ライフサイエンスコーパス: MEM

1 MEM accounts for the absorption and emission of photons

2 MEM analyses showed that no significant differences exis

3 MEM enabled high-throughput characterization of microbia

4 MEM estimates are valuable for study planning; we used s

5 MEM explants treated with either inhibitor demonstrated

6 MEM is not suitable for the modeling of CEC data because

7 MEM opens a path for the microbiome field to acquire dee

8 MEM outperforms traditional metrics in describing immune

9 MEM provides a quantitative language to communicate char

10 MEM results were superior overall with confidence interv

11 MEM treatment also significantly decreased elevated vitr

12 MEM-18 and 61D3 (anti-CD14 mAbs) were poor inhibitors of

13 the negative-control groups (Ng-rPorB, 13%; MEM-0, 19%; P < 0.05).

14 Among these compounds, 17, with a C-28 MEM ester moiety, and 22, with a C-28 ethyl hexanoate, i

15 ms were visualized by CLSM on 46 (92%) of 50 MEM specimens from children with OME and recurrent OM us

16 es is not greater than a minimum length of a MEM.

17 erative search algorithms" is refuted with a MEM analysis of their triexponential test case with incr

18 baseline cognitive composite scores of ADNI-MEM and ADNI-EF, (2) identifying subjects with significa

19 MPA concentrations other than 1:320 and all MEM-based tests had suboptimal sensitivities or specific

20 on of SPBN-TNF-alpha+ than of SPBN-TNF-alpha(MEM) or SPBN-TNF-alpha-, which carries an inactivated TN

21 ble membrane-bound TNF-alpha [SPBN-TNF-alpha(MEM)].

22 ow perfusion bioreactor system wherein alpha-MEM (supplemented with 10% fetal bovine serum and 1% ant

23 ow perfusion bioreactor system wherein alpha-MEM (supplemented with 10% fetal bovine serum and 1% ant

24 ATT-C and MEM-C scores were developed by averaging z-scores based

25 Similar to the calpain and MEM domains, the Linker is highly conserved in the land

26 may determine the magnitude of both EFFE and MEM cells, which arise subsequently.

27 We isolated NAI, EFFE, and MEM CD8(+) T cell subsets from human peripheral blood an

28 s that strongly differentiate NAI, EFFE, and MEM CD8(+) T cells; these genes provide previously unrec

29 rs the development of adaptive immunity, and MEM is incomplete.

30 Hodge test (MHT) was performed using IPM and MEM disks.

31 ithelial stem/progenitor cells of the TM and MEM in quantity for large-scale analyses and will enhanc

32 deed, our data show that the expanded TM and MEM stem/progenitor cells respond to Ca(2+) stimulation

33 pts are illustrated using kinetic traces and MEM populations derived from the CO recombination proces

34 The LFA-1 activating antibody MEM-83, or its Fab fragment, decreased the rolling veloc

35 Monoclonal antibody MEM-265 recognizes the peptide-free conformation of the

36 The absence of a B(MEM) response to nonspecific inflammatory signals clearl

37 Memory B (B(MEM)) cells and long-lived bone marrow plasma cells (BM-

38 nflammatory signals promote memory B cell (B(MEM)) self-renewal and differentiation in an antigen-ind

39 B cell markers before generating daughter B(MEM) and differentiating into plasma cells or form struc

40 onse profiles of B-2 lineage B220(+)IgG(+) B(MEM) toward cognate protein antigen in comparison to bys

41 We report herein that long-lived B(MEM) cell survival and function are completely independe

42 tander proliferation or differentiation of B(MEM) occurred.

43 ivation, fail to induce even low levels of B(MEM) proliferation or differentiation in vivo.

44 Surprisingly, proliferating B(MEM) do not acquire germinal center (GC) B cell markers

45 After in vivo antigen encounter, quiescent B(MEM) clonally expand.

46 However, the factors supporting B(MEM) cell survival within the secondary lymphoid organs

47 ic inflammatory signals clearly shows that B(MEM) proliferation and differentiation is a process tigh

48 Thus, B(MEM) cells represent the only mature B2 lineage subset w

49 ers and decliners did not differ on baseline MEM scores, but maintainers did have higher non-MEM cogn

50 taxa had no significant differences between MEM-treated and untreated control groups).

51 d BG alone, and Group 2, which received BG + MEM.

52 of random noise had similar effects on both MEM and NLLS results.

53 ations in SeqLib: HTSlib for BAM access, BWA-MEM and BLAT for sequence alignment and Fermi for error

54 hree general-purpose short-read aligners-BWA-MEM, Bowtie 2, and Arioc-in conjunction with three germl

55 ing combinations of three read aligners--BWA-MEM, Bowtie2, and Novoalign--and four variant callers--G

56 Chromap is comparable to BWA-MEM and Bowtie2 in alignment accuracy and is over 10 tim

57 neral-purpose short-read alignment tools-BWA-MEM, Bowtie 2 and Arioc-with a focus on performance opti

58 Notably, a single pipeline using BWA-MEM and GATK-HaplotypeCaller performed comparable to the

59 ose produced by alignments created using BWA-MEM to a linear-reference and Giraffe mapping to a pange

60 ads from a CRAM file and then align with BWA-MEM.

61 on of I-GPI cells with ICAM-3 was blocked by MEM-83.

62 may accurately automate driver detection by MEM and add some objectivity to the interpretation of ME

63 D52 expression at mRNA level was observed by MEM treatment in CWR22Rv1 and C(4-2) cells in a dose-dep

64 -67 as essential for specific recognition by MEM-265.

65 onent in the antigenic epitope recognized by MEM-265 in the peptide-free form of major histocompatibi

66 rrors in lifetime distributions recovered by MEM was compared to that in standard nonlinear least-squ

67 ements, on fluorescence lifetime recovery by MEM.

68 concentrations in tap water and calculating MEM confidence intervals for the true, latent signal mea

69 ntaining gel alone implanted over calvarium (MEM-GEL; n = 10); 4) implanted PLA membrane containing g

70 th sPGN and ReLPS was inhibited by anti-CD14 MEM-18 mAb, but other anti-CD14 mAbs showed differential

71 Chronic MEM treatment significantly improved retinal function an

72 ated slopes of an episodic memory composite (MEM) to classify them into two groups: maintainers (slop

73 the neuroprotective effect of this compound, MEM can reduce vascular changes seen in diabetic retinas

74 Biofilms were not observed on 8 control MEM specimens obtained from the patients undergoing coch

75 Uninfected (control) MEM specimens were obtained from 3 children and 5 adults

76 e is regulated by the membrane-anchored DEK1 MEM, which is connected to the calpain via the 600-amino

77 and DEK1 calpains, we propose that the DEK1 MEM-Linker complex inactivates the calpain by forcing ap

78 Arabidopsis thaliana dek1 mutants, and DEK1-MEM also failed to restore wild-type phenotypes in Arabi

79 Instead, ectopic expression of DEK1-MEM under the control of the cauliflower mosaic virus 35

80 consists of a membrane-spanning region (DEK1-MEM) and a calpain-like Cys proteinase region (DEK1-CALP

81 gher density but only 80% with lower-density MEM arrays (81% for lower-density+higher-density arrays

82 Since DEX, MEM and KET are currently used in humans and considered

83 nd consists of a large transmembrane domain (MEM) linked to a protease catalytic domain and a regulat

84 vested and cultured for three days in either MEM or MEM plus 10% serum.

85 NIOM; 0.3 mm(2) resolution) and 64-electrode MEM (higher density or lower density with 3 and 9 mm(2)

86 -52 and Gln-64, that contribute by enhancing MEM-265 binding.

87 To evaluate MEM performance and compare with widely used depth weigh

88 BMD reproducibility was 95% for MEM and MIN only, and MicroScan WalkAway reproducibility

89 a and 46a could be prepared analogously from MEM ether 44c, but the sensitivity of several of the int

90 microscopic (CLSM) images were obtained from MEM biopsy specimens and were evaluated for biofilm morp

91 Bioinformatic analysis identifies MEM as a member of the Major Facilitator Superfamily, me

92 white rats (Sprague-Dawley) were cultured in MEM enriched with 5% horse serum.

93 ns for driver versus nondriver electrodes in MEM arrays.

94 terial OM via the activation of Erk1/Erk2 in MEM of an in vivo rat bacterial OM model.

95 Human gingival fibroblasts were incubated in MEM containing chlorhexidine concentrations ranging from

96 The arterial segments were incubated in MEM for 24 hours at 37 degrees C in the presence or abse

97 assessed whether this pathway is involved in MEM hyperplasia during bacterial OM via the activation o

98 support a role for Ras and Erk signaling in MEM hyperplasia during bacterial OM.

99 ted with increasing titers of the vectors in MEM.

100 dicate that FL tumors can be classified into MEM-like and GC-like subtypes that are biologically dist

101 e predictor (FL20) to classify patients into MEM-like (n = 160) or GC-like (n = 164) subtypes, which

102 as 93%, 98%, 99%, 98%, and 96% for CAZ, LVX, MEM, MIN, and TMP-SMX, respectively.

103 llel to those recognized by anti-HLA-E mAbs (MEM-E/02/06/07).

104 linical surface-only multielectrode mapping (MEM) has relied on subjective interpretation of activati

105 ign of future vaccine strategies to maximize MEM cell generation.

106 (EEG/MEG): the Maximum Entropy on the Mean (MEM), to solve the inverse problem of DOT reconstruction

107 sue culture milieu, Minimum Essential Media (MEM), the sensitivity of the EIS measurement was greater

108 i.n. with Eagle's minimal essential medium (MEM-0).

109 ll culture medium (minimum essential medium, MEM) and fetal calf serum (FCS) were probed by XANES and

110 To test whether chronic memantine (MEM) treatment improves retinal function and prevents ne

111 o memantine, or NTX (50 mg/day) + memantine (MEM; 20 mg/day), during the first treatment period, foll

112 her 5 mM dextrorphan (DEX), 10 mM memantine (MEM) or 10 mM ketamine (KET) significantly attenuated fo

113 without a non-crosslinked collagen membrane (MEM).

114 AI) T cells into effector (EFFE) and memory (MEM) cells is incompletely understood.

115 Immunological memory (MEM) development is affected by stress-induced neuroendo

116 signatures (GSs) enriched in normal memory (MEM) B cells and germinal center (GC) B-cell signals, re

117 axone (CRO), ertapenem (ETP), and meropenem (MEM) and demonstrate agreement with gold-standard AST.

118 henicol (CAM), ceftazidime (CAZ), meropenem (MEM), trimethoprim-sulfamethoxazole (TMP-SMX), minocycli

119 the beta-lactams imipenem (IPM), meropenem (MEM), ertapenem (ERT), and ceftazidime (CAZ).

120 Imipenem (IPM), meropenem (MEM), ertapenem (ERT), and doripenem (DOR) were tested b

121 zidime (CAZ), levofloxacin (LVX), meropenem (MEM), minocycline (MIN), and trimethoprim-sulfamethoxazo

122 e we describe a microbial-enrichment method (MEM), which we demonstrate on a wide range of sample typ

123 A maximum entropy method (MEM) analysis was performed on the single-crystal X-ray

124 The maximum entropy method (MEM) further chooses a unique model from the group of fe

125 The maximum entropy method (MEM) has been used in many studies to reliably recover e

126 The maximum entropy method (MEM) is used to numerically invert the kinetics of ligan

127 The maximum entropy method (MEM) provides a robust and unbiased solution to fluoresc

128 is that combines the maximum entropy method (MEM) with nonlinear least squares (NLS) fitting has been

129 ferent ratios of the regioisomeric pairs MME/MEM, PPE/PEP, PPD/PDP, EEP/EPE and DDP/DPD (M=14:0, P=16

130 A mixed-effects model (MEM) and a pointwise VF progression analysis of pattern

131 dent samples, and a Measurement Error Model (MEM) approach in a random effects analysis of variance (

132 We present marker enrichment modeling (MEM), an algorithm that objectively describes cells by q

133 ates obtained from master equation modeling (MEM), using the water binding energy as a fit parameter.

134 op individual-based movement ecology models (MEM) to explore turkey vulture (Cathartes aura) migratio

135 ucing reagent for acyclic acetal (i.e., MOM, MEM, SEM, and BOM) protected alpha-hydroxy ketones.

136 N, SETTING, AND PATIENTS: Middle-ear mucosa (MEM) biopsy specimens were obtained from 26 children (me

137 Hyperplasia of middle-ear mucosa (MEM) during otitis media (OM) is thought to be partially

138 nic membrane (TM) and the middle ear mucosa (MEM).

139 The middle ear muscle (MEM) reflex is one of two major descending systems to th

140 Compared to NLLS, MEM afforded significant improvements for the recovery o

141 scores, but maintainers did have higher non-MEM cognitive scores.

142 ly, when NTX + MEM followed NTX alone, NTX + MEM resulted in a further reduction in drinking (mean: -

143 Individually, both NTX and NTX + MEM, when compared to BAS ADP1, significantly reduced th

144 When comparing NTX + MEM vs. NTX on number of drinks consumed, there was a si

145 However, when NTX alone followed NTX + MEM, NTX alone did not lead to further reduction in drin

146 reduction in craving was observed when NTX + MEM followed NTX alone (p = 0.009), but craving reductio

147 Specifically, when NTX + MEM followed NTX alone, NTX + MEM resulted in a further

148 craving reduction was maintained when NTX + MEM was followed by NTX alone.

149 aimed to explore the mechanism of action of MEM in prostate cancer (PCa) by employing an in vitro gl

150 ed to the dynamic, self-modeling approach of MEM and the direction provided by the entropy criterion.

151 This effect of MEM was not seen in nondiabetic rats.

152 to identify the vasculoprotective effect of MEM.

153 n after treatment with methanolic extract of MEM.

154 v1after treatment with methanolic extract of MEM.

155 Intraperitoneal injection of MEM considerably slowed tumor growth in athymic mice, in

156 dd some objectivity to the interpretation of MEM findings.

157 nd effected genes to define the mechanism of MEM action in prostate cancer.

158 his article is to (a) provide an overview of MEM reflex anatomy and physiology, (b) present new data

159 Shotgun sequencing of MEM-treated human intestinal biopsies enabled characteri

160 oderate proliferative response above that of MEM (P < 0.001).

161 Control cells received an equal volume of MEM without chlorhexidine for similar times at 37 degree

162 Direct detection of biofilms on MEM biopsy specimens from children with OME and recurren

163 tomy and physiology, (b) present new data on MEM reflex anatomy and physiology from our laboratory an

164 en comparing the accuracy of DD to BMD, only MEM met all acceptance criteria.

165 um Essential Medium (Opti-MEM-I) alone; Opti-MEM-I plus EGF, NGF, PDGF-BB, bovine pituitary extract,

166 lular uptake profiles were evaluated in Opti-MEM and demonstrate that all the click clusters efficien

167 ified Eagle's Minimum Essential Medium (Opti-MEM-I) alone; Opti-MEM-I plus EGF, NGF, PDGF-BB, bovine

168 d growth in an artificial serum medium, Opti-MEM, and a rich LB-based medium with Na(+) levels and pH

169 less IFU than the Ng-rPorB (40 x 10(6))- or MEM-0 (70 x 10(6))-immunized mice (P < 0.05).

170 ncurrently differentiate into either EFFE or MEM cells (parallel differentiation) remains unresolved.

171 diate state followed by a split into EFFE or MEM cells, hence supporting the parallel differentiation

172 and cultured for three days in either MEM or MEM plus 10% serum.

173 roving the temporal accuracy of the original MEM framework.

174 Our results showed that overall MEM provided more accurate DOT reconstructions than MNE.

175 Additionally, an in vitro model of rat MEM in bacterial OM was treated with farnesyl transferas

176 substitutions that either improve or reduce MEM-265 recognition could be traced to differences in th

177 ent claims made by Mulligan et al. regarding MEM analyses of kinetics are shown to be unfounded.

178 Maytenus roylanus (MEM) is a plant with anti-proliferative effects against

179 + IL-1 respectively for 24 hours in Eagle's MEM at 37 degrees C.

180 aset curation and feature extraction, SAAMBE-MEM was trained and validated using the XGBoost regressi

181 A novel sequence-based method (SAAMBE-MEM) for predicting binding free energy changes (DeltaDe

182 Furthermore, it was demonstrated that SAAMBE-MEM performs much better when utilizing evolution-based

183 ore (ATT-C), and a memory composite z-score (MEM-C).

184 SDR-MEM mice had significantly attenuated anti-influenza IgG

185 b)NP(366-74)CD8(+) T cell populations in SDR-MEM mice.

186 Moreover, during resting memory, SDR-MEM mice responded with an enhanced footpad delayed-type

187 were rechallenged with A/PR/8/34 virus, SDR-MEM mice terminated viral gene expression significantly

188 ells were starved in 0.1% fetal bovine serum/MEM for 72 h and then treated with 50-450 microM caffein

189 PLA membrane containing gel and simvastatin (MEM-SIM; n = 10); and 5) untreated mice (n = 12).

190 actors in fate determination of T(EFF) and T(MEM) cells using in vivo pooled CRISPR screening, focusi

191 context-dependent T(EFF) proliferation and T(MEM) development.

192 cell (T(EFF)) subsets tune memory T cell (T(MEM)) responses remains incompletely understood.

193 te into functional durable memory T cells (T(MEM)) upon antigen clearance.

194 subdivide circulating and non-circulating T(MEM) cell subsets, and govern terminal differentiation.

195 enes were poised in T(N), but activated in T(MEM) or T(EX) whereas other genes poised in T(N) were re

196 her genes poised in T(N) were repressed in T(MEM) or T(EX), indicating that both repression and activ

197 of distinct effector (T(EFF) ) and memory (T(MEM) ) CD8 T cell subsets.

198 Compared to memory (T(MEM)) cells, T(EX) have a unique open chromatin landscap

199 modifications in naive CD8 T cells (T(N)), T(MEM) and T(EX).

200 ted super-enhancers that distinguish T(N), T(MEM) and T(EX), along with key transcription factor netw

201 phenotypic and transcriptional features of T(MEM) cells.

202 c7a1 and Slc38a2 dampened the magnitude of T(MEM) differentiation, in part through modulating mTORC1

203 eening, focusing on negative regulators of T(MEM) responses.

204 fate and shape the quantity and quality of T(MEM) responses.

205 ing CD4(+) T(EFF) cells or in reactivating T(MEM) cells in vitro, whereas cDC2 retained moderate stim

206 cells remained compromised as compared to T(MEM) cells.

207 e expression programs of T(EX) compared to T(MEM) through both activating and repressive pathways.

208 l gene expression significantly earlier than MEM mice and generated a greater D(b)NP(366-74)CD8(+) T

209 Moreover, we found that MEM was remained particularly robust in low signal-to-no

210 These results indicate that MEM could be useful for the treatment of ocular diseases

211 nships between these subsets and showed that MEM cells have gene expression patterns intermediate bet

212 The results showed that MEM provided more accurate HbO and HbR reconstructions i

213 imates a 3.5-residue repeat, suggesting that MEM-265 may recognize the epitope in an alpha-helical co

214 The MEM approach also featured an unparalleled advantage in

215 The MEM approach describes the data much better than traditi

216 The MEM approaches generated size-standardized concentration

217 The MEM confirmed that uveitic eyes (-0.49 dB/year) showed h

218 The MEM reflex pathways begin with sound presented to the ea

219 The MEM resolves two barrier distributions suggestive of reb

220 the stem/progenitor cells of the TM and the MEM epithelia remains largely uncharacterized due, in pa

221 lial stem/progenitor cells of the TM and the MEM while avoiding their malignant transformation.

222 ether and the t-alcohol functionality as the MEM ether to give 20, which after sequential reduction/o

223 ation of the parameter space achieved by the MEM stabilizes the introduction of each successive expon

224 We suggest how the MEM can be extended to other spatial and temporal scales

225 Revision of the MEM "prior" based on features in the data can improve th

226 show that the postulated sensory Loop of the MEM domain plays an important role in the developmental

227 We also proposed a new initialization of the MEM model improving the temporal accuracy of the origina

228 recovered from noisy kinetics data with the MEM can be improved by using a simple filter when bootst

229 distribution of lifetimes obtained with the MEM.

230 troduced depth weighting strategy within the MEM framework for DOT reconstruction to avoid biasing th

231 ls serially differentiate into EFFE and then MEM cells (linear differentiation) or whether they concu

232 These MEM estimates were approximately unbiased on average wit

233 Herein we compare SERs to three MEM approaches; restricted maximum likelihood, Bayesian

234 6 to an alanine actually improved binding to MEM-265.

235 eus project either directly or indirectly to MEM motoneurons located elsewhere in the brainstem.

236 Unipolar MEM and NIOM recordings were processed by Fourier transf

237 on with 1 x 10(4.5) PFU of influenza A virus MEM H3N2, followed by intranasal challenge with 5 x 10(7

238 We show that the multiple-well MEM approach described here yields superior results in s

239 Both single-well and multiple-well MEM approaches are used.

240 rty-one percent (n = 221) of the cohort were MEM maintainers, and 33% (n = 105) of decliners converte

241 the thickest point of calvarial bone, while MEM-SIM caused a highly significant (P < or = 0.0005) in

242 lar recombination traces in conjunction with MEM (maximum entropy method) analysis of kinetic populat

243 e treated either with the second VEH or with MEM (10 mg/kg daily) for another 3 to 4 weeks using mini

244 has a benefit over R-chemo for patients with MEM-like FL (HR, 0.54; P = .011).

245 In the R-chemo arm, patients with MEM-like FL had significantly shorter progression-free s

246 clinical practice to identify patients with MEM-like FL who might benefit from therapies other than

247 media were removed, cells washed twice with MEM supplemented with 10% FBS, and fibroblasts in treatm