ライフサイエンスコーパス: RNA transcript

1 coordinate strand annealing and the nascent RNA transcript.

2 the highly controlled release of the nascent RNA transcript.

3 emplate is repetitively added to the nascent RNA transcript.

4 II), synthesizing a complementary messenger RNA transcript.

5 gested by a 10.4-fold reduction in L-protein RNA transcript.

6 f the beta subunit, blocking the path of the RNA transcript.

7 ds to the 3'-untranslated region of the pgdA RNA transcript.

8 predicted to alter the splicing of the DOK7 RNA transcript.

9 gene within sequences of BGL3, an intergenic RNA transcript.

10 aplotype and located in the 5' region of the RNA transcript.

11 elements at virtually any location within an RNA transcript.

12 on when a DNA duplex is invaded by a nascent RNA transcript.

13 change on specific nucleotide sequence in an RNA transcript.

14 n complex (CAP-TAC) with and without de novo RNA transcript.

15 pendent messenger RNA levels and splicing of RNA transcripts.

16 RBPs), which coordinate regulatory events on RNA transcripts.

17 promoter controlling the expression of novel RNA transcripts.

18 agments do not lead to observable changes in RNA transcripts.

19 ions to produce genome- and subgenome-length RNA transcripts.

20 ons as single units from precursor messenger RNA transcripts.

21 identification of protein-coding regions in RNA transcripts.

22 ulation of both spliced and nonspliced viral RNA transcripts.

23 se-pairing of associated siRNAs with nascent RNA transcripts.

24 late for RNA polymerase V-mediated noncoding RNA transcripts.

25 TAP in the nuclear export of gammaretroviral RNA transcripts.

26 hput sequencing of DNA and its corresponding RNA transcripts.

27 chemistry for improved spatial detection of RNA transcripts.

28 events, gene fusions and other variations in RNA transcripts.

29 o acids increase hepatic cyclin D1 messenger RNA transcripts.

30 le, leading to the release of short abortive RNA transcripts.

31 NA molecules that are complementary to known RNA transcripts.

32 ross many sites in granule proteins and long RNA transcripts.

33 hundreds or even thousands of protein-coding RNA transcripts.

34 tially reduces the levels of Pol V-dependent RNA transcripts.

35 have revealed a large number of un-annotated RNA transcripts.

36 ion of expressed genes and reconstruction of RNA transcripts.

37 hancers, MyoD1-binding events, and noncoding RNA transcripts.

38 using a series of full-length prequantified RNA transcripts.

39 oteins to repress the stability of messenger RNA transcripts.

40 sms that undergo C-to-U editing of organelle RNA transcripts.

41 tion of both expressed coding and non-coding RNA transcripts.

42 ons can alter the function and metabolism of RNA transcripts.

43 gulatory regions proximal to long non-coding RNA transcripts.

44 anism's transcriptome, the sum of all of its RNA transcripts.

45 lls, SUV39H1 associates with alpha-satellite RNA transcripts.

46 viruses and other pharmacologically relevant RNA transcripts.

47 esholds in deep-sequencing datasets of short RNA transcripts.

48 aB signaling, and heat shock protein pathway RNA transcripts.

49 n of transposable element (TE)-derived small RNA transcripts.

50 become the assay of choice for interrogating RNA transcript abundance and diversity.

51 Messenger RNA transcript abundance did not reliably predict protei

52 R) to measure relative fecal IL-8 and CXCL-5 RNA transcript abundances, and quantitative PCR to enume

53 These RNA transcripts act as competing endogenous RNAs (ceRNAs

54 s systematic nucleotide insertion throughout RNA transcripts, altering previous views that RNA editin

55 Due to the large sizes and abundance of the RNA transcripts, an efficient and accurate RNA structure

56 d allow alteration and imaging of endogenous RNA transcripts analogous to CRISPR/Cas-based genomic to

57 RNA transcript analyses of erythroid cells from controls

58 d from Salmonella 5'-leader of the ribosomal RNA transcript and has a 'stem' structure-containing pre

59 on by promoting both the dissociation of the RNA transcript and the closing of the transcription bubb

60 that persistent hybrids between the nascent RNA transcript and the template DNA strand at CTG.CAG tr

61 in the length and sequence at the 5' end of RNA transcripts and can be important for gene regulation

62 l of HIV, and with levels of HLA-C messenger RNA transcripts and cell-surface expression, but the mec

63 lternative splicing expands the diversity of RNA transcripts and plays an important role in tissue-sp

64 g technologies facilitate discovery of novel RNA transcripts and protein isoforms, applications rangi

65 Interestingly, messenger RNA transcripts and proteins involved in chlorophyll bre

66 ) for the simultaneous detection of specific RNA transcripts and proteins, greatly enhancing the spat

67 he absence of viral early and late messenger RNA transcripts and proteins.

68 lymphocytes triggers the return of XIST/Xist RNA transcripts and some chromatin marks (H3K27me3, ubiq

69 hanced the cytoplasmic accumulation of viral RNA transcripts and the expression of viral proteins wit

70 dertake an unbiased, total genome screen for RNA transcripts and their protein products that affect a

71 eotide, catalyze its addition to the growing RNA transcript, and move stepwise along the DNA until a

72 ly 16,000) barcoded sequences, production of RNA transcripts, and analysis of transcript ends and tra

73 smic transport of both spliced and unspliced RNA transcripts, and RNA export mechanisms of gammaretro

74 sequencing (NGS) methodologies by targeting RNA transcripts, and therefore detecting only replicatin

75 By unveiling a new class of viral lytic RNA transcripts antisense to latent EBNAs, we provide a

76 RNA transcripts are bound and regulated by RNA-binding p

77 ctor family 2 (TFF2) protein, TFF2 messenger RNA transcripts are concentrated in cells above the neck

78 Probes for RNA transcripts are designed to bind single transcripts.

79 ficiency with which individual pre-messenger RNA transcripts are productively processed across differ

80 RNA transcripts are subject to posttranscriptional gene

81 y binding both to loop structures within the RNA transcript as well as to eIF4AI.

82 We have termed such RNA transcripts as competing endogenous RNAs (ceRNAs).

83 the yeast scavenger decapping enzyme decaps RNA transcripts as long as 1400 nucleotides.

84 with this assay and enables the detection of RNA transcripts at rates comparable to workflows not inc

85 this suggests that the retention of nascent RNA transcripts at their site of expression represents a

86 eins, where sequence-specific binding to two RNA transcripts, ATPH: and PSAJ, HAS BEEN DEMONSTRATED T

87 assessed the effectiveness of a whole-blood RNA transcript-based model as a prognostic biomarker in

88 repressed by a conserved noncoding antisense RNA transcript, BDNF-AS.

89 re not dormant but were generating unspliced RNA transcripts before treatment was interrupted.

90 ermidis (S. epidermidis) Csm (SepCsm) cleave RNA transcripts, but not ssDNA, at the transcription bub

91 as a standalone RNase that degrades invader RNA transcripts, but the mechanism linking invader sensi

92 tribution of N(6)-methyladenosine (m(6)A) in RNA transcripts by analyzing different subcellular fract

93 Massive parallel sequencing of RNA transcripts by next-generation technology (RNA-Seq)

94 by RNA polymerases in vitro or in vivo, the RNA transcript can thread back onto the template DNA str

95 Here, we demonstrate that protein-coding RNA transcripts can crosstalk by competing for common mi

96 e transcription and the technical failure of RNA transcript capture, often render traditional dimensi

97 ced tethering of CG9754 to nascent messenger RNA transcripts causes cotranscriptional silencing of th

98 TRBO-mediated expression of an RNA transcript consisting of an sgRNA adjoining a GFP pr

99 ccessfully identified thousands of mammalian RNA transcripts containing the modification, it is extre

100 Transcript slippage occurs when an RNA transcript contains a repetitive sequence that allow

101 Full-length RNA transcripts could in principle complete annotations

102 wer of high-throughput sequencing to measure RNA transcript counts at an unprecedented accuracy.

103 Analysis of RNA transcripts detected fusion of the HPV/Myc genes, ar

104 eq) to simultaneously probe all intermediate RNA transcripts during transcription by stalling elongat

105 t ( approximately 160-nucleotide) non-coding RNA transcript employed by adenoviruses to subvert the i

106 Specifically, abundance of RNA transcripts encoded by the DUX4 locus correlated to

107 of tandem sequences present in the 5' UTR of RNA transcripts encoding several tryptophan metabolism g

108 nd remarkably high levels of retrotransposon RNA transcripts, especially for some human endogenous re

109 characterization of previously un-annotated RNA transcripts expressed by the spirochete during murin

110 The HIV-RNA transcripts expressed from these defective proviruse

111 RNA-seq, wherein RNA transcripts expressed in a sample are sequenced and

112 MicroRNAs (miRNAs) are small noncoding RNA transcripts expressed throughout the brain that can

113 analysis was carried out on the IgA and IgG RNA transcripts expressing IGHV3 genes in all parotid bi

114 ric (FDM) identifies regions of differential RNA transcript expression between pairs of splice graphs

115 ity: nucleotide selection and incorporation, RNA transcript extension, and proofreading.

116 Because countless RNA transcripts feature single-stranded-dsRNA junctions

117 actively transcribed, as measured by primary RNA transcript FISH.

118 size that oxidative modification of specific RNA transcripts following formaldehyde exposure denotes

119 using an RNA transcript or a DNA copy of the RNA transcript for DSB repair, respectively, and a new m

120 is of PH via the direct binding to messenger RNA transcripts for degradation or inhibition of transla

121 h, which correlated with an upregulation of RNA transcripts for ecm and a decrease in the levels of

122 s that flank the 16S region of the ribosomal RNA transcript, forming a complex with RNA polymerase th

123 identified regulatory mechanisms in which an RNA transcript forms a DNA duplex.RNA triple helix with

124 alternative splicing, result in two or more RNA transcripts from a DNA template.

125 ocess that leads to the creation of multiple RNA transcripts from a single gene.

126 20 also results in accumulation of noncoding RNA transcripts from centromeric cores, a feature common

127 splicing in Drosophila, we sequenced nascent RNA transcripts from Drosophila S2 cells as well as from

128 y(A) truncation cassette inserted to prevent RNA transcripts from elongation through KvDMR1.

129 The processing of RNA transcripts from mammalian genes occurs in proximity

130 oblasts with non-replicating, non-translated RNA transcripts from RNA viral genomes with differing de

131 By analyzing RNA transcripts from single-nucleus RNA datasets, we ide

132 old effect on the affinity of HuR binding to RNA transcripts from tens of bases away.

133 -phage DNA (10(5)-10(7) starting copies) and RNA transcripts from the GAPDH housekeeping gene (5.45 n

134 uced by alternative splicing of long primary RNA transcripts from the Ig heavy chain (Igh) locus and

135 with in vitro-transcribed full-length capped RNA transcripts from the infectious clones of each singl

136 RNA transcripts from this cDNA and the viruses encoded b

137 nd demonstrated simultaneous measurements of RNA transcripts from ~10,000 genes in individual cells w

138 After 14 days, 16S ribosomal RNA transcripts/genome declined 96%, indicating slow gro

139 Although these novel usHIV-RNA transcripts had exon structures that were different

140 generation sequencing, the ability to purify RNA transcripts has become a critical issue.

141 d, particularly when hybridized to a nascent RNA transcript, has been an enigma.

142 small RNAs target and regulate complementary RNA transcripts, has well-characterized roles in post-tr

143 sequencing (8-oxoG RIP-seq) to identify 343 RNA transcripts heavily enriched in oxidations in human

144 talled-transcription assay, we revealed that RNA transcripts helped to populate quadruplexes at the e

145 unscrunching states without dissociating the RNA transcript, implying the existence of backtracking t

146 s RNAP-RNA contacts that stabilize the short RNA transcript in the active site and demonstrates that

147 ts with elongating complexes and the nascent RNA transcript in ways that stimulate pausing and termin

148 e an optimised approach for detecting single RNA transcripts in a cell-type specific manner in frozen

149 r transfection agents and recognizing target RNA transcripts in a sequence-specific manner.

150 MBs can be used to image and quantify single RNA transcripts in a wide range of cell lines.

151 Thus, considering the abundance of RNA transcripts in cells, RNA may have a marked impact o

152 action (PCR) was performed to measure HLA-DR RNA transcripts in conjunctival cells taken by impressio

153 PRO-seq) and analyzed nascent mtDNA-encoded RNA transcripts in diverse human cell lines and metazoan

154 c targets in aggressive tumors, we sequenced RNA transcripts in five snap frozen retinoblastomas whic

155 dance and localization of nascent and mature RNA transcripts in fixed, single cells.

156 idization (smFISH) to detect alpha-satellite RNA transcripts in intact human cells.

157 sed a 13-fold increase in HERV-K (HML-2) gag RNA transcripts in Jurkat T cells and a 10-fold increase

158 re we present a strategy to visualize single RNA transcripts in living cells using molecular beacons

159 that RBMBs can also be used to image single RNA transcripts in living cells, when the target RNA is

160 imultaneous visualization of genomic DNA and RNA transcripts in living cells.

161 imultaneous visualization of genomic DNA and RNA transcripts in living cells.

162 Analysis of 5'-capped RNA transcripts in mutant cell lines identified the usag

163 e-copy DNA targets and corresponding nascent RNA transcripts in preimplantation embryos and during sp

164 and distribution of proteins and individual RNA transcripts in single cells.

165 , this study provided global long non-coding RNA transcripts in the blood of patients with KD, IVIG-r

166 cond layer of information is embedded in all RNA transcripts in the form of RNA structure.

167 The catalytic role of RNA transcripts in the GQ formation was strongly suggest

168 Most unwanted RNA transcripts in the nucleus of eukaryotic cells, such

169 acilitates the production of Pol V-dependent RNA transcripts in the RdDM pathway.

170 ory response for both genes and unique small RNA transcripts in the segmental dosage series we tested

171 developed based on digital gene counting of RNA transcripts in urine as a means to detect prostate c

172 Modular analyses of RNA transcripts in whole blood previously identified an

173 In budding yeast, a number of these unwanted RNA transcripts, including spliced-out introns, are firs

174 age cells causes aberrant splicing of myriad RNA transcripts, including those that encode the essenti

175 hase of EBV infection, noncoding EBV-encoded RNA transcripts induced cellular cytokine synthesis, and

176 Single-stranded RNA transcripts induced interferon-beta mediated though

177 Here we show that specific RNA transcript isoforms of alpha-synuclein with an exten

178 Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription

179 ribosomes can bind concurrently to the same RNA transcript, leading to the functional coupling of tr

180 pairing to recognize sequences in messenger RNA transcripts, leading to translational repression and

181 n genes with m6dA are associated with higher RNA transcript levels but identifies allele-specific gen

182 L2 family members based on immunoblotting or RNA transcript levels correlated poorly with the activit

183 demonstrated different (P < 0.05) messenger RNA transcript levels in 148 genes.

184 tial and altitudinal variations in messenger RNA transcript levels of ReCHSs correlating positively w

185 Early studies looking at RNA transcript levels seemed to suggest overexpression i

186 RNA transcript levels were assessed using whole genome m

187 eQTLs are genetic loci that correlate with RNA transcript levels.

188 muscle transcriptome also revealed 461 novel RNA transcripts, likely muscle-expressed long non-coding

189 40 microRNAs and their host long non-coding RNA transcript (lnc-MGC) are coordinately increased in t

190 we report that CCAT2, a novel long noncoding RNA transcript (lncRNA) encompassing the rs6983267 SNP,

191 iously unannotated intergenic long noncoding RNA transcripts (lncRNA) or isoforms that are associated

192 ing NF-Y, p53, and sp1, indicating that such RNA transcripts may function as decoy targets or traps f

193 osed packets can transfer specific proteins, RNA transcripts, microRNAs, and even DNA to target cells

194 here we present evidence that mitochondrial RNA transcripts (mtRNA) are not limited to policystronic

195 which we named myosin heavy-chain-associated RNA transcripts (Myheart, or Mhrt), are cardiac-specific

196 cently uncovered a large number of noncoding RNA transcripts (ncRNAs) in eukaryotic organisms, and th

197 we have identified new sense and anti-sense RNA transcripts, novel mRNAs and mi/siRNA-sized RNA frag

198 se single-genome sequencing to find that the RNA transcripts observed following LRA administration ar

199 tion, up to an ~750-fold reduction, in viral RNA transcripts occurred.

200 ith its host, it is necessary to analyze the RNA transcripts of both the host and pathogen throughout

201 psies after chemotherapy displayed increased RNA transcripts of genes associated with CSCs and TGF-be

202 The RNA transcripts of genes controlled by this mechanism co

203 In Gram-positive bacteria, the RNA transcripts of many amino acid biosynthetic and amin

204 RNA transcripts of mutant poliovirus cDNA clones were tr

205 approach to discover new oncogene-regulated RNA transcripts of potential clinical relevance in cance

206 the amounts of both full-length and internal RNA transcripts of U3-minus vectors are reduced in the n

207 Previous studies have identified a panel of RNA transcripts of very low protein-coding potential in

208 accumulations of both spliced and unspliced RNA transcripts of XMRV and MLV, resulting in their nucl

209 2 of its CTD is detected at the same time as RNA transcripts on nascent DNA.

210 plated DSB repair (R-TDR and c-TDR) using an RNA transcript or a DNA copy of the RNA transcript for D

211 of the 8 internal viral proteins, the viral RNA transcripts, or the host response to these molecules

212 incorporation of synthetic nucleosides into RNA transcripts, particularly at or near the promoter.

213 e consistent inability of cells to recognize RNA transcripts possessing GORS extended to downstream d

214 This variant alters RNA-transcript processing and results in a 222 bp in-fra

215 The RNA transcripts produced from the expanded allele seques

216 The toxic RNA transcripts produced from the mutant allele alter th

217 comparative genomic hybridization (CGH) and RNA transcript profiling, and we compared the genomic di

218 equence, including epigenetic modifications, RNA transcripts, proteins, and metabolites, which togeth

219 thin tens of milliseconds in the presence of RNA transcripts provided justification for the co-transc

220 n through direct incorporation into a target RNA transcript rather than through a traditional antisen

221 uential assembly of the human spliceosome on RNA transcripts regulates splicing across the human tran

222 gle-molecule fluorescence study unveils that RNA transcript release precedes RNA polymerase (RNAP) di

223 In addition, approximately half of the RNA transcripts remain unspliced and either are used to

224 port of partially spliced or unspliced HIV-1 RNA transcripts requires binding of the viral protein re

225 rdinated across numerous introns in metazoan RNA transcripts requires quantitative analyses of transi

226 s) are small sequences of DNA able to target RNA transcripts, resulting in reduced or modified protei

227 ng and increased destruction of nascent TERC RNA transcripts, resulting in telomerase deficiency and

228 studies using high-throughput sequencing of RNA transcripts (RNA-seq) of an isogenic DeltaicgR mutan

229 transcriptome (high-throughput sequencing of RNA transcripts [RNA-seq]) data reveals that few of the

230 (lncRNA) that we named Stem Cell Inhibitory RNA Transcript (SCIRT), which was markedly upregulated i

231 ribed into RNA, and studies with a synthetic RNA transcript sequence demonstrated formation of a high

232 RNA transcript splicing was highly conserved between RFH

233 equivalents/ml, whereas use of a quantified RNA transcript standard showed the same trend but had va

234 odel is the cotranscriptional folding of the RNA transcript, sterically inhibiting the extent of back

235 Non-coding RNA transcripts such as microRNAs (miRNAs) and long non-

236 alyzes both nucleotide addition required for RNA transcript synthesis and excision of incorrect nucle

237 ese structural changes vanish during further RNA transcript synthesis.

238 cterized transgenic plants expressing DvSSJ1 RNA transcripts targeting WCR DvSSJ1 mRNA.

239 rom Rtt103 reduces binding to Rrp6/Trf4, and RNA transcripts terminated by Nrd1(CID(Rtt103)) are pred

240 For some of the RNA transcripts tested, binding and splicing activity of

241 These studies introduce a novel T-cassette RNA transcript that improves RNA display from a four-way

242 2a cluster, also known as 'oncomiR-1', is an RNA transcript that plays a pivotal regulatory role in c

243 us RNAs (ceRNAs) were recently introduced as RNA transcripts that affect each other's expression leve

244 uency in RSV-infected cells and yields small RNA transcripts that are heterogeneous in length but mos

245 ing and analyzing diverse classes of primary RNA transcripts that are of increasing biological intere

246 enome mutation, but also in the diversity of RNA transcripts that are packaged.

247 study at once the entire and complete set of RNA transcripts that are produced by the genome.

248 roRNAs (miRNAs) are small non-protein coding RNA transcripts that can regulate the expression of mess

249 Here, we provide evidence for primary RNA transcripts that circle the genome more than once an

250 While most gene transcription yields RNA transcripts that code for proteins, a sizable propor

251 9, are expressed in Wolbachia from noncoding RNA transcripts that contain precursors with stem-loop s

252 polyadenylation (ApA) to generate messenger RNA transcripts that differ in the length of their 3' un

253 t posttranscriptional modifications of viral RNA transcripts that do not change the nucleotide sequen

254 The identification of the presence of large RNA transcripts that do not code for proteins but that m

255 a sizable proportion of the genome generates RNA transcripts that do not code for proteins, but may h

256 iscovery of extensive transcription of large RNA transcripts that do not code for proteins, termed lo

257 transcriptionally active proteins as well as RNA transcripts that have been subjected to adenosine-to

258 MicroRNAs (miRNAs) are short non-coding RNA transcripts that have the ability to regulate the ex

259 Here, we identify RNA transcripts that overlap the cyclooxygenase-2 (COX-2

260 motifs in the untranslated regions (UTRs) of RNA transcripts that sense metabolite levels and modulat

261 In an RNA transcript, the 2'-OH group at the 3'-terminal nucle

262 is study, we demonstrate successful usage of RNA transcript therapy (RTT) as an exogenous human FXN s

263 Most protein coding genes generate multiple RNA transcripts through alternative splicing, variable 3

264 chains of nucleic acids that target specific RNA transcripts through several mechanisms.

265 st-transcriptional level and use an extended RNA transcript to co-localize all circuit sensing, compu

266 the ability of relatively unstructured model RNA transcripts to activate PKR to inhibit translation,

267 ents and guide Argonaute proteins to nascent RNA transcripts to induce co-transcriptional gene silenc

268 adaptable and expandable system of in vitro RNA transcripts to serve as a combined positive control

269 on regulators into the nucleus and export of RNA transcripts to the cytoplasm.

270 racterized by the ability of a wide range of RNA transcripts to vie for microRNA binding and alleviat

271 ousands of long intergenic non-coding (linc) RNA transcripts, together with recent evidence that linc

272 s Project was launched to contribute maps of RNA transcripts, transcriptional regulator binding sites

273 d for Ser(5)-phosphorylated Pol II and short-RNA transcripts, two hallmarks of transcription initiati

274 iption start sites (TSSs) and validate novel RNA transcripts using Northern blots and luciferase prom

275 ic expression of multiple HTR2A messenger (m)RNA transcript variants.

276 ncode IgM and IgD from heterogeneous nuclear RNA transcripts via alternative splicing, lack intron an

277 By comparing and characterizing these RNA transcripts, we conclude that the mechanism of speci

278 of exonic sequences in the splicing of human RNA transcripts, we conducted saturation mutagenesis of

279 Furthermore, full-length RNA transcripts were also defective in terms of nuclear

280 , tryptase, and carboxypeptidase A messenger RNA transcripts were detected by quantitative reverse tr

281 RNA transcripts were extremely stable, showing minimal d

282 Circular RNA transcripts were first identified in the early 1990s

283 we report here that some of these C. parvum RNA transcripts were selectively delivered into the nucl

284 cation of a considerable amount of noncoding RNA transcripts, which are increasingly recognized for t

285 ort of unspliced and partially spliced viral RNA transcripts, which encode the viral genome and the g

286 cies such as long noncoding RNA and circular RNA transcripts whose presence had not been previously o

287 emains unresolved because replacement of the RNA transcript with a neocassette has no obvious phenoty

288 mation of fully modified and highly emissive RNA transcripts with (th)G replacing all guanosine resid

289 of transcribing novel unspliced forms of HIV-RNA transcripts with competent open reading frames (ORFs

290 In pull-down assays, ZAP bound to viral RNA transcripts with either CpG- and UpA-high sequences

291 IDH1 binds to thousands of RNA transcripts with enriched functions in transcription

292 ts (SNVs) in exons and introns on individual RNA transcripts with high efficiency.

293 s efficient m(6)A installation in endogenous RNA transcripts with high specificity.

294 R loops arise from hybridization of RNA transcripts with template DNA during transcription.

295 e learning algorithms, scRCAT-seq demarcates RNA transcripts with unprecedented accuracy.

296 detected </=10 copies/reaction of quantified RNA transcripts, with a linear dynamic range of 8 log un

297 is cotranscriptionally recruited to nascent RNA transcripts, with particular enrichment at intronic

298 quires localizing the sequences of expressed RNA transcripts within a cell in situ.

299 be used to accurately quantify the number of RNA transcripts within individual cells.

300 e possibility of ab initio reconstruction of RNA transcripts without appealing to the ontology of "GT