ライフサイエンスコーパス: LCST

1 LCST events triggered by the addition of a kosmotropic s

2 e pendant acid or basic group and undergo an LCST event, the LCST event can change the bulk solution

3 ctor controlling the hydrodynamic radius and LCST.

4 e particles that maintained their size below LCST, even after removal of the harsh (high salt or pH)

5 l significance of sequence and ion-dependent LCST behavior RNA condensates have yet to be elucidated.

6 ogically active peptide repeats that exhibit LCST or UCST transitions.

7 done in removing bacterial aggregates at T > LCST (p < 0.05), exhibiting reversibility at T < LCST (p

8 ize, with larger particles exhibiting higher LCST values.

9 olvent isotope effects and of the changes in LCST with ion concentration and identity showed multiple

10 slinked poly(NIPAm) (pNIPAm), held above its LCST, formed hydrophobic cores around which shells compo

11 (p < 0.05), exhibiting reversibility at T < LCST (p < 0.05).

12 At T < LCST, the breaking force, number of unbinding events, pe

13 rse thermal stimulation to below the PNIPAAm LCST, the beads and captured streptavidin were observed

14 Our results show that magnesium ions promote LCST behavior by inducing local disorder-order transitio

15 The PIL's LCST-type transition temperature can also be influenced

16 okes radius measurements below the polymer's LCST using gel filtration chromatography.

17 ating nanoemulsions above their surfactant's LCST can instead be induced at physiological temperature

18 rings to light the presence of a second, sub-LCST transition, observed well below the LCST of oligo(e

19 This sub-LCST transition is accompanied by changes in the guest e

20 e lower critical solubilization temperature (LCST) of PNIPAM observed upon the addition of PW in the

21 ower or upper critical solution temperature (LCST and UCST, respectively) transitions in physiologica

22 have a lower critical solution temperature (LCST) above physiologic temperature, such that the mater

23 ove its lower critical solution temperature (LCST) and its release and bioactivity was measured.

24 -called lower critical solution temperature (LCST) behavior has been well-studied, there have been no

25 ibiting lower critical solution temperature (LCST) behavior, making them valuable in various applicat

26 ponsive lower critical solution temperature (LCST) copolymers, we explored the impact of composition

27 low the lower critical solution temperature (LCST) in 3 stages, in-vitro, using a novel micro-bead fo

28 with a lower critical solution temperature (LCST) in particular, are important as drug and gene deli

29 with a lower critical solution temperature (LCST) in the range of ~25-35 degrees C.

30 The lower critical solution temperature (LCST) of elastin-like polypeptides (ELPs) was investigat

31 eds the lower critical solution temperature (LCST) of PNIPAAM, micelle solutions (at >/=2.5 wt %) sha

32 ove the lower critical solution temperature (LCST) of PNIPAAm, the beads aggregate and adhere to the

33 hat the lower critical solution temperature (LCST) of PNIPAM decreased as urea was added to the solut

34 ove the lower critical solution temperature (LCST) of PNIPAM.

35 on the lower critical solution temperature (LCST) of poly( N-isopropylacrylamide) (PNiPAM) for a fix

36 on the lower critical solution temperature (LCST) of poly(N-isopropylacrylamide), PNIPAM, was invest

37 ove the lower critical solution temperature (LCST) of the polymer (approximately 30 degrees C).

38 ond the lower critical solution temperature (LCST) of the polymers used.

39 exhibit lower critical solution temperature (LCST) phase transition behavior, can exist in a coupled

40 of the lower critical solution temperature (LCST) phase transition of individual hydrogel particles

41 ersible lower critical solution temperature (LCST) phase transition.

42 at have lower-critical solution temperature (LCST) properties experience a water-like environment bel

43 to the lower critical solution temperature (LCST) properties of Pluronic F127, the particles exhibit

44 radable lower critical solution temperature (LCST) segments are applied to prepare such dynamic aggre

45 ophobic lower critical solution temperature (LCST) transition exhibited by a recombinant, stimuli-res

46 CST) or lower critical solution temperature (LCST) type of phase behavior as novel thermolytic osmoti

47 ponsive lower critical solution temperature (LCST) were created through the copolymerization of an am

48 s their lower critical solution temperature (LCST), enabling foulant removal during such temperature-

49 ove the lower critical solution temperature (LCST), PNIPAAm provides a liphophilic microenvironment w

50 low the lower critical solution temperature (LCST), resulting in a tunable release rate of the drugs

51 Below a lower critical solution temperature (LCST), they are highly soluble.

52 ibits a lower critical solution temperature (LCST)-type thermal responsive behavior.

53 ove its lower critical solution temperature (LCST).

54 ugh its lower critical solution temperature (LCST).

55 pendent lower critical solution temperature (LCST).

56 on at a lower critical solution temperature (LCST).

57 xhibits lower critical solution temperature (LCST).

58 xhibit lower critical solution temperatures (LCST) in serum above physiological temperature.

59 rimposable heat-cool cycles, we observe that LCST copolymers show clear hysteresis that varies as a f

60 The LCST behavior of ELP has been extensively studied, but t

61 The LCST phase transition originates from the interaction be

62 The LCST transition of the grafted ELP and the ELP fusion pr

63 The LCST transition results in capture of the ELP fusion pro

64 The LCST-induced dethreading of the polymer-based pseudorota

65 e aggregation behavior that occurs above the LCST and achieves precise aggregate radii when the solut

66 ng Trx-ELP/anti-Trx complex formed above the LCST could be reversibly dissociated below the LCST.

67 er, their intrinsic hydrophobicity above the LCST poses a fundamental material challenge.

68 In addition, coating above the LCST provides better cell spreading compared to coating

69 r is soluble but are less hydrated above the LCST when the polymer phase separates from solution.

70 Above the LCST, ELPs phase separate into a polymer-rich liquid, kn

71 ST but are ineffective surfactants above the LCST, resulting in emulsion fusion.

72 Increasing the temperature above the LCST, typically physiological temperatures, results in d

73 n protein onto the ELP nanopattern above the LCST.

74 es and areas of vibrational bands across the LCST transition for PNIPAM whereas NIPAM exhibits a cont

75 yl acrylamide (NIPAM) in solution across the LCST transition.

76 tic strategy of this bioconjugate allows the LCST of the material to be changed readily from a common

77 The nanoparticles (NPs) swell below the LCST and constrict above it.

78 ater nanoemulsions at temperatures below the LCST but are ineffective surfactants above the LCST, res

79 Furthermore, drug loading below the LCST of NIPAm results in roughly 2.5 times more therapeu

80 sub-LCST transition, observed well below the LCST of oligo(ethylene glycol) (OEG)-based dendrons, whe

81 xperience a water-like environment below the LCST where the polymer is soluble but are less hydrated

82 ed when the temperature is lowered below the LCST, unless the system exhibits hysteresis and forms ir

83 curring at the electrode above and below the LCST.

84 ST could be reversibly dissociated below the LCST.

85 that these substituted compounds caused the LCST of PNIPAM to rise with increasing methyl group cont

86 r basic group and undergo an LCST event, the LCST event can change the bulk solution pH.

87 Furthermore, the LCST phase transition temperature showed 100 x more unbi

88 found that there is a greater change in the LCST value between H(2)O and D(2)O for those polypeptide

89 Differences in the LCST values with heavy and light water were correlated w

90 ata which indicated that the decrease in the LCST was coupled to the direct hydrogen bonding of urea

91 e ability of a particular anion to lower the LCST generally followed the Hofmeister series, analysis

92 tion-triggered, allosteric regulation of the LCST phase transition of a polymer and are significant b

93 se they expand the available triggers of the LCST transition of stimulus-responsive polymers to bioch

94 lymer thermodiffusion in the vicinity of the LCST.

95 s released from the surface by reversing the LCST transition.

96 For coupled hydration shells, the LCST phase transition characterized by spin probing cont

97 ermore, NIR-MSI measurements reveal that the LCST value is unique for each individual hydrogel partic

98 Thus, the LCST behavior of PNiPAM involves competing roles for ion

99 The ability to allosterically trigger the LCST transition of ELPs by biomolecular recognition will

100 xy group provided a handle through which the LCST was adjusted through small-molecule quenching.

101 r in their solvent swollen state below their LCST.

102 up of the ribose sugar further modulate this LCST response.