ライフサイエンスコーパス: RNA-binding

1 ixing a conformation that is compatible with RNA binding.

2 e in proper incorporation of nucleotides and RNA binding.

3 The OB-fold and the beta-HP contribute to RNA binding.

4 We observed that despite its RNA-binding ability, Gag expression does not alter the p

5 In addition, we characterize RNA-binding activities of novel RBPs that have been recu

6 This approach yields estimates of in vivo RNA-binding activities that identify subunits within mul

7 Mutagenesis experiments show that the RNA binding activity of Mov10 is required for HCV inhibi

8 In line with the double-stranded RNA-binding activity of EBP1 in human (Homo sapiens) cel

9 In all cases, the RNA-binding activity of S1 is a central feature of its f

10 m for how NasR couples its nitrate signal to RNA-binding activity, and generally show how signal-resp

11 ond, in agreement with an increased apparent RNA-binding affinity of the N196K-substituted protein.

12 ems to investigate viral genome replication, RNA-binding affinity, ATP hydrolysis activity, and helic

13 Here, we measure Rrp6p-RNA binding and degradation kinetics in vitro at single-

14 positive electrostatic potentials (PEP) for RNA binding and dimer stabilization.

15 the formation of the virus compartment with RNA binding and how these activities are modulated by th

16 quences known as zipcodes that interact with RNA binding and motor proteins.

17 and cOA generation activities require target RNA binding and recognition of distinct target RNA 3' pr

18 cay, which is dependent on sequence-specific RNA binding and splicing.

19 ow dimerization/multimerization is linked to RNA binding and virion packaging for HIV-1 restriction.

20 in-of-function involving direct and aberrant RNA-binding and strengthen the link between two motor ne

21 proteins have evolved to exert control over RNA-binding ANTAR domains.

22 n alternative to l-RNA for the generation of RNA-binding aptamers, providing a robust and practical a

23 omplex via mutational analysis combined with RNA-binding assays and cell-based frameshifting reporter

24 ated in providing essential contributions to RNA-binding, but not DNA-binding, affinity.

25 Here, we study RNA binding by a small recombinant construct of the DGCR

26 Heat shock induced progressive loss of 5' RNA binding by initiation factors over ~16 min and provo

27 sis of malM 3'-UTR mutants showed that tight RNA binding by the ProQ NTD required a terminator hairpi

28 RNA-binding domains (RBDs), whose integrated RNA-binding capacity determines whether LLPS occurs upon

29 Our study thus reveals that the RNA-binding capacity of uL18 ribosomal proteins has been

30 reement between species, we propose that the RNA-binding characteristics we observe in fission yeast

31 to its targets according to the current PPR-RNA binding code.

32 ease of L13a from 60S ribosome, formation of RNA-binding complex, and subsequent GAIT element-mediate

33 Large RNA-binding complexes play a central role in gene expres

34 chemical inhibitor of transcription or by an RNA-binding-defective mutant all disrupted PRC2 chromati

35 In this study, we found that RNA binding-deficient TDP-43 (produced by neurodegenerat

36 ing its deaminase domain and double stranded RNA binding domain 2 (dsRBD2) bound to an RNA duplex as

37 s identify the LOTUS domain as a specialized RNA binding domain across phyla and underscore the molec

38 r RNAs (mRNAs) via a high-affinity stem-loop RNA binding domain interaction, enabling high-throughput

39 Despite originally predicted as an RNA binding domain, its molecular binding activity towar

40 rich C-terminal part instead of the last KH RNA binding domain.

41 We demonstrated previously that the NS1 RNA-binding domain (NS1(RBD)) interacts directly with th

42 ng and ribosome maturation (CRM) domain is a RNA-binding domain found in a plant-specific protein fam

43 motif was not bound by the conventional C3H1 RNA-binding domain of ZC3H12B.

44 equences outside of the conserved PUF family RNA-binding domain.

45 promotes oogenesis and contains a number of RNA binding domains, including two RRMs and multiple LOT

46 the DGCR8 core, contains two double-stranded RNA-binding domains (dsRBDs) and a C-terminal tail.

47 zygous variant in one of the double-stranded RNA-binding domains (dsRBDs) was identified.

48 a genome-scale collection of RBPs and their RNA-binding domains (RBDs) and assessed their specificit

49 Nucleolin, through its RNA-binding domains (RBDs), binds to and maintains the c

50 iewed as interconnected complexes (nodes) of RNA-binding domains (RBDs), whose integrated RNA-binding

51 he structure and function of seventeen known RNA-binding domains and analyze the hydrogen bonds adopt

52 The individual RNA-binding domains of hnRNPK work together to interact

53 The N protein contains two RNA-binding domains surrounded by regions of intrinsic d

54 lly disordered regions in addition to folded RNA-binding domains.

55 at have surface spikes and putative internal RNA-binding domains.

56 RNA binding experiments together with genome editing dem

57 s-acting elements, alternative splicing, and RNA-binding factors.

58 We conclude that PRC2 requires RNA binding for chromatin localization in human pluripot

59 Here, we investigate the RNA binding function of ATRX, a chromatin remodeler with

60 Global mapping of STRAP-RNA binding in mouse embryos by enhanced-CLIP sequencing

61 ted class II IN substitutions compromised IN-RNA binding in virions by one of the three distinct mech

62 a high-affinity/low-specificity paradigm for RNA binding in vitro and in vivo.

63 Integrative analysis of the ZMAT3 RNA-binding landscape and transcriptomic profiling revea

64 Using an RNA-binding lysine-rich region, DZIP3 interacted with th

65 The data support a model in which only one RNA-binding mode is critical for virion packaging and re

66 y bind two of these motifs by connecting two RNA-binding modules with peptoid linkers of different ge

67 n created by novel combinations of dedicated RNA-binding modules.

68 acids 2 to 8 of the N-proximal arginine-rich RNA binding motif.

69 24 h, revealed significant changes only for RNA-binding motif 3 (Rbm3).

70 eIF2D requires its RNA-binding motif for regulation of 5' leader-mediated A

71 RBP negatively regulating ERV expression was RNA-binding motif protein 4 (RBM4).

72 the unprecedented finding that the conserved RNA-binding motif protein, RBM24, positively controls So

73 coding the pathogenic R636S variant of human RNA-binding motif protein-20 (RBM20), we discovered that

74 we test the possibility that the multivalent RNA-binding nucleocapsid protein (N) from severe acute r

75 Here, we used native MS to investigate RNA binding of wild-type (WT) Gag and Gag lacking the p6

76 RNA-binding pentatricopeptide repeat (PPR) proteins spec

77 m of energy transduction between the ATP and RNA binding pockets using molecular dynamics simulations

78 pair splicing recognition or by altering the RNA-binding preferences of individual splicing factors.

79 However, whether similar RNA-binding properties can be achieved using aptamers co

80 Here, we investigated the RNA-binding properties of human RPA and its possible rol

81 a from our lab implicate autoimmunity to the RNA binding protein (RBP) heterogeneous nuclear ribonucl

82 translation of distinct mRNA isoforms of the RNA binding protein (RBP), Elavl4, in radial glia progen

83 he m6A reader protein YTH N6-methyladenosine RNA binding protein 2 (YTHDF2) promotes mRNA decay durin

84 Release factor homolog C12orf65 (mtRF-R) and RNA binding protein C6orf203 (MTRES1) eject the nascent

85 This motif binds the RNA binding protein FMR1 and directs miRNA loading into

86 We demonstrate how RNA binding protein FOX-1 functions as a dose-dependent

87 or pathologically associated with tau (e.g. RNA binding protein HNRNPA1).

88 asts) are controlled by the highly conserved RNA binding protein Imp (IGF2BP), via one of its top bin

89 Blocking PKR using PKR-K296R, the TAR RNA binding protein or PKR-KO cells, reduces RAN protein

90 Integrator is another RNA binding protein recruited to the promoters and enhan

91 cular junction is regulated by the conserved RNA binding protein Syncrip/hnRNP Q.

92 The RNA binding protein TDP-43 forms intranuclear or cytopla

93 le X Mental Retardation Protein (FMRP) is an RNA binding protein that regulates translation and is re

94 f the FMR1 gene and loss of encoded FMRP, an RNA binding protein that represses translation of some o

95 From this screen, we identified an RNA binding protein, Musashi (msi), as one of the possib

96 DEAH-box RNA helicase Mtr4 together with an RNA-binding protein (Air1 or Air2) and a poly(A) polymer

97 nonclassical NLSs within the cold-inducible RNA-binding protein (CIRBP).

98 Extracellular cold-inducible RNA-binding protein (eCIRP) is a damage-associated molec

99 ulated during development through changes in RNA-binding protein (RBP) activities.

100 imidine tract-binding protein 1 (PTBP1) is a RNA-binding protein (RBP) expressed throughout B cell de

101 etween the oncogenic microRNA miR-21 and the RNA-binding protein (RBP) human antigen R (HuR) in respo

102 constrained, and enriched for cis-eQTLs and RNA-binding protein (RBP) interactions.

103 tified that La-related protein 4 (LARP4), an RNA-binding protein (RBP) known to enhance mRNA stabilit

104 Recent studies suggest that the RNA-binding protein (RBP) ZMAT3 is important in mediatin

105 RNA-binding protein (RBP)/helicase DDX3 (DEAD-box helica

106 to the canonical CBP20-CBP80 CBC, and/or an RNA-binding protein - possibly in association with the e

107 identify and characterize a conserved SMALL RNA-BINDING PROTEIN 1 (SRBP1) family that mediates non-c

108 as9 (dCas9)-based CARRY (CRISPR-assisted RNA-RNA-binding protein [RBP] yeast) two-hybrid assay to ass

109 le X mental retardation protein (FMRP) is an RNA-binding protein abundant in the nervous system.

110 activity for the Drosophila Argonaute family RNA-binding protein AGO1, a component of the miRNA-depen

111 Although an established RNA-binding protein and histone methyltransferase, EZH2

112 MAARS interacts with HuR/ELAVL1, an RNA-binding protein and important regulator of apoptosis

113 targets of La-related protein 1 (LARP1), an RNA-binding protein and mTORC1 effector that has been sh

114 ptionally stabilized by interacting with the RNA-binding protein ApELAV.

115 tudy in Arabidopsis that employed a designer RNA-binding protein as a psbA RNA affinity tag.

116 mphocytes expressed Lin28b, which encodes an RNA-binding protein associated with fetal hematopoietic

117 LS) and frontotemporal dementia (FTD)-linked RNA-binding protein called FUS (fused in sarcoma) has be

118 Deleted in azoospermia-like (DAZL) is an RNA-binding protein critical for gamete development.

119 ore, our results showed increased binding of RNA-binding protein CUGBP1 with occludin and E-cadherin

120 ins, suggesting a feedback between effective RNA-binding protein dosage and protein quality control i

121 Tristetraprolin (TTP), an RNA-binding protein encoded by the ZFP36 gene, is vital

122 CRISPR knockout of LIN28B-an oncofetal RNA-binding protein exerting diverse effects via negativ

123 La-related protein 6 (Larp6) is a conserved RNA-binding protein found across eukaryotes that has bee

124 SERBP1 is the first example of an RNA-binding protein functioning as a central regulator o

125 Mutations in the RNA-binding protein FUS cause amyotrophic lateral sclero

126 Dysregulation of the DNA/RNA-binding protein FUS causes certain subtypes of ALS/F

127 es, such as the 214-residue LC domain of the RNA-binding protein FUS, is particularly intriguing from

128 The RNA-binding protein fused in sarcoma (FUS) can form path

129 Mutations in the RNA-binding protein Fused in Sarcoma (FUS) cause early-o

130 The RNA-binding protein fused in sarcoma (FUS) forms physiol

131 Here, we report that the RNA-binding protein HuR (ELAVL1) forms complexes with NA

132 Here, we investigated the role of RNA-binding protein HuR (human antigen R) in the posttra

133 iting p53 protein synthesis by degrading the RNA-binding protein HuR in response to UV radiation.

134 umanized livers through its interaction with RNA-binding protein HuR.

135 Here, we report the identification of the RNA-binding protein HuR/ELAVL1 as a central oncogenic dr

136 in sarcoma (FUS) is a ubiquitously expressed RNA-binding protein implicated in familial ALS and front

137 ding to a toxic protein or RNA binding to an RNA-binding protein in the case of liquid-liquid phase s

138 factor receptor A (PDGFRA), as well as novel RNA-binding protein interactors ZC3H14 (zinc finger CCCH

139 n-29a, and of HBL-1 for lin-29b, whereas the RNA-binding protein LIN-28 coordinates LIN-29 isoform ac

140 proteomic analyses, we demonstrate that the RNA-binding protein LIN28B, which is developmentally exp

141 lls (HSPCs) caused by high expression of the RNA-binding protein Lin28b.

142 cing, RNA editing, nuclear pore composition, RNA-binding protein motif enrichment, and RNA secondary

143 Evolutionarily conserved RNA-binding protein Musashi1 (Msi1) can regulate develop

144 e assembly requires NEAT1 recruitment of the RNA-binding protein NONO, however the NEAT1 elements res

145 Hfq is an RNA-binding protein present in diverse bacterial lineage

146 cytes to functional neurons by depleting the RNA-binding protein PTB (also known as PTBP1).

147 eracting this mechanism, the multifunctional RNA-binding protein PTBP1 regulates the balance of short

148 cepts through experimental examples with the RNA-binding protein Puf4.

149 regulation of a non-muscle splice isoform of RNA-binding protein RBFOX2 in DM1 heart tissue-due to al

150 f lincNORS requires the presence of RALY, an RNA-binding protein recently found to be implicated in c

151 on mRNA using amyloid-like assemblies of the RNA-binding protein Rim4.

152 We identify the RNA-binding protein SERBP1 as a novel regulator of gliob

153 l level and involves an interaction with the RNA-binding protein TAR DNA-binding protein 43 kDa (TDP-

154 zer, and then, graphically displays enriched RNA-binding protein target sites.

155 Aberrant aggregation of the RNA-binding protein TDP-43 in neurons is a hallmark of f

156 The RNA-binding protein TDP-43 is present in several MLOs, u

157 Mutations in TARDBP, encoding the RNA-binding protein TDP-43, are one cause of ALS, and TD

158 hyperexcitability and mislocalization of the RNA-binding protein TDP43 are highly conserved features

159 In this study, we use Staufen, an RNA-binding protein that colocalizes with osk mRNA, as a

160 The FinO-domain-protein ProQ is an RNA-binding protein that has been known to play a role i

161 CSTF2 encodes an RNA-binding protein that is essential for mRNA cleavage

162 indings demonstrate that FUS is an important RNA-binding protein that mediates translational repressi

163 pathogen Pseudomonas aeruginosa, RsmA is an RNA-binding protein that plays critical roles in the con

164 ZFP36L1 is a tandem zinc-finger RNA-binding protein that recognizes conserved adenylate-

165 Pumilio is an RNA-binding protein that represses a network of mRNAs to

166 of a long 26 hr period phenotype, encodes an RNA-binding protein that stabilizes the ck-1a transcript

167 otein kinase 2 (MK2) but is inhibited by the RNA-binding protein tristetraprolin (TTP, encoded by the

168 kely mechanism of splicing repression by the RNA-binding protein UNC-75/CELF via interactions with ci

169 The decay pathway requires the RNA-binding protein UPF1 and its associated protein G3BP

170 TDP-43 is an RNA-binding protein which forms aggregates in neurons of

171 ZC3H14 has recently emerged as an important RNA-binding protein with multiple roles in posttranscrip

172 RNA-binding protein ZFP36L1 functions as a tumor suppres

173 FUS is a nuclear RNA-binding protein, and its cytoplasmic aggregation is

174 ite excitement around ProQ as a novel global RNA-binding protein, and its potential to serve as a mat

175 We could validate RBMS1, a barely described RNA-binding protein, as a new target gene for oncogenic

176 Aggregates of a prion-like RNA-binding protein, cytoplasmic polyadenylation element

177 y describes an unexpected mechanism by which RNA-binding protein, MBNL1, activity is inhibited in hyp

178 NONO is a DNA/RNA-binding protein, which plays a critical regulatory r

179 omal homologue-1 (FXR1) is a muscle-enriched RNA-binding protein.

180 show that ZC3H5 is an essential cytoplasmic RNA-binding protein.

181 ified as binding sites for NC, a Gag-derived RNA-binding protein.

182 captures global structural features, such as RNA-binding-protein binding sites and reactivity differe

183 Finally, we observed a DNV burden in RNA-binding-protein regulatory sites (OR = 1.13, 95% CI

184 Here, we show that three ELAV/Hu RNA binding proteins (Elav, Rbp9, and Fne) have similar

185 on of a newly synthesized mRNA by a class of RNA binding proteins (ELAVs).

186 Computational prediction of RNA binding proteins (RBP) motifs and UV-cross-linking a

187 RNA binding proteins (RBPs) are a large protein family t

188 The crosslinked RNA binding proteins (RBPs) are purified by solid-phase

189 RNA binding proteins (RBPs) are the primary gene regulat

190 RNA binding proteins (RBPs) frequently regulate the expr

191 The cell-context dependency for RNA binding proteins (RBPs) mediated control of stem cel

192 to study the in vivo regulatory networks of RNA binding proteins (RBPs).

193 A growing body of evidence indicates that RNA binding proteins control an array of processes in be

194 by small RNAs in Escherichia coli depends on RNA binding proteins Hfq and ProQ, which bind mostly dis

195 To identify RNA binding proteins potentially driving these patterns,

196 he binding motifs and expression patterns of RNA binding proteins with exon splicing profiles, we unc

197 RNAs, and that they bound a diverse array of RNA binding proteins, including p300 but not CBP.

198 es of TRAMP components with multiple nuclear RNA binding proteins, revealing preferential colocalizat

199 39 cassette exons enriched in genes encoding RNA binding proteins.

200 rough the targeting of selectively essential RNA binding proteins.

201 ieving multivalency and can accommodate many RNA binding proteins.

202 icles (RNPs), complexes containing mRNAs and RNA binding proteins.

203 d that three maternally deposited Drosophila RNA-binding proteins (ME31B, Trailer Hitch [TRAL], and C

204 a highly interconnected network enriched in RNA-binding proteins (RBPs) and EV cargoes.

205 ybrid screen for interactions between murine RNA-binding proteins (RBPs) and motor proteins, here we

206 Interactions between RNA-binding proteins (RBPs) and RNAs are critical to cel

207 ce of a standard TRIzol extraction to enrich RNA-binding proteins (RBPs) and their cognate bound RNA.

208 RNA-binding proteins (RBPs) are key mediators of RNA met

209 RNA-binding proteins (RBPs) comprise a large class of ov

210 RNA-binding proteins (RBPs) function as master regulator

211 using mouse models, we explored the role of RNA-binding proteins (RBPs) in regulation of the biologi

212 Oligomeric assemblies of tau and the RNA-binding proteins (RBPs) Musashi (MSI) are reported i

213 ng the interaction mechanism and location of RNA-binding proteins (RBPs) on RNA is critical for under

214 RNA-binding proteins (RBPs) play crucial roles in almost

215 RNA-binding proteins (RBPs) play key roles in post-trans

216 The molecular functions of the majority of RNA-binding proteins (RBPs) remain unclear, highlighting

217 mediated mRNA decay and associate with major RNA-binding proteins (RBPs) such as Hfq and ProQ.

218 Here, we uncover a network of RNA-binding proteins (RBPs) that enhances the translatio

219 ng individual guide RNAs (gRNA), we identify RNA-binding proteins (RBPs) that influence the formation

220 zinc finger (TZF) domains are found in many RNA-binding proteins (RBPs) that regulate the essential

221 s in the human genome that are recognized by RNA-binding proteins (RBPs), generated as part of the En

222 The human genome encodes for over 1,500 RNA-binding proteins (RBPs), which coordinate regulatory

223 cytoplasmic condensates are rich in RNA and RNA-binding proteins (RBPs), which undergo liquid-liquid

224 ssion of RNA requires the action of multiple RNA-binding proteins (RBPs).

225 d protein components of complexes of RNA and RNA-binding proteins (RBPs).

226 ntial for their function and are mediated by RNA-binding proteins (RBPs).

227 ironmental stress are frequently mediated by RNA-binding proteins (RBPs).

228 RNA-binding proteins (RNA-BPs) play critical roles in de

229 d networks of both transcription factors and RNA-binding proteins (TFs and RBPs).

230 les (MLOs), which majorly consist of RNA and RNA-binding proteins and are formed via liquid-liquid ph

231 mpetition for binding sites among protective RNA-binding proteins and decay factors, PTBP1 promotes d

232 Consequently, RNA-binding proteins and mRNA-encoded sequence elements

233 ented by low-complexity regions from certain RNA-binding proteins and proteins that form condensates

234 Yet, the roles of many RNA-binding proteins are not understood.

235 are degraded by the proteasome, we uncovered RNA-binding proteins as high-confidence substrates that

236 recruited in phase-separated forms of human RNA-binding proteins associated with SG formation.

237 establish that non-amyloid self-assembly of RNA-binding proteins can drive a form of epigenetics bey

238 s that RsmA associates with and that the two RNA-binding proteins can exert regulatory effects on com

239 We find that two PUF family RNA-binding proteins FBF-1 and FBF-2 have opposite effec

240 We additionally show that the related RNA-binding proteins hnRNPF and hnRNPH bind directly to

241 In this study, we used TRIBE (targets of RNA-binding proteins identified by editing) as an approa

242 Opposing gradients of two RNA-binding proteins Imp and Syp comprise the intrinsic

243 e fragile X protein family consists of three RNA-binding proteins involved in translational regulatio

244 RNA-binding proteins like human antigen R (HuR) are key

245 ght the exquisite specificity that conserved RNA-binding proteins like RBM24 mediate in the post-tran

246 evidence that it specifically interacts with RNA-binding proteins or mRNA.

247 Consequently, RNA-binding proteins play a critical role in the regulat

248 The sequence-specific RNA-binding proteins PTBP1 (polypyrimidine tract-binding

249 Here we show that the Xist RNA-binding proteins PTBP1(9), MATR3(10), TDP-43(11) and

250 Our analysis of RNA-binding proteins reveals ILF3 as a potential regulat

251 oth RG/RGG and RSY regions in numerous other RNA-binding proteins suggests that the interaction of TN

252 otemporal gene regulation is often driven by RNA-binding proteins that harbor long intrinsically diso

253 FUS (fused in sarcoma) are aggregation-prone RNA-binding proteins that in ALS can mislocalize to the

254 tids such as trypanosomes depends heavily on RNA-binding proteins that influence mRNA decay and trans

255 post-transcriptional gene control, often via RNA-binding proteins that use a YT521-B homology (YTH) d

256 -containing complexes reproducibly contained RNA-binding proteins that were previously found associat

257 we devised a cell-based functional screen of RNA-binding proteins using a let-7 sensor luciferase rep

258 umulating evidence suggests participation of RNA-binding proteins with intrinsically disordered domai

259 repetitive RNA, which negatively sequesters RNA-binding proteins(5) before its non-canonical transla

260 recruiting aggregates, stress granules, and RNA-binding proteins, directing their elimination and as

261 s of human and mouse NMD targets, especially RNA-binding proteins, encode potential Split-ORFs, some

262 P1 family proteins have long been considered RNA-binding proteins, however, our results identified 40

263 7 biogenesis is tightly regulated by several RNA-binding proteins, including Lin28A/B, which represse

264 We focused on two RNA-binding proteins, RALY and hnRNP-C, which we confirm

265 1 is recruited to mRNAs by sequence-specific RNA-binding proteins, resulting in stabilization of the

266 meric condensate that consists of ubiquitous RNA-binding proteins, revealing an unanticipated mechani

267 QTLs and are enriched with binding sites of RNA-binding proteins, RNA structure-changing variants an

268 s and destabilizing interactions with varied RNA-binding proteins, suggest that RNA pseudouridylation

269 on the crosstalk between cell signaling and RNA-binding proteins.

270 HUA-PEP activity, composed of genes encoding RNA-binding proteins.

271 e method's wide applicability in identifying RNA-binding proteins.

272 tion of similar mechanisms governed by other RNA-binding proteins.

273 d caps, as well as through sequence-specific RNA-binding proteins.

274 ce of mRNA leaders that use riboswitches and RNA-binding proteins.

275 S directly alters intron retention levels in RNA-binding proteins.

276 ociated proteins, transcription factors, and RNA-binding proteins.

277 low-complexity regions from self-associating RNA-binding proteins.

278 , and occupancy by transcription factors and RNA-binding proteins.

279 ligo(dT) capture, and proteomics to identify RNA-binding proteomes.

280 r DNA-binding (Q2 = 81 +/- 0.9%) followed by RNA-binding (Q2 = 80 +/- 1%) and worst for protein-prote

281 The development of structure-specific RNA binding reagents remains a central challenge in RNA

282 We identify ATRX RNA binding regions (RBRs) and discover that the major A

283 Yet, the biological importance of this RNA binding remains unsettled.

284 DZIP3/hRUL138 is a poorly characterized RNA-binding RING E3-ubiquitin ligase with functions in e

285 id protein is comprised of three domains: R (RNA binding), S (shell), and P (protruding).

286 Ifit1 is similar to human IFIT1 in its cap0-RNA-binding selectivity, the roles of Ifit1b and Ifit1c

287 locations of amino acid side chains altering RNA binding sites in the RRM.

288 pite their central role in RNA function, the RNA-binding specificities of most RBPs remain unknown or

289 nzymatic probing with RNases illuminated how RNA binding specificity and dissociation after cleavage

290 dentified by each study, suggesting that the RNA-binding specificity of FMRP is still unknown.

291 To further investigate the RNA-binding specificity of FMRP, we developed a new meth

292 monstrate that FUS acetylation regulates the RNA binding, subcellular localization and inclusion form

293 scaffold with basic patches constituting an RNA-binding surface exhibiting a preference for binding

294 which suggested dimerization mechanisms and RNA binding surfaces, whereas the dimerization appeared

295 We demonstrate that, through ATP-dependent RNA binding, the DEAD-box protein eIF4A reduces RNA cond

296 eric inhibitor binding to a toxic protein or RNA binding to an RNA-binding protein in the case of liq

297 gnition motif, K315/K316 acetylation reduced RNA binding to FUS and decreased the formation of cytopl

298 ere, we mapped the genetic basis to Ssd1, an RNA-binding translational regulator that is functional i

299 purified mRNPs, and transcriptome-wide UPF1 RNA binding, we present the mechanistic basis for inhibi

300 Further, by integrating RNA binding with cardiac transcriptome datasets from DM1