ライフサイエンスコーパス: PMI

1 PMI 5011 also attenuated the FFA-induced upregulation of

2 PMI 5011 attenuates the reduction in insulin signaling i

3 PMI 5011 had no effect on ceramide formation or accumula

4 (PMI 5011) improves insulin action, yet the precise mecha

5 PMI compares observed trade with a benchmark of what is

6 PMI competes with p53 for MDM2 and MDMX binding at an af

7 PMI is a common complication after noncardiac surgery an

8 PMI is an inhibitor of the protein-protein interaction (

9 PMI is associated with increased in-hospital mortality i

10 PMI may have significantly contributed to reducing the b

11 PMI may normally be used to catabolize excess mannose ra

12 PMI occurred after 397 of 2546 surgeries (16%; 95% confi

13 PMI program implementation was associated with a signifi

14 PMI rates according to the SCAI or EXCEL definition were

15 PMI rates according to the SYNTAX and Fourth Universal D

16 PMI values also indicate the capacity to trade more (the

17 PMI was classified as a myocardial infarction occurring

18 PMI was defined as an absolute high-sensitivity cardiac

19 PMI was defined as creatine kinase-MB isoenzyme level >

20 PMI was defined as initiation of VT during pace-mapping

21 PMI(Prot) occurred in 34 of 935 (3.6%) patients after PC

22 PMI(Prot) was associated with a consistent hazard of car

23 PMIs according to the SYNTAX and Fourth Universal Defini

24 PMIs after PCI were associated with 10-year mortality re

25 n was stratified into those experiencing (1) PMI with type 4a MI, (2) PMI without type 4a MI, or (3)

26 tion coverage of malaria interventions in 19 PMI-recipient and 13 non-recipient countries between 199

27 se experiencing (1) PMI with type 4a MI, (2) PMI without type 4a MI, or (3) no PMI.

28 Universal Definition of MI (types 4a and 5) (PMI(UD)) required lesser biomarker elevations but with s

29 ree enthalpies DeltaG(298)(Z vs. E) are 2.6 (PMI), 2.3 (PYI), and 6.0 (PUI) kcal/mol and for the free

30 tivation DeltaG(298)(Z --> E) they are 21.6 (PMI), 21.1 (PYI) and 19.7 (PUI) kcal/mol.

31 A PMI-derived metabolic signature consisting of aconitic a

32 he active site of PaPGI/PMI argues against a PMI mechanism involving a trans-enediol intermediate.

33 -based STI/HIV intervention (HORIZONS) and a PMI consisting of brief telephone contacts every 8 weeks

34 The non-risk-adjusted PMI was 0.115 (SD = 0.023) for all centers and 0.113 (SD

35 percentage points (95% CI 0.79-12.47) after PMI implementation.

36 y changed in the peripheral vein blood after PMI in a derivation cohort (n=15; P<5.70E-5).

37 proteins that increased within 1 hour after PMI, 23 were also elevated in patients with spontaneous

38 rization laboratory at our institution after PMI from 2003 to 2012, who had noncardiac surgery within

39 tained before and at various intervals after PMI, with patients undergoing elective diagnostic corona

40 s were detected as early as 10 minutes after PMI in an initial derivation group and were validated in

41 tained before and at 10 and 60 minutes after PMI, and protein changes were assessed by repeated-measu

42 e discussion of the halogen-bonded aggregate PMI x ClCH(3) exemplifies that the asymmetry in N-invers

43 e the identical electronic properties of all PMI amphiphiles.

44 repeatable in a mouse model system, allowing PMI to be estimated within approximately 3 days over 48

45 A factorial analysis of gender, age, and PMI with respect to copy number also showed no statistic

46 AmCYAN1 and PMI protein accumulation levels were maintained.

47 showed no evidence of decreasing AmCYAN1 and PMI protein levels across generations and no transgene s

48 ication to 1.00 for postoperative death, and PMI was derived.

49 on Brain Bank, with data on age, gender, and PMI) were analyzed for HSV-1 DNA copies (HSV-1 DNA polym

50 mics with epidemiological, intervention, and PMI-financing data to estimate the contribution PMI has

51 h a panel of p53-derived peptide ligands and PMI, a p53-mimicking but more potent peptide antagonist

52 e-mapping, electrograms that exhibit MES and PMI may be specific for sites critical to reentry.

53 ieved by coupled assays in which the PMM and PMI primary products are in vitro subjected to another e

54 Both PMI(Prot) and PMI(UD) were associated with 5-year cardiovascular morta

55 ifferent kinds of reactions, whereas TIM and PMI have different structures but catalyze similar react

56 have improved freedom from recurrent VT, and PMI of VT predicts successful sites of termination durin

57 Molecular ions corresponding to apo-PMI monomer were obtained by dialyzing the holoenzyme ag

58 ovel chemical tool (hereafter referred to as PMI), which drives mitochondria into autophagy without c

59 the vast majority of PMIs are asymptomatic, PMI usually is missed in the absence of systematic scree

60 isability Adjusted Life Year (DALY) averted, PMI-funded interventions are highly cost-effective.

61 Bacteriochlorin analogue BC-PMI has more extended spectral coverage (350-750 nm) and

62 containing eight perylenes in benzonitrile, PMI decays approximately 80% by energy transfer (forming

63 the first to assess the association between PMI and all-cause child mortality in SSA with the use of

64 The association between PMI and mortality was analyzed by Cox regression.

65 cused on the electronic interactions between PMI chromophores.

66 Both PMI(Prot) and PMI(UD) were associated with 5-year cardio

67 The performance of both PMI and PDI derivatives in organic devices may be limite

68 Here, five covalently bound PMI dimers with varying degrees of electronic interactio

69 ed intramolecular H-bonding network in bound PMI that contributed to its conformational stability, th

70 Each dollar of per-capita PMI expenditures in a country, a measure of PMI intensit

71 Per-capita PMI spending was also associated with a modest increase

72 embrane-traversing delivery vehicle to carry PMI for anticancer therapy.

73 let yield (<5%) is observed for the cofacial PMI dimers.

74 ene driven by a CMP promoter and the E. coli PMI gene driven by either a CMP or Ubi promoter, were us

75 ved HORIZONS and a time- and dose-consistent PMI focused on general health.

76 -financing data to estimate the contribution PMI has made to malaria control via funding for long-las

77 .7%) differed from that in healthy controls (PMI=9.2+/-3.8%; P<0.01) but not from that in umbilical c

78 Conversely, PMI(UD) was strongly associated with cardiovascular mort

79 ant to proteolysis, both (D)PMI-alpha and (D)PMI-gamma failed to actively traverse the cell membrane

80 pite being resistant to proteolysis, both (D)PMI-alpha and (D)PMI-gamma failed to actively traverse t

81 in-targeting cyclic-RGD peptide, however, (D)PMI-alpha exerted potent p53-dependent growth inhibitory

82 The prototypic d-peptide inhibitor (D)PMI-alpha binds ((25-109))MDM2 at an affinity of 220 nM

83 for ((25-109))MDM2 has been improved over (D)PMI-alpha by 3 orders of magnitude (K(d) = 220 pM).

84 ibitor of the p53-MDM2 interaction termed (D)PMI-alpha (TNWYANLEKLLR) that competes with p53 for MDM2

85 mal d-peptide antagonists of MDM2, termed (D)PMI-alpha, beta, gamma.

86 tive d-peptide antagonist of MDM2, termed (D)PMI-delta, of which the binding affinity for ((25-109))M

87 in a distinct D-peptide inhibitor termed (D)PMI-gamma (DWWPLAFEALLR) that binds MDM2 at an affinity

88 X-ray crystallographic studies validate (D)PMI-delta as an exceedingly potent inhibitor of the p53-

89 Thirteen patients (30%) demonstrated PMI, and termination of VT was seen in 95% (18/19) of si

90 atients with CKD before undergoing dialysis (PMI=36.1+/-11.7%) differed from that in healthy controls

91 Robust perylene-3,4-dicarboximide (PMI) pi-aggregates provide important light-harvesting an

92 rophobic residues Phe, Trp, and Leu dominate PMI or (17-28)p53 binding to MDM2 and MDMX.

93 ne, the photoexcited perylene-monoimide dye (PMI) decays rapidly ( approximately 3.5 ps) and predomin

94 n path of the isomerization (Z)-PMI <==> (E)-PMI revealed a remarkable stabilization due to asymmetry

95 The multivariable relationship between each PMI type and 5-year mortality was determined.

96 es may provide a novel method for estimating PMI that avoids many of these limitations.

97 eveloped into a forensic tool for estimating PMI.

98 iscovery rate; 52 patients (12%) experienced PMI.

99 In addition, the tarragon extract PMI-5011 activated Klf4 and orexigenic neuropeptides and

100 ngs compared to the wild type (WT) following PMI.

101 To elucidate the molecular determinants for PMI activity and specificity, we performed a systematic

102 tor haplotype improved prediction models for PMI based on traditional risk factors alone (C-statistic

103 polymorphisms improved prediction models for PMI based on traditional risk factors alone (C-statistic

104 SOSP) - E(ITS) is less than 0.5 kcal/mol for PMI and PUI, but it is as high as DeltaE(def) approximat

105 re may be a safe and effective treatment for PMI and improving quality of sleep in patients with meno

106 ately 20% by electron transfer (also forming PMI- Zn+) and approximately 80% by the normal routes ope

107 approximately 20% by hole transfer (forming PMI- Zn+); Zn subsequently decays approximately 20% by e

108 ntaneous Ca2+ sparks in fibers isolated from PMI EDL muscles were also significantly altered.

109 In addition, RyR1 from PMI skeletal muscles were PKA-hyperphosphorylated and de

110 edge-functionalized GNRs, revealing that GNR-PMI formed an intriguing rectangular network.

111 mplex ( approximately 96 kDa) at 18 and 30 h PMI, and was SDS sensitive.

112 At 30 h PMI, each of the parasites, IE cytosol and IE ghost cont

113 parum parasite extracts only from 24 to 36 h PMI, and multiple proteins appeared to be required for t

114 exon events to be most prominent ASE in high PMI group followed by retained intron events.

115 icrospores fail to undergo pollen mitosis I (PMI) and arrest at polarized stage with a single central

116 first haploid division at pollen mitosis I (PMI) but fail at distinct stages of the generative cell

117 therapeutic evaluation of RA mice by NIR-II PMI is shown to be consistent with clinical micro-CT and

118 The TCZ-PNPs-assisted NIR-II PMI provides a new strategy for RA theranostics, therape

119 NIR-II PMI results reveal the excellent targeting abilities of

120 NIR-II photoacoustic (PA) molecular imaging (PMI) is emerging as a promising new strategy for effecti

121 tions were studied of pyrimidin-4(3H)-imine (PMI), pyridin-2(1H)-imine (PYI), and 1H-purine-6(9H)-imi

122 ntribute to the reduced exercise capacity in PMI, out of proportion to the degree of cardiac dysfunct

123 ced amplitude and a prolonged time course in PMI.

124 Monocyte and neutrophil levels were lower in PMI than in NMI monkeys.

125 estimated that the under-5 mortality rate in PMI countries was reduced from 28.9 to 24.3 per 1,000 pe

126 ia burden should a proposed 44% reduction in PMI funding occur.

127 If a 44% reduction in PMI funding were to occur, we predict that this loss of

128 and prolonged, and anemia was more severe in PMI than in NMI monkeys.

129 lymphocyte levels were higher in NMI than in PMI monkeys.

130 se proteins were validated in an independent PMI cohort (n=15; P<2.30E-4); >85% were directionally co

131 that according to the Pain Management Index (PMI), 43.4% of patients with cancer were undertreated.

132 The Postoperative Morbidity Index (PMI) is a quantitative measure of the average burden of

133 tiation of VT, termed pace-mapped induction (PMI).

134 a shape-based principal moments of inertia (PMI) analysis.

135 nitions of procedural myocardial infarction (PMI) are in widespread use.

136 s for peri-procedural myocardial infarction (PMI) following percutaneous coronary intervention (PCI)

137 therapeutic, planned myocardial infarction (PMI) for treatment of hypertrophic cardiomyopathy.

138 cardium and in a post-myocardial infarction (PMI) HF model evaluated in wild-type (wt-PMI) and Nod1(-

139 risk of postoperative myocardial infarction (PMI) in patients undergoing coronary artery bypass graft

140 esis of postoperative myocardial infarction (PMI), a multifactorial disorder with significant inter-p

141 PCI) in perioperative myocardial infarction (PMI), even though PMI is a major cause of mortality in p

142 onal model of planned myocardial infarction (PMI), patients undergoing septal ablation for hypertroph

143 uman model of planned myocardial infarction (PMI).

144 ignaling in a rat postmyocardial infarction (PMI) model of myocardial overload.

145 2 in an exclusively polymicrobial infection (PMI) model.

146 .1; P=.03), placental membrane inflammation (PMI; OR, 2.7; P=.02), and deciduitis (OR, 2.3; P=.03) an

147 including the pointwise mutual information (PMI) measure to provide an indication of interdependenci

148 her degree of probable maternal inheritance (PMI) of functional disorders than controls (12% vs. 1%,

149 derived from a high-affinity MDM2 inhibitor PMI.

150 nited States President's Malaria Initiative (PMI) since 2006, no studies have carefully assessed how

151 such as the President's Malaria Initiative (PMI), are vital to maintain progress and pursue further

152 Perioperative myocardial injury (PMI) seems to be a contributor to mortality after noncar

153 Instead, PMI activity may be the result of additional space in th

154 assessment includes Process Mass Intensity (PMI) data from multiple companies to provide preliminary

155 r detecting protein-metabolite interactions (PMIs) to identify lipids that bind to Nur77.

156 stic in predicting the post mortem interval (PMI).

157 urate estimation of the postmortem interval (PMI) is crucial for medico-legal investigations, providi

158 donation source, longer postmortem interval (PMI), and higher body mass index (BMI) were associated w

159 dely used to assess the postmortem interval (PMI), but errors can range from days to months.

160 ect to age, gender, and postmortem interval (PMI).

161 ime of death), and long postmortem interval (PMI).

162 he areas of estimating postmortem intervals (PMIs), locating clandestine graves, and obtaining soil a

163 IE) surface at 30 h post-merozoite invasion (PMI), concomitant with extensive oligomerization.

164 atment of perioperative myocardial ischemia (PMI) because of early graft failure or incomplete revasc

165 cted as the percentage of migrated isoforms (PMI), Epo glycosylation in patients with CKD before unde

166 three key enzymes: phosphomannose isomerase (PMI), phosphomannomutase (PMM) and GDP-mannose pyrophosp

167 f a metalloenzyme, phosphomannose isomerase (PMI), which catalyzes the interconversion of mannose 6-p

168 nomutase (PMM) and phosphomannose isomerase (PMI), which when deficient cause congenital disorders of

169 eductase (AR), and phosphomannose isomerase (PMI).

170 om glucose through phosphomannose isomerase (PMI).

171 that one became the prioritized memory item (PMI) and another the unprioritized memory item (UMI).

172 If funding is maintained, PMI-funded interventions are estimated to avert a furthe

173 The resulting cyclotide MCo-PMI was able to bind with low nanomolar affinity to both

174 tion (mean age, 37.7 +/- 9.4 years; and mean PMI, 5.3 +/- 1.4 hours).

175 d with enhanced inflammation in the KO mice, PMI-induced mortality was also significantly higher in K

176 sed on photosensitizing perylene monomimide (PMI) chromophore amphiphiles were found to show variatio

177 The co-crystal structure of N8A-PMI-(25-109)MDM2 was determined at 1.95 A, affirming tha

178 n association was confirmed between negative PMI score, economic level, and nonspecific setting for c

179 and experimental studies reporting negative PMI scores for adults with cancer and pain published fro

180 4a MI, (2) PMI without type 4a MI, or (3) no PMI.

181 Nod1(-/-)-PMI mice showed significantly fewer ventricular arrhythm

182 Compared with wt-PMI, hearts from Nod1(-/-)-PMI mice had better cardiac function and attenuated stru

183 ne receptors, which was blunted in Nod1(-/-)-PMI cardiomyocytes.

184 Ameliorated cardiac function in Nod1(-/-)-PMI mice was associated with prevention of Ca(2+) dynami

185 er isoproterenol administration in Nod1(-/-)-PMI mice.

186 -type (wt-PMI) and Nod1(-/-) mice (Nod1(-/-)-PMI).

187 se of metabolomics in the discovery of novel PMIs.

188 Np-PMI was substantially more active in vitro than Nutlin-3

189 stematic Ala scanning mutational analysis of PMI and (17-28)p53.

190 The pre-specified protocol definition of PMI (PMI(Prot)) required a large elevation of creatine k

191 0 domain requirements for the degradation of PMI and Sp100 suggests that a common mechanism is involv

192 ll of whom met the criteria for diagnosis of PMI.

193 The effect of PMI 5011 on ceramide accumulation and ceramide-induced i

194 demonstrate that SFN reverses the effects of PMI in co-treated cells by reducing the accumulation of

195 All patients showing evidence of PMI (n=399; 5.3% of total) underwent emergent coronary a

196 validated in a second, independent group of PMI patients.

197 modelling approach to estimate the impact of PMI investments to date in reducing malaria burden and t

198 We have not modelled indirect impacts of PMI funding (such as health systems strengthening) in th

199 The implications of PMI values are demonstrated by using Texas as an example

200 However, the incidence of PMI in whites (n=843) expressing the combined MBL2 5' LY

201 re associated with an increased incidence of PMI.

202 uate the association between introduction of PMI and child mortality rates in sub-Saharan Africa (SSA

203 Introduction of PMI was associated with increased coverage of malaria pr

204 l procedures and allows the investigation of PMI to be extended to 15 days.

205 PMI expenditures in a country, a measure of PMI intensity, was also associated with a reduction in c

206 ults and to develop a model of prediction of PMI.

207 aplotype is a novel independent predictor of PMI and may aid in preoperative risk stratification of w

208 or haplotype was an independent predictor of PMI in whites after primary coronary artery bypass graft

209 s were found to be independent predictors of PMI (adjusted P<0.05; false discovery rate <10%).

210 tor haplotypes are independent predictors of PMI in whites undergoing primary coronary artery bypass

211 Importantly, the C-terminal residue Pro of PMI induced formation of a hydrophobic cleft in MDMX pre

212 The rates of PMI after PCI and CABG vary greatly with different defin

213 The rates of PMI are highly dependent on their definition, which affe

214 The corresponding rates of PMI(UD) were 37 (4.0%) and 20 (2.2%), respectively (diff

215 etermine the rates and clinical relevance of PMI using different definitions in patients with left ma

216 etic contributions of individual residues of PMI and (17-28)p53 to MDM2 and MDMX association.

217 inflammatory pathways contribute to risk of PMI after cardiac surgery.

218 g-term mortality after PCI in the setting of PMI.

219 tion constant for the isomeric substrates of PMI was measured to be 88.8 microM.

220 ensive steric clashes with the C-terminus of PMI or p53 peptide and induces a significant lateral shi

221 mphocyte count 23 times greater than that of PMI monkeys.

222 Because the vast majority of PMIs are asymptomatic, PMI usually is missed in the abse

223 imer trap states in organic devices based on PMI derivatives.

224 , 0.2; P=.03), funisitis (RR, 0.4; P=.1), or PMI (RR undefined; P=.03).

225 (PMM2) and phosphomannose isomerase (MPI or PMI), respectively.

226 der and copy number, age and copy number, or PMI and copy number for each pair of variables.

227 The generalizability of our PMI findings was evaluated in a spontaneous myocardial i

228 P-PMI has an S1 lifetime (tauS) of 4.7 ns in toluene and 1

229 The porphyrin-perylene dyad P-PMI displays the most even spectral coverage from 400 to

230 e crenarchaeon Pyrobaculum aerophilum (PaPGI/PMI) has been determined in complex with glucose 6-phosp

231 isomerase from Pyrobaculum aerophilum (PaPGI/PMI) has been determined in native form at 1.16-A resolu

232 Thus, the PMI reaction in PaPGI/PMI probably uses a cis-enediol mechanism of catalysis,

233 able second base in the active site of PaPGI/PMI argues against a PMI mechanism involving a trans-ene

234 he glutamate base catalyst, shows that PaPGI/PMI uses the same catalytic mechanisms for both ring ope

235 09)Mdm2 and the nano-molar inhibitor peptide PMI.

236 ine (TPA), fluorene (Fl), perylenemonoimide (PMI), and perylenediimide (PDI) units have been successf

237 henylamine-oligothiophene-perylenemonoimide (PMI) molecules, denoted as BH4, on metal oxide surfaces

238 but not from that in umbilical cord plasma (PMI=53.9+/-10.6%; P>0.05), which contains mainly liver-d

239 he pre-specified protocol definition of PMI (PMI(Prot)) required a large elevation of creatine kinase

240 re evaluated in 8 malaria-naive primigravid (PMI) and 8 age-matched nulligravid (NMI) infected monkey

241 place of a glycine in PGI) may also promote PMI activity by positioning the C1-O1 region of M6P.

242 ptimal threshold for prognostically relevant PMI, confirmed in an internal validation cohort of 305 p

243 shold for diagnosing prognostically relevant PMI.

244 ure affect H2 generation, two representative PMI systems are investigated theoretically using a modif

245 ssociated with mortality than EXCEL and SCAI PMIs defined by isolated enzyme elevation when CK-MB was

246 apes to the exclusion of others using simple PMI plots.

247 In the EXCEL trial, the pre-specified PMI(Prot) was associated with similar hazard after PCI a

248 il sacrifice, on one of four diets: standard PMI Picolab Rodent Diet 20, a milk-free modification of

249 potent duodecimal peptide inhibitor, termed PMI (TSFAEYWNLLSP), of the p53-MDM2 and -MDMX interactio

250 so found that an extract of tarragon, termed PMI-5011, activated hypothalamic Klf4 and Agrp.

251 most potent inhibitor (TSFAEYWNLLSP), termed PMI, bound to MDM2 and MDMX at low nanomolar affinities-

252 peptide antagonists of MDM2 and MDMX termed PMIs, one of which, TSFAEYWALLSP, bound to MDM2 and MDMX

253 We estimate that PMI has prevented 185 million (95% CrI: 138 million, 230

254 Our model estimates that PMI has played a significant role in reducing malaria ca

255 Our findings reveal that PMI activity is essential for the survival of C. neoform

256 Here we show that PMI promotes mitochondrial respiration, leading to a sup

257 These data show that PMI skeletal muscles exhibit altered local Ca2+ signalin

258 The MAN1 gene, encoding for the PMI enzyme, was isolated and sequenced from C. neoforman

259 For the PMI(UD), troponins were used preferentially (available i

260 purpose of this study was to investigate the PMI rates according to various definitions, their clinic

261 harge transfer is not observed in any of the PMI dimers, and only a small triplet yield (<5%) is obse

262 mation due to the pai-pai interaction of the PMI units between the neighboring dye molecules.

263 lish the age could give an indication of the PMI.

264 In particular, the PMI-AzaBPDI and PDI-AzaBPDI dyads presenting low LUMO le

265 the active site of the enzyme shows that the PMI activity of this enzyme may be due to the additional

266 Thus, the PMI reaction in PaPGI/PMI probably uses a cis-enediol me

267 resentation that was rotated relative to the PMI.

268 ticles published from 1994 to 2013 using the PMI to assess the adequacy of analgesic therapy suggests

269 6 and 24-26 proceeded more rapidly with the PMI ligands 9-11, whereas 4-exo cyclizations 28 and 5-en

270 Additional displacement of the PMIs by a biphenyl spacer along the long axis prevents e

271 ive myocardial infarction (PMI), even though PMI is a major cause of mortality in patients undergoing

272 Reductions in funding to PMI could lead to large increases in the number of malar

273 s only expressed in a narrow window prior to PMI.

274 ceived a different (supplemental) treatment (PMI) to enhance effects of the primary treatment.

275 Importantly, the N8A mutation turned PMI into the most potent dual-specific antagonist of MDM

276 for a slip-stacked geometry in which the two PMI molecules are displaced along their long axes by one

277 lar for all-cause mortality and with varying PMI(UD) biomarker definitions.

278 the rest (86-93%) is catabolized to 3H2O via PMI.

279 In vivo, PMI-5011 increased Agrp promoter activity in luciferase-

280 h similar hazard after PCI and CABG, whereas PMI(UD) was strongly associated with mortality after CAB

281 to determine whether the mechanism by which PMI 5011 improves insulin signaling is through regulatio

282 Associations with PMI were determined by regression analysis.

283 s of MDMX and of pTyr99 MDMX in complex with PMI as well as modeling studies reveal that the phosphat

284 ynthetic MDM2 and MDMX, both in complex with PMI, at 1.6 A resolution.

285 , mortality was compared among patients with PMI not fulfilling additional criteria (ischemic symptom

286 mortality was comparable among patients with PMI not fulfilling any other of the additional criteria

287 Mortality seems comparable in patients with PMI not fulfilling any other of the additional criteria

288 heral plasma from controls and patients with PMI or spontaneous MI by quantitative multiple reaction

289 ce interval [CI], 5.7-12.0) in patients with PMI versus 1.5% (95% CI, 0.9-2.0) in patients without PM

290 In patients with PMI, in-hospital mortality was 9.4% and 3.5% in patients

291 5%) was significantly better than those with PMI and abnormal angiograms (74.9 +/- 2.9%; P<0.001 log-

292 s 7.3% and 2.9% in patients with and without PMI (P<0.001).

293 Five-year survival in patients without PMI (85.7 +/- 0.5%) was significantly better than those

294 s 1.5% (95% CI, 0.9-2.0) in patients without PMI (P<0.001).

295 showed similar outcomes to patients without PMI, whereas >40% was identified as the optimal threshol

296 Increased diastolic Ca(2+) release in wt-PMI cardiomyocytes was related to hyperphosphorylation o

297 NOD1 also prevented Ca(2+) mishandling in wt-PMI mice.

298 on (PMI) HF model evaluated in wild-type (wt-PMI) and Nod1(-/-) mice (Nod1(-/-)-PMI).

299 Compared with wt-PMI, hearts from Nod1(-/-)-PMI mice had better cardiac f

300 re N-inversion path of the isomerization (Z)-PMI <==> (E)-PMI revealed a remarkable stabilization due