ライフサイエンスコーパス: Langerhans

1 Langerhans cell (LC) networks play key roles in immunity

2 Langerhans cell histiocytosis (LCH) and Erdheim-Chester

3 Langerhans cell histiocytosis (LCH) and the non-LCH neop

4 Langerhans cell histiocytosis (LCH) combines in one noso

5 Langerhans cell histiocytosis (LCH) is a clinically and

6 Langerhans cell histiocytosis (LCH) is a clonal disorder

7 Langerhans cell histiocytosis (LCH) is a myeloid neoplas

8 Langerhans cell histiocytosis (LCH) is a myeloproliferat

9 Langerhans cell histiocytosis (LCH) is a rare disease af

10 Langerhans cell histiocytosis (LCH) is a rare disease wi

11 Langerhans cell histiocytosis (LCH) is a rare histiocyti

12 Langerhans cell histiocytosis (LCH) is an enigmatic dise

13 Langerhans cell histiocytosis (LCH) is an inflammatory m

14 Langerhans cell histiocytosis (LCH) is an inflammatory m

15 Langerhans cell histiocytosis (LCH) is caused by clonal

16 Langerhans cell histiocytosis (LCH) is characterized by

17 Langerhans cell histiocytosis (LCH) represents a clonal

18 Langerhans cell histiocytosis (LCH)-III tested risk-adju

19 "Langerhans cell histiocytosis" (LCH) describes a spectru

20 Langerhans cells (LC) are thought to be the only mononuc

21 Langerhans cells (LC) can prime tolerogenic as well as i

22 Langerhans cells (LC) in the epidermis of patients with

23 Langerhans cells (LC), the dendritic cells of the epider

24 Langerhans cells (LCs) and CD8(+) tissue-resident memory

25 Langerhans cells (LCs) are able to orchestrate adaptive

26 Langerhans cells (LCs) are dendritic cells (DCs) localiz

27 Langerhans cells (LCs) are dendritic cells (DCs) residin

28 Langerhans cells (LCs) are epidermis-resident antigen-pr

29 Langerhans cells (LCs) are epithelial APCs that sense da

30 Langerhans cells (LCs) are professional antigen-presenti

31 Langerhans cells (LCs) are self-renewing epidermal myelo

32 Langerhans cells (LCs) are self-renewing in the steady s

33 Langerhans cells (LCs) are the dendritic cells (DCs) of

34 Langerhans cells (LCs) are the only DC subset in the hea

35 Langerhans cells (LCs) are the sole dendritic cell type

36 Langerhans cells (LCs) are the unique dendritic cells fo

37 Langerhans cells (LCs) comprise a dendritic network with

38 Langerhans cells (LCs) comprise a network of dendritic c

39 Langerhans cells (LCs) constitute a network of immune se

40 Langerhans cells (LCs) in the psoriatic epidermis engage

41 Langerhans cells (LCs) in the skin are a first line of d

42 Langerhans cells (LCs) induce type 2 antibodies reactive

43 Langerhans cells and inflammatory dendritic epidermal ce

44 Langerhans cells participate in the immune response in l

45 Langerhans cells were required for eliciting immune resp

46 Langerhans' cells (LCs) are a subset of periphery reside

47 Langerhans-type dendritic cells (LC) are the most abunda

48 Langerhans-type dendritic cells (LC) are the only type o

49 Langerhans-type dendritic cells (LC) are the only type o

50 system consists of 5 groups of diseases: (1) Langerhans-related, (2) cutaneous and mucocutaneous, and

51 After activation, Langerhans cells (LC), a distinct subpopulation of epide

52 s; CD1c), plasmacytoid DCs (pDCs; CD303) and Langerhans cells (LCs; CD1a, CD207) in uncinate tissue (

53 IL-10 production by (regulatory) T cells and Langerhans cells in regulating CHS has been established

54 particular conventional dendritic cells and Langerhans cells, accounting for the chronic inflammatio

55 utrophils, macrophages, dendritic cells, and Langerhans cells remained in the tissue at least 1 wk.

56 utrophils, macrophages, dendritic cells, and Langerhans cells, and colocalization of vaccine Ag withi

57 epithelial, monocyte-derived dendritic, and Langerhans cells via direct cell-cell transmission.

58 terstitial dendritic cells of the dermis and Langerhans cells of the epidermis, in a dose- and time-d

59 ytic conditions, Erdheim-Chester disease and Langerhans cell histiocytosis.

60 ng cancer and in Erdheim-Chester disease and Langerhans'-cell histiocytosis.

61 y an abnormality in corneal nerve fibers and Langerhans cells in patients with and without HIV-SN.

62 recurrent and systemic viral infections and Langerhans cell histiocytosis.

63 althy skin biopsies, human keratinocytes and Langerhans cells with IL-4.

64 of VIP on TLR regulation in macrophages and Langerhans cells.

65 Kupffer cells, microglia and Langerhans cells are only marginally replaced in one-yea

66 le of keratinocyte-derived cytokine TSLP and Langerhans cells (LCs).

67 dritic cells (DC) in the skin and mucosa are Langerhans cells (LC) and interstitial dermal DC (iDDC).

68 those of histiocytic human diseases, such as Langerhans cell histiocytosis.

69 R signaling licenses inflammation-associated Langerhans cell/DC to gain an enhanced capacity to promo

70 uire characteristics of psoriasis-associated Langerhans dendritic cells (DCs).

71 The development of both Langerhans cells (LCs) and microglia is highly dependent

72 The latter also included CD1a(bright) Langerhans cells.

73 diated expression of interleukin-6 (IL-6) by Langerhans cells.

74 Presentation of foreign antigen by Langerhans cells (LC) in the absence of exogenous adjuva

75 These two markers are mainly expressed by Langerhans cells, which are one of several functionally

76 ency virus type 1 (HIV-1) is internalized by Langerhans cells (LCs) in stratified epithelia and trans

77 regulates the outcome of Ag presentation by Langerhans cells (LCs) to T cells through actions on mic

78 es, highly significant reductions in CD1a(+) Langerhans cells in the dermis and CD11c(+) dermal dendr

79 CD207+ Langerhans cells (LCs) and CD11c+ myeloid dendritic cell

80 led an increased number of epidermal CD83(+) Langerhans cells in FLG-null subjects.

81 tic cells: monocyte-derived dendritic cells, Langerhans cells, and interstitial dermal dendritic cell

82 cytes, fibroblasts, melanocytes, mast cells, Langerhans cells, and Meissner's corpuscles, as well as

83 cells, dendritic cells, monocytes, NK cells, Langerhans cells, and leukocytes) had increasing mRNA ex

84 ll populations including endogenous T cells, Langerhans cells, and gammadelta T cells were not requir

85 0E) mutation-positive, refractory, childhood Langerhans cell histiocytosis (LCH) was evaluated.

86 heterogeneous diseases that mostly comprise Langerhans cell histiocytosis (LCH) and non-LCH.

87 ransit through the epidermis, which contains Langerhans cells (LC) and keratinocytes (KC), among othe

88 corneal nerve fiber tortuosity, and corneal Langerhans cell density between healthy controls and pat

89 No differences were identified in corneal Langerhans cell density (19.84 cells/mm2 for the control

90 ltrastructural features similar to cutaneous Langerhans cells (LCs).

91 mposed of classical and monocyte-derived DC, Langerhans cells, and plasmacytoid DC.

92 r with myeloid cell or with dedifferentiated Langerhans cell antigens, carry the BRAFV600E mutation.

93 talin1 regulates not only integrin-dependent Langerhans cell (LC) migration, but also MyD88-dependent

94 the effect of CHQ on human monocyte-derived Langerhans-like cells (MoLC) and dendritic cells (MoDC)

95 f langerin(high)-expressing monocyte-derived Langerhans-like cells.

96 Human CD34(+) progenitor-derived Langerhans-type dendritic cells (LCs) are more potent st

97 ection against HIV infection to skin-derived Langerhans cells in the ex vivo system, suggesting Marav

98 ify possible features that can differentiate Langerhans cells from malignant melanocytes to prevent t

99 Based on our ability to discriminate Langerhans cells (LCs), conventional DCs, monocytes, mon

100 selective expression of RUNX paralogs during Langerhans cell and inducible regulatory T cell differen

101 Epidermal Langerhans cells (eLCs) uniquely express the C-type lect

102 Epidermal Langerhans cells (LC) expressing the high-affinity recep

103 Epidermal Langerhans cells (LCs) of the skin represent the prototy

104 characterize the dermal T cell and epidermal Langerhans cell components of the skin immune system in

105 Dermal dendritic cells and epidermal Langerhans cells are APCs that migrate from skin to drai

106 ered intradermally are taken up by epidermal Langerhans cells (LCs), dermal Langerin(neg) DCs, and de

107 conventional DC subsets and not by epidermal Langerhans cells.

108 RC1 but not mTORC2 is required for epidermal Langerhans cell (LC) homeostasis.

109 oid and myeloid DCs, but also from epidermal Langerhans cells, indicating a distinct DC entity.

110 We recently reported that human epidermal Langerhans cells (LCs) are more efficient than dermal CD

111 The precise role of human epidermal Langerhans cells (LCs) in immune response is highly cont

112 henotypic characteristics of human epidermal Langerhans cells (LCs).

113 tigated the age-related changes in epidermal Langerhans cells (LCs), which play a sentinel role in th

114 ll types, including keratinocytes, epidermal Langerhans cells (LC), and dermal dendritic cells (DC).

115 ) mice contained normal numbers of epidermal Langerhans cells (eLC) and increased numbers of CD11b(+)

116 for maintaining the homeostasis of epidermal Langerhans cells (LCs).

117 upffer cells), brain (microglia), epidermis (Langerhans cells) and lung (alveolar macrophages) origin

118 Increased numbers of CD1a-expressing Langerhans cells were detected both in the epithelium an

119 g cutaneous inflammation when it facilitates Langerhans cell egress from skin and enables the accumul

120 esident member of the dendritic cell family, Langerhans cells (LCs) are generally regarded to functio

121 Unconventional immune regulatory roles for Langerhans cells, mast cells, and natural killer T (NKT)

122 plasmacytoid DC (pDC) and in vitro-generated Langerhans cells (LC) obtained from AD patients with HSV

123 enesis of 2 of the most common histiocytoses-Langerhans cell histiocytosis (LCH) and Erdheim-Chester

124 Human Langerhans cell (LC) precursors populate the epidermis e

125 s the only other cytokine expressed by human Langerhans cells.

126 nd T-helper type 1 skewing function in human Langerhans cell-like dendritic cells (LC-DCs).

127 The ontogeny of human Langerhans cells (LCs) remains poorly characterized, in

128 for all mouse DC subsets revealed that human Langerhans cells (LCs) and the mouse XCR1(+)CD8alpha(+)C

129 y factors (IRFs) as controllers of the human Langerhans cell response to epidermal cytokines was reve

130 The presence of hyperreflective Langerhans cells mimicking malignant melanocytes was the

131 ts of skin-resident DC have been identified: Langerhans cells (LCs), dermal Langerin+ DC (Lang+ dDC),

132 Following MN immunization, Langerhans cells (LCs) constituted the major skin DC sub

133 nase (ERK) signaling pathway is activated in Langerhans cell histiocytosis (LCH) histiocytes, but onl

134 eric C-type lectin specifically expressed in Langerhans cells, has been reported to be a pathogen rec

135 of skin langerin-expressing cells (including Langerhans cells).

136 NV infected a wide range of cells, including Langerhans cells, macrophages, dermal dendritic cells, m

137 most common histiocytic disorders, including Langerhans cell histiocytosis, Erdheim-Chester disease,

138 kin dendritic cell subpopulations, including Langerhans cells.

139 identify corneal nerve damage and increased Langerhans cell (LC) density in adults with Type 1 diabe

140 EP also induced Langerhans cell maturation, illustrated by CD86, CD83, a

141 Cs in SDLNs, and augmented TRITC/DBP-induced Langerhans cell (LC) migration 72 hours post TRITC treat

142 angerin and the ephrin A2 receptor to infect Langerhans cells, which support full HHV-8 lytic replica

143 DCs, including a population of inflammatory Langerhans cells.

144 al melanocyte hyperplasia and intraepidermal Langerhans cells.

145 MHD1 is also expressed in epidermis-isolated Langerhans cells (LC), but degradation of SAMHD1 does no

146 dly, huLangerin-DTA mice (DeltaLC) that lack Langerhans cells (LC) developed increased skin inflammat

147 fected HIV-susceptible CD4(+) T lymphocytes, Langerhans/dendritic cells, and macrophages.

148 of chronic inflammation, namely macrophages, Langerhans cells, myeloid-derived suppressor cells, and

149 or component of adherens junctions and marks Langerhans cells (LC), the only dendritic cell (DC) popu

150 cts with FLG-null mutations have more mature Langerhans cells in nonlesional skin irrespective of whe

151 ecause oral antigen-presenting cells (mostly Langerhans and myeloid dendritic cells) exhibit a tolero

152 Human epidermal and mucosal Langerhans cells (LCs) express the C-type lectin recepto

153 We tested the contribution of mucosal Langerhans cells (LCs) to alveolar bone homeostasis in m

154 (FLG and other skin barrier gene mutations, Langerhans cells, type 2 innate lymphoid cells, IL-33, T

155 with monocyte-derived DCs (MDDCs) and MUTZ3 Langerhans cells (LCs) to investigate their relevance as

156 Skin-resident DCs, namely, Langerhans cells (LCs), have been implicated in regulati

157 langerin (Lang; CD207)(neg) DCs, but neither Langerhans cells nor Lang(+) DCs were required for CD8(+

158 Juvenile xanthogranuloma (JXG) is a non-Langerhans histiocytic cell disorder in children which m

159 Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis that most commonly affects

160 d eruptive histiocytosis (GEH) is a rare non-Langerhans cell histiocytosis with a benign, self-healin

161 Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis, to whose pathogenesis neo

162 Rosai-Dorfman disease is a rare non-Langerhans cell histiocytosis.

163 Erdheim-Chester disease (ECD) is a rare, non-Langerhans histiocytosis.

164 In vivo studies questioned the ability of Langerhans cells (LCs) to mediate CD8(+) T cell priming.

165 lation by UVB radiation, because ablation of Langerhans cells abolished the UVB-induced phenotype.

166 e, overproduction of IFNs, and an absence of Langerhans cells.

167 ell generation in the presence or absence of Langerhans cells; analysis of BMP versus canonical TGF-b

168 matic disease defined by the accumulation of Langerhans cell-like dendritic cells (DCs).

169 oinflammatory cytokines, and accumulation of Langerhans cells and macrophages within 3 days of tamoxi

170 ations have been observed in 57% of cases of Langerhans cell histiocytosis (LCH) and 54% of cases of

171 logical heterogeneity and differentiation of Langerhans cells, delineate the signaling pathways respo

172 d TSLP and TGF-beta are potential drivers of Langerhans-like cells in vivo.

173 ology of the skin, including the function of Langerhans cells, the migration of immune cells in skin,

174 assumptions on the identity and functions of Langerhans cells (LCs) of the epidermis have undergone c

175 This infection of Langerhans cells and interstitial dermal dendritic cells

176 -derived IL-1beta alone reduced infection of Langerhans cells, macrophages, and dermal dendritic cell

177 culation led to recruitment and infection of Langerhans cells, macrophages, and dermal dendritic cell

178 ited in recent years, and the involvement of Langerhans cells (LCs), a population of epidermal dendri

179 ng beta cells within the pancreatic islet of Langerhans are responsible for maintaining glucose homeo

180 The islet of Langerhans consists of the insulin-producing beta-cells

181 egulated hormone secretion from the islet of Langerhans is central to the pathophysiology of diabetes

182 ce EXOs, we isolated cells from the islet of Langerhans of NOD mice and cultured them in vitro.

183 eleased from the alpha-cells of the islet of Langerhans, which has a key role in glucose homeostasis.

184 Macrophages in islets of Langerhans and in the interacinar stroma are distinct in

185 nly expressed on beta-cells in the islets of Langerhans and is therefore an attractive target for ima

186 tructural changes were observed in islets of Langerhans and livers of mutant animals, as well as alte

187 ecific T cells from reentering the islets of Langerhans and thereby blocked the autodestructive proce

188 The islets of Langerhans are endocrine organs characteristically dispe

189 The pancreatic islets of Langerhans are multicellular micro-organs integral to ma

190 Thus, the macrophages of the islets of Langerhans are poised to mount an immune response even a

191 Islets of Langerhans are the regulators of in vivo blood glucose l

192 xel size allows us to identify the islets of Langerhans associated with lipid isomer upregulation and

193 Also, the islets of Langerhans attracted polymorphonuclear cells, possibly v

194 s beyond the pancreatic lymph node-islets of Langerhans axis and indicates that circulating insulin,

195 Pancreatic islets of Langerhans consist of endocrine cells, primarily alpha,

196 The islets of Langerhans constitute the endocrine part of the pancreas

197 Islets of Langerhans contain antigen-presenting cells that capture

198 Human pancreatic islets of Langerhans contain five distinct endocrine cell types, e

199 from beta cells of the pancreatic islets of Langerhans controls metabolic homeostasis and is impaire

200 insulin pathway genes in isolated islets of Langerhans from these patients.

201 dynamics of multiple peptides from islets of Langerhans in a highly automated fashion is expected to

202 n Treg to prevent the rejection of islets of Langerhans in a humanized mouse model and examined the m

203 oactive spots colocalized with the islets of Langerhans in clorgyline-treated animals.

204 Insulin is secreted from the islets of Langerhans in coordinated pulses.

205 Insulin is released from the islets of Langerhans in discrete pulses that are linked to synchro

206 ncerning the lymph drainage of the islets of Langerhans in the human pancreas.

207 cells in the intestine and in the islets of Langerhans in the pancreas.

208 We found that the islets of Langerhans in young nonobese diabetic (NOD) mice contain

209 We engrafted human pancreatic islets of Langerhans into the renal subcapsular space of immunodef

210 ulin secretion from the pancreatic islets of Langerhans is enhanced by the intestinal hormone glucago

211 e endocrine pancreas, of which the islets of Langerhans is the major constituent, has been implicated

212 The spatial architecture of the islets of Langerhans is vitally important for their correct functi

213 The pancreatic islets of Langerhans maintain glucose homeostasis through insulin

214 The pancreatic islets of Langerhans maintain glucose homeostasis.

215 Encapsulation of islets of Langerhans may represent a way to transplant islets in t

216 The islets of Langerhans normally contain resident antigen presenting

217 of macrophages that reside in the islets of Langerhans of 3-wk-old non-obese diabetic (NOD), NOD.Rag

218 gen presenting cells (APCs) in the islets of Langerhans of the non-obese diabetic (NOD) mouse.

219 from pancreatic beta-cells within islets of Langerhans plays a critical role in maintaining glucose

220 Pancreatic islets of Langerhans regulate blood glucose homeostasis by the sec

221 The pancreatic islets of Langerhans regulate glucose homeostasis.

222 resident macrophages of pancreatic islets of Langerhans that lasted for several weeks.

223 ics and islet mass of transplanted islets of Langerhans throughout diet-induced progression from norm

224 What coordinates the many islets of Langerhans throughout the pancreas to produce unified os

225 , we studied the response of human islets of Langerhans upon mock or CVB3 infection.

226 et amyloid polypeptide (IAPP) from islets of Langerhans using a microfluidic system with two-color de

227 Islets of Langerhans were isolated from genetically identical 10-w

228 e problem is the reinfiltration of islets of Langerhans with regenerated, autoaggressive lymphocytes.

229 tein synthesis in freshly isolated islets of Langerhans, across a range of glucose concentrations.

230 rat pituitary, the rat pancreatic islets of Langerhans, and from the Aplysia californica nervous sys

231 se levels, preserves beta-cells in islets of Langerhans, and improves insulin action.

232 ntransparent nanoneedle arrays, of islets of Langerhans, and of hippocampal neurons under upright opt

233 bility of paracrine factors in the islets of Langerhans, and the constitution of the beta cell baseme

234 eta-cells, found in the pancreatic islets of Langerhans, are destroyed by infiltrating T cells.

235 utoreactive T-cells infiltrate the islets of Langerhans, depleting insulin-secreting beta-cells (insu

236 y dysfunction to beta-cells in the islets of Langerhans, disrupting insulin secretion and glucose hom

237 ) peptide and protein profiling of Islets of Langerhans, for future type 2 diabetes (T2D) studies.

238 nsulin-secreting beta-cells within islets of Langerhans, including their insulin secretory response a

239 A primary insult to the pancreatic islets of Langerhans, leading to the activation of innate immunity

240 ocrine compartment, organized into islets of Langerhans, produces hormones that regulate blood glucos

241 cells were directly recruited into islets of Langerhans, where they established contact with resident

242 s from small tissue depots such as islets of Langerhans, which are required for the proper control of

243 rne factors dynamically access the islets of Langerhans.

244 nsulin-producing beta cells in the islets of Langerhans.

245 f the transporter localized in the islets of Langerhans.

246 usters of the type found in normal islets of Langerhans.

247 ecreting cells and isolated rodent islets of Langerhans.

248 population of nonbeta cells in the islets of Langerhans.

249 ne cell activity in the pancreatic islets of Langerhans.

250 pancreas and complete loss of the islets of Langerhans.

251 restricted microenvironment of the islets of Langerhans.

252 ly dilated secretory ducts without islets of Langerhans.

253 of insulin-producing beta cells in islets of Langerhans.

254 multiple micro-organs known as the islets of Langerhans.

255 insulin secretion dynamics of the islets of Langerhans.

256 ed in pancreatic insulin-producing islets of Langerhans.

257 autoaggressive lymphocytes to the islets of Langerhans.

258 in the extracellular space of the islets of Langerhans.

259 angerin, the distinguishing C-type lectin of Langerhans cells, would recognize the highly mannosylate

260 ells and specifically increased the level of Langerhans cells activation.

261 pids, whereas DHA abrogated the migration of Langerhans cells, as assessed by immunohistochemistry.

262 ts internalization in specific organelles of Langerhans cells.

263 s (LCH) represents a clonal proliferation of Langerhans cells.

264 dent manner, suggesting an essential role of Langerhans cells and dendritic cells in CHQ-provoked pso

265 There is little data on treatment of Langerhans cell histiocytosis (LCH) in adults.

266 ing molecule that is abundantly expressed on Langerhans cells.

267 interplay of the C-type lectins, Langerin on Langerhans cells (LCs), and dendritic cell-specific inte

268 Langerin, a C-type lectin on Langerhans cells, mediates carbohydrate-dependent uptake

269 Langerin is a C-type lectin present on Langerhans cells that mediates capture of pathogens in a

270 n the cohort with Erdheim-Chester disease or Langerhans'-cell histiocytosis, the response rate was 43

271 migratory dendritic cells and in particular Langerhans cells at governing T follicular helper and ge

272 Precursors of pathological Langerhans cells have yet to be defined.

273 tion of the epidermal mononuclear phagocytes Langerhans cells (LCs) to this phenomenon because of the

274 atients with refractory, risk-organ-positive Langerhans cell histiocytosis (LCH) in 2005.

275 Antigen-presenting Langerhans cells show a differential migration phenotype

276 Activation via RANKL prevents Langerhans cell apoptosis, thus leading to enhanced anti

277 ells from BM of MS-RO+ LCH patients produced Langerhans cell (LC)-like cells in vitro.

278 hough lymphangioleiomyomatosis and pulmonary Langerhans cell histiocytosis are perhaps more frequentl

279 us on lymphangioleiomyomatosis and pulmonary Langerhans cell histiocytosis.

280 stinct types in the skin: branched, putative Langerhans cells, and amoeboid cells.

281 is functional, resulting in slightly reduced Langerhans cell numbers.

282 However, Flt3L-dependent DCs and resident Langerhans cells are dispensable for the inflammation.

283 could be detected in the epidermal-resident Langerhans cells (LCs) as mRNA and protein.

284 However, the roles of skin-resident Langerhans cells (LCs) in eliciting immune responses hav

285 s highly expressed by DC purified from skin (Langerhans cells) and bone marrow, and has been shown to

286 At steady state, Langerhans cells (LCs) were lineage traced but also expr

287 dermally delivered TLR agonists to stimulate Langerhans cells and dermal DCs in their natural complex

288 his issue, Su and Igyarto (2019) showed that Langerhans cells (LCs) obtain mRNA from keratinocytes (K

289 cific pattern recognition receptor TLR7, the Langerhans cell chemoattractant CCL20, and proinflammato

290 isrupted, allowing easier access of HIV-1 to Langerhans cells (LC) in the epidermis and perhaps even

291 uman immunodeficiency virus-1) transmission, Langerhans cells of genital mucosa play a protective rol

292 Strikingly, using Langerhans cells model systems (mutz-3-derived LC, monoc

293 dressed this in human ex vivo skin, in vitro Langerhans cells, and IDEC models generated from primary

294 novel somatic ARAF mutation in a child with Langerhans cell histiocytosis (LCH) and demonstrate that

295 of two humans from skeletal collections with Langerhans Cell Histiocytosis (LCH), a benign osteolytic

296 During infection, HPV16 also interacts with Langerhans cells (LC), the APC of the epithelium, induci

297 facilitate the interaction of M. leprae with Langerhans cells.

298 9 patients with ECD and ECD overlapping with Langerhans cell histiocytosis (so-called mixed histiocyt

299 have been observed in half of patients with Langerhans cell histiocytosis (LCH) and in 50% to 100% o

300 ing data to date on a group of patients with Langerhans cell histiocytosis (LCH), which historically