ライフサイエンスコーパス: RNA helicase

1 factors, including Mpp6, Rrp47, and the Mtr4 RNA helicase.

2 rbour a targetable requirement for the eIF4A RNA helicase.

3 t on sigB and cshA, which encodes a DEAD box RNA helicase.

4 a cold-inducible DEAD (Asp-Glu-Ala-Asp) box RNA helicase.

5 p68 RNA helicase is a prototypical RNA helicase.

6 that regulates DHX9 and, potentially, other RNA helicases.

7 ely and negatively by multiple host DEAD-box RNA helicases.

8 n observed for many double-stranded DEAD-box RNA helicases.

9 IVa, reminiscent of the "arginine clamp" of RNA helicases.

10 A is strongly homologous to that in DEAD-box RNA helicases.

11 ments are largely driven by eight DExD/H-box RNA helicases.

12 ss of neurodevelopmental disorders involving RNA helicases.

13 anism is clearly different to those of other RNA helicases.

14 box RNA helicase DDX21 (also named nucleolar RNA helicase 2) is a nuclear autoantigen with undefined

15 ve identified the DEAD (Asp-Glu-Ala-Asp) box RNA helicase 24 (DDX24) as a novel regulator of the p300

16 pectrometry analysis identified the DEAD-box RNA helicase 6 (DDX6) that interacts with the VEGF mRNA

17 l proteins and ribonucleoproteins, including RNA helicase A (DHX9), Y-box binding protein (YBX1), DDX

18 Nuclear RNA helicase A (DHX9/RHA) is necessary for the translati

19 RNA helicase A (RHA) is a DExH-box RNA helicase that pla

20 DHX9/RNA helicase A (RHA) is a host RNA helicase that partici

21 n interactions, including helicases DDX5 and RNA helicase A (RHA) that alters RNA-splicing ratios.

22 e elucidated a unique unwinding mechanism of RNA helicase A (RHA) that entails discrete substeps cons

23 olecular basis for the incorporation of DHX9/RNA helicase A (RHA) to virions remains unclear.

24 ranslational control protein 80 (TCP80), and RNA helicase A (RHA), which positively regulate p53 IRES

25 Interestingly, RNA helicase A and La autoantigen relocated from a nucle

26 ck protein 70), estrogen receptor alpha, and RNA helicase A.

27 Inhibiting the eIF4A RNA helicase, a component of the eIF4F translation initi

28 oth Chtop and Alyref activate the ATPase and RNA helicase activities of Uap56 and that Uap56 function

29 l protein 2 (nsP2) exhibits the protease and RNA helicase activities that are required for viral RNA

30 Purified CshA exhibits typical RNA helicase activities, as exemplified by RNA-dependent

31 coactivate its targets depends on intrinsic RNA helicase activity and binding of a conserved nuclear

32 s with complex 5'UTRs require enhanced eIF4A RNA helicase activity for translation.

33 ernative splicing of target exons due to the RNA helicase activity of DDX17.

34 Ezrin inhibited the RNA helicase activity of DDX3 but increased its ATPase a

35 Our results support a model in which MOV10L1 RNA helicase activity promotes unwinding and funneling o

36 that RNase R contains an unusual, intrinsic RNA helicase activity that facilitates degradation of du

37 enzyme possesses an intrinsic, ATP-dependent RNA helicase activity that is essential in vitro for eff

38 r cells was also inhibited by blocking eIF4A RNA helicase activity with silvestrol and CR-1-31-B.

39 DDX3X missense mutations profoundly disrupt RNA helicase activity, induce ectopic RNA-protein granul

40 The addition of compounds that altered RNA helicase activity, induced oxidative stress, or stim

41 HDC2 is an RNA-induced ATPase with a 3'-->5' RNA helicase activity.

42 It contains the characteristic RNA helicase activity.

43 ctive conformation of eIF4A required for its RNA helicase activity.

44 d cytoplasm by a mechanism that requires its RNA helicase activity.

45 Mtr4 is a conserved Ski2-like RNA helicase and a subunit of the TRAMP complex that act

46 inding protein 4E-Transporter, the Xp54/DDX6 RNA helicase and additional RNA-binding proteins.

47 of human up-frameshift protein 1 (hUPF1), an RNA helicase and master regulator of NMD, in these disor

48 Recently, our group established the DEAD-box RNA helicase and microRNA (miRNA) microprocessor accesso

49 rations in Hippo, mTOR, histone methylation, RNA helicase and p53 signaling pathways in MPMs.

50 nes known to modulate TE expression, such as RNA helicases and autophagy genes.

51 n be partially reversed by overexpression of RNA helicases and can be fully overcome upon UV stress,

52 DEAD-box proteins are nonprocessive RNA helicases and can function as RNA chaperones, but th

53 RNA helicases and E3 ubiquitin ligases mediate many crit

54 n unexpected interdependence between the two RNA helicases and eIF4G, and suggest that Ded1p is an in

55 he DDX5-RORgammat complex reveals a role for RNA helicases and lncRNAs in tissue-specific transcripti

56 xplanation for the ATP-gated behavior of SF2 RNA helicases and receptor proteins.

57 ionary history of two types of viral sensor, RNA helicases and Toll-like receptors.

58 lar rules of engagement may apply to diverse RNA helicases and TRIM/TRIM-like proteins.

59 narily conserved rules of engagement between RNA helicases and tripartite motif (TRIM) E3 ligases tha

60 NS3 has NS2B-dependent protease, RNA helicase, and 5'-RNA triphosphatase activities.

61 protein 4 (PDCD4), an inhibitor of the eIF4A RNA helicase, and contributes to the induction of MUC1-C

62 lices, oligomerizes to function as efficient RNA helicase, and does not unwind DNA duplexes.

63 four major components: RNase E, PNPase, RhlB RNA helicase, and enolase.

64 3Kshort right arrowAKT pathway and the eIF4A RNA helicase, and that this response promotes EGFR signa

65 Here, we identify the conserved RNA helicase Aquarius/EMB-4 as a direct and essential li

66 al mouse challenge, we demonstrate here that RNA helicases are critical for IFN production by immune

67 RNA helicases are essential for virtually all cellular p

68 RNA helicases are involved in almost every aspect of RNA

69 Two UAP56/DDX39B RNA helicases are juxtaposed at each end of the tetramer

70 The activities of eight RNA helicases are required for pre-mRNA splicing.

71 Here, we show that several DEAD-box RNA helicases are sensitive to AMP, which is not produce

72 DEAD-box RNA helicases are vital for the regulation of various as

73 d identified DDX5, an ATP-dependent DEAD-box RNA helicase, as a component of the MAML1 protein comple

74 MTR4 is a RNA helicase associated with a nuclear exosome that play

75 The DEAH (Asp-Glu-Ala-His) box RNA helicase associated with AU-rich element (RHAU) (als

76 RNA helicase associated with AU-rich element (RHAU) is a

77 RNA helicase associated with AU-rich element (RHAU), a m

78 nscript and the phosphorylation of UPF-1, an RNA helicase associated with nonsense-mediated mRNA deca

79 The DHX36 RNA helicase associated with the Aven complex and was re

80 irus 10, homolog (MOV10) is an IFN-inducible RNA helicase, associated with small RNA-induced silencin

81 ches, we have determined the relation of the RNA helicase, ATP binding, and nuclease activities of RN

82 genetic factors, telomeric proteins, and the RNA helicase, ATRX.

83 activity of specialized helicases including RNA helicase AU (associated with AU rich elements) (RHAU

84 The RNA helicase bad response to refrigeration 2 homolog (BR

85 Brr2 is an RNA helicase belonging to the Ski2-like subfamily and an

86 zation and regulation as in the spliceosomal RNA helicase Brr2.

87 ties of human DDX3X are typical for DEAD-box RNA helicases, but diverge quantitatively from its highl

88 ortantly, we identify the conserved DEAD-box RNA helicase, CGH-1/DDX6, as a key CK2 substrate within

89 luding cohesins, condensins, topoisomerases, RNA helicases, chromatin remodelers, and modifiers-that

90 elix is particularly extensive for Ski2-like RNA helicases compared to related helicases.

91 ily requires the activity of a superfamily 2 RNA helicase contained in the C-terminal domain of nonst

92 oting effect of CDS methylation requires the RNA helicase-containing m(6)A reader YTHDC2.

93 Members of the DEAD-box family of RNA helicases contribute to virtually every aspect of RN

94 ese results suggest a role for the bacterial RNA helicase CrhR in RNase E-dependent mRNA processing i

95 ntified among multiple proteins the DEAD box RNA helicase CshA (NWMN_1985 or SA1885) by mass spectros

96 ur laboratory demonstrated that the DEAD-box RNA helicase Dbp2 in Saccharomyces cerevisiae is require

97 The evolutionarily conserved RNA helicase Dbp2 regulates formation of these R-loops a

98 In yeast strains lacking the RNA helicase, DBP2, or the RNA decay enzyme, XRN1, we fi

99 DEAD-box RNA helicase Dbp4 is required for 18S rRNA synthesis: ce

100 ect RNA chaperones, including three DEAD box RNA helicases (DBRHs) (CsdA, SrmB, RhlB) and the cold sh

101 DEAD-box RNA helicases (DBRHs) modulate RNA secondary structure,

102 f target genes of this complex including the RNA helicase DDX18.

103 DEAD-box RNA helicase DDX21 (also named nucleolar RNA helicase 2)

104 Here we show that the DEAD-box RNA helicase DDX21 can sense the transcriptional status

105 We show that PRL3 binds to the RNA helicase DDX21, thereby restricting productive trans

106 ion in pre-40S complexes is regulated by the RNA helicase DDX21.

107 ese genes ribosomal protein RPL35A, putative RNA helicase DDX24, and coatomer complex I (COPI) subuni

108 RNA helicase DDX3 has oncogenic activity in breast and l

109 The RNA helicase DDX3 is a component of neuronal granules, a

110 ted direct interaction between ezrin and the RNA helicase DDX3, and NSC305787 blocked this interactio

111 Here, we identified the RNA helicase DDX39B as a potent activator of this exon a

112 De novo germline mutations in the RNA helicase DDX3X account for 1%-3% of unexplained inte

113 subtypes of this disease, and nominates the RNA helicase DDX3X as a component of pathogenic beta-cat

114 The human DEAD-box RNA helicase DDX3X is an essential cofactor for viral re

115 The DEAD-box RNA helicase DDX3X is frequently mutated in pediatric me

116 The ubiquitous ATP-dependent RNA helicase DDX3X is involved in many cellular function

117 Five host RNA helicases (DDX3X, DDX5, DHX9, DHX37, DDX52) were inh

118 carcinoma cells, we identified the DEAD-box RNA helicase DDX41 as a novel regulator of p21 expressio

119 ts interaction with nucleophosmin (NPM/B23), RNA helicase DDX5 and RNA polymerase I transcription ter

120 The RNA helicase DDX5 is expressed by spermatogonia but role

121 The RNA helicase DDX5, and E3 ligase Mex3b, are important ce

122 Here, we show that suppression of the RNA helicase DDX6 endows human and mouse primed embryoni

123 The human RNA helicase DDX6 is an essential component of membrane-

124 Here, we show that the DEAD box RNA helicase, DDX6 is necessary for maintaining adult pr

125 Here we identify the RNA helicase DEAD-box protein 5 (DDX5) as a RORgammat pa

126 se G or by mutation of the gene encoding the RNA helicase DeaD.

127 Herein, we identified the RNA helicase, DEAD box protein 5 (DDX5), as a regulator

128 We show that two DEAD-box RNA helicases, DeaD and SrmB, activate csrB/C expression

129 Yeast DEAD-box RNA helicase Ded1 appears to promote translation by reso

130 Here we report an eIF4A RNA helicase-dependent mechanism of translational contro

131 Previously, we showed that the DEAH/RHA RNA helicase Dhr1 dislodges U3 from the pre-rRNA.

132 y with the box C/D snoRNA U3-associated DEAH RNA helicase Dhr1 supposedly involved in central pseudok

133 Nlrp6 bound viral RNA via the RNA helicase Dhx15 and interacted with mitochondrial ant

134 Here, we identified the RNA helicase DHX15 as a novel AR co-activator using a ye

135 ed as anti-viral, while three other cellular RNA helicases (DHX29, DHX35, RIG-I) were identified as p

136 y, Mitoma et al. (2013) demonstrate that the RNA helicase DHX33 binds to cytosolic dsRNAs to trigger

137 The RNA helicase DHX33 has been found to be overexpressed in

138 The RNA helicase DHX33 has been shown to be a critical regul

139 and increases the stability of the DEAH-box RNA helicase DHX33, which is critically involved in ribo

140 that a recently characterized DEAD/DEAH box RNA helicase, DHX33, promotes mRNA translation initiatio

141 In recent times, the RNA helicase DHX34 was found to promote mRNP remodelling

142 on and degranulation screens converged on an RNA helicase Dhx37.

143 EWS-FLI1 protein interacts with the RNA helicase DHX9 and affects transcription and processi

144 we show that PRRSV N interacts with cellular RNA helicase DHX9 and redistributes the protein into the

145 IGF2 mRNA, enhancing the association of the RNA helicase DHX9 to the IGF2 transcript and promoting I

146 Our data show that, via RNA helicase Dhx9, Nlrp9b recognizes short double-strand

147 The Brr2 RNA helicase disrupts the U4/U6 di-small nuclear RNA-pro

148 ction in RNA metabolism (Topoisomerase 1 and RNA helicases), DNA repair/replication processes (PARP1,

149 First, coexpression of the CH domain and the RNA helicase domain in trans can reconstitute Upf1 funct

150 eine- and histidine-rich (CH) domain and the RNA helicase domain of yeast Upf1 can engage in two new

151 pressed by silencing of Dicer-2, which has a RNA helicase domain similar to MDA5 that senses unedited

152 inserted in between the RecA modules of the RNA helicase domain.

153 and functionally interacts with the DEAH-box RNA helicase Ecm16 (also known as Dhr1).

154 DEAD-box RNA helicases eIF4A and Ded1 are believed to promote tra

155 We also found that an RNA helicase, eIF4A, independently accelerated eIF4E-cap

156 n initiation involves two conserved DEAD-box RNA helicases, eIF4A and Ded1p.

157 The RNA helicase eIF4A1 is a key component of the translatio

158 We define the RNA helicase eIF4A2 as the key factor of eIF4F through w

159 The putative RNA helicase encoded by the Arabidopsis gene At1g32490 i

160 t aspects of RNA metabolism involve DEAD-box RNA helicases, enzymes that bind and remodel RNA and RNA

161 is of single fluorescent Dbp5 molecules, the RNA helicase essential for mRNA export, revealed that Db

162 DEAD-box RNA helicases eukaryotic translation initiation factor 4

163 is specific member of the DEAD-box family of RNA helicases expressed in meiotic and haploid germ cell

164 tigated the potential function of DExD/H-box RNA helicase family members (previously shown to sense c

165 The recently discovered RNA helicase family of RIG-I-like receptors (RLRs) is a

166 (DDX5) is a founding member of the DEAD-box RNA helicase family, a group of enzymes that regulate ri

167 one of the founding members of the DEAD-box RNA helicase family, is extremely proficient at unfoldin

168 RQC-trigger (RQT) subcomplex composed of the RNA helicase-family protein Slh1/Rqt2, the ubiquitin-bin

169 -terminal domain followed by a superfamily 1 RNA helicase fold.

170 Caenorhabditis elegans protein LAF-1, a DDX3 RNA helicase found in P granules, phase separates into P

171 Vasa is a conserved RNA-helicase found in the germ lines of all metazoans te

172 in kinase 1a (CK1a), and the FRQ-interacting RNA Helicase (FRH) rhythmically represses gene expressio

173 complex of Frequency (FRQ), FRQ-interacting RNA helicase (FRH), and casein kinase I (CKI), which inh

174 FRQ in turn binds to FREQUENCY-Interacting RNA Helicase (FRH), whose clock function has been assume

175 -mediated decay (NMD) by preventing the UPF1 RNA helicase from associating with potential decay targe

176 may be general mechanisms for regulation of RNA helicase functions.

177 remodeling is achieved is largely limited to RNA helicase functions.

178 tified recurrent mutations in the DEAD/H-box RNA helicase gene DDX41 in familial and acquired cases o

179 We identified an RNA helicase gene, DDX3 (DDX3X), which is overexpressed

180 nes impacting protein synthesis: a ribosomal RNA helicase gene, tRNA biosynthesis genes, and a gene c

181 Loss of CGH-1/Ddx6 RNA helicase generates solid granules that are sensitive

182 DDX41 is exemplary of other RNA helicase genes also affected by somatic mutations, s

183 ave probably damaging variants in DExD/H-box RNA helicase genes.

184 Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) is a testis specific member of

185 DDX3, an RNA helicase, has widespread functions in RNA regulation

186 mber of the ATP-dependent DEX(H/D) family of RNA helicases, has been established as a major cellular

187 atory role of LANA and identified a cellular RNA helicase, hnRNP A1, regulating the translation of LA

188 RNA helicases impact RNA structure and metabolism from t

189 We reported earlier that LAF-1, a DEAD box RNA helicase in C. elegans, dynamically interacts with R

190 and ATP-dependent roles of the Has1 DEAD-box RNA helicase in consecutive pre-rRNA processing and matu

191 mode of regulation of snoRNP function by an RNA helicase in human cells.

192 and provide evidence implicating a mammalian RNA helicase in RNA modification and Pol II elongation c

193 encoding the sole Asp-Glu-Ala-Asp (DEAD)-box RNA helicase in Synechocystis sp. PCC 6803, crhR (slr008

194 DHX33 is a pivotal DEAH-box RNA helicase in the multistep process of RNA polymerase

195 ngly, we also show that Dbp2 is an efficient RNA helicase in vitro and that Yra1 decreases the effici

196 NOD)-like receptors and DEAD-box or DEAH-box RNA helicases in an orchestrated RNA-sensing network and

197 Our work implicates distinct RNA helicases in specific steps along the nuclear piRNA

198 anism of NMD with an emphasis on the role of RNA helicases in the transition from NMD complexes that

199 brary screen targeting the 58 human DEAD-box RNA helicases in two permissive human cancer cells (HeLa

200 We show the role of DHX9, an RNA helicase, in splicing regulation of several SMN exon

201 The nucleus-encoded chloroplast RNA helicase INCREASED SIZE EXCLUSION LIMIT2 (ISE2) is r

202 g sarcoma clinical trials and development of RNA helicase inhibition as a novel anti-neoplastic strat

203 ctor-stimulated MCF-10A cells with the eIF4A RNA helicase inhibitors, silvestrol and CR-1-31-B, block

204 However, it is unclear how most RNA helicases interact with ribosome assembly intermedia

205 DDX3X is a conserved DEAD-box RNA helicase involved in translation initiation and othe

206 les as a modulator of ATP-dependent DEAD-box RNA helicases involved in messenger (m)RNA export, trans

207 dings also indicate that targeting the eIF4A RNA helicase is a novel approach for blocking MUC1-C ove

208 p68 RNA helicase is a prototypical RNA helicase.

209 This DEAD-box RNA helicase is known to be associated with various comp

210 Prp43 and of all other spliceosomal DEAH-box RNA helicases is still elusive.

211 factor 4A (eIF4A), an ATP-dependent DEAD-box RNA helicase, is a critical component of the eIF4F compl

212 DHX15, a DEAH box containing RNA helicase, is a splicing factor required for the last

213 Here, we found that Dhh1, a DExD/H-box RNA helicase, is required for efficient translation of A

214 s the prototypical example of a DEA(D/H)-box RNA helicase, it is highly likely that this unwinding me

215 factor 4A (eIF4A), an ATP-dependent DEAD-box RNA helicase; its messenger RNA selectivity is proposed

216 folding subunit) and eIF4A (an ATP-dependent RNA helicase) leads to assembly of active eIF4F complex.

217 ionary connections between TRIM proteins and RNA helicases, linking ubiquitin and RNA biology through

218 Unlike a previously reported DEAD box RNA helicase (LOW EXPRESSION OF OSMOTICALLY RESPONSIVE G

219 The RNA helicase melanoma differentiation-associated gene-5

220 subset of mRNAs through its interaction with RNA helicase Moloney leukemia virus 10 (MOV10).

221 f RBPs, including the binding effects of the RNA helicase MOV10 on mRNA degradation, the potentially

222 Our data highlight the central role of the RNA helicase Mtl1 in regulation of the complex and provi

223 physical proximity and coupled activities of RNA helicase Mtr4 (and senataxin) with the noncoding RNA

224 These include the DEAH-box RNA helicase Mtr4 together with an RNA-binding protein (

225 subunit Rrp6 and with the exosome-associated RNA helicase Mtr4.

226 with polyadenylation and the function of the RNA helicase Mtr4p in modulating poly(A) addition.

227 tional developmental arrest phenotype of the RNA helicase mutant and identified genes involved in rib

228 al protease, the structure of the N-terminal RNA helicase (nsP2h) has not been determined.

229 RNA helicases of the DEAH/RHA family are involved in man

230 Viral RNA helicases of the NS3/NPH-II group unwind RNA duplexe

231 RNA helicases often require protein cofactors to provide

232 The RNA helicase p68 (DDX5) is an established co-activator o

233 ng: the splicing factor SRSF1 (SF2/ASF), the RNA helicase p68 (DDX5), and the heterogeneous nuclear r

234 both types of DM is caused by deficiency of RNA helicase p68.

235 DEAD box RNA helicases play central roles in RNP biogenesis.

236 DEAD/DEAH box RNA helicases play essential roles in numerous RNA metab

237 RNA helicases play fundamental roles in modulating RNA s

238 RNA helicases play various roles in ribosome biogenesis

239 The DEAD-box class of RNA helicases plays fundamental roles in formation of RN

240 quids or solid lattices, whereas a conserved RNA helicase prevents polymerization into nondynamic sol

241 sing proteomics, we found that Pgr binds the RNA helicase protein Ddx21.

242 y-terminal Sec63-2 domain, with the splicing RNA helicase Prp16p.

243 RP1, MCM2-7, PCNA, RPA1) and RNA metabolism (RNA helicases, PRP19, p54(nrb), splicing factors).

244 At1g32490 is a homolog of the yeast splicing RNA helicases Prp2 and Prp22.

245 our results suggest that the cold-inducible RNA helicase RCF1 is essential for pre-mRNA splicing and

246 Our study sheds light on the roles of the RNA helicase region in viral replication and provides in

247 Here, we show that DHX34, an RNA helicase regulating NMD initiation, directly interac

248 l NMD substrates, presenting a new model for RNA helicase regulation and target selection in the NMD

249 RNA helicases remove secondary structures that impede ri

250 are 1.6129 and 1.14 nM for DNA helicase and RNA helicase, respectively.

251 We show that the host DDX21 RNA helicase restricts influenza A virus by binding PB1

252 y pattern recognition receptors, such as the RNA helicase retinoic acid-inducible gene I (RIG-I), tha

253 he Kreb's cycle enzyme aconitase, a DEAD-box RNA helicase RhlB and the exoribonuclease polynucleotide

254 processing activities, can interact with the RNA helicase RhlB independently of RNA degradosome forma

255 eotide phosphorylase (PNPase), ATP-dependent RNA helicase (RhlE), ribonuclease E (RNase E) and ribonu

256 ination events in bacteria often require the RNA helicase Rho.

257 The cytoplasmic RNA helicase RIG-I mediates innate sensing of RNA viruse

258 ch in turn upregulates the expression of the RNA helicases RIG-I and MDA5.

259 e have shown that LACV infection induced the RNA helicase, RIG-I, and mitochondrial antiviral signali

260 ki3-Ski8 (Ski) complex containing the 3'->5' RNA helicase Ski2 binds to 80S ribosomes near the mRNA e

261 Here, we show that the DEAD box RNA helicase smut-1 functions redundantly in the mutator

262 rom the plant genus Aglaia, which target the RNA helicase subunit of eIF4F, eIF4A.

263 removal of the secondary structure of the by RNA helicases such as eIF4A.

264 ng protein (MAVS), the signaling adaptor for RNA helicases such as RIG-I, resulted in increased death

265 ere it interacts with the MOV10 RISC complex RNA helicase, suggesting a role for IRAV in the processi

266 plicing was unrelated to the activity of the RNA helicase, suggesting that the helicase does indeed p

267 ous genes encoding members of the DExD/H-box RNA helicase superfamily might also underlie development

268 tion in human cells. We found that DDX3X, an RNA helicase, suppresses the repeat-associated non-AUG t

269 h AU-rich element (RHAU) is an ATP-dependent RNA helicase that demonstrates high affinity for quadrup

270 DDX3X is a DEAD-box RNA helicase that has been implicated in multiple aspect

271 e yeast Saccharomyces cerevisiae Sen1, a DNA/RNA helicase that is essential for yeast cell viability

272 ION LIMIT2 (ISE2) is a chloroplast-localized RNA helicase that is indispensable for proper plant deve

273 UPF1 is an RNA helicase that is required for nonsense-mediated mRNA

274 Brr2 is a DExD/H-box RNA helicase that is responsible for U4/U6 unwinding, a

275 Activated PARP-1 ADP-ribosylates DDX21, an RNA helicase that localizes to nucleoli and promotes rDN

276 UPF1 is an RNA helicase that orchestrates nonsense-mediated decay a

277 DHX9/RNA helicase A (RHA) is a host RNA helicase that participates in many critical steps of

278 e deficient in MOV10L1, a germ cell-specific RNA helicase that plays a key role in limiting the propa

279 RNA helicase A (RHA) is a DExH-box RNA helicase that plays multiple roles in cellular biolo

280 ealed that ISE2 is a non-canonical Ski2-like RNA helicase that represents a separate sub-clade unique

281 The MOV10L1/Armitage RNA helicase then facilitates the translocation of ribos

282 th Nsp9 and its RdRp and recruiting cellular RNA helicase to promote the production of longer viral s

283 teract directly with the mRNA export-related RNA helicase UAP56 and the interaction was mediated by a

284 In addition to the RNA helicase UAP56 and the mRNA export factors ALY2-4 an

285 at interacts directly with the ATP-dependent RNA helicase up-frameshift 1 (UPF1) to reduce the half-l

286 ntaining mRNAs are controlled by the group I RNA helicase Upf1 and the proteins it interacts with, Up

287 ed miRNAs does not require the ATP-dependent RNA helicase UPF1 in vitro, we report here that cellular

288 A central NMD factor is the ATP-dependent RNA helicase upframeshift 1 (UPF1).

289 equently, a substrate of SMG1, ATP-dependent RNA helicase upframeshift 1, is hyperphoshorylated in a

290 Amplifier is nucleated by the DEAD box RNA helicase Vasa and contains the two Piwi proteins par

291 primary driver of the rapid evolution of the RNA helicases, while selective constraint has been a str

292 l component of the NMD machinery is UPF1, an RNA helicase whose ATPase activity is essential for NMD,

293 conserved set of proteins including UPF1, an RNA helicase whose ATPase activity is essential for NMD.

294 PRD-1 is an RNA helicase whose orthologs, DDX5 [DEAD (Asp-Glu-Ala-As

295 UPF1 is a DNA/RNA helicase with essential roles in nonsense-mediated m

296 Ded1 is a DEAD-box RNA helicase with essential roles in translation initiat

297 DDX3 is a DEAD box RNA helicase with oncogenic properties.

298 a conserved, essential regulator of DEAD-box RNA helicases, with critical roles defined in mRNA expor

299 y recently the human adenosinetriphosphatase/RNA helicase X-linked DEAD-box polypeptide 3 (DDX3X) eme

300 th the H/ACA snoRNP protein yNhp2/hNHP2, the RNA helicase yRok1/hROK1(DDX52), the ribosome biogenesis