ライフサイエンスコーパス: NGU

1 NGU was considered idiopathic when Neisseria gonorrhoeae

2 NGU was defined as >=5 polymorphonuclear leukocytes per

3 trachomatis was detected in 36 (30%) of 121 NGU case patients and in 4 (3%) of 117 control subjects

4 . genitalium was detected in 27 (22%) of 121 NGU case patients and in 5 (4%) of 117 control subjects

5 We analyzed data from an NGU treatment trial among symptomatic heterosexual men a

6 d associations between urethral bacteria and NGU in men who have sex with men (MSM) and men who have

7 tify associations between bacterial taxa and NGU and to select bacteria for targeted qPCR.

8 tify associations between bacterial taxa and NGU, and to select bacteria for targeted quantitative PC

9 ma genitalium during initial evaluations for NGU and (2) switching from azithromycin to doxycycline a

10 The incubation period for NGU caused by Mycoplasma genitalium is probably longer t

11 Clinical and microbiologic cure rates for NGU were somewhat low and there was no significant diffe

12 lasma genitalium is probably longer than for NGU caused by C. trachomatis.

13 Urine was collected from NGU cases (129 MSM, 121 MSW) and controls (70 MSM, 114 M

14 Urine was collected from NGU cases (129 MSM; 121 MSW) and controls (70 MSM; 114 M

15 iations were stronger in men with idiopathic NGU.

16 prevalence was 14.7% (95% CI, 7.8%-21.6%) in NGU cases.

17 om azithromycin to doxycycline as first-line NGU treatment.

18 enitalium is a frequent undiagnosed cause of NGU in this population with rates of macrolide resistanc

19 s a role of this organism in the etiology of NGU.

20 d be modified to reduce treatment failure of NGU and the development of further resistance.

21 l resistance testing in men with symptoms of NGU as well as in their current sexual partner(s).

22 h were associated with signs and symptoms of NGU.

23 hese data have implications for treatment of NGU and control of trichomoniasis.

24 Persistent CT and MG after treatment of NGU are common, and were associated with clinical findin

25 r routine testing and empirical treatment of NGU should be modified to reduce treatment failure of NG

26 about single-dose azithromycin treatment of NGU, and emphasizing that NGU treatment should be guided

27 are diagnosis of N. gonorrhoeae infection or NGU in men, meatal swabs should be avoided in the absenc

28 Mycoplasma genitalium and other NGU pathogens were detected using nucleic acid amplifica

29 Men with persistent NGU received moxifloxacin 400 mg for 14 days.

30 The clinical characteristics of symptomatic NGU have not been shown to identify the pathogen specifi

31 mycin treatment of NGU, and emphasizing that NGU treatment should be guided by etiologic diagnosis.

32 lium, which also commonly causes undiagnosed NGU, necessitates treatment with macrolides or fluoroqui

33 ts for persistent non-gonococcal urethritis (NGU) were significantly lower (odds ratio: .4; 95% confi

34 biotic therapy for nongonococcal urethritis (NGU) and cervicitis is aimed at Chlamydia trachomatis, b

35 a common cause of nongonococcal urethritis (NGU) and cervicitis.

36 thogens with acute nongonococcal urethritis (NGU) in heterosexual men presenting to an urban sexually

37 um associated with nongonococcal urethritis (NGU) in men and cervicitis, endometritis, and pelvic inf

38 oeae infection and nongonococcal urethritis (NGU) in men.

39 Nongonococcal urethritis (NGU) is a common syndrome with no known etiology in 50%

40 Nongonococcal urethritis (NGU) is a common syndrome with no known etiology in up t

41 he major causes of nongonococcal urethritis (NGU) worldwide but an uncommon sexually transmitted infe

42 nowledged cause of nongonococcal urethritis (NGU), access to diagnostic testing is limited.

43 s) associated with nongonococcal urethritis (NGU).

44 ly associated with nongonococcal urethritis (NGU).

45 onas is a cause of nongonococcal urethritis (NGU); however, studies of its prevalence in men have bee

46 is recommended for nongonococcal urethritis (NGU); recent evidence suggests their efficacy has declin

47 Washington, during the period 2007-2009 with NGU (defined as visible urethral discharge and/or >/=5 p

48 nalyses, detection of HI was associated with NGU among MSM (12% vs 3%, P = .036) and MSW (17% vs 1%,

49 nalyses, detection of HI was associated with NGU among MSM (12% vs. 3%, p=0.036) and MSW (17% vs. 1%,

50 UU was only marginally associated with NGU in aggregate multivariable analyses, irrespective of

51 vs 1%, P < .001), but MP was associated with NGU only among MSM (13% vs 1%, P = .004).

52 vs. 1%, p<0.001), but MP was associated with NGU only among MSM (13% vs. 1%, p=0.004).

53 UP was not positively associated with NGU overall or among subgroups.

54 U. urealyticum was not associated with NGU.

55 Improved outcomes in men with NGU and better antimicrobial stewardship are likely to a

56 Men with NGU received 1 g of azithromycin.

57 e need for diagnostic MG testing of men with NGU to direct therapy.

58 17 control subjects (P<.01), only 3 men with NGU were infected with both C. trachomatis and M. genita

59 d with 182 men without NGU, the 249 men with NGU were more likely to have HI (14% vs 2%) and MP (21%

60 red to 182 men without NGU, the 249 men with NGU were more likely to have HI (14% vs. 2%) and MP (21%

61 In men with NGU, 19.9% were infected with trichomonas.

62 red azithromycin and doxycycline in men with NGU, hypothesizing that azithromycin was more effective

63 e (DOX) against M. genitalium among men with NGU.

64 to assess the associations of UU and UP with NGU.

65 lyticum (UU) and Ureaplasma parvum (UP) with NGU using 2 separate control groups.

66 The absence of an association of UU with NGU among men with more lifetime sex partners suggests t

67 diseases clinic in Seattle, Washington, with NGU (visible urethral discharge or >/=5 polymorphonuclea

68 department (ED) attendees (n = 193) without NGU.

69 ithin a cohort study of men with and without NGU attending an urban sexually transmitted diseases cli

70 Compared to 182 men without NGU, the 249 men with NGU were more likely to have HI (1

71 Compared with 182 men without NGU, the 249 men with NGU were more likely to have HI (1