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1 ccompanying paper that mes-6 encodes another Polycomb group protein.
2 mes-2 encodes another Polycomb group protein.
3 also involved in epigenetic silencing by the Polycomb group proteins.
4 rs and epigenetic gene silencing mediated by Polycomb group proteins.
5 even in the presence of normal levels of all Polycomb group proteins.
6 al repressors: the gap gene products and the Polycomb group proteins.
7 silencing is mediated, at least in part, by Polycomb Group proteins.
8 Both silencing activities depend upon Polycomb Group proteins.
9 genes previously epigenetically silenced by Polycomb group proteins.
10 of chromatin-remodeling complexes, including Polycomb group proteins.
11 glycosylases and repressive targeting by the Polycomb group proteins.
12 lation of histone H3 on lysine 27 (H3K27) by Polycomb group proteins.
13 paternal and maternal genomes as well as by Polycomb group proteins.
14 keletal or chromatin tethers as well as with polycomb group proteins.
15 H3 at lysine 27 (H3K27me) as directed by the Polycomb group proteins.
16 core ES transcriptional circuitry, including Polycomb group proteins.
17 tions, expanding the regulatory diversity of polycomb group proteins.
18 ber of transcriptional repressors, including Polycomb-group proteins.
19 homologs of the Drosophila chromatin-binding Polycomb-group proteins.
20 basis of epigenetic maintenance mediated by Polycomb-group proteins.
21 e been identified that mediate the action of Polycomb-group proteins.
22 complex 1 (PRC1) comprise a core assembly of Polycomb group proteins and additional factors that incl
24 chromatin states mediated by the Drosophila Polycomb group proteins and is physically associated wit
25 t that, contrary to the prevailing view, the Polycomb group proteins and methyltransferase complexes
26 se genes are subjected to repression by both Polycomb group proteins and SetDB1, and loss of either r
28 generation of ChIP-seq data for SWI/SNF and Polycomb group proteins and the transcriptional represso
30 ypermethylation, recruitment, and binding of polycomb-group proteins, and histone heterochromatin mod
40 of the SC gene corona and depletion of other Polycomb group proteins are similarly associated with po
45 a link between an Abd-type Hox protein and a Polycomb group protein at the level of direct protein-pr
46 ver faster at sites for trithorax-group than polycomb-group protein binding, suggesting that nucleoso
54 MUC1-C regulated nuclear localization of the polycomb group proteins BMI1 and EZH2, which formed comp
55 suggest, more generally, that Trithorax and Polycomb group proteins can cooperate with one another t
64 sferase EHMT2 (also known as G9A) or for the Polycomb group protein EED, involved in repressive H3K9m
68 al germ cells (PGCs), (iii) highly express a polycomb group protein enhancer of zeste drosophila homo
70 through gene expression profiling, that the polycomb group protein enhancer of zeste homolog 2 (EZH2
71 ast cancer with heightened expression of the Polycomb group protein Enhancer of Zeste Homolog 2 (EZH2
75 encodes a protein similar to the Drosophila Polycomb group protein, Enhancer of zeste, and in the ac
77 otein, a mammalian homolog of the Drosophila Polycomb group protein Esc, as a bait in the yeast two-h
80 en-responsive elements (ARE) and dictated by Polycomb group protein EZH2 and repressive chromatin rem
81 ever, constitutive repression of CCN3 by the Polycomb group protein EZH2 disrupted this negative feed
82 4) in Genes & Development of the role of the polycomb group protein Ezh2 in muscle stem cells, and di
89 inase in FLB1 and a differentially localized Polycomb group protein Ezh2, which is mostly nuclear in
91 ogenesis is to suppress transcription of the Polycomb group protein, EZH2, thereby de-repressing gene
95 uces dorsal mesoderm by releasing repressive polycomb group proteins from chromatin, bound to the Sta
100 ng of DAB2IP is a key mechanism by which the polycomb-group protein histone-lysine N-methyltransferas
103 ur results suggest a role of Sfmbt and other Polycomb group proteins in downregulating the expression
104 results predict that the MES proteins, like Polycomb group proteins in Drosophila, function as a com
105 silent set of miRNA genes is co-occupied by Polycomb group proteins in ES cells and shows tissue-spe
107 the importance of histone methylation by the polycomb group proteins in the mouse circadian clock mec
109 sive complex 1-like), is composed of several Polycomb-group proteins including Ring1, Ring2, Bmi1 and
110 ver, we demonstrate that endogenous E2F6 and polycomb group proteins, including RYBP, Ring1, MEL-18,
112 ng protein homologous to Drosophila SFMBT, a Polycomb group protein involved in epigenetic regulation
113 ion of transcriptional silencing mediated by Polycomb group proteins is sufficient to induce an irrev
114 t the H2A-K119 ubiquitin E3 ligase Ring1b, a Polycomb group protein, is enriched on Xi in female trop
115 third thoracic segments, which requires the Polycomb group proteins, is disrupted by most chromosoma
116 miR-16 levels down-regulated BMI1 and other polycomb group proteins like RING1A, RING1B, EZH2 and al
118 by histone deacetylases and that mediated by polycomb group proteins may act either independently or
120 s provide a framework for an RNAi-dependent, Polycomb group protein-mediated heterochromatin formatio
121 trimethylation (H3K27me3) has been linked to polycomb-group-protein-mediated suppression of Hox genes
123 is study investigates the effect of Bmi-1, a polycomb group protein, on radiation-induced senescence
124 racterisation indicates that MEDEA encodes a Polycomb-group protein, particularly intriguing as MEDEA
126 ction of methylation-prone genes compared to Polycomb group protein (PcG) marking in embryonic stem c
127 biquitous transcription factor and mammalian Polycomb Group protein (PcG) with important functions fo
128 m chromatin and found candidates that impact polycomb group protein (PcG)-regulated gene expression i
129 ue of Molecular Cell) have demonstrated that Polycomb group proteins (PcG) and the Kcnq1ot1 regulator
139 strate that p53 influences expression of the Polycomb-group protein PHC1, which functions as a transc
141 eversible chromatin interactions mediated by Polycomb-group proteins play an important role in these
145 n of alternative fate genes by retaining the Polycomb Group protein Pleiohomeotic at Ubx targeted gen
146 g activity depends on a binding site for the Polycomb-group protein Pleiohomeotic (Pho) and on pho ge
147 e interaction between the SAM domains of the polycomb group proteins polyhomeotic (Ph) and Sex-comb-o
151 tioning in Arabidopsis thaliana We show that Polycomb-group proteins repress nucellus degeneration be
152 rotein interacts directly with E(Z), another Polycomb Group protein required for silencing of the hom
154 ingle-cell genome-wide interaction data on a polycomb-group protein, RING1B, and the associated trans
159 results indicate that combined modulation of polycomb group proteins, such as EZH2, along with TrxG p
160 The products of these genes are similar to Polycomb group proteins, suggesting possible mechanisms
161 es are a subset of those described for other Polycomb-group proteins, suggesting that E(Z) may also p
162 epress reporter gene expression and bind the Polycomb group protein SUZ12 and the DNA methyltransfera
163 strated that RA-mediated displacement of the polycomb group protein SUZ12 from a RARE was inhibited i
164 s including age-specific hypermethylation in polycomb group protein target genes and the upregulation
169 was correlated with higher levels of Bmi1, a polycomb group protein that is known to regulate the Ink
171 ransferase, Ezh2 (enhancer of zeste 2), is a Polycomb group protein that plays important roles in man
173 ubtypes and multiple myeloma, linked several polycomb group proteins that could be targeted by small
174 of bmi-1 is homologous to certain Drosophila Polycomb group proteins that regulate homeotic gene expr
176 lated by trans-acting factors related to the Polycomb-group proteins that have long been known as reg
177 e range of action of repressors, such as the Polycomb group proteins, throughout the euchromatic regi
178 Since E(Z) is required for binding of other Polycomb Group proteins to chromosomes, these results su
180 adian rhythms and extend the activity of the polycomb group proteins to the core clockwork mechanism
181 ransferases and repressing proteins, such as Polycomb group proteins; upon differentiation, DNMT acti
182 ensitive silencing are related properties of Polycomb-group proteins, whereas their activities are ge
183 on the mechanism of histone modification via Polycomb Group Proteins, which evolved in tandem with th
184 ereas VRN2 encodes a homologue of one of the Polycomb group proteins, which maintain the silencing of
185 he mark trimethyl H3K27, we examined whether Polycomb group proteins, which methylate H3K27, were pre
186 ppression as an alternative to regulation by Polycomb-group proteins, which coordinate embryonic germ
187 g how these configurations are stabilized by Polycomb group proteins will advance our understanding o