ライフサイエンスコーパス: PLT

1 PLT and ALC were compared between patients with and with

2 PLT and WBC counts were both inversely related to MD adh

3 PLT conducted every 3 days would not only eliminate infe

4 PLT proteins and CUC2 regulate the transcription of the

5 PLT proteins bind to and activate the CUC2 promoter.

6 PLT was greater than 150,000 in 15% of patients at the d

7 PLT-R, with 25-week follow-up (IQR, 14-68) occurred in 4

8 PLT-to-S. aureus exposure ratios of > or = 10:1 yielded

9 PLT/uPA-T recognizes human alphaIIbbeta3 on both quiesce

10 PLTs exist in many well-researched systems where the PLT

11 PLTs represents 18% of all disulfide containing proteins

12 PLTs were obtained every 3 months, and HVPG measurements

13 In total, 199 PLT recipients were enrolled including 112 (56.3%) short

14 Sixteen SOC (53.3%) received FFP, 10 (33.3%) PLT, and 4 (13.3%) both FFP and PLT.

15 20 known MPV associations, we identified 32 PLT and 18 MPV associations not previously observed in t

16 e NLR 5.3 (aHR: 0.68), MLR 0.73 (aHR: 0.43), PLT > 145 (aHR: 0.48) and PLR 534 (aHR: 0.48) were assoc

17 1 < 50 pg/mL, n = 9; IL-6 < 10 pg/mL, n = 5 [PLT 203,000 +/- 7,500/microL].

18 we present our experience of performing 700 PLT over a period of 13 y.

19 hor and T540 HGB (r2 = .95), HCT (r2 = .95), PLT (r2 = .94), and WBC (r2 = .95) results (n = 408); si

20 S. aureus response mechanism involving (i) a PLT-to-S. aureus ratio sufficient for activation; (ii) t

21 Cucumber basic protein (CBP) is a PLT which has a relatively short Cu(II)-S(Met89) axial b

22 different, and what they can teach us about PLT formation.

23 tion of P2X(1)/P2Y(12) receptors on adjacent PLTs; and (iv) the recursive amplification of PMP and PK

24 mbers of the AINTEGUMENTA-LIKE/PLETHORA (AIL/PLT) and WUSCHEL-related homeobox (WOX) gene families, a

25 mbers of the AINTEGUMENTA-LIKE/PLETHORA (AIL/PLT) transcription factor family, including AINTEGUMENTA

26 Arabidopsis AINTEGUMENTA-LIKE/PLETHORA (AIL/PLT) transcription factor family.

27 Arabidopsis thaliana that encode related AIL/PLT transcription factors: AINTEGUMENTA (ANT), AINTEGUME

28 Therefore, all PLT genes can activate the formative cell divisions that

29 is demonstrated that sex and AST/PLT and ALT/PLT counts were not associated with OS (p > 0.05 for all

30 16 +/- 0.001 log fL; P < 1.08 x 10(-24)) and PLT (per-G effect -4.55 +/- 0.80 10(9)/L; P < 7.19 x 10(

31 5), HCT (-0.21+/-1.5), WBC (0.79+/-1.3), and PLT values (-9.2+/-16.6) as well as STKS HGB (-0.08+/-0.

32 s levels of TPO and IL-11, but not IL-6, and PLT counts in the MAT/BMT patients (TPO: r = -0.57, P <

33 ), HCT (-0.69+/-2.3), WBC (-0.62+/-5.8), and PLT values (-10.2+/-21.4).

34 ter STKS HGB (r2 = .92), HCT (r2 = .91), and PLT (r2 = .94) results (n = 141).

35 6.7%; P = 0.009 vs. SOC), and 3 both FFP and PLT (not significant).

36 , 10 (33.3%) PLT, and 4 (13.3%) both FFP and PLT.

37 s identified here between miR396 and GRF and PLT transcription factors are necessary to establish the

38 icant correlation was found between HVPG and PLT at the baseline, year 1, and year 5 (P < 0.0001).

39 ared with SOC (transfusion guided by INR and PLT count), without an increase in failure to control bl

40 ion glaucoma eyes demonstrate reduced LC and PLT thickness compared with POAG, PACG, and healthy eyes

41 CT were associated significantly with LC and PLT thickness.

42 d survival between groups LR and LLT, LR and PLT, and PLT and SLT.

43 entify causal protein biomarkers for MPV and PLT among 71 CVD-related plasma proteins measured in FHS

44 indicating that MDF acts upstream of PIN and PLT gene expression.

45 l between groups LR and LLT, LR and PLT, and PLT and SLT.

46 According to the models, RDW and PLT were the most significant hematological factors for

47 ormalized by platelet count (VITRO score and PLT ratio) are promising biomarkers to predict the risk

48 oligodeoxynucleotide (ODN) sequestration and PLT clumping upon addition of bacterial/viral ODNs.

49 ists of increasingly narrow specificity, and PLT adhesion receptors (CD41, CD42b, and CD62P).

50 stigate the relationship between varices and PLT at the time of endoscopy, (2) investigate whether ch

51 WBC and PLT counts were the most actionable routine tests for ex

52 ness of the peripheral microtubule coil, and PLTs are capable of enlarging in culture to generate bar

53 lization of 125I-rmTPO by megakaryocytes and PLTs in the spleens and marrows of ITP mice was also dem

54 expansion of stem/progenitors and of MKs and PLTs via dysregulated TPO turnover.

55 > 85% efficiency and 10-15% loss of RBCs and PLTs while processing whole blood diluted with saline to

56 ormance, with minimal activation of WBCs and PLTs and no measurable damage to RBCs.

57 irradiation (irradiated) or rabbit antimouse PLT serum (RAMPS) for 1 day (1 d RAMPS) and 5 days (5 d

58 Reintroduction of any PLT clade member in the mutant primordia completely rest

59 A receiver operating curve did not show any PLT with high sensitivity or specificity for the presenc

60 nules, vacuoles and dense tubular system) as PLTs from peripheral blood determined by electron micros

61 ssion analysis demonstrated that sex and AST/PLT and ALT/PLT counts were not associated with OS (p >

62 n, we found that the PTT treatment augmented PLT-AuNRs targeting to the tumor sites and in turn, impr

63 oth auxin/PLETHORA (PLT)-dependent and auxin/PLT-independent redox signaling pathways.

64 In these patients, baseline PLT >/= 100,000/muL and lack of rapid early platelet dec

65 Because PLT number and size are inversely proportional, this rai

66 r PLT count, whereas the association between PLT count and the MD was not affected by adjustment for

67 included incidence and severity of bleeding, PLT transfusions, quality of life, leukemia-free surviva

68 o date of loss of PLT-R, defined as bleeding/PLT count <30 x 10(3)/mm(3) or last date in observation)

69 ting the association between the MD and both PLT and WBC counts.

70 on platinum-based combination chemotherapy (PLT) and checkpoint inhibitors (CPIs) have limited optio

71 negative feedback loop based on circulating PLT counts, but also may, in part, be regulated by a var

72 gest that the absolute number of circulating PLTs may not always be the sole regulator of endogenous

73 go repeated abscissions to yield circulating PLTs.

74 intention-to-treat (ITT) analysis comparing PLT and SLT strategies.

75 deletion in PLTs and MKs did not compromise PLT formation but caused thrombocytosis, and resulted in

76 ker CD62P; c) platelet-leukocyte conjugates (PLT/LEU) and leukocyte activation marker CD11b; and d) i

77 Conversely, PLT activates MIR396 in the stem cells to repress the GR

78 A combination of platelet impedance count (PLT-I) and NEUT-Y at day 3 post-injury exhibited good di

79 e thrombocytopenic duration (platelet count (PLT) < 20,000 per microliter)to o.25, 0, 0.5 d, respecti

80 tine hemostasis tests except platelet count (PLT) and in all TEG parameters, on the first day of infe

81 fically with measurements of platelet count (PLT) and mean platelet volume (MPV).

82 an corpuscular volume (MCV), platelet count (PLT) and white blood cell (WBC) count.

83 an platelet volume (MPV) and platelet count (PLT) are highly heritable and tightly regulated traits.

84 an platelet volume (MPV) and platelet count (PLT) are platelet measures that have been linked to card

85 The mean value of platelet count (PLT) before procedure increased from 22.0 +/- 15.0 to 87

86 reement regarding a specific platelet count (PLT) that can reliably predict GEV.

87 ssion analysis revealed that platelet count (PLT), age, AST, and INR were significantly associated wi

88 Hemoglobin (HGB), platelet count (PLT), red blood cell count, and white blood cell count (

89 1% < MAF < 5%) variants with platelet count (PLT), red blood cell indices (MCH and MCV) and HDL chole

90 tive thrombocytopenia (nadir platelet count [PLT] < 20,000/mm3), as well as the whole group of patien

91 rombocytopenia purpura (ITP), with decreased PLT survival, but intact bone marrow megakaryocytopoiesi

92 ents, silencing GP-5, GRN, and MPO decreased PLTs.

93 d internalization/turnover by Jak2-deficient PLTs.

94 ms that regulate PLT formation and determine PLT size offers the promise of improved therapies for cl

95 000 per microliter), and elicited an earlier PLT recovery.

96 out twice as fast, and lost ~ 2-3-fold fewer PLTs, while operating at a flow rate compatible with the

97 ficantly lower use of blood components (FFP, PLTs, and cryoprecipitate) in the TEG group compared wit

98 blood components (fresh frozen plasma [FFP], PLTs, and cryoprecipitate) versus 87.2% in the SOC group

99 putatively causal proteins for MPV and 4 for PLT.

100 nd MDS disappeared when further adjusted for PLT count, whereas the association between PLT count and

101 The differentiation medium was collected for PLT production analysis by flow cytometry, transmission

102 on to infer causal relations of proteins for PLT/MPV.

103 erminal megakaryopoiesis is not required for PLT production, and that Jak2 loss in PLTs and MKs resul

104 nalysis of Exomechip association results for PLT and MPV in 157,293 and 57,617 individuals, respectiv

105 on and cancer targeting characteristics from PLTs and good photothermal property from AuNRs.

106 nd that the generated MKs release functional PLTs.

107 , control vs. differentiation); 3) Generated PLTs were functional as evidenced by the up-regulation o

108 r patients, ITT survival was better in group PLT compared with group LR.

109 ase-free survival (DFS) were better in group PLT versus group LR (OS 73%/63% vs. 58%/35%, P = 0.0007;

110 out (7.1%), 340 finally underwent PLT (group PLT).

111 e and long-term outcomes compared with group PLT (starting from time of LT) (OS 54%/54% vs. 73%/63%,

112 t, to its uptake and degradation by the high PLT turnover and increased mass of megakaryocytes.

113 ad both reduced odds of being in the highest PLT-count group (MDS: odds ratio = 0.50; 95% confidence

114 of TLR9 organization and signaling in human PLTs.

115 omoting antibacterial activity makes Van-ICG@PLT a valuable addition to the existing arsenal of thera

116 ar-infrared (NIR) laser irradiation, Van-ICG@PLT exhibits significant cytotoxicity against 4T1 cells.

117 post-surgery recurrence mice model, Van-ICG@PLT is shown to efficiently ablate tumors in tumor-beari

118 Our findings demonstrate that Van-ICG@PLT preferentially accumulates at surgical wound.

119 Taken together, Van-ICG@PLT represents a promising paradigm in post-surgical adj

120 In this study, a nano-sensor system, Van-ICG@PLT, is constructed by a membrane camouflage and small m

121 surface adhesion receptors failed to impede PLT anti-S. aureus responses.

122 VPG correlates somewhat with PLT, changes in PLT cannot be used as a surrogate for HVPG changes.

123 GEV, and (3) investigate whether changes in PLT correlate with the hepatic venous pressure gradient

124 ndoscopy, (2) investigate whether changes in PLT from the baseline over time can predict the developm

125 iviral prophylaxis to prevent CMV disease in PLT, through a prospective cohort study of primary PLT (

126 vors and nonsurvivors on day 1 were found in PLT/LEU (p = .001), CD11b (p = 0.02), and EMP/MONO (p =

127 signal-related kinase (ERK), is involved in PLT activation.

128 s TLR9 to a new intracellular compartment in PLTs and (b) describes a novel mechanism of TLR9 organiz

129 Pf4-Cre-mediated Jak2 deletion in PLTs and MKs did not compromise PLT formation but caused

130 VAMP 8, which regulates its distribution in PLTs on contact activation (spreading).

131 r treatment is not due to JAK2 inhibition in PLTs and MKs, but rather due to JAK2 inhibition in stem/

132 ed for PLT production, and that Jak2 loss in PLTs and MKs results in non-autonomous expansion of stem

133 dary to both marrow hypoplasia and increased PLT destruction.

134 e, nor the inhibition of anti-HPA-1a-induced PLT phagocytosis, were affected by N-glycan modification

135 it would become endemic with 4-day interval PLT, and without testing, it would result in an epidemic

136 Gold nanorods (AuNRs) were first loaded into PLTs by electroporation and the resulting AuNR-loaded PL

137 Isolated PLTs were incubated with ISP479C or ISP479R (PLT/S. aure

138 PLTs were incubated with ISP479C or ISP479R (PLT/S. aureus ratio range, 1:1 to 10,000:1) in the prese

139 In addition to confirming 47 known PLT and 20 known MPV associations, we identified 32 PLT

140 4) was developed: age ([yr] x AST [U/L]) / ((PLT [10(9)/L]) x (ALT [U/L])(1/2)).

141 Labeled PLTs were also found within splenic macrophages.

142 nd may be related to "young PLTs" and "large PLTs" of both inherited and acquired macrothrombocytopen

143 crothrombocytopenias to establish how "large PLTs" observed in both conditions are similar, how they

144 , and EDI OCT, as well as measurement of LC, PLT thickness, and LC depth.

145 lectroporation and the resulting AuNR-loaded PLTs (PLT-AuNRs) inherited long blood circulation and ca

146 ntially life saving for individuals with low PLT numbers; however, previous work revealed that PLT tr

147 may have outcomes comparable to primary LT (PLT).

148 A rise in the mean PLT after the 2nd postoperative week reflects proper gra

149 nsplant period (first 2 weeks), but the mean PLT exceeded preoperative levels during the 3rd and 4th

150 Additionally, the mean PLT volumes of RAMPS mice were significantly higher than

151 ent strategy to prevent anti-HPA-1a-mediated PLT destruction in FNAIT.

152 Strikingly, we find that Atg2-mediated PLT is non-rate limiting for autophagosome biogenesis be

153 g a multifrequency linear array 7.2-18.0-MHz PLT-1204BX transducer focused at the level of the flexor

154 s was the bound 125I-rmTPO (cpm) per million PLT (P <.05).

155 tential new stem cell source for in vitro MK/PLT production.

156 levels remained undetectable (< 150 pg/mL, [PLT 30,500 +/- 5,500/microL], n = 15).

157 P < .05, n = 19; IL-6: 25.8 +/- 8.4 pg/mL, [PLT 32,800 +/- 5,057/microL], P > .05, n = 4] v normal d

158 < .001, n = 12; IL-11: 227.9 +/- 35 pg/mL, [PLT 32,900 +/- 57,000/microL], P < .05, n = 19; IL-6: 25

159 apy (BMT/MAT) (TPO: 1,455.5 +/- 87.3 pg/mL, [PLT 39,600 +/- 7,800/microL], P < .001, n = 12; IL-11: 2

160 nificantly increased (328.0 +/- 92.6 pg/mL, [PLT: 20,900 +/- 3,000/microL], P < .05, n = 25).

161 -HPA-1a antibodies in vivo in a mouse model (PLT clearance after 5 hours; 18% vs 62%, in the presence

162 Importantly, in two murine injury models, PLT/uPA-T did not lyse preexisting clots, even when admi

163 These results suggest a multifactorial PLT anti-S. aureus response mechanism involving (i) a PL

164 Both the nadir PLT and the percentage of the platelet fall were indepen

165 Despite several obstacles, PLT has seen impressive growth in the recent years.

166 l, we demonstrate that the administration of PLT-AuNRs and localizing laser irradiation could effecti

167 he unique self-reinforcing characteristic of PLT-PTT in cancer therapy.

168 A combination of PLT-I and NEUT-Y show potential for the early diagnosis

169 improved therapies for clinical disorders of PLT production and an important source of PLTs for infus

170 Primary end points were duration of PLT response (PLT-R; calculated from the time of PLT-R t

171 nst a backdrop of this changing landscape of PLT in India, we present our experience of performing 70

172 ed from the time of PLT-R to date of loss of PLT-R, defined as bleeding/PLT count <30 x 10(3)/mm(3) o

173 The outcomes of PLT performed over the first 7 y were compared with thos

174 :1) in the presence or absence of a panel of PLT inhibitors, including P2X and P2Y receptor antagonis

175 Pretreatment of PLT-Ecto with anti-TGF-beta1 neutralizing Ab restored su

176 endent manner, suggesting that recipients of PLT transfusions may experience reduced NK cell function

177 sent a failure in the intermediate stages of PLT production?

178 response (PLT-R; calculated from the time of PLT-R to date of loss of PLT-R, defined as bleeding/PLT

179 t-PA resistance in AIS through activation of PLTs and ECs.

180 oss-sectional or longitudinal evaluations of PLTs are inadequate noninvasive markers for GEV.

181 (Oct4 and Sox2) expression; 2) The level of PLTs in the differentiation medium was 16 +/- 1 number/m

182 Preincubation of PLTs with type IV collagen specifically increased TLR9 a

183 of PLT production and an important source of PLTs for infusion.

184 Identifying genetic effects on PLT and MPV can provide mechanistic insights into platel

185 y, the phagophore-ER tether Atg2 is the only PLT protein known to drive phagophore expansion in vivo.

186 hy (defined in this study as INR >1.8 and/or PLT count < 50 x 10(9) /L) and nonvariceal upper GI blee

187 if the reaction time (r) was >40 min and/or PLT if maximum amplitude (MA) was <30 mm.

188 All SOC patients received FFP and/or PLT per hospital guidelines.

189 eleasing PLT microbicidal proteins (PMPs) or PLT kinocidins (PKs).

190 jection criteria of WBC >=11 000 cells/uL or PLT >=300 000 cells/uL would have led to PCR refusal in

191 the MDF-dependent pathway in regulating PIN/PLT- and WUS/CLV-mediated meristem activity.

192 t3p, fungal laccases and some plantacyanins (PLTs).

193 (GA), but not the soleus (SOL) or plantaris (PLT) muscles, of D14 mice.

194 Platelet (PLT) and white blood cell (WBC) counts are 2 markers of

195 Platelet (PLT) production represents the final stage of megakaryoc

196 Platelet (PLT) transfusions are potentially life saving for indivi

197 ased on white blood cell (WBC) and platelet (PLT) counts, were developed and prospectively applied in

198 n blood, red blood cell (RBC)- and platelet (PLT)-derived EVs and studied their interactions with pro

199 ic cytokine levels and circulating platelet (PLT) counts, we measured the levels of thrombo-poietin (

200 oietin (TPO) levels and peripheral platelet (PLT) counts in patients with thrombocytopenia secondary

201 1-risk MDS, patients with a stable platelet (PLT) count (<30 x 10(3)/mm(3)) received eltrombopag or p

202 We previously showed that platelet (PLT) alpha granule-delivered urokinase plasminogen activ

203 spartate aminotransferase (AST) to platelet (PLT) ratio index (APRI), the albumin-bilirubin (ALBI) sc

204 ational normalized ratio [INR] and platelet [PLT] count), and its use may avoid unnecessary blood com

205 rophils (ANC to < 500/microL) and platelets (PLT < 20,000/microL) were significantly enhanced in the

206 s), white blood cells (WBCs), and platelets (PLT).

207 r harnesses the innate tropism of platelets (PLT) to deliver vancomycin (Van) and indocyanine green (

208 fresh frozen plasma (FFP) and/or platelets (PLT).

209 Platelets (PLTs) act in antimicrobial host defense by releasing PLT

210 In addition, NETs activated platelets (PLTs) and endothelial cells (ECs), stimulating a procoag

211 ) from red blood cells (RBCs) and platelets (PLTs), is a life-saving procedure used for treating pati

212 n (HPA)-1a, which opsonizes fetal platelets (PLTs).

213 bsequent production of functional platelets (PLTs).

214 ed the impact of Jak2 deletion in platelets (PLTs) and megakaryocytes (MKs) on blood counts, stem/pro

215 Human and murine platelets (PLTs) variably express toll-like receptors (TLRs), which

216 /L, hemoglobin [Hgb] > 12.0 g/dL, platelets [PLT] > 100 x 10(9)/L), as well as resolution of splenome

217 RAM maintenance through both auxin/PLETHORA (PLT)-dependent and auxin/PLT-independent redox signaling

218 eedling roots also exhibit reduced PLETHORA (PLT), SCARECROW and SHORTROOT gene expression, a loss of

219 The GRFs repress PLETHORA (PLT) genes, regulating their spatial expression gradient

220 We show that PLETHORA (PLT) and AINTEGUMENTA (ANT) genes, which encode stem cel

221 Recent work has identified the PLETHORA (PLT) genes as master regulators of basal/root fate, wher

222 Here, we show that three PLETHORA (PLT) genes, PLT3, PLT5, and PLT7, regulate de novo shoot

223 characterize the effects of three PLETHORA (PLT) transcription factors, PLT3, PLT5, and PLT7, during

224 poration and the resulting AuNR-loaded PLTs (PLT-AuNRs) inherited long blood circulation and cancer t

225 Four of these factors, preoperative PLT, intra-operative platelet transfusions, re-transplan

226 For preoperative PLT, platelet transfusions during the operation, re-tran

227 t period is correlated with low preoperative PLT, massive platelet transfusions, and re-transplantati

228 The preoperative PLT, intra-operative platelet transfusion requirements,

229 NGM-SZ21 prevented PLT destruction induced by maternal anti-HPA-1a antibodi

230 hrough a prospective cohort study of primary PLT (aged <18 years) recipients enrolled in the Society

231 ctable or mUC who had progressed after prior PLT and CPI.

232 reated mUC that has progressed on both prior PLT regimens and CPI.

233 ript is specifically up-regulated during pro-PLT production and is distributed to a novel electron-de

234 We also tested protein-PLT/MPV association in FHS participants.

235 d FFP alone (P < 0.0001 vs. SOC), 2 received PLT (6.7%; P = 0.009 vs. SOC), and 3 both FFP and PLT (n

236 Recently, PLT-Ecto were shown to reduce proinflammatory cytokine r

237 of the cytoskeletal mechanisms that regulate PLT formation and determine PLT size offers the promise

238 following thrombin stimulation; 4) Released PLTs showed similar ultra-structure characteristics (alp

239 t in antimicrobial host defense by releasing PLT microbicidal proteins (PMPs) or PLT kinocidins (PKs)

240 induced in the mutant primordia, rendering "PLT-null" LRP.

241 ry end points were duration of PLT response (PLT-R; calculated from the time of PLT-R to date of loss

242 Additional analysis revealed PLT, age, AST, and ALT as an alternative model.

243 rbell-proPLTs that divide to yield 2 smaller PLT products.

244 chromatography indicated that staphylocidal PLT releasates contained PMPs and PKs.

245 During storage, PLT intended for transfusion continuously shed ectosomes

246 ed to ST gene expansions of two subfamilies, PLT and STP, in S. spontaneum, indicating an early evolu

247 Subsequent PLT destruction is mediated via the Fc part of the alloa

248 ualize our current understanding of terminal PLT production against the backdrop of human macrothromb

249 by 3-day interval population-level testing (PLT), while it would become endemic with 4-day interval

250 etween the studied EVs and demonstrated that PLT-derived EVs were more efficiently internalized by PC

251 rs predict mortality on day 1, we found that PLT/LEU had the best predictive value among the markers

252 umbers; however, previous work revealed that PLT transfusions are associated with increased infection

253 In sum, our study showed that PLT-Ecto could inhibit NK cell effector function in a TG

254 The PLT-CUC2 module is required for vascular regeneration, b

255 At ratios below 10:1, the PLT antistaphylococcal efficacy relative to the intrinsi

256 e biogenesis because membrane tether and the PLT protein Vps13 localizes to the rim and promotes the

257 how an antagonistic relationship between the PLT and HD-ZIP III genes in specifying the root and shoo

258 d with training, and remained blunted in the PLT and SOL even after 28 days of detraining, at a time

259 The nadir of the drop in the PLT most commonly occurred on posttransplant day 4.

260 ups, with increases at D1, D7 and D14 in the PLT, SOL and GA muscles, respectively.

261 Among the 22 lower limbs, the PLT was present in 16 (72.7%) and absent in six (27.3%).

262 eltrombopag patients, 12/47 (25.5%) lost the PLT-R, with cumulative thrombocytopenia relapse-free sur

263 a specific P2Y(12) antagonist) mitigated the PLT staphylocidal response against both strains, correla

264 0.5 d, respectively, and the severity of the PLT nadir (28,000, 43,000, and 30,000 per microliter, re

265 tions of this specific topology in which the PLT-forming disulfide may act as a molecular switch for

266 The PLTs were compared between subjects who did and did not

267 st in many well-researched systems where the PLTs have previously been unnoticed.

268 elet-facilitated photothermal tumor therapy (PLT-PTT) strategy, in which PLTs act as carriers for tar

269 plification of PMP and PK release from these PLTs.

270 In the absence of this PLT-mediated regeneration response, leaf ground tissue c

271 Thus, PLT/uPA-T represents the prototype of a platelet-targete

272 3) mum; p = 0.04) and the prelaminar tissue (PLT) was significantly thicker (269 (162/360) mum vs. 13

273 cells and full PBMCs from healthy donors to PLT-Ecto.

274 re, and the gamma-glutamyl transpeptidase to PLT ratio (GPR) with respect to OS in treatment-naive mC

275 ified 4 proteins that are causally linked to PLTs.

276 Recently, the Pierced Lasso Topology (PLT) was discovered in which a covalent bond forms an in

277 ficient non-vesicular phospholipid transfer (PLT) across phagophore-ER contacts (PERCS).

278 ceptance of pediatric liver transplantation (PLT) in this part of the world has been slow because of

279 ation after pediatric liver transplantation (PLT), the optimal method for CMV prevention is uncertain

280 26 dropped-out (7.1%), 340 finally underwent PLT (group PLT).

281 All 700 children (<18 y old) who underwent PLT from January 2011 to February 2024 were included in

282 n-activatable, low-molecular-weight pro-uPA (PLT/uPA-T).

283 Co-regulation of WBC-PLT dynamics is a fundamental mechanism of acute inflamm

284 ese effects could antagonized, in part, when PLT-Ecto were preincubated with anti-TGF-beta1 Ab.

285 Whether PLT-Ecto modify NK cells remains unclear.

286 l tumor therapy (PLT-PTT) strategy, in which PLTs act as carriers for targeted delivery of phototherm

287 portal hypertension (HVPG < 10 mm Hg) whose PLT remained greater than 100,000 had a 2-fold reduction

288 Patients with mild portal hypertension whose PLT remains greater than 100,000 have significantly less

289 roteins were associated with MPV and 31 with PLT.

290 to identify genetic variants associated with PLT and MPV.

291 cell adhesion molecule) were associated with PLT, while MPO (myeloperoxidase) showed significant asso

292 Several variants associated with PLT/MPV (PEAR1, MRVI1, PTGES3) were also associated with

293 analyses of genetic variants associated with PLT/MPV with protein quantitative trait locus variants a

294 and long-term outcomes were comparable with PLT.

295 Only AFI and ALT interacted inversely with PLT and positively with MPV in men.

296 ociation of variants at the COPZ1 locus with PLT as well as replication of four previously reported l

297 CHC, and a variant at the ARHGEF3 locus with PLT, as well as replication of four previously reported

298 Although HVPG correlates somewhat with PLT, changes in PLT cannot be used as a surrogate for HV

299 inverse correlation of circulating TPO with PLT counts during steady-state immune thrombocytopenic m

300 partially accounted for the association with PLTs.

301 barbell-proPLTs and may be related to "young PLTs" and "large PLTs" of both inherited and acquired ma