ライフサイエンスコーパス: LPS receptor

1 (TLR4) and LPS and is a critical part of the LPS receptor.

2 nly two signalling pathways emanate from the LPS receptor.

3 R4 carbohydrates in LPS cross-linking to the LPS receptor.

4 logical activity, appears to be a functional LPS receptor.

5 a 55-kDa protein, has been identified as an LPS receptor.

6 ugh membrane CD14 (mCD14), a proinflammatory LPS receptor.

7 ike protein was previously known to bind the LPS receptor.

8 3 (polyinosinic-polycytidylic acid) or TLR4 (LPS) receptor.

9 ophages through the CD14 lipopolysaccharide (LPS) receptor.

10 fy components of the putatively shared Taxol/LPS receptor, a novel, photoactivatable Taxol analogue w

11 lthough CD14 has been identified as the main LPS receptor, accumulating evidence has suggested the po

12 We found that caspase-11, a cytosolic LPS receptor, activated the coagulation cascade.

13 n lipid A and TLR4 are essential for optimal LPS receptor activation.

14 to identify their hosts, binding first to an LPS receptor and then to a host protein.

15 receptor 4 (Tlr4) is the lipopolysaccharide (LPS) receptor and biochemical evidence that Tlr4 confers

16 eracts with ligand-binding protein and CD14 (LPS receptor) and activates expression of inflammatory g

17 formation required CD14 (a component of the LPS receptor) and NFAT.

18 the patient's monocytes expressed CD14, the LPS receptor, and bound LPS in a specific manner, but fa

19 uman neutrophils occurs via CD14, a proposed LPS receptor, and requires the presence of plasma contai

20 l. report that caspases 4/5/11 are cytosolic LPS receptors, becoming activated through oligomerizatio

21 h requires the cytosolic lipopolysaccharide (LPS) receptor caspase-11 and antagonizes IFN-I productio

22 Zanoni et al. (2017) show that the LPS receptor CD14 promotes internalization of oxidized p

23 a high affinity to monocytes but not to the LPS receptor CD14, and experiments performed at 4 degree

24 n HBP and LPS and their interaction with the LPS receptor CD14.

25 ine induction, and surface expression of the LPS receptor CD14.

26 ing expression of either lipopolysaccharide (LPS) receptor CD14 or myeloid differentiation protein-88

27 The monocyte/macrophage lipopolysaccharide (LPS) receptor CD14 was also assessed.

28 by overexpression of the lipopolysaccharide (LPS) receptors CD14 and TLR4, which antagonize each othe

29 if LPS stimulation was mediated through the LPS receptor, CD14, surface receptors on HGF were assess

30 While two LPS receptors, CD14 and CD11/CD18, have been associated

31 showed that monocytic TM interacted with the LPS receptors, CD14 and TLR4/myeloid differentiation fac

32 signaling was unrelated to the expression of LPS receptors, CD14, or toll-like receptor 4.

33 Prior to LPS-stimulation, the LPS-receptor cluster-of-differentiation 14 (CD14) and To

34 anscription factors, is the formation of the LPS receptor complex by LPS, LPS-binding protein (LBP),

35 TLR4.myeloid differentiation factor 2 (MD-2) LPS receptor complex is strongly activated by hexa-acyla

36 t that a signal transduction molecule in the LPS receptor complex may belong to the IL-1 receptor/tol

37 ding the function and biology of the corneal LPS receptor complex may lead to novel therapies for the

38 lls are capable of expressing the functional LPS receptor complex proteins, CD14 and Toll-like recept

39 The LPS receptor complex utilized by the bladder epithelial

40 ctions as the transmembrane component of the LPS receptor complex, an unduplicated pathway for the de

41 binding protein membrane CD14 to serve as an LPS receptor complex, and that LPS treatment enhances th

42 luable tools to characterize elements in the LPS receptor complex, as well as to activate or inhibit

43 ith decreased cell surface expression of the LPS receptor complex, Toll-like receptor 4 (TLR4)/MD-2.

44 omponents at the cell surface as part of the LPS receptor complex.

45 tly to each of the members of the tripartite LPS receptor complex.

46 lore its LPS binding ability and role in the LPS receptor complex.

47 e central lipid A-recognition protein in the LPS receptor complex.

48 vidual components of the lipopolysaccharide (LPS) receptor complex of proteins remain unclear.

49 uggests that the functional integrity of the LPS receptor depends both on the surface expression of a

50 Analysis of LPS receptor expression in AnxA1-null macrophages indica

51 e deletions essentially ablated soluble CD14 LPS receptor function, whereas only two of the deletions

52 deletions completely destroyed membrane CD14 LPS receptor function.

53 4 have different structural determinants for LPS receptor function.

54 imeric, truncated CD14 is a fully functional LPS receptor in both cell lines.

55 To determine the role of the CD14 LPS receptor in the pathogenic effects of naturally occu

56 ignaling molecules potentially downstream of LPS receptors in activated macrophages.

57 (TLR4) is an important lipo-polysaccharide (LPS) receptor in gastric epithelial cell signaling trans

58 receptor 4 (Tlr4) is the lipopolysaccharide (LPS) receptor in mice was reported.

59 The major monocyte/macrophage LPS receptor is the glycosylphosphatidylinositol (GPI)-a

60 The lipopolysaccharide (LPS) receptor is a multi-protein complex that consists o

61 e receptor 4 (Tlr4), the lipopolysaccharide (LPS) receptor, is sufficient to induce nuclear factor ka

62 either lacking or expressing human CD14 (the LPS receptor), it was observed that expression of human

63 smic LptD beta-taco domain that functions as LPS receptor, LptM intercalates the lateral gate of the

64 binding to the O-antigen lipopolysaccharide (LPS) receptor of Salmonella were examined at high temper

65 gest that moesin functions as an independent LPS receptor on human monocytes.

66 l half of the membrane CD14 was a functional LPS receptor on the cell membrane, we engineered a chime

67 een LPS responsiveness and the expression of LPS receptors or factors regulating LPS responsiveness o

68 colitis and in humans certain alleles of the LPS receptor protein TLR4 increase inflammatory bowel di

69 he cornea expresses functional CD14 and TLR4 LPS receptor proteins.

70 Our data, showing that LPS receptor signaling and neutralization of endogenous

71 Platelets express components of the LPS receptor-signaling complex, including TLR (TLR4), CD

72 al epithelial cells expressed the functional LPS receptor-signaling protein TLR4, which was also augm

73 fatty acid-binding protein, LPS, and soluble LPS receptor soluble CD14 (sCD14).

74 Mechanistically, Toll-like receptor 4 (TLR4, LPS receptor)-sphingosine kinase 1 (SphK1) signaling und

75 nd the activation of caspase-11, a cytosolic LPS receptor that mediates lethality in sepsis.

76 mmatory responses, such as those lacking the LPS receptor TLR4 (Toll-like receptor 4), are resistant

77 study, we investigated the importance of the LPS receptor TLR4 and MyD88, an adaptor molecule involve

78 of VEGF, NRP-1 directly interacted with the LPS receptor TLR4 and suppressed downstream signaling th

79 argeting of multiple elements, including the LPS receptor TLR4 and the key adaptor/signaling proteins

80 ry cytokines, along with upregulation of the LPS receptor TLR4 in lung tissue and increased activatio

81 velopment in mice requires activation of the LPS receptor TLR4 on the intestinal epithelium, through

82 with a global or conditional mutation of the LPS receptor TLR4 with this CMA microbiota induced expre

83 These data indicate that the LPS receptor TLR4, as well as TLR2 and CD14, do not play

84 endent IFN-beta production downstream of the LPS receptor TLR4.

85 ecific, dependent on the lipopolysaccharide (LPS) receptor TLR4, and can be recapitulated by mimickin

86 t mice, we demonstrated that the presence of LPS receptor (TLR4) is not required on hematogenous immu

87 We hypothesized that the LPS receptor (TLR4) plays a critical role in NEC develop

88 ve demonstrated that the lipopolysaccharide (LPS) receptor (TLR4) is expressed in TRPV1 containing tr

89 -driven suicide gene, we discovered that the LPS receptor Toll-like receptor 4 (TLR4) is specifically

90 culture, we demonstrate that hRetn binds the LPS receptor Toll-like receptor 4 (TLR4) through its N t

91 LPS activate caspase-11 independently of the LPS receptor Toll-like receptor 4 (TLR4).

92 at regulates signals transduced by the major LPS receptor Toll-like receptor 4 on the surface of mous

93 LPS without affecting the expression of the LPS receptor Toll-like receptor 4, demonstrating that RI

94 which acute lung inflammation depends on the LPS receptor (Toll-like receptor 4, TLR-4), the loss of

95 C3HHeJ, which has a mutation in the primary LPS receptor, Toll-like receptor 4 (TLR4), is extremely

96 Bile duct cells expressed the LPS receptor, Toll-like receptor 4 (TLR4), which links t

97 charide (LPS) requires signaling through the LPS receptor, Toll-like receptor 4 (TLR4).

98 Endotoxin-mediated down-regulation of the LPS receptor, Toll-like receptor 4, has been suggested a

99 The putative LPS receptor, Toll-like receptor 4, was expressed in THP

100 way of signaling pathways downstream of the LPS receptor, Toll-Like Receptor 4.

101 e effects were identical regardless of which LPS receptor was expressed.

102 cteria) binds to CD14 (a lipopolysaccharide (LPS) receptor) was tested.

103 s effect, the expression of CD14, the formal LPS receptor, was analyzed.

104 is the signal transduction component of the LPS receptor, whereas MD-2 is the endotoxin-binding unit