ライフサイエンスコーパス: Mendelian ratio

1 s, and male Pgam5(-/-) mice were born at sub-Mendelian ratio.

2 type, heterozygous, and homozygous mice in a Mendelian ratio.

3 fl);Nr5a1-Cre(/+) mice were born at a normal Mendelian ratio.

4 bearing progeny rather than the expected 1:1 Mendelian ratio.

5 ding of the mutant mice yielded the expected mendelian ratio.

6 ly normal homozygous mutant mice at a normal Mendelian ratio.

7 ll mice were viable and born at the expected Mendelian ratio.

8 c loci, with inheritance conforming to a 3:1 Mendelian ratio.

9 disease phenotype deviated from the expected Mendelian ratio.

10 -/-) mice that were not born at the expected Mendelian ratio.

11 kout (mVps34(pdKO)) mice, which were born at Mendelian ratios.

12 expressing Y265C pol beta are born at normal Mendelian ratios.

13 ull for Eset were recovered but in less than Mendelian ratios.

14 mice are viable but not born in the expected Mendelian ratios.

15 s a semidominant transgene and segregated in Mendelian ratios.

16 (-) mouse crosses, were born at the expected Mendelian ratio (26.5%; n = 1,080 pups), indicating no e

17 ty and abnormal embryonic growth with skewed Mendelian ratios after day E18.5.

18 ing of heterozygous mutants yielded a normal Mendelian ratio among embryos on gestation day 9.5; howe

19 IKfyve(WT/KO) mice were born at the expected Mendelian ratio and developed into adulthood.

20 onal knockout mice were born at the expected Mendelian ratio and developed normally to adulthood, ind

21 ozygous knock-in animals were born in normal Mendelian ratio and developed normally to adulthood.

22 bKO animals were born close to the expected Mendelian ratio and developed without overt histological

23 -/- mice are live-born at below the expected Mendelian ratio and die at a weaning age with cystic kid

24 mafF null mutant mice were born in a normal Mendelian ratio and displayed no obvious functional defi

25 -) mice were born at a significantly reduced Mendelian ratio and exhibited high mortality between 3 t

26 zygous for DeltaPR were born at the expected Mendelian ratio and exhibited obesity plus insulin resis

27 omozygous Adam17 cyto animals were born at a Mendelian ratio and survived into adulthood with slightl

28 CCR2-/- mice were born at the expected Mendelian ratios and developed normally.

29 Parc knockout mice were born at the expected Mendelian ratios and exhibited no apparent phenotype.

30 Gpr27 knockout mice were born at expected Mendelian ratios and exhibited no gross abnormalities.

31 sphatase-negative mice were born in expected Mendelian ratios and exhibited normal growth and develop

32 Global tbeta4-knockout mice were born at mendelian ratios and exhibited normal heart and blood ve

33 Nlrp2-deficient mice were born with expected Mendelian ratios and that Nlrp2 was dispensable for inna

34 e is well under that predicted by the normal Mendelian ratio, and TR4(-/-) mice demonstrate high rate

35 The Mcoln1(-/-) mice are born in Mendelian ratios, and both male and female Mcoln1(-/-) m

36 ADAM33-null mice were born at expected Mendelian ratios, and both male and females developed no

37 ZO-1cKO mice were viable, had normal Mendelian ratios, and had a normal lifespan.

38 nd colonic enterocytes were born in expected Mendelian ratios, and RelA-null epithelia differentiated

39 amin A/C and emerin are born at the expected Mendelian ratio, are grossly normal at birth but have sh

40 The lal-/lal- mice are born in Mendelian ratios, are normal appearing at birth, and fol

41 s Nrp1(Y297A/Y297A) mice were born at normal Mendelian ratios, arguing against NRP1 functioning exclu

42 pups were represented at the expected normal Mendelian ratios at 1 to 3 days of age but at only 10% o

43 Pure F2 Parp1(+/A) embryos were found at Mendelian ratios at the E3.5 blastocyst stage but died b

44 amin A/C and emerin are born at the expected Mendelian ratio but had a shorter lifespan than those on

45 Klf5 mutant mice were born at a normal Mendelian ratio but had high mortality compared with con

46 rdial Dicer mutant mice are born in expected Mendelian ratios but die immediately after birth with pr

47 These mice are born at the expected Mendelian ratio, but die prematurely from spontaneous ca

48 zygous mutant mice were born at the expected Mendelian ratio, but their growth was impaired.

49 f4(loxP/loxP) mice were born at the expected Mendelian ratio, but they gradually died after birth.

50 These mice are born at normal Mendelian ratios, but display a progressive, systemic hy

51 ed knockouts develop normally, being born in Mendelian ratios, but fail to thrive within 2 weeks, dis

52 ound, knockout animals were also born at sub-Mendelian ratios, but many Adgrl1 null mice survived ges

53 c25a28 (encoding Mfrn2) are born at expected Mendelian ratios, but show decreased male fertility due

54 xpress KrasG12D in utero, are born at normal Mendelian ratios, develop hepatosplenomegaly, anemia, an

55 f the mutated gene were born in the expected Mendelian ratio, developed normally, and showed no appar

56 FLKO mice, while born at a normal Mendelian ratio, developed severe anemia and exhibited p

57 unable to interpret his own data that showed Mendelian ratios, even though he shared with Mendel a mo

58 VENIRKO mice were born at the expected Mendelian ratio, grew normally, were fertile, and exhibi

59 omozygous cardiac betaStop mice were born at Mendelian ratio, had a normal life expectancy, and norma

60 Btbd12-deficient animals are born at sub-Mendelian ratios, have greatly reduced fertility, are de

61 eficient mice are grossly normal and born in Mendelian ratios; however, deficiency of Mmp1a results i

62 onditional mutants were born at the expected Mendelian ratios; however, these died shortly after birt

63 gene was found to be transmitted at a normal Mendelian ratio in mice, in striking contrast to the pro

64 PAK4 knock-out (KO) mice were born at Mendelian ratios in both genders.

65 uble mutant embryos is lower than that for a Mendelian ratio, indicating deletion of Thm1 and Thm2 ca

66 TAFI mice produced offspring in the expected Mendelian ratio, indicating that transmission of the mut

67 c25B and Cdc25C are obtained at the expected Mendelian ratios, indicating that Cdc25B and Cdc25C are

68 minant involved in the generation of the non-Mendelian ratio is epigenetic.

69 In mice lacking Msy2, a normal Mendelian ratio is observed after matings between hetero

70 Although born in a normal mendelian ratio, no PGT(-/-) mice survived past postnata

71 (a/a) to A(vy)/a offspring from the expected Mendelian ratio of 1:1.

72 a KO:Het:WT ratio approximating the expected Mendelian ratio of 1:2:1.

73 d progeny of R1 plants, Tnt1 segregated in a Mendelian ratio of 3:1 and no new Tnt1 transposition was

74 duced normal-sized and shrunken seeds in the Mendelian ratio of 3:1, and the shrunken seeds could not

75 The unexpected Mendelian ratio of 4.4% cKO mice was confirmed by genoty

76 his background, we also obtained less than a Mendelian ratio of null offspring suggesting development

77 ned as a significant departure from expected Mendelian ratios of inheritance of an allele or chromoso

78 lta4A/tmDelta4A) offspring with the expected Mendelian ratios of inheritance, and these mice expresse

79 In contrast, we observed appropriate Mendelian ratios of RA+ mAgt+/+, RA+ mAgt+/-, and RA+ mA

80 Despite appropriate Mendelian ratios of RA- mice that were wildtype (+/+), h

81 heterozygous matings produced mutant mice at Mendelian ratios that had normal viability and fertility

82 (-/-) embryos were detected at the expected Mendelian ratios up to late preimplantation stage (E4.5)

83 Arl3 (-/-) mice were born at a sub-Mendelian ratio, were small and sickly, and had markedly

84 ulations made with odc2 mutants segregate in Mendelian ratios, while ht-a mutants have little effect,

85 breviated Sca(+/AE)) mutant mice are born in Mendelian ratios with no apparent abnormalities in growt

86 homozygous mutants were born at the expected Mendelian ratio without apparent developmental abnormali

87 us mutant mice (Brca1(FL/FL)) were born at a Mendelian ratio without obvious developmental defects.

88 Appl1-null mice were born at expected Mendelian ratios, without obvious phenotypic abnormaliti