ライフサイエンスコーパス: MIT

1 MIT contains two duplicated 6- or 7-amino acid motifs wi

2 MIT differed among treatment groups (P=.009), showing an

3 MIT helices alpha2 and alpha3 recognize a (D/E)xxLxxRLxx

4 MIT-MIM2 interactions appear to be common throughout the

5 xR198'L199'xxL202'R203', identical to type 1 MIT-interacting motif (MIM1) (D/E)xxLxxRLxxL(K/R) of CHM

6 ESCRT-III proteins) through canonical type 1 MIT-interacting motif (MIM1) interactions.

7 : standard care only, 192; prayer only, 182; MIT therapy only, 185; and both prayer and MIT therapy,

8 e pyrochlore Cd2Os2O7 nonetheless exhibits a MIT entwined with magnetic order phenomenologically simi

9 nding region of Vta1 unexpectedly revealed a MIT-like region.

10 nic and magnetic phases are separated across MIT which appears compelling for bulk systems has been e

11 T(3) formation involves coupling between an MIT donor and a DIT acceptor.

12 MHz HTS insert, while another version for an MIT 1-GHz microcoil NMR magnet whose small-scale model w

13 The presence of an MIT and the accompanying atypical electronic characteris

14 ing edge of migrating cells and show that an MIT complex drives these protrusions.

15 The application is released under an MIT licence and can be deployed on any server running Li

16 mplemented in Java 1.8 and released under an MIT licence.

17 All code is released under an MIT licence.

18 The application is distributed under an MIT license.

19 3 and Javascript, and is maintained under an MIT license.

20 2 analysis software are distributed under an MIT open-source license.

21 he tensile strained film, which undergoes an MIT, but is absent in the compressively strained film.

22 It is publicly available with an MIT license at github.com/optimusmoose/jsms.

23 ere differentially expressed between ATH and MIT, including 443 that were up-regulated and 373 that w

24 s or no off-site prayer (double-blinded) and MIT therapy or none (unmasked).

25 igher dosages, the effects of ethonafide and MIT on EAE were identical, whereas in lower dosages, MIT

26 ng data from 68 MOOCs offered by Harvard and MIT between 2012 and 2014, we found that course particip

27 ith neuroimaging laboratories at Harvard and MIT.

28 atform at the Broad Institute of Harvard and MIT.

29 unction, which was prevented by both HIT and MIT.

30 l gradient across the parasite membrane, and MIT is a prototype for understanding the function of an

31 support a model wherein a network of MIT and MIT-like domain interactions with ESCRT-III subunits con

32 ; MIT therapy only, 185; and both prayer and MIT therapy, 189.

33 H. bilis, H. mastomyrinus, H. rodentium, and MIT 96-1001 was also encountered, as were mice infected

34 shed that Sp1 is a critical target of TA and MIT in human pancreatic cancer therapy, rationalizing cl

35 bacter canis, Helicobacter winghamensis, and MIT 99-5504).

36 on the oocyte surface at a similar level as MIT wild type, confirming that these mutations affect tr

37 prayer and 377 no prayer; 374 were assigned MIT therapy and 374 no MIT therapy.

38 ), thus advancing/suppressing the associated MIT.

39 ade in facilitating our research programs at MIT and later at Caltech.

40 Then, in 1964, a graduate student at MIT discovered the power of sodium dodecyl sulfate (SDS)

41 There was a significant correlation between MIT and II in those who had acute rejection in the late

42 hway partners, with CHMP1-3 proteins binding MIT domain-containing proteins, such as VPS4 and Vta1/LI

43 on revealed that structural features in both MIT and MIM contribute to determine the specific binding

44 uctural transition that accompanies the bulk MIT.

45 Active transport by MIT is driven by the proton electrochemical gradient acr

46 a conventional on-the-person database called MIT-BIH, and the second is one less uncontrolled off-the

47 1 complex shows that Vfa1 adopts a canonical MIT-interacting motif 2 structure that has been observed

48 f 99.3% and 99.6%, respectively, for the CHB-MIT dataset, and corresponding values of 98.0% and 98.3%

49 ed values less than 0.5/h for 92% of the CHB-MIT patients and less than 1.0/h for 80% of the EPILEPSI

50 -measure of 59.0% and AP of 54.5% on the CHB-MIT recordings, and comparatively lowers performances fo

51 signals from two different datasets: the CHB-MIT Scalp EEG database and the EPILEPSIAE project that i

52 and Synthesis (MLPDS) consortium, comprising MIT and 13 chemical and pharmaceutical company members.

53 Such a spatially confined MIT is corroborated by systematic characterizations on e

54 Vps4 and Vta1 both contain MIT domains, which bind to "MIT-interacting motifs" (MIM

55 recipients were divided into DA group (DA+; MIT>/=0.5 mm, n=23) or non-DA group (DA-; MIT<0.5 mm, n=

56 +; MIT>/=0.5 mm, n=23) or non-DA group (DA-; MIT<0.5 mm, n=15).

57 of 0.992) using an external validation data, MIT-BIH arrhythmia database.

58 that requires both their previously defined MIT interacting motifs and approximately 50 amino acids

59 that the IST1 terminus contains two distinct MIT interacting motifs (MIM1 and MIM2) that wrap around

60 AE were identical, whereas in lower dosages, MIT seemed more effective.

61 lating domains across the temperature-driven MIT in NdNiO3 epitaxial thin films.

62 t makes only limited contacts with the first MIT module.

63 .py is cross-platform, open-source and free (MIT licensed) software.

64 Tested upon a total of 107049 beats from MIT-BIH arrhythmia database, our method has achieved ave

65 z and Institute Professor Robert Langer from MIT discuss the significant challenges of administering

66 In particular, we show that two further MIT domain-containing proteins (AMSH/STAMBP and LOC12953

67 helical bundles, which interact with helical MIT-interacting motifs in ESCRT-III subunits.

68 were CMV-positive had a significantly higher MIT compared with those in the late group with negative

69 MIT), and the Massachusetts General Hospital/MIT Morris Udall Center of Excellence in Parkinson Disea

70 B(1)), Asp(300)(A(2)), and Glu(429)(B(2)) in MIT, are highly conserved with 96, 78, and 96% amino aci

71 hnology advances, additional developments in MIT are likely.

72 we explore the nature of a disorder induced MIT in functionalized graphene, a model 2D system.

73 ults of a project at the Whitehead Institute/MIT Center for Genome Research to construct such a physi

74 the pRML vector from the Whitehead Institute/MIT-820 mouse YAC library and from BACs in pBeloBAC11.

75 become iodinated to form mono-iodotyrosine (MIT) and/or di-iodotyrosine (DIT); however, selective ty

76 ina MiSeq sequencing, for H. saguini isolate MIT 97-6194-5, consisting of approximately 2.9 Mb with a

77 -III proteins IST1 and CHMP1B to LDs via its MIT domain to facilitate LD-to-peroxisome FA trafficking

78 ed: Vps2 can directly stimulate Vps4 via its MIT domain, whereas Vps60 stimulates via Vta1.

79 e software, available under the MIT License (MIT).

80 In contrast, the second LIP5 MIT module binds with unusually high affinity to a novel

81 aps almost completely around the second LIP5 MIT module but makes only limited contacts with the firs

82 trafficking (MIT) module of the tandem LIP5 MIT domain binds CHMP1B (and other ESCRT-III proteins) t

83 Mean MIT and mean II were significantly greater in the late g

84 partment of Defense, Ragon Institute of MGH, MIT, & Harvard, Bill & Melinda Gates Foundation, and Jan

85 substrates are initially recruited by an MIM-MIT interaction that activates the Vps4 central pore to

86 st1 interacts with the Did2 C-terminal MIM1 (MIT-interacting motif 1) via a novel MIM-binding structu

87 Mithramycin (MIT) and tolfenamic acid (TA) inhibit the activity of th

88 hemotherapeutic agents such as mitoxantrone (MIT) in multiple sclerosis (MS) patients justify the sea

89 ubule-interacting and trafficking molecules (MIT) at its N-terminus, and most proteins with MIT domai

90 ubule-interacting and trafficking molecules (MIT) domains comprising asymmetric three-helical bundles

91 15.0%) for a 1 degrees C increase in monthly MIT at <15, 15-64, and >/=65 years of age, respectively,

92 ties in electron-lattice dynamics and a Mott MIT where strong electron-electron correlations drive ch

93 st, at the surface, an unusual inherent Mott MIT is observed at 130 kelvin, also on cooling but witho

94 Ca(1.9)Sr(0.1)RuO4, such a first-order Mott MIT occurs in the bulk at a temperature of 154 kelvin on

95 As new MIT domain proteins are rapidly being identified, these

96 er; 374 were assigned MIT therapy and 374 no MIT therapy.

97 nths was lower with MIT therapy than with no MIT therapy (hazard ratio 0.35 (95% CI 0.15-0.82, p=0.01

98 Neither masked prayer nor MIT therapy significantly improved clinical outcome afte

99 Binding of a single NRBF2 MIT domain bends the helical solenoid of the VPS15 scaff

100 PI3KC3-C1 activation pathway driven by NRFB2 MIT domain binding.

101 (429) are critical for transport function of MIT.

102 gton and the other at the Broad Institute of MIT and Harvard, led to the development of a novel molec

103 se data support a model wherein a network of MIT and MIT-like domain interactions with ESCRT-III subu

104 of such phase coexistence in the vicinity of MIT leads to first-order transition in these manganites.

105 lifestyle or 8-10 weeks of isocaloric HIT or MIT.

106 d the structural basis that governs pairwise MIT-MIM interaction.

107 h two alternative starting points: a Peierls MIT driven by instabilities in electron-lattice dynamics

108 an open source R package under a permissive MIT license and includes detailed user documentation.

109 is open-source and free under the permissive MIT License (opensource.org/licenses/mit-license.php).

110 3 and freely available under the permissive MIT license.

111 Here, the proautophagic MIT domain-containing protein NRBF2 was used to map the

112 characterized ESCRT-III interacting protein, MIT-domain containing protein 1 (MITD1).

113 tion to the uncharged amides greatly reduced MIT transport function to 23% (E187Q), 1.4% (D300N), and

114 H. saguini MIT 97-6194-5 induced significant levels of interleukin-

115 Here, an atomic-scale MIT triggered by surface termination conversion in SrRuO

116 Binding of a second MIT stabilizes the VPS34 lipid kinase domain in an activ

117 To simulate MIT in NP films, we developed a hierarchical Kinetic Mon

118 g/software, distributed under an open source MIT license.

119 able through Bioconductor via an open source MIT license.

120 It is released under an Open source MIT license.

121 The software is open source (MIT license) and executable with Python 2.7 or iPython n

122 Both tools are open source (MIT license) and freely available for use online through

123 on Package Index via pip; it is open source (MIT license).

124 raversal algorithm (Gretel) are open source, MIT licensed and freely available online at github.com/s

125 Helicobacter hepaticus, and Helicobacter sp. MIT 94-022.

126 low-light-adapted strain Prochlorococcus sp. MIT 9313 has one iron-stress-induced pcb gene encoding a

127 based amino acid substitution in the spartin MIT domain (F24D) blocks the spartin-Ist1 interaction.

128 ance assays, we demonstrate that the spartin MIT domain binds with micromolar affinity to the endosom

129 infected with novel Helicobacter sp. strain MIT 96-1001.

130 oposed name Helicobacter aurati (type strain MIT 97-5075c) has been isolated from the inflamed stomac

131 Helicobacter cetorum, sp. nov. (type strain MIT 99-5656; GenBank accession number AF 292378), was cu

132 flexispira taxon 3, Helicobacter sp. strains MIT 94-022 and MZ 640285, and Helicobacter suis, respect

133 onovani has a myo-inositol/proton symporter (MIT) that is a member of a large sugar transporter super

134 isruption of the MRL protein-integrin-talin (MIT) complex markedly impairs cell protrusion.

135 Our studies thus reveal how the tandem MIT domain of LIP5 binds different types of ESCRT-III pr

136 ates and binds ESCRT-III subunits via tandem MIT domains, and thereby, delays abscission in response

137 The use of minimally invasive techniques (MIT) in patient care is well documented in ancient histo

138 t the Massachusetts Institute of Technology (MIT) Research Reactor.

139 arch, Massachusetts Institute of Technology (MIT), and the Massachusetts General Hospital/MIT Morris

140 odel system due to its near room temperature MIT temperature.

141 l influenza and monthly minimum temperature (MIT), monthly vapor pressure, school calendar pattern, a

142 f VPS4, LIP5, and Spartin via its C-terminal MIT-interacting motif (MIM).

143 (MIT) domains initially bind the C-terminal MIT-interacting motifs (MIMs) of ESCRT-III subunits, but

144 ain architecture that features an N-terminal MIT (microtubule interacting and trafficking) domain fol

145 n part by binding of Vps4 via its N-terminal MIT (microtubule interacting and trafficking) domain to

146 Deleting the N-terminal MIT domain and adjacent linker from VPS4A increased both

147 stinct elements: a poorly ordered N-terminal MIT domain that binds ESCRT-III substrates, large (mixed

148 The N-terminal MIT domains of the upper ring localize on the symmetry a

149 sted a bioassay, the mouse infectivity test (MIT), in this model.

150 oscopy of oocyte cryosections confirmed that MIT mutants were expressed on the oocyte surface in simi

151 icroscopy of oocyte cryosections showed that MIT mutants were expressed on the oocyte surface at a si

152 The MIT domain forms an asymmetric three-helix bundle that r

153 The MIT domain of Vps4 binds to the C-terminal 17 residues o

154 e change of the crystal structure across the MIT at finite temperature.

155 reedom with the crystal structure across the MIT in rare-earth nickelates.

156 O3 films with x = 0.33 and 0.375, across the MIT temperature.

157 ation length of these LPCMO films across the MIT.

158 In addition, the MIT motif-containing N-terminal domain, projected by a l

159 SCRT-III subunits with both the pore and the MIT domain simultaneously, which might be essential for

160 "working draft" of the human genome and the MIT shotgun assembly of the mouse genome, we performed a

161 rained NdNiO3 films both above and below the MIT temperature.

162 ngth for two films which increases below the MIT.

163 the 40-amino acid linker region between the MIT and the ATPase domain of Vps4 is not required for pr

164 bunits in yeast, only Vps2 and Did2 bind the MIT (microtubule interacting and transport) domain of Vp

165 IM1 mode, the additional ability to bind the MIT domain of Spartin in the MIM3 mode.

166 MP2A, a protein that normally only binds the MIT domain in the MIM1 mode, the additional ability to b

167 etion of the linker is expected to bring the MIT domains into close proximity to the central pore of

168 c and magnetic energy scales controlling the MIT.

169 bes the thermodynamic forces controlling the MIT.

170 Here we report that the entropy driving the MIT in VO2 is dominated by strongly anharmonic phonons r

171 f metallic and insulating regions during the MIT and the coupling of lattice strain to the local tran

172 ture ramp from heating to cooling during the MIT.

173 appeared, or in immunocompromised hosts, the MIT compared favorably to culture and PCR for infected N

174 to clean up Z1 and Z2 harmonic errors in the MIT 1.3-GHz high-resolution NMR magnet composed of an 83

175 Distinct pockets in the MIT domain bind three conserved leucine residues of the

176 into two groups: those with >/=0.5 mm in the MIT in any matched site (group 1) and those with MIT <0.

177 Our data provide new insights into the MIT of heteroepitaxial nickelates and point to a rich, n

178 tion temperature, as well as to maintain the MIT properties that would strengthen the potential of th

179 We propose that this localization of the MIT domain in linker-deleted Vps4 mimics a repositioning

180 r-deleted Vps4 mimics a repositioning of the MIT domain normally caused by binding of Vps4 to ESCRT-I

181 e between the first and third helices of the MIT domain.

182 Clear features of the MIT effect are evident from the deeply modulated ferroma

183 p around and bind in different groves of the MIT helical bundle.

184 bond length disproportionation model of the MIT in the rare-earth nickelates.

185 x)O(2)), and show that the hysteresis of the MIT in the system can be directly tuned by adjusting the

186 taR/R > 1,000%) and strong modulation of the MIT temperature (DeltaT(c) > 30 K) in a voltage-actuated

187 ehensively the ESCRT-III interactions of the MIT-domain family member MITD1 and identify strong inter

188 2) is responsible for the suppression of the MIT.

189 theory provides a better description of the MIT.

190 data in terms of two candidate models of the MIT: (a) as a Quantum Critical Transition, signaled by a

191 bustness of the effect shed new light on the MIT in complex oxides.

192 The compression performance is tested on the MIT-BIH Arrhythmia database producing compression result

193 ormula: see text] [Formula: see text] on the MIT-BIH/CYBHi databases.

194 ection of spirochetes in the CSF by PCR, the MIT, and culture was inversely related to the concomitan

195 A simple, controllable method to switch the MIT properties in real time is needed for practical appl

196 We show that the MIT domain binds to a subset of ESCRT-III subunits and t

197 tion shows that it is closely related to the MIT domain of Vps4.

198 ar complexes revealed that IST1 binds to the MIT domains of VPS4, LIP5, and Spartin using two differe

199 ed an anomalously low gap region next to the MIT.

200 and provided sufficient heat to trigger the MIT at a temperature around 60 degrees C, which is almos

201 e open-source software distributed under the MIT licence.

202 is open source software, available under the MIT License (MIT).

203 The software is distributed under the MIT License and is accompanied by example files and data

204 DRAW+SneakPeek is released under the MIT license and is available for academic and nonprofit

205 VCPA is released under the MIT license and is available for academic and nonprofit

206 The package is freely available under the MIT license from CRAN.

207 age is open source and distributed under the MIT license via GitHub along with examples, documentatio

208 and SneakPeek are freely available under the MIT license, and are available as Amazon machine images

209 is implemented in Python, released under the MIT License, and works on Linux, Windows, and MacOS.

210 tware code is free and open source under the MIT license, enabling institutions to install and users

211 s a free biobanking tool published under the MIT license.

212 mplemented in C++ and is available under the MIT License.

213 The source code is released under the MIT license.

214 oStructures.jl is freely available under the MIT license.

215 was implemented in C and released under the MIT license.

216 ge are for non-profit academic use under the MIT license.

217 l framework for the API, and it is under the MIT license.

218 implemented in Python and licensed under the MIT license.

219 The source code is licensed under the MIT License.

220 The source code is distributed under the MIT Open Source license agreement and is available for d

221 BioBIKE is distributed under the MIT Open Source license.

222 munities, all software is released under the MIT open source license.

223 iveness of robot-assisted training using the MIT-Manus robotic gym with an enhanced upper limb therap

224 hase that is observed in films for which the MIT is absent.

225 tal structure of LIP5NTD in complex with the MIT (microtubule-interacting and transport)-interacting

226 n PROS that mediate the interaction with the MIT domain of SKD1.

227 re of meiotic clade AAA ATPases may be their MIT domain, which is a module that is found in a wide va

228 that bind and recruit VPS4 ATPases via their MIT domains.

229 defined by ICUS as a mean intimal thickness (MIT) > or =0.3 mm in any coronary artery segment.

230 formed, including maximal intimal thickness (MIT) and intimal index (II).

231 On the basis of maximum intimal thickness (MIT) at BL, recipients were divided into DA group (DA+;

232 The change in maximal intimal thickness (MIT) from baseline to one year was recorded for several

233 croscopically for maximal intimal thickness (MIT), percentage of luminal circumference involved (PLCI

234 ular interactions between IST1 and the three MIT domain-containing proteins to understand the structu

235 ues (ATH) and macroscopically intact tissue (MIT) sampled from 32 patients were compared and an integ

236 on the oocyte surface in similar quantity to MIT wild type.

237 With reference to MIT, we examined the effect of ethonafide on experimenta

238 hracene-based antineoplastic drug similar to MIT.

239 ta1 both contain MIT domains, which bind to "MIT-interacting motifs" (MIMs) of ESCRT-III proteins.

240 essory prayer and music, imagery, and touch (MIT) therapy.

241 h a microtubule-interacting and trafficking (MIT) domain at the N terminus and a unique, unanticipate

242 the microtubule-interacting and trafficking (MIT) domain of Vps4.

243 its microtubule interaction and trafficking (MIT) domain, NRBF2 binds Atg14L directly and enhances At

244 ps4 microtubule-interacting and trafficking (MIT) domains initially bind the C-terminal MIT-interacti

245 the microtubule interacting and trafficking (MIT) domains of VPS4, LIP5, and Spartin via its C-termin

246 rst microtubule-interacting and trafficking (MIT) module of the tandem LIP5 MIT domain binds CHMP1B (

247 is superior to moderate-intensity training (MIT) in counteracting obesity-induced impairment of left

248 O3 exhibits a metal-to-insulator transition (MIT) as the temperature is lowered that is also seen in

249 The metal-to-insulator transition (MIT) closest to room temperature of 68-70 degrees C as s

250 ty change at the metal-insulator transition (MIT) has been extensively considered for the near-future

251 e existence of a metal-insulator transition (MIT) in highly disordered RuO2 nanoskins with carrier co

252 The metal-insulator transition (MIT) in transition-metal-oxide is fertile ground for exp

253 (LMR) and the metal-to-insulator transition (MIT) induced by magnetic field in heavily-doped Nb:STO (

254 s that feature a metal-insulator transition (MIT) is a key requirement for developing a new class of

255 ts a first-order metal-insulator transition (MIT) near room temperature, where conductivity is suppre

256 ng a first-order metal-insulator transition (MIT) offers unique opportunities to uncover their drivin

257 The metal-insulator transition (MIT) remains among the most thoroughly studied phenomena

258 gnetoresistance, metal-insulator transition (MIT) that may result from coexistence of ferromagnetic,

259 lic state is the metal-insulator transition (MIT).

260 films across the metal-insulator transition (MIT).

261 undergo a metal-insulator phase transition (MIT), the origin of which is still under debate.

262 chieved tunable metal-insulator transitions (MIT) in oxide heterostructures by inducing interfacial o

263 ions, which are metal-insulator transitions (MITs) driven by electron-electron interactions, are usua

264 itches based on metal-insulator transitions (MITs), etc.

265 and manifested metal-insulator transitions (MITs).

266 trate the magnetically-induced transparency (MIT) effect in Y[Formula: see text]Fe[Formula: see text]

267 VPS4A microtubule interacting and transport (MIT) domain and demonstrate that the VPS4A MIT domain bi

268 t the microtubule interacting and transport (MIT) domains of human VPS4A and VPS4B bind conserved seq

269 their microtubule interacting and transport (MIT) N-terminal domains and Vta1p co-factors.

270 otubule interacting and organelle transport (MIT) domain.

271 Here, Giovanni Traverso, MIT and Harvard Medical School Assistant Professor, and

272 ailable online at drugtargetor.com and under MIT licence.

273 It is implemented in C ++, distributed under MIT license and supported on Linux, OS X and Windows (wi

274 role in 5d(5) iridates (Ir(4+)), undergoing MITs both concurrent (pyrochlores) and separated (perovs

275 The performance evaluation using MIT-BIH arrhythmia database shows that our approach comp

276 ng and linkage analysis of hybrid mice using MIT microsatellite marker sequences localized the seizur

277 that recruitment to the protein lattice via MIT domains also relieves autoinhibition and primes the

278 Mutations that block VPS4 MIT-MIM2 interactions inhibit VPS4 recruitment, lysosoma

279 We now report that VPS4 MIT domains also bind a second, "MIM2" motif found in a

280 ratricopeptide-like repeat (TPR) of the VPS4 MIT domain, but in the opposite orientation to that of a

281 e Vps2 C terminus in a complex with the Vps4 MIT domain, explaining the basis for selective ESCRT-III

282 The solution structure of the VPS4 MIT-CHMP6 MIM2 complex revealed that MIM2 elements bind

283 Structures of VPS4A MIT-CHMP1A and VPS4B MIT-CHMP2B complexes reveal that th

284 (MIT) domain and demonstrate that the VPS4A MIT domain binds the C-terminal half of the ESCRT-III pr

285 Structures of VPS4A MIT-CHMP1A and VPS4B MIT-CHMP2B complexes reveal that the C-terminal CHMP mot

286 ate engagement is autoinhibited by the Vps4p MIT domain and that this inhibition is relieved by bindi

287 or Type 2 MIM elements, which bind the Vps4p MIT domain through different interfaces.

288 The structures suggest models in which Vps4p MIT and Vta1p domains engage ESCRT-III substrates above

289 .20 mm; SE = 0.03 mm) (both P<.025), whereas MIT in infected/treated versus control rabbits did not d

290 method to the leukemia data of the Whitehead/MIT group that attempts to differentially diagnose two k

291 tromeric and telomeric ends of the Whitehead/MIT recombinational maps.

292 YAC targeting technology (YTT) uses the WIBR/MIT-820 C57BL/6-mapped YAC library derived from the C57B

293 fide has less cardiac toxicity compared with MIT.

294 egalovirus (CMV) status were correlated with MIT and II.

295 Mortality at 6 months was lower with MIT therapy than with no MIT therapy (hazard ratio 0.35

296 he HbA(1c) level was higher in patients with MIT > or =0.3 mm than in those with MIT <0.3 mm (6.4% vs

297 T) at its N-terminus, and most proteins with MIT domains interact with specific ESCRT-III proteins.

298 nts with MIT > or =0.3 mm than in those with MIT <0.3 mm (6.4% vs. 5.7%, p < 0.05).

299 in any matched site (group 1) and those with MIT <0.5 mm (group 2).

300 reatment of pancreatic tumor xenografts with MIT and TA produced dose-dependent antitumor activity, a

301 oteins' extreme C-termini that overlap with "MIT interacting motifs" (MIMs) known to bind to VPS4.