ライフサイエンスコーパス: PTU

1 PTU alters ciliary-driven flow and disrupts the normal g

2 PTU and PU were found to be competitive inhibitors of AA

3 PTU exposure during gastrulation (stage 8-12.5) was iden

4 PTU is teratogenic during late blastula, gastrulation, a

5 PTU treatment also interfered with the myelination of la

6 PTU treatment did not arrest gonadal differentiation.

7 PTU-treated animals did not exhibit the extensive develo

8 hyroidism was induced by administering 0.04% PTU in drinking water for 3 months.

9 T(3), T(4), PTU, and TBBPA induced fluorescence changes with the low

10 ); pain-outcome: beta = 0.05, p = 0.014) and PTU (pain-exposure: beta = 0.43, p = 4.16 x 10(-8); pain

11 ), OUD (r(g) = 0.20, p = 1.50 x 10(-3)), and PTU (r(g) = 0.29, p = 8.53 x 10(-12)).

12 significantly different between control and PTU-treated fish, though no differences in bacterial loa

13 The determination of ETU and PTU was performed by high performance liquid chromatogra

14 Quantification limits obtained for ETU and PTU with the HPLC/DAD method were 7 and 16 mug kg(-)(1)

15 termine the teratogenic potential of MMI and PTU using a validated Xenopus tropicalis embryo model.

16 Muscle fibres from normal and PTU-treated rat hearts were reconstituted with two diffe

17 reconstituted muscle fibres from normal and PTU-treated rat hearts.

18 n T (TnT) isoform compositions in the PO and PTU samples were significantly different (P = 0.001), wi

19 e in cTnI phosphorylation between the PO and PTU samples.

20 d in the absence and presence of both PU and PTU.

21 th density and small arterioles in PTU-S and PTU-L (P<0.05 or greater for all of the above comparison

22 nsion in diastole was increased in PTU-S and PTU-L rats, but only PTU-L rats showed a significant inc

23 lic wall thickness were reduced in PTU-S and PTU-L rats.

24 al blood flow were reduced in both PTU-S and PTU-L rats.

25 (V(u)) in trabeculae from both untreated and PTU-treated rats (at maximal Ca(2+) activation), and F-a

26 Pase activity in HMM from both untreated and PTU-treated rats.

27 in t/t(PTU) (18.7+/-2.1 mN x mm(-2)) and +/+(PTU) (21.9+/-4.0 mN x mm(-2)), but maximum oscillatory w

28 Association between PTU in the child's presence and motor development, cogni

29 cluded if they examined associations between PTU in the presence of their apparently healthy children

30 ) myocardial blood flow were reduced in both PTU-S and PTU-L rats.

31 hydrotestosterone) was entirely prevented by PTU treatment.

32 a given plasmid DNA sequence to its cognate PTU, and assessed its performance using a sample of 1000

33 es could be assigned to a previously defined PTU, a number that reached 63% in well-known taxa such a

34 with abnormal LR symmetry observed following PTU exposure.

35 Spectral changes were observed for PTU binding to [CoCo(AAP)] and [CoZn(AAP)] but not for [

36 Testes from PTU-treated male tadpoles had seminiferous tubules and a

37 In contrast to the gonads, PTU did block morphological development of the larynx.

38 nology use in a child's presence (hereafter, PTU), often referred to as technoference, is a growing c

39 al importance of the modified base at Pol II PTUs within members of the kinetoplastid family.

40 II polycistronic transcription units (Pol II PTUs) throughout the T. brucei genome.

41 .03 % in PO hearts versus 0.98 +/- 0.01 % in PTU hearts of total TnT.

42 rnal diameter in systole increased by 40% in PTU-S and 86% in PTU-L.

43 systole increased by 40% in PTU-S and 86% in PTU-L.

44 iolar length density and small arterioles in PTU-S and PTU-L (P<0.05 or greater for all of the above

45 Chamber dilatation in PTU-L rats was due to series sarcomere addition, typical

46 rion performance and found to be impaired in PTU-exposed animals relative to controls.

47 ernal dimension in diastole was increased in PTU-S and PTU-L rats, but only PTU-L rats showed a signi

48 and systolic wall thickness were reduced in PTU-S and PTU-L rats.

49 uggest that the combined action of localized PTU toxicity and altered levels of circulating thyroid h

50 Embryos were exposed to 1 mM PTU (EC(50)=0.88 mM), 1 mM MMI, or vehicle control (wate

51 hen crosslinked into a MOF-polythiourea (MOF-PTU) composite material, maintaining the catalytic prope

52 This MOF-PTU hybrid material was spray-coated onto Nyco textile f

53 In the mouse, PTU treatment disrupts survival and differentiation of o

54 e able to assign plasmids to known and novel PTUs, based on their genomic sequence.

55 The remaining plasmids represent novel PTUs, indicating that a large fraction of plasmid backbo

56 1.2-fold) in the phagocytic cell activity of PTU-treated fish relative to the controls.

57 This article reviews the side effects of PTU and the literature on PTU-induced nephrotoxicity.

58 This study investigated the effects of PTU treatment, T(4) replacement therapy and thyroidectom

59 ity significantly decreased after 1 month of PTU treatment (30%) and remained at control levels with

60 ity significantly decreased after 1 month of PTU treatment (53%) and remained suppressed, despite the

61 nicians should be aware of the propensity of PTU to cause lupus-like syndromes with renal involvement

62 No moderating effects of the type of PTU exposure on any associations were found.

63 isense transcripts increase at boundaries of PTUs in the absence of TbMCM-BP.

64 he side effects of PTU and the literature on PTU-induced nephrotoxicity.

65 increased in PTU-S and PTU-L rats, but only PTU-L rats showed a significant increase in myocyte leng

66 Shared genetic liability to PAU, PTU, CUD, and OUD was characterized by a unidimensional

67 thylenethiourea (ETU) and propylenethiourea (PTU) in fruits and vegetables is presented.

68 Propylthiouracil (PTU) is an anti-thyroid drug that reportedly can impair

69 Propylthiouracil (PTU) is favored over methimazole (MMI) due to potential

70 Propylthiouracil (PTU), used to treat Graves' disease, occasionally induce

71 s by treatment with 0.025% propylthiouracil (PTU) for 6 weeks (PTU-S) and 1 year (PTU-L).

72 ning alpha-MHC isoform and propylthiouracil (PTU)-treated rat hearts containing beta-MHC isoform.

73 We determined if propylthiouracil (PTU)-induced hypothyroidismin hamsters (HH) altered dopa

74 roxine synthesis inhibitor propylthiouracil (PTU).

75 hydralazine, minocycline, propylthiouracil (PTU) and levamisole-adulterated cocaine.

76 (T(4))) or inhibitors (6-N-propylthiouracil (PTU), Tetrabromobisphenol A (TBBPA)) of the thyroid axis

77 inistration of 3 or 10 ppm propylthiouracil (PTU) to pregnant and lactating dams via the drinking wat

78 lerant of CBZ and received propylthiouracil (PTU), with good effect in 3.

79 hyroid hormone suppressant propylthiouracil (PTU) from < 1 to 30 days post hatch.

80 (ssTnI), were treated with propylthiouracil (PTU) to revert MHC expression from adult (alpha-MHC) to

81 ) sustained treatment with propylthiouracil (PTU).

82 in) and those treated with propylthiouracil (PTU; V3 myosin).

83 lae, and were given 0.02% n-propythiouracil (PTU) in their drinking water for 4 weeks.

84 development of thyroid cancer in Thrb(PV/PV)-PTU and untreated Thrb(PV/PV) mice.

85 reduced by approximately 42% in Thrb(PV/PV)-PTU mice as compared with Thrb(PV/PV) mice.

86 /PV) mice with propylthiouracil (Thrb(PV/PV)-PTU mice) and compared the development of thyroid cancer

87 ridine in thyroid tumor cells of Thrb(PV/PV)-PTU mice, indicative of decreased tumor cell proliferati

88 sing tumor cell proliferation in Thrb(PV/PV)-PTU mice.

89 s in apoptosis of tumor cells in Thrb(PV/PV)-PTU mice.

90 wcase the fast production of high-resolution PTU objects with disparate mechanical properties.

91 l repression of the specialized subtelomeric PTUs, the Bloodstream-form Expression-Sites (BESs), whic

92 maximum isometric tension was similar in t/t(PTU) (18.7+/-2.1 mN x mm(-2)) and +/+(PTU) (21.9+/-4.0 m

93 efficiency was significantly enhanced in t/t(PTU) (26.1+/-2.6%) compared with +/+(PTU) (17.1+/-1.6%).

94 ations occurred at higher frequencies in t/t(PTU) (7.31+/-1.17 Hz) compared with +/+(PTU) (4.48+/-0.6

95 cous load was significantly lower in the t/t(PTU) compared with +/+(PTU), ie, approximately 40% lower

96 (PTU)) and homozygous-truncated cMyBP-C (t/t(PTU)) mice starting at age approximately 8 weeks and lea

97 ontractile efficiency is enhanced in the t/t(PTU), probably through a reduced loss of mechanical ener

98 sitive to phosphate concentration in the t/t(PTU).

99 e +/+(PTU) and effectively absent in the t/t(PTU).

100 have important implications for women taking PTU during early pregnancy.

101 in other biological systems demonstrate that PTU can significantly alter glutathione S-transferase (G

102 f cardiac heavy meromyosin (HMM) showed that PTU treatment resulted in >40% reduction of ATPase activ

103 onfirmed that cMyBP-C was present in the +/+(PTU) and effectively absent in the t/t(PTU).

104 was resistant to thionamide alone (CBZ then PTU) and responded to adjunctive steroids.

105 -week diet of 0.15% 6-n-propyl-2-thiouracil (PTU) was fed to wild-type (+/+(PTU)) and homozygous-trun

106 1-Phenyl-2-thiourea (PTU) and urea (PU) were also examined to determine the d

107 hemical compounds (e.g. 1-phenyl-2-thiourea, PTU) or pigmentation mutant strains (e.g. casper mutant)

108 the rapid formation of poly(thiourethanes) (PTUs).

109 of circulating thyroid hormone contribute to PTU-mediated abnormalities in the olfactory system.

110 are consequent to localized toxicity due to PTU metabolism.

111 Exposure to PTU, but not MMI, led to cardiac and gut looping defects

112 2-thiouracil (PTU) was fed to wild-type (+/+(PTU)) and homozygous-truncated cMyBP-C (t/t(PTU)) mice s

113 sequences flanking the polycistronic units (PTUs) in T. cruzi.

114 The definition of plasmid taxonomic units (PTUs), based on average nucleotide identity metrics, all

115 ranged in Polycistronic Transcription Units (PTUs), which are demarcated by transcription start and s

116 ption and polycistronic transcription units (PTUs).

117 Unlike PTU-treated animals, crystal larvae are able to perform

118 alcohol use (PAU), problematic tobacco use (PTU), cannabis use disorder (CUD), and opioid use disord

119 ive) = 57,120), and problematic tobacco use (PTU, N(effective) = 270,120).

120 h 0.025% propylthiouracil (PTU) for 6 weeks (PTU-S) and 1 year (PTU-L).

121 Tadpoles treated with PTU for 50 or 100 days had larynges which structurally r

122 One month treatment with PTU revealed a significant decrease in expression of GST

123 in t/t(PTU) (26.1+/-2.6%) compared with +/+(PTU) (17.1+/-1.6%).

124 t/t(PTU) (7.31+/-1.17 Hz) compared with +/+(PTU) (4.48+/-0.60 Hz) and was significantly more sensiti

125 ntly lower in the t/t(PTU) compared with +/+(PTU), ie, approximately 40% lower at 1 Hz.

126 uracil (PTU) for 6 weeks (PTU-S) and 1 year (PTU-L).