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1 MRSA acquisition and infections were not impacted by the
2 MRSA and ESBL infections accounted for the majority of t
3 MRSA bloodstream infection (BSI) incidence per 100 000 p
4 MRSA causes fulminant keratitis often requiring surgical
5 MRSA possesses an arsenal of secreted host-damaging viru
6 MRSA resistance to beta-lactam antibiotics is mediated b
9 00 patients decreased between 2007 and 2016 (MRSA acquisitions, 25.4 to 4.1; and C. difficile acquisi
13 sensitive to changes in the probability of a MRSA-negative patient acquiring MRSA during their hospit
14 lts indicate little reason for concern about MRSA transmission in low-prevalence settings in the imme
18 he jugular-vein catheter before or 6 h after MRSA inoculation, while an equal volume of saline was ad
22 unique mode of action that is active against MRSA, but its clinical use is restricted to topical admi
23 ated excellent bactericidal activity against MRSA at concentrations >= 10% of honey, with vacuum-prep
24 The TZP combination lacks activity against MRSA, yet it synergized with compound 73 to kill MRSA in
27 ATG16L1 is necessary for protection against MRSA strains encoding alpha-toxin(4)-a pore-forming toxi
28 s active as rifampin with vancomycin against MRSA in rat foreign body osteomyelitis, suggesting that
35 e models including small-colony variants and MRSA status, P aeruginosa was not independently associat
37 cillin-resistant Staphylococcus aureus [anti-MRSA] agents, and antipseudomonal agents) was analyzed u
45 s community-acquired and hospital-associated MRSA strains which are resistant to multiple drugs inclu
46 S aureus and meticillin-resistant S aureus (MRSA) can adapt to form slow-growing, antibiotic-resista
47 red in both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) strai
48 episodes of methicillin-resistant S. aureus (MRSA) bacteremia, with a rising proportion due to MSSA (
49 , including methicillin-resistant S. aureus (MRSA), has become a worldwide, major health care problem
54 Conversely, methicillin-resistant S. aureus (MRSA; the drug resistant strain) is able to grow on gel
55 methicillin-resistant Staphylococcus aureus (MRSA) and a Kirschner wire (K-wire) implanted in each.
56 methicillin-resistant Staphylococcus aureus (MRSA) and bolsters the innate immune response to infecti
57 Methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections declined acro
58 methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli Time-kill and transmission el
60 methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa and accelerates their r
61 methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecalis (VR
62 methicillin-resistant Staphylococcus aureus (MRSA) are at high risk for infection after discharge.
63 Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with mortality of more th
67 methicillin-resistant Staphylococcus aureus (MRSA) causes life-threatening necrotizing pneumonia in c
68 methicillin-resistant Staphylococcus aureus (MRSA) colonization among nursing home residents is high.
70 methicillin-resistant Staphylococcus aureus (MRSA) for various infections, there are no recommendatio
71 methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a frequent cause of purulent skin a
72 methicillin-resistant Staphylococcus aureus (MRSA) has emerged as the dominant pathogen found in bact
73 methicillin-resistant Staphylococcus aureus (MRSA) identifies unsuspected transmission events and out
74 methicillin-resistant Staphylococcus aureus (MRSA) in an environment with or without stressor by addi
76 methicillin-resistant Staphylococcus aureus (MRSA) infection can quickly develop into severe, necroti
77 Methicillin-resistant Staphylococcus aureus (MRSA) infections cause significant mortality and morbidi
80 Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of health care-associated infect
81 methicillin-resistant Staphylococcus aureus (MRSA) is a cornerstone of many antibiotic regimens; howe
82 methicillin-resistant Staphylococcus aureus (MRSA) is a cornerstone of many antibiotic regimens; howe
83 Methicillin resistant Staphylococcus aureus (MRSA) is a major human pathogen, which causes superficia
84 Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of ventilator-associated pne
85 Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern pathogens.
86 Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most widespread antibiotic-resistant
87 methicillin-resistant Staphylococcus aureus (MRSA) isolated from the patients' hand and room surfaces
88 methicillin-resistant Staphylococcus aureus (MRSA) isolates to determine if there are transmission ne
91 methicillin-resistant Staphylococcus aureus (MRSA) prevalence-not MRSA colonization-were the primary
92 methicillin-resistant Staphylococcus aureus (MRSA) remains controversial despite existing guidelines.
93 Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the most common causes of health ca
94 methicillin-resistant Staphylococcus aureus (MRSA) strain epidemiology has changed since the rise of
95 methicillin-resistant Staphylococcus aureus (MRSA) strains poses a major threat to public health.
100 methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococcus (VRE), extended
101 methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), Pseudomo
102 methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecalis/faeciu
103 methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus spp. (VRE), ext
107 ith SaB (47 methicillin-resistant S. aureus [MRSA], 12 methicillin-sensitive S. aureus [MSSA]) from 2
108 s and inhibit antibiotic-resistant bacteria (MRSA and Pseudomonas aeruginosa), the most common cause
110 iable analyses, prior year SSTI and baseline MRSA colonization were associated with cumulative SSTI.
111 hicillin-resistant Staphylococcus aureus (CA-MRSA) is threatening public health as it spreads worldwi
112 hicillin-resistant Staphylococcus aureus (CA-MRSA) SSTI, their household contacts, and pets were enro
115 ently labelled wild-type and mecA-deleted CA-MRSA USA400 strains across ~57,000 compounds supplemente
116 tors underlying the epidemic expansion of CA-MRSA lineages such as USA300, the predominant CA-MRSA cl
117 lineages such as USA300, the predominant CA-MRSA clone in the United States, are largely unknown.
122 cas + fusC + ccrA/B-1], CC8-MRSA-V/VT, CC22-MRSA-[IV + fusC + ccrAA/(C)], CC45-MRSA-[IV + fusC + tir
124 /VT, CC22-MRSA-[IV + fusC + ccrAA/(C)], CC45-MRSA-[IV + fusC + tir], CC80-MRSA-IVa, CC121-MRSA-V/VT,
125 identified include CC5-MRSA-V (edinA+), CC5-MRSA-[VT + fusC], CC5-MRSA-IVa (tst1+), CC5-MRSA-[V/VT +
126 5-MRSA-V (edinA+), CC5-MRSA-[VT + fusC], CC5-MRSA-IVa (tst1+), CC5-MRSA-[V/VT + cas + fusC + ccrA/B-1
127 Novel MRSA strains identified include CC5-MRSA-V (edinA+), CC5-MRSA-[VT + fusC], CC5-MRSA-IVa (tst
129 -MRSA-[VT + fusC], CC5-MRSA-IVa (tst1+), CC5-MRSA-[V/VT + cas + fusC + ccrA/B-1], CC8-MRSA-V/VT, CC22
131 CC5-MRSA-[V/VT + cas + fusC + ccrA/B-1], CC8-MRSA-V/VT, CC22-MRSA-[IV + fusC + ccrAA/(C)], CC45-MRSA-
133 crAA/(C)], CC45-MRSA-[IV + fusC + tir], CC80-MRSA-IVa, CC121-MRSA-V/VT, CC152-MRSA-[V + fusC] (PVL+).
134 tic linezolid has been useful in controlling MRSA-related VAP infections; however clinical benefit do
136 aluate whether contact precautions decreased MRSA acquisition in LTCFs, compared to standard precauti
137 ctions, but treatment failures occur despite MRSA strains being tested susceptible according to stand
138 a method to specifically capture and detect MRSA directly from patient nasal swabs with no prior cul
140 -lactams in vitro and significantly enhanced MRSA eradication by oxacillin in a mouse bacteremia mode
142 bly, topical auranofin completely eradicated MRSA (8-log(10) reduction) in infected PUs of obese mice
146 oints higher in the prespecified exploratory MRSA subgroup (74.1% vs. 31.3%, difference = 42.8, 90% C
148 th overlap in their feeder ACHs (P < .05 for MRSA, VREfc, and CipREc), limited phylogenetic clusterin
149 peptides (adjusted odds ratio [aOR], > 2 for MRSA and VREfc/VREfm) or third-/fourth-generation cephal
151 than use of a nares surveillance culture for MRSA colonization, which is current clinical practice fo
154 n 2012 and 2017, the incidence decreased for MRSA infection (from 114.18 to 93.68 cases per 10,000 ho
156 eated with daptomycin plus a beta-lactam for MRSA bloodstream infection had lower odds of composite c
157 that the adjunctive role of beta-lactams for MRSA in select patients helps elicit favorable host cyto
162 us, to develop better clinical solutions for MRSA persistence and relapse, our modeling results indic
166 patients treated with >= 72 hours of VAN for MRSA cSSTI from 2008-2013 at Detroit Medical Center.
168 paring rates in 2007/08 and 2015/16, was for MRSA (97%), followed by P. aeruginosa (81%), S. aureus (
170 ether, the present data reveal that EVs from MRSA play a crucial role in the survival of beta-lactam
173 Staphylococcus aureus ST45 is a major global MRSA lineage with huge strain diversity and a high clini
178 , respectively, with a notable difference in MRSA patients (3.7% vs. 25.0%, difference = -21.3, 90% C
182 -0.90), suggesting that the observed rise in MRSA infections is not due to an ongoing epidemic but dr
183 vity against strains of S. aureus (including MRSA) was not affected in the presence of higher bacteri
187 illance and collecting isolates for invasive MRSA (ie, from normally sterile body sites), 2005-2013.
189 e impact of combination therapy for invasive MRSA infections.Patients treated with daptomycin plus a
190 ng important for the development of invasive MRSA infections and are thus potential targets for antiv
193 ne administered with vancomycin yielded less MRSA from bones (0.10, 3.02, and 0.10 log10 CFUs/g, resp
194 ged to major healthcare-associated lineages: MRSA (sequence type [ST] 5); VREfc (ST6); CipREc (ST131)
197 a Panton-Valentine leucocidin (PVL)-negative MRSA isolate from patient sputum, we show that linezolid
199 ehold transmission accounted for half of new MRSA acquisitions, indicating this setting as a potentia
201 Staphylococcus aureus (MRSA) prevalence-not MRSA colonization-were the primary drivers of prescribin
205 Fifty-two culture-proven (52 eyes) cases of MRSA keratitis diagnosed and treated at the University o
206 Emirates (UAE), genetic characterisation of MRSA identified between December 2017 and August 2019 wa
207 lly relevant strain from the USA300 clone of MRSA, responds to avibactam by up-regulating the express
208 itro activity of CPT against a collection of MRSA isolates collected between 1999 and 2018 from nine
211 Genetically diverse, the epidemiology of MRSA is primarily characterized by the serial emergence
215 linezolid significantly improved killing of MRSA by dysfunctional neutrophils, which was supported b
218 rmine the negative predictive value (NPV) of MRSA screening in the determination of subsequent positi
219 rmine the negative predictive value (NPV) of MRSA screening in the determinization of subsequent posi
224 recent injection drug use were predictors of MRSA. Among HIV patients, recent injection drug use, cur
228 WGS revealed that the high prevalence of MRSA in Clinic A was not due to clonal spread in the cli
231 ds contact precautions for the prevention of MRSA within acute care facilities, which are being used
232 In addition, a substantial proportion of MRSA infections occur after discharge from the hospital.
237 ent against USA300 and additional strains of MRSA and displayed as importantly no cytotoxicity in fou
244 lly detected both spa and SCCmec variants of MRSA and correctly identified empty-cassette strains of
249 The sensitivity and specificity for positive MRSA clinical culture were 67.4% and 81.2%, respectively
252 indicated that the use of routine, proactive MRSA sequencing would be associated with estimated cost
253 relatedness based on mapping to a reference MRSA genome and detection of pairwise core genome single
255 s (SA), especially methicillin-resistant SA (MRSA), is a significant cause of morbidity and mortality
259 A, CC5-MRSA-IV Sri Lanka Clone and ST5/ST225-MRSA-II, Rhine-Hesse EMRSA/New York-Japan Clone in our s
260 hus, identifying the factors that cause such MRSA persistence is of direct and urgent clinical releva
269 ed to a lower risk of hospitalization due to MRSA infection (hazard ratio, 0.71; 95% CI, 0.51 to 0.99
270 was based on the relative reduction in total MRSA acquisitions in a cohort of hospitalized patients i
271 d which patients are more likely to transfer MRSA to HCP and to identify which HCP interactions are m
272 dentify residents who are likely to transmit MRSA to HCWs' hands and clothing during clinical care is
273 irmatory study focused on exebacase to treat MRSA BSIs.TRIAL REGISTRATIONClinicaltrials.gov NCT031634
298 s with MSSA were more likely than those with MRSA to have no underlying medical conditions (adjusted