin, periodontal
92 en compared to those obtained by the fastest LC-MS/MS method previously reported, along with a 15-fol
96 tography tandem mass spectrometry (nano-flow LC-MS/MS) is the mainstay in proteome research because o
101 in the automation of sample preparation for LC-MS analysis, a challenging next step is to fully auto
102 quires a great amount of instrument time for LC-MS data acquisition of individual digested samples, w
104 ained data correlated well with results from LC-MS/MS chemical analysis but also revealed unknown PSI
107 Research Centre (JRC) developed an improved LC-MS/MS analytical method using a pentafluorophenyl col
112 idge the inconsistencies between incongruent LC-MS metabolomics datasets of the same biological sampl
113 nd correlated with a hydrophilic interaction LC-MS/MS method for measuring plasma metanephrines (R(2)
116 d evaluate separation orthogonality in 3D LC-LC-MS separation space for all systems under investigati
117 Overall, it identified 26% of ~27 000 liver LC-MS features as putative metabolites, of which ~2600 s
118 cGTW applied to two large-scale metabolomics LC-MS datasets identifies many misaligned features and s
119 romatography tandem mass spectrometry (micro-LC-MS/MS) assay for the quantification of endogenous NPY
123 mple preparation, quantitative LC-tandem MS (LC-MS/MS) analysis, and data processing methods are prov
124 o individual metabolites generating multiple LC-MS peaks arising from isotopes, adducts, and fragment
125 graphitic carbon (PGC) columns for nanoflow LC-MS/MS analyses of native glycans released from glycop
129 oportion of the complexity and redundancy of LC-MS metabolomics data comes from adduct formation.
136 sensitivity drop in traditional ion-pairing LC-MS/MS was for the first time overcome by the introduc
137 s thaliana) for deconjugation of folates (PE-LC-MS/MS), or animal-origin deconjugase (rat serum and c
139 wer and 25% higher results was found when PE-LC-MS/MS was compared to MA and AE-LC-MS/MS, respectivel
141 transcriptomics, and ultra-high-performance LC-MS/MS- and GC/MS-based metabolomics, we found that, a
144 human AGP revealed the potential use of PGC-LC-MS for extensive glycoprotein analysis for biomarker
146 rmance, we analyzed data from reversed phase LC-MS and hydrophilic interaction chromatography (HILIC)
148 by a factor of 4-30 compared with a previous LC-MS/MS method for measuring plasma metanephrines in ou
150 gluten peptides was defined by quantitative LC-MS/MS; none were detected in the gastric phase, but r
153 n of the PhotoPPI workflow with quantitative LC-MS/MS enabled unbiased interaction mapping for the re
156 indings indicate that sensitive and reliable LC-MS/MS methods can be developed for the targeted detec
157 eveloped for the analysis of high-resolution LC-MS data for the purposes of metabolomics, but potenti
159 bing the implementation of a high-resolution LC-MS method in commercial QC laboratories for product r
160 ounds, were detected through high-resolution LC-MS/MS, among which were biomarkers of anammox bacteri
162 Here, we describe a sensitive and robust LC-MS/MS assay to quantify clinical protein biomarkers i
164 tion of untargeted high-resolution full-scan LC-MS metabolomics data remains challenging due to indiv
165 Combining protein and RNA data by searching LC-MS/MS data against a customized protein database from
166 sample preparation, an ultra-fast 84-second LC-MS method, and barcoded nanopore sequencing to rapidl
168 ysed by HPLC, combined with highly sensitive LC-MS/MS, MALDI-TOF-MS, and exoglycosidase treatments.
169 newly developed, faster, and more sensitive LC-MS/MS method to distinguish different plant-based and
175 its site-specific glycosylation in a single LC-MS/MS run and simultaneously determined the donor all
178 uid chromatography-tandem mass spectrometry (LC-MS(2)) is challenging because of the difficulties in
179 uid chromatography tandem mass spectrometry (LC-MS(2)) methods are increasingly being used in conjunc
180 Liquid chromatography-mass spectrometry (LC-MS) affords a highly promising solution for absolute
182 chromatography coupled to mass spectrometry (LC-MS) approach described in this protocol, samples in M
184 s a liquid chromatography-mass spectrometry (LC-MS) based quantification platform with high sensitivi
186 Liquid chromatography-mass spectrometry (LC-MS) delivers sensitive peptide analysis for proteomic
187 ith liquid chromatography-mass spectrometry (LC-MS) has become an essential analytical technique to q
188 Liquid chromatography-mass spectrometry (LC-MS) has been widely used throughout biotherapeutic de
189 chromatography coupled to mass spectrometry (LC-MS) is a powerful tool for characterization of ADCs.
190 Liquid chromatography-mass spectrometry (LC-MS) is a standard method for proteomics and metabolom
191 chromatography coupled to mass spectrometry (LC-MS) is emerging as a powerful tool that can provide b
192 ced liquid chromatography-mass spectrometry (LC-MS) methods with high sensitivity, accuracy and throu
193 Liquid chromatography-mass spectrometry (LC-MS) results found hallucinogenic alkaloids scopolamin
194 n a liquid chromatography-mass spectrometry (LC-MS) timescale and improve mean sequence coverage dram
195 id chromatography-coupled mass spectrometry (LC-MS) were significantly heritable under the classical
196 by liquid chromatography-mass spectrometry (LC-MS), exhibiting a high agreement between LC-MS and MA
197 romatography coupled with mass spectrometry (LC-MS), has been a powerful technique for studies of pro
198 iquid chromatography with mass spectrometry (LC-MS), which could miss detection or becomes less quant
199 and liquid chromatography-mass spectrometry (LC-MS), which despite producing more reliable results of
200 in liquid chromatography-mass spectrometry (LC-MS)-based biopharmaceutical characterization to enhan
201 ing liquid chromatography-mass spectrometry (LC-MS)-based method, has received increased attention fo
202 Liquid chromatography-mass spectrometry (LC-MS)-based proteomics approaches have been widely used
204 uid chromatography-tandem mass spectrometry (LC-MS/MS) analyses on brain homogenates of our newly gen
205 uid chromatography-tandem mass spectrometry (LC-MS/MS) analysis of ethanolic seed crude extract and f
206 uid chromatography-tandem mass spectrometry (LC-MS/MS) and deduced fractional excretion using reporte
207 uid chromatography-tandem mass spectrometry (LC-MS/MS) and liquid chromatography-multiple reaction mo
208 uid chromatography-tandem mass spectrometry (LC-MS/MS) assays were developed to measure arylsulfatase
209 uid chromatography-tandem mass spectrometry (LC-MS/MS) at atmospheric concentrations up to 50 +/- 20
210 matography coupled tandem mass spectrometry (LC-MS/MS) based metabolic profiling were utilized to dis
211 uid chromatography-tandem mass spectrometry (LC-MS/MS) enables the simultaneous quantification of num
212 uid chromatography-tandem mass spectrometry (LC-MS/MS) for clinical applications is still very challe
213 uid chromatography-tandem mass spectrometry (LC-MS/MS) has become the gold-standard technique to stud
214 uid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed and validated for the simul
215 uid chromatography tandem mass spectrometry (LC-MS/MS) highly useful in MFA due to its high sensitivi
216 uid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification of vitamins D3 and D
217 uid chromatography-tandem mass spectrometry (LC-MS/MS) method to quantify 14 antiepileptic drugs (AED
220 uid chromatography-tandem mass spectrometry (LC-MS/MS) methods, an alternative bioanalytical method w
221 ith Liquid chromatography-mass spectrometry (LC-MS/MS) proteomics data and The Cancer Genome Atlas (T
222 uid chromatography-tandem mass spectrometry (LC-MS/MS) providing information on the level of individu
223 uid chromatography-tandem mass spectrometry (LC-MS/MS) remains a significant challenge because of the
224 uid chromatography-tandem mass spectrometry (LC-MS/MS) remains an analytical challenge in large-scale
225 aphy, coupled with tandem mass spectrometry (LC-MS/MS) revealed that luteolin derivative compounds co
226 uid chromatography-tandem mass spectrometry (LC-MS/MS) to detect "twin ions" of peptides that were co
227 uid chromatography-tandem mass spectrometry (LC-MS/MS) to measure and compare PFAS levels between fir
229 uid chromatography-tandem mass spectrometry (LC-MS/MS) using both positive and negative-mode multiple
230 uid chromatography tandem mass spectrometry (LC-MS/MS) using ten-plex tandem mass tag (TMT) labeling.
232 uid chromatography-tandem mass spectrometry (LC-MS/MS) with the aid of design of experiments (DOE) ap
234 matography coupled tandem mass spectrometry (LC-MS/MS), have shown tremendous power for the parallel
238 romatography coupled with mass spectroscopy (LC-MS/MS), we detected 20 steroids within unfertilized e
239 , and accuracy while both CBS-MS/MS and SPME-LC-MS/MS methods achieved limits of quantitation below t
240 ter assay was compared to the gold standard (LC-MS/MS), showing a good correlation between both metho
243 , high-throughput, and GMP compliant subunit LC-MS method for monitoring antibody oxidation for comme
244 are collectively presented using the subunit LC-MS approach for the two molecules, and the methods sh
248 tines and conjugated acylcarnitines from the LC-MS/MS analysis of six NIST urine reference materials.
252 substrate-interacting residue, based on the LC-MS/MS data and available structural models of SrtB-su
253 rized and simultaneously correlated with the LC-MS/MS analysis of RNA modifications within the same s
256 ted a sensitive, robust, and high-throughput LC-MS/MS method to quantify vitamins D3 and D2 in serum.
262 agenesis, biochemical and biophysical tools, LC-MS/MS, and crystallographic analyses, we identified k
263 des novel information to support traditional LC-MS PFAS analyses and will greatly benefit the evaluat
265 to-noise ratios, and detection limits in ULF LC-MS-based measurements by significantly reducing chemi
269 commercial kratom products using untargeted LC-MS metabolomics, revealing two distinct chemotypes th
270 nted into sets of b- and y-ion clusters upon LC-MS/MS, which convey not only sequence information but
272 MYC in supporting cell growth, here we used LC-MS-based metabolomics to examine the metabolome of MY
274 epoint within cow across day, analyzed using LC-MS/MS techniques, and analyzed for variations across
285 raction of the water extract of tempeh using LC-MS/MS analysis and database-assisted identification.
286 reened bacterial culture media for TTX using LC-MS/MS and identified TTX-producing bacterial strains
287 by apoA-I or HDL3 in vitro and in vivo Using LC-MS/MS analysis, we analyzed the pattern of apoprotein
289 olumn reduction tandem mass spectrometry (UV-LC-MS(2)) coupled with two-stage data analysis and spike
293 teen individual BA species were measured via LC-MS/MS and total BA levels were measured using the Dia
294 -MB-468 and SUM-159PT TNBC cells, along with LC-MS/MS and HPLC metabolomics profiling, we found here
295 of the sequences (Sequence 7) combined with LC-MS/MS identified its molecular target complex, whereo
296 RAS-RAM extract was directly compatible with LC-MS/MS and no further re-extraction, evaporation or cl
298 ed sensitivity and selectivity provided with LC-MS, yielded additional site-specific information not
299 f BCA and LA ozonolysis were quantified with LC-MS as well as with the UV-vis assays for quantificati