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1 , which contains a conserved double-stranded RNA binding domain.
2 makes up almost the entirety of APO1, is an RNA binding domain.
3 e common Cys(3)His zinc finger polyadenosine RNA binding domain.
4 nuclear pore protein Nup153 contains a novel RNA binding domain.
5 sociates relatively robustly with the Nup153 RNA binding domain.
6 -dimensional structure of a highly conserved RNA binding domain.
7 eat domains on either side of the C-terminal RNA binding domain.
8 ified a C-terminal region in Hel2/Rqt1 as an RNA binding domain.
9 eta is specifically targeted to mRNAs by its RNA binding domain.
10 cognition Motif (RRM) is the most ubiquitous RNA binding domain.
11 rich C-terminal part instead of the last KH RNA binding domain.
12 ilar CCCH zinc fingers that form the primary RNA binding domain.
13 was identified as a putative double-stranded RNA-binding domain.
14 ession through interactions with the Pumilio RNA-binding domain.
15 inal RNMT-activating domain and a C-terminal RNA-binding domain.
16 rginine-rich region, which overlaps with its RNA-binding domain.
17 o tagged derivatives of the spliceosomal U1A RNA-binding domain.
18 to a response regulator (EutV) containing a RNA-binding domain.
19 K51A substitution in the Tat double-stranded RNA-binding domain.
20 ing that DUF860 is a previously unrecognized RNA-binding domain.
21 a novel Sec incorporation domain and an L7Ae RNA-binding domain.
22 eir rapid decay via its conserved C-terminal RNA-binding domain.
23 omoting SECIS and eEFSec binding to the SBP2 RNA-binding domain.
24 hback) if Nanos is tethered via an exogenous RNA-binding domain.
25 on in humans, lies within a novel, bipartite RNA-binding domain.
26 ole of the N-terminal domain as an accessory RNA-binding domain.
27 otease activity or by the positively charged RNA-binding domain.
28 s suggest that EIAV Rev utilizes a bipartite RNA-binding domain.
29 as HicA (COG1724) contains a double-stranded RNA-binding domain.
30 d that GR-DBD is a robust structure-specific RNA-binding domain.
31 aptation of both zinc fingers within the TTP RNA-binding domain.
32 through its RS domains but also through its RNA-binding domain.
33 RMs), the most prevalent class of eukaryotic RNA-binding domain.
34 equences outside of the conserved PUF family RNA-binding domain.
35 protein kinase R (PKR) independently of its RNA-binding domain.
36 icing factors, in that they contain a single RNA-binding domain.
37 dopsis PUF protein that contains an atypical RNA-binding domain.
38 n bind engineered proteins fused to specific RNA binding domains.
39 rotein contains two structurally independent RNA binding domains.
40 one fold that is similar to that of RNP-type RNA binding domains.
41 motif (RRM), which is one of the most common RNA binding domains.
42 nd SAFB, a nuclear protein with both DNA and RNA binding domains.
43 partners by the combinatorial use of several RNA binding domains.
44 ins (RBPs), many of which lack characterized RNA binding domains.
45 ribosomal proteins via remodelling of their RNA-binding domains.
46 intramolecular interactions between the two RNA-binding domains.
47 at have surface spikes and putative internal RNA-binding domains.
48 to phosphorylate eIF2alpha even without its RNA-binding domains.
49 h proteins have CCCH type tandem zinc finger RNA-binding domains.
50 ences appended to their conserved PUF repeat RNA-binding domains.
51 e separate from the two pairs of zinc-finger RNA-binding domains.
52 Dicer proteins is related to double-stranded RNA-binding domains.
53 osed interaction between G3BP1 RGG and RIG-I RNA-binding domains.
54 ated by the combinatorial action of multiple RNA-binding domains.
55 s largely limited to proteins carrying known RNA-binding domains.
56 lly disordered regions in addition to folded RNA-binding domains.
57 ally based on a number of well-characterised RNA-binding domains.
58 st a therapeutic potential for SRSF1 and its RNA-binding domains.
59 ing its deaminase domain and double stranded RNA binding domain 2 (dsRBD2) bound to an RNA duplex as
60 localization of oskar mRNA requires Staufen RNA binding domain 2, whereas prospero mRNA localization
62 alization mediated the binding of Miranda to RNA binding domain 5, suggesting that different Staufen
64 We found that the C696R substitution in the RNA-binding domain abrogates SECIS binding and does not
65 lly, we also detect several proteins with an RNA-binding domain abundant in Apicomplexans (RAP domain
66 ray of octatricopeptide repeats (OPR) and an RNA-binding domain abundant in apicomplexans (RAP) domai
67 an unusual RNA-binding domain named RAP (for RNA-binding domain abundant in Apicomplexans), shared by
68 s identify the LOTUS domain as a specialized RNA binding domain across phyla and underscore the molec
71 nspecific RNA binding by the double-stranded RNA binding domain, an interaction that is essential for
72 N proteins contain two structurally distinct RNA-binding domains, an unusual characteristic among RNA
73 Rsr is composed of two domains: a helical RNA binding domain and a mixed "von Willebrand factor A-
74 e PKR constructs lacking the double-stranded RNA binding domain and bind to a basic region adjacent t
76 valent interactions with the double stranded RNA binding domain and the basic region underlie the abi
77 he individually determined structures of the RNA binding domain and the effector domain from non-H5N1
78 istance distribution functions of the U2AF65 RNA binding domain and those either previously observed
79 ition of the small RNA substrate by multiple RNA binding domains and the methyltransferase domain in
83 lanogaster demonstrates how a well-conserved RNA-binding domain and cognate binding sequence have bee
86 DLC-1 directly binds to FBF-2 outside of the RNA-binding domain and promotes FBF-2 localization and f
87 and contained nucleolar localization signal, RNA-binding domain and several phosphorylation sites.
88 d by RNA-binding proteins that consist of an RNA-binding domain and two reiterated phosphotransferase
89 he structure and function of seventeen known RNA-binding domains and analyze the hydrogen bonds adopt
91 tains both potential 5' cap and 5' phosphate RNA-binding domains and interacts with capped 21U precur
93 losses and acquisitions of diverse putative RNA-binding domains and the acquisition of an Archaea-li
94 erminal region of the protein that lacks the RNA-binding domains and uridyltransferase activity of th
96 ction are homodimerization of its kinase and RNA-binding domains, and autophosphorylation at the resi
97 ng antiviral properties of this protein, the RNA-binding domains, and the minimal effects observed on
98 cture, with both zinc knuckle and cold shock RNA-binding domains, and were originally identified as r
99 other topoisomerases, contains a distinctive RNA-binding domain; and deletion of this domain diminish
101 he distal alpha-helix of the double-stranded RNA-binding domains are necessary to engage structural f
104 virions we identified the second of the two RNA-binding domains as a principal determinant of MHV pa
105 oteins within these bodies contain KH or RRM RNA-binding domains as well as low complexity (LC) seque
106 analysis indicates that the two double stand RNA binding domains at the N-terminus of RHA are respons
107 o alpha-beta-beta-beta-alpha double-stranded RNA-binding domains at the N terminus and repeated argin
109 minimal RNA fragment that are key to Nup153 RNA-binding domain binding and demonstrated that the bin
111 ristics, the X-ray structure of the U2AF(65) RNA binding domain bound to a Py tract composed of seven
112 ined four structures of an extended U2AF(65)-RNA-binding domain bound to Py-tract oligonucleotides at
113 RSF1 deletion mutants containing the protein RNA-binding domains but not the arginine serine-rich act
114 tructure, including the presence of putative RNA-binding domains, but to what extent they provide fun
115 family of RNA-binding proteins share similar RNA-binding domains by which they regulate the translati
116 in Dim2, providing another example where an RNA-binding domain can be repurposed for protein interac
118 substrate and that removal of its KH and S1 RNA-binding domains can reduce enzyme processivity witho
119 Both the N-terminal domain (containing an RNA-binding domain characterized by the presence of five
120 ons, we detected a divergent double-stranded RNA-binding domain coinciding with the DUF283 of Dicer.
122 ally to mRNA targets using a single-stranded RNA-binding domain comprising eight Pumilio (PUM) repeat
123 e mRNA led to the conclusion that the Nup153 RNA binding domain confers a general affinity for single
125 Here, we have used analogues of the TTP RNA-binding domain containing specific tryptophan substi
126 rotein contains two structurally independent RNA binding domains, designated the N-terminal domain (N
127 ere, the solution conformation of the U2AF65 RNA binding domain determined using small angle x-ray sc
128 RNA intermediate, and mutations in the pTRS1 RNA binding domain did not affect PKR binding or inhibit
129 RNA recognition to decipher how this unique RNA binding domain discriminates between potential targe
130 es, both of which required a double-stranded RNA-binding domain (dsRBD) and a functional helicase mot
131 specific interactions by its double-stranded RNA-binding domain (dsRBD) helix alpha1 to the tetraloop
132 odular enzymes with multiple double-stranded RNA binding domains (dsRBDs) and a catalytic domain.
134 the DGCR8 core, contains two double-stranded RNA-binding domains (dsRBDs) and a C-terminal tail.
136 specific protein TRBP, whose double-stranded RNA-binding domains (dsRBDs) interact with the A-form ge
138 affinities of dsRNAs to PKR double-stranded RNA-binding domains (dsRBDs) were determined by isotherm
141 associates with E3 ubiquitin ligases bearing RNA-binding domains, Dzip3 and Mex3b, as well as with th
145 The CRM domain is a recently recognized RNA binding domain found in three group II intron splici
146 ng and ribosome maturation (CRM) domain is a RNA-binding domain found in a plant-specific protein fam
147 rming canonical eight-repeat crescent-shaped RNA-binding domains found in classical PUF proteins.
149 library of eight aptamers and corresponding RNA binding domains fused to partial fragments of fluore
152 w of an important member of the RRM class of RNA-binding domains highlights the role of alternative s
153 structure of a ternary complex of human SLBP RNA binding domain, human 3'hExo, and a 26-nucleotide SL
154 RGG/RG domains are the second most common RNA binding domain in the human genome, yet their RNA-bi
156 The C-proximal motif within the N-terminal RNA binding domain in wheat eIF4B is required for intera
157 ins are the largest class of single-stranded RNA binding domains in the human proteome and play impor
158 recognition motif (RRM) is the most abundant RNA-binding domain in eukaryotes, and it plays versatile
160 promotes oogenesis and contains a number of RNA binding domains, including two RRMs and multiple LOT
161 r RNAs (mRNAs) via a high-affinity stem-loop RNA binding domain interaction, enabling high-throughput
164 c analyses revealed that the single-stranded RNA-binding domain is exclusively found in Prp3 ortholog
165 e protein to p62/SQSTM1, suggesting that the RNA-binding domain is responsible for the subcellular lo
168 c finger domain, which is the protein's main RNA binding domain, is most important for SG recruitment
169 e domain of RNase R, devoid of all canonical RNA-binding domains, is sufficient for this activity.
170 antages over classic methods for determining RNA-binding domains: it produces proteome-wide, high-res
173 two zinc knuckles and between the N-terminal RNA binding domains (KH and QUA2 domains) and the first
174 ine the roles of selected amino acids in the RNA binding domain, known as the tandem zinc finger (TZF
175 ge benchmark of 212 RNA binding and 6761 non-RNA binding domains (leave-one-out cross-validation).
177 hile intensity of the CLIP signal, number of RNA-Binding domains, location of the binding site on the
180 ndent termination functions of specific NusA-RNA binding domain mutants revealed an existence of Rho-
181 xpression through the function of an unusual RNA-binding domain named RAP (for RNA-binding domain abu
182 data, we were able to construct an isolated RNA-binding domain (Nop-RBD) that folds correctly as dem
184 We demonstrated previously that the NS1 RNA-binding domain (NS1(RBD)) interacts directly with th
185 step toward RNA recognition, we utilized the RNA binding domain of argonaute, implicated in RNA inter
191 A genetically encoded system based on the RNA binding domain of the Pumilio and FBF (PUF) proteins
192 our results reveal that the N-terminal Z-DNA/RNA binding domain of vaccinia virulence factor E3, whic
193 te of GRIA2 Furthermore, the double-stranded RNA binding domains of ADAR3 are required for repression
195 sid (N) protein that harbors two independent RNA binding domains of known structure, but poorly chara
196 somal particles requires the double-stranded RNA binding domains of NF90, while depletion of NF45 and
201 by mutation of a key residue in the putative RNA-binding domain of AID impairs recruitment of AID to
203 Here, we present crystal structures of the RNA-binding domain of Lassa virus NP in complex with ssR
204 de-acridine conjugates using portions of the RNA-binding domain of N protein (11- and 22- residue pep
206 nce coding regions and is facilitated by the RNA-binding domain of NS1, which can associate with ER m
210 we report the crystal structure of the DNA-/RNA-binding domain of Pur-alpha in complex with ssDNA.
213 panied by phylum-specific alterations in the RNA-binding domain of Srp54, the SRP protein subunit tha
214 cally dependent on the third double-stranded RNA-binding domain of Staufen1 and shuttling of Staufen1
215 result re-establishes the RRM as the primary RNA-binding domain of the hnRNP C tetramer and provides
216 d 2 in the fingers domain and T-motif in the RNA-binding domain of the telomerase reverse transcripta
219 ACT and TRBP suggest that the two N-terminal RNA-binding domains of each protein confer the observed
220 ments that correspond to the two independent RNA-binding domains of FMRP, in addition to the binding
221 mine whether the observed variability in the RNA-binding domains of four plant PUFs results in a pref
223 icing factors by combining sequence-specific RNA-binding domains of human Pumilio1 with functional do
224 ucture and RNA-binding properties of two key RNA-binding domains of IMP1, KH1 and KH2, and we build a
225 tion of N was shown to depend on both of the RNA-binding domains of N, as well as on the serine- and
227 n calorimetry experiments confirmed that the RNA-binding domains of PKR are sufficient and necessary
229 s work describes the interactions of the two RNA-binding domains of the nucleocapsid protein of a mod
230 R spectroscopy to demonstrate that the major RNA-binding domains of the two most distantly related IM
231 t the altered amino acids are located in the RNA-binding domains of two complex THOC2 structures, pot
232 ding of dsRNA to two dsRBDs (double-stranded RNA binding domains) of PKR modulates its own kinase act
234 nding proteins (RBPs): i.e. those with known RNA binding domains or otherwise implicated in RNA funct
235 oreover, Top3beta mutants lacking either its RNA-binding domain or catalytic residue fail to promote
236 unctional category 'RNA-binding', have known RNA-binding domains or have orthologs identified in mamm
237 n S4-like domain-an evolutionarily conserved RNA-binding domain previously identified in proteins inv
238 etry, we have identified the double-stranded RNA-binding domain protein Blanks to be an siRNA- and ds
239 ear RNase III Drosha and the double-stranded RNA-binding domain protein DGCR8 (DiGeorge syndrome crit
241 terogenous ribonucleoprotein A18 (hnRNP A18) RNA Binding Domain (RBD) and the arginine, glycine (RGG)
242 mplex between a fragment of 23S rRNA and the RNA binding domain (RBD) of the Bacillus subtilis DbpA p
246 the N-terminal, 4-zinc finger human (h) ZAP RNA-binding domain (RBD) and a CG dinucleotide-containin
247 nal protein with two distinctive domains, an RNA-binding domain (RBD) and an effector domain (ED) sep
249 ry site/segment (IRES)-the question of which RNA-binding domain (RBD) binds to which sites on the IRE
250 ues from both chains, namely residues in the RNA-binding domain (RBD) from one chain, and residues in
252 wo amino-acid residues in the NS1 N-terminal RNA-binding domain (RBD) that are required for binding d
254 In addition, OV20.0 binds directly to the RNA binding domains (RBDs) of PKR, and this interaction
255 hibitory interactions between the kinase and RNA binding domains (RBDs), but the structural details o
257 a genome-scale collection of RBPs and their RNA-binding domains (RBDs) and assessed their specificit
260 iewed as interconnected complexes (nodes) of RNA-binding domains (RBDs), whose integrated RNA-binding
263 ical separation of the Sec incorporation and RNA-binding domains revealed that they are able to funct
264 ut fungi, with divergent and distinctive PUF RNA binding domains, RNA-recognition motifs (RRMs), and
265 ft assays using a bacterially expressed PUM2 RNA binding domain showed specific binding using wild ty
269 86% success rate in its application to SCOP RNA binding domain superfamily (Structural Classificatio
271 cognition specificity and define a novel p65 RNA binding domain that initiates telomerase holoenyzme
272 ' end of the exon specify FMRP's RGG box, an RNA binding domain that interacts with G-quartet motifs.
274 ain, wheat eIF4B contains a novel N-terminal RNA binding domain that requires a short, lysine-rich co
275 trolled Mre11 abundance through a C-terminal RNA binding domain that selectively and directly binds M
276 idine Tract Binding Protein (PTBP1) has four RNA binding domains that each binds a short pyrimidine e
277 example to the repertoire of plant-specific RNA binding domains that emerged as a product of nuclear
278 ified and mutated several residues in the S1 RNA-binding domain that are important for interacting wi
279 ivity are mediated by sequences flanking the RNA-binding domain that bind specific molecular partners
280 ontains the PUA domain, a recently described RNA-binding domain that is found in several tRNA and rRN
282 ine in a conserved TPNK sequence in the SLBP RNA binding domain, thereby dissociating SLBP from the h
283 ntified hundreds of new RBPs that lack known RNA-binding domains, thus underscoring the complexity an
284 izes different surfaces of its alpha-helical RNA-binding domain to recognize several low-affinity bin
287 ncanonical poly(A) polymerase that lacks the RNA-binding domain typical of the canonical nuclear poly
288 (MHV), we constructed mutants in which each RNA-binding domain was replaced by its counterpart from
290 and RNA interactions of the wild-type U2AF65 RNA binding domain were compared with those of U2AF65 va
292 erved RNA recognition motif and a C-terminal RNA binding domain, wheat eIF4B contains a novel N-termi
293 PKR contains an N-terminal double-stranded RNA binding domain, which consists of two tandem double-
294 lian and viral mRNAs also interact with this RNA-binding domain with functional consequences to their
295 on, it correctly identified 31 of 75 unbound RNA-binding domains with 92% accuracy and 65% precision
296 e effector domain from non-H5N1 strains, the RNA binding domain within H5N1 NS1 exhibits modest struc
299 nstrate that its three previously elucidated RNA binding domains work together to provide eIF4F with
300 ch extends over a distance of 180 A from its RNA binding domain, wraps around the core domain consist