ライフサイエンスコーパス: NF-E2-related factor 2

1 We found that GCH1 was regulated by NF-E2-related factor 2, a key mediator of the cellular a

2 s and isolated in useful RCYs, including the NF-E2-related factor 2 activator DDO-7263.3-Phenyl-5-(4-

3 nitiated by amniotic fluid via activation of NF-E2-related factor 2 and identified Sprr2d and Sprr2h

4 ed the synthesis of the transcription factor NF-E2-related factor 2 and phase 2 antioxidant enzymes s

5 ression of NRF2 (nuclear factor erythroid 2 [NF-E2]-related factor 2) and its target enzymes and prot

6 g to identify the transcription factor Nrf2 (NF-E2 related factor 2) as a susceptibility gene in a mu

7 however, a dominant-negative mutant of Nrf2 (NF-E2-related factor 2) blocked this event.

8 Nrf2 (NF-E2-related factor 2) contributes to the maintenance o

9 NF-E2-related factor-2-deficient T cells exhibit a bigge

10 of this study illustrate the key role of the NF-E2-related factor 2/GCH1/BH4 axis during radiation-in

11 Nrf2 (NF-E2-related factor 2) is a central transcription facto

12 Nrf2 (NF-E2-related factor 2) is a nuclear transcription facto

13 ly, we identified GCH1 as a key effector for NF-E2-related factor 2-mediated protection against radia

14 xy-2'-hydroxychalcone, induced both a potent NF-E2-related factor 2-mediated transcriptional response

15 of the redox-sensitive transcription factor NF-E2 related factor 2 (Nrf2) affords protection against

16 ression analysis indicated downregulation of NF-E2 related factor 2 (Nrf2) and its downstream genes i

17 NF-E2 related factor 2 (Nrf2) is a CNC/b-zip protein tha

18 e by multiple approaches that one candidate, NF-E2 related factor 2 (Nrf2), is an inhibitor of Fas-in

19 represses antioxidant response element (ARE)/NF-E2 related factor 2 (Nrf2)-mediated transcriptional r

20 Nf-E2 related factor-2 (Nrf2) is a basic leucine zipper

21 Erythroid 2p45 (NF-E2)-related factor 2 (Nrf2) is a basic-region leucine

22 es by activation of the transcription factor NF-E2-related factor 2 (Nrf2) and its target genes.

23 , and signaling of the transcription factors NF-E2-related factor 2 (Nrf2) and NF-kappaB were examine

24 The transcription factor NF-E2-related factor 2 (Nrf2) binds the antioxidant DNA

25 ionally induced upon oxidative stress by the NF-E2-related factor 2 (NRF2) by direct binding to an an

26 NF-E2-related factor 2 (Nrf2) is a basic leucine zipper

27 NF-E2-related factor 2 (Nrf2) is a major cytoprotective

28 NF-E2-related factor 2 (Nrf2) is a major stress-response

29 NF-E2-related factor 2 (Nrf2) is a transcription factor

30 NF-E2-related factor 2 (Nrf2) is an important transcript

31 NF-E2-related factor 2 (Nrf2) is the key transcription f

32 The activation of the transcription factor NF-E2-related factor 2 (Nrf2) maintains cellular homeost

33 f SQSTM1 and DPP3 in IMR-32 cells stimulated NF-E2-related factor 2 (NRF2) nuclear translocation and

34 4002 and wortmannin, significantly decreased NF-E2-related factor 2 (Nrf2) nuclear translocation indu

35 H-associated protein 1 (Keap1) mutations and NF-E2-related factor 2 (Nrf2) pathway activation in EOC

36 gens and CR mimetics induce and activate the NF-E2-related factor 2 (Nrf2) pathway.

37 The transcription factor NF-E2-related factor 2 (Nrf2) plays an essential role in

38 NF-E2-related factor 2 (Nrf2) regulates expression and c

39 Transcription factor NF-E2-related factor 2 (Nrf2) regulates the induction of

40 NF-E2-related factor 2 (NRF2) transcription factor has a

41 NF-E2-related factor 2 (Nrf2) transcription factor regul

42 The transcription factor NF-E2-related factor 2 (Nrf2) translocates into the nucl

43 all of these genes contain binding sites for NF-E2-related factor 2 (NRF2), a major regulator of the

44 We have reported that disruption of NF-E2-related factor 2 (Nrf2), a master transcription re

45 NF-E2-related factor 2 (Nrf2), a member of the Cap'n'Col

46 NF-E2-related factor 2 (Nrf2), a redox sensitive factor,

47 molecule prompted us to study its effects on NF-E2-related factor 2 (Nrf2), a redox-regulated transcr

48 at least in part, to impaired activation of NF-E2-related factor 2 (Nrf2), a transcription factor in

49 ent studies using knockout mice suggest that NF-E2-related factor 2 (Nrf2), along with small Maf prot

50 of antioxidant proteins, including catalase, NF-E2-related factor 2 (Nrf2), and heme oxygenase 1 (HO-

51 FE2L2), a transcription factor also known as NF-E2-related factor 2 (Nrf2), is a key cytoprotective g

52 as the thioredoxin system, glutathione, and NF-E2-related factor 2 (Nrf2), little is known about the

53 A basic leucine zipper transcription factor, NF-E2-related factor 2 (Nrf2), plays a critical role in

54 e stabilization and nuclear translocation of NF-E2-related factor 2 (Nrf2), where it binds to the ant

55 and upregulation of the transcription factor NF-E2-related factor 2 (Nrf2), which controls cellular a

56 ecies generation and subsequent induction of NF-E2-related factor 2 (NRF2)-dependent antioxidant gene

57 Male Sprague-Dawley rats and wild-type and NF-E2-related factor 2 (Nrf2)-null mice were subjected t

58 mily member, acts as a negative regulator of NF-E2-related factor 2 (Nrf2).

59 ments that can bind the transcription factor NF-E2-related factor 2 (Nrf2).

60 (NRP/B) was colocalized and interacted with NF-E2-related factor 2 (Nrf2).

61 otein 1 (Keap1) and the transcription factor NF-E2-related factor 2 (Nrf2).

62 h increased expression of genes regulated by NF-E2-related factor 2 (Nrf2)/antioxidant response eleme

63 NF-E2-related factor 2 (NRF2; also called NFE2L2) and re

64 NF-E2-related factor-2 (Nrf2) activators promote cellula

65 idase 4 (NOX4) and induced the activation of NF-E2-related factor-2 (NRF2) and its downstream effecto

66 /3 and HDAC-5/7, respectively) in regulating NF-E2-related factor-2 (Nrf2) and Kruppel-like factor-2

67 of the present study was to investigate how NF-E2-related factor-2 (Nrf2) and phosphatidylinositol 3

68 Activation of the transcription factor NF-E2-related factor-2 (Nrf2) by sulforaphane, a natural

69 NF-E2-related factor-2 (Nrf2) is a key regulator of redo

70 PERK-dependent activation of NF-E2-related factor-2 (Nrf2) is critical for survival s

71 lso determined that the transcription factor NF-E2-related factor-2 (Nrf2) is involved in the specifi

72 In this study, we demonstrate that NF-E2-related factor-2 (Nrf2) plays a major role in tran

73 NF-E2-related factor-2 (Nrf2) regulates the gene express

74 and a reduction in the nuclear expression of NF-E2-related factor-2 (Nrf2) that down-regulate the exp

75 hane is an activator of transcription factor NF-E2-related factor-2 (nrf2) that regulates gene expres

76 1; Hmox1) system through the redox-regulated NF-E2-related factor-2 (Nrf2) transcription factor, but

77 The transcription factor NF-E2-related factor-2 (Nrf2), a master regulator of thi

78 nd its binding partner, transcription factor NF-E2-related factor-2 (NRF2), are chemoprevention targe

79 r of antioxidant genes, transcription factor NF-E2-related-factor-2 (Nrf2), is repressed by epigeneti

80 The Nrf2 (nuclear factor erythroid 2 [NF-E2]-related factor 2 [Nrf2])-Keap1 (Kelch-like erythr

81 Here we show that the Drosophila Nrf2 (NF-E2-related factor 2) ortholog CncC (cap 'n' collar is

82 ld-type mice, mice lacking the expression of NF-E2-related factor-2, the transcription factor that re

83 g regulates ROS through transcription factor NF-E2-related factor 2, which is important for intestina

84 el of a key antioxidant transcription factor NF-E2-related factor 2, which resulted in accumulation o