ライフサイエンスコーパス: QC

1 QC also suppressed phospho-NF-kappaB p65 more profoundly

2 QC calculations performed on some ruthenium model comple

3 QC data and experiments with 14 synthetic reference pept

4 QC precursor cells originated from the outer layer of st

5 QC ranges could not be established for nicotinamide (pyr

6 QC ranges were derived based on predefined, strict CLSI

7 QC ranges were established for 11 drugs: isoniazid (0.03

8 QC was more effective than HCQ at inhibiting the toll re

9 QC, GTE and GSE acted synergistically in combination wit

10 QC-01-175 also rescued stress vulnerability in FTD neuro

11 QC-01-175 effected clearance of tau in frontotemporal de

12 Two tier-2 QC reproducibility studies of bedaquiline DST were condu

13 We recommend using this software as a QC step in NGS studies in the clinical context.

14 We recommend using this software as a QC step in NGS studies.

15 We designed a QC pipeline involving hard filters to improve replicate

16 litized a strain of E. coli that expresses a QC-defective PheRS.

17 PG-QC formulations were prepared by mixing a QC ethanol solution with a PG aqueous solution followed

18 ity control of FASTQ files by carrying out a QC protocol using FastQC, parsing results, and aggregati

19 abolic feature are first established using a QC sample injected in serial injection volumes.

20 l ranges for zoliflodacin against additional QC strains were determined to be 0.12 to 0.5 mug/ml for

21 workflow allows for the analysis (alignment, QC, gene-wise counts generation) of raw RNAseq data and

22 acterium animalis subsp. lactis (BB 12); and QC, co-culture with the three probiotic microorganisms.

23 Although many analysis and QC tools have been reported, few combine ChIP-seq and DN

24 not chloroquine-sensitive) parasites, AO and QC increased the parasite's accumulation of, and suscept

25 In yeast, the endocytosis and QC of most plasma membrane (PM) proteins requires the Rs

26 Differential suppressive effects of HCQ and QC could also affect antimalarial responses in cutaneous

27 These methodologies and QC ranges will be submitted to CLSI and EUCAST to inform

28 to defects in the development of the RAM and QC.

29 ultifaceted tool suite to analyze, annotate, QC, and visualize the DNA methylation data.

30 After applying QC filtering based on Genome Analysis Tool Kit (GATK) be

31 With appropriate QC filters, WES can be used for PCA and adjustment for p

32 . mentagrophytes ATCC 28185 were selected as QC isolates, with an acceptable range of 0.12 to 1 mug/m

33 ate poorly water-soluble ingredients such as QC.

34 e time and effort must be spent on per-assay QC feature thresholding, and valid images and phenotypes

35 s and initiate mammalian ribosome-associated QC events remain undefined.

36 ivotal role in mammalian ribosome-associated QC pathways.

37 QC is a fast, light-weight, expression-based QC tool that detects outliers by implementing various st

38 ce, we developed iSeqQC, an expression-based QC tool that detects outliers either produced due to var

39 This inference-based QC will likely miss rare prerelease defects, and defects

40 es evidence that calculation of matrix-based QCs with various ISs could be applied for the selection

41 Both QC mechanisms distinguished the minute one-amino acid di

42 acceptance criteria for all analytes in both QC and real samples.

43 t ISs exhibited a poor data quality for both QCs and patients' concentrations.

44 tors that distinguish it from other cellular QC pathways.

45 organization, the onset of quiescent center (QC) formation during lateral root morphogenesis remains

46 The quiescent center (QC) of the Arabidopsis (Arabidopsis thaliana) root meris

47 y dividing cells named the quiescent center (QC), and, together, they form the stem cell niche (SCN).

48 in the elongation zone and quiescent center (QC), respectively.

49 The RM contains the quiescent center (QC), stem cells and frequently dividing meristematic cel

50 lation of cells called the quiescent center (QC).

51 m (RAM) size and defective quiescent centre (QC) development.

52 Meridian Bioscience Canada Inc, Quebec City, QC, Canada) is an automated real-time PCR assay for GAS

53 a high-resolution LC-MS method in commercial QC laboratories for product release and stability testin

54 S methods to modernize testing in commercial QC with more targeted control of product quality.

55 However, in DNA studies a common QC step is to check for unexpected relatedness between s

56 quality Control dasHbOard'), a comprehensive QC R-package.

57 The implementation of quantum computation (QC) would revolutionize scientific fields ranging from e

58 It contains QC metrics that are measured by default by the manufactu

59 g prevented upregulation of quantal content (QC), while leaving baseline release relatively unaffecte

60 R is rarely used in routine quality control (QC) analysis.

61 ectively, and comprehensive quality control (QC) and analysis tools are critical to extracting the mo

62 Phenotype selection, quality control (QC) and control of confounders are crucial and can have

63 be spent on pre-processing, quality control (QC) and normalization.

64 Both human serum based quality control (QC) and patient samples were quantified with a variety o

65 Rigorous organization and quality control (QC) are necessary to facilitate successful genome-wide a

66 was within +/-7.1% for all quality control (QC) concentrations.

67 RNA read depth (n = 3), or quality control (QC) failure with an external RNA control (n = 1).

68 ted and applied a number of quality control (QC) filters.

69 In E. coli, the quality control (QC) function of phenyalanyl-tRNA synthetase (PheRS) is r

70 ication of the z-factor for quality control (QC) in HTS studies.

71 tly identified 2 strains as quality control (QC) isolates for the method.

72 in GMP-compliant commercial quality control (QC) laboratories remains a challenge.

73 e acceptable limits at four quality control (QC) levels.

74 tion and <15% for all other quality control (QC) levels.

75 reticulum (ER) glycoprotein quality control (QC) machinery.

76 an sera exposed to OPNAs as quality control (QC) materials, the developed method successfully identif

77 ted in genetic studies as a quality control (QC) measurement.

78 a non-redundant set of five quality control (QC) measurements to establish a star rating system.

79 lly important mitochondrial quality control (QC) mechanism to selectively deliver damaged material to

80 a minimal model of the mRNA quality control (QC) mechanism.

81 However, the responsible quality control (QC) mechanisms remain poorly characterized.

82 ess is monitored by several quality control (QC) mechanisms that recognize defective translation comp

83 In addition, a quality control (QC) method suitable for DIA based on targeted MS/MS acqu

84 necessitates computer-aided quality control (QC) methodologies to flag imaging and staining artifacts

85 fforded by the conventional quality control (QC) methods.

86 Quality control (QC) metrics are critical in high throughput screening (H

87 We describe these and other quality control (QC) metrics from consensus data and explain how the CGES

88 Quality control (QC) metrics were evaluated over nine sequencing runs.

89 n-country establishment and quality control (QC) of a multiplex bead assay (MBA) for three sero-surve

90 hods for pre-processing and quality control (QC) of analytical data prior to statistical analysis has

91 toolkit for reference-free quality control (QC) of WGS reads and de novo genome assemblies, primaril

92 roval pathways but the same quality control (QC) paradigm, where the quality of released but untested

93 e (UPR), which is a protein quality control (QC) pathway in the endoplasmic reticulum that controls p

94 d protein response (UPR), a quality control (QC) pathway that operates in the endoplasmic reticulum (

95 However, quality control (QC) pathways for misfolded mitochondrial proteins remain

96 lved by ribosome-associated quality control (QC) pathways that oversee mRNA and nascent chain destruc

97 y do not provide a complete quality control (QC) pipeline.

98 generated from standardized quality control (QC) plasma samples and from real biological studies, the

99 a need to pass some form of quality control (QC) processing and checking before they can be used for

100 odologies and reference MIC quality control (QC) ranges for bedaquiline, a diarylquinoline antimycoba

101 to establish reference MIC quality control (QC) ranges for drug susceptibility testing of antimycoba

102 was performed to establish quality control (QC) ranges for the N. gonorrhoeae ATCC 49226 control str

103 tion MIC and disk diffusion quality control (QC) ranges were determined for cefepime-enmetazobactam.

104 Disk diffusion and MIC quality control (QC) ranges were determined for nafithromycin, a new lact

105 to support development and quality control (QC) release.

106 o downstream analysis using quality control (QC) reports.

107 this regard, we developed a quality control (QC) sample-based signal calibration workflow to overcome

108 In spiked quality control (QC) samples 82% of metabolite measurements had an interl

109 peated injections of pooled quality control (QC) samples distributed throughout each experiment demon

110 normalization performance, quality control (QC) samples, prepared from aliquots of all experimental

111 will be the only option for quality control (QC) starting in January 2016 if laboratories choose not

112 An important quality control (QC) step in these studies is to ensure that datasets fro

113 different, multilaboratory quality control (QC) studies that were used to establish QC ranges for th

114 A quality control (QC) study was performed to establish disk diffusion and

115 Quality control (QC) substrates are subsequently exported in distinct car

116 organelle-specific protein quality control (QC) systems.

117 use of MS-based methods for quality control (QC) testing of therapeutic proteins in a cGMP environmen

118 We developed a pipeline of quality control (QC) tests that were calibrated using systematic testing

119 lution pattern, alongside a quality control (QC) that serves as a reference in every run to facilitat

120 at's performance to similar quality control (QC) tools that utilize parallel programming and attained

121 GeCK-VISPR, a comprehensive quality control (QC), analysis, and visualization workflow for CRISPR scr

122 ns of study design and data quality control (QC), genotype imputation to augment available sequence d

123 hort GWAS studies including quality control (QC), imputation and downstream analyses.

124 (LC-MS)-based metabolomics, quality control (QC), molecular identification using MS/MS, data processi

125 use MAGeCKFlute to perform quality control (QC), normalization, batch effect removal, copy-number bi

126 After quality control (QC), we analysed 889 newly treated epilepsy patients usi

127 hodology for bioinformatics quality control (QC).

128 proposed to be an essential quality-control (QC) mechanism of pathophysiological relevance in mammals

129 Using strict CLSI criteria, QC ranges against the M. tuberculosis H37Rv reference st

130 al Laboratory Improvement Act (CLIA) default QC.

131 le of CNX in the hdeltaOR N-glycan-dependent QC.

132 ges by quality and more accurately determine QC cutoff thresholds.

133 We present the DIALib-QC (DIA library quality control) software tool for the s

134 k diffusion yielded inhibition zone diameter QC ranges that spanned 7 mm and encompassed 97.1% to 100

135 ons and quantum-chemical circular dichroism (QC-CD) calculations.

136 Nafithromycin disk diffusion QC ranges were determined to be 25 to 31 mm for S. aureu

137 he 7H9 broth microdilution MIC, a 3-dilution QC range (0.015 to 0.06 mug/ml) centered around the mode

138 For the agar dilution MIC, a 4-dilution QC range (0.015 to 0.12 mug/ml) centered around the geom

139 r package, scmeth, for a series of efficient QC analyses of large datasets.

140 f QC, which was related to the much-enhanced QC solubility.

141 ture are then calibrated to their equivalent QC injection volumes for comparative analysis.

142 es will no longer be able to use "equivalent QC" (EQC) or the Clinical and Laboratory Standards Insti

143 rol (QC) studies that were used to establish QC ranges for the novel gyrase inhibitor zoliflodacin ag

144 The established QC ranges will ensure that appropriate assay performance

145 Existing QC procedures help assess damage by simply plotting for

146 However, most of the existing QC instruments only allow processing of one sample at a

147 Five QC strains consistent with the spectrum of activity of n

148 NV, which provides an automated approach for QC and detection of rare CNVs that can facilitate equiva

149 hoose a statistically grounded criterion for QC in the HTS studies.

150 Few objective protocols exist for QC following variant calling from whole genome sequencin

151 ple transitions within a single manifold for QC remains unrealized in these high-spin species due to

152 ut combination screening there is a need for QC metrics that quantify the quality of combination resp

153 Average inter- and intraday precisions for QC samples were 7.5 and 5.3%, respectively.

154 A prominent proposal for QC relies on high-spin magnetic molecules, where multipl

155 d to conventional methods currently used for QC testing of protein therapeutics, such as CEX, HILIC,

156 ensitive to genotype error may be useful for QC.

157 pipeline features (i) technical and genomic QC in case-control and trio cohorts, (ii) genome-wide ph

158 liflodacin against the Neisseria gonorrhoeae QC strain ATCC 49226 was defined as 0.06 to 0.5 mug/ml a

159 The assay exhibited good QC parameters (Z'>0.5, S/B>2).

160 ation was significantly increased in the HCQ+QC group compared to HCQ group.

161 icantly higher in the HCQ group than the HCQ+QC group, the TNF-alpha level was higher in the HCQ+QC g

162 p, the TNF-alpha level was higher in the HCQ+QC group.

163 their response to antimalarials (HCQ vs. HCQ+QC).

164 Most reported HTS QC metrics are designed for plate level or single well l

165 nd to experimentally validate their roles in QC and CEI division.

166 pled with automated NMR and qHNMR for use in QC/QA efforts is established through case-based examples

167 n strategies, with reduction of variation in QC samples being the critical requirement for acceptance

168 fluorophore/quencher pair (IRDye 800CW/IRDye QC-1) with efficient contact quenching.

169 e associated with more CEI division but less QC division.

170 We present a novel cell-level QC workflow built on machine learning approaches for cla

171 Our cell-level QC workflow enables identification of artificial cells c

172 ce a predictive, interpretable, matrix-level QC metric, mQC, based on a mix of data-derived and heuri

173 Existing image- or patch-level QC methods require separate thresholds to be simultaneou

174 When combined with the plate-level QC metric, Z', mQC provides a more appropriate determina

175 tify problematic screens whereas plate-level QC was not able to.

176 Bedaquiline DST methodologies and MIC QC ranges against the H37Rv M. tuberculosis reference st

177 All disk diffusion and MIC QC ranges established in this study were approved by the

178 -defined tier 2 study, the agar dilution MIC QC range for zoliflodacin against the Neisseria gonorrho

179 Broth microdilution MIC QC ranges spanned 3 to 4 doubling dilutions and containe

180 Nafithromycin MIC QC ranges were determined to be 0.06 to 0.25 mug/ml for

181 These MIC QC ranges were also approved by CLSI for use in future i

182 mito-QC is an experimentally advantageous tool of broad relev

183 To address this, we have developed "mito-QC," a transgenic mouse with a pH-sensitive fluorescent

184 onfocal microscopy, we demonstrate that mito-QC is compatible with classical and contemporary techniq

185 rating that MDV formation is a mitochondrial QC operating in the heart.

186 outer membrane (MOM) proteins as novel model QC substrates in Saccharomyces cerevisiae.

187 The hetero-bifunctional molecule QC-01-175 was designed to engage both tau and Cereblon (

188 ranges for cefepime-tazobactam for multiple QC reference strains.

189 h to avoid these issues was proposed and new QC criteria under homoscedasticity were constructed so t

190 ts; 96.6% of all potential data points if no QC failures had occurred.

191 We conclude that de novo QC establishment in lateral root primordia operates via

192 We measured the antiplasmodial activities of QC, MB, and AO against chloroquine-resistant and chloroq

193 interactive visualization and exploration of QC and analysis results.

194 ia cell layer and perturbed the formation of QC precursor cells.

195 rogen bonding between the hydroxyl groups of QC and PG.

196 /1 compared with approximately 4.32mug/mL of QC alone.

197 lar uptake and transepithelial permeation of QC, which was related to the much-enhanced QC solubility

198 e is enhanced, and accuracy and precision of QC samples is increased.

199 ina sequencing machines makes the process of QC an onerous and time-consuming task that requires mult

200 R analyses showed a significant reduction of QC crystallinity upon formulating with PG that was assoc

201 ory gene, and ERF115 and PSK5, regulators of QC division, is increased in sav6 mutants.

202 division and suggests that SHR repression of QC division depends on formation of the SHR homodimer.

203 MAGeCK-VISPR defines a set of QC measures to assess the quality of an experiment, and

204 Finally, QuickMIRSeq generates a rich set of QC metrics and publication-ready plots.

205 o QC ratios were prepared; the solubility of QC reached 241.76mug/mL at PG/QC ratio of 30/1 compared

206 ddition, our model established the timing of QC and CEI division and suggests that SHR repression of

207 to bind to PfCRT(Dd2), and the transport of QC and MB via this protein was saturable and inhibited b

208 sicle refilling, homeostatic upregulation of QC is no longer observed.

209 This suggested that the upregulation of QC was due to mobilization of a distinct pool of vesicle

210 ajor pool during homeostatic upregulation of QC.

211 elease following homeostatic upregulation of QC.

212 However, both accuracy and precision of QCs and patient's concentrations showed significant corr

213 Our QC pipeline removes many potentially false positive call

214 Our QC workflow automatically handles assay-specific phenoty

215 We evaluated our QC pipeline with both large collections of public ChIP-e

216 est panel MRSA genomes, 168/173 (97%) passed QC metrics based on the correct species assigned, detect

217 Thus, when performing QC assessment using these two measures, care must be tak

218 PG-QC formulations were prepared by mixing a QC ethanol sol

219 PG-QC formulations with various PG to QC ratios were prepar

220 ll monolayer permeation tests showed that PG-QC formulations resulted in substantially enhanced cellu

221 solubility of QC reached 241.76mug/mL at PG/QC ratio of 30/1 compared with approximately 4.32mug/mL

222 When examined with protein-spiked plasma QC, peptide-level calibration exhibited severe negative

223 tion of PM proteins that escape or bypass PM QC systems.

224 des software for the import, pre-processing, QC and visualization of metabolic phenotyping datasets,

225 Proper QC of phenotypes before proceeding to the association an

226 During post PT QC, only RF2 (and not RF1) effectively binds to mismatch

227 factors in canonical termination and post PT QC.

228 unctions as the principle factor for post PT QC.

229 ng for API quality assurance and control (QA/QC).

230 erence materials and samples from several QA/QC studies, which were previously analyzed by EI HRGC/HR

231 rmalization, and in maintaining long-term QA/QC audits.

232 interactions, and novel ones, such as QuASAR-QC, to identify low-quality experiments.

233 de Cardiologie et de Pneumologie de Quebec, QC, Canada.

234 o improve the water solubility of quercetin (QC).

235 ions of lettuce extract (LE) with quercetin (QC), green tea extract (GTE) or grape seed extract (GSE)

236 her hydroxychloroquine (HCQ) and quinacrine (QC) differentially suppress inflammatory cytokines.

237 have been used to treat malaria (quinacrine [QC] and methylene blue [MB]) or to study P. falciparum (

238 iates a dashboard with plots of the relevant QC outcomes.

239 n, our data indicates that mQC is a reliable QC filter that can be used to identify problematic drug

240 f the remaining features within the repeated QC sample measurements demonstrated median peak area RSD

241 ned distance from the root tip by repressing QC-specific gene expression via the ACR4/CLV1 receptors

242 Establishment of lateral root QCs coincided with this developmental phase transition.

243 based on using quality control pool samples (QC).

244 f high-spin species as a pathway to scalable QC systems within magnetic molecules.

245 n, in principle, adequately replace selected QC methods and would add value to the in-process control

246 nal skills and which enable quick and simple QC and data extraction from MinION runs.

247 he number of features while retaining spiked QC compounds; however, a combination of approaches was n

248 WOX5 thus suppresses QC divisions that are otherwise promoted by CYCD3;3 and

249 The cefepime-tazobactam QC ranges for a fixed tazobactam MIC of 8 mug/ml and dis

250 The QC ranges established in this study should be used for d

251 The QC reference strain was Mycobacterium tuberculosis H37Rv

252 monstrate how the length of mRNA affects the QC process.

253 bacterium tuberculosis H37Rv was used as the QC reference strain.

254 ake these considerations into account at the QC stage will bias any following analysis.

255 ned insight into the differences between the QC and the cortex endodermis initials (CEI) by studying

256 intained in an undifferentiated state by the QC-expressed transcription factor WUSCHEL RELATED HOMEOB

257 proposed that WOX5 protein movement from the QC into CSCs is required for CSC maintenance, and that t

258 The stem cells distal from the QC, the columella stem cells (CSCs), are maintained in a

259 f the QC by excluding CYCD activity from the QC.

260 Determining how the QC regulates the surrounding stem cell initials, or what

261 Qualimap 2 represents a next step in the QC analysis of HTS data.

262 rential equation model of SHR and SCR in the QC and CEI which incorporated the stoichiometry of the S

263 -elongation zone, but represses genes in the QC and surrounding stem cells, and that BR and auxin hav

264 nosteroid (BR)-mediated cell division in the QC cells.

265 reover, ectopic expression of CYCD3;3 in the QC is sufficient to induce cell division in the QC.

266 tion behind some methods failing when in the QC laboratories.

267 In the QC study, 4 of the 6 ATCC strains showed interlaboratory

268 We propose that WOX5 acts mainly in the QC, where other short-range signals are generated that n

269 romoter to repress CYCD3;3 expression in the QC.

270 is sufficient to induce cell division in the QC.

271 unding stem cell initials, or what makes the QC fundamentally different from the actively dividing in

272 initiating and maintaining quiescence of the QC by excluding CYCD activity from the QC.

273 ccuracy (% bias) and precision (% CV) of the QC results at eight concentration levels (0.01, 0.02, 0.

274 ings indicate that when m-Tyr has passed the QC checkpoint by the PheRS, this toxicity of m-Tyr may r

275 ella-derived CLE40 signal is to position the QC at a defined distance from the root tip by repressing

276 nt is a graphical platform to streamline the QC of DNA sequencing data, to store these data for futur

277 We speculate that the QC pathways broadly regulate signaling glycoproteins and

278 dermophyton floccosum were tested, while the QC study tested 6 blinded T. rubrum or T. mentagrophytes

279 tical safety, we suggest transitioning their QC from inference- to verification-based practice by dev

280 These QC measures reflect known differences in sequencing prot

281 These QC ranges will be important for accurate in vitro activi

282 asets resulted in guidelines for using these QC metrics across a wide range of sequencing depths and

283 This QC range will be used for in vitro susceptibility testin

284 f CNV burden on T1D risk resulting from this QC pipeline converged on unity, suggesting no global fre

285 gates, consistent with the operation of this QC mechanism in the absence of ribosomal protein overexp

286 roach with data readout highly comparable to QC methods, while differences were observed for charge i

287 Our method is a simple but robust method to QC and speculates BCR for WGBS experiments to make sure

288 educed the susceptibility of the parasite to QC, MB, and AO.

289 PG-QC formulations with various PG to QC ratios were prepared; the solubility of QC reached 24

290 n according to feature intensity response to QC sample dilution.

291 HCQ refractoriness and a better response to QC.

292 T(D10)) variants of the protein to transport QC, MB, and AO when expressed at the surface of Xenopus

293 This study reveals a unique QC pathway comprised of a combination of cytosolic and m

294 s gap as a user friendly, interactive visual QC report that generates and concisely summarizes statis

295 e with d-symmetry form factor and wavevector QC = QP coexists with a d-symmetry superconductor; it is

296 Subarctic taiga (Kuujjuarapik-Whapmagoostui, QC) and a continuous permafrost region in the Arctic tun

297 aneous lupus erythematosus patients, whereas QC and HCQ inhibited IFN-alpha equally.

298 nsitive P. falciparum and determined whether QC and AO affect the accumulation and activity of chloro

299 hlight the existence of checkpoints at which QC substrates are selected for Golgi export and lysosoma

300 oxidation of peroxidating liposomes and with QC showing the largest effect.