ライフサイエンスコーパス: RNA-binding motif

1 nce homology to any previously characterized RNA binding motif.

2 ins containing copies of the double-stranded RNA binding motif.

3 ough a region related to the double-stranded RNA binding motif.

4 hus appears to interfere with the N-terminal RNA binding motif.

5 esent a common, but previously unrecognized, RNA binding motif.

6 G boxes have been postulated to represent an RNA binding motif.

7 ns encompassing the N-terminal arginine-rich RNA binding motif.

8 acids 2 to 8 of the N-proximal arginine-rich RNA binding motif.

9 and in vivo despite its lack of a canonical RNA binding motif.

10 s) contains the unusual CCCH zinc finger, an RNA binding motif.

11 ucture but contains only one double-stranded RNA binding motif.

12 ondrial membrane, includes a K homology (KH) RNA-binding motif.

13 -disordered state and lacks any recognizable RNA-binding motif.

14 tually every clone contained a known DNA- or RNA-binding motif.

15 nd threonyl-tRNA synthetase, reveals a novel RNA-binding motif.

16 ike RNA-binding domains, and an RGG-box type RNA-binding motif.

17 ginine-rich C-terminus reminiscent of an RGG RNA-binding motif.

18 contain two copies of the RRM-type consensus RNA-binding motif.

19 licing regulation, we sought to identify its RNA-binding motif.

20 a remarkably versatile and highly conserved RNA-binding motif.

21 uggests that this protein fold is an ancient RNA-binding motif.

22 the mRNA through RNA recognition motif-type RNA binding motifs.

23 localization signal and two double-stranded-RNA binding motifs.

24 is novel and lacks all of the characterized RNA binding motifs.

25 ons, but does not include other recognizable RNA binding motifs.

26 contain three characteristic RNP2/RNP1-type RNA binding motifs.

27 AMV coat protein lacks previously identified RNA binding motifs.

28 P-granule component in lacking recognizable RNA binding motifs.

29 ine-polycytidylic acid via its double-strand RNA binding motifs.

30 s appear to form a novel gene family sharing RNA-binding motifs.

31 ic modifiers that bind RNA without canonical RNA-binding motifs.

32 transcriptase domain but retaining the known RNA-binding motifs.

33 It interacts with NF90's double-stranded RNA-binding motifs.

34 y mutations in the RBM10 gene, which encodes RNA binding motif 10.

35 RSF1, we showed that several residues in the RNA-binding motif 2 interact with the N-terminal region

36 Disruption of the implicated intramolecular RNA-binding motif 2-RS domain interaction impairs both t

37 RNA-binding motif 20 (RBM20) is a splicing factor primar

38 The splicing factor RNA-binding motif 20 (RBM20) regulates the contour lengt

39 he RNA recognition motif (RRM) of one of the RNA binding motif-20 alleles was floxed and that express

40 Inhibition of the RNA binding motif-20-based titin splicing system upregul

41 ly through inhibition of the splicing factor RNA binding motif-20.

42 nhanced expression of the cold-shock protein RNA binding motif 3 (RBM3) is highly neuroprotective bot

43 nscription dynamics of cold-response protein RNA Binding Motif 3 (Rbm3).

44 Here, we demonstrate that RNA-binding motif 3 (RBM3) is highly expressed in lung I

45 24 h, revealed significant changes only for RNA-binding motif 3 (Rbm3).

46 Pharmacologic depletion of RNA-binding motif 39 (RBM39) using aryl sulfonamides rep

47 g sequences identified a novel fusion of the RNA binding motif 6 (RBM6) gene to CSF1R gene generated

48 tely 120 amino acids forming another type of RNA binding motif, a RGG box.

49 d by the LIN-28 protein's unusual pairing of RNA-binding motifs: a cold shock domain (CSD) and a pair

50 1 to 200, but not R312A substitution in the RNA binding motif, abolished the ability of the VP35 pro

51 In addition, yeast Nep1 binds to a 6-nt RNA-binding motif also found in 18S rRNA and facilitates

52 Mutations in the eIF3c RNA-binding motif also reduce 40S ribosomal subunit bind

53 dsRNA binding motifs, or the isolated first RNA binding motif (amino acids 1-123).

54 The conservation of the RNA binding motifs among Y-box protein family members ra

55 contain two copies of a double-stranded (ds) RNA binding motif and bind strongly to dsRNA.

56 RBMS3 contains two pairs of RNA binding motifs and is very closely related to the st

57 though a HEXIM1 dimer contains two potential RNA binding motifs and ultimately recruits two P-TEFb mo

58 3 complex, is a 66 to 68-kDa protein with an RNA-binding motif and a cap-binding domain.

59 th an autosomal hnRNPG gene that contains an RNA-binding motif and one of the four SRGY repeats found

60 e large proteins characterized by N-terminal RNA-binding motifs and a highly conserved C-terminal SPO

61 ive-helix bundle that is distinct from known RNA-binding motifs and instead is similar to the carboxy

62 DSEF-1 protein contains three RNA-binding motifs and is a member of the hnRNP H family

63 t differ in the number of tandem zinc-finger RNA-binding motifs and subcellular localization, is expr

64 at does not contain any previously described RNA-binding motifs and that contains only 2 of the 11 pr

65 U12 splicing factor, zinc finger CCCH-type, RNA binding motif, and Ser/Arg rich 2/Rough endosperm 3

66 which consists of two tandem double-stranded RNA binding motifs, and a C-terminal kinase domain.

67 ly related proteins that contain a predicted RNA-binding motif, and both loci are expressed exclusive

68 terminus to include a single double-stranded RNA-binding motif, and that T20H4.4 occupies the second

69 inal region, consisting of a double-stranded RNA-binding motif, and the N-terminal region (vZ(E3L)),

70 Y chromosome that encode proteins containing RNA-binding motifs, and both have been described as cand

71 no acid sequence contains four arginine-rich RNA-binding motifs, and one segment shows strong homolog

72 inal domain, containing a number of putative RNA-binding motifs, and the catalytic function of the ca

73 However, the RNA binding motifs are not sufficient for trans-activati

74 recognition patterns, as well as the protein-RNA binding motifs, are then identified and analyzed.

75 apsid protein (CP) contains an arginine-rich RNA binding motif (ARM) that is also found in the CPs of

76 RNA-binding peptides using the arginine-rich RNA-binding motif as a framework.

77 ossess functionally distinct double-stranded RNA-binding motifs as measured with synthetic double-str

78 g ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.

79 are similar in fold to previously identified RNA binding motifs, despite limited sequence homology.

80 complex and contains a double-stranded (ds)-RNA-binding motif (DRM).

81 cid residues within the double-stranded (ds) RNA binding motif (dsRBM) of the vaccinia virus E3 prote

82 ctors containing one or more double-stranded RNA binding motif (dsRBM) that play important roles in s

83 tandem copies of a conserved double-stranded RNA binding motif, dsRBM1 and dsRBM2.

84 g protein, NF90 contains two double stranded RNA-binding motifs (dsRBMs) and interacts with highly st

85 ADAR2 contains two tandem double-stranded RNA-binding motifs (dsRBMs) that are not only important

86 ot the other, of ADAR2's two double-stranded RNA-binding motifs (dsRBMs), and the correct placement o

87 oughput in vitro binding reveals a consensus RNA-binding motif engaged by the core ARID domain.

88 efined by the presence of a highly conserved RNA binding motif first described in the mei2 gene of th

89 eIF2D requires its RNA-binding motif for regulation of 5' leader-mediated A

90 ed residues reminiscent of the arginine-rich RNA-binding motif found in a wide variety of proteins.

91 mino acids of RH II/Gu can be replaced by an RNA binding motif from nucleolar protein p120 without a

92 The RBM (RNA-binding motif) gene family on the human Y chromosome

93 and the larger ones remove some of the RBM (RNA Binding Motif) genes, but none of the deletion males

94 U2AF1 carries hotspot mutations in its RNA-binding motifs; however, how they affect splicing an

95 gosaccharide-binding (OB) fold is a ssDNA or RNA binding motif in prokaryotes and eukaryotes.

96 in agreement with the presence of a putative RNA binding motif in the deduced amino acid sequence.

97 of protein-RNA interactions, defined by four RNA binding motifs in RNase III and three protein-intera

98 Part of it is highly homologous to the TAR RNA-binding motif in the human immunodeficiency virus ty

99 xperiments, we identify two highly conserved RNA-binding motifs in eIF3 that direct translation initi

100 ese findings suggest that individual KH-like RNA-binding motifs in ICP27 may be involved in binding d

101 RNA profiling and bioinformatics to identify RNA-binding motifs in mRNAs that either enter or exit th

102 dered domains adjacent to well characterized RNA-binding motifs in other promiscuous RNA-binding prot

103 possible biological significance of putative RNA-binding motifs in the N and palm domains of RB69 gp4

104 ractions with basic residues and Cys-His box RNA-binding motifs in the nucleocapsid.

105 apart, matching the distance between the two RNA-binding motifs in the Rev dimer.

106 rich (RS) domain but does not have any known RNA-binding motifs, indicating that it is not a member o

107 editing catalytic polypeptide 3 family) have RNA-binding motifs, invade assembling human immunodefici

108 A PTBP2 consensus RNA binding motif is enriched in the TDP-43 RIP-seq libr

109 The arginine-rich RNA binding motif is found in a wide variety of proteins

110 rther reveals that the suggested nucleoporin RNA binding motif is unlikely to bind to RNA.

111 which contains two putative double-stranded RNA binding motifs, is essential for the in vivo functio

112 tact cold-shock domain (CSD), containing two RNA-binding motifs, is required to localize MSY2 to the

113 predicted alpha and beta structures of this RNA binding motif lack who function.

114 All three RNA-binding motifs (LAM, RRM1, and RRM2) of La/SSB are r

115 a CLIP-seq experiment, we find that EWS-FLI1 RNA-binding motifs most frequently occur adjacent to int

116 Furthermore, the RNA-binding motif mutants are defective for their export

117 tein with a loss-of-function mutation in the RNA-binding motif no longer binds to the mRNA cap struct

118 This analysis has identified a unique RNA binding motif of alternating basic and aromatic resi

119 The helix-loop groove RNA binding motif of T4 RegA protein is fully conserved

120 selectively and strongly interacted with the RNA-binding motif of eCIRP, thereby preventing eCIRP's b

121 differs from the (A-R-N) tripartite poly(A) RNA-binding motif of Escherichia coli Hfq whereby the Sa

122 HDV RNA, indicating that both the NLS and an RNA-binding motif of HDAg are required for the RNA-trans

123 Mutations in the RNA-binding motif of subunit eIF3a weaken eIF3 binding t

124 However, the RNA-binding motif of Uap56p is critical for nuclear expo

125 e functional importance of each of the three RNA-binding motifs of ADAR1 varied with the specific tar

126 of the nuclear localization signal (NLS) or RNA-binding motifs of HDAg resulted in the failure of nu

127 eraction that enlists both of the N-terminal RNA-binding motifs of the protein with separate surfaces

128 ing of well-characterized libraries of guide RNAs, binding motifs of synthetic operators, transcripti

129 The structure reveals a bipartite RNA-binding motif on the distal face that is composed of

130 e discovery of oncogenic activation of RBMY (RNA-binding motif on Y chromosome), which is absent in n

131 RNA-binding motif prediction indicated multiple binding

132 Dom34p contains an RNA binding motif present in several ribosomal proteins

133 l analysis of the three double-stranded (ds) RNA binding motifs present in ADAR1 revealed a different

134 ntaining octamer-binding protein (NONO), and RNA binding motif protein 14 (RBM14), all reported to be

135 Mutations in RNA binding motif protein 20 (RBM20) are a common cause

136 ss-of-function mutation in the gene encoding RNA binding motif protein 20 (Rbm20) as the underlying c

137 By analyzing the isoforms in the presence of RNA Binding Motif Protein 20 (RBM20) mutations associate

138 RBM20 (RNA binding motif protein 20) cardiomyopathy is a severe

139 ng targeting splicing factors such as RBM20 (RNA binding motif protein 20) to adjust isoform ratios o

140 sol treatment also elevates the level of the RNA binding motif protein 24 (RBM24) and RNA binding mot

141 RNA binding motif protein 25 (RBM25) is a putative splic

142 the RNA binding motif protein 24 (RBM24) and RNA binding motif protein 38 (RBM38) proteins, two multi

143 hat associates with the core splicing factor RNA binding motif protein 39 (RBM39) and localizes to nu

144 d bestrophin 1 (BEST1), transcription factor RNA binding motif protein 39 (RBM39), inflammatory media

145 indisulam promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiq

146 r genome resequencing studies, we identified RNA binding motif protein 47 (RBM47) as a suppressor of

147 We found that the maize (Zea mays) RNA binding motif protein 48 (RBM48) is a U12 splicing f

148 exon 9 of RBM20, encoding ribonucleic acid (RNA) binding motif protein 20.

149 RNA-binding motif protein 10 (RBM10) is an RNA-binding p

150 as well as in cellular mRNAs, is mediated by RNA-binding motif protein 15 (RBM15) and its paralogue R

151 RNA-binding motif protein 15 (RBM15) is involved in the

152 RNA-binding motif protein 20 (RBM20) is essential for no

153 zygous missense mutations were identified in RNA-binding motif protein 20 (RBM20), a spliceosome prot

154 n of several cardiac splice factors, such as RNA-binding motif protein 20 and SF3B1, not only provide

155 Disease-causative variants in RBM20-encoded RNA-binding motif protein 20 cause a severe arrhythmogen

156 RBM20 (RNA-binding motif protein 20) is a vertebrate- and muscl

157 RBM24 (RNA-binding motif protein 24) is known as a tissue-speci

158 n of cellular stress response proteins RBM3 (RNA-binding motif protein 3) and CIRP (cold-inducible RN

159 inate lyase, neuronal nitric-oxide synthase, RNA-binding motif protein 3, peroxiredoxin I, proteasome

160 Here, we identify RNA-binding motif protein 33 (RBM33) as a previously unr

161 RNA-binding motif protein 38 (Rbm38), also called RNPC1

162 a novel role for an emerging cancer target, RNA-binding motif protein 39, as a metabolic sensor of t

163 RBP negatively regulating ERV expression was RNA-binding motif protein 4 (RBM4).

164 we show that following genotoxic stress, the RNA-binding motif protein 7 (RBM7) stimulates RNA polyme

165 e-activated receptor-2) and RBFOX2 (encoding RNA-binding motif protein 9), were concurrently associat

166 the unprecedented finding that the conserved RNA-binding motif protein, RBM24, positively controls So

167 to result in the fusion of two novel genes, RNA-binding motif protein-15 (RBM15), an RNA recognition

168 coding the pathogenic R636S variant of human RNA-binding motif protein-20 (RBM20), we discovered that

169 characterization of a novel cofactor, RBM46 (RNA-Binding-Motif-protein-46), that can facilitate A1 to

170 finity despite the absence of a recognizable RNA binding motif (RBM).

171 An RNA-binding motif (RBM) gene family has been identified

172 RNA-binding motif (RBM) genes are found on all mammalian

173 ars to be a new member of a highly conserved RNA-binding motif (RBM) protein family that is highly co

174 ction-mediated expression of either of these RNA binding motif (RBMs) facilitates the inclusion of ex

175 ular biology through binding single-stranded RNA binding motifs (RBMs).

176 Despite lacking a known RNA-binding motif, recombinant UIEF1 interacted with RNA

177 The fusilli gene encodes a protein with RNA binding motifs related to those in mammalian hnRNP F

178 ur understanding of binding partners and PAN RNA binding motifs remains incomplete.

179 Two RNA-binding motifs, RI and RII, were present in exons 4

180 WhGRP-1 contains two conserved domains, the RNA-binding motif (RNP motif) combined with a series of

181 Within this domain are two highly conserved RNA-binding motifs, RNP-1 and RNP-2.

182 tranded beta-barrel structure containing two RNA-binding motifs, RNP1 and RNP2.

183 ine and histidine residues that resemble the RNA binding motifs seen in some other proteins.

184 Recently, our group identified the RNA Binding Motif Single Stranded Interacting Protein 3

185 ion of the HIF1A inhibitor YC1 (now known as RNA-binding motif, single-stranded-interacting protein 1

186 in components of P granules contain putative RNA-binding motifs, suggesting that RNA is involved in e

187 ead association between polyQ expansions and RNA-binding motifs, suggesting that this is a broadly ex

188 h p33, contain an arginine- and proline-rich RNA-binding motif (termed RPR, which has the sequence RP

189 KH domains are RNA binding motifs that usually occur in tandem repeats

190 The K homology (KH) module is a widespread RNA-binding motif that has been detected by sequence sim

191 , we identified a highly conserved, putative RNA-binding motif that is critical for PRF transactivati

192 purred the evolution of diverse noncanonical RNA-binding motifs that perform organelle-specific funct

193 We functionalize these polymers with RNA-binding motifs that sequester polyadenine-containing

194 ose that this betaalphaalphabeta fold is the RNA binding motif, the minimum structural requirement fo

195 lthough both contain the consensus VIGxxGxxI RNA-binding motif, the protein folds are probably differ

196 FMRP is methylated on the high-affinity RNA-binding motif, the RGG box, at positions 533, 538, 5

197 The 62-kD protein contained two types of RNA-binding motifs, the consensus sequence RNA-binding d

198 TUTases have C-terminal folds reminiscent of RNA binding motifs, thus indicating the presence of nume

199 The similarity of these R2 RNA binding motifs to those of telomerase and group II i

200 aromatic residues outside the canonical RRM RNA-binding motifs to encase and wrench open the RNA, wh

201 n HEXIM1 C-terminal to its previously mapped RNA-binding motif was also required for interactions bet

202 , any one of the three previously identified RNA-binding motifs was sufficient to confer the RNA-tran

203 27 N-terminal peptide, including the RGG box RNA binding motif, was expressed and its binding specifi

204 In addition to known RNA-binding motifs, we detected several protein domains

205 nserved amino acids throughout the SBP2 L7Ae RNA binding motif were mutated to alanine in clusters of

206 orts viral RNA through an N-terminal RGG box RNA binding motif, which is necessary and sufficient for

207 es N-7 pol may be structurally related to an RNA-binding motif, which appears to be conserved among a

208 ed that MSI-2 interacts specifically with an RNA binding motif within the 5' untranslated region (5'U

209 ial positioning of splice sites, codons, and RNA-binding motifs within an mRNA is strongly associated

210 seeds and the potential contribution of the RNA-binding motifs within miRNAs/isomiRs and mRNAs to th

211 Six gene families, including RBMY (RNA binding motif, Y chromosome), DAZ (deleted in azoosp

212 The RBMY (RNA-binding motif, Y chromosome) gene family encodes a g