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1 Po fat ingestion rapidly induces insulin resistance by r
2 Po vein insulin delivery, or strategies that mimic it (i
3 Po(2+) occurrence in low-to-neutral-pH waters is attenua
4 Po(gamma) curves had the midpoint at 5.5 +/- 0.1 dyne/cm
7 s between environmental exposure to (2)(1)(0)Po and human health effects were identified in a literat
9 evaluate environmental exposure to (2)(1)(0)Po and the biological effects of low-dose exposure to it
10 The radionuclide grandparents of (2)(1)(0)Po are common in sediments, and segments of the public m
11 hronically exposed to low levels of (2)(1)(0)Po in drinking water or in food products from animals ra
16 itivity and tendency to concentrate (2)(1)(0)Po, the ovary may be the critical organ in determining t
19 1 association with oxygen of 0.209 sec(-1) + Po(2) 2.07 x 10(-4) sec(-1)/mm Hg at 37 degrees C, and a
21 nsP3], ATP had dramatic effects on mInsP3R-2 Po, but unlike the rInsP3R-1, this did not occur by alte
22 d Am) for long-lived polonium isotopes ((208)Po, (209)Po, (210)Po) are effectively removed during pro
23 long-lived polonium isotopes ((208)Po, (209)Po, (210)Po) are effectively removed during processing.
28 s, lead-210 ((210)Pb) and polonium-210 ((210)Po) >= 1.0 and 0.7 pCi/L (picocuries per liter), respect
31 ha-emitting radon progeny Polonium-210 ((210)Po) in the olfactory epithelium, olfactory bulb, frontal
33 sequential determination of (90)Sr and (210)Po in food samples using ultra low-level liquid scintill
34 f stable strontium as yield tracer, and (210)Po is determined through self-deposition using (209)Po a
39 e also assessed the association between (210)Po levels and exposure parameters for urban air pollutio
40 able to detect the radiation emitted by (210)Po, an atypical clinical course prompted active consider
41 y the naturally occurring alpha-emitter (210)Po and that Fukushima-derived doses were three to four o
42 5 and from <13.6 to 233.3 Bq kg(-1) for (210)Po, (238)U, (232)Th and (40)K respectively, whereas they
44 ic status also had significantly higher (210)Po levels in lungs (coefficient = -1.19; standard error
46 its on radionuclides in foods including (210)Po and (90)Sr, two of the most important radionuclides f
49 ent's death established the presence of (210)Po at concentrations about 10(9)-times higher than norma
55 findings show that the concentration of (210)Po was associated with anthracosis in lungs of non-smoke
56 annual effective dose due to intake of (210)Po, (238)U, (232)Th and (40)K ranged from 280 and 800 mu
58 ured amounts and tissue distribution of (210)Po, it was estimated that the patient had ingested sever
61 alpha-particle-emitting radiochemical ((210)Po-citrate) and 2 anticancer drugs (daunomycin and doxor
62 food products of vegetable origin, the (210)Po activity concentration follows the trend: leafy veget
64 The committed effective doses due to (210)Po from ingestion of honey for infants, children and adu
67 re determined by alpha ((235)U, (238)U, (210)Po, (232)Th and (228)Th) and gamma spectrometry ((137)Cs
69 e-pCa relationship for forces less than 0.50 Po (maximum Ca2+-activated force), i.e. the Hill coeffic
70 -2 s-1) and constant up to approximately 50% Po, then rising sharply to a maximum (16 +/- 0.8 s-1) in
77 velocity, functional capillary density, and Po(2) in arterioles, venules, and extravascular tissue.
81 n Arabidopsis ecotypes Col-0 (resistant) and Po-1 (susceptible) revealed segregation of more than one
84 itions ( approximately 5 microM; channels at Po approximately 0.3) but not under diastolic Ca(2+) con
85 nnel open probability in the absence of ATP (Po(zero)) and a correlated decrease in sensitivity to in
87 or even more pronounced, than those between Po and ventro-posterior thalamic nucleus synapses in S1.
89 study conducted at Sannazzaro de' Burgondi (Po Valley), Italy, specifically aimed at optimizing the
91 Bmp and CaMKII increased L-type Ca2+ channel Po in a non-additive manner, suggesting that low and hig
95 in part due to an increase in single channel Po and that the cytoplasmic tails of the beta- and gamma
96 s, has a significantly higher single channel Po compared to the wild-type channel (0.85 vs 0.60, resp
99 also significantly higher, whereas choroidal Po(2) was significantly lower in the photocoagulated ret
103 xygen tension and consequently increased CSF Po(2) resulting from administration of high Fio(2) durin
105 o the conclusion that the mutation decreases Po by perturbing the gating conformational changes in CF
106 conclusion that the R117H mutation decreases Po by perturbing the gating conformational changes in CF
107 h elevated particulate Po (Po(p)): dissolved Po (Po(aq)) ratios in the cultures, consistent with effi
108 physiology to demonstrate that LP and dorsal Po cells exhibit a variety of responses to simple visual
109 responsive neurons across the LP and dorsal Po whose properties align with some of the established f
110 the open probability (Po.) is reversed, i.e. Po. increases as temperature is lowered whereas under hy
113 We found that Ang II acutely increases ENaC Po, whereas prolonged exposure to Ang II also induces tr
115 None of the enteric caliciviruses except Po/Sapo/GIII/Cowden/80/US replicates in cell culture, wh
117 oped less average peak Ca2+ activated force (Po) during fixed-end contractions (0.78 +/- 0.02 vs. 0.9
121 f the thalamus: the posterior nuclear group (Po), and a region located at the interface of the centra
122 us dog, insulin was infused into the hepatic Po vein or a peripheral (Pe) vein at a rate four times o
123 ry into both mode 1(low Po) and mode 2 (high Po) gating states and that these gating impairments can
125 one TRIC-B channels exhibit low Po, the high Po levels reached by multiple TRIC-B channels may provid
126 channels produced no significant changes in Po, nor did it restore the ability of RyRs to respond to
129 rated that mutant channels had a decrease in Po with 0.16 +/- 0.03 versus 0.67 +/- 0.07 for wild type
131 de that the functional defect (a decrease in Po) of DeltaF508-CFTR is as important as the trafficking
132 prevented the genistein-induced decrease in Po, but was without effect on the genistein-induced decr
134 microM Ca2+o had a 5- to 6-fold increase in Po which was accompanied by increases in both open times
135 in protocol 1 and fell faster in Pe than in Po, reaching 41 +/- 3 vs. 67 +/- 2 mg/dL (P < 0.01) by 6
136 the single channel currents had an increased Po compared to negative potentials which was associated
137 ogue 1-oleoyl-2-acetyl-sn-glycerol increased Po, but phorbol 12,13-dibutyrate, which stimulates prote
141 the boutons made in each area by individual Po axons, as well as in functionally-relevant parameters
143 at high altitude because of the low inspired Po(2), which is caused by the reduced barometric pressur
144 oelectrodes were used to record intraretinal Po(2) profiles from healed photocoagulation lesions in a
145 ur main result that HONO in the investigated Po Valley region is mainly from a gas-phase source that
149 mutation impedes entry into both mode 1(low Po) and mode 2 (high Po) gating states and that these ga
150 acic aorta from both rabbit and mouse at low Po(2) (approximately 1% O(2)) but not at high Po(2) (app
151 d, although lone TRIC-B channels exhibit low Po, the high Po levels reached by multiple TRIC-B channe
152 odel provided a better discrimination of low Po(2) than the tissue-to-plasma ratio or the k(3) of the
154 inhibitory peptide equalized TG and WT LTCC Po and eliminated EADs, whereas a peptide antagonist of
156 nnels was 0.13 +/- 0.02, with a half-maximal Po potential (Vo) of -28.7 +/- 1.4 mV for control record
158 ylinositol (4)5-kinase increased the maximal Po of both Kv7.2 and Kv7.2/7.3 channels studied in on-ce
159 on of muscarinic agonist reduced the maximal Po of Kv7.2/7.3 channels isolated in on-cell patches.
163 was calibrated in water phantoms at multiple Po(2) and temperature conditions (n = 10) and in ex vivo
166 l portions of the posterior thalamic nuclei (Po), multisensory processing of information related to a
169 igated the mouse Posterior thalamic nucleus (Po) cell axons that simultaneously innervate motor and s
175 The other resistance-determining genes of Po-1 can function, however, as they successfully conferr
176 nd RyR2 (sheep) with a maximal inhibition of Po (Emax) to 52 +/- 4% of control only after adding phys
177 3 currents was due to a strong inhibition of Po and a moderate suppression of single channel conducta
178 drolysis data, we proposed that recycling of Po in vegetative biomass residues is an important mechan
180 ly large differences between the synapses of Po versus ventral posteromedial thalamic nucleus axons i
181 ncreased the probability of channel opening (Po) sixfold, which was associated with an increase in th
183 ative potentials the probability of opening (Po) was low and the open time distributions were describ
187 troretinography (ERG) and preretinal oxygen (Po(2)) measurements were obtained 3 to 5 days before sur
193 ates exponentially with elevated particulate Po (Po(p)): dissolved Po (Po(aq)) ratios in the cultures
194 s and properties of soil organic phosphorus (Po) largely drive ecosystem productivity with increasing
195 evated particulate Po (Po(p)): dissolved Po (Po(aq)) ratios in the cultures, consistent with efficien
196 exponentially with elevated particulate Po (Po(p)): dissolved Po (Po(aq)) ratios in the cultures, co
197 In high-pH environments, aqueous polonium (Po) is poorly sorbed, occurring as dihydrogen polonate (
204 stablished multisensory features: posterior (Po), suprageniculate (Sg), limitans (Lim), and medial pu
205 gher-order neurons located in the posterior (Po), lateral posterior (LP), and lateral dorsal (LD) nuc
207 DeltaF508-CFTR targeting) and potentiator ("Po", normalizing DeltaF508-CFTR channel gating) activiti
211 5 mM increased the open channel probability (Po) of native RyRs in SR vesicles, but not of purified R
212 pproximately 13-fold lower open probability (Po ), were found with the R117H mutation that is associa
214 Delta33 showed an enhanced open probability (Po = 0.6 at -60 mV) and a reduced ATP sensitivity (Ki, 8
215 KATP channels had a higher open probability (Po = 0.7) and a lower ATP sensitivity (Ki = 196 microM)
216 ases the intrinsic channel open probability (Po(0)), thereby indirectly producing a marked decrease i
217 ctance, maximal achievable open probability (Po) and the [Ca2+] required for activation and inhibitio
221 L- and N-type Ca2+ channel open probability (Po) in cell-attached patches that contained a single cha
222 do not change the channel open probability (Po) in the absence of ATP, supporting the involvement of
224 porated into bilayers, the open probability (Po) of channels from Tric-a KO mice was markedly lower t
225 of red cell membranes, the open probability (Po) of the Gardos channel is markedly reduced when the t
226 onists, the single-channel open probability (Po) of the phenylalanine 508-deleted cystic fibrosis tra
227 >/=5 microM) increased the open probability (Po) of very active ("high-activity") RyR1 of SkM reconst
228 minal Ca(2+) dependence of open probability (Po) over the physiologically relevant range (0.05-1 mM C
229 (P-dATP), can increase the open probability (Po) to approximately 0.7, implying that the gating defec
230 evel, i.e., an increase in open probability (Po), and second, these C-terminal regions of beta- and g
236 wed us to obtain a maximum open probability (Po,max) value for the extrasynaptic receptors (Po,max =
237 perature dependence of the open probability (Po.) is reversed, i.e. Po. increases as temperature is l
239 activate EADs, and LTCC opening probability (Po) was significantly higher in TG than WT cardiomyocyte
241 ic (L596A/G/W/Q/K) reduces open probability [Po; loss-of-function (LOF)], likely due to altered inter
247 yperoxia increased the average inner retinal Po(2) (P(IR)) in the detached retina to a level higher t
251 o the luminal side of purified channels, RyR Po increased significantly; however, the channels still
252 mice marked differences between MC versus S1 Po synapses in (1) bouton and active zone size, (2) neur
254 The findings that individual dura-sensitive Po, LP, and LD neurons project to many functionally dist
256 T channel had indistinguishable steady-state Po values, ATP dose-response relationships and single-ch
259 conformation of Hb to tissue oxygen tension (Po(2)) and thereby provide a basis for the graded vasodi
262 educed by increasing temperature, as are the Po values of inside-out patches of Chinese hamster ovary
268 However, unlike channels from WT mice, the Po of SR K(+) -channels from Tric-a KO mice increased as
269 ics indicated that Ca2+ and ATP modulate the Po predominately by facilitating extended bursting activ
272 acterize the suburban and rural areas of the Po Valley and of other many populated environments.
274 a large body of evidence indicates that the Po(2)-coupled allosteric transition from R (oxy)-state t
275 s with cloned RPS2 alleles revealed that the Po-1 allele of RPS2 can function in a Col-0 genetic back
279 equence in Bay of Hangzhou (China) for their Po composition using solution (31)P-NMR after NaOH-EDTA
283 dolateral part of PPC (PtP) also projects to Po but can be distinguished from lPPC based on architect
290 ging protocol to image quantitative vitreous Po(2) noninvasively and evaluated effects from vitreal m
295 ble to those observed before disuse, whereas Po/CSA and unloaded shortening velocity reached a higher
296 at, although PPC subareas are connected with Po and medial LP, the medial and lateral secondary visua
298 otential new genogroup of porcine SaVs, with Po/SaV/OH-JJ681/00/US as the representative strain.
300 lucose fell faster with Pe insulin than with Po insulin, reaching 56 +/- 3 vs. 70 +/- 6 mg/dL (P = 0.