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1 tuberculosis complex, namely M. microti and M. africanum.
2 ng lineage, the Euro-American X lineage, and M. africanum.
3 s M. tuberculosis, 6 (1%) were identified as M. africanum, 8 (1%) were identified as M. bovis, and 13
4 T-6 and CFP-10, comparing M. tuberculosis to M. africanum and a strain of M. africanum complemented w
5 nd IFN-alphabeta receptor knockout mice with M. africanum and monitored bacterial growth, lung diseas
6 TB complex (354 cases of M. tuberculosis, 20 M. africanum and one case of M. bovis) and 69 (15%) were
7 ion apparatus member, Rv3879c, is mutated in M. africanum, and individuals infected with M. africanum
8 comprising species such as M. tuberculosis, M. africanum, and M. canettii, is the causative agent of
10 However, there is no simple definition of M. africanum, and some authors question the validity of
11 ally identified as M. bovis were shown to be M. africanum because they had a wild-type pncA sequence
12 l identifications for all TBC members except M. africanum, but further characterization resulted in p
13 an isolates from Sierra Leone, identified as M. africanum by biochemical and growth characteristics.
14 all strains, although these were enriched in M. africanum cell lysates, suggesting a modest ESX-1 sec
15 tuberculosis to M. africanum and a strain of M. africanum complemented with M. tuberculosis Rv3879c.
17 Genotypic analyses identified a cluster (M. africanum group A) which included M. africanumT and w
18 These results confirm impaired fitness of M. africanum in vivo and indicate that Rv3879c is not re
19 t IFN-alphabeta is pathogenic during chronic M. africanum infection and that the pathogenic effects m
24 deletion, specific to the animal-adapted and M. africanum L6 lineages, that restores ESAT-6 secretion
25 M. africanum, and individuals infected with M. africanum less frequently demonstrate T-cell response
26 tuberculosis complex (TBC; M. tuberculosis, M. africanum, M. canettii, M. microti, M. bovis, and M.
27 of M. tuberculosis, M. bovis, M. bovis BCG, M. africanum, M. microti, and M. canettii was developed.
28 l-characterized isolates of M. tuberculosis, M. africanum, M. microti, M. bovis, and M. bovis BCG.
29 r-positive pulmonary tuberculosis exposed to M. africanum progress less frequently to active disease
32 isingly, coincident polymorphisms linked one M. africanum subtype I genotype with the dassie bacillus
33 . tuberculosis (or M. africanum subtype II), M. africanum subtype I, M. bovis, M. bovis BCG, M. capra
34 ther as MtbC composed of M. tuberculosis (or M. africanum subtype II), M. africanum subtype I, M. bov