ライフサイエンスコーパス: PGM

1 PGM and bPGM are key catalysts of glycolysis that have b

2 PGM binding was within 75-149 amino acids (aa) of Pak1,

3 PGM mRNA was detectable by RNA-blot analysis in all tiss

4 PGM plants showed low pollen production and overall low

5 PGM plays a central role in the glycolytic pathway at th

6 PGM-free Fe-N-C electrocatalysts now exhibit ORR activit

7 PGM-RP is expressed predominantly in muscle with the hig

8 PGM-RP is therefore a good marker of the contractile/dif

9 PGMs were evaluated in 127 genes from 6 major DNA repair

10 users versus 19% in low users (P < or =.05; PGM and WM, not significant).

11 ressor of T-cell receptor signaling-1 (Sts-1 PGM) protein.

12 enzymatic activity of phosphoglucomutase 1 (PGM), an important regulatory enzyme in cellular glucose

13 s are altered to their counterparts in Sts-1(PGM) has substantially increased activity.

14 glycerate mutase-like domain of Sts-1 (Sts-1(PGM)) has a potent phosphatase activity that contributes

15 of Sts-2(PGM) is remarkably similar to Sts-1(PGM), including conservation of all catalytic residues.

16 ity of the correspondent Sts-1 domain, Sts-1(PGM), is key for its ability to negatively regulate the

17 u) cm(-2) capable of achieving 7.4 W mg(-1) (PGM) as well as supporting a current of 0.7 A cm(-2) at

18 In this study, we analyze 10 PGM protein haplotypes with respect to PGM activity, the

19 Overall, our data demonstrate that Sts-2(PGM) adopts the conformation of an active phosphatase wh

20 The function of Sts-2(PGM) as a phosphatase has been less clear, principally b

21 ylated substrates, we demonstrate that Sts-2(PGM) has clear, albeit weak, phosphatase activity.

22 e, we present the crystal structure of Sts-2(PGM) in the phosphorylated active form and bound to VO(3

23 The crystal structure of Sts-2(PGM) is remarkably similar to Sts-1(PGM), including cons

24 arkably similar to the one seen in apo-Sts-2(PGM) suggesting that the spatial arrangement of the cata

25 increases the phosphatase activity of Sts-2(PGM) toward model substrates.

26 s specificity determinants, in that an Sts-2(PGM) triple mutant in which these three amino acids are

27 e activity of the PGM domain of Sts-2, Sts-2(PGM).

28 We identified 538 PGMs in 98 DRGs (POLG, MUTYH, ERCC2, and BRCA2, among ot

29 =.05) in all regions: r = 0.79 (AGM), 0.57 (PGM), and 0.76 (WM).

30 a Glc-1-P uridylyltransferase (cps3U) and a PGM homologue (cps3M) are present in the type 3 capsule

31 The function of this gene product as a PGM was demonstrated through enzymatic and complementati

32 he challenges to be overcome in developing a PGM-based biosensor and bring it to market.

33 for 24 h, along with reduced synthesis of a PGM identified as a 67-kD phosphoprotein on two-dimensio

34 reviews the published methods to repurpose a PGM to detect analytes other than glucose, and analyses

35 These observations reveal a PGM/AcP-like enzyme activity involved in the control of

36 clinical lab tests into POC tests that use a PGM.

37 0.6 V at 0.6 A cm(-2) under H(2) /air with a PGM loading <0.125 mg cm(-2) with AEMFCs for the first t

38 feine reduced CBF (P < or =.05) by 23% (AGM, PGM) and 18% (WM) in all subjects.

39 Two classes of phosphoglucomutases (alpha-PGM and beta-PGM) are distinguished on the basis of thei

40 nce, yet few studies have addressed alphaPMM/PGM inhibition from this important Gram-negative bacteri

41 s will enhance the design of future alphaPMM/PGM inhibitors.

42 sphomannomutase/phosphoglucomutase (alphaPMM/PGM) from P. aeruginosa is involved in bacterial cell wa

43 ential time-dependent or reversible alphaPMM/PGM inhibitors.

44 GM catalysts), and 2) to develop alternative PGM-free catalysts.

45 find a twofold difference in activity among PGM protein haplotypes that is associated with a threefo

46 l technoeconomic model of substitution among PGMs within the automotive sector (the largest user of P

47 plored as a promising replacement for Fe and PGM catalysts.

48 passengers was heterozygous for both FVL and PGM.

49 ensive direct interactions between GAPDH and PGM.

50 Pak1 and PGM were colocalized in model cell systems and showed fu

51 rial concepts and development of low-PGM and PGM-free catalysts are discussed.

52 understanding the degradation of low-PGM and PGM-free catalysts in fuel cell MEAs and materials-based

53 nzyme assay, we have identified both PMM and PGM activity from one of these genes, Rv3257c (MtmanB).

54 three-dimensional structure of B. anthracis PGM is composed of two structural and functional domains

55 from Escherichia coli but had little if any PGM activity and gave no detectable PGM activity in B. s

56 Beta-PGM conserves the core domain catalytic scaffold of the

57 beta-PGM is a member of the haloacid dehalogenase (HAD) super

58 beta-PGM is unusual among family members in that the common p

59 n X-ray crystal structure of the Mg(2+)-beta-PGM complex is examined in the context of previously rep

60 e, the three-dimensional structure of a beta-PGM and the first view of the true phosphoenzyme interme

61 s of phosphoglucomutases (alpha-PGM and beta-PGM) are distinguished on the basis of their specificity

62 -PGM activation by the Mg(2+) cofactor, beta-PGM activation by Asp8 phosphorylation, and the role of

63 In this paper, we examine beta-PGM activation by the Mg(2+) cofactor, beta-PGM activati

64 tal-binding loop in Mg(2+) anchoring in beta-PGM is consistent with the relatively loose binding indi

65 vidence that the autophosphorylation of beta-PGM by the substrate beta-G1P accounts for the origin of

66 rt a substrate induced-fit mechanism of beta-PGM catalysis, which allows phosphomutase activity to do

67 ons of ground-state analog complexes of beta-PGM involving trifluoroberyllate establish that when the

68 The active site of beta-PGM is located between the core and the cap domain and i

69 er, the trifluoroberyllate complexes of beta-PGM provide a picture of how the enzyme is able to organ

70 Kinetic analyses of the specificity of beta-PGM toward phosphoryl group donors and the specificity o

71 he Mg(2+)-alpha-d-galactose-1-phosphate-beta-PGM, Mg(2+)-phospho-beta-PGM, and Mg(2+)-beta-glucose-6-

72 -G1P accounts for the origin of phospho-beta-PGM in the cell.

73 p donors and the specificity of phospho-beta-PGM toward phosphoryl group acceptors were carried out.

74 se-1-phosphate-beta-PGM, Mg(2+)-phospho-beta-PGM, and Mg(2+)-beta-glucose-6-phosphate-1-phosphorane-b

75 ococcus lactis beta-phosphoglucomutase (beta-PGM) catalyzes the interconversion of beta-d-glucose 1-p

76 phosphorylated beta-phosphoglucomutase (beta-PGM) from Lactococcus lactis has been determined to 2.3

77 e complexes of beta-phosphoglucomutase (beta-PGM) have demonstrated the importance of charge balance

78 Tauhe beta-phosphoglucomutase (beta-PGM) of the haloacid dehalogenase enzyme superfamily (HA

79 -beta-glucose-6-phosphate-1-phosphorane-beta-PGM complexes to identify conformational changes that oc

80 nd to the active site of phosphorylated beta-PGM in such a way as to position the C(1)OH near the pho

81 he mechanism by which hydrolysis of the beta-PGM phospho-Asp8 is avoided during the time that the act

82 nd the failure to detect differences between PGM allozymes in functional studies.

83 Both PGM catalysts were thoroughly studied in membrane electr

84 the range of targets that can be detected by PGMs, we report here the use of antibodies in combinatio

85 can expand the range of target detection by PGMs significantly.

86 ts in the sample and the glucose measured by PGMs.

87 le biosynthesis is derived from the cellular PGM.

88 that outperforms synthesized and commercial PGM catalysts for CO oxidation in simulated exhaust stre

89 Earlier studies of the common PGM allozymes in Drosophila melanogaster reported no in

90 has been made in the development of low-cost PGM-free electrocatalysts synthesized from inexpensive,

91 Aside from their high cost, PGM catalysts struggle with CO oxidation at low temperat

92 hat the cDNAs encode the two known cytosolic PGM isozymes, PGM1 and PGM2.

93 educed amino acid sequences of the cytosolic PGMs contain the conserved phosphate-transfer catalytic

94 The cytosolic PGMs of maize are distinct from a plastidic PGM of spina

95 strategies have been pursued: 1) to decrease PGM catalyst usage (so-called low-PGM catalysts), and 2)

96 e if any PGM activity and gave no detectable PGM activity in B. subtilis.

97 A number of recently discovered PGM-like proteins in a variety of organisms have been pr

98 24 normal and 20 tumor-bearing rats, Gd-DTPA PGM was administered intravenously in doses of 2, 10, 20

99 provide new insight into designing efficient PGM-free electrodes with improved performance and durabi

100 ed two maize (Zea mays L.) cDNAs that encode PGM with 98.5% identity in their deduced amino acid sequ

101 e mutase/bisphosphoglycerate mutase enzymes (PGM/bPGM; EC 5.4.2.1/5.4.2.4).

102 EPPase PGM shows limited substrate specificity with an ability

103 The putative EPPase PGM active site contains signature residues shared by 2H

104 ing site of known prokaryotic and eukaryotic PGMs.

105 s witnessed remarkable progress in exploring PGM-free cathode catalysts for the oxygen reduction reac

106 of the contractile phenotype) also expressed PGM-RP.

107 The high-performance atomic Fe PGM-free catalyst holds great promise as a replacement f

108 xplain the absence of latitudinal clines for PGM allozyme alleles, the lack of association of PGM all

109 here is, surprisingly, no candidate gene for PGM.

110 mes, with residues known to be important for PGM/AcP catalytic activity conserved in nature and posit

111 edstocks, efficient separation processes for PGM recovery and purification are needed.

112 us data, suggest that any potential role for PGM-like proteins in regulated exocytosis is unlikely to

113 ctive and durable platinum group metal-free (PGM-free) catalysts and electrodes.

114 Platinum group metal-free (PGM-free) metal-nitrogen-carbon catalysts have emerged a

115 he development of platinum group metal-free (PGM-free) oxygen reduction reaction (ORR) catalysts for

116 s of the same species was also obtained from PGM.

117 Studies of future PGM flows have focused on trends within material flows o

118 e total Pt content per kW of power (<0.125 g(PGM)/kW) at cell potential 0.65 V: a value of 0.15 g(Pt)

119 ctor V Leiden (FVL) and prothrombin G20210A (PGM), which predispose to venous thromboembolism.

120 tion GM (AGM), and posterior circulation GM (PGM).

121 enzymes and all other PGM-like proteins have PGM activity.

122 Pgm amino acid polymorphisms show that high PGM activity, and apparently higher flux to glycogen syn

123 We have sequenced 1.8 kb of the human PGM-RP promoter and shown that it lacks a conventional T

124 o assess AMD severity and hyperpigmentation (PGM) presence.

125 and eukaryotic mutases are not conserved in PGM-RP, a finding consistent with the lack of enzymatic

126 xocytosis, but showed a dramatic decrease in PGM activity.

127 Herein, recent developments in PGM-free electrocatalysis, demonstrating increased fuel-

128 A 2-fold increase in PGM activity enhances glycolytic flux, allows indefinite

129 A reduction in PGM mRNA accumulation was detected in roots deprived of

130 ing number of cytoplasmic proteins including PGM-RP remains to be explored.

131 ely on threonine 466 significantly increased PGM enzymatic activity and could be blocked by transfect

132 s of Bacillus anthracis cofactor-independent PGM (iPGM).

133 tructure of a diphosphoglycerate-independent PGM to be determined.

134 Stable transfection of PGM into PGM-deficient K562 leukemia cells further demonstrated t

135 edlings, distinct from the pathway involving PGM.

136 niquely, T. brucei has been able to lose its PGM gene.

137 ysis suggests that several of these may lack PGM enzymatic activity.

138 Insertion mutants that lacked PGM activity were avirulent in both immunologically norm

139 o decrease PGM catalyst usage (so-called low-PGM catalysts), and 2) to develop alternative PGM-free c

140 ing material concepts and development of low-PGM and PGM-free catalysts are discussed.

141 ress in understanding the degradation of low-PGM and PGM-free catalysts in fuel cell MEAs and materia

142 of the Ion Torrent Personal Genome Machine (PGM) in food traceability analyzing candies as a model o

143 ing the Ion Torrent Personal Genome Machine (PGM).

144 on the Ion Torrent Personal Genome Machine (PGM).

145 3,4,6-penta- O-galloyl-beta-d-mannopyranose (PGM)), with mannose as central core and galloyl substitu

146 Phase gradient metagratings (PGMs) have provided unprecedented opportunities for wave

147 Platinum group metal (PGM) catalysts are the current standard for control of p

148 Whether the alternative Pt group metal (PGM) catalysts can exhibit such high performance is an i

149 d challenge to replace platinum group metal (PGM) catalysts with earth-abundant materials for the oxy

150 excess of 2X that of a platinum group metal (PGM) three way catalytic converter.

151 xposed active sites of platinum group metal (PGM)-based materials is an efficient way to improve thei

152 the possibility to use platinum group metal (PGM)-free electrocatalysts and cheaper membranes, ionome

153 M-N-C) are the leading platinum group metal (PGM)-free electrocatalysts for the oxygen reduction reac

154 on (M-N-C) moieties as platinum group metal (PGM)-free electrocatalysts in proton-exchange membrane f

155 Developing low platinum-group-metal (PGM) catalysts for the oxygen reduction reaction (ORR) i

156 is the high content of platinum-group-metal (PGM) electrocatalysts required to perform the sluggish o

157 brane (PEM) fuel cell, platinum-group-metal (PGM)-based catalysts account for ~50% of the projected t

158 i, Mn) are the popular platinum group-metal (PGM)-free catalysts for many electrochemical reactions.

159 rmance and inexpensive platinum-group-metal (PGM)-free catalysts for the oxygen reduction reaction (O

160 tegration of efficient platinum-group-metal (PGM)-free catalysts to fuel cells and electrolyzers is a

161 technical target for total Pt group metals (PGM) loading.

162 Platinum group metals (PGMs) are essential for growing energy applications, and

163 Platinum-group metals (PGMs) are technological and economic enablers of many in

164 y in conjunction with platinum group metals (PGMs)(1-9).

165 activities similar to platinum group metals (PGMs), yet TMCs are orders of magnitude more abundant an

166 nstrated the use of personal glucose meters (PGMs) and functional DNAs for the detection of many nong

167 rt a discovery that personal glucose meters (PGMs) can give a dose-dependent response to nicotinamide

168 Personal glucose meters (PGMs) have been used for the measurement of blood glucos

169 port application of personal glucose meters (PGMs), which are widely available, low cost, and simple

170 r a demanding ultralow PGM loading (0.070 mg(PGM) cm(-2)) due to the non-contacting enclosure of grap

171 of particles is termed the phonon gas model (PGM), and it has been used almost ubiquitously to try an

172 g expressions based on the phonon gas model (PGM).

173 ology measurements on porcine gastric mucin (PGM) show that pH elevation by H. pylori induces a drama

174 particles (VLPs) against pig gastric mucin (PGM) using 4 VLPs that represent different GII.4 norovir

175 the known atomic structure of rabbit muscle PGM, suggests that both ciliate enzymes and all other PG

176 thin its C-terminal phosphoglycerate mutase (PGM) homology domain and key for the regulation of TCR s

177 hosphatase (EPPase) phosphoglycerate mutase (PGM) homology domain, the first structure of a steroid p

178 stearothermophilus phosphoglycerate mutase (PGM), which interconverts 2- and 3-phosphoglyceric acid

179 e glycolytic enzyme phosphoglycerate mutase (PGM).

180 Phosphoglycerate mutases (PGMs) catalyze the isomerization of 2- and 3-phosphoglyc

181 Lastly, we evaluated several new PGM technologies in the context of antibody sequencing.

182 So far, no PGM catalyst shows activity for CO oxidation at cryogeni

183 A facile synthesis of non-PGM ORR electrocatalysts through thermolysis of one-pot

184 des." Nevertheless, the specific activity of PGM was not significantly affected in roots deprived of

185 rade off durability for the high activity of PGM-based catalysts.

186 stent with the lack of enzymatic activity of PGM-RP in vitro, and the absence of a phosphorylated int

187 allozyme alleles, the lack of association of PGM allozymes with the cosmopolitan In(3L)P inversion, a

188 milar activity and, conversely, depletion of PGM or glucosephosphate isomerase with short interfering

189 ctivity maps based on kinetic descriptors of PGM-free single-metal-site ORR electrocatalysts can help

190 erstanding the main causes of instability of PGM-free ORR catalysts in acidic environments, focusing

191 Strong direct interaction of PGM with Pak1 but not Pak2, Pak3, or Pak4 was observed.

192 When a strain lacking the major isoform of PGM (pgm2Delta) was grown on media containing galactose

193 epot and (ii) increasing forespore levels of PGM approximately 10-fold in B. subtilis resulted in a l

194 Levels of PGM-RP increased in quiescent PAC1 and A10 cells, and we

195 lacks metavinculin, expressed low levels of PGM-RP.

196 n Glc-1-P and Glc-6-P due to a limitation of PGM enzymatic activity in the pgm2Delta strain.

197 The loss of PGM activity in the insertion mutants also caused growth

198 s approach is able to increase the number of PGM-free active sites.

199 This is the first example in any organism of PGM activity being completely replaced in this way and i

200 Pak1-mediated phosphorylation of PGM selectively on threonine 466 significantly increased

201 kinetic parameters for the ORR reactivity of PGM-free nitrogen-coordinated single-metal M-site carbon

202 hrough its phosphorylation and regulation of PGM activity.

203 ide first insight into the possible roles of PGM/bPGM in plant physiology and in plant-pathogen inter

204 w exhibit ORR activities approaching that of PGM electrocatalysts but at a fraction of the cost, prom

205 Stable transfection of PGM into PGM-deficient K562 leukemia cells further demon

206 n the automotive sector (the largest user of PGMs) reflecting the rational response of firms to chang

207 an facilitate immortalization via effects on PGM levels and glycolysis.

208 ests that both ciliate enzymes and all other PGM-like proteins have PGM activity.

209 olecules herein described, and in particular PGM, might be useful prototypes for the development of n

210 he phosphoglycerate mutase/acid phosphatase (PGM/AcP) family of enzymes, with residues known to be im

211 ents (namely, repeating phosphodisaccharide (PGM), phosphoglycan, phosphosaccharide core-lyso-alkyl-p

212 Phosphoglucomutase (PGM) catalyzes the interconversion of glucose (Glc)-1- a

213 Phosphoglucomutase (PGM) is a key enzyme in glucose metabolism, where it cat

214 Phosphoglucomutase (PGM) is a ubiquitous highly conserved enzyme involved in

215 Glc and is mediated by a phosphoglucomutase (PGM) and a Glc-1-P uridylyltransferase, respectively.

216 mplementation of PMM and phosphoglucomutase (PGM) deficient strains of Pseudomonas aeruginosa, and an

217 samine mutase (PAGM) and phosphoglucomutase (PGM) reversibly catalyse the transfer of phosphate betwe

218 Although the enzyme phosphoglucomutase (PGM) possesses several allozyme polymorphisms, it is uni

219 of the major isoform of phosphoglucomutase (PGM) causes an accumulation of glucose 1-phosphate when

220 The phosphoglucomutase (PGM) and Glc-1-P uridylyltransferase activities necessar

221 is a novel member of the phosphoglucomutase (PGM) family of proteins.

222 PGMs of maize are distinct from a plastidic PGM of spinach (Spinacia oleracea).

223 mination of three ligand-bound states of PMM/PGM harboring a mutation that suppresses activity.

224 Previous structural studies of PMM/PGM have established a key role for conformational chang

225 tional flexibility of different forms of PMM/PGM in solution, including its active, phosphorylated st

226 amic reorientation in the active site of PMM/PGM.

227 e phosphomannomutase/phosphoglucomutase (PMM/PGM) from Pseudomonas aeruginosa catalyzes an intramolec

228 e phosphomannomutase/phosphoglucomutase (PMM/PGM) from Pseudomonas aeruginosa catalyzes the reversibl

229 e phosphomannomutase/phosphoglucomutase (PMM/PGM) from the bacterium Pseudomonas aeruginosa is involv

230 Phosphomannomutase/phosphoglucomutase (PMM/PGM) is a ubiquitous four-domain enzyme that catalyzes p

231 Collective responses of Pseudomonas PMM/PGM to phosphosugar substrates and inhibitor were assess

232 Structural characterization of two PMM/PGM-intermediate complexes with glucose 1,6-bisphosphate

233 revealed the presence of polygamomonoecious (PGM) plants in most populations at a low percentage (~2-

234 specific phosphoglucomutase-related protein (PGM-RP) which is expressed predominantly in adult viscer

235 The PGM-related protein (PGM-RP), which contains 506 amino acids (55.6 kDa), is s

236 The reduced PGM activity of JY1060 resulted in enhanced binding of c

237 In contrast, a mutant (JY1060) with reduced PGM activity was avirulent in the former but had only mo

238 Because wild-type p53 down-regulates PGM, mutation of p53 can facilitate immortalization via

239 demonstrated the role of Pak1 in regulating PGM activity.

240 method opens an attractive avenue to replace PGMs in high energy density applications such as fuel ce

241 Efforts to repurpose PGMs for the detection of any analyte at the point-of-ca

242 ed in a distant gene (pgm) encoding a second PGM homologue.

243 The best studied PGM-like protein is parafusin, a major phosphoprotein in

244 platforms (Illumina HiSeq, Life Technologies PGM and Proton, Pacific Biosciences RS and Roche 454).

245 the model support previous conclusions that PGM use is likely to grow, in some cases strongly, by 20

246 The model also indicates that PGM-demand growth will be significantly influenced by th

247 is study, we make the novel observation that PGM is also involved in the regulation of cellular Ca(2+

248 study of nucleotide variation observed that PGM allozymes are a heterogeneous mixture of amino acid

249 We propose that PGM is a stable protein and that existing levels are suf

250 The results suggest that PGM plays a critical role in pneumococcal virulence by a

251 The PGM-related protein (PGM-RP), which contains 506 amino a

252 The PGM-RP promoter may have acquired negative regulatory el

253 Furthermore, mAb against the PGM reversed (approximately 70%) the effect of LPG.

254 ective, the problem with trying to apply the PGM to amorphous materials is the fact that one cannot r

255 PGM for amorphous materials by assuming the PGM is applicable, and then, using a combination of latt

256 s still has many open questions, because the PGM itself becomes questionable when one cannot rigorous

257 ypothesis of disomic inheritance at both the PGM and slow-PGI loci.

258 tally different way than is described by the PGM.

259 When labeled with Gd-DTPA, the PGM-based graft copolymer significantly increases signal

260 information and species per product from the PGM platform than PCR-CS.

261 he results of this approach show that if the PGM was valid, a large number of the mid and high freque

262 These results demonstrate that most of the PGM activity required for type 3 capsule biosynthesis is

263 versed by changing the integer parity of the PGM design, and such phenomenon is very robust.

264 investigate the phosphatase activity of the PGM domain of Sts-2, Sts-2(PGM).

265 Here, we tested the validity of the PGM for amorphous materials by assuming the PGM is appli

266 key limiting factor, i.e., the nature of the PGM-free active site, are summarized.

267 The organisation of the PGM-RP gene is essentially identical to that of PGM1.

268 This then strongly suggests that the PGM is inapplicable to amorphous solids.

269 ncies between methodologies suggest that the PGM platform is still pre-mature for its use in food tra

270 We propose that the PGM-RP gene, which we have mapped to human chromosome 9q

271 Sequence comparisons suggest that the PGM-RP promoter evolved from the main phosphoglucomutase

272 es binding to endothelial cells, whereas the PGM domain mediates the cell inhibitory effect.

273 2) could be reached at 0.4 V vs RHE with the PGM-free anode, at 25 C.

274 Therefore, PGM is not one of the so-called "anaerobic polypeptides.

275 n of a possible catalytic mechanism for this PGM.

276 talysts as the most promising alternative to PGM catalysts.

277 no acids (aa) of Pak1, while Pak1 binding to PGM was in the N-terminal 96 aa.

278 ze 10 PGM protein haplotypes with respect to PGM activity, thermostability, and adult glycogen conten

279 (2002), but not the Sydney (2012) strain, to PGM.

280 limited geographic availability, has led to PGMs being labeled as "critical materials".

281 a MiSeq (28,886 reads) than with Ion Torrent PGM (1754 reads).

282 or (Roche), MiSeq (Illumina) and Ion Torrent PGM (Life Technologies) are laser-printer sized and offe

283 Unlike the MiSeq, the Ion Torrent PGM and 454 GS Junior both produced homopolymer-associat

284 successfully sequenced using the Ion Torrent PGM and Illumina MiSeq platforms.

285 Run in 100-bp mode, the Ion Torrent PGM had the highest throughput (80-100 Mb/h).

286 s been designed for the benchtop Ion Torrent PGM platform and can be operated with minimal bioinforma

287 mplicon sequencing method on the Ion Torrent PGM platform for targeted resequencing of a panel of six

288 -Seq data were acquired using an Ion Torrent PGM platform.

289 ibody variable domains using the Ion Torrent PGM platform.

290 cing (Illumina HiSeq 2500/MiSeq, Ion Torrent PGM, Pacific Biosciences RS) are allowing for previously

291 eq provides higher coverage than Ion Torrent PGM.

292 emblies projects sequenced using Ion Torrent PGM.

293 node catalyst, to create AEMFCs with a total PGM loading of only 0.10 mg(Pt-Ru) cm(-2) capable of ach

294 tional durability under a demanding ultralow PGM loading (0.070 mg(PGM) cm(-2)) due to the non-contac

295 making it possible to detect 40 pM DNA using PGM that can detect glucose only at the mM level.

296 interference (RNAi) suggests that, in vivo, PGM activity is catalysed by both enzymes.

297 Grand stability challenges exist when PGM catalyst loading is decreased in a membrane electrod

298 r generation unit of a PEM fuel cell-or when PGM-free catalysts are integrated into an MEA.

299 i presence was significantly associated with PGM presence (odds ratio 832.9, P < 0.001) and SDD prese

300 ult, these catalysts-whether with or without PGMs, such as Rh and Pt-show improved activity for sever

301 ers (P < or =.05) by 31% (AGM) and 32% (WM) (PGM, not significant).