ライフサイエンスコーパス: RNA polymerase

1 A functionality and its interaction with the RNA polymerase.

2 erase II and subunits RpoB-RpoC of bacterial RNA polymerase.

3 n of transcripts as soon as they emerge from RNA polymerase.

4 essential gene encoding the beta-subunit of RNA polymerase.

5 cells using a cytidine deaminase fused to T7 RNA polymerase.

6 hances contacts between the DNA backbone and RNA polymerase.

7 ound middle promoters and recruits the phage RNA polymerase.

8 nt harboring a mutation in the RNA-dependent RNA polymerase.

9 s characterized by low expression and poised RNA-polymerase.

10 ast majority of the genome is transcribed by RNA polymerases.

11 izes with complementary DNA templates behind RNA polymerases.

12 when misincorporated by viral RNA-dependent RNA polymerases.

13 re dependent on RNA Pol IV and RNA-DEPENDENT RNA POLYMERASE 2 (RDR2) and establish DNA methylation at

14 acetylation, and prevents the positioning of RNA Polymerase 2 at promoters impeding transcription ini

15 kout of NICI leads to reduced recruitment of RNA polymerase 2 to the SLC2A3 promoter.

16 ing are instead processed into RNA-dependent RNA polymerase 6-dependent small RNAs, resulting in thei

17 genes in a manner dependent on RNA-dependent RNA polymerase activity and on DRH-1.

18 ment of specific metal cofactors for maximal RNA polymerase activity.

19 A combination of highly processive RNA polymerases, allosteric protein transcription factor

20 and-mouth disease virus (FMDV) RNA-dependent RNA polymerase allows FMDV to exhibit high genetic diver

21 Translocation of DNA and RNA polymerases along their duplex substrates results in

22 ing-like domain containing the RNA-dependent RNA polymerase and an appendage of globular domains cont

23 zation of AceR to enable interaction between RNA polymerase and promoter DNA were also observed follo

24 Cells encode several RNA polymerase and R-loop clearance mechanisms to limit

25 6S RNA binds to RNA polymerase and regulates gene expression, contributi

26 vealed how RNA slips on template DNA and how RNA polymerase and template DNA determine length of reit

27 sed that this is due to physical coupling of RNA polymerase and the lead ribosome on nascent mRNA, an

28 ealed RpoD-dependent promoter selectivity by RNA polymerase and the requirement of specific metal cof

29 nding of the functional relationship between RNA polymerase and the ribosome as well as the basis of

30 ll, both kinetic discrepancy between DNA and RNA polymerases and cellular concentration discrepancy b

31 airs that are compatible with native DNA and RNA polymerases and the ribosome, we have expanded the g

32 Recent biophysical studies of RNA polymerases and their inhibition, as well as transcr

33 enomic RNA, nucleoprotein, the RNA-dependent RNA polymerase, and a polymerase cofactor, the phosphopr

34 papain-like protease (PLpro), RNA-dependent RNA polymerase, and spike (S) protein.

35 heories of labour division between the major RNA polymerases, and identify nucleolar Pol II as a majo

36 All RNAs are produced by a phage-type RNA polymerase as 3' extended precursors, which undergo

37 We describe the well-known interactions with RNA polymerase as well as a broader range of cellular ta

38 Both intra- and interchromosomal RNA polymerase-associated contacts involve multiple gene

39 Further analysis and comparison with other RNA polymerases at different stages suggest the structur

40 lead to the arrest of transcription through RNA polymerase backtracking, which interferes with repli

41 The RNA polymerase-binding protein DksA, together with the a

42 esponsive riboswitches and the orthogonal T7 RNA polymerase, biochemical reactions needed for in vivo

43 e the rate of transcription by DNA-dependent RNA polymerases, but the influence of DNA sequence on tr

44 While PolD has an ancestral RNA polymerase catalytic core, its active site has evolv

45 as SARS-CoV-2 infection, determined by viral RNA polymerase chain reaction testing.

46 also known as 2019-nCoV) RdRp (RNA-dependent RNA polymerase) coding sequence, achieving a detection l

47 that gp14, termed here as Drc (ssDNA-binding RNA Polymerase Cofactor), preferentially binds single-st

48 ective, Drc interacts with the phage-encoded RNA Polymerase complex (RNAPII), implying a functional r

49 tations reduce protein affinities within the RNA polymerase complex, subsequently reducing nucleic ac

50 elical ribonucleocapsid and an RNA-dependent RNA polymerase composed of a catalytic subunit, the L pr

51 The respiratory syncytial virus (RSV) RNA polymerase, constituted of a 250 kDa large (L) prote

52 d MvaU leads to a striking redistribution of RNA polymerase containing sigma(70) to genomic regions v

53 nd UPS-dependent degradation of rice NUCLEAR RNA POLYMERASE D1a (OsNRPD1a), one of two orthologs of t

54 g that the total output of the ribosomes and RNA polymerases described by data are not sufficient for

55 Similarly, RNA polymerases display much higher K(m) values than DNA

56 P-OD associates with the RNA-dependent RNA polymerase domain of L and protrudes away from it, w

57 e of a functional E. coli trxA allele and T7 RNA polymerase-driven expression but is independent of t

58 The error-prone nature of RNA-dependent RNA polymerases drives the diversity of RNA virus popula

59 the X-ray crystal structure of the bacterial RNA polymerase engaged in reiterative transcription from

60 d and replicated by the viral heterotrimeric RNA polymerase (FluPol) in the context of viral ribonucl

61 fluenza viruses encode a viral RNA-dependent RNA polymerase (FluPol), which is responsible for transc

62 licated and transcribed by the RNA-dependent RNA polymerase holoenzyme (subunits nsp7/nsp8(2)/nsp12)

63 transcription assay using the B. burgdorferi RNA polymerase holoenzyme.

64 t regions, preventing them from sequestering RNA polymerase; however, it is not known whether MvaT an

65 cription elongation properties of eukaryotic RNA polymerase I (Pol I) from Saccharomyces cerevisiae h

66 RNA polymerase I (Pol I) is a highly efficient enzyme sp

67 Ribosomal RNA (rRNA) transcription by RNA polymerase I (Pol I) is the first key step of riboso

68 revisiae that plays dual roles in activating RNA polymerase I (Pol I) transcription and repression of

69 interferes with rDNA DSB repair and impacts RNA polymerase I activity and cell viability.

70 sage as a specific chemical genetic probe of RNA polymerase I function is challenging to interpret.

71 CX-5461 was developed as a selective RNA polymerase I inhibitor, but recent evidence suggests

72 CSB and CSA also increase RNA Polymerase I loading to the coding region of the rDN

73 ocalizes to the nucleoli and associates with RNA polymerase I transcribed ribosomal RNA gene, Rn45s.

74 ate CX-5461, the first-in-class inhibitor of RNA polymerase I transcription of ribosomal RNA genes (r

75 Existing models suggest that RNA polymerases I and III (Pol I and Pol III) are the on

76 RNA polymerase II (Pol II) and its general transcription

77 nd found that H2A.Z eviction is dependent on RNA Polymerase II (Pol II) and the Kin28/Cdk7 kinase, wh

78 The journey of RNA polymerase II (Pol II) as it transcribes a gene is a

79 gene expression or transcription factor and RNA polymerase II (Pol II) association with viral DNA pr

80 tacc-seq), we investigated the landscapes of RNA polymerase II (Pol II) binding in mouse embryos.

81 ylates the carboxyl-terminal domain (CTD) of RNA polymerase II (pol II) but its roles in transcriptio

82 The RNA polymerase II (Pol II) core promoter is the strategi

83 The former is regulated by RNA polymerase II (pol II) de novo recruitment or loss;

84 inal domain (CTD) of the RPB1 subunit of the RNA polymerase II (Pol II) has been revived in recent ye

85 mere regions retain transcriptionally active RNA polymerase II (Pol II) in mitosis.

86 Here we show, however, that RNA polymerase II (Pol II) inside human nucleoli operate

87 nscription, and promoter-proximal pausing of RNA polymerase II (Pol II) is a critical step in transcr

88 Transcription by RNA polymerase II (Pol II) is carried out by an elongati

89 Condensates containing RNA polymerase II (Pol II) materialize at sites of activ

90 t its disruption manifests as a reduction of RNA polymerase II (Pol II) occupancy downstream of trans

91 The phenomenon of RNA polymerase II (Pol II) pausing at transcription star

92 depends on many factors that together direct RNA polymerase II (pol II) through the different stages

93 nd that prp5 alleles decrease recruitment of RNA polymerase II (Pol II) to an intron-containing gene,

94 RNA polymerase II (Pol II) transcribes all protein-codin

95 scription factor that stimulates the rate of RNA polymerase II (Pol II) transcription elongation in v

96 to a lesser extent, exon-targeted ASOs cause RNA polymerase II (Pol II) transcription termination in

97 ribed from > 15,000 discrete genomic loci by RNA polymerase II (Pol II), resulting in 28 nt short-cap

98 on, resulting in degradation of the residual RNA polymerase II (Pol II)-associated RNA by XRN2 and di

99 1 (HSV-1) genes are transcribed by cellular RNA polymerase II (Pol II).

100 ls from DNA-binding transcription factors to RNA polymerase II (Pol II).

101 binding and recruitment of coactivators and RNA polymerase II (Pol II).

102 RNA polymerase II (RNA Pol II) contains a disordered C-t

103 Precise control of the RNA polymerase II (RNA Pol II) cycle, including pausing

104 RNA polymerase II (RNA Pol II) is generally paused at pr

105 ore increases Mediator-driven recruitment of RNA polymerase II (RNA Pol II) to promoters and enhancer

106 sphorylation within the C-terminal domain of RNA polymerase II (RNAP II) and in the recruitment of th

107 Here, we report that ATXN3 associates with RNA polymerase II (RNAP II) and the classical nonhomolog

108 le 1-beta-D-ribofuranoside (DRB), to measure RNA polymerase II (RNAPII) elongation rates in vivo, a t

109 nd phosphorylating the C-terminal domain for RNA polymerase II (RNAPII) for activation.

110 ption of transcription termination (DoTT) of RNA polymerase II (RNAPII) in host genes.

111 Transcription by RNA polymerase II (RNAPII) is a dynamic process with fre

112 elongation factors associate with elongating RNA polymerase II (RNAPII) to control the efficiency of

113 In eukaryotes, RNA polymerase II (RNApII) transcribes messenger RNA fro

114 RNA polymerase II (RNAPII) transcription is governed by

115 e 2 (Ser2) of the carboxy-terminal domain of RNA polymerase II (RNAPII), which is initiated when RNAP

116 Elongin is an RNA polymerase II (RNAPII)-associated factor that has be

117 recruited to DNA damage sites in a PARP- and RNA polymerase II (RNAPII)-dependent manner.

118 the fate of many nascent RNAs transcribed by RNA polymerase II (RNAPII).

119 osphorylating the C-terminal domain (CTD) of RNA polymerase II (RNAPII).

120 ion, and none of them affected host cellular RNA polymerase II activities.

121 RNA methylation machinery, the NuRD complex, RNA polymerase II and factors involved in the regulation

122 mentalization of the gene-control machinery, RNA polymerase II and its cofactors, within biomolecular

123 ly the method to subunits Rpb1-Rpb2 of yeast RNA polymerase II and subunits RpoB-RpoC of bacterial RN

124 Ubp15 interacts with both RNA polymerase II and the nuclear pore complex, and its

125 AM1 promoter resulted in graded RelA/p65 and RNA polymerase II binding that gave rise to a distributi

126 Rapid reduction of RNA polymerase II binding was accompanied by reduced bin

127 anscription factor II H (TFIIH) it activates RNA polymerase II by hyperphosphorylation of its C-termi

128 Set1/COMPASS associates with the RNA polymerase II C-terminal domain (CTD) to establish p

129 The RNA polymerase II carboxyl terminal domain (RNAPII CTD)

130 ologous end-joining pathway factor, that the RNA polymerase II component ELOF1 modulates the response

131 s influenced by the Thr4 phospho-site in the RNA polymerase II CTD and the 3' processing/termination

132 complex as a terminator of promoter-proximal RNA polymerase II during piRNA biogenesis.

133 NA degradation and larger Ser2p CTD-modified RNA polymerase II foci.

134 In animals, RNA polymerase II initiates transcription bidirectionall

135 etylated regions are formed after inhibiting RNA polymerase II initiation.

136 RNA polymerase II interacts with various other complexes

137 The molecular process of transcription by RNA Polymerase II is highly conserved among eukaryotes (

138 Gene transcription by RNA polymerase II is regulated by activator proteins tha

139 hment at HIF target gene promoters increased RNA polymerase II loading through p300.

140 demonstrate that PTEN modulates genome-wide RNA Polymerase II occupancy in cells undergoing glucose

141 f NF-kB, P-TEFb, and serine 2 phosphorylated RNA Polymerase II on the HEXIM1 gene.

142 we report that widespread promoter-proximal RNA polymerase II pausing in resting macrophages is mark

143 We found that integrator and NELF, an RNA polymerase II pausing protein, were associated with

144 ve historically focused on events leading to RNA polymerase II recruitment and transcription initiati

145 duction of TNF and LTA mRNA synthesis and of RNA polymerase II recruitment to their promoters.

146 ogy was found across the range of eukaryotic RNA polymerase II subunits and their associated basal tr

147 5 condensates, which in turn further recruit RNA polymerase II to drive transcriptional output.

148 14 (H3K14ac) facilitates the processivity of RNA polymerase II to maintain the high expression of key

149 d link the SnRK2.6-mediated ABA signaling to RNA polymerase II to promote immediate transcriptional r

150 robably through promoting the recruitment of RNA polymerase II to their promoters.

151 that TOE1 promotes maturation of all regular RNA polymerase II transcribed snRNAs of the major and mi

152 and Drosophila cells, splicing occurs after RNA polymerase II transcribes several kilobases of pre-m

153 xpressed from an intron that is generated by RNA polymerase II transcribing the circular viral genome

154 Compared to other stages in the RNA polymerase II transcription cycle, the role of chrom

155 e specifically associated with initiation of RNA Polymerase II transcription of highly expressed gene

156 TBPL2 (TBP2 or TRF3), which is essential for RNA polymerase II transcription.

157 is provided by physical interaction with the RNA polymerase II transcriptional machinery (chromatin r

158 NCBP2), associates with the nascent 5'cap of RNA polymerase II transcripts and impacts RNA fate decis

159 ates distinct isoforms of mRNAs and/or other RNA polymerase II transcripts with different 3'UTR lengt

160 ple-arise from Bre1 and Rad6 travelling with RNA polymerase II(2), the mechanism of H2B ubiquitinatio

161 co-binding of the tumor suppressor BRCA1 and RNA polymerase II, a well-known transcriptional pair in

162 anscriptional machinery, including NCOA3 and RNA polymerase II, but does not alter AR binding itself.

163 eport that zinc finger protein ZPR1 binds to RNA polymerase II, interacts in vivo with SMN locus and

164 PAF1, a RNA polymerase II-associated factor 1 complex (PAF1C) co

165 F1 in CSC maintenance was independent of its RNA polymerase II-associated factor 1 complex component

166 Alpha-satellite expression occurs through RNA polymerase II-dependent transcription, but does not

167 st cancer cells by increasing recruitment of RNA polymerase II.

168 1 (DCL1) and Hyponastic Leaves 1 (HYL1) with RNA Polymerase II.

169 ectly stimulates transcription elongation by RNA polymerase II.

170 and operates by recruiting and/or initiating RNA Polymerase II.

171 s interactions with the C-terminal domain of RNA polymerase II.

172 y modulating the association of Mediator and RNA polymerase II.

173 A repair, mRNA processing, and regulation of RNA polymerase II.

174 RNP interacts with transcriptionally engaged RNA polymerase II.

175 n factors and transcriptional machinery like RNA Polymerase II.

176 f serine-2 in the C-terminal domain (CTD) of RNA-polymerase II (Pol II), and reduces the expression o

177 Thus, it is perplexing how RNA-polymerase II (RNAPII) can successfully transcribe t

178 rucial to the regulation of transcription by RNA-polymerase II, via its interaction with the positive

179 Maf1 is a conserved inhibitor of RNA polymerase III (Pol III) that influences phenotypes

180 rt interspersed nuclear elements (SINEs) are RNA polymerase III (RNAPIII)-transcribed, retrotransposa

181 ing a central role of Alu elements (AEs) and RNA polymerase III transcription factor C (TFIIIC) in st

182 BRF1 is a rate-limiting factor for RNA Polymerase III-mediated transcription and is elevate

183 ld normally remodel the C-terminal domain of RNA polymerase in anticipation of termination.

184 rtly mediated by paradoxical upregulation of RNA polymerase in response to rifampicin.

185 is a non-canonical form of RNA synthesis by RNA polymerase in which a ribonucleotide specified by a

186 cription initiation factors of mitochondrial RNA polymerases in Saccharomyces cerevisiae and humans,

187 h the efficiency with which Escherichia coli RNA polymerase incorporates dinucleoside polyphosphates

188 lls grown in the presence and absence of the RNA polymerase inhibitor rifampicin, we identify hundred

189 However, it is not clear how RNA polymerase initially recognizes such sequences.

190 RNA polymerases initiate transcription at DNA sequences

191 E. coli RNA polymerase initiates transcription more efficiently

192 pathogens and commensals, and the bacterial RNA polymerase is a proven target for antibiotics.

193 However, it is unclear how RNA polymerase is engaged in initiating ZGA in mammals.

194 rate that while binding and initiation of T7 RNA polymerase is unchanged, the efficiency of elongatio

195 The enzyme responsible for transcription, RNA polymerase, is conserved in general architecture and

196 B. burgdorferi 6S RNA (Bb6S RNA) binds to RNA polymerase, is expressed independent of growth phase

197 dopsis (Arabidopsis thaliana), DNA-dependent RNA polymerase IV (Pol IV) is required for the formation

198 ogs of the largest subunit of plant-specific RNA polymerase IV (Pol IV), which is required for RNA-di

199 to IBs, including VP35, VP24, VP30, and the RNA polymerase L.

200 The RNA-dependent-RNA polymerase (L) gene revealed phylogenetic relationsh

201 After detachment of NusG and clamp opening, RNA polymerase loses its grip on the RNA:DNA hybrid and

202 A de novo, all organisms require primase, an RNA polymerase making short RNA primers which are then e

203 arget genes, alpha-tubulin and mitochondrial RNA polymerase (mtpol), were significantly increased whe

204 Mitochondrial RNA polymerase (mtRNAP) is crucial in cellular energy pr

205 These RNA polymerase mutations cause large-scale transcription

206 The hepatitis C virus RNA-dependent RNA polymerase NS5B is responsible for the replication o

207 nation of RNA synthesis by the RNA-dependent RNA polymerase of some viruses.

208 showed positive results on an RNA-dependent RNA polymerase or open reading frame 1b gene assay.

209 is focused on either the viral RNA-dependent RNA polymerase or the main viral protease, 3CL(pro) 3CL(

210 f ssDNA produced by transcriptionally active RNA polymerases or other processes in situ using as few

211 ad, the translating ribosome actively pushes RNA polymerase out of the backtracked state, thereby rea

212 and provides more accurate quantification of RNA polymerase pause indices.

213 transcriptional machinery, and facilitating RNA polymerase pause-release to regulate gene expression

214 T, stimulates transcriptional elongation by RNA polymerase (Pol) II and regulates cell growth and di

215 f trimethyl H3K4 and phosphorylated forms of RNA polymerase (Pol) II at the promoter and gene body.

216 sphorylation in RPB1, the largest subunit of RNA polymerase (pol) II.

217 l growth control as the central regulator of RNA polymerase (Pol) III activity.

218 RNA polymerase (Pol) III has a noncanonical role of vira

219 In eukaryotes, RNA Polymerase (Pol) III is specialized for the transcri

220 The negative regulator of RNA polymerase (pol) III mafr-1 has been shown to affect

221 ucleotides stemming from the deregulation of RNA polymerase (pol) III transcription.

222 express at least three nuclear DNA-dependent RNA polymerases (Pols) responsible for synthesizing all

223 dicted, including unusual ones such as giant RNA polymerase polyproteins.

224 Silencing expression of RNA-directed RNA polymerases RdR1 and RdR2 (but not RdR3) and Dicer-l

225 The structure reveals that the RNA dependent RNA polymerase (RdRp) and capping (Cap) domains of L int

226 in the thumb subdomain of the RNA-dependent RNA polymerase (RdRp) and the methyltransferase (MTase)

227 the NS5 methyltransferase and RNA-dependent RNA polymerase (RdRP) domains form a conserved interdoma

228 The viral RNA-dependent RNA polymerase (RdRp) is a promising therapeutic target.

229 RDV targets the viral RNA-dependent RNA polymerase (RdRp) of severe acute respiratory syndro

230 mice expressing a picornavirus RNA-dependent RNA polymerase (RdRP) outside the viral context (RdRP mi

231 The viral RNA-dependent RNA polymerase (RdRP) resides within an approximately 25

232 Dengue virus (DENV) NS5 RNA-dependent RNA polymerase (RdRp), an important drug target, synthes

233 mes that typically encode only RNA-dependent RNA polymerase (RdRP), capping enzyme and capsid protein

234 e and the L protein, which has RNA-dependent RNA polymerase (RdRp), GDP polyribonucleotidyltransferas

235 tains motifs representative of RNA-dependent RNA polymerase (RdRp), whereas the dsRNA2 ORF sequence s

236 ARS-CoV-2 depends on the viral RNA-dependent RNA polymerase (RdRp), which is the likely target of the

237 s low levels of a picornaviral RNA-dependent RNA polymerase (RdRP), which synthesizes double-stranded

238 L gene-which encodes the viral RNA-dependent RNA polymerase (RdRp).

239 hich is performed by the viral RNA dependent RNA polymerase (RdRp).

240 tease (3CL(pro)) and the nsp12 RNA-dependent RNA-polymerase (RdRp) are the best characterized SARS-Co

241 Picornaviral RNA-dependent RNA polymerases (RdRPs) have low replication fidelity th

242 delity SARS-CoV and SARS-CoV-2 RNA-dependent RNA polymerases (RdRps), serving as an immediate polymer

243 nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps).

244 lear export of messenger RNAs resulting from RNA polymerase readthrough.

245 Further experiments showed that RNA polymerase relieves this autoinhibition by interacti

246 atically and accurately measure the apparent RNA-polymerase resource budget will enable researchers t

247 virus replication and cellular RNA-dependent RNA polymerases responsible for gene silencing amplifica

248 in virus-derived siRNAs: viral RNA-dependent RNA polymerases responsible for virus replication and ce

249 to have descended would have depended on an RNA polymerase ribozyme to copy functional RNA molecules

250 Here the class I RNA polymerase ribozyme was evolved in vitro for the abi

251 onditions and components on bacteriophage T7 RNA polymerase (RNAP) activity using a common quantitati

252 is six-subunit (2alphabetabeta'omegaepsilon) RNA Polymerase (RNAP) core enzyme, sigma(A), a promoter

253 unveils that RNA transcript release precedes RNA polymerase (RNAP) dissociation from the DNA template

254 Pausing by RNA polymerase (RNAP) during transcription elongation, i

255 the additional initiation factor Bdp1 in the RNA polymerase (RNAP) III system, however, remained elus

256 S) as a mechanism for organizing clusters of RNA polymerase (RNAP) in Escherichia coli Using fluoresc

257 ces have enabled single-cell measurements of RNA polymerase (RNAP) molecules engaged in the process o

258 Transcription is punctuated by RNA polymerase (RNAP) pausing.

259 ermination factor playing essential roles in RNA polymerase (RNAP) recycling, gene regulation, and ge

260 flagella-specific sigma factor that targets RNA polymerase (RNAP) to control the expression of flage

261 However, whether and how it modifies RNA polymerase (RNAP) to initiate transcription remains

262 in vitro transcription system with purified RNA polymerase (RNAP) to investigate rRNA synthesis in t

263 The RNA polymerase (RNAP) trigger loop (TL) is a mobile stru

264 ly associate and kinetically coordinate with RNA polymerase (RNAP)(3-11), forming a signal-integratio

265 the beta and beta' subunits of multi-subunit RNA polymerase (RNAP), a high-resolution phylogenetic ma

266 ise transcription and block RNA synthesis by RNA polymerase (RNAP), leading to subsequent recruitment

267 hat bind to the secondary channel of E. coli RNA polymerase (RNAP), such as GreA, GreB or DksA.

268 important DNA repair mechanism that removes RNA polymerase (RNAP)-stalling DNA damage from the trans

269 e coupled processes in which the movement of RNA polymerase (RNAP)-synthesizing messenger RNA (mRNA)

270 on of RNA hydrolysis by the active centre of RNA polymerase (RNAP).

271 d H(D), the templates I'/I and J'/J, and the RNA polymerase (RNAp)/NTPs machinery.

272 s(-1) [comparable to the speed of bacterial RNA polymerase (RNAP)].

273 Cellular RNA polymerases (RNAPs) can become trapped on DNA or RNA

274 Site-specific arrest of RNA polymerases (RNAPs) is fundamental to several techno

275 RNA polymerases (RNAPs) transcribe genes through a cycle

276 the catalytic site in cellular multisubunit RNA polymerases (RNAPs)(5).

277 l other DNA polymerase families but found in RNA polymerases (RNAPs).

278 r predicted virion proteins, including three RNA polymerase subunits.

279 NS5B is the RNA-dependent RNA polymerase that catalyzes the replication of the hep

280 ipient hairpin, the linker-sequence, and the RNA polymerase that transcribes the hairpins.

281 yotes, gene expression is performed by three RNA polymerases that are targeted to promoters by molecu

282 ory proteins and sigma factors interact with RNA polymerase to direct transcription.

283 The failure of RNA polymerase to read through the mutation also reduces

284 ic counterparts by utilizing multifunctional RNA polymerases to replicate entire viral genomes and tr

285 d the contribution of cellular RNA-dependent RNA polymerases to the generation of mutations in virus-

286 dy various motors such as helicases, DNA and RNA polymerases, topoisomerases, nucleosome remodelers,

287 In this system, called Zombie, phage RNA polymerases transcribe engineered barcodes in fixed

288 RNA polymerase transcribes certain genomic loci with hig

289 RNA polymerase transcription complexes co-directionally

290 ng the activities of essential, multisubunit RNA polymerase transcription elongation complexes (TECs)

291 contacts NusA, NusG, and multiple regions of RNA polymerase, trapping and locally unwinding proximal

292 RNA polymerase variants that are thought to increase or

293 The viral RNA-dependent RNA polymerase (vRdRp) of MuV consists of the large prot

294 African swine fever virus (ASFV) and the T7 RNA polymerase were expressed.

295 The virus encodes an RNA-dependent RNA polymerase, which replicates and transcribes the vRN

296 e gene silencing by recruiting RNA-dependent RNA polymerases, which use pUG-tailed RNAs (pUG RNAs) as

297 and bioaerosols that produce allergies have RNA polymerase with a propensity to generate RNA gaps, t

298 complex formation by blocking interaction of RNA polymerase with the promoter -10 element, while not

299 tic parameters of cellular and viral DNA and RNA polymerases with respect to cellular levels of their

300 n deflection of distal upstream DNA over the RNA polymerase zinc-binding domain, NusA rotates underne