ライフサイエンスコーパス: N terminus

1 A in a position shifted toward the peptide's N terminus.

2 eus via a nuclear localization signal in its N terminus.

3 osure and efficient myristoylation of the MA N terminus.

4 lar domain and another within its disordered N terminus.

5 eractions of basic amino acids in the BigDyn N terminus.

6 et sites are in a single cluster in the CYK4 N terminus.

7 eptor major subpocket by the CXCL12 proximal N terminus.

8 linked by ZP1, a protein with a proline-rich N terminus.

9 o acid-long, highly acidic sequence near the N terminus.

10 negatively affected when YiaC acetylated its N terminus.

11 differ only by the sequence position of the N terminus.

12 med for the adjacent cysteine motif on their N terminus.

13 rrent through targeting a site(s) within the N terminus.

14 a highly atypical PIP box located at the p12 N terminus.

15 e, which was alleviated upon deletion of its N terminus.

16 FBXO44 through a stretch of residues in its N terminus.

17 ested the X position reorients the chemokine N terminus.

18 of Kv1.5 communicates with the intracellular N terminus.

19 tic residues are introduced into its soluble N terminus.

20 ect against neurotoxicity carried out by its N terminus.

21 C-terminal regulation of its otherwise toxic N terminus.

22 ator due to residues that interacts with the N-terminus.

23 ly labeled acetyl-cysteine at the maleylated N-terminus.

24 of PrP(C) , attenuating the toxicity of the N-terminus.

25 ding the TOPLESS Domain (TPD) located in the N-terminus.

26 don, likely representing the bona fide CLOCK N-terminus.

27 rdinated interaction with the phosphorylated N-terminus.

28 e that rPrP interacts with the RNAs with its N-terminus.

29 eviously non-described interactions with the N-terminus.

30 ifies a novel KLTF peptide motif in the Cik1 N-terminus.

31 vage of isoseramox produced a native peptide N-terminus.

32 difications to the hydrophobic moiety at the N-terminus.

33 n additional microtubule binding site in the N terminus [1-4].

34 tive steps: (1) selective maleylation at the N-terminus; (2) labeling at the epsilon-NH(2) group of t

35 the chimeric receptor CCR5(QTY) (7TM)-CXCR4 (N terminus+3 EC loops), but with lower affinity compared

36 We engineered within its N terminus a motif conserved among natural peptides with

37 little effect on CXCL12 binding to the CXCR4 N terminus, a major component of the chemokine-GPCR inte

38 ide with an unprecedented Trp residue at its N-terminus, a peptide we have named fuscanodin.

39 differing conformational flexibility at the N-terminus, ability to form higher order aggregates and

40 n contrast, enhancing the cationicity of the N-terminus abrogates its ability to trigger channel cond

41 of multiple cysteine residues of the NOTCH3 N terminus activated proteolytic release of the first EG

42 ted amphipathic alpha-helix in the prodomain N terminus adopt helical structure in a membrane-mimetic

43 activates the gamma-tubulin complex via its N terminus, allowing nuclear microtubule polymerization

44 determined the crystal structures of CENP-I N-terminus alone from Chaetomium thermophilum and its co

45 Finally, the N-terminus, although not directly involved in the E2 bin

46 ors into the membrane, and the arginine-rich N-terminus (amino acids 1-27) drives membrane disruption

47 Specifically, we replaced the N terminus and 3 EC loops of CCR5(QTY) with the N termin

48 erminus and 3 EC loops of CCR5(QTY) with the N terminus and 3 EC loops of CXCR4.

49 designed chimeric receptors by switching the N terminus and 3 extracellular (EC) loops between differ

50 helices with an extracytoplasmically located N terminus and cytoplasmically located C terminus.

51 -end rule-mediated degradation of the NLRP1B N terminus and freeing the NLRP1B C terminus to activate

52 ease-causing mutations are restricted to the N terminus and how they cause human disease has been unc

53 e to contributions from glycosylation of the N terminus and palmitoylation of the C terminus of CB(2)

54 is translated into a protein that shares the N terminus and potentially some functions with the full-

55 re located within flexible regions of the gH N terminus and the gL C terminus, while the fifth was pl

56 nonnative interaction between the disordered N terminus and the hydrophobic C terminus of the peptide

57 mutational sensitivity of the fusion peptide N terminus and the length sensitivity of the transmembra

58 C(H)2s has a 7-residue deletion at the N-terminus and a 16-residue C-terminal extension contain

59 s of the tail-tube protein are braced by the N-terminus and a beta-hairpin loop, and interconnected a

60 P, which cleaves the Arg5,6 precursor at its N-terminus and at an internal site.

61 induction by binding partner proteins on its N-terminus and C-terminus domains and creating a superco

62 Enhancing the hydrophobicity of the N-terminus and cationicity of the C-terminus in temporin

63 f a novel interface between the CXCR4 distal N-terminus and CXCL12 beta1-strand, while also recapitul

64 e to the non-neutralizing epitopes on the E1 N-terminus and E2 hypervariable region 1 did not differ

65 d state associated with unfolding of the MCP N-terminus and straightening of E-loops.

66 We observe that the more exposed the N-terminus and the beginning of the NAC region of aSyn a

67 which are located in the region between the N-terminus and the loop 1 of rDer f 21 were identified a

68 sults suggest there is crosstalk between the N-terminus and the Mg(2+) binding site, and that N-acety

69 t NAA80 has partly disordered regions in the N-terminus and the proline-rich loop, the latter of whic

70 TALI forms specific interactions between the N-terminus and the transmembrane domain.

71 ciated variants cluster in the extracellular N-terminus and transmembrane domains 1-3, with more seve

72 LAPTM4B-24 lacks the extreme N-terminus and, contrary to LAPTM4B-35, failed to promot

73 a cryptic actin-binding sequence near JMY's N terminus, and STRAP inhibits JMY's ability to nucleate

74 fragments indicated unfolding started at the N-terminus, and the charge states of UVPD fragments enab

75 NMR spectroscopy showed that residues of the N terminus are involved in binding to CCL5.

76 n the imperfect KTKEGV repeats of the alphaS N-terminus, are increased.

77 e modulatory properties depended on MyBP-C's N terminus as N-terminal proteolysis attenuated MyBP-C's

78 , we report the crystal structure of the PKD N terminus at 2.2 angstrom resolution containing a previ

79 pped the site of fragmentation to the NOTCH3 N terminus at the peptide bond joining Asp(80) and Pro(8

80 depends on the extent to which the receptor N terminus binds the chemokine.

81 Importantly, we found that the Cse4 N-terminus binds with high affinity to the Ctf19 complex

82 Both peptides have their N terminus bound at the active site and extend away alon

83 cture of a short motif in the disordered XPA N-terminus bound to the RPA32C domain.

84 induce proteasomal degradation of the NLRP1B N terminus but not via the N-end rule pathway.

85 truncated AtPRMT3 protein bearing the entire N-terminus but lacking an intact enzymatic activity doma

86 (TM) 5, which, together with release of the N-terminus but without coupled movement of TM1, opens a

87 ed by proteolytic cleavage of their receptor N terminus by enzymes such as thrombin, trypsin, and cat

88 box enables hyperphosphorylation of the Ana2 N terminus by Plk4.

89 g a cyclic cell-penetrating peptide to their N-terminus, C-terminus, or stapling unit.

90 ystem, we find that CTCF mutants lacking the N-terminus cannot insulate TADs properly.

91 mutations in a PEST-like domain near the LLO N terminus cause enhanced LLO translation during intrace

92 2+)-free KRAS-GMPPNP structure, the flexible N-terminus causes conformational changes around residue

93 Mg(2+)-free KRAS-GDP structure, the flexible N-terminus causes conformational changes in the interswi

94 ctors, such as the follow-up sequence at the N terminus, conformation, flexibility, and protein local

95 well as a shorter isoform, EVI1, lacking the N-terminus containing the PR-SET domain (DeltaPR).

96 (diC8PIP(2)), stimulated GAP activity on an N terminus-containing variant, [L8K]ARF1, but only margi

97 receptor-chemokine interaction in which the N terminus contributes only to binding affinity.

98 The unstructured character of the N-terminus, coupled with its high content of negative ch

99 H26 enzyme with a CBM35 module linked to its N terminus (CrMan26) from a cattle rumen metatranscripto

100 middle of factor V by thrombin, yielding an N terminus-derived heavy chain and a C terminus-derived

101 UCN1 adopts a single straight helix with its N terminus dipped into the receptor transmembrane bundle

102 ains multiple PCNA-interaction motifs in its N terminus, each of which is essential to its ability to

103 The 3D(pol) N terminus encodes a nuclear localization signal (NLS) s

104 The structure revealed that the N terminus exhibits an alternative fold that converts th

105 muscle contractility, presumably through its N terminus extending from the thick filament and interac

106 -terminus embedded within the Z-disk and its N-terminus extending out toward the thin filament pointe

107 ing factor (RRF(mt)) carries a mito-specific N terminus extension (NTE), which is necessary for the f

108 nconventional fashion with the myristoylated N-terminus facing the lumen of the micronemes.

109 t the X residue helps to position the CXCL12 N terminus for optimal docking into the orthosteric pock

110 receptors (GPHR) have a large extracellular N-terminus for hormone binding.

111 l changes leading to release of the flexible N-terminus from the docking interface.

112 of MPST, differing by 20 amino acids at the N terminus, give rise to the cytosolic MPST1 and mitocho

113 These include modifications of the N terminus, glycosylation, phosphorylation, oxidation, a

114 x helicase DDX43 contains a KH domain in its N-terminus; however, its function remains unknown.

115 rative (n = ~8), suggesting that the cMyBP-C N terminus impacts the rotational dynamics of actin span

116 eptor selectivity by orienting the chemokine N terminus in a subfamily-specific direction.

117 ve enzyme complex, suggesting a role for the N-terminus in autoinhibition.

118 beta-(1->3)-linked d-Galp, whereas the WbbY N terminus includes a GT-B enzyme adding alpha-(1->3)-li

119 therin) contains 12 extra amino acids in its N terminus, including a dual tyrosine motif (YDYCRV) tha

120 nd that BIK1-mediated phosphorylation on its N terminus increases this channel activity.

121 reveals that PACAP27 engages VIP1R with its N-terminus inserting into the ligand binding pocket at t

122 T) was partly mediated by an increase in the N terminus insertion and, as shown by X-ray crystallogra

123 ain and the other pathway terminating at the N terminus insertion site.

124 Here we show that a segment within the CTCF N terminus interacts with the SA2-SCC1 subunits of human

125 ucial for its protective role over the toxic N-terminus, irrespective of alpha-cleavage or the cis-in

126 Combined with recent evidence that the N terminus is a toxic effector regulated by the C termin

127 suggest that each skeletal MyBP-C isoform's N terminus is functionally distinct and has modulatory c

128 This extended N terminus is important for protein stability because de

129 T-Rit2 surface dissociation and that the DAT N terminus is required for both PKC-mediated DAT-Rit2 di

130 ression of the cytosolic, positively charged N terminus is sufficient to block TA protein insertion i

131 Positive charge adjacent to the native N terminus is surprisingly beneficial for successful ext

132 Mvp1 lacking its N-terminus is dimeric and exhibits enhanced membrane ass

133 ated IL-36alpha supports the notion that the N-terminus is necessary for association with its cognate

134 end of thin filaments, where the tropomyosin N-terminus is not blocked by an adjacent tropomyosin pro

135 We showed that a free N-terminus is required for 3B to function as a primer an

136 High-affinity binding of InsP(8) to the XPR1 N-terminus (K (d) = 180 nM) was demonstrated by isotherm

137 channels is a highly conserved domain on the N terminus, known as the eag domain, consisting of a Per

138 This reduction required the Kir N terminus (KNtp), consistent with KNtp occupying a "tra

139 Deletion of this N terminus leads to functionally non-inactivating channe

140 However, a construct carrying preMalE at the N-terminus led to SecA targeting to SecYEG via the nativ

141 ins throughout the protein's sequence on the N terminus (Lys-118 and Lys-129), helicase domain (Lys-5

142 rm where a conserved, flexible region in the N-terminus masks the [4Fe-4S] cluster at the docking int

143 We propose that the NRPD1 N-terminus motif evolved to regulate Pol IV function in

144 ere tryptophan residues are located near the N terminus, near the middle, and near the inserting C-te

145 e non-aggregation prone PHF6 with a standard N terminus (NH(3) (+)-PHF6).

146 spite the presence of a kinase domain at the N-terminus, no COP1-independent role of SPA proteins has

147 d to ATP with and without UFM1 show that the N-terminus not only is directly involved in ATP binding

148 The p53 N terminus (NT) contains two transactivation domains (TA

149 Here we show that the N-terminus (NT) of ASIC1a interacts with its CT to form

150 te, where the phosphate moiety sits atop the N terminus of an alpha-helix.

151 in Sas4 interacts with a short region in the N terminus of Ana2/STIL.

152 s (DBD) of AR, and its autoinhibition by the N terminus of AR.

153 tucked under the corrin ring, displacing the N terminus of ATR, which is disordered.

154 found that docking of deoxyhemoglobin at the N terminus of band 3 displaces the protein with no lysin

155 sitides change the local conformation of the N terminus of beta-ENaC, and two sites of gamma-ENaC adj

156 seven transmembrane helices of CCR5, and the N terminus of CCR5 contacts the CD4-induced bridging she

157 Here, we show that Qtip interacts with the N terminus of cI(VP882), inhibiting both cI(VP882) DNA b

158 demonstrate that Rubisco interacts with the N terminus of CsoS2, a multivalent, intrinsically disord

159 We demonstrate that the N terminus of CTCF interacts with cohesin which explains

160 The N terminus of DGAT1 interacts with the neighbouring prot

161 recise locations of the previously ambiguous N terminus of DRC4 and C terminus of DRC5.

162 ctly interacts with E4orf3 via the conserved N terminus of E1A to regulate the expression of viral ge

163 of ERFE, and a polypeptide derived from the N terminus of ERFE was sufficient to cause hepcidin supp

164 formational rearrangements must occur in the N terminus of FepA during FeEnt transport.

165 this study, a highly conserved region in the N terminus of FMDV capsid protein VP2 (VP2N) was charact

166 acid substitutions or duplications near the N terminus of G9 were enriched because of their ability

167 The N terminus of gp120, which is gripped by gp41 in the pre

168 The polar region (PR) at the N terminus of gp41 comprises 17 residues, including 7 po

169 create a polyglutamine (polyQ) tract at the N terminus of HTT that expands above a critical threshol

170 onic interaction that ensues between the new N terminus of I16 and the side chain of the highly conse

171 stence of 2 docking sites for PC1 within the N terminus of Kv4.3, supporting a physical interaction.

172 The N terminus of mature TDH comprises a T3SS signal sequenc

173 The N terminus of MinD, including residue Arg 3, which is ne

174 ween the chromoshadow domain of Chp2 and the N terminus of Mit1.

175 s that reveal ligand-induced ordering of the N terminus of Mycobacterium tuberculosis ATR, which orga

176 sociated protein MAP1B binds the cytoplasmic N terminus of Na(v)1.6, and this interaction is disrupte

177 The N terminus of Ndc80, including a 27-residue sequence and

178 The N terminus of NOCT is necessary and sufficient to confer

179 ormations displaying open channel pores, the N terminus of one subunit of the channel tetramer sticks

180 tions, Lgmn cleaved within the extracellular N terminus of PAR(2) at Asn(30) Arg(31), proximal to the

181 Five amino acids at the N terminus of PEAMTs are shown to each be critical for t

182 roteasome system in a response requiring the N terminus of PIF5.

183 chemical shifts of residues residing at the N terminus of SET, preventing its dimerization or oligom

184 mation with Cys-18, a residue present at the N terminus of SIRT6 but absent from other isoforms, indu

185 nd to contact each other through the soluble N terminus of TatC and the interhelical linker region ar

186 ons when stop codons are introduced near the N terminus of the ATI or large truncations are made at t

187 ively charged ribosome-binding domain in the N terminus of the betaNAC subunit (N-betaNAC) as a major

188 ssical nuclear localization sequences in the N terminus of the CLK1 isoform were identified, but thei

189 ducing (GAIN) domain that is proximal to the N terminus of the G protein-coupling seven-transmembrane

190 d cloned viruses revealed mutations near the N terminus of the G9 open reading frame but none in A16

191 n-frame deletion to contain an HA tag at the N terminus of the large UNC-89 isoforms.

192 that results in an alanine expansion at the N terminus of the PABPN1 protein.

193 tation (p.Arg21Cys) has been reported in the N terminus of the protein.

194 mall protein domains, the CC-domains, at the N terminus of the RECK protein, play essential roles in

195 o truncations and mutations in the conserved N terminus of the Rubisco large subunit.

196 As such, the function of the N terminus of this large protein remains poorly characte

197 truncation of the putatively autoregulatory N terminus of TMEM165.

198 (E) and leucine (L)-rich (TEL) patch and the N terminus of TPP1-oligosaccharide/oligonucleotide-bindi

199 tation caused a conformational change in the N terminus of transmembrane residues 22-31 that ultimate

200 bind conserved phosphorylation sites in the N-terminus of 53BP1.

201 the central and C-terminal regions, with the N-terminus of Abeta accommodated by the oligomers as an

202 evidence has accumulated that implicates the N-terminus of Abeta as a region that may initiate the fo

203 f Abeta, which bear "tails" derived from the N-terminus of Abeta.

204 indicated that the charge at the "unfolding" N-terminus of ADH decreased at high in-source activation

205 from radical a-ions produced by UVPD at the N-terminus of ADH.

206 These results revealed that the N-terminus of alpha-syn inserts into the membrane and sp

207 f yellow fluorescent protein attached at the N-terminus of an acetyl H3K9-specific scFv, tethered to

208 Solvent exposure of the N-terminus of aSyn occurs upon release of C-terminus int

209 mice expressing the transcriptionally active N-terminus of ATF6alpha or ATF6beta revealed that these

210 , we show in vitro that UBE2W can modify the N-terminus of both alpha-synuclein and a tau tetra-repea

211 g specific inhibitory phosphorylation in the N-terminus of CDC20.

212 es nine serine residues clustered within the N-terminus of Cse4.

213 We discover that the N-terminus of FMRP directly binds to a phosphorylated se

214 NatE co-translationally acetylates the N-terminus of half the proteome to mediate diverse biolo

215 ZZ domain of ZZEF1 (ZZEF1(ZZ2)) binds to the N-terminus of histone H3 and is capable of accommodating

216 protein with exendin-4 peptide placed at the N-terminus of human alpha-1 antitrypsin, and is named EA

217 Further, we found the N-terminus of Kir6.2 inserted within the central cavity

218 zer of MEILB2 by binding to an alpha-helical N-terminus of MEILB2 and preventing MEILB2 self-associat

219 The N-terminus of MOV10 also leads to increased RGG box-depe

220 The N-terminus of MOV10 is required for this protection: its

221 s a metal-dependent exonuclease and that the N-terminus of MrfB is required for interaction with MrfA

222 ioether-bridged rings, rings A and B, at the N-terminus of nisin.

223 propose that autoproteolytic cleavage of the N-terminus of PC-1, a hotspot for ADPKD mutations, produ

224 onoclonal antibodies are conjugated with the N-terminus of pH low insertion peptide so that they will

225 Here we studied the N-terminus of Pol IV's largest subunit, NRPD1.

226 yme, Dcp2, participates in repression by the N-terminus of Pumilio.

227 n plays an important role by stabilizing the N-terminus of RAS upon excision of the iMet.

228 hosphosites within the acidic and disordered N-terminus of Set2p affect H3K36 methylation levels in v

229 sm of StII(1-30), a peptide derived from the N-terminus of sticholysin II (StII).

230 in-binding site of cardiac leiomodin and the N-terminus of striated muscle tropomyosin.

231 ere, we present the crystal structure of the N-terminus of TBC1D23 (D23N), which consists of both the

232 bosomes pause in the sequence coding for the N-terminus of the envelope protein, immediately downstre

233 the BC-loop) and a potential paratope at the N-terminus of the heavy chain.

234 nvolves the single alpha-helix region at the N-terminus of the IC, in Drosophila and yeast ICs the re

235 Mounting the CRX-527 ligand at the N-terminus of the model peptide antigen delivered a vacc

236 ent where early interactions between the far N-terminus of the peptide and SecR ECL2 likely occur fol

237 epitope within vancomycin was mapped to the N-terminus of the peptide chain, distinct from the bindi

238 k chemistry is highly chemoselective for the N-terminus of the peptide with a C-terminal aldehyde.

239 cluster of threonine residues located in the N-terminus of the protein, which can be phosphorylated b

240 (HBR), located near the myristoylated (Myr) N-terminus of the protein.

241 emonstrated that the AH motif located at the N-terminus of the sequence is involved in cell-Ambn adhe

242 e propose that there is a dual degron at the N-terminus of the UmuD protein in Synechocystis sp. PCC6

243 netrating peptide (cR(10)) conjugated to the N-terminus of ubiquitin via a disulfide linkage to deliv

244 onstrate that the first 19 residues from the N-terminus of UmuD (Sug(1-19) ) fused to a reporter prot

245 additional stretch of ~919 amino acid at the N-terminus of unknown function.

246 PKA phosphorylation of cMyBP-C's N terminus on 3 conserved serine residues is hierarchica

247 a one or more mechanisms involving the EcR's N terminus or the RNA sequence that encodes it.

248 d Abeta peptides with a pyroglutamate at the N-terminus (pGlu3, pE3), are attractive antibody targets

249 he RNA motif was bound by the ZC3H12B's PilT N terminus (PIN) RNase domain, revealing a potential mec

250 s lines harboring missense mutations in this N-terminus produce wild-type (WT) levels of NRPD1, which

251 Segregated charged regions within the RNF4 N-terminus promote compaction, juxtaposing RING domain a

252 binant version of the Candida albicans rAls3 N-terminus protein (rAls3p-N) in aluminum hydroxide.

253 found positioning of the chemokine proximal N-terminus provides a structural explanation of CXC rece

254 Although it is known that the tip of the N-terminus reaches deep into the central cavity, the con

255 kinetic value of 13.4 +/- 0.1 nM through the N-terminus region of cMLCK unique to cardiac-isoform.

256 gs, often covalently bound to the disordered N-terminus region of the peptide, with the assumption th

257 Free SP gives NMR signals from its acidic N-terminus (residues 1-40) and basic C-terminus (residue

258 it of dynactin, the p150(Glued), contains an N-terminus segment that is responsible for the MT-bindin

259 e identity of the fourth amino acid from the N terminus, showing a strong preference for large hydrop

260 e find that the first six amino acids of the N-terminus spontaneously enter the central cavity in an

261 suggested that by interacting with the TatC N terminus, TatB improves the formation of a proficient

262 ntains four methionine residues close to the N terminus that can act as alternative translation initi

263 y molecular mimicry and has a motif near the N terminus that is conserved in IkappaBalpha, beta-caten

264 Mutations in the ARF N terminus that reduced binding also reduced GAP activit

265 All HRPs have a PWWP domain at the N-terminus that binds both histone and DNA substrates.

266 -catenin with a preserved hypophosphorylated N-terminus that interacted with nuclear TCF-4 resulting

267 jugated to either triantennary GalNAc at the N-terminus (the branched architecture) or monomeric GalN

268 The dimer interface of Ste2 is formed by the N terminus, the transmembrane helices H1, H2 and H7, and

269 between EZH2, the nucleosomal DNA and the H3 N-terminus therefore creates the geometry that permits a

270 ransiently threads the Rubisco large subunit N terminus through the axial pore of the AAA+ hexamer.

271 LCCBs act on the STIM N terminus to cause STIM relocalization to junctions and

272 d an unexpected contribution of the receptor N terminus to chemokine signaling.

273 PAR4 is activated by proteolysis of the N terminus to expose a tethered ligand.

274 slocate through the porin, enabling the ColN N terminus to localize within the lumen of an OmpF subun

275 The binding of troponin T's N terminus to the actin-mutant tropomyosin complex was a

276 l-length cAMP-bound form reveals the sensory N-terminus to be a domain-swapped variant of the cNMP/CR

277 echanistically, Pak1 phosphorylates the Mid1 N-terminus to promote its association with cortical node

278 te (PIP(2)), directly interacts with the DAT N-terminus to support DA efflux in response to AMPH.

279 rved across the Dio family anchor the loop's N-terminus to the active site Ser-Cys-Thr-Sec sequence.

280 the orientation of CTCF motifs presents the N-terminus towards cohesin as it translocates from the i

281 with E60X- and G542X-CFTR, although abundant N-terminus truncated proteins due to reinitiation of tra

282 Surprisingly, interactions at the peptides N terminus up to and including MHCII position one (P1) a

283 PALB2 N-terminus variants p.P8L [c.23C>T], p.Y28C [c.83A>G], a

284 bunit EZH2 to nucleosomal DNA orients the H3 N-terminus via an extended network of interactions to pl

285 A nonconserved extended N terminus was also observed in several short-chain dehy

286 FP-CENH3 demonstrated that CENH3-Thr4 in the N-terminus was needed for the deposition as a positive p

287 Using [Delta17]ARF1, lacking the N terminus, we found that PIP(2) has little effect on AS

288 cetylation and phosphorylation of the CURT1B N terminus were mutually exclusive.

289 crease also required an intact intracellular N terminus, which contains the binding motif for endogen

290 terminal WD40 domain of REL2 rather than the N terminus, which is known to bind LxLxL EAR motifs.

291 rule and directly interacts with the SUB1A-1 N terminus, which may explain the enhanced stability of

292 tes binding of ASAP1's PH domain to the ARF1 N terminus, which may partially regulate GAP activity.

293 C/C controls Mps3 degradation through Mps3's N terminus, which resides in the nucleoplasm and possess

294 hrough direct phosphorylation of Cdh1 at its N-terminus, which disrupts the interaction between Cdh1

295 through a conserved HP1-binding motif in its N-terminus, which in turn leads to the recruitment of KA

296 vity were identified: (i) nsP1 tagged at its N terminus with enhanced green fluorescent protein; (ii)

297 at although the interaction of the chemokine N terminus with the receptor-binding pocket is the key d

298 c acid (Aib) residues, were protected at the N-terminus with a carboxybenzyl group (Z) and at the C-t

299 gene through mRNA editing, W shares a common N-terminus with P and V but has a unique C-terminus.

300 O-glycopeptides modified exclusively at the N-terminus would enable O-glycoproteomic methods to rely